138 results on '"Calado, Ana"'
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2. Subcutaneous Indurated Plaques in a Newborn
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Calado, Ana Rebeca Neves, Martins, Ana Isabel Barros Ramos, Dionísio, Maria Teresa, Morgado, Maria Francisca Jacome, Ramos, Leonor Isabel Castendo, Figueiredo, Américo Manuel Costa, Norman, Robert A., Series Editor, Arcangeli, Fabio, editor, and Lotti, Torello M., editor
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- 2022
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3. Subcutaneous Indurated Plaques in a Newborn
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Calado, Ana Rebeca Neves, primary, Martins, Ana Isabel Barros Ramos, additional, Dionísio, Maria Teresa, additional, Morgado, Maria Francisca Jacome, additional, Ramos, Leonor Isabel Castendo, additional, and Figueiredo, Américo Manuel Costa, additional
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- 2022
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4. HISTÓRIA DO ENSINO DE HISTOLOGIA E DE PATOLOGIA
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Calado, Ana Margarida, primary
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- 2021
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5. Ultrastructural Changes in Candida albicans Induced by Benzyl Isothiocyanate (BITC)
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Calado, Ana, primary, Pereira, Cheila, additional, and Sampaio, Ana C., additional
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- 2023
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6. The effect of benzyl isothiocyanate on Candida albicans growth, cell size, morphogenesis, and ultrastructure
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Pereira, Cheila, Calado, Ana Margarida, and Sampaio, Ana Cristina
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- 2020
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7. sQuiz your Knowledge! Multiple pigmented macules following Langer lines
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Das Neves Calado, Ana Rebeca, Pereira, Ana Sofia, and Castendo Ramos, Leonor Isabel
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- 2021
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8. O diferencial do acadêmico inserido na vivência do pet saúde: relato de experiência dos monitores
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Calado, Ana Beatriz De Melo, primary, Pinto, Artur Duarte, additional, Silva, Quitéria Maria Ferreira da, additional, Santos, Thayná Patrícia Almeida, additional, Silva, Raphaela Victoria Gomes da, additional, Alves, Maria Izabel de Mendonça, additional, Rosa, Marina de Oliveira, additional, Oliveira, Ana Luiza de Andrade Melo, additional, Oliveira, Iranir de, additional, and Prado, Érika Rosângela Alves, additional
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- 2023
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9. All that glitters is not gold: a stereological study of human donor oocytes – CORRIGENDUM
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Santos, Tânia, primary, Pires-Luís, Ana S., additional, Alves, Ângela, additional, Oliveira, Elsa, additional, Leal, Carla, additional, Fernandes, Mónica, additional, Vale-Fernandes, Emídio, additional, Barreiro, Márcia, additional, Calado, Ana-Margarida, additional, Sá, Rosália, additional, and Sousa, Mário, additional
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- 2023
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10. A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review.
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Martins de Oliveira, Paula Alexandra, Faustino-Rocha, Ana I., Gil da Costa, Rui M., Nascimento Gonçalves, Elisabete, Margarida Calado, Ana, Jota Baptista, Catarina, Gama, Adelina, and Seixas, Fernanda
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LITERATURE reviews ,TERATOMA ,MICE ,NERVE tissue ,ABDOMEN ,SEBACEOUS glands - Abstract
Background: Teratomas are rare types of germ cell neoplasms composed of various differentiated or undifferentiated tissues. Case Description: A 25-week-old female control FVB /n mouse in a 4-week toxicity study presented abdominal distension and poor body condition. It was euthanized, and the necropsy examination revealed a large mass connected to the tip of the right uterine horn, occupying the entire abdominal cavity. Microscopically, this mass showed areas of epidermal differentiation, with laminated keratin and sebaceous glands, differentiation into respiratory and digestive epithelium, cartilage, bone, and extensive areas of differentiation into the nervous tissue, being classified as an ovarian teratoma. Conclusion: As far as authors know, the occurrence of ovarian teratomas in the FVB/n mouse strain has never been previously described. [ABSTRACT FROM AUTHOR]
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- 2023
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11. Spatial Distribution of SARS-CoV-2 Receptors and Proteases in Testicular Cells
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Ribeiro, Maria Rita, primary, Calado, Ana Margarida, additional, Alves, Ângela, additional, Pereira, Rute, additional, Sousa, Mário, additional, and Sá, Rosália, additional
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- 2023
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12. Matrix solution for the inverse problem of classical dynamics of a particle
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B. Calado, Ana, primary and D. Bulnes, Juan, additional
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- 2023
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13. SÍNDROME PÓS-COVID-19: SCOPING REVIEW
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Ferreira, Carine Vitória Lemes, Fontenele, Esther Sampaio, Oliveira, Darlene Andrade, Daislaine De Jesus Lima, Kellyanne Pessoa Lima, Carvalho, Maria Ramonielly Feitosa Rodrigues, Conceição, Mirian Santos Silva, Santos, Alexandre Gois Dos, Milene Dos Santos Basilio De Oliveira, Gleison Lucas Santos Do Nascimento, De Oliveira Subrinho, Douglas, Elder Santos Freiras, De Melo Calado, Ana Beatriz, Rosário, Gabriele Lopes Do, Érica Motta Moreira De Souza, and Pires, Carlos Henrique Nunes
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Síndrome Pós-COVID-19 Aguda ,COVID de Longo Curso ,Síndrome de Fadiga Crônica/ Encefalomielite Miálgica ,Acute Post-COVID-19 Syndrome ,Long Haul COVID ,Chronic Fatigue Syndrome/Myalgic Encephalomyelitis - Abstract
Introdução:A síndrome respiratória aguda grave coronavírus 2 além de causar a doença aguda de COVID-19, após a recuperação pode deixar sintomas persistentes, ou seja, a síndrome pós-COVID-19 (PCS), também conhecida como longo COVID-19, comumente usados para descrever sintomas crônicos da infecção por SARS-CoV-2. A PCS é definida como a persistência dos sintomas por mais de 12 semanas após a infecção pelo vírus.Objetivo:Tem-se como objetivo deste estudo identificar os principais sintomas crônicos de longo prazo do COVID-19 que persistem por meses após a infecção. Além disso, busca-se entender a semelhança da PCS com a ME/CFS.Metodologia:Trata-se de um estudo de Scoping Review, de acordo com a metodologia de revisão proposto pelo Instituto Joanna Briggs. A amostra final totalizou em 08 estudos selecionados. A revisão de escopo foi realizada a partir das seguintes questões de pesquisa: Quais são os principais sintomas crônicos adquiridos após infecção por COVID-19? Está realmente associado com a síndrome da fadiga crônica/encefalomielite miálgica?Resultados:Identificaram-se que não há uma diferença significativa nas características clínicas/inflamatórias entre a PCS e ME/CFS. Entre os principais sintomas incluem fadiga, mal-estar pós-esforço, comprometimento cognitivo, distúrbios do sono, tontura, dor e alterações de humor em ambos os grupos. Evidenciou-se também que a duração média dos sintomas após COVID-19 foi maior na presença de outras comorbidades prévia à infecção. São mais frequentes em mulheres do que em homens. Conclusão:Destarte, esta revisão de escopo respondeu ao longo da pesquisa as questões norteadoras supracitadas. A persistência de sintomas de longo prazo em alguns pacientes com COVID-19 abriu uma nova linha de pesquisa sobre os mecanismos subjacentes à ME/CFS. Esta revisão avalia a qualidade dos estudos de maneira minuciosa e fornece informações valiosas sobre as evidências.
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- 2023
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14. Spontaneous Zymbal's gland tumor in a 25-week old Wistar male rat: a case report.
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Faustino-Rocha, Ana I., Oliveira, Paula A., Calado, Ana. M., and Seixas, Fernarda
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Copyright of Veterinarska Stanica is the property of Croatian Veterinary Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2025
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15. Artificial neural network modelling of the chemical composition of carrots submitted to different pre-drying treatments
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Barroca, Maria João, Guiné, Raquel P. F., Calado, Ana Rita P., Correia, Paula M. R., and Mendes, Mateus
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- 2017
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16. A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review
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Oliveira, Paula, primary, Rocha, Ana, additional, Costa, Rui, additional, alves, Elisabete, additional, Calado, Ana, additional, Baptista, Catarina, additional, Gama, Adelina, additional, and Seixas, Fernanda, additional
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- 2023
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17. An Overview of Teratology
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Calado, Ana M., primary and dos Anjos Pires, Maria, additional
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- 2018
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18. Parvovirus B19 infection associated with hemolytic anemia and cranial polyneuropathy
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Sequeira, João, Calado, Ana, Dias, Margarida, and Manita, Manuel
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- 2017
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19. História da Teratologia
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Calado, Ana Margarida, primary
