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5. Metagenomic Sequencing of Monkeypox Virus, Northern Mexico

Author

Galan-Huerta, Kame A., Paz-Infanzon, Manuel, Nuzzolo-Shihadeh, Laura, Ruiz-Higareda, Ali F., Bocanegra-Ibarias, Paola, Villareal-Martinez, Daniel Z., Munoz-Garza, Fania Z., Guerrero-Putz, Maria D., Saenz-Ibarra, Barbara, Barboza-Quintana, Oralia, Ocampo-Candiani, Jorge, Rivas-Estilla, Ana M., and Camacho-Ortiz, Adrian

Subjects
Nucleotide sequencing -- Usage, Human monkeypox -- Causes of, DNA viruses -- Identification and classification -- Genetic aspects, DNA sequencing -- Usage, Health
Abstract

Monkeypox virus (MPXV) is a zoonotic pathogen that causes mpox (formerly monkeypox), a febrile rash disease, in humans. It has caused multiple outbreaks in the past (1) but recently acquired [...]

Published
2023

7. Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial

Author

Ahn, Mi-Young, Akasbi, Miriam, Alatorre-Alexander, Jorge, Altclas, Javier David, Ariel, Federico, Ariza, Horacio Alberto, Atkar, Chandrasekhar, Bertetti, Anselmo, Bhattacharya, Meenakshi, Briones, Maria Luisa, Budhraja, Akshay, Burza, Aaliya, Camacho Ortiz, Adrian, Caricchio, Roberto, Casas, Marcelo, Cevoli Recio, Valeria, Choi, Won Suk, Cohen, Emilia, Comulada-Rivera, Angel, Cook, Paul, Cornejo Juarez, Dora Patricia, Daniel, Carnevali, Degrecci Relvas, Luiz Fernando, Dominguez Cherit, Jose Guillermo, Ellerin, Todd, Enikeev, Dmitry, Erico Tanni Minamoto, Suzana, Estrada, Vicente, Fiss, Elie, Furuichi, Motohiko, Giovanni Luz, Kleber, Goldman, Jason D., Gonzalez, Omar, Gordeev, Ivan, Gruenewald, Thomas, Hamamoto Sato, Victor Augusto, Heo, Eun Young, Heo, Jung Yeon, Hermida, Maria, Hirai, Yuji, Hutchinson, David, Iastrebner, Claudio, Ioachimescu, Octavian, Jain, Manish, Juliani Souza Lima, Maria Patelli, Khan, Akram, Kremer, Andreas E., Lawrie, Thomas, MacElwee, Mark, Madhani-Lovely, Farah, Malhotra, Vinay, Martínez Resendez, Michel Fernando, McKinnell, James, Milligan, Patrick, Minelli, Cesar, Moran Rodriguez, Miguel Angel, Parody, Maria Leonor, Paