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404 results on '"Caio, Giacomo"'

2. List of contributors

Author

Aimo, Cristina, primary, Aronico, Nicola, additional, Auricchio, Renata, additional, Barone, Michele, additional, Biagi, Federico, additional, Bianchi, Paola Ilaria, additional, Bibbò, Stefano, additional, Broglio, Giacomo, additional, Caio, Giacomo, additional, Calabrese, Emma, additional, Cammarota, Giovanni, additional, Caproni, Marzia, additional, Carroccio, Antonio, additional, Castellaneta, Stefania, additional, Catassi, Carlo, additional, Catassi, Giulia, additional, Ciacci, Carolina, additional, Ciccocioppo, Rachele, additional, Copparoni, Roberto, additional, Corazza, Gino Roberto, additional, Corrà, Alberto, additional, Cristofori, Fernanda, additional, Dargenio, Vanessa Nadia, additional, De Giorgio, Roberto, additional, De Lisi, Giuseppe, additional, De Micco, Ida, additional, Di Sabatino, Antonio, additional, Di Stasio, Luigia, additional, Di Stefano, Michele, additional, Discepolo, Valentina, additional, Fasano, Alessio, additional, Francavilla, Ruggiero, additional, Gasbarrini, Antonio, additional, Gasbarrini, Giovanni, additional, Gatti, Simona, additional, Gianfrani, Carmen, additional, Giuliano, Alessandra, additional, Greco, Luigi, additional, Guandalini, Stefano, additional, Ianiro, Gianluca, additional, Lenti, Marco Vincenzo, additional, Lionetti, Elena, additional, Lucioni, Marco, additional, Maimaris, Stiliano, additional, Mamone, Gianfranco, additional, Mandile, Roberta, additional, Mansueto, Pasquale, additional, Marafini, Irene, additional, Mariotti, Elena Biancamaria, additional, Mengoli, Caterina, additional, Monteleone, Giovanni, additional, Monteleone, Ivan, additional, Neuhold, Susanna, additional, Novellino, Luisa, additional, Pilo, Caterina, additional, Plutino, Giuseppe, additional, Sansotta, Naire, additional, Santacroce, Giovanni, additional, Schiepatti, Annalisa, additional, Seidita, Aurelio, additional, Silano, Marco, additional, Troncone, Edoardo, additional, Troncone, Riccardo, additional, Vanoli, Alessandro, additional, Vitale, Serena, additional, Volta, Umberto, additional, Zanini, Annalisa, additional, and Zingone, Fabiana, additional

Published
2024
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5. Clinical and Pathological Features of Severe Gut Dysmotility

Author

Bianco, Francesca, Bonora, Elena, Lattanzio, Giulia, Clavenzani, Paolo, Guarino, Matteo, Mazzoni, Maurizio, Baldassarro, Vito Antonio, Lorenzini, Luca, Caio, Giacomo, Stanghellini, Vincenzo, Sternini, Catia, Farrugia, Gianrico, Giardino, Luciana, Calzà, Laura, De Giorgio, Roberto, Crusio, Wim E., Series Editor, Dong, Haidong, Series Editor, Radeke, Heinfried H., Series Editor, Rezaei, Nima, Series Editor, Steinlein, Ortrud, Series Editor, Xiao, Junjie, Series Editor, Spencer, Nick J., editor, Costa, Marcello, editor, and Brierley, Stuart M., editor

Published
2022
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9. Phenotype and Treatment Options for Mesenteric Lymph Node Cavitating Syndrome in Coeliac Disease: A Case Series and Literature Review.

Author

Marchetti, Federica, Raju, Suneil A., Nandi, Nicoletta, Shiha, Mohamed G., Cross, Simon S., Rea, Benjamin, Caio, Giacomo, and Sanders, David S.