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- 2022
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20. Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP
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Guerreiro, Rita Joao, Baquero, Miquel, Blesa, Rafael, Boada, Mercè, Brás, Jose Miguel, Bullido, Maria J., Calado, Ana, Crook, Richard, Ferreira, Carla, Frank, Ana, Gómez-Isla, Teresa, Hernández, Isabel, Lleó, Alberto, Machado, Alvaro, Martínez-Lage, Pablo, Masdeu, José, Molina-Porcel, Laura, Molinuevo, José L., Pastor, Pau, Pérez-Tur, Jordi, Relvas, Rute, Oliveira, Catarina Resende, Ribeiro, Maria Helena, Rogaeva, Ekaterina, Sa, Alfredo, Samaranch, Lluís, Sánchez-Valle, Raquel, Santana, Isabel, Tàrraga, Lluís, Valdivieso, Fernando, Singleton, Andrew, Hardy, John, and Clarimón, Jordi
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- 2010
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21. Treinamento motor em indivíduos com doença de Parkinson // Motor training in individuals with Parkinson's disease
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Clementino, Adriana Carla Costa Ribeiro, primary, De Menezes, David Sam Pessoa, additional, Guimarães, Dayane Géssica Gomes, additional, Fernandes, Gabriella Nascimento, additional, Da Silva, Arielson Santos Alves, additional, De Menezes, Débora Maggy Pessoa, additional, De Oliveira, Erick Barbosa Sousa, additional, Da Silva, Gabriel Nogueira, additional, Calado, Ana Carolina de Lima, additional, Dos Santos, Andreza Crislane, additional, and Da Silva, Aline Maria Monteiro, additional
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- 2022
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22. Clinical and genetic characteristics of late-onset Huntington's disease
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Oosterloo, Mayke, Bijlsma, Emilia K., van Kuijk, Sander MJ., Minkels, Floor, de Die-Smulders, Christine EM., Bachoud-Lévi, Anne-Catherine, Bentivoglio, Anna-Rita, Biunno, Ida, Bonelli, Raphael M., Bronzova, Juliana, Burgunder, Jean-Marc, Dunnett, Stephen B., Ferreira, Joaquim J., Frich, Jan, Giuliano, Joe, Handley, Olivia J., Heiberg, Arvid, Illarioshkin, Sergey, Illmann, Torsten, Klempir, Jiri, Landwehrmeyer, G. Bernhard, Levey, Jamie, Mclean, Tim, Nielsen, Jørgen E., Koivisto, Susana Pro, Päivärinta, Markku, Pålhagen, Sven, Quarrell, Oliver, Ramos-Arroyo, Maria, Roos, Raymund A. C., Saft, Carsten, Sebastián, Ana Rojo, Tabrizi, Sarah J., Vandenberghe, Wim, Verellen-Dumoulin, Christine, Uhrova, Tereza, Wahlström+, Jan, Zaremba, Jacek (formerly Rödig, Verena, Baake, Barth, Katrin, Garde, Monica Bascuñana, Becanovic, Kristina, Bernard, Tomáš, Betz, Sabrina, Bos, Reineke, Come, Adrien, Guedes, Leonor Correia, Callaghan, Jenny, Capodarca, Selene, Charpentier, Sébastien, Vieira da Silva, Wildson, Di Renzo, Martina, Ecker, Daniel, Finisterra, Ana Maria, Fullam, Ruth, Genoves, Camille, Gilling, Mette, Horta, Andrea, Hvalstedt, Carina, Held, Christine, Hussain, Hasina, Koppers, Kerstin, Lamanna, Claudia, Laurà, Matilde, Descals, Asunción Martínez, Martinez-Horta, Saul, Mestre, Tiago, Minster, Sara, Monza, Daniela, Münkel, Kristina, Mütze, Lisanne, Oehmen, Martin, Padieu, Helene, Paterski, Laurent, Peppa, Nadia, Rindal, Beate, Rogers, Dawn, Røren (formerly Heinonen), Niini, Salgueiro, Ana, Šašinková, Pavla, Seliverstov, Yury, Taylor, Catherine, Timewell, Erika, Townhill, Jenny, Cubillo, Patricia Trigo, van Walsem, Marleen R., Witjes-Ané, Marie-Noelle, Witkowski, Grzegorz, Wright, Abigail, Yudina, Elizaveta, Zielonka, Daniel, Zielonka, Eugeniusz, Zinzi, Paola, Hecht, Karen, Herranhof, Brigitte, Holl (formerly Hödl), Anna, Kapfhammer, Hans-Peter, Koppitz, Michael, Lilek, Sabine, Magnet, Markus, Müller, Nicole, Otti, Daniela, Painold, Annamaria, Reisinger, Karin, Scheibl, Monika, Schöggl, Helmut, Ullah, Jasmin, Braunwarth, Eva-Maria, Brugger, Florian, Buratti, Lisa, Hametner, Eva-Maria, Hepperger, Caroline, Holas, Christiane, Hotter, Anna, Hussl, Anna, Larcher, Barbara, Mahlknecht, Philipp, Müller, Christoph, Pinter, Bernadette, Poewe, Werner, Reiter, Eva-Magdalena, Seppi, Klaus, Sprenger, Fabienne, Wenning, Gregor, Ladurner, Gunther, Lilek, Stefan, Sinadinosa, Daniela, Staffen, Wolfgang, Walleczek, Anna Maria, Linder, Christoph, Pirker, Walter, Liessens, Dirk, Calmeyn, Godelinde, Somers, Nele, Delvaux, Isabelle, Boogaerts, Andrea, Flamez, Anja, de Raedt, Sylvie, Alaerts, Nick, Slama, Hichem, Supiot, Frédéric, Constant, Eric, Gillardin, Anne-Françoise, Léonard, Marie-Claude, van de Wyngaerde, Françoise, Dupuis, Michel, Minet, Cécile, Ribaï, Pascale, Van Paemel, Dominique, van Reijen, Dimphna, Weckx, Petra, Kaiserova, Michaela, Šenkárová, Zuzana, Bezdíček, Ondřej, Klempíř, Jiří, Klempířová, Olga, Majerová-Ibarburu, Veronika, Nikolai, Tomáš, Roth, Jan, Stárková, Irena, Madsen, Louise Hasselstrøm, Møller, Anette Torvin, Hjermind, Lena, Jacobsen, Oda, Larsen, Ida Unmack, Lindquist, Suzanne, Nielsen, Jørgen, Regeur, Lisbeth, Roos, Peter, Stockholm, Jette, Vangsted-Hansen, Christina, Vinther-Jensen, Tua, Lolk, Annette, Lundsgaard, Marianne, Wermuth, Lene, Andersson, Christian, Nyberg, Clara, Sundblom, Jimmy, Peippo, Maarit, Sipponen, Marjatta, Bruun, Anu, Hartikainen, Paivi, Mäkipää, Seija, Ollokainen, Mari, Åman, Jaana, Kärppä, Mikko, Ignatius, Jaakko, Jääskeläinen, Outi, Kajula, Outi, Moilanen, Jukka, Mustonen, Aki, Santala, Maire, Eklund, Pia, Hiivola, Heli, Hyppönen, Hannele, Martikainen, Kirsti, Ojala, Marjut, Tähkäpää, Sirkku, Tuuha, Katri, Allain, Philippe, Bonneau, Dominique, Bost, Marie, Gohier, Bénédicte, Guérid, Marie-Anne, Olivier, Audrey, Prouzet, Julie, Prundean, Adriana, Scherer-Gagou, Clarisse, Verny, Christophe, Babiloni, Blandine, Bled, Déborah, Debruxelles, Sabrina, Duché, Charlotte, Fraisse, Sonia, Goizet, Cyril, Jameau, Laetitia, Lafoucrière, Danielle, Spampinato, Umberto, Couttier, Julien, Debilly, Bérengère, Delaigue, Christine, Derost, Philippe, Durif, Franck, Germain, Véronique, Legendre, Perrine, Loiseau, Sylvie, Marques, Ana, Ulla, Miguel, Vidal, Tiphaine, Badei, Farideh, Boissé, Marie-Françoise, Boudali, Lotfi, Cleret de Langavant, Laurent, Lemoine, Laurie, Morgado, Graca, Youssov, Katia, Annic, Agnès, Barthélémy, Recka, De Bruycker, Christelle, Cabaret, Maryline, Carette, Anne-Sophie, Carrière, Nicolas, Decorte, Eric, Defebvre, Luc, Delliaux, Marie, Delval, Arnaud, Depelchin, Alizé, Destee, Alain, Dewulf-Pasz, Nelly, Dondaine, Thibaut, Dugauquier, Florence, Dujardin, Kathy, Hopes, Lucie, Krystkowiak, Pierre, Lemaire, Marie-Hélène, Manouvrier, Sylvie, Mutez, Eugénie, Peter, Mireille, Plomhause, Lucie, Sablonnière, Bernard, Simonin, Clémence, Tard, Céline, Thibault-Tanchou, Stéphanie, Vuillaume, Isabelle, Bellonet, Marcellin, Blin, Stéphanie, Chen, Simone, Masmoudi, Kamel, Morin, Gilles, Roussel, Martine, Tir, Mélissa, Schüler, Béatrice, Wannepain, Sandrine, Zouitina, Yassine, Azulay, Jean-Philippe, Delfini, Marie, Eusebio, Alexandre, Fluchere, Frédérique, Guenam, Aicha, Mundler, Laura, Nguyen, Karine, Benaich, Sandra, Brice, Alexis, Boster, Sarah, Charles, Perrine, Durr, Alexandra, Ewenczyk, Claire, Francisque, Hélène, Jauffret, Céline, Justo, Damian, Kassar, Abdulrahman, Klebe, Stephan, Lesne, Fabien, Milani, Paolo, Monin, Marie-Lorraine, Monnier, Tiffany, Roze, Emmanuel, Tataru, Alina, Tchikviladzé, Maya, Bioux, Sandrine, Bliaux, Evangeline, Girard, Carole, Guyant-Maréchal, Lucie, Hannequin, Didier, Hannier, Véronique, Jourdain, Séverine, Maltête, David, Pouliquen, Dorothée, Anheim, Mathieu, Barun, Nadia, Lagha-Boukbiza, Ouhaid, Longato, Nadine, Marcel, Christophe, Phillipps, Clélie, Rudolf, Gabrielle, Steinmetz, Gisèle, Tranchant, Christine, Wagner, Caroline, Zimmermann, Marie-Agathe, Blondeau, Leily, Calvas, Fabienne, Cheriet, Samia, Delabaere, Helène, Demonet, Jean-François, Marquine, Laurent, Pariente, Jérémie, Pierre, Michèle, Pomies, Elsa, Rolland, Sandrine, Souyris, Corinne, Kosinski, Christoph Michael, Milkereit, Eva, Probst, Daniela, Reetz, Kathrin, Sass, Christian, Schiefer, Johannes, Schlangen, Christiane, Werner, Cornelius J., Beuth, Markus, Gelderblom, Harald, Priller, Josef, Prüß, Harald, Spruth, Eike, Thiel, Silvia, Andrich, Jürgen, Ellrichmann, Gisa, Herrmann, Lennard, Hoffmann, Rainer, Kaminski, Barbara, Kraus, Peter, Stamm, Christiane, Ganos, Christos, Stubbe, Lars, Tadic, Vera, Tübing, Jennifer, Lange, Herwig, Bosredon, Cecile, Hunger, Ulrike, Löhle, Matthias, Maass, Antonia, Ossig, Christiana, Schmidt, Simone, Storch, Alexander, Wolz, Annett, Wolz, Martin, Kohl, Zacharias, Kozay, Christina, Winkler, Jürgen, Bergmann, Ulrike, Böringer, Regina, Capetian, Philipp, Kammel, Gerit, Lambeck, Johann, Mächtel, Miriam, Meier, Simone, Rijntjes, Michel, Zucker, Birgit, Boelmans, Kai, Goerendt, Ines, Heinicke, Walburgis, Hidding, Ute, Lewerenz, Jan, Münchau, Alexander, Orth, Michael, Schmalfeld, Jenny, Zittel, Simone, Diercks, Gabriele, Dressler, Dirk, Francis, Flverly, Gayde-Stephan, Sabine, Gorzolla, Heike, Kramer, Bianca, Minschke, Rebecca, Schrader, Christoph, Tacik, Pawel, Ribbat+, Michael, Longinus, Bernhard, Möller, Carsten, Bürk, Katrin, Lüsebrink, Antje, Mühlau, Mark, Peinemann, Alexander, Städtler, Michael, Weindl, Adolf, Winkelmann, Juliane, Ziegler, Cornelia, Bechtel, Natalie, Beckmann, Heike, Bohlen, Stefan, Göpfert, Nicole, Hölzner, Eva, Reilmann, Ralf, Rohm, Stefanie, Rumpf, Silke, Schepers, Sigrun, Weber, Nathalia, Bachmeier, Michael, Dose, Matthias, Hofstetter, Nina, Marquard, Ralf, Mühlbäck, Alzbeta, Buck, Andrea, Connemann, Julia, Geitner, Carolin, Kesse, Andrea, Landwehrmeyer, Bernhard, Lezius, Franziska, Nepper, Solveig, Niess, Anke, Schneider, Ariane, Schwenk, Daniela, Süssmuth, Sigurd, Trautmann, Sonja, Vogel, Melanie, Weydt, Patrick, Musacchio, Thomas, Leypold, Christine, Nöth, Kerstin, Cormio, Claudia, Difruscolo, Olimpia, Franco, Giovanni, Nuzzi, Angela, Sciruicchio, Vittorio, Serpino, Claudia, de Tommaso, Marina, Calandra-Buonaura, Giovanna, Capellari, Sabina, Cortelli, Pietro, Gallassi, Roberto, Poda, Roberto, Scaglione, Cesa, Agosti, Chiara, Barlati, Sergio, Compostella, Silvia, Marchina, Eleonora, Padovani, Alessando, Figorilli, Michela, Marrosu, Francesco, Muroni, Antonella, Piras, Valeria, Vacca, Melisa, Bertini, Elisabetta, Bartoli, Caterina, Fortunato, Fernanda, Ghelli, Elena, Ginestroni, Andrea, Mechi, Claudia, Paganini, Marco, Piacentini, Silvia, Pradella, Silvia, Romoli, Anna Maria, Sorbi, Sandro, Abbruzzese, Giovanni, Bandettini di Poggio, Monica, Ferrandes, Giovanna, Mandich, Paola, Marchese, Roberta, Di