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5. Trends in Viral Respiratory Infections During COVID-19 Pandemic, South Korea

Author

Yum, Sujin, Hong, Kwan, Sohn, Sangho, Kim, Jeehyun, and Chun, Byung Chul

Subjects
Epidemics -- Statistics -- South Korea, Respiratory tract infections -- Statistics, Health
Abstract

The government of South Korea has implemented various measures to respond to the coronavirus disease (COVID-19) pandemic since January 20, 2020, when a case was officially reported in South Korea [...]

Published
2021
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25. Effects of Severe Acute Respiratory Syndrome Coronavirus Vaccination on Reinfection: A Community-Based Retrospective Cohort Study.

Author

Gim, Hyerin, Lee, Seul, Seo, Haesook, Park, Yumi, and Chun, Byung Chul

Subjects
SARS disease, CORONAVIRUSES, REINFECTION, CORONAVIRUS diseases, COVID-19, VACCINATION
Abstract

Background: Coronavirus disease 2019 (COVID-19) is a disease that is characterized by frequent reinfection. However, the factors influencing reinfection remain poorly elucidated, particularly regarding the effect of COVID-19 vaccination on preventing reinfection and its effects on symptomatology and the interval until reinfection. Methods: This retrospective cohort study examined patients with severe acute respiratory syndrome coronavirus reinfection between January 2020 and February 2022. This study included patients aged >17 years who were reinfected at least 90 days between two infections with severe acute respiratory syndrome coronavirus. The main outcome measure was a reduction in symptoms during reinfection, and reinfection interval. Results: Overall, 712 patients (average age: 40.52 ± 16.41 years; 312 males) were included. The reduction rate of symptoms at reinfection than that at first infection was significantly higher in the vaccinated group than in the unvaccinated group (p < 0.001). The average reinfection interval was 265.81 days. The interval between the first and second infection was 63.47 days longer in the vaccinated group than in the unvaccinated group. The interval was also 57.23 days, significantly longer in the asymptomatic group than in the symptomatic group (p < 0.001). Conclusions: Besides its role in preventing severe acute respiratory syndrome coronavirus infection, vaccination reduces the rate of symptomatic reinfection and increases the reinfection interval; thus, it is necessary to be vaccinated even after a previous infection. The findings may inform the decision to avail COVID-19 vaccination. [ABSTRACT FROM AUTHOR]

Published
2023
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39. HOSPITAL-BASED SURVEILLANCE OF INFECTION-RELATED MORTALITY IN SOUTH KOREA

Author

Choi, Jun Yong, Cheong, Hee-Jin, Chun, Byung Chul, Park, Hye Kyung, Lee, Han Sung, Lee, Hagyung, Kim, Sang IL, Kim, Min Ja, Kim, Sung Soo, Chang, Hyun-Ha, Lee, Sun Hee, Park, Kyung Hwa, Chung, Doo Ryeon, Chung, Jin-Won, Park, Dae Won, Choi, Young Hwa, Choo, Eun Ju, Jeong, Hye Won, Yoon, Hee Jung, Jeon, Min-Hyuk, Kim, Young Keun, Kim, Hyo Youl, Shin, Sang Yop, and Kim, June Myung

Published
2009

43. 1438Dynamics of inter-farm transmission of highly pathogenic avian influenza integrating vehicle movements and phylogenetic information

Author

Chun Byung Chul and Dae-Sung Yoo

Subjects
Genetics, Phylogenetic tree, Epidemiology, Highly pathogenic, General Medicine, Biology, medicine.disease, medicine.disease_cause, Influenza A virus subtype H5N1, Pathogenic organism, law.invention, Transmission (mechanics), Idiopathic pneumonia syndrome, law, Genotype, medicine, Poultry meat
Abstract

Background Highly pathogenic avian influenza (HPAI), a zoonotic infectious disease, has been considered a severe threat to public health. The fundamental prevention and control strategy against HPAI includes minimizing the outbreaks of poultry holdings where the virus primarily spreads through animal trade and poultry production associated vehicle movement (PPVM). However, very few attempts have been made to elucidate the association between PPVM and HPAI transmission compared to studies on poultry trade. Therefore, our study aimed to elucidate the role of PPVM on HPAI transmission. Methods We performed network analysis using PPVM data based on a global positioning system (GPS), with phylogenetic information of the HPAI virus for reliable estimation. Moreover, the contribution of PPVM to HPAI infection was estimated by Bayesian inference. Results The network analysis revealed that the connection via PPVM between the same genetic group of infected premises (IPs) was more prevalent than that of different genotype IPs. Moreover, the similarity of farm poultry species and the overlapped integrators between inter-linked IPs was associated with potential transmission route formation. Additionally, the contribution of PPVM among phylogenetically clustered IPs was estimated to have 28.25% of HPAI infections in IPs on average. Conclusions HPAI control strategies including targeted movement restriction and standstill should be established against the HPAI transmission via PPVM. Key messages This is a solid and novel study depicting the need for combining epidemiological analysis with data regarding molecular epidemiology of pathogens.

Published
2021

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