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1. Application of the Weighted-Incidence Syndromic Combination Antibiogram (WISCA) to guide the empiric antibiotic treatment of febrile neutropenia in oncological paediatric patients: experience from two paediatric hospitals in Northern Italy

Author

Liberati, Cecilia, Donà, Daniele, Maestri, Linda, Petris, Maria Grazia, Barbieri, Elisa, Gallo, Elisa, Gallocchio, Jacopo, Pierobon, Marta, Calore, Elisabetta, Zin, Annachiara, Brigadoi, Giulia, Mariani, Marcello, Mesini, Alessio, Saffioti, Carolina, Ugolotti, Elisabetta, Gregori, Dario, Giaquinto, Carlo, Castagnola, Elio, and Biffi, Alessandra

Published
2024
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2. Letermovir for Cytomegalovirus infection in pediatric patients undergoing allogenic hematopoietic stem cell transplantation: a real-life study by the Infectious Diseases Working Group of Italian Association of Pediatric Hematology-Oncology (AIEOP)

Author

Galaverna, Federica, Baccelli, Francesco, Zama, Daniele, Tridello, Gloria, Masetti, Riccardo, Soncini, Elena, Mura, Rossella, Barzaghi, Federica, Colombini, Antonella, Prunotto, Giulia, D’Amico, Maria Rosaria, Calore, Elisabetta, Biffi, Alessandra, Perruccio, Katia, Gasperini, Pietro, Oltolini, Chiara, Quagliarella, Francesco, Giacomazzi, Alice, Pagliara, Daria, Locatelli, Franco, and Cesaro, Simone

Published
2024
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3. Influence of invasive aspergillosis during acute leukaemia treatment on survival after allogeneic stem cell transplantation: a prospective study of the EBMT Infectious Diseases Working Party

Author

Penack, Olaf, Tridello, Gloria, Salmenniemi, Urpu, Martino, Rodrigo, Khanna, Nina, Perruccio, Katia, Fagioli, Franca, Richert-Przygonska, Monika, Labussière-Wallet, Hélène, Maertens, Johan, Jubert, Charlotte, Aljurf, Mahmoud, Pichler, Herbert, Kriván, Gergely, Kunadt, Desiree, Popova, Marina, Gabriel, Melissa, Calore, Elisabetta, Blau, Igor Wolfgang, Benedetti, Fabio, Itäla-Remes, Maija, de Kort, Elizabeth, Russo, Domenico, Faraci, Maura, Ménard, Anne-Lise, Borne, Peter von dem, Poiré, Xavier, Yesilipek, Akif, Gozdzik, Jolanta, Yeğin, Zeynep Arzu, Yañez, Lucrecia, Facchini, Luca, Van Gorkom, Gwendolyn, Thurner, Lorenz, Kocak, Ulker, Sampol, Antònia, Zuckerman, Tsila, Bierings, Marc, Mielke, Stephan, Ciceri, Fabio, Wendel, Lotus, Knelange, Nina, Mikulska, Malgorzata, Averbuch, Dina, Styczynski, Jan, Camara, Rafael de la, and Cesaro, Simone

Published
2024
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4. Favorable outcome of SARS-CoV-2 infection in pediatric hematology oncology patients during the second and third pandemic waves in Italy: a multicenter analysis from the Infectious Diseases Working Group of the Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP)

Author

Zama, Daniele, Baccelli, Francesco, Colombini, Antonella, Contino, Amalia, Calore, Elisabetta, Petris, Maria Grazia, Meneghello, Linda, Mercolini, Federico, Lo Vecchio, Andrea, Montalto, Shana, Meazza, Cristina, Barone, Angelica, Compagno, Francesca, Muggeo, Paola, Soncini, Elena, Brescia, Letizia, Giraldi, Eugenia, Giurici, Nagua, Mura, Rosa Maria, Cellini, Monica, Perruccio, Katia, Petroni, Valeria, La Spina, Milena, Ziino, Ottavio, Burnelli, Roberta, De Santis, Raffaella, Mascarin, Maurizio, Barretta, Valentina, Tridello, Gloria, and Cesaro, Simone

Published
2022
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5. Listeria monocytogenes Infections in Hematopoietic Cell Transplantation Recipients: Clinical Manifestations and Risk Factors. A Multinational Retrospective Case-Control Study from the Infectious Diseases Working Party of the European Society for Blood and Marrow Transplantation

Author

Averbuch, Dina, Tridello, Gloria, Wendel, Lotus, Itälä-Remes, Maija, Oren, Ilana, Karas, Michal, Blijlevens, Nicole, Beguin, Yves, Broers, Annoek, Calore, Elisabetta, Cattaneo, Chiara, Isaksson, Cecilia, Robin, Christine, Gadisseur, Alain, Maertens, Johan, De Becker, Ann, Lueck, Catherina, Metafuni, Elisabetta, Pichler, Herbert, Popova, Marina, Ram, Ron, Yeshurun, Moshe, Mikulska, Malgorzata, Camara, Rafael de la, and Styczynski, Jan