Maria, Emilio, Tamburini, Tiziano, Albanese, Alberto, Castagliuolo, Simona, Castaldo, Anna, Di Donato, Stefano, Di Bella, Daniela, Gellera, Cinzia, Genitrini, Silvia, Mariotti, Caterina, Nanetti, Lorenzo, Panzeri, Marta, Paridi, Dominga, Soliveri, Paola, Spagnolo, Francesca, Taroni, Franco, Tomasello, Chiara, De Michele, Giuseppe, Di Maio, Luigi, Rinaldi, Carlo, Massarelli, Marco, Peluso, Silvio, Roca, Alessandro, Russo, Cinzia Valeria, Salvatore, Elena, Sorrentino, Pierpaolo, Tucci, Tecla, Cannella, Milena, Codella, Valentina, De Gregorio, Francesca, De Nicola, Annunziata, Elifani, Francesca, Esposito, Chiara, Martino, Tiziana, Mazzante, Irene, Petrollini, Martina, Simonelli, Maria, Vezza, Maurizio, Squitieri, Ferdinando, D'Alessio, Barbara, Lovo, Francesca, Bentivoglio, Anna Rita, Bove, Francesco, Catalli, Claudio, Di Giacopo, Raffaella, Fasano, Alfonso, Frontali, Marina, Guidubaldi, Arianna, Ialongo, Tamara, Jacopini, Gioia, Loria, Giovanna, Modoni, Anna, Petracca, Martina, Piano, Carla, Chiara, Piccininni, Quaranta, Davide, Romano, Silvia, Soleti, Francesco, Solito, Marcella, Spadaro, Maria, Torlizzi, Flavia, Coarelli, Giulia, Ferraldeschi, Michela, Ristori, Giovanni, van Hout, Monique S. E., van Vugt, Jeroen P. P., Marit de Weert, A., Verhoeven, Marloes, Dekker, Meike, Klooster, Jesper, Leenders, Nico, van Oostrom, Joost, Kremer, Berry, Baake, Verena, van den Bogaard, Simon J. A., Dumas, Eve M., t Hart, Ellen P., Hogenboom, Marye, Jacobs, Milou, Jurgens, Caroline, Kampstra, Anne, Schoonderbeek, Anne, Witjes-Ané, Marie-Noëlle, Duits, Annelien, Waber, Mirella, Verstappen, Carla, Blinkenberg, Ellen Økland, Hauge, Erik, Tyvoll, Hilde, Aaserud, Olaf, Aanonsen, Nils Olaf, Bjørgo, Kathrine, Borgerød, Nancy, Dramstad, Elisabeth, Fannemel, Madeleine, Frich, Jan C., Gørvell, Per F., Haggag, Kathrine, Johannessen, Cecilie Haggag, Retterstøl, Lars, Røsby, Oddveig, Rummel, Jutta, Sikiric, Alma, Stokke, Bodil, van Walsem, Marleen, Wehus, Ragnhild, Arntsen, Vibeke, Bjørnevoll, Inga, Sando, Sigrid Botne, Haug, Marte Gjøl, Størseth, Hanna Haugan, Østern, Rune, Paulsen, Julie, Dziadkiewicz, Artur, Konkel, Agnieszka, Narożańska, Ewa, Nowak, Malgorzata, Robowski, Piotr, Sitek, Emilia, Slawek, Jaroslaw, Soltan, Witold, Szinwelski, Michal, Arkuszewski, Michał, Błaszczyk, Magdalena, Boczarska-Jedynak, Magdalena, Ciach-Wysocka, Ewelina, Gorzkowska, Agnieszka, Jasińska-Myga, Barbara, Kaczmarczyk, Aleksandra, Kłodowska – Duda, Gabriela, Opala, Grzegorz, Rudzińska, Monika, Stompel, Daniel, Banaszkiewicz, Krzysztof, Boćwińska, Dorota, Bojakowska-Jaremek, Kamila, Dec, Małgorzata, Grabska, Natalia, Krawczyk, Malgorzata, Kubowicz, Ewelina, Malec-Litwinowicz, Michalina, Stenwak, Agata, Szczudlik, Andrzej, Szczygieł, Elżbieta, Wójcik, Magdalena, Wasielewska, Anna, Anna Bryl, Jacek Anioła, Ciesielska, Anna, Klimberg, Aneta, Marcinkowski, Jerzy, Samara, Husam, Sempołowicz, Justyna, Wiśniewski, Bartłomiej, Gogol (formerly Kalbarczyk), Anna, Janik, Piotr, Jamrozik, Zygmunt, Kaminska, Anna, Kwiecinski+, Hubert, Antczak, Jakub, Jachinska, Katarzyna, Krysa, Wioletta, Rakowicz, Maryla, Rola, Rafal, Ryglewicz, Danuta, Sienkiewicz-Jarosz, Halina, Stępniak, Iwona, Sułek, Anna, Zaremba, Jacek, Zdzienicka, Elzbieta, Ziora-Jakutowicz, Karolina, Januário, Cristina, Júlio, Filipa, Almeida, Manuel, Calado, Ana, Dias, Margarida, Morgado, Joana, Semedo, Cristina, Coelho, Miguel, Magalhães, Andreia, Mendes, Tiago, Neutel, Dulce, Rodrigues, Filipe, Valadas, Anabela, Costa, Cristina, Cardoso, Helena, Santos, Mariana, Cação, Gonçalo, Cavaco, Sara, Damásio, Joana, Fernandes, Joana, Gonçalves, Alexandra, Loureiro, Rui, Moreira, Inês, Magalhães, Marina, Salgado, Paula, Andrade, Carlos, Costa, Andreia, Garrett, Carolina, Gago, Miguel, Guimarães, Joana, Massano, João, Meireles, Joana, Monteiro, Ana, Khasanova, Diana, Zalyalova, Zuleykha, Klyushnikov, Sergey, Sidorova, Olga, Smirnov, Oleg, Antonova, Victoria, Kopishinskaya, Svetlana, Korotysh, Maria, Magzhanov, Rim, Saifullina, Elena, Kurbatov, Sergey, Solis, Pilar, Herrera, Carmen Durán, Moreno, Patrocinio Garcia, Bas, Jordi, Busquets, Núria, Calopa, Matilde, Classen, Serge Jaumà, Dedichá, Nadia Rodríguez, Buongiorno, María Teresa, María, Andrés de la Cerda Santa, Muñoz, Esteban, Santacruz, Pilar, Barbera, Miquel Aguilar, Pardo, Sonia Arribas, Guia, Dolors Badenes, Calzado, Noemi, Hernanz, Laura Casas, Tartari Díaz-Zorita, Juan Pablo, Catena, Judit López, Ferrer, Pilar Quiléz, Carruesco, Gemma Tome, Robert, Misericordia Floriach, Viladrich, Cèlia Mareca, Roca, Elvira, Ruiz Idiago, Jesús Miguel, Riballo, Antonio Villa, Campolongo, Antonia, Fernandez de Bobadilla, Ramon, Bojarsky, Jaime Kulisevsky, Pagonabarraga, Javier, Perez, Jesus Perez, Ribosa, Roser, Villa, Carolina, Acera Gil, Maria Angeles, Corrales, Koldo Berganzo, Gomez Esteban, Juan Carlos, González, Amaia, Merino, Beatriz Tijero, Cubo, Esther, Polo, Cecilia Gil, Mariscal, Natividad, Sánchez, Jesús, Romero, Sandra Gutierrez, Arbelo, José Matías, Malo de Molina, Rocío, Martín, Idaira, Periañez, Juan Manuel, Udaeta, Beatriz, Alonso-Frech, Fernando, Loarte, María del Valle, Barrero, Francisco, Morales, Blas, Frades, Belén, Villanueva, Marina Ávila, Zea Sevilla, Maria Ascension, Fenollar, María del Mar, García-Ramos García, Rocío, Villanueva, Clara, Bascuñana, Mónica, Ventura, Marta Fatás, Caldentey, Juan García, Ribas, Guillermo García, García de Yébenes, Justo, López-Sendón Moreno, José Luis, Barral, Verónica Mañanes, Feliz, Cici, García Ruíz, Pedro José, García, Ana, López, Rosa Guerrero, Bárcenas, Antonio Herranz, Martínez-Descals, Asunción, Pueyo, Angel Martínez, Martin, Veronica Puertas, Martínez, Noelia Rodríguez, Montojo, Teresa, Sainz Artiga, María José, Sánchez, Vicenta, Alarcón, María Dolores, Almagro, Carmen Antúnez, Diéguez, Esther, Fortuna, Lorenza, Legaz, Agustina, Manzanares, Salvadora, Muñoz, Juan Marín, Antequera Torres, María Martirio, Perea, Fuensanta Noguera, Vivancos, Laura, González, Sonia, Guisasola, Luis Menéndez, Prieto, Marta Para, Ribacoba, René, Salvador, Carlos, Lozano, Pablo Sánchez, Ramirez, Inés Legarda, Benito, Dolors Moragues, Arques, Penelope Navas, Lopera, Monica Rodriguez, Pastor, Barbara Vives, Gaston, Itziar, Garcia-Amigot, Fermin, Martinez-Jaurrieta, Maria Dolores, Ramos-Arroyo, Maria Antonia, Adarmes, Astrid, Bernal-Escudero, Maravilla, Carrillo, Fátima, Jesús, Silvia, Mir, Pablo, Vargas-González, Laura, Hermoso, Fátima Damas, García Moreno, José Manuel, Jaramillo, Javier Abril, Lucena, Carolina Mendez, Pacheco Cortegana, Eva María, Peña, José Chacón, Redondo, Luis, Sánchez, Violeta Sánchez, Fernandez, Cristina Melgar, Romero Lemos, María Dolores, Mata, Maite Paredes, Casado, Rocío Villagrán, Bosca, Maria, Burguera, Juan Andres, Brugada, Francisco Castera, Millán Salvador, Jose Maria, Vilaplana, Carmen Peiró, Solís, Pilar, Figuerola, Begoña Jeweinat, Palanca, Paloma Millan, Diago, Elena Bellosta, López del Val, Javier, Martinez, Laura Martinez, López, Elena, Høsterey-Ugander, Ulrika, Fredlund, Gunnel, Constantinescu, Radu, Lewin, Kajsa, Neleborn-Lingefjärd, Liselotte, Berglund, Maria, Berglund, Peter, Linnsand, Petra, Petersén, Åsa, Reimer, Jan, Widner, Håkan, Esmaeilzadeh, Mouna, Tedroff, Joakim, Winnberg, Elisabeth, Benaminov, Stanislav, Björnsson, Elisabeth, Merrick, Daniel, Paucar, Martin, Svenningsson, Per, Wallden, Tina, Berglund, Måns, Loutfi, Ghada, Olofsson, Carina, Stattin, Eva-Lena, Westman, Laila, Wikström, Birgitta, Ekwall, Camilla, Göller, Marie-Lousie, Johansson, Anders, Niemelä, Valter, Nyholm, Dag, Wiklund, Leif, Koehli, Jessica, Stebler, Yanik, Kaelin, Alain, Romero, Irene, Schüpbach, Michael, Zaugg, Sabine Weber, Esposito, Federica, Good, Jean-Marc, Paus, Karin, Vingerhoets, Francois, Wider+, Christian, Jung, Hans H., Petersen, Jens A., Ligon-Auer, Maria, Mihaylova, Violeta, Downie, Lorna, Jack, Roisin, Matheson, Kirsty, Miedzybrodzka, Zosia, Rae, Daniela, Simpson, Sheila A., Summers, Fiona, Ure, Alexandra, Vaughan, Vivien, Harrower, Timothy, Vernon, Nathan, Akhtar, Shahbana, Crooks, Jenny, Curtis, Adrienne, de Souza (Keylock), Jenny, Piedad, John, Rickards, Hugh, Wright, Jan, Haig-Brown, Diane, Craven, Janet, Pallett, Andrew, Simpson, Steve, Weekes, Rebecca, Coulthard, Elizabeth, Gethin, Louise, Hayward, Beverley, Sieradzan, Kasia, Barker, Roger A., O'Keefe, Deidre, Gerrtiz (nee Di Pietro), Anna, Fisher, Kate, Goodman, Anna, Hill, Susan, Mason, Sarah, Swain, Rachel, Guzman, Natalie Valle, Busse, Monica, Butcher, Cynthia, Dunnett, Stephen, Clenaghan, Catherine, Hunt, Sarah, Jones, Lesley, Jones, Una, Khalil, Hanan, Owen, Michael, Price, Kathleen, Rosser, Anne, Goudie, David, Buchanan, Lindsay, Mcfadyen, Paula, Tonner, Alison, Taylor, Anne-Marie, Edwards, Maureen, Carrie, Ho, Mcgill, Marie, Porteous, Mary, Pearson, Pauline, Irvine, Sarah, Brockie, Peter, Foster, Jillian, Johns, Nicola, Mckenzie, Sue, Rothery, Jean, Thomas, Gareth, Yates, Shona, Neumann, Christian, Patterson, Kirsten, Thomson, David, Deith, Catherine, Ireland, Jane, Ritchie, Stuart, Brown, Pauline, Burrows, Liz, Fletcher, Amy, Harding, Alison, Harrison, Kaye, Laver, Fiona, Silva, Mark, Thomson, Aileen, Chu, Carol, Evans, Carole, Gallentree, Deena, Hamer, Stephanie, Kraus, Alison, Markova, Ivana, Raman, Ashok, Rowett, Liz, Andrew, Alyson, Frost, Julie, Noad, Rupert, Cosgrove, Jeremy, Gallantree, Deena, Hobson, Emma, Jamieson, Stuart, Longthorpe, Mandy, Musgrave, Hannah, Peacy, Caroline, Toscano, Jean, Wild, Sue, Yardumian, Pam, Clayton, Carole, Dipple, Heather, Freire-Patino, Dawn, Hallam, Caroline, Middleton, Julia, Alusi, Sundus, Davies, Rhys, Foy, Kevin, Gerrans, Emily, Pate, Louise, Anjum, Uruj, Coebergh, Jan, Eddy, Charlotte, Lahiri, Nayana, Mcentagart, Meriel, Patton, Michael, Peterson, Maria, Rose, Sarah, Andrews, Thomasin, Dougherty, Andrew, Golding, Charlotte, Kavalier, Fred, Laing, Hana, Lashwood, Alison, Robertson, Dene, Ruddy, Deborah, Santhouse, Alastair, Whaite, Anna, Gosling (nee Brown), Stefanie, Bruno, Stefania, Chu, Elvina, Doherty, Karen, Haider, Salman, Hensman, Davina, Lewis, Monica, Novak, Marianne, Patel, Aakta, Robertson, Nicola, Rosser, Elisabeth, Tabrizi, Sarah, Taylor, Rachel, Warner, Thomas, Wild, Edward, Ackermann, Oda, Duport, Sophie, Scott, Adrienne, Stoy, Nicholas, Vaughn, Jenny, Arran, Natalie, Bek, Judith, Craufurd, David, Hare, Marianne, Howard, Liz, Huson, Susan, Johnson, Liz, Jones, Mary, Krishnamoorthy, Ashok, Murphy, Helen, Oughton, Emma, Partington-Jones, Lucy, Sollom, Andrea, Snowden, Julie, Stopford, Cheryl, Thompson, Jennifer, Trender-Gerhard, Iris, Verstraelen (formerly Ritchie), Nichola, Westmoreland, Leann, Cass, Ginette, Davidson, Lynn, Davison, Jill, Fullerton, Neil, Holmes, Katrina, Komati, Suresh, Mcdonnell, Sharon, Mohammed, Zeid, Morgan, Karen, Savage, Lois, Singh, Baldev, Wood, Josh, Knight, Caroline, O'Neill, Mari, Purkayastha, Debasish Das, Nemeth, Andrea H., Siuda, Gill, Valentine, Ruth, Dixon, Kathryn, Armstrong, Richard, Harrison, David, Hughes, Max, Large, Sandra, Donovan, John O., Palmer, Amy, Parkinson, Andrew, Soltysiak, Beverley, Timings, Leanne, Williams, Josh, Burn, John, Bailey, Wendy, Coleman, Caroline, Majeed, Tahir, Verstraelen (Ritchie), Nicola, Barrett, Wendy, Aileen, Ho, Bandmann, Oliver, Bradbury, Alyson, Fairtlough, Helen, Fillingham, Kay, Foustanos, Isabella, Gill, Paul, Kazoka, Mbombe, O'Donovan, Kirsty, Nevitt, Louise, Taylor, Cat, Tidswell, Katherine, Kipps, Christopher, Mackinnon, Lesley, Agarwal, Veena, Hayward, Elaine, Gunner, Kerry, Harris, Kayla, Anderson, Mary, Heywood, Melanie, Keys, Liane, Smalley, Sarah, El-Nimr, George, Duffell, Allison, Wood, Sue, Kennedy (nee Smith), Karen, Gowers, Lesley, Powell, Kingsley, Bethwaite, Pamela, Edwards, Rachel, Fuller, Kathleen, Phillips, Michelle, Tan, Louis, Lau, Puay Ngoh, Pica, Emmanuel, Roos, Raymund AC., Klinische Neurowetenschappen, MUMC+: MA Med Staf Spec Neurologie (9), MUMC+: KIO Kemta (9), Epidemiologie, RS: CAPHRI - R2 - Creating Value-Based Health Care, Klinische Genetica, MUMC+: DA KG Polikliniek (9), and RS: GROW - R4 - Reproductive and Perinatal Medicine