Subjects
LITERATURE reviews, WEIGHT loss, LYMPH nodes, SURVIVAL rate, CACHEXIA
Abstract

Background: There is a paucity of data on mesenteric lymph node cavitation syndrome (MLNCS), a rare condition associated with coeliac disease (CD), characterized by central necrosis within enlarged mesenteric lymph nodes. The largest case series of MLNCS was completed in 1984, (n = 6) and a poor prognosis was identified. Methods: A case series of all patients was conducted with MLNCS treated at the UK NHS England National Centre for Refractory Coeliac Disease between 2000 and 2023. A further literature review was conducted using PubMed and Google Scholar for patients with MLNCS and coeliac disease until 2023. Results: In total, there were 51 patients (6 from our case series and 45 from the literature review); 57% were female, and the mean age was 52.8 years (SD: 14.01 years). The most common presenting symptoms were weight loss (80%) and diarrhea (65%), and patients often had hyposplenism (80%). Persistent villous atrophy was present in 88% of the patients. Ten patients also had Refractory Coeliac Disease. Most of the patients (90%) were on a GFD, but the effect of this is unclear. Treatment with steroids and immunosuppressants resulted in a 40% survival rate. The overall mortality was 43%, associated with cachexia, sepsis, infectious complications, and lymphoma. Conclusions: MLNCS has a poor prognosis, and its diagnosis should prompt further intervention and careful follow-up. Patients commonly present with weight loss and hyposplenism should prompt further investigation. Current treatment options are inadequate and novel therapies are required. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Resilience in Adult Coeliac Patients on a Gluten-Free Diet: A Cross-Sectional Multicentre Italian Study.

Author

Schiepatti, Annalisa, Maimaris, Stiliano, Randazzo, Simona, Maniero, Daria, Biti, Roland, Caio, Giacomo, Lungaro, Lisa, Carroccio, Antonio, Seidita, Aurelio, Scalvini, Davide, Ciacci, Carolina, Biagi, Federico, and Zingone, Fabiana

Abstract

Background. Data on resilience, the ability to recover from adversity, in coeliac disease (CeD) are lacking. Aim. To assess the degree of resilience in patients with CeD on a gluten-free diet (GFD), and its association with clinical features, sociodemographic factors, psychological morbidity, and quality of life (QOL). Methods. A cross-sectional multicentre Italian study was conducted on adult CeD patients between May 2022 and April 2023. Connor–Davidson Resilience Scale (CD-RISC), the Coeliac Disease-specific Quality of Life Scale (CD-QOL), the State–Trait Anxiety Inventory scale (STAI-Y), and the Beck Depression Inventory scale (BDI) were used to evaluate resilience, QOL, anxiety, and depression, respectively. A multivariate analysis was conducted to identify factors independently associated with the degree of resilience. Results. A total of 305 patients (221 F, mean age at CeD diagnosis 36 ± 16 years) on a long-term GFD (median 8 years, IQR 3–17) were enrolled. A total of 298/305 patients (98%) had a high level of resilience (CD-RISC ≥ 35). At univariate analysis, resilience was statistically associated with male gender (p = 0.03), age at enrolment (p = 0.02), marital status (p = 0.03), QOL (p < 0.001), anxiety (p < 0.001), and depression (p < 0.001). On multivariate regression analysis, trait anxiety (STAI-Y2, p < 0.001) and depression (BDI, p = 0.02) were independent predictors of lower levels of resilience. Conclusions. Higher trait anxiety predicts lower levels of resilience. Targeted interventions in this subgroup of patients may be helpful for their management and follow-up. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Celiac Disease: A Forty-Year Analysis in an Italian Referral Center.

Author

Lungaro, Lisa, Costanzini, Anna, Manza, Francesca, Caputo, Fabio, Remelli, Francesca, Volpato, Stefano, De Giorgio, Roberto, Volta, Umberto, and Caio, Giacomo

