Search

Hookworm-related cutaneous larva migrans is caused by the subcutaneous migration of hookworm larvae. The characteristic sign is a serpiginous cutaneous track. Folliculitis is an uncommon clinical manifestation. We report a case of hookworm-related folliculitis in a woman performing skin bleaching. A 33-year-old woman presented with a widespread cutaneous eruption made of erythematous and itchy follicular papulo-nodules, with erythematous serpiginous tracks, about 5-10cm long and numerous streaks of scratching, located on the limbs, buttocks and trunk. The cutaneous lesions occurred two days after contact with the floor of a warehouse contamined by faeces of cats. The lesions have been evolving for a week and have been treated with antibiotics without success. Clinical examination found cutaneous atrophy, purple stretch marks and hyperpigmentation of dorsal parts of fingers joints. The patient reported having been using bleaching cosmetics containing topical steroids and hydroquinone for twelve years. She was cured within 4 weeks with oral albendazole 400mg per day during 7 consecutive days.

Hookworm-related cutaneousLa folliculite ankylostomienne est une forme folliculaire de

Introduction La larva migrans cutanee ankylostomienne (LMCA) est due a la penetration transcutanee accidentelle et a la survie en impasse parasitaire chez l’homme de larves d’ankylostomes d’origine animale. La forme furonculoide (LMCAF) est une forme atypique rarement observee. Nous rapportons un cas de LMCAF sur terrain de depigmentation. Observation Une patiente de 33 ans a ete vue en consultation pour une eruption de papulo-nodules folliculaires, tres prurigineux, erythemateux, dont certains etaient excories, coexistant avec des cordons serpigineux erythemateux, d’environ 5–10 cm, et de nombreuses stries de grattage, le tout dispose de facon eparse sur les zones convexes des membres, du dos, des fesses et de l’abdomen. Les lesions evoluaient depuis une semaine et etaient traitees avec des antibiotiques sans succes. Cette symptomatologie serait survenue deux jours apres le contact avec le sol d’un entrepot. Le reste de l’examen physique a trouve des stigmates de depigmentation a type d’atrophie cutanee, de vergetures pourpres et une hyperpigmentation des espaces interphalangiens. La patiente a declare utiliser des cosmetiques depigmentants depuis douze ans. La LMCAF diffuse sur terrain de depigmentation artificielle a ete evoquee. Un traitement a base d’albendazole 400 mg/jour pendant 7 jours a permis d’obtenir une evolution favorable avec une disparition totale du prurit et des lesions en 2 semaines. Discussion La LMCAF est secondaire a la migration des ankylostomes dans le canal folliculaire ou le derme. Dans la forme classique, ils migrent au sein de l’epiderme grâce a la secretion de proteases. Depourvus de collagenases, ils depassent rarement la membrane basale. Notre cas clinique suggere le role de l’atrophie cutanee et de l’immunodepression locale induites par les produits depigmentants. L’association de cordons serpigineux typiques constitue une aide au diagnostic et permet d’eliminer les folliculites bacteriennes et la scabiose frequentes sur ces terrains. Conclusion Notre observation pose le probleme de la pathogenie de la LMCAF. Dans notre contexte, la LMCAF peut etre sujette a des errances diagnostiques.

The aim of this study was to document the epidemiological and clinical characteristics of anogenital dermatoses (AGDs) in Cotonou, Benin.This retrospective, descriptive study, conducted in the Department of Dermatology-Venereology at the National University Hospital of Cotonou, examined medical records of admissions and outpatient consultations for the 5-year period 2005-2009 and included the records of all patients with a clinical diagnosis of AGD.The prevalence of AGD in our series was 2.6% and the prevalence of sexually transmitted AGDs (STIs) was 1.3%. The sex ratio (M:F) was 2.5, and the patients' average age was 31.1 years. AGDs were classified as infectious (77%), inflammatory (12.6%), non-infectious tumors (3.7%), physiological (2.1%), psychodermatoses (2.1%), non-infectious ulcers (1.6%), and dyschromia (1%). STIs accounted for 44% of the AGDs: condyloma (65.5%), genital herpes (19%), urethritis (8.3%), and chancroids (4.8%). The primary sites in men were the foreskin, the groin, the scrotum, and the glans, and in women, the labia majora, the groin, the labia minora, and the anal cleft.AGDs were relatively rare in hospital consultations in Cotonou. They were mainly infectious (viral or fungal), and nearly half were STIs.