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Male ,HD ,0301 basic medicine ,Pediatrics ,Neurology ,Huntingtin Protein/genetics ,FEATURES ,Disease ,Neuropsychological Tests ,0302 clinical medicine ,Cognitive Dysfunction/psychology ,Medicine ,Family history ,Postural Balance ,Huntington Disease/genetics ,Huntingtin Protein ,education.field_of_study ,Chorea/physiopathology ,Huntington's disease ,Sensation Disorders/physiopathology ,Middle Aged ,Dystonia ,Settore MED/26 - NEUROLOGIA ,Huntington Disease ,neurodegenerative disorders ,Sensation Disorders ,Disease Progression ,Female ,medicine.symptom ,Adult ,medicine.medical_specialty ,Population ,Age of onset ,Late-onset Huntington's disease ,Geriatrics and Gerontology ,Neurology (clinical) ,03 medical and health sciences ,AGE ,Chorea ,Humans ,Cognitive Dysfunction ,education ,Dystonia/physiopathology ,Gait Disorders, Neurologic/physiopathology ,Gait Disorders, Neurologic ,business.industry ,medicine.disease ,Gait ,030104 developmental biology ,Trinucleotide Repeat Expansion ,business ,030217 neurology & neurosurgery ,Balance problems - Abstract
Background: The frequency of late-onset Huntington's disease (>59 years) is assumed to be low and the clinical course milder. However, previous literature on late-onset disease is scarce and inconclusive. Objective: Our aim is to study clinical characteristics of late-onset compared to common-onset HD patients in a large cohort of HD patients from the Registry database. Methods: Participants with late- and common-onset (30–50 years)were compared for first clinical symptoms, disease progression, CAG repeat size and family history. Participants with a missing CAG repeat size, a repeat size of ≤35 or a UHDRS motor score of ≤5 were excluded. Results: Of 6007 eligible participants, 687 had late-onset (11.4%) and 3216 (53.5%) common-onset HD. Late-onset (n = 577) had significantly more gait and balance problems as first symptom compared to common-onset (n = 2408) (P
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- 2019
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23. Energy and angular dependence of the personal dosemeter in use at ITN-DPRSN
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Alves, Joao G., Calado, Ana M., Cardoso, Joao V., and Santos, Luis M.
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- 2008
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24. Bayesian Linear Regression Modelling for Sperm Quality Parameters Using Age, Body Weight, Testicular Morphometry, and Combined Biometric Indices in Donkeys
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Martins-Bessa, Ana, primary, Quaresma, Miguel, additional, Leiva, Belén, additional, Calado, Ana, additional, and Navas González, Francisco Javier, additional
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- 2021
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25. Linear and non-linear regression model fitting of testicular three-dimensional growth in Miranda donkeys
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Martins-Bessa, Ana, primary, Quaresma, Miguel, additional, Leiva, Belén, additional, Calado, Ana, additional, Arando, Ander, additional, Marín, Carmen, additional, and Navas, Francisco Javier, additional
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- 2021
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26. Age-related linear and nonlinear modelling of semen quality parameters in Miranda donkeys
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Martins-Bessa, Ana, primary, Quaresma, Miguel, additional, Leiva, Belén, additional, Calado, Ana, additional, Arando, Ander, additional, Marín, Carmen, additional, and Navas, Francisco Javier, additional
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- 2021
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27. IMPACTO DA FISIOTERAPIA NA CAPACIDADE FUNCIONAL E QUALIDADE DE VIDA DE INDIVÍDUOS COM A SÍNDROME PÓS-POLIOMIELITE
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Calado, Ana Carolina de Lima, primary, Pontes Júnior, Francisco Assis Coutinho, additional, De Freitas Moreira, Karen Lúcia, additional, Lins da Costa, Stênio Melo, additional, Camilo Damião, Maria Eduarda, additional, and Torquato, Isolda Maria Barros, additional
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- 2020
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28. Spoligtyping e polimorfismo do gene pncA: Um cenário em duas etapas para o diagnóstico de Mycobacterium bovis em Portugal
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David, Suzana, Portugal, Clara, Antunes, Abílio, Calado, Ana, Cardoso, Ângela, Barros, Vanessa, Sancho, Luísa, and de Sousa, José Germano
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- 2005
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29. Novos dados sobre os Spoligotypes de estirpes do complexo Mycobacterium tuberculosis isoladas no Hospital Fernando Fonseca (Amadora-Sintra, Portugal)
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David, Suzana, Barros, Vanessa, Portugal, Clara, Antunes, Abílio, Cardoso, Ângela, Calado, Ana, Sancho, Luísa, and de Sousa, José Germano
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- 2005
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30. Identificação molecular pelo método de Spoligotyping de estirpes do complexo Mycobacterium tuberculosis isoladas no Hospital Fernando Fonseca
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David, Suzana, Portugal, Clara, Antunes, Abílio, Cardoso, Ângela, Calado, Ana, Vanessa, Barros, and Sancho, Luísa
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- 2004
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31. Reduced Cancer Incidence in Huntington's Disease: Analysis in the Registry Study
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Mcnulty, Paul, Pilcher, Richard, Ramesh, Raviram, Necuiniate, Renata, Hughes, Alis, Farewell, Daniel, Holmans, Peter, Jones, Lesley, Bonelli, Raphael M., Hecht, Karen, Herranhof, Brigitte, Holl, Anna, Kapfhammer, Hans-Peter, Koppitz, Michael, Lilek, Sabine, Magnet, Markus, Müller, Nicole, Otti, Daniela, Painold, Annamaria, Reisinger, Karin, Scheibl, Monika, Schöggl, Helmut, Ullah, Jasmin, Braunwarth, Eva-Maria, Brugger, Florian, Buratti, Lisa, Hametner, Eva-Maria, Hepperger, Caroline, Holas, Christiane, Hotter, Anna, Hussl, Anna, Larcher, Barbara, Mahlknecht, Philipp, Müller, Christoph, Pinter, Bernadette, Poewe, Werner, Reiter, Eva-Magdalena, Seppi, Klaus, Sprenger, Fabienne, Wenning, Gregor, Ladurner, Gunther, Lilek, Stefan, Sinadinosa, Daniela, Staffen, Wolfgang, Walleczek, Anna Maria, Constant, Eric, Gillardin, Anne-Françoise, Léonard, Marie-Claude, Verellen-Dumoulin, Christine, Van De Wyngaerde, Françoise, Dupuis, Michel, Minet, Cécile, Ribaï, Pascale, Van Paemel, Dominique, Boogaerts, Andrea, Vandenberghe, Wim, Van Reijen, Dimphna, Kaiserova, Michaela, Šenkárová, Zuzana, Klempíř, Jiří, Majerová, Veronika, Roth, Jan, Madsen, Louise Hasselstrøm, Møller, Anette Torvin, Hjermind, Lena, Jacobsen, Oda, Lindquist, Suzanne, Nielsen, Jørgen, Regeur, Lisbeth, Stockholm, Jette, Larsen, Ida Unmack, Vangsted-Hansen, Christina, Vinther-Jensen, Tua, Lolk, Annette, Lundsgaard, Marianne, Wermuth, Lene, Andersson, Christian, Nyberg, Clara, Sundblom, Jimmy, Peippo, Maarit, Sipponen, Marjett, Hartikainen, Paivi, Ollokainen, Mari, Åman, Jaana, Ignatius, Jaakko, Kärppä, Mikko, Mustonen, Aki, Kajula, Outi, Jääskalainen, Outi, Moilanen, Jukka, Santala, Maire, Eklund, Pia, Hiivola, Heli, Hyppönen, Hannele, Martikainen, Kirsti, Tuuha, Katri, Allain, Philippe, Bonneau, Dominique, Bost, Marie, Gohier, Bénédicte, Guérid, Marie-Anne, Olivier, Audrey, Prouzet, Julie, Prundean, Adriana, Scherer-Gagou, Clarisse, Verny, Christophe, Babiloni, Blandine, Debruxelles, Sabrina, Duché, Charlotte, Goizet, Cyril, Jameau, Laetitia, Lafoucrière, Danielle, Spampinato, Umberto, Couttier, Julien, Debilly, Bérengère, Delaigue, Christine, Durif, Franck, Legendre, Perrine, Loiseau, Sylvie, Ulla, Miguel, Vidal, Tiphaine, Bachoud-Lévi, Anne-Catherine, Badei, Farideh, Boissé, Marie-Françoise, Boudali, Lotfi, De Langavant, Laurent Cleret, Lemoine, Laurie, Morgado, Graca, Youssov, Katia, Annic, Agnès, Barthélémy, Recka, De