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1. Discovery of BI 135585, an in vivo efficacious oxazinanone-based 11β hydroxysteroid dehydrogenase type 1 inhibitor

3. Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket

4. Spirocyclic ureas: Orally bioavailable 11β-HSD1 inhibitors identified by computer-aided drug design

5. Optimization of orally bioavailable alkyl amine renin inhibitors

6. Design and optimization of renin inhibitors: Orally bioavailable alkyl amines

7. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility

8. Structure-Based Design and Synthesis of 1,3-Oxazinan-2-one Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1

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