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Your search keyword '"Cajusma, Youseline"' showing total 14 results
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14 results on '"Cajusma, Youseline"'

1. Population-Based Serologic Survey of Vibrio cholerae Antibody Titers before Cholera Outbreak, Haiti, 2022

Author

Clutter, Christy H., Klarman, Molly B., Cajusma, Youseline, Cato, Emilee T., Sayeed, Md. Abu, Brinkley, Lindsey, Jensen, Owen, Baril, Chantale, De Rochars, V. Madsen Beau, Azman, Andrew S., Long, Maureen T., Cummings, Derek, Leung, Daniel T., and Nelson, Eric J.

Subjects
Prevention, Analysis, Risk factors, Dosage and administration, Cholera -- Risk factors -- Prevention, B cells -- Analysis, Demographic surveys -- Analysis, Cholera vaccines -- Dosage and administration, Cholera toxin -- Analysis
Abstract

In October 2010, a United Nations peacekeeping mission to Haiti following a highly destructive earthquake inadvertently introduced cholera (1,2), leading to [approximately equal to] 820,000 cases and [approximately equal to] [...]

Published
2023
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4. Development and evaluation of a clinical guideline for a paediatric telemedicine service in a low-resource setting

Author

Klarman, Molly B, primary, Chi, Xiaofei, additional, Cajusma, Youseline, additional, Flaherty, Katelyn E, additional, Capois, Anne Carine, additional, Dofiné, Michel Daryl Vladimir, additional, Exantus, Lerby, additional, Friesen, Jason, additional, Beau de Rochars, Valery Madsen, additional, Becker, Torben, additional, Baril, Chantale, additional, Gurka, Matthew J, additional, and Nelson, Eric J, additional

Published
2024
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5. Development and Evaluation of a Clinical Guideline for a Pediatric Telemedicine and Medication Delivery Service: A Prospective Cohort Study in Haiti

Author

Klarman, Molly B, primary, Chi, Xiaofei, additional, Cajusma, Youseline, additional, Flaherty, Katelyn E, additional, Capois, Anne Carine, additional, Vladimir Dofiné, Michel Daryl, additional, Exantus, Lerby, additional, Friesen, Jason, additional, Beau de Rochars, Valery M, additional, Becker, Torben K, additional, Baril, Chantale, additional, Gurka, Matthew J, additional, and Nelson, Eric J, additional

Published
2023
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6. A population-based serological survey ofVibrio choleraeantibody titers in Ouest Department, Haiti in the year prior to the 2022 cholera outbreak

Author

Clutter, Christy H., primary, Klarman, Molly B., additional, Cajusma, Youseline, additional, Cato, Emilie T., additional, Sayeed, Md. Abu, additional, Brinkley, Lindsey, additional, Jensen, Owen, additional, Baril, Chantale, additional, Beau De Rochars, V. Madsen, additional, Azman, Andrew S., additional, Long, Maureen T., additional, Cummings, Derek, additional, Leung, Daniel T., additional, and Nelson, Eric J., additional

Published
2023
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7. Implementation of a pediatric telemedicine and medication delivery service in a resource-limited setting: A pilot study for clinical safety and feasibility

Author

Klarman, Molly B., primary, Flaherty, Katelyn E., additional, Chi, Xiaofei, additional, Cajusma, Youseline, additional, Capois, Anne Carine, additional, Vladimir Dofiné, Michel Daryl, additional, Exantus, Lerby, additional, Friesen, Jason, additional, Beau de Rochars, Valery M., additional, Baril, Chantale, additional, Gurka, Matthew J., additional, Becker, Torben K., additional, and Nelson, Eric J., additional

Published
2022
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14. A population-based serological survey of Vibrio cholerae antibody titers in Ouest Department, Haiti in the year prior to the 2022 cholera outbreak.

Author

Clutter CH, Klarman MB, Cajusma Y, Cato ET, Sayeed A, Brinkley L, Jensen O, Baril C, De Rochars VMB, Azman AS, Long MT, Cummings D, Leung DT, and Nelson EJ

Abstract

After three years with no confirmed cholera cases in Haiti, an outbreak of Vibrio cholerae O1 emerged in October 2022. Levels of pre-existing antibodies provide an estimate of prior immunologic exposure, reveal potentially relevant immune responses, and set a baseline for future serosurveillance. We analyzed dried blood spots collected in 2021 from a population-weighted representative cross-sectional serosurvey in two communes in the Ouest Department of Haiti. We found lower levels of circulating IgG and IgA antibodies against V. cholerae lipopolysaccharide (LPS, IgG and IgA p<0.0001) in those below 5 years of age compared to those five years and older. Among a subset of patients with higher titers of antibodies, we were unable to detect any functional (vibriocidal) antibodies. In conclusion, the lack of detectable functional antibodies, and age-discordant levels of V. cholerae LPS IgG, suggest that populations in Haiti may be highly susceptible to cholera disease, especially among young children., Competing Interests: Conflict of Interest Disclosures. The authors declare that they have no competing interests.

Published
2023
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