Bruycker, Christelle, Cabaret, Maryline, Carette, Anne-Sophie, Carrière, Nicolas, Decorte, Eric, Defebvre, Luc, Delliaux, Marie, Delval, Arnaud, Depelchin, Alizé, Destee, Alain, Dewulf-Pasz, Nelly, Dondaine, Thibaut, Dugauquier, Florence, Dujardin, Kathy, Hopes, Lucie, Krystkowiak, Pierre, Lemaire, Marie-Hélène, Manouvrier, Sylvie, Mutez, Eugénie, Peter, Mireille, Plomhause, Lucie, Sablonnière, Bernard, Simonin, Clémence, Tard, Céline, Thibault-Tanchou, Stéphanie, Vuillaume, Isabelle, Bellonet, Marcellin, Benoit, Alexandra, Berrisoul, Hassan, Blin, Stéphanie, Courtin, Françoise, Duru, Cécile, Fasquel, Véronique, Flament, Mélanie, Godefroy, Olivier, Mantaux, Béatrice, Playe, Alicia, Roussel, Martine, Tir, Mélissa, Schüler, Béatrice, Wannepain, Sandrine, Azulay, Jean-Philippe, Chabot, Christelle, Delfini, Marie, Eusebio, Alexandre, Fluchere, Frédérique, Grosjean, Hélène, Mundler, Laura, Nowak, Marielle, Raseta, Rolland, Benaich, Sandra, Brice, Alexis, Charles, Perrine, Durr, Alexandra, Ewenczyk, Claire, Francisque, Hélène, Jauffret, Céline, Justo, Damian, Kassar, Abdulrahman, Klebe, Stephan, Lesne, Fabien, Milani, Paolo, Monin, Marie-Lorraine, Roze, Emmanuel, Tataru, Alina, Tchikviladzé, Maya, Bioux, Sandrine, Bliaux, Evangeline, Girard, Carole, Guyant-Maréchal, Lucie, Hannequin, Didier, Hannier, Véronique, Jourdain, Séverine, Maltête, David, Pouliquen, Dorothée, Lagha-Boukbiza, Ouhaid, Longato, Nadine, Marcel, Christophe, Phillipps, Clélie, Rudolf, Gabrielle, Steinmetz, Giséle, Tranchant, Christine, Wagner, Caroline, Zimmermann, Marie-Agathe, Blondeau, Leily, Calvas, Fabienne, Cheriet, Samia, Delabaere, Helène, Demonet, Jean-François, Pariente, Jérémie, Pierre, Michèle, Rolland, Sandrine, Kosinski, Christoph Michael, Milkereit, Eva, Probst, Daniela, Reetz, Kathrin, Sass, Christian, Schiefer, Johannes, Schlangen, Christiane, Werner, Cornelius J., Beuth, Markus, Gelderblom, Harald, Priller, Josef, Prüß, Harald, Spruth, Eike, Thiel, Silvia, Andrich, Jürgen, Ellrichmann, Gisa, Herrmann, Lennard, Hoffmann, Rainer, Kaminski, Barbara, Kraus, Peter, Saft, Carsten, Stamm, Christiane, Lange, Herwig, Maiwald, Robert, Bosredon, Cecile, Hunger, Ulrike, Löhle, Matthias, Maass, Antonia, Ossig, Christiana, Schmidt, Simone, Storch, Alexander, Wolz, Annett, Wolz, Martin, Kohl, Zacharias, Kozay, Christina, Winkler, Jürgen, Bergmann, Ulrike, Böringer, Regina, Capetian, Philipp, Kammel, Gerit, Lambeck, Johann, Mächtel, Miriam, Meier, Simone, Rijntjes, Michel, Zucker, Birgit, Boelmans, Kai, Ganos, Christos, Goerendt, Ines, Heinicke, Walburgis, Hidding, Ute, Lewerenz, Jan, Münchau, Alexander, Orth, Michael, Schmalfeld, Jenny, Stubbe, Lars, Zittel, Simone, Diercks, Gabriele, Dressler, Dirk, Francis, Flverly, Gayde-Stephan, Sabine, Gorzolla, Heike, Kramer, Bianca, Minschke, Rebecca, Schrader, Christoph, Tacik, Pawel, Ribbat, Michael, Longinus, Bernhard, Lüsebrink, Antje, Mühlau, Mark, Peinemann, Alexander, Städtler, Michael, Weindl, Adolf, Winkelmann, Juliane, Ziegler, Cornelia, Bechtel, Natalie, Beckmann, Heike, Bohlen, Stefan, Göpfert, Nicole, Hölzner, Eva, Reilmann, Ralf, Rohm, Stefanie, Rumpf, Silke, Schepers, Sigrun, Weber, Nathalia, Bachmeier, Michael, Dose, Matthias, Hofstetter, Nina, Marquard, Ralf, Mühlbäck, Alzbeta, Barth, Katrin, Buck, Andrea, Connemann, Julia, Ecker, Daniel, Geitner, Carolin, Held, Christine, Kesse, Andrea, Landwehrmeyer, Bernhard, Lezius, Franziska, Nepper, Solveig, Niess, Anke, Schneider, Ariane, Schwenk, Daniela, Süssmuth, Sigurd, Trautmann, Sonja, Vogel, Melanie, Weydt, 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Jenny, Stubbe, Lar, Zittel, Simone, DIercks, Gabriele, Dressler, DIrk, Francis, Flverly, Gayde-Stephan, Sabine, Gorzolla, Heike, Kramer, Bianca, Minschke, Rebecca, Schrader, Christoph, Tacik, Pawel, Ribbat, Michael, Longinus, Bernhard, Lüsebrink, Antje, Mühlau, Mark, Peinemann, Alexander, Städtler, Michael, Weindl, Adolf, Winkelmann, Juliane, Ziegler, Cornelia, Bechtel, Natalie, Beckmann, Heike, Bohlen, Stefan, Göpfert, Nicole, Hölzner, Eva, Reilmann, Ralf, Rohm, Stefanie, Rumpf, Silke, Schepers, Sigrun, Weber, Nathalia, Bachmeier, Michael, Dose, Matthia, Hofstetter, Nina, Marquard, Ralf, Mühlbäck, Alzbeta, Barth, Katrin, Buck, Andrea, Connemann, Julia, Ecker, Daniel, Geitner, Carolin, Held, Christine, Kesse, Andrea, Landwehrmeyer, Bernhard, Lezius, Franziska, Nepper, Solveig, Niess, Anke, Schneider, Ariane, Schwenk, Daniela, Süssmuth, Sigurd, Trautmann, Sonja, Vogel, Melanie, Weydt, Patrick, Musacchio, Thoma, Leypold, Christine, Nöth, Kerstin, Cormio, Claudia, DIfruscolo, Olimpia, Franco, Giovanni, Sciruicchio, Vittorio, Serpino, Claudia, De Tommaso, Marina, Calandra-Buonaura, Giovanna, Capellari, Sabina, Cortelli, Pietro, Gallassi, Roberto, Poda, Roberto, Scaglione, Cesa, Bertini, Elisabetta, Ghelli, Elena, Ginestroni, Andrea, Mechi, Claudia, Paganini, Marco, Piacentini, Silvia, Pradella, Silvia, Romoli, Anna Maria, Sorbi, Sandro, Abbruzzese, Giovanni, DI Poggio, Monica Bandettini, Ferrandes, Giovanna, Mandich, Paola, Marchese, Roberta, DI Maria, Emilio, Albanese, Alberto, Castagliuolo, Simona, Castaldo, Anna, DI Donato, Stefano, DI Bella, Daniela, Gellera, Cinzia, Genitrini, Silvia, Mariotti, Caterina, Monza, Daniela, Nanetti, Lorenzo, Panzeri, Marta, Paridi, Dominga, Soliveri, Paola, Spagnolo, Francesca, Taroni, Franco, Tomasello, Chiara, De Michele, Giuseppe, DI Maio, Luigi, Rinaldi, Carlo, Massarelli, Marco, Peluso, Silvio, Roca, Alessandro, Russo, Cinzia Valeria, Salvatore, Elena, Sorrentino, Pierpaolo, Tucci, Tecla, Cannella, Milena, Codella, Valentina, De Gregorio, Francesca, De Nicola, Annunziata, Elifani, Francesca, Martino, Tiziana, Mazzante, Irene, Petrollini, Martina, Simonelli, Maria, Vezza, Maurizio, Squitieri, Ferdinando, Lovo, Francesca, Bentivoglio, Anna Rita, Bove, Francesco, Catalli, Claudio, DI Giacopo, Raffaella, Fasano, Alfonso, Frontali, Marina, Guidubaldi, Arianna, Ialongo, Tamara, Jacopini, Gioia, Loria, Giovanna, Modoni, Anna, Petracca, Martina, Piano, Carla, Piccininni, Chiara, Quaranta, Davide, Romano, Silvia, Soleti, Francesco, Solito, Marcella, Spadaro, Maria, Torlizzi, Flavia, Zinzi, Paola, Coarelli, Giulia, Ferraldeschi, Michela, Ristori, Giovanni, Van Hout, Monique S.E., Van Vugt, Jeroen P.P., De Weert, A. Marit, Verhoeven, Marloe, Dekker, Meike, Leenders, Nico, Van Oostrom, Joost, Klooster, Jesper, Kremer, Berry, Baake, Verena, Van Den Bogaard, Simon J.A., Bos, Reineke, Dumas, Eve M., Hart't, Ellen P., Kampstra, Anne, Roos, Raymund A.C., Schoonderbeek, Anne, Duits, Annelien, Oosterloo, Mayke, Waber, Mirella, Verstappen, Carla, Blinkenberg, Ellen Økland, Hauge, Erik, Tyvoll, Hilde, Aaserud, Olaf, Bjørgo, Kathrine, Borgeød, Nancy, Dramstad, Elisabeth, Fannemel, Madeleine, Frich, Jan C., Gørvell, Per F., Heiberg, Arvid, Retterstøl, Lar, Røsby, Oddveig, Sikiric, Alma, Stokke, Bodil, Van Walsem, Marleen, Wehus, Ragnhild, Bjørnevoll, Inga, Sando, Sigrid Botne, Haug, Marte Gjøl, Størseth, Hanna Haugan, Arntsen, Vibeke, Dziadkiewicz, Artur, Nowak, Malgorzata, Robowski, Piotr, Sitek, Emilia, Slawek, Jaroslaw, Soltan, Witold, Szinwelski, Michal, Arkuszewski, Michal, Blaszczyk, Magdalena, Boczarska-Jedynak, Magdalena, Ciach-Wysocka, Ewelina, Gorzkowska, Agnieszka, Jasińska-Myga, Barbara, Kaczmarczyk, Aleksandra, Klodowska-Duda, Gabriela, Opala, Grzegorz, Stompel, Daniel, Banaszkiewicz, Krzysztof, Boćwińska, Dorota, Bojakowska-Jaremek, Kamila, Dec, Malgorzata, Grabska, Natalia, Krawczyk, Malgorzata, Kubowicz, Ewelina, Malec-Litwinowicz, Michalina, Rudzińska, Monika, Stenwak, Agata, Szczudlik, Andrzej, Szczygiel, Elzbieta, Wójcik, Magdalena, Wasielewska, Anna, Aniola, Jacek, Bryl, Anna, Ciesielska, Anna, Klimberg, Aneta, Marcinkowski, Jerzy, Samara, Husam, Sempolowicz, Justyna, Wiśniewski, Bartlomiej, Zielonka, Daniel, Gogol, Anna, Janik, Piotr, Jamrozik, Zygmunt, Kaminska, Anna, Kwiecinski, Hubert, Antczak, Jakub, Jachinska, Katarzyna, Krysa, Wioletta, Rakowicz, Maryla, Richter, Przemyslaw, Rola, Rafal, Ryglewicz, Danuta, Sienkiewicz-Jarosz, Halina, Stȩpniak, Iwona, Sulek, Anna, Witkowski, Grzegorz, Zaremba, Jacek, Zdzienicka, Elzbieta, Ziora-Jakutowicz, Karolina, Januário, Cristina, Júlio, Filipa, Almeida, Manuel, Calado, Ana, DIas, Margarida, Morgado, Joana, Semedo, Cristina, Guedes, Leonor Correia, Coelho, Miguel, Ferreira, Joaquim J, Mestre, Tiago, Mendes, Tiago, Valadas, Anabela, Costa, Cristina, Cardoso, Helena, Andrade, Carlo, Costa, Andreia, Garrett, Carolina, Gago, Miguel, Guimarães, Joana, Massano, João, Meireles, Joana, Monteiro, Ana, Herrera, Carmen Durán, Moreno, Patrocinio Garcia, Bas, Jordi, Busquets, Núria, Calopa, Matilde, Classen, Serge Jaumá, Dedichá, Nadia Rodríguez, Buongiorno, María Teresa, De La Cerda Santa María, André, Muñoz, Esteban, Santacruz, Pilar, Barbera, Miquel Aguilar, Sebastián, Ana Rojo, Pardo, Sonia Arriba, Guia, Dolors Badene, Calzado, Noemi, Hernanz, Laura Casa, DÍaz-Zorita, Juan Pablo Tartari, Catena, Judit López, Ferrer, Pilar Quiléz, Carruesco, Gemma Tome, Robert, Misericordia Floriach, Viladrich, Cèlia Mareca, Roca, Elvira, Idiago, Jesús Miguel Ruiz, Villa Riballo, Antonio, Campolongo, Antonia, De Bobadilla, Ramon Fernandez, Bojarsky, Jaime Kulisevsky, Martinez-Horta, Saul, Pagonabarraga, Javier, Perez, Jesus Perez, Ribosa, Roser, Villa, Carolina, Angeles, Maria, Gil, Acera, Corrales, Koldo Berganzo, Esteban, Juan Carlos Gomez, González, Amaia, Merino, Beatriz Tijero, Cubo, Esther, Polo, Cecilia Gil, Mariscal, Natividad, Romero, Sandra Gutierrez, Arbelo, José Matía, De Molina, Rocío Malo, Martín, Idaira, Periañez, Juan Manuel, Udaeta, Beatriz, Alonso-Frech, Fernando, Del Valle Loarte, María, Barrero, Francisco, Morales, Bla, Frades, Belén, Villanueva, Marina Ávila, Sevilla, Maria Ascension Zea, Frech, Fernando Alonso, Del Mar Fenollar, María, García, Rocío García-Ramo, Villanueva, Clara, Garde, Mónica Bascuñana, Ventura, Marta Fatá, Caldentey, Juan García, Ribas, Guillermo García, De Yébenes, Justo García, Moreno, José Luis López-Sendón, Barral, Verónica Mañane, Cubillo, Patricia Trigo, Ruíz, Pedro José García, García, Ana, López, Rosa Guerrero, Bárcenas, Antonio Herranz, Martínez-Descals, Asunción, Martin, Veronica Puerta, Martínez, Noelia Rodríguez, Artiga, María José Sainz, Sánchez, Vicenta, Pueyo, Angel Martínez, Alarcón, Moreau María Dolore, Almagro, Carmen Antúnez, DIéguez, Esther, Fortuna, Lorenza, Manzanares, Salvadora, Muñoz, Juan Marín, Torres, María Martirio Antequera, Perea, Fuensanta Noguera, Vivancos, Laura, González, Sonia, Guisasola, Luis Menéndez, Prieto, Marta Para, Ribacoba, René, Salvador, Carlo, Lozano, Pablo Sánchez, Ramirez, Inés Legarda, Arques, Penelope Nava, Lopera, Monica Rodriguez, Pastor, Barbara Vive, Gaston, Itziar, Garcia-Amigot, Fermin, Martinez-Jaurrieta, Maria Dolore, Ramos-Arroyo, Maria Antonia, Carrillo, Fátima, Redondo, María Teresa Cácere, Mir, Pablo, González, Laura Varga, Hermoso, Fátima Dama, Moreno, Jose Manuel García, Lucena, Carolina Mendez, Cortegana, Eva María Pacheco, Peña, José Chacón, Redondo, Lui, Sánchez, Violeta Sánchez, Fernandez, Cristina Melgar, Lemos, María Dolores Romero, Mata, Maite Parede, Casado, Rocío Villagrán, Bosca, Maria, Burguera, Juan Andre, Brugada, Francisco Castera, Vilaplana, Carmen Peiró, Solís, Pilar, Figuerola, Begoña Jeweinat, Palanca, Paloma