Published
2024
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6. Phase II Study of Allogeneic Hematopoietic Stem Cell Transplantation for Children with High-Risk Neuroblastoma Using a Reduced-Intensity Conditioning Regimen: Results from the AIEOP Trial

Author

Prete, Arcangelo, Lanino, Edoardo, Saglio, Francesco, Biffi, Alessandra, Calore, Elisabetta, Faraci, Maura, Rondelli, Roberto, Favre, Claudio, Zecca, Marco, Casazza, Gabriella, Porta, Fulvio, Luksch, Roberto, Cesaro, Simone, Rabusin, Marco, Parasole, Rosanna, Mura, Rosa Maria, Lo Nigro, Luca, Leardini, Davide, Pagliara, Daria, Locatelli, Franco, and Fagioli, Franca

Published
2024
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7. Long-Term Complications after Allogeneic Hematopoietic Stem Cell Transplantation with Treosulfan- or Busulfan-Based Conditioning in Pediatric Patients with Acute Leukemia or Myelodysplastic Syndrome: Results of an Associazione Italiana Ematologia Oncologia Pediatrica Retrospective Study

Author

Saglio, Francesco, Pagliara, Daria, Zecca, Marco, Balduzzi, Adriana, Cattoni, Alessandro, Prete, Arcangelo, Tambaro, Francesco Paolo, Faraci, Maura, Calore, Elisabetta, Locatelli, Franco, and Fagioli, Franca

Published
2024
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8. Listeria monocytogenes infections in hematopoietic cell transplant recipients: clinical manifestations and risk factors: A multinational retrospective case control study of the Infectious Diseases Working Party (IDWP) of the European Society for Blood and Marrow Transplantation (EBMT).

Author

Averbuch, Dina, primary, Tridello, Gloria, additional, Wendel, Lotus, additional, Itälä-Remes, Maija, additional, Oren, Ilana, additional, Karas, Michal, additional, Blijlevens, Nicole, additional, Beguin, Yves, additional, Broers, Annoek, additional, Calore, Elisabetta, additional, Cattaneo, Chiara, additional, Isaksson, Cecilia, additional, Robin, Christine, additional, Gadisseur, Alain, additional, Maertens, Johan, additional, De Becker, Ann, additional, Lueck, Catherina, additional, Metafuni, Elisabetta, additional, Pichler, Herbert, additional, Popova, Marina, additional, Ram, Ron, additional, Yeshurun, Moshe, additional, Mikulska, Malgorzata, additional, Camara, Rafael de la, additional, and Styczynski, Jan, additional

Published
2024
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9. Pneumocystis Pneumonia After Allogeneic Hematopoietic Cell Transplantation: A Case-Control Study on Epidemiology and Risk Factors on Behalf of the Infectious Diseases Working Party of the European Society for Blood and Marrow Transplantation

Author

Robin, Christine, Cordonnier, Catherine, Tridello, Gloria, Knelange, Nina, Xhaard, Alienor, Chantepie, Sylvain, Tanguy-Schmidt, Aline, Schouten, Harry C., Yeshurun, Moshe, Rocha, Vanderson, Srour, Micha, Kröger, Nicolaus, Ledoux, Marie-Pierre, Dalgaard, Jakob, Thiebaut, Anne, Giardino, Stefano, Calore, Elisabetta, Zuckerman, Tsila, Groll, Andreas H., Raida, Ludek, Avcin, Simona, Vicent, Marta Gonzalez, Kaare, Ain, Drozd-Sokolowska, Joanna, Turlure, Pascal, Bretagne, Stéphane, Mikulska, Malgorzata, Camara, Rafael de la, Cesaro, Simone, and Styczynski, Jan

Published
2024
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10. Safety and efficacy of brincidofovir for Adenovirus infection in children receiving allogeneic stem cell transplantation: an AIEOP retrospective analyses

Author

Perruccio, Katia, Menconi, Mariacristina, Galaverna, Federica, Pagliara, Daria, Carraro, Francesca, Fagioli, Franca, Calore, Elisabetta, Biffi, Alessandra, Baretta, Valentina, Massei, Maria Speranza, Capolsini, Ilaria, Faraci, Maura, Verna, Marta, Soncini, Elena, Caniglia, Maurizio, Locatelli, Franco, and Cesaro, Simone

Published
2021
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11. A multicentre, multinational, prospective, observational registry study of defibrotide in patients diagnosed with veno-occlusive disease/sinusoidal obstruction syndrome after haematopoietic cell transplantation: an EBMT study