Abstract

Background: Celiac disease (CD) is an autoimmune disorder triggered by gluten ingestion. Herein, we assessed clinical, serological and histopathological findings of a single-center, large cohort of CD patients diagnosed and followed-up over forty years. Methods: From January 1980 to December 2020, 1547 CD patients (1170 females; age range: 8–81 years; F:M ratio = 3.1:1) were diagnosed in an Italian tertiary referral center. Comorbidities and complications were recorded at diagnosis and during follow-up. Results: CD diagnoses quadrupled after 2000. The most frequent phenotype was the non-classical CD (63.3%), and the most prevalent histotype was Marsh 3C (44.7%). Gastrointestinal manifestations, detectable in 51% of patients, were diarrhea (24.3%), bloating (28%) and aphthous stomatitis (19.7%). The most common CD-associated disorder was osteopenia (59.9%), predominant in females (64.3%); extraintestinal manifestations included anemia (35.8% iron-deficiency; 87% folic acid malabsorption), cryptogenic hypertransaminasemia (27.9%), and recurrent miscarriages (11.5%). Thyroiditis (26.9%), type 1 diabetes mellitus (2.9%), and dermatitis herpetiformis (1.4%) were the most common CD-related autoimmune disorders. Six patients had inflammatory bowel disease. Complications and mortality rate occurred in 1.8% and 1.9%, respectively. Conclusions: This single-center, large cohort analysis confirmed that CD presentation changed over the years, with an increase of non-classical and subclinical clinical phenotypes. [ABSTRACT FROM AUTHOR]

Published
2024
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14. PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability

Author

Giuffrida, Paolo, Arpa, Giovanni, Grillo, Federica, Klersy, Catherine, Sampietro, Gianluca, Ardizzone, Sandro, Fociani, Paolo, Fiocca, Roberto, Latella, Giovanni, Sessa, Fausto, D'Errico, Antonietta, Malvi, Deborah, Mescoli, Claudia, Rugge, Massimo, Nesi, Gabriella, Ferrero, Stefano, Furlan, Daniela, Poggioli, Gilberto, Rizzello, Fernando, Macciomei, Maria C., Santini, Donatella, Volta, Umberto, De Giorgio, Roberto, Caio, Giacomo, Calabrò, Antonio, Ciacci, Carolina, D'Armiento, Maria, Rizzo, Aroldo, Solina, Gaspare, Martino, Michele, Tonelli, Francesco, Villanacci, Vincenzo, Cannizzaro, Renato, Canzonieri, Vincenzo, Florena, Ada M., Biancone, Livia, Monteleone, Giovanni, Caronna, Roberto, Ciardi, Antonio, Elli, Luca, Caprioli, Flavio, Vecchi, Maurizio, D'Incà, Renata, Zingone, Fabiana, D'Odorico, Anna, Lenti, Marco Vincenzo, Oreggia, Barbara, Reggiani Bonetti, Luca, Astegiano, Marco, Biletta, Elena, Cantoro, Laura, Giannone, Antonino G., Orlandi, Augusto, Papi, Claudio, Perfetti, Vittorio, Quaquarini, Erica, Sandri, Giancarlo, Silano, Marco, Usai, Paolo, Barresi, Valeria, Ciccocioppo, Rachele, Luinetti, Ombretta, Pedrazzoli, Paolo, Pietrabissa, Andrea, Viglio, Alessandra, Paulli, Marco, Corazza, Gino R., Solcia, Enrico, Vanoli, Alessandro, and Di Sabatino, Antonio

Published
2020
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17. Prognostic Role of Mismatch Repair Status, Histotype and High-Risk Pathologic Features in Stage II Small Bowel Adenocarcinomas