Millan, Wahlström, Jan, Høsterey-Ugander, Ulrika, Fredlund, Gunnel, Constantinescu, Radu, Neleborn-Lingefjärd, Liselotte, Berglund, Maria, Berglund, Peter, Linnsand, Petra, Björnsson, Elisabeth, Paucar, Martin, Pålhagen, Sven, Svenningsson, Per, Wallden, Tina, Loutfi, Ghada, Olofsson, Carina, Stattin, Eva-Lena, Westman, Laila, Wikström, Birgitta, Ekwall, Camilla, Göller, Marie-Lousie, Burgunder, Jean-Marc, Stebler, Yanik, Kaelin, Alain, Romero, Irene, Schüpbach, Michael, Zaugg, Sabine Weber, Esposito, Federica, Good, Jean-Marc, Paus, Karin, Vingerhoets, Francoi, Wider, Christian, Jung, Hans H., Petersen, Jens A., Ligon-Auer, Maria, Mihaylova, Violeta, Downie, Lorna, Jack, Roisin, Matheson, Kirsty, Miedzybrodzka, Zosia, Rae, Daniela, Simpson, Sheila A, Summers, Fiona, Ure, Alexandra, Vaughan, Vivien, Harrower, Timothy, Vernon, Nathan, Akhtar, Shahbana, Crooks, Jenny, Curtis, Adrienne, De Souza Keylock, Jenny, Rickards, Hugh, Wright, Jan, Coulthard, Elizabeth, Hayward, Beverley, Sieradzan, Kasia, Wright, Abigail, Barker, Roger A., O'Keefe, Deidre, DI Pietro, Anna Gerrtiz, Fisher, Kate, Goodman, Anna, Hill, Susan, Mason, Sarah, Swain, Rachel, Guzman, Natalie Valle, Busse, Monica, Butcher, Cynthia, Dunnett, Stephen, Clenaghan, Catherine, Fullam, Ruth, Hunt, Sarah, Jones, Una, Khalil, Hanan, Minster, Sara, Owen, Michael, Price, Kathleen, Townhill, Jenny, Rosser, Anne, Goudie, David, Buchanan, Lindsay, McFadyen, Paula, Tonner, Alison, Taylor, Anne-Marie, Edwards, Maureen, Ho, Carrie, McGill, Marie, Porteous, Mary, Pearson, Pauline, Irvine, Sarah, Brockie, Peter, Foster, Jillian, Johns, Nicola, McKenzie, Sue, Rothery, Jean, Thomas, Gareth, Yates, Shona, Deith, Catherine, Ireland, Jane, Ritchie, Stuart, Burrows, Liz, Fletcher, Amy, Harding, Alison, Laver, Fiona, Silva, Mark, Thomson, Aileen, Chu, Carol, Evans, Carole, Gallentree, Deena, Hamer, Stephanie, Kraus, Alison, Markova, Ivana, Raman, Ashok, Andrew, Alyson, Frost, Julie, Noad, Rupert, Hobson, Emma, Jamieson, Stuart, Longthorpe, Mandy, Musgrave, Hannah, Peacy, Caroline, Rowett, Liz, Toscano, Jean, Wild, Sue, Yardumian, Pam, Clayton, Carole, DIpple, Heather, Freire-Patino, Dawn, Hallam, Caroline, Middleton, Julia, Alusi, Sundu, Davies, Rhy, Foy, Kevin, Gerrans, Emily, Pate, Louise, Anjum, Uruj, Coebergh, Jan, Eddy, Charlotte, Lahiri, Nayana, McEntagart, Meriel, Patton, Michael, Peterson, Maria, Rose, Sarah, Andrews, Thomasin, Dougherty, Andrew, Golding, Charlotte, Kavalier, Fred, Laing, Hana, Lashwood, Alison, Robertson, Dene, Ruddy, Deborah, Santhouse, Alastair, Whaite, Anna, Bruno, Stefania, Chu, Elvina, Doherty, Karen, Haider, Salman, Hensman, Davina, Lewis, Monica, Novak, Marianne, Patel, Aakta, Robertson, Nicola, Rosser, Elisabeth, Tabrizi, Sarah, Taylor, Rachel, Warner, Thoma, Wild, Edward, Arran, Natalie, Bek, Judith, Callaghan, Jenny, Craufurd, David, Hare, Marianne, Howard, Liz, Huson, Susan, Johnson, Liz, Jones, Mary, Krishnamoorthy, Ashok, Murphy, Helen, Oughton, Emma, Partington-Jones, Lucy, Rogers, Dawn, Sollom, Andrea, Snowden, Julie, Stopford, Cheryl, Thompson, Jennifer, Trender-Gerhard, Iri, Verstraelen, Nicola, Westmoreland, Leann, Cass, Ginette, Davidson, Lynn, Davison, Jill, Komati, Suresh, McDonnell, Sharon, Mohammed, Zeid, Morgan, Karen, Savage, Loi, Singh, Baldev, Wood, Josh, Knight, Caroline, O'Neill, Mari, Das Purkayastha, Debasish, Nemeth, Andrea H, Siuda, Gill, Valentine, Ruth, Armstrong, Richard, Harrison, David, Hughes, Max, Large, Sandra, Donovan, John O, Palmer, Amy, Parkinson, Andrew, Soltysiak, Beverley, Timings, Leanne, Williams, Josh, Burn, John, Weekes, Rebecca, Craven, Janet, Bailey, Wendy, Coleman, Caroline, Haig-Brown, DIane, Simpson, Steve, Majeed, Tahir, Bandmann, Oliver, Bradbury, Alyson, Fairtlough, Helen, Fillingham, Kay, Foustanos, Isabella, Gill, Paul, Kazoka, Mbombe, O'Donovan, Kirsty, Nevitt, Louise, Peppa, Nadia, Quarrell, Oliver, Taylor, Cat, Tidswell, Katherine, Agarwal, Veena, Anderson, Mary, Gunner, Kerry, Harris, Kayla, Hayward, Elaine, Heywood, Melanie, Keys, Liane, MacKinnon, Lesley, Kipps, Christopher, Smalley, Sarah, Bethwaite, Pamela, Edwards, Rachel, Fuller, Kathleen, Gowers, Lesley, Phillips, Michelle, Powell, Kingsley, Biunno, Ida, Bronzova, Juliana, Giuliano, Joe, Handley, Olivia J., Illarioshkin, Sergey, Illmann, Torsten, Levey, Jamie, McLean, Tim, Koivisto, Susana Pro, Päivärinta, Markku, Uhrova, Tereza, Betz, Sabrina, Come, Adrien, Capodarca, Selene, Charpentier, Sébastien, Da Silva, Wildson Vieira, DI Renzo, Martina, Finisterra, Ana Maria, Genoves, Camille, Gilling, Mette, Hvalstedt, Carina, Koppers, Kerstin, Lamanna, Claudia, Laurá, Matilde, Münkel, Kristina, Mütze, Lisanne, Oehmen, Martin, Padieu, Helene, Paterski, Laurent, Rindal, Beate, Røren, Niini, Šašinková, Pavla, Seliverstov, Yury, Timewell, Erika, Witjes-Ané, Marie-Noelle, Yudina, Elizaveta, Zielonka, Eugeniusz, Mcnulty, Paul, Hannequin, Didier, Diercks, Gabriele, Dressler, Dirk, Difruscolo, Olimpia, Van Hout, Monique S. E., Van Vugt, Jeroen P. P., Van Den Bogaard, Simon J. A., Hart'T, Ellen P., Roos, Raymund A. C., Dias, Margarida, Diéguez, Esther, Mcfadyen, Paula, Mcgill, Marie, Mckenzie, Sue, Dipple, Heather, Mcentagart, Meriel, Mcdonnell, Sharon, Haig-Brown, Diane, Mackinnon, Lesley, and Mclean, Tim
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Adult ,Male ,Adolescent ,Huntington's disease ,cancer ,neurodegeneration ,trinucleotide repeat ,Cellular and Molecular Neuroscience ,Young Adult ,Neoplasms ,Trinucleotide repeat ,Humans ,Genetic Predisposition to Disease ,Prospective Studies ,Registries ,Age of Onset ,Neurodegeneration ,Child ,Aged ,Cancer ,Aged, 80 and over ,Huntingtin Protein ,Incidence ,Infant, Newborn ,Infant ,Middle Aged ,Europe ,Settore MED/26 - NEUROLOGIA ,Huntington Disease ,Huntington’s disease ,Child, Preschool ,Female ,Neurology (clinical) ,Trinucleotide Repeat Expansion - Abstract
Background: People with Huntington's disease (HD) have been observed to have lower rates of cancers. Objective: To investigate the relationship between age of onset of HD, CAG repeat length, and cancer diagnosis. Methods: Data were obtained from the European Huntington's disease network REGISTRY study for 6540 subjects. Population cancer incidence was ascertained from the GLOBOCAN database to obtain standardised incidence ratios of cancers in the REGISTRY subjects. Results: 173/6528 HD REGISTRY subjects had had a cancer diagnosis. The age-standardised incidence rate of all cancers in the REGISTRY HD population was 0.26 (CI 0.22-0.30). Individual cancers showed a lower age-standardised incidence rate compared with the control population with prostate and colorectal cancers showing the lowest rates. There was no effect of CAG length on the likelihood of cancer, but a cancer diagnosis within the last year was associated with a greatly increased rate of HD onset (Hazard Ratio 18.94, p < 0.001). Conclusions: Cancer is less common than expected in the HD population, confirming previous reports. However, this does not appear to be related to CAG length in HTT. A recent diagnosis of cancer increases the risk of HD onset at any age, likely due to increased investigation following a cancer diagnosis.
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- 2018
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32. UTILIZAÇÃO DE SIG APLICADA AOS ESTUDOS DE SOLOS EXPANSIVOS E COLAPSÍVEIS DO ESTADO DO CEARÁ
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Tavares, Camila de Melo, primary, Oliveira, Antônio Italcy de, additional, Calado, Ana Cláudia Almeida, additional, and FERREIRA, SILVIO ROMERO DE MELO, additional
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- 2020
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33. ANÁLISE PEDOLÓGICA E GEOTÉCNICA NA AVALIAÇÃO DA SUSCETIBILIDADE À EROSÃO E DISPERSÃO DOS SOLO DO ESTADO DO CEARÁ
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Calado, Ana Cláudia Almeida, primary, Oliveira, Antônio Italcy de, additional, Tavares, Camila de Melo, additional, and FERREIRA, SILVIO ROMERO DE MELO, additional
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- 2020
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34. Morfologia de Vertissolos da ilha de Fernando de Noronha, Pernambuco, Brasil
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GUEDES, FLÁVIO LEÔNCIO, primary, Tavares, Camila de Melo, additional, Calado, Ana Cláudia Almeida, additional, Aragão, Wilson Ramos, additional, and Santos, José Ivan dos, additional
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- 2020
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35. História do Ensino de Histologia
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Calado, Ana Margarida, primary
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- 2019
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36. Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2
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Calado Ana, Dias Margarida, Januario Cristina, Morgadinho Ana, Ribeiro Maria, Guerreiro Rita, Bras Jose, Semedo Cristina, Oliveira Catarina, Hardy John, and Singleton Andrew
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Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract Background Mutations in the genes PRKN and LRRK2 are the most frequent known genetic lesions among Parkinson's disease patients. We have previously reported that in the Portuguese population the LRRK2 c.6055G > A; p.G2019S mutation has one of the highest frequencies in Europe. Methods Here, we follow up on those results, screening not only LRRK2, but also PRKN, SNCA and PINK1 in a cohort of early-onset and late-onset familial Portuguese Parkinson disease patients. This series comprises 66 patients selected from a consecutive series of 132 patients. This selection was made in order to include only early onset patients (age at onset below 50 years) or late-onset patients with a positive family history (at least one affected relative). All genes were sequenced bi-directionally, and, additionally, SNCA, PRKN and PINK1 were subjected to gene dosage analysis. Results We found mutations both in LRRK2 and PRKN, while the remaining genes yielded no mutations. Seven of the studied patients showed pathogenic mutations, in homozygosity or compound heterozygosity for PRKN, and heterozygosity for LRRK2. Conclusion Mutations are common in Portuguese patients with Parkinson's disease, and these results clearly have implications not only for the genetic diagnosis, but also for the genetic counseling of these patients.