Author

Mohty, Mohamad, Battista, Marta Lisa, Blaise, Didier, Calore, Elisabetta, Cesaro, Simone, Maximova, Natalia, Perruccio, Katia, Renard, Cecile, Wynn, Robert, Zecca, Marco, Labopin, Myriam, Hanvesakul, Raj, Amber, Vian, Ryan, Robert J., Lawson, Sarah, and Ciceri, Fabio

Published
2021
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13. Long-term complications after allogeneic hematopoietic stem cell transplantation for pediatric patients with acute leukemia or myelodysplastic syndrome given either a Treosulfan- or a Busulfan-based conditioning regimen: results of an AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) retrospective study

Author

Saglio, F, Pagliara, D, Zecca, M, Balduzzi, A, Cattoni, A, Prete, A, Tambaro, F, Faraci, M, Calore, E, Locatelli, F, Fagioli, F, Saglio, Francesco, Pagliara, Daria, Zecca, Marco, Balduzzi, Adriana, Cattoni, Alessandro, Prete, Arcangelo, Tambaro, Francesco Paolo, Faraci, Maura, Calore, Elisabetta, Locatelli, Franco, Fagioli, Franca, Saglio, F, Pagliara, D, Zecca, M, Balduzzi, A, Cattoni, A, Prete, A, Tambaro, F, Faraci, M, Calore, E, Locatelli, F, Fagioli, F, Saglio, Francesco, Pagliara, Daria, Zecca, Marco, Balduzzi, Adriana, Cattoni, Alessandro, Prete, Arcangelo, Tambaro, Francesco Paolo, Faraci, Maura, Calore, Elisabetta, Locatelli, Franco, and Fagioli, Franca

Abstract

Patients undergoing hematopoietic stem cell transplantation (HSCT) for hematologic malignancies during childhood have an increased risk of developing long-term sequelae that are in part attributable to the conditioning regimen. The present study aimed to assess the occurrence of long-term toxicities in a population of children who underwent HSCT for hematologic malignancies using either treosulfan or busulfan in the conditioning regimen. The cumulative incidences of growth impairment, altered gonadal function, altered thyroid function, cataracts, secondary malignant neoplasia, and altered pulmonary function were evaluated retrospectively by univariable and multivariable analyses in a population of 521 pediatric patients with acute leukemias or myelodysplastic syndromes treated in 20 Italian transplant centers affiliated with the Associazione Italiana Ematologia ed Oncologia Pediatrica (AIEOP). The median duration of follow-up for the entire study population was 7.1 years (range, 1 to 16 years). Overall, a larger proportion of patients given busulfan developed long-term toxicities compared to patients treated with treosulfan (34% versus 20%; P = .01). In univariable analysis, gonadal toxicity developed in 10% of patients who received treosulfan (95% confidence interval [CI], 3% to 15%), compared with 38% (95% CI, 24% to 39%) of busulfan-treated patients (P = .02), and this finding was confirmed by multivariable analysis (relative risk, .51; 95% CI, .34 to .76; P = .0009). We did not find any statistically significant associations between the occurrence of other long-term toxicities and the use of either busulfan or treosulfan. This study provides evidence that the use of treosulfan is correlated with a reduced incidence of gonadal toxicity in children undergoing HSCT for hematologic malignancies.

Published
2024

15. Intercontinental study on pre-engraftment and post-engraftment Gram-negative rods bacteremia in hematopoietic stem cell transplantation patients: Risk factors and association with mortality

Author

Averbuch, Diana, Tridello, Gloria, Hoek, Jennifer, Mikulska, Malgorzata, Pabst, Thomas, Yaňez San Segundo, Lucrecia, Akan, Hamdi, Özçelik, Tülay, Donnini, Irene, Klyasova, Galina, Botelho de Sousa, Aida, Zuckerman, Tsila, Tecchio, Cristina, de la Camara, Rafael, Aki, Sahika Zeynep, Ljungman, Per, Gülbas, Zafer, Nicolas-Virelizier, Emmanuelle, Calore, Elisabetta, Perruccio, Katia, Ram, Ron, Annaloro, Claudio, Martino, Rodrigo, Avni, Batia, Shaw, Peter J., Jungova, Alexandra, Codeluppi, Katia, O'Brien, Tracey, Waszczuk-Gajda, Anna, Batlle, Montserrat, Pouli, Anastasia, Lueck, Catherina, Gil, Lidia, Iacobelli, Simona, Styczynski, Jan, Engelhard, Dan, and Cesaro, Simone

Published
2020
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16. Occurrence of long-term effects after hematopoietic stem cell transplantation in children affected by acute leukemia receiving either busulfan or total body irradiation: results of an AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) retrospective study

Author

Saglio, Francesco, Zecca, Marco, Pagliara, Daria, Giorgiani, Giovanna, Balduzzi, Adriana, Calore, Elisabetta, Favre, Claudio, Faraci, Maura, Prete, Arcangelo, Tambaro, Francesco Paolo, Quarello, Paola, Locatelli, Franco, and Fagioli, Franca

