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15 results on '"Caglio, MARCELLA MARIA"'

3. Brain correlates of alexithymia in eating disorders: A voxel-based morphometry study

Author

D'Agata, Federico, Caroppo, Paola, Amianto, Federico, Spalatro, Angela Valentina, Caglio, MARCELLA MARIA, Bergui, Mauro, Lavagnino, Luca, Righi, Dorico, ABBATE DAGA, Giovanni, Pinessi, Lorenzo, Mortara, Paolo, and Fassino, Secondo

Subjects
Adult, Neuroscience (all), Anorexia Nervosa, Adolescent, Depression, Brain, Neuroimaging, eating disorders, Magnetic Resonance Imaging, alexithymia, anorexia nervosa, bulimia nervosa, voxel-based morphometry, Neurology (clinical), Neurology, Psychiatry and Mental Health, Young Adult, Case-Control Studies, Parietal Lobe, Humans, Female, Affective Symptoms, Gray Matter, Bulimia Nervosa
Abstract

Alexithymia is a personality trait that consists of difficulty in identifying and acknowledging one's own and others' feelings. Recent studies reported that alexithymia is present in both anorexia (AN) and bulimia nervosa (BN). Brain morphological studies on healthy subjects showed that alexithymia correlates with several brain regions involved in emotions processing. The aim of this study was to investigate the anatomical correlates of alexithymia in AN and BN.We performed a voxel-based morphometry study on 21 patients with AN and 18 with BN. Seventeen healthy subjects were used as a control group. Alexithymia, depression and anxiety were assessed with self-administered questionnaires and correlated to gray matter (GM) density in each group.In BN, alexithymia was correlated with the GM of the parietal lobe, in particular of the right angular gyrus. The correlation was predominantly linked with Difficulty Describing Feelings. In AN, we did not find correlations between GM and alexithymia.In BN, our results support the hypothesis that this trait may represent a relevant pathogenic or maintenance factor that contributes to relational difficulties, present in this pathology. In AN, the lack of correlation between GM volume and alexithymia may be influenced by atrophy in several brain regions that in turn can be, as previously reported, a consequence of caloric restriction. Also, the nature of alexithymia may be different from that of BN and controls and this trait could be secondary to a psychopathologic process specific to AN.

Published
2014

7. Abstracts of the Twentieth Meeting of the European Neurological Society. June 19-23, 2010. Berlin, Germany

Author

P. Caroppo, F. D’Agata, Caglio, MARCELLA MARIA, Rizzi, Laura, Croce, Michelle, Pacca, Paolo, Fontanella, Marco Maria, Ferrio, F., Coriasco, Mario Gino, and Bradac, Gianni Boris

Subjects
urinary incontinence, depression, NPH, apathy, Normal Pressure Hydrocephalus, NPH, motor impairment, urinary incontinence, depression, anxiety, apathy, Normal Pressure Hydrocephalus, anxiety, motor impairment
Published
2010

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