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- 2008
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37. Inspeção e conservação de torres de telecomunicações
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Calado, Ana Patrícia Leite and Machado, Cristina Xavier de Brito
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Torres metálicas ,Corrosion ,Torres de betão armado ,Corrosão ,Inspeção ,Conservação ,Telecommunications ,Steel towers ,Conservation ,InspectionInspection ,Reinforced concrete towers ,Telecomunicações - Abstract
Dissertação de natureza científica para obtenção do grau de mestre em Engenharia Civil na área de especialização de Estruturas Submitted by Sónia Gonçalves (srgoncalves@sa.isel.pt) on 2019-06-25T18:15:25Z No. of bitstreams: 1 Dissertação_1986.pdf: 4411130 bytes, checksum: b0eb44f839cb63452ba5141752c6fc24 (MD5) Made available in DSpace on 2019-06-25T18:15:25Z (GMT). No. of bitstreams: 1 Dissertação_1986.pdf: 4411130 bytes, checksum: b0eb44f839cb63452ba5141752c6fc24 (MD5) Previous issue date: 2017-11-15 N/A
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- 2017
38. Avaliação de um novo processo de produção de Cerveja sem álcool
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Calado, Ana Sofia Pontes, Leitão, Ana, and Vicente, Pedro
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enzima ,Cerveja ,Cerveja sem álcool ,Engenharia e Tecnologia::Outras Engenharias e Tecnologias [Domínio/Área Científica] ,glucose oxidase - Abstract
Numa altura em que os consumidores se encontram cada vez mais atentos ao desenvolvimento de novos produtos, surge a necessidade das empresas inovarem e tentarem ganhar vantagem competitiva em relação aos seus concorrentes de mercado. Desta forma, e, sabendo que a cerveja sem álcool para alguns consumidores, se encontra apenas direcionada para certas ocasiões, como em casos de gravidez, condução, doença, entre outros, e, devido às suas características organoléticas, nomeadamente o seu sabor doce e a mosto, surge a necessidade de encontrar soluções que tornem esta cerveja mais atrativa para os consumidores. Como tal, este trabalho de dissertação, desenvolvido na Sociedade Central de Cervejas e Bebidas, pretendeu avaliar um novo processo de produção de cervejas sem álcool, nomeadamente, recorrendo à adição de uma enzima, glucose oxidase. Esta enzima converte a glucose em ácido glucónico, diminuindo a doçura e aumentando a acidez, o que promove uma melhoria das suas características organoléticas, sem que seja necessário recorrer à adição de ácidos, como é feito atualmente. Assim, foram realizados vários ensaios em laboratório, simulando diversas condições de produção, de forma a avaliar o comportamento desta enzima. Os objetivos propostos para a fase laboratorial seriam, atingir o pH previsto inicialmente de X a uma temperatura de Y ºC e com condições de arejamento normais, ou seja, aquelas que são utilizadas em produção, com uma posterior inativação da enzima por pasteurização. Apesar dos inúmeros constrangimentos encontrados durante a realização dos ensaios, os objetivos propostos inicialmente foram cumpridos. No entanto, a passagem deste novo processo para uma fase industrial, não foi possível, uma vez que as condições de pasteurização utilizadas em produção não são suficientes para uma inativação enzimática.
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- 2017
39. The Effect of Flaxseed in Breast Cancer: A Literature Review
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Calado, Ana, primary, Neves, Pedro Miguel, additional, Santos, Teresa, additional, and Ravasco, Paula, additional
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- 2018
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40. Adenocarcinoma do Cólon e Polimiosite Paraneoplásica: a Importância do Programa de Reabilitação
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Neves, Ana Filipa, Serviço de MFR, Centro Hospitalar Lisboa Central, Lisboa, Portugal, and Calado, Ana
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Colorectal Neoplasms/rehabilitation ,Polymyositis/rehabilitation ,Neoplasias Colorectais/reabilitação ,Polimiosite/reabilitação - Published
- 2016
41. Evaluation of thermo-physical properties and drying kinetics of carrots in a convective hot air drying system
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Guiné, Raquel, Gonçalves, João Carlos, Calado, Ana Rita, and Correia, Paula
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enthalpy ,mass transfer coefficient ,thermal conductivity ,diffusivity ,kinetic model ,heat transfer coefficient - Abstract
This paper presents an experimental study on the evolution of carrot properties along convective drying by hot air at different temperatures (50ºC, 60ºC and 70ºC). The thermo-physical properties calculated were: specific heat, thermal conductivity, diffusivity, enthalpy, heat and mass transfer coefficients. Furthermore, the data of drying kinetics were treated and adjusted according to the three empirical models: Page, Henderson & Pabis and Logarithmic. The sorption isotherms were also determined and fitted using the GAB model. The results showed that, generally, the thermo-physical properties presented a decline during the drying process, and the decrease was faster for the temperature of 70ºC. It was possible to verify that the Page model presented the best prediction ability for the representation of kinetics of the drying process. The GAB model used to fit the sorption isotherms showed a good prediction capacity and, at a given water activity, despite some variations, the amount of water sorbed increased with the decrease of drying temperature.
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- 2016
42. Hipertrofia das raízes nervosas da cauda equina em dois casos de Charcot-Marie-Tooth tipo 1A com agravamento clínico subagudo
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Fernandes, Andreia, Sequeira, João, Melancia, Diana, Veiga, Marcos, Dias, Margarida, Calado, Ana, Henriques, Isabel, and Pedrosa, Rui
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- 2016
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43. Utilização dos glóbulos vermelhos no doente grave : estudo de uma amostra de doentes admitidos no SMI do CHUC
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Calado, Ana Rebeca das Neves and Pimentel, Jorge
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Concentrado de Eritrócitos ,Anemia ,Unidade de Cuidados Intensivos ,Guidelines ,Transfusões de Sangue ,Prática - Abstract
Trabalho de revisão do 6º ano médico com vista à atribuição do grau de mestre (área científica de medicina intensiva) no âmbito do ciclo de estudos de Mestrado Integrado em Medicina Introdução: Transfusões de Concentrado de Eritrócitos são uma prática muito comum nas Unidades de Cuidados Intensivos. Apesar dos benefícios comprovados no tratamento de doentes severamente anémicos, os riscos que comportam não são desprezíveis e a sua disponibilidade é limitada. Embora atualmente se defenda a adoção de uma prática restritiva (Hb
- Published
- 2016
44. O legado de 'Antoninho das Cantigas': semear, contar, partilhar
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Rico, Tânia Morais, Calado, Ana Leonor Regueira, and Câmara Municipal de Elvas
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Tradição Oral ,António Tomás Pires, Contos Populares Portugueses, Tradição Oral ,António Tomás Pires ,Contos Populares Portugueses - Abstract
António Tomás Pires (n. 1850 - m. 1913), elvense, foi um dos mais notáveis etnógrafos portugueses da nossa história. Incansável, durante trinta anos, procedeu à recolha de costumes, tradições, superstições, contos populares, etc., por todo o Alentejo, e principalmente no concelho de Elvas. A sua pesquisa foi publicada em jornais e revistas regionais e nacionais, e deu origem a várias edições monográficas como o “Cancioneiro Popular Político” ou os “Cantos Populares Portugueses”. É este importante legado que no ano letivo de 2015/2016 será trabalhado e divulgado pelo Serviço Educativo da Biblioteca Municipal de Elvas junto à comunidade local e escolar, através de um conjunto coordenado de ações. Este projeto tem por objectivo divulgar e dar a conhecer, este notável elvense e a sua obra, a partilha da tradição oral por ele compilada e formar contadores que a corporizem junto à população local.A realização deste projeto irá alicerçar-se nos seguintes momentos: Enquadramento histórico e percurso do etnógrafo elvense António Tomás Pires no âmbito da recolha efectuada por este da tradição oral; Importância deste Património Imaterial para uma cidade como Elvas, elevada há três anos a Património da Humanidade, tendo em conta que um dos principais vectores que norteia a sua política patrimonial no passado, presente e futuro é a salvaguarda e dinamização do seu Património Cultural.Como dinamizar este legado junto à comunidade local e escolar.O primeiro momento é dedicado a António Tomás Pires, a quem o povo na época chamava o “Antoninho das Cantigas” devido ao incansável esforço e dedicação com que este investigador realizava a sua recolha com “…a paciência beneditina de andar pelos serões, pelas fontes e pelos soalheiros a pedir às raparigas que lhe ditassem trovas de bater às portas das velhas para estas lhe ensinarem contos da carochinha,…” como citava Leite Vasconcelos, numa época em que tais métodos eram encarados com desdém e desconfiança por muitos. Sem dúvida, uma das mais importantes figuras na história da recolha da tradição oral portuguesa, António Tomás Pires, ocupa um lugar entre os grandes vultos que se dedicaram entre 1875 e 1915 a esta inventariação, classificação e compilação dos contos populares portugueses. O segundo momento irá contextualizar a importância deste Património Imaterial no desenvolvimento e crescimento cultural de uma comunidade local e escolar que após a classificação a 30 de Junho de 2012 a Património Mundial, se encontra predisposta e sedenta de aprender e apreender a sua História. O valor da contribuição de António Tomás Pires a quem o precedeu foi reconhecido e deverá ser relembrado no presente junto à comunidade local, e perpetuado pelas gerações vindouras. O terceiro momento visa assinalar os objectivos e a metodologia do projeto com que o Serviço Educativo da Biblioteca Municipal de Elvas irá dinamizar o legado de António Tomás Pires junto à comunidade local e escolar. Este projeto irá arrancar com a abertura do ano lectivo de 2015/2016 e visa divulgar e dar a conhecer, este notável elvense e a sua obra, a partilha da tradição oral por ele compilada e formar contadores que a corporizem junto à população local. Para a sua concretização teremos vários parceiros: a comunidade escolar, as associações culturais locais, a Universidade Sénior, o Projeto Memóriamedia, o Centro de Recursos da Tradição Oral e Património Imaterial do Concelho de Évora, o Museu nacional de Arqueologia, entre outros. Como Mário F. Lages sintetiza em relação à recolha efectuada por António Tomás Pires: “…destes contos. Na sua beleza singela, colocam-nos na escola simbólica do passado, uma escola que necessita de ser redescoberta e frequentada por todos, crianças e adultos…”, e é partindo desta premissa que se pretende desenvolver este projeto. O conto e o contador, o contador e o conto, e o ouvinte, serão aspectos cruciais que serão trabalhados juntamente com a divulgação da obra de António Tomás Pires.Semear, contar, partilhar de modo a materializar a memória de um povo, dar vida à Palavra. Recontar o Conto Tradicional para garantir a sua sobrevivência.