Published
2020
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17. Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease after Autologous or Allogeneic Hematopoietic Stem Cell Transplantation in Children: a retrospective study of the Italian Hematology-Oncology Association–Hematopoietic Stem Cell Transplantation Group

Author

Faraci, Maura, Bertaina, Alice, Luksch, Roberto, Calore, Elisabetta, Lanino, Edoardo, Saglio, Francesco, Prete, Arcangelo, Menconi, Mariacristina, De Simone, Giusy, Tintori, Veronica, Cesaro, Simone, Santarone, Stella, Orofino, Maria Grazia, Locatelli, Franco, and Zecca, Marco

Published
2019
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18. SARS-CoV-2 Infection in the Pediatric Oncology Population: The Definitive Comprehensive Report of the Infectious Diseases Working Group of AIEOP.

Author

Zama, Daniele, Zanaroli, Andrea, Corbelli, Agnese, Vecchio, Andrea Lo, Bene, Margherita Del, Colombini, Antonella, Compagno, Francesca, Barone, Angelica, Fontanili, Ilaria, D'Amico, Maria Rosaria, Papa, Maria Rosaria, Petris, Maria Grazia, Calore, Elisabetta, Montalto, Shana, Meneghello, Linda, Brescia, Letizia, Mura, Rosamaria, Spina, Milena La, Muggeo, Paola, and Rinieri, Simona

Subjects
PEDIATRIC oncology, COMMUNICABLE diseases, HEMATOPOIETIC stem cell transplantation, REPORTING of diseases, SARS-CoV-2
Abstract

Objective The objective of this study was to assess the clinical impact and outcome of the SARS-CoV-2 infection on children with cancer or those who received a hematopoietic stem cell transplantation. Methods AIEOP (Italian Association of Pediatric Hematology and Oncology) performed a nationwide multicenter observational cohort study, including consecutive patients between April 2020 and November 2022. Results Twenty-five Italian centers participated and 455 patients were enrolled. We reported a significant increasing trend of symptomatic cases over the years, while the number of nonmild infections remained stable. Early infection after oncologic diagnosis (<60 days) and severe neutropenia were identified as independent risk factors for developing moderate, severe, or critical infections. The percentage of patients who were asymptomatic and mildly symptomatic and who stopped chemotherapy reduced over the years of the pandemic. Nine patients died, but no death was attributed to SARS-CoV-2 infection. Conclusions SARS-CoV-2 infection presented a self-limiting benign course in the Italian pediatric oncohematology population during the pandemic, and its main consequence has been the discontinuation of cancer-directed therapies. The rate of patients who were asymptomatic and stopped chemotherapy reduced over the years, suggesting that the continuation of chemotherapy is a feasible option. [ABSTRACT FROM AUTHOR]

Published
2024
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19. The SARS-CoV-2 infection in the pediatric oncology population: the definitive comprehensive report of Infectious Diseases Working Group (IDWG) of AIEOP

Author

Zama, Daniele, primary, Zanaroli, Andrea, additional, Corbelli, Agnese, additional, Lo Vecchio, Andrea, additional, Del Bene, Margherita, additional, Colombini, Antonella, additional, Compagno, Francesca, additional, Barone, Angelica, additional, Fontanili, Ilaria, additional, D’Amico, Maria Rosaria, additional, Papa, Maria Rosaria, additional, Petris, Maria Grazia, additional, Calore, Elisabetta, additional, Montalto, Shana, additional, Meneghello, Linda, additional, Brescia, Letizia, additional, Mura, Rosamaria, additional, La Spina, Milena, additional, Muggeo, Paola, additional, Rinieri, Simona, additional, Meazza, Cristina, additional, Perruccio, Katia, additional, Cellini, Monica, additional, Spadea, Manuela, additional, Mercolini, Federico, additional, Petroni, Valeria, additional, De Santis, Raffaella, additional, Soncini, Elena, additional, Provenzi, Massimo, additional, Giurici, Nagua, additional, Ziino, Ottavio, additional, Tridello, Gloria, additional, and Cesaro, Simone, additional

Published
2023
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20. Pneumocystis pneumonia after allogeneic hematopoietic cell transplantation: A case-control study on epidemiology and risk factors on behalf of the Infectious Diseases Working Party of the European Society for Blood and Marrow Transplantation

Author

Robin, Christine, primary, Cordonnier, Catherine, additional, Tridello, Gloria, additional, Knelange, Nina, additional, Xhaard, Alienor, additional, Chantepie, Sylvain, additional, Tanguy-Schmidt, Aline, additional, Schouten, Harry C, additional, Yesherun, Moshe, additional, Rocha, Vanderson, additional, Srour, Micha, additional, Kröger, Nicolaus, additional, Ledoux, Marie-Pierre, additional, Dalgaard, Jakob, additional, Thiebaut, Anne, additional, Giardino, Stefano, additional, Calore, Elisabetta, additional, Zuckerman, Tsila, additional, Groll, Andreas H, additional, Raida, Ludek, additional, Avcin, Simona, additional, Vicent, Marta Gonzalez, additional, Kaare, Ain, additional, Drozd-Sokolowska, Joanna, additional, Turlure, Pascal, additional, Bretagne, Stéphane, additional, Mikulska, Malgorzata, additional, Camara, Rafael de la, additional, Cesaro, Simone, additional, and Styczynski, Jan, additional