Author

Vanoli, Alessandro, Grillo, Federica, Guerini, Camilla, Neri, Giuseppe, Arpa, Giovanni, Klersy, Catherine, Nesi, Gabriella, Giuffrida, Paolo, Sampietro, Gianluca, Ardizzone, Sandro, Fociani, Paolo, Fiocca, Roberto, Latella, Giovanni, Sessa, Fausto, D’Errico, Antonietta, Malvi, Deborah, Mescoli, Claudia, Rugge, Massimo, Ferrero, Stefano, Poggioli, Gilberto, Rizzello, Fernando, Macciomei, Maria C., Santini, Donatella, Volta, Umberto, De Giorgio, Roberto, Caio, Giacomo, Calabrò, Antonio, Ciacci, Carolina, D’Armiento, Maria, Rizzo, Aroldo, Solina, Gaspare, Martino, Michele, Tonelli, Francesco, Villanacci, Vincenzo, Cannizzaro, Renato, Canzonieri, Vincenzo, Florena, Ada Maria, Biancone, Livia, Monteleone, Giovanni, Caronna, Roberto, Ciardi, Antonio, Elli, Luca, Caprioli, Flavio, Vecchi, Maurizio, D’Incà, Renata, Zingone, Fabiana, D’Odorico, Anna, Lenti, Marco Vincenzo, Oreggia, Barbara, Reggiani Bonetti, Luca, Giannone, Antonino Giulio, Orlandi, Augusto, Barresi, Valeria, Ciccocioppo, Rachele, Amodeo, Giuseppe, Biletta, Elena, Luinetti, Ombretta, Pedrazzoli, Paolo, Pietrabissa, Andrea, Corazza, Gino Roberto, Solcia, Enrico, Paulli, Marco, and Di Sabatino, Antonio

Published
2021
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21. Paraneoplastic Syndrome

Author

Ursini, Francesco, primary, Caio, Giacomo, additional, Volta, Umberto, additional, Manfredini, Roberto, additional, and De Giorgio, Roberto, additional

Published
2020
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26. Chronic constipation in Parkinson's disease: clinical features and molecular insights on the intestinal epithelial barrier.

Author

Ioannou, Alexandros, Costanzini, Anna, Giancola, Fiorella, Cabanillas, Luis, Lungaro, Lisa, Manza, Francesca, Guarino, Matteo, Arena, Rosario, Caio, Giacomo, Torresan, Francesco, Polydorou, Andreas, Vezakis, Antonios, Karamanolis, George, Sternini, Catia, and De Giorgio, Roberto

Subjects
PARKINSON'S disease, ENTERIC nervous system, VASOACTIVE intestinal peptide, CONSTIPATION, INTESTINES
Abstract

Background Chronic constipation (CC) is a severe symptom in Parkinson's disease (PD), with an unclear pathogenesis. Abnormalities of the enteric nervous system (ENS) and/or intestinal epithelial barrier (IEB) may be pathophysiologically relevant in PD patients with CC. We investigated possible molecular changes of the IEB in PD/CCs compared with CCs and controls. Methods Twelve PD/CCs (2 female, age range 51-80 years), 20 CCs (15 female, age range 27-78 years), and 23 controls (11 female, age range 32-74 years) were enrolled. Ten PD/CCs and 10 CCs were functionally characterized by anorectal manometry (AM) and transit time (TT). Colon biopsies were obtained and assessed for gene and protein expression, and localization of IEB tight junction markers claudin-4 (CLDN4), occludin-1 (OCCL-1), and zonula occludens-1 (ZO-1) by RT-qPCR, immunoblot and immunofluorescence labeling. Results PD/CCs were clustered in 2 functional categories: patients with delayed TT and altered AM (60%), and a second group showing only modifications in AM pattern (40%). Gene expression of CLDN4, OCCL-1 and ZO-1 was higher in PD/CCs than controls (P<0.05). Conversely, PD/CCs showed a trend to decrease (P>0.05) in CLDN4 and OCCL-1 protein levels than controls, whereas ZO-1 protein was comparable. In PD/CCs compared with controls, decreasing tendency of vasoactive intestinal polypeptide mRNA, protein and immunoreactive fiber density were observed, although the difference was not statistically significant. Conclusion Transit and anorectal dysfunctions in PD/CCs are associated with difference in ZO-1, OCCL-1 and CLDN4 expression, thus supporting the role of an altered IEB as a contributory mechanism to possible neuronal abnormalities. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Osteoporosis and Celiac Disease: Updates and Hidden Pitfalls

Author

Lungaro, Lisa, primary, Manza, Francesca, additional, Costanzini, Anna, additional, Barbalinardo, Marianna, additional, Gentili, Denis, additional, Caputo, Fabio, additional, Guarino, Matteo, additional, Zoli, Giorgio, additional, Volta, Umberto, additional, De Giorgio, Roberto, additional, and Caio, Giacomo, additional