- Published
- 2015
45. Variação da composição nutricional e propriedades de cenouras durante a secagem
- Author
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Calado, Ana Rita Pinto, Guiné, Raquel, Correia, Paula, and Gonçalves, João Carlos
- Subjects
Kinetic ,Valor nutritivo ,Thermo-physical properties ,Propriedade térmica ,Physicochemical properties ,Textura ,Teor em cinza ,Secagem ,Teor em humidade ,Propriedade físico-química ,Teor em hidratos de carbono ,Cinética ,Proteína bruta ,Carrot ,Cenoura ,Cor ,Drying - Abstract
Este trabalho teve como objetivo a determinação das propriedades da cenoura (Daucus carota L.), da variedade Nantes, antes, durante e após a secagem por convecção a três temperaturas diferentes (50, 60 e 70 ºC).De forma a verificar as alterações ao nível de diferentes propriedades, tais como: propriedades químicas (humidade, proteínas, fibras, cinzas, açúcares e 'aw') propriedades físicas (textura, cor, porosidade e densidade) e propriedades termofísicas (calor específico, condutividade térmica, difusividade e entalpia). Dos resultados obtidos foi possível concluir que a temperatura de secagem de 70 º C foi a que mais afetou as propriedades químicas analisadas, tais como a humidade, proteínas e açúcares redutores, onde estes sofreram uma diminuição ao longo das secagens. A 'aw' também apresentou uma diminuição ao longo das secagens, onde apresentou um menor valor na secagem a 70 ºC, tendo passado de 0,97 para 0,69, enquanto as temperaturas de 50 ºC e 60 ºC apresentaram um valor final igual, de 0,74. No que diz respeito às propriedades físicas, verificou-se que em relação à textura registaram-se evoluções semelhantes em termos de dureza, mastigabilidade e gomosidade, na medida em que sofreram uma acentuada diminuição nas primeiras horas de secagem, e a temperatura de 70 ºC foi a que mais afetou estas propriedades. No caso da cor a temperatura de 60 ºC foi a que provocou uma maior diferença de cor, a qual ao longo da secagem esta foi aumentando. A porosidade sofreu um aumento com as secagens devido à diminuição da humidade, no entanto a temperatura de 70 ºC foi a que obteve uma menor porosidade, e as temperaturas de 50 ºC e 60 ºC apresentaram valores de porosidade semelhantes. As propriedades termofísicas registaram uma diminuição ao longo da secagem, onde o calor específico sofreu uma maior diminuição com a temperatura de 70 ºC, passando de 3,90 kJ/kg.K para 1,99 kJ/kg.K. A condutividade térmica também sofreu uma maior diminuição com a temperatura de 70 ºC, diminuindo de 0,5243 W/m.K para 0,2782 W/m.K. A difusividade foi de igual forma afetada pela temperatura de 70 ºC, tendo diminuído de 1,50×10-7 m2/s para 1,06×10-7 m2/s. No caso da entalpia, esta sofreu uma maior diminuição com a temperatura de 50 ºC, passando de 233 J/kg para 96,7 J/kg. As isotérmicas de sorção foram ajustadas ao modelo de GAB, onde se verificou que apesar de algumas oscilações a quantidade de água sorvida a uma determinada aw, aumentou com a diminuição da temperatura.Os dados da cinética de secagem foram tratados e ajustados de acordo com três modelos: Page, Henderson & Pabis e Logarítmico, tendo-se verificado que o modelo de Page foi o que mostrou melhor descrever os processos em estudo, enquanto o pior modelo para descrever a cinética de secagem foi o Logarítmico. ABSTRACT: his study aimed to determine the properties of Nantes carrots (Daucus carota L.), before, during and after the process of drying by convection, at three different temperatures (50, 60 e 70 ºC), in order to verify the variations of the different properties such as chemical properties (moisture, protein, fiber, ash, sugars and aw), physical properties (texture, color, density and porosity) and thermo-physical properties (specific heat, thermal conductivity, diffusivity and enthalpy). From the gathered data it was possible to conclude that the drying temperature of 70 ºC was the one that most affected the chemical properties analyzed, such as moisture, protein and reduced sugars. Over the drying process, the 'aw' showed a decreasing in value, presenting a lower value while drying at 70 ºC, from 0,97 to 0,69, and at the temperatures of 50 ºC and 60 ºC showed a final value of 0,74. Concerning the physical properties, it was found that regarding the texture, similar changes were recorded in terms of hardness, gumminess and chewiness, during the first hours of drying when there was a sharp decrease in these properties, being the temperature of 70 ºC the one that most affected these properties. Regarding the color, the drying temperature of 60 ºC was the one that induced more change in color, increasing throughout de drying process. The porosity increased with the drying due to the decrease in humidity. However the temperature of 70 ºC was the one that showed less porosity, while the temperatures of 50 ºC and 60 ºC presented similar values. The thermo-physical properties experienced a decline during the drying process, where the specific heat has suffered a greater decrease with the temperature of 70 ºC, from 3,90 kJ/kg.K to 1,99 kJ/kg.K. The thermal conductivity also experienced agreater decrease with the temperature of 70 °C, decreasing from 0,5243 W/m.K to 0,2782 W/m.K. The diffusivity wase qually affected by the temperature of 70 ºC, which decreased from 1,50×10-7 m2/s to1,06×10-7 m2/s. In the case of the enthalpy, it showed a greater decrease with the temperature of 50 ºC, going from 233 J/kg to 96,7 J/kg. The sorption isotherms were fitted to the GAB model where it was found that, despite some variations, the amount of water sorbed at a given 'aw' increased with the decrease in temperature. The data of drying kinetics were treated and adjusted according to three models: Page, Henderson & Pabis and logarithmic. It was possible to verify that the Page model was the onet hat best described the process at study, and the worst model to describe the drying kinetics was the logarithmic.
- Published
- 2014
46. O Conceito da Logística Inversa para a Gestão de Resíduos numa U/E/O do Exército Português – O Caso da Academia Militar
- Author
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Calado, Ana
- Subjects
Cadeia de Abastecimento ,Fluxos Físicos Inversos ,Academia Militar ,Logística Inversa ,Gestão de Resíduos - Abstract
O presente Trabalho de Investigação Aplicada encontra-se subordinado ao tema “O Conceito da Logística Inversa para a Gestão de Resíduos numa U/E/O do Exército Português – O Caso da Academia Militar”. Ao longo dos últimos anos o ser humano é responsável por um crescente consumo de recursos naturais não renováveis, que consequentemente provoca o aumento da produção de resíduos, colocando em causa a sustentabilidade das gerações vindouras. Torna-se imperativo a utilização de novas medidas para a minimização da perda de matérias-primas, nomeadamente o aparecimento de fluxos físicos inversos na cadeia de abastecimento. Assim, esta investigação visa aferir a correta aplicabilidade da logística inversa, por forma a alcançar a eficiência na gestão de resíduos numa Unidade/Estabelecimento/Órgão do Exército Português, particularmente na Academia Militar. A metodologia utilizada durante a elaboração do trabalho para a recolha de informação teve por base a pesquisa bibliográfica, a análise documental, as observações diretas e participantes, bem como os inquéritos por entrevista. Os resultados obtidos nesta investigação demonstram que a logística inversa é aplicada com alguns entraves devido a um processo de abate moroso e armazenamento provisório dos resíduos em locais não apropriados durante um período prolongado, correndo o risco de perda de valor. Conclui-se que é necessário tornar o processo de abate mais célere, desenvolver áreas específicas para a triagem e armazenamento dos resíduos na Academia Militar e racionalizar o transporte. Abstract This work lies under the theme “The Concept of Reverse Logistics for Waste Management in a U/E/O - The Case of the Military Academy”. Over the past few years the human being has been responsible for an increasing consumption of non-renewable natural resources, which in turn causes increased production of waste, jeopardizing the sustainability of future generations. It becomes imperative to use new measures to minimize the loss of raw materials, namely the appearance of physical flows in the reverse supply chain. Thus, this research aims to assess the correct applicability of reverse logistics in order to achieve efficiency in waste management within the Unit / Establishment / Organ of the Portuguese Army, particularly at the Military Academy. The methodology used to collect information during this work was based on bibliographic research, document analysis, direct and participants observations, as well as interview surveys. The present results demonstrate that reverse logistics is applied with some obstacles due to a lengthy process of slaughter and storage of waste not suitable for a long period, the risk of loss of value locations. I tis concluded that it is necessary to make the process faster slaughter, develop specific areas for sorting and storage of waste at the Military Academy and streamline transport.
- Published
- 2014
47. Electron Microscopy Findings inN-Methyl-N-Nitrosourea-Induced Mammary Tumors
- Author
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Faustino-Rocha, Ana I., primary, Calado, Ana M., additional, Gama, Adelina, additional, Ferreira, Rita, additional, Ginja, Mário, additional, and Oliveira, Paula A., additional
- Published
- 2016
- Full Text
- View/download PDF
48. Time Evolution of Physicochemical Properties of Carrots During the Drying Process
- Author
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Rita P. Calado, Ana, primary, Carlos Gonçalves, Joao, additional, M. R. Correia, Paula, additional, and P. F. Guiné, Raquel, additional
- Published
- 2016
- Full Text
- View/download PDF
49. O impacto do programa integrado para o autismo (PIPA)
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Lima, Cláudia Bandeira de, Afonso, Catarina, Calado, Ana Catarina, Torgal, Fernanda, Gouveia, Rosa, Nascimento, Catarina, and Repositório da Universidade de Lisboa
- Subjects
Autismo ,Intervenção multidisciplinar ,Programa PIPA - Abstract
A Perturbação do Espectro do Autismo é uma patologia que atinge a maioria das áreas do desenvolvimento normal de uma criança. É uma doença crónica que exige um acompanhamento ao longo da vida. A Academia Americana de Pediatria recomenda que a intervenção seja iniciada o mais precoce possível, multidisciplinar e de carácter intensivo. Neste sentido, o Centro de Desenvolvimento Infantil LógicaMentes criou um Programa Integrado Para o Autismo (PIPA). Trata-se de um Programa de carácter intensivo e multidisciplinar dirigido a crianças e a famílias. Objectivo: Apresentação do Programa PIPA e avaliação do seu impacto na intervenção do Autismo. Metodologia: Terapia intensiva através do Programa PIPA – programa multidisciplinar com a participação de quatro especialidades: Pediatria do Neurodesenvolvimento, Psicologia, Terapia da Fala e Psicomotricidade. O PIPA inclui intervenção directa com a criança, a família e a escola. Apresenta-se uma revisão de 21 casos que frequentaram o Programa PIPA, com resultados estatísticos de dois momentos distintos de avaliação (antes e após intervenção). Resultados: Após sete anos de aplicação, os resultados do Programa PIPA têm sido muito positivos, quer ao nível da promoção das competências pessoais de cada criança, quer ao nível da sua melhor integração familiar, educacional e social. Os resultados revelam uma diferença estatisticamente significativa no perfil cognitivo e linguístico das crianças e uma diminuição da frequência do diagnóstico da perturbação autista. Conclusão: Os resultados realçam a eficácia do Programa PIPA e da terapia de carácter intensivo na intervenção com crianças com autismo e no suporte psicológico às suas famílias. The Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that affects many areas of children’s development. The American Academy of Pediatrics recommends that intervention should start as early as possible and should be multidisciplinary and intensive in nature.The Child Development Clinic LógicaMentes has created the Autism Integrated Program (PIPA) for intervention in ASD - a multidisciplinary and intensive Program for children and their families.Purpose: To evaluate the effect of multidisciplinary intensive therapies in intervention of autism, through the implementation of the Autism Integrated Program (PIPA). Methodology: Intensive therapy with the PIPA Program. This is a multidisciplinary intervention consisting of four specialized areas Neurodevelomental Pediatrics, Psychology, Speech and Language Therapy and Psychomotor Therapy. It includes direct intervention with the child, family and school. We reviewed 21 cases, all diagnosed with ASD (DSM-IV-TR criteria), who participated in the PIPA program. The results were analyzed statistically in two different assessment moments (before and after intervention). Results: After seven years of implementation, the results of PIPA Program have been very positive in the promotion of each child’s personal skills, and in family, educational and social integration. The results show statistically significant changes in linguistic and cognitive profile of these children and a decrease in the diagnosis of autistic disorder. Conclusion: The results highlight the efficacy of PIPA program and its intensive therapy nature in the intervention of autistic children and in the psychological support of their families.
- Published
- 2013
50. Fatores de risco para infeção associada a cateter venoso central:revisão sistemática
- Author
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Raposo, Sílvia Cristina, Cristina Martins, Calado, Ana, Pereira, Filipa, Correia, Teresa I. G., and Martins, Matilde
- Subjects
Fatores de risco ,Infeções relacionadas com cateter ,Cateteres venosos centrais - Abstract
O uso de Cateter Venoso Central é apontado como um importante fator de risco para infeção, aumentando a mortalidade e morbilidade, bem como o período de internamento e os custos associados. Objetivo: Identificar os fatores de risco para a infeção associados à utilização de Cateter Venoso Central em doentes adultos hospitalizados. Foram selecionados 30 artigos através dos descritores, Cateteres Venosos Centrais, Infeções Relacionadas com Cateter e Fatores de Risco por consulta eletrónica nas bases de dados PubMed, Lilacs e Scielo. Foram definidos como critérios de inclusão, estudos publicados entre 2007 e 2013, realizados em adultos hospitalizados com utilização de Cateter Venoso Central, estarem publicados em língua portuguesa e em revistas com indexação ISI. Obteve-se uma total de 8 publicações tendo rejeitado 22 por não cumprirem os critérios de inclusão. Do total dos 8 estudos analisados, 62,5% referiram como fatores de risco para a infecção do Cateter Venoso Central, o local de inserção, tendo sido a veia femoral e a jugular referidas em 37% dos estudos como os locais mais prevalentes. O tempo de permanência do Cateter foi outro dos factores de risco encontrado em 75% dos estudos, sendo que a grande maioria verificou correlação positiva do risco de infeção do Cateter com o número de dias de permanência. O maior número de lúmenes do Cateter foi referido também como fator de risco em 50% dos estudos e em igual proporção a falta de cuidados na manutenção do Cateter, devido a uma má manipulação do mesmo aumentando o risco de infeção. Igualmente a situação clínica do doente constituiu um fator de risco em 50% dos estudos, sendo que a gravidade da história clínica elevou o risco de infeção. O aumento do tempo de internamento foi outro fator de risco referido em 12,5% dos estudos. Tendo em conta o elevado número de fatores de risco associados às infecções do Cateter Venoso Central, torna-se fundamental ter conhecimento dos mesmos com vista à sua redução, pois é necessária a implementação de medidas de controlo de infeção por parte dos profissionais de saúde, quer no momento da sua inserção quer no seu manuseamento de forma a prevenir esta infeção.
- Published
- 2013
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