Published
2023
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23. Safety and efficacy of brincidofovir for Adenovirus infection in children receiving allogeneic stem cell transplantation: an AIEOP retrospective analyses

Author

Perruccio, Katia, Menconi, Mariacristina, Galaverna, Federica, Pagliara, Daria, Carraro, Francesca, Fagioli, Franca, Calore, Elisabetta, Biffi, Alessandra, Baretta, Valentina, Massei, Maria Speranza, Capolsini, Ilaria, Faraci, Maura, Verna, Marta, Soncini, Elena, Caniglia, Maurizio, Locatelli, Franco, and Cesaro, Simone

Published
2024
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24. Vaccination practices in pediatric transplantation: A survey among member centers of the European reference network TransplantChild.

Author

Donà, Daniele, Bravo‐Gallego, Luz Yadira, Remacha, Esteban Frauca, Cananzi, Mara, Gastaldi, Andrea, Canizalez, Juan Torres, Stephenne, Xavier, Lacaille, Florence, Lindemans, Caroline, Calore, Elisabetta, Galea, Nathalie, Benetti, Elisa, Nachbaur, Edith, Sandes, Ana Rita, Teixeira, Ana, Ferreira, Sandra, Klaudel‐Dreszler, Maja, Ackermann, Oanez, Boyer, Olivia, and Espinosa, Laura

Subjects
CHICKENPOX, VACCINATION, CHICKENPOX vaccines, VACCINATION coverage, MMR vaccines, HEMATOPOIETIC stem cell transplantation
Abstract

Background: There is considerable variation in vaccination practices between pediatric transplant centers. This study aims to evaluate active immunization attitudes and practices among ERN‐TransplantChild centers and identify potential areas of improvement that could be addressed by shared evidence‐based protocols. Methods: A cross‐sectional questionnaire of attitudes and practices toward immunization of pediatric SOT and HSCT candidates and recipients was sent to a representative member of multidisciplinary teams from 27 European centers belonging to the ERN‐TransplantChild. Results: A total of 28/62 SOT programs and 6/12 HSCT programs across 21 European centers participated. A quarter of centers did not have an on‐site protocol for the immunizations. At the time of transplantation, pediatric candidates were fully immunized (80%–100%) in 57% and 33% of the SOT and HSCT programs. Variations in the time between vaccine administration and admission to the waiting list were reported between the centers, with 2 weeks for inactivated vaccines and variable time (2–4 weeks) for live‐attenuated vaccines (LAVs). Almost all sites recommended immunization in the post‐transplant period, with a time window of 4–8 months for the inactivated vaccines and 16–24 months for MMR and Varicella vaccines. Only five sites administer LAVs after transplantation, with seroconversion evaluated in 80% of cases. Conclusions: The immunization coverage of European pediatric transplant recipients is still inconsistent and far from adequate. This survey is a starting point for developing shared evidence‐based immunization protocols for safe vaccination among pediatric transplant centers and generating new research studies. [ABSTRACT FROM AUTHOR]

Published
2023
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30. ECTHYMA GANGRENOSUM IN CHILDREN WITH CANCER: DIAGNOSIS AT A GLANCE. A retrospective study form the Infection Working Group of Italian Pediatric Hematology Oncology Association.

Author

Muggeo, Paola, primary, Zama, Daniele, additional, Decembrino, Nunzia, additional, Onofrillo, Daniela, additional, Frenos, Stefano, additional, Colombini, Antonella, additional, Perruccio, Katia, additional, Calore, Elisabetta, additional, Giurici, Nagua, additional, Ficara, Monica, additional, Spina, Milena La, additional, Mura, Rosamaria, additional, Santis, Raffaela De, additional, Santoro, Nicola, additional, and Cesaro, Simone, additional

Published
2022
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31. Consensus on COVID-19 Vaccination in Pediatric Oncohematological Patients, on Behalf of Infectious Working Group of Italian Association of Pediatric Hematology Oncology