Published
2023
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39. Correction: PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability

Author

Giuffrida, Paolo, Arpa, Giovanni, Grillo, Federica, Klersy, Catherine, Sampietro, Gianluca, Ardizzone, Sandro, Fociani, Paolo, Fiocca, Roberto, Latella, Giovanni, Sessa, Fausto, D’Errico, Antonietta, Malvi, Deborah, Mescoli, Claudia, Rugge, Massimo, Nesi, Gabriella, Ferrero, Stefano, Furlan, Daniela, Poggioli, Gilberto, Rizzello, Fernando, Macciomei, Maria C., Santini, Donatella, Volta, Umberto, De Giorgio, Roberto, Caio, Giacomo, Calabrò, Antonio, Ciacci, Carolina, D’Armiento, Maria, Rizzo, Aroldo, Solina, Gaspare, Martino, Michele, Tonelli, Francesco, Villanacci, Vincenzo, Cannizzaro, Renato, Canzonieri, Vincenzo, Florena, Ada M., Biancone, Livia, Monteleone, Giovanni, Caronna, Roberto, Ciardi, Antonio, Elli, Luca, Caprioli, Flavio, Vecchi, Maurizio, D’Incà, Renata, Zingone, Fabiana, D’Odorico, Anna, Lenti, Marco Vincenzo, Oreggia, Barbara, Bonetti, Luca Reggiani, Astegiano, Marco, Biletta, Elena, Cantoro, Laura, Giannone, Antonino G., Orlandi, Augusto, Papi, Claudio, Perfetti, Vittorio, Quaquarini, Erica, Sandri, Giancarlo, Silano, Marco, Usai, Paolo, Barresi, Valeria, Ciccocioppo, Rachele, Luinetti, Ombretta, Pedrazzoli, Paolo, Pietrabissa, Andrea, Viglio, Alessandra, Paulli, Marco, Corazza, Gino R., Solcia, Enrico, Vanoli, Alessandro, and Di Sabatino, Antonio

Published
2020
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40. Guidelines of the Italian societies of gastroenterology on the diagnosis and management of coeliac disease and dermatitis herpetiformis

Author

Zingone, Fabiana, primary, Maimaris, Stiliano, additional, Auricchio, Renata, additional, Caio, Giacomo Pietro Ismaele, additional, Carroccio, Antonio, additional, Elli, Luca, additional, Galliani, Ermenegildo, additional, Montagnani, Marco, additional, Valiante, Flavio, additional, and Biagi, Federico, additional

Published
2022
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41. Beyond biologics: advanced therapies in inflammatory bowel diseases

Author

CAIO, Giacomo, primary, LUNGARO, Lisa, additional, CHIARIONI, Giuseppe, additional, GIANCOLA, Fiorella, additional, CAPUTO, Fabio, additional, GUARINO, Matteo, additional, VOLTA, Umberto, additional, TESTINO, Gianni, additional, PELLICANO, Rinaldo, additional, ZOLI, Giorgio, additional, and DE GIORGIO, Roberto, additional

Published
2022
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43. Anemia in non-celiac wheat sensitivity: Prevalence and associated clinical and laboratory features.

Author

Mansueto, Pasquale, Seidita, Aurelio, Soresi, Maurizio, Giuliano, Alessandra, Riccio, Giorgia, Volta, Umberto, Caio, Giacomo, La Blasca, Francesco, Disclafani, Rosaria, De Giorgio, Roberto, and Carroccio, Antonio

