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O4.1 BRIEF MOTIVATIONAL INTERVENTION TO REDUCE ALCOHOL CONSUMPTION IN YOUNG PATIENTS IN A FRENCH EMERGENCY DEPARTMENT {#article-title-2} Background. Alcoholic intoxication (AI) in young people is an important problem in emergency departments (EDs). Aim - To establish the effectiveness of a Brief Motivational Intervention (BMI) in reducing alcohol consumption among young patients admitted in a French ED for AI. Methods. Two-group simple blind randomised controlled trial. From September 2011 to July 2012, patients aged 16 to 24 who tested positive for blood alcohol content of 0.5g/l or above were randomised, with stratification according to patient's age (16-17 or 18-24), between intervention (BMI performed by a psychologist in the ED setting followed by a phone booster session at one and two months) and controls (delivery only of an information leaflet and a list of addresses of services for alcohol misuse). The principal criteria used to assess the reduction of alcohol use at 3 months follow-up was the number of alcoholic drinks in the last week. Results. A total of 263 patients (controls 131, intervention group 132, mean age 20, men 72%) were randomized. Attrition accounted for 38% in controls and 43% in intervention group. Data analysis was conducted for a Poisson frequency distribution and showed no significant difference in effectiveness between the two conditions (OR 0.93 [0.64; 1.36]). All secondary outcomes were also not influenced by the intervention (including the number of AIs in the last month). Conclusions. This study did not detect a significant effect of Brief Motivational Intervention in reducing alcohol consumption after hospitalization for alcoholic intoxication in emergency department in young people. # O4.2 HARMFUL ALCOHOL CONSUMPTION IN HEALTH-WORKERS: RESULTS OF A SCREENING STUDY {#article-title-3} Background. In Italy national alcoholism risk prevention programs to assess number for year of accidents in health workplaces is actually in progress leaded by Health Minister and Regional administration. Particularly, prevention program acts consist in comprehensive informations for health workers and their co- workers, about prevention and identification of alcoholism related risks. Aims. To assess the rate of harmful alcohol consumption in a population of health workers in Padua. Materials and methods. Modified CAGE questionnaire was sent to 5590 health-workers in Padua. Anonymous questionnaires were collected in dedicated boxes. Results. 654/5590 (11.7%) subjects performed the test (M: 150, F: 504, mean age 42.9 yrs, range 28-65). The professional role was nurse in 300/654 (45,9%), physician 83 (12,7%), administrator 80 (12,2%), other 191 (29,2%). 57/654 (8.7%) had positive questionnaire for alcohol abuse or dependence: 33/57 (57,9%) had suspicion, 15 (26.3%) high probability and 9 (15.8%) were certainly alcohol abusers. 37/504 females (7,3%) and 20/150 males (13,3%) showed positive CAGE test. The professional role indicated positive test in 26/300 (8,7%) nurses, 9/83 (10,8%) physicians, 1180 (1,2%) administrator and 21/191 (11%) other professional roles. Conclusions. The number of tests performed is unsatisfactory, particularly among males and physicians. Our data suggest that harmful alcohol consumption is present in health-workers, more frequently in male sex. Physicians demonstrate an high prevalence of positive test. These data also suggests that the awarness of alcohol related problems doesn't reduce the probability of harmful consumption. A screening study can be useful to identify harmful alcohol users among the selective population of health-workers. # O4.3 BRIEF INTERVENTION IN PRIMARY HEALTH CARE FOR ALCOHOL USERS: AN EXPERIENCE IN PORTUGAL {#article-title-4} Introduction. The professionals of primary health care have a crucial role in screening individuals with risk consumption and harmful alcohol. The effectiveness of brief interventions in reducing alcohol consumption however, in Portugal its use is not yet widespread in particularly in primary care. Objective. to evaluate the effect of Brief Interventions in reducing excessive alcohol consumption on users accessing health center services, Coimbra, Portugal. Methods. A pre-trial, with a single group, and the assessment before the intervention (5 months). The sample included 45 patients (19 females, Mean= 48 age, SD = 15.199), enrolled in the Health Center Ansiao. We used a structured interview, using a questionnaire that included the AUDIT (Alcohol Use Disorders Identification Test), to evaluate the level of risk in relation to alcohol consumption. Interventions were made by previous protocol based on the level of risk identified, for data analysis resorting to the Wilcoxon test. Results. At baseline: 86.7% were at risk level I, 11.1% in the risk level II and 0% in the risk level III. In folow-up five months after the brief interventions, 95.6% were at risk level I, 2.2% in the risk level II and 0% in the risk level III. There was a positive effect on the progress of participants in respect to the levels of risk, with statistical significance (p = 0.046). Conclusions. Brief Interventions took effect in lowering and stabilizing the risk levels of alcohol consumption, reinforcing the importance of integration of Brief Interventions in Primary Health Care. # O4.4 UNIVERSAL SCHOOL-BASED PREVENTION INTERVENTION AND ALCOHOL USE {#article-title-5} Background. The Unplugged, a prevention intervention based on the Comprehensive Social Influence model, was implemented to reduce the risk of alcohol use in Czech adolescents. We investigated the effect of the Unplugged on the reduction of drunkenness. Methods. A randomized controlled prevention trial was conducted over 33 months. 1,874 6th-graders (mean age 11.82 years) completed the baseline testing. We compared self-reported drunkenness in control and intervention groups. Using logistic regression we study relationship between drunkenness and other variables such as gender, peer and parents effect, leisure time, ideas of hurting oneself, safe sex and school grades. Results. We find a significant effect of the Unplugged on the reduction of drunkenness. Male adolescents with unstructured leisure time activities and lower parents control report higher frequency of drunkenness. Idea of hurting oneself and unsafe sex is also associated with higher risk of getting drunk. Conclusion. We present evidence on the composition of risk profiles in adolescents who are engaged in high-risk alcohol consumption. Besides the intervention a screening tool should be used to identify adolescents who are eligible for complementary selective and/or indicated prevention interventions.