Author

Cesaro, Simone, primary, Muggeo, Paola, additional, Zama, Daniele, additional, Cellini, Monica, additional, Perruccio, Katia, additional, Colombini, Antonella, additional, Carraro, Francesca, additional, Petris, Maria Grazia, additional, Petroni, Valeria, additional, Mascarin, Maurizio, additional, Baccelli, Francesco, additional, Soncini, Elena, additional, Mura, Rosamaria, additional, La Spina, Milena, additional, Decembrino, Nunzia, additional, Burnelli, Roberta, additional, Frenos, Stefano, additional, Castagnola, Elio, additional, Faraci, Maura, additional, Meazza, Cristina, additional, Barzaghi, Federica, additional, D’Amico, Maria Rosaria, additional, Capasso, Maria, additional, Calore, Elisabetta, additional, Ziino, Ottavio, additional, Barone, Angelica, additional, Compagno, Francesca, additional, Luti, Laura, additional, Galaverna, Federica, additional, De Santis, Raffaella, additional, Brescia, Letizia, additional, Meneghello, Linda, additional, Petrone, Angelamaria, additional, Giurici, Nagua, additional, Onofrillo, Daniela, additional, Schumacher, Fabian, additional, and Mercolini, Federico, additional

Published
2022
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32. Current Practices on Diagnosis, Prevention and Treatment of Post-Transplant Lymphoproliferative Disorder in Pediatric Patients after Solid Organ Transplantation: Results of ERN TransplantChild Healthcare Working Group Survey

Author

Baker, Alastair, primary, Frauca Remacha, Esteban, additional, Torres Canizales, Juan, additional, Bravo-Gallego, Luz Yadira, additional, Fitzpatrick, Emer, additional, Alonso Melgar, Angel, additional, Muñoz Bartolo, Gema, additional, Garcia Guereta, Luis, additional, Ramos Boluda, Esther, additional, Mozo, Yasmina, additional, Broniszczak, Dorota, additional, Jarmużek, Wioletta, additional, Kalicinski, Piotr, additional, Maecker-Kolhoff, Britta, additional, Carlens, Julia, additional, Baumann, Ulrich, additional, Roy, Charlotte, additional, Chardot, Christophe, additional, Benetti, Elisa, additional, Cananzi, Mara, additional, Calore, Elisabetta, additional, Dello Strologo, Luca, additional, Candusso, Manila, additional, Lopes, Maria Francelina, additional, Brito, Manuel João, additional, Gonçalves, Cristina, additional, Do Carmo, Carmen, additional, Stephenne, Xavier, additional, Wennberg, Lars, additional, Stone, Rosário, additional, Rascon, Jelena, additional, Lindemans, Caroline, additional, Turkiewicz, Dominik, additional, Giraldi, Eugenia, additional, Nicastro, Emanuele, additional, D’Antiga, Lorenzo, additional, Ackermann, Oanez, additional, and Jara Vega, Paloma, additional

Published
2021
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33. Current Practices on Diagnosis, Prevention and Treatment of Post-Transplant Lymphoproliferative Disorder in Pediatric Patients after Solid Organ Transplantation: Results of ERN TransplantChild Healthcare Working Group Survey

Author

UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique, Baker, Alastair, Frauca Remacha, Esteban, Torres Canizales, Juan, Bravo-Gallego, Luz Yadira, Fitzpatrick, Emer, Alonso Melgar, Angel, Muñoz Bartolo, Gema, Garcia Guereta, Luis, Ramos Boluda, Esther, Mozo, Yasmina, Broniszczak, Dorota, Jarmużek, Wioletta, Kalicinski, Piotr, Maecker-Kolhoff, Britta, Carlens, Julia, Baumann, Ulrich, Roy, Charlotte, Chardot, Christophe, Benetti, Elisa, Cananzi, Mara, Calore, Elisabetta, Dello Strologo, Luca, Candusso, Manila, Lopes, Maria Francelina, Brito, Manuel João, Gonçalves, Cristina, Do Carmo, Carmen, Stephenne, Xavier, Wennberg, Lars, Stone, Rosário, Rascon, Jelena, Lindemans, Caroline, Turkiewicz, Dominik, Giraldi, Eugenia, Nicastro, Emanuele, D’Antiga, Lorenzo, Ackermann, Oanez, Jara Vega, Paloma, UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique, Baker, Alastair, Frauca Remacha, Esteban, Torres Canizales, Juan, Bravo-Gallego, Luz Yadira, Fitzpatrick, Emer, Alonso Melgar, Angel, Muñoz Bartolo, Gema, Garcia Guereta, Luis, Ramos Boluda, Esther, Mozo, Yasmina, Broniszczak, Dorota, Jarmużek, Wioletta, Kalicinski, Piotr, Maecker-Kolhoff, Britta, Carlens, Julia, Baumann, Ulrich, Roy, Charlotte, Chardot, Christophe, Benetti, Elisa, Cananzi, Mara, Calore, Elisabetta, Dello Strologo, Luca, Candusso, Manila, Lopes, Maria Francelina, Brito, Manuel João, Gonçalves, Cristina, Do Carmo, Carmen, Stephenne, Xavier, Wennberg, Lars, Stone, Rosário, Rascon, Jelena, Lindemans, Caroline, Turkiewicz, Dominik, Giraldi, Eugenia, Nicastro, Emanuele, D’Antiga, Lorenzo, Ackermann, Oanez, and Jara Vega, Paloma