Abstract

Patients suffering from non-celiac wheat sensitivity (NCWS) frequently report extra-intestinal symptoms, such as anemia. We investigated the prevalence and associated clinical features of anemia in NCWS patients. Data from 244 NCWS patients, diagnosed by double-blind placebo-controlled wheat challenge, were retrospectively reviewed and compared with 2 control groups (celiac disease (CD) and irritable bowel syndrome (IBS)). Furthermore, 31 NCWS anemic patients were prospectively re-evaluated after at least 12 months on the "strict" wheat-free diet (WFD). Anemia prevalence in NCWS patients was 34.8% (mean hemoglobin 10.4 ± 1.4 g/dl), significantly higher than in IBS (17.4%, P = 0.03), but not in CD ones. The NCWS group, on the whole, had sideropenic-like features with low serum iron and altered iron deposits. Both anemia prevalence and sideropenic-like features were more evident in CD than in NCWS patients, whereas only a few IBS subjects showed such features. Significant differences were found in anemic vs non-anemic NCWS patients as regards to female sex, diagnostic delay, poly/hypermenorrhea, iron deficiency, and higher TSH values. A long-term WFD significantly reduced anemia and improved iron metabolism. Microcytic/hypochromic anemia and altered iron metabolism occur frequently in NCWS and can be treated with a long-term strict WFD. NCWS should be included in differential diagnosis of anemic patients with "functional gastrointestinal troubles". [ABSTRACT FROM AUTHOR]

Published
2023
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44. Role of Intracellular Pulmonary Pathogens during SARS-CoV-2 Infection in the First Pandemic Wave of COVID-19: Clinical and Prognostic Significance in a Case Series of 1200 Patients

Author

Guarino, Matteo, primary, Perna, Benedetta, additional, Cuoghi, Francesca, additional, Spampinato, Michele Domenico, additional, Cesaro, Alice Eleonora, additional, Manza, Francesca, additional, Pretula, Adriana, additional, Grilli, Anastasio, additional, Maritati, Martina, additional, Caio, Giacomo, additional, Carnevale, Aldo, additional, Flacco, Maria Elena, additional, De Giorgio, Roberto, additional, and Contini, Carlo, additional

Published
2022
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45. Osteoporosis in Celiac Disease: An Update

Author

Lungaro, Lisa, primary, Manza, Francesca, additional, Costanzini, Anna, additional, caputo, fabio, additional, Zoli, Giorgio, additional, Volta, Umberto, additional, De Giorgio, Roberto, additional, and Caio, Giacomo, additional

Published
2022
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46. Nomenclature and diagnosis of seronegative coeliac disease and chronic non-coeliac enteropathies in adults: the Paris consensus

Author

Schiepatti, Annalisa, primary, Sanders, David S, additional, Baiardi, Paola, additional, Caio, Giacomo, additional, Ciacci, Carolina, additional, Kaukinen, Katri, additional, Lebwohl, Benjamin, additional, Leffler, Daniel, additional, Malamut, Georgia, additional, Murray, Joseph A, additional, Rostami, Kamran, additional, Rubio-Tapia, Alberto, additional, Volta, Umberto, additional, and Biagi, Federico, additional

Published
2022
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47. Efficacy and safety of capsule endoscopy in octogenarian patients: a retrospective study

Author

PEZZOLI, Alessandro, primary, GUARINO, Matteo, additional, FUSETTI, Nadia, additional, PIZZO, Elena, additional, SIMONI, Marzia, additional, SIMONE, Loredana, additional, CIFALÀ, Viviana, additional, SOLIMANDO, Riccardo, additional, PERNA, Benedetta, additional, TESTINO, Gianni, additional, CAIO, Giacomo, additional, LUNGARO, Lisa, additional, CAPUTO, Fabio, additional, ZOLI, Giorgio, additional, MERIGHI, Alberto, additional, and DE GIORGIO, Roberto, additional

Published
2022
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50. Su1885 THE IMPACT OF UNNECESSARY GLUTEN-FREE DIET ON GUT MICROBIOTA

Author

Manza, Francesca, Lungaro, Lisa, Costanzini, Anna, Segata, Nicola, Pinto, Federica, Puncochar, Michal, Asnicar, Francesco, Armanini, Federica, Carroccio, Antonio, Seidita, Aurelio, Mansueto, Pasquale, Calabrò, Antonino S., Cavalieri, Duccio, Barbara, Giovanni, Stanghellini, Vincenzo, Volta, Umberto, De Giorgio, Roberto, and Caio, Giacomo Pietro Ismaele

Published
2024
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