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1. CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn’s disease

Author

L. Krabbendam, B. A. Heesters, C. M. A. Kradolfer, N. J. E. Haverkate, M. A. J. Becker, C. J. Buskens, W. A. Bemelman, J. H. Bernink, and H. Spits

Subjects
Science
Abstract

Phenotypic markers that overlap between ILC1 and NK populations have impacted the robust and specific analysis of these immune cell populations. Employing scRNA sequencing here the authors identify CD127+ CD94+ innate lymphoid cells that express granulysin and perforin and are expanded in patients with Crohn’s disease.

Published
2021
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