Abstract

Background: Post-transplant lymphoproliferative disease (PTLD) is a significant complication of solid organ transplantation (SOT). However, there is lack of consensus in PTLD management. Our aim was to establish a present benchmark for comparison between international centers and between various organ transplant systems and modalities; (2) Methods: A cross-sectional questionnaire of relevant PTLD practices in pediatric transplantation was sent to multidisciplinary teams from 17 European center members of ERN TransplantChild to evaluate the centers' approach strategies for diagnosis and treatment and how current practices impact a cross-sectional series of PTLD cases; (3) Results: A total of 34 SOT programs from 13 European centers participated. The decision to start preemptive treatment and its guidance was based on both EBV viremia monitoring plus additional laboratory methods and clinical assessment (61%). Among treatment modalities the most common initial practice at diagnosis was to reduce the immunosuppression (61%). A total of 126 PTLD cases were reported during the period 2012-2016. According to their histopathological classification, monomorphic lesions were the most frequent (46%). Graft rejection after PTLD remission was 33%. Of the total cases diagnosed with PTLD, 88% survived; (4) Conclusions: There is still no consensus on prevention and treatment of PTLD, which implies the need to generate evidence. This might successively allow the development of clinical guidelines.

Published
2021

38. A mixed-methods study of the disease experience in hematopoietic stem cell transplantation survivors: the contribution of text analysis

Author

Sinatora, Francesco, primary, Di Florio, Nicoletta, additional, Traverso, Annalisa, additional, Zanato, Silvia, additional, Porreca, Alessio, additional, Tremolada, Marta, additional, Tumino, Manuela, additional, Marzollo, Antonio, additional, Mainardi, Chiara, additional, Gabelli, Maria, additional, Calore, Elisabetta, additional, Pillon, Marta, additional, Cattelan, Chiara, additional, Messina, Chiara, additional, and Basso, Giuseppe, additional

Published
2020
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40. Ecthyma Gangrenosum in Children With Cancer: Diagnosis at a Glance: A Retrospective Study From the Infection Working Group of Italian Pediatric Hematology Oncology Association.

Author

Muggeo, Paola, Zama, Daniele, Decembrino, Nunzia, Onofrillo, Daniela, Frenos, Stefano, Colombini, Antonella, Perruccio, Katia, Calore, Elisabetta, Giurici, Nagua, Ficara, Monica, La Spina, Milena, Mura, Rosamaria, De Santis, Raffaella, Santoro, Nicola, and Cesaro, Simone

Published
2022
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43. Extracorporeal photochemotherapy for paediatric patients with graft-versus-host disease after haematopoietic stem cell transplantation

Author

MESSINA, CHIARA, LOCATELLI, FRANCO, LANINO, EDOARDO, UDERZO, CORNELIO, ZACCHELLO, GRAZIELLA, CESARO, SIMONE, PILLON, MARTA, PEROTTI, CESARE, DEL FANTE, CLAUDIA, FARACI, MAURA, RIVABELLA, LUCIA, CALORE, ELISABETTA, DE STEFANO, PIETRO, ZECCA, MARCO, GIORGIANI, GIOVANNA, BRUGIOLO, ALESSANDRA, BALDUZZI, ADRIANA, DINI, GIORGIO, ZANESCO, LUIGI, and DALLʼAMICO, ROBERTO

Published
2003

45. Central nervous system fungal infections in allogeneic stem cell transplantation. Outcome of 24 recent cases and literature review

Author

Candoni, Anna, primary, Facchin, Gabriele, additional, Busca, Alessandro, additional, Lazzarotto, Davide, additional, Cattaneo, Chiara, additional, Nadali, Gianpaolo, additional, Klimko, Nicholai, additional, Del Principe, Maria Ilaria, additional, Castagnola, Carlo, additional, Verga, Luisa, additional, Zannier, Maria Elena, additional, Calore, Elisabetta, additional, Capelli, Debora, additional, Perruccio, Katia, additional, Melillo, Lorella, additional, Fanin, Renato, additional, and Pagano, Livio, additional

Published
2019
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46. A Multi-Center, Multinational, Prospective Observational Registry Study of Defibrotide in Patients Diagnosed with Severe Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Cell Transplantation (HCT)

Author

Mohty, Mohamad, primary, Battista, Marta Lisa, additional, Blaise, Didier, additional, Calore, Elisabetta, additional, Cesaro, Simone, additional, Gassas, Adam, additional, Maximova, Natalia, additional, Perruccio, Katia, additional, Renard, Cecile, additional, Wynn, Robert, additional, Zecca, Marco, additional, Labopin, Myriam, additional, Hanvesakul, Raj, additional, Ryan, Robert J., additional, Ciceri, Fabio, additional, and Lawson, Sarah, additional

Published
2019
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47. Results of Unrelated Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease in Europe on Behalf of Paediatric Diseases (PDWP) and Inborn Errors Working Parties (IEWP) of the EBMT

Author

Gluckman, Eliane, primary, de la Fuente, Josu, additional, Cappelli, Barbara, additional, Scigliuolo, Graziana M., additional, Volt, Fernanda, additional, Tozatto-Maio, Karina, additional, Rocha, Vanderson, additional, Mina, Tommaso, additional, O'Boyle, Farah, additional, Smiers, Frans, additional, Bettoni Da Cunha-Riehm, Claudia, additional, Calore, Elisabetta, additional, Bonanomi, Sonia, additional, Graphakos, Stelios, additional, Paisiou, Anna, additional, Albert, Michael H., additional, Ruggeri, Annalisa, additional, Zecca, Marco, additional, Lankester, Arjan C., additional, and Corbacioglu, Selim, additional

Published
2019
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48. Pediatric transplantation in Europe during the COVID‐19 pandemic: Early impact on activity and healthcare.

Author

Doná, Daniele, Torres Canizales, Juan, Benetti, Elisa, Cananzi, Mara, De Corti, Federica, Calore, Elisabetta, Hierro, Loreto, Ramos Boluda, Esther, Melgosa Hijosa, Marta, Garcia Guereta, Luis, Pérez Martínez, Antonio, Barrios, Maribel, Costa Reis, Patricia, Teixeira, Ana, Lopes, Maria Francelina, Kaliciński, Piotr, Branchereau, Sophie, Boyer, Olivia, Debray, Dominque, and Sciveres, Marco

Subjects
COVID-19 pandemic, HEMATOPOIETIC stem cell transplantation, CHILD patients, COVID-19, TRANSPLANTATION of organs, tissues, etc.
Abstract

The current pandemic SARS‐CoV‐2 has required an unusual allocation of resources that can negatively impact chronically ill patients and high‐complexity procedures. Across the European Reference Network on Pediatric Transplantation (ERN TransplantChild), we conducted a survey to investigate the impact of the COVID‐19 outbreak on pediatric transplant activity and healthcare practices in both solid organ transplantation (SOT) and hematopoietic stem cell transplantation (HSCT). The replies of 30 professionals from 18 centers in Europe were collected. Twelve of 18 centers (67%) showed a reduction in their usual transplant activity. Additionally, outpatient visits have been modified and restricted to selected ones, and the use of telemedicine tools has increased. Additionally, a total of 14 COVID‐19 pediatric transplanted patients were identified at the time of the survey, including eight transplant recipients and six candidates for transplantation. Only two moderate‐severe cases were reported, both in HSCT setting. These survey results demonstrate the limitations in healthcare resources for pediatric transplantation patients during early stages of this pandemic. COVID‐19 disease is a major worldwide challenge for the field of pediatric transplantation, where there will be a need for systematic data collection, encouraging regular discussions to address the long‐term consequences for pediatric transplantation candidates, recipients, and their families. [ABSTRACT FROM AUTHOR]

Published
2020
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49. Alternative Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease in Europe

Author

Cappelli, Barbara, primary, Scigliuolo, Graziana Maria, additional, Volt, Fernanda, additional, Corbacioglu, Selim, additional, de la Fuente, Josu, additional, Dhedin, Nathalie, additional, Pondarré, Corinne, additional, Foell, Juergen, additional, O' Boyle, Farah, additional, Lankester, Arjan, additional, Calore, Elisabetta, additional, Varotto, Stefania, additional, Zecca, Marco, additional, Al-Seraihy, Amal, additional, Aljurf, Mahmoud, additional, Fasth, Anders, additional, Bonanomi, Sonia, additional, Addari, Maria Carmen, additional, Locatelli, Franco, additional, Ferster, Alina, additional, Labarque, Veerle, additional, Bader, Peter, additional, Simões, Belinda Pinto, additional, Tozatto-Maio, Karina, additional, Rocha, Vanderson, additional, Kuentz, Mathieu, additional, Elayoubi, Hanadi, additional, Ruggeri, Annalisa, additional, Bernaudin, Francoise, additional, and Gluckman, Eliane, additional

Published
2018
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50. Invasive mucormycosis in children with cancer: A retrospective study from the Infection Working Group of Italian Pediatric Hematology Oncology Association

Author

Muggeo, Paola, primary, Calore, Elisabetta, additional, Decembrino, Nunzia, additional, Frenos, Stefano, additional, De Leonardis, Francesco, additional, Colombini, Antonella, additional, Petruzziello, Fara, additional, Perruccio, Katia, additional, Berger, Massimo, additional, Burnelli, Roberta, additional, Zanazzo, Giulio A., additional, Santoro, Nicola, additional, and Cesaro, Simone, additional

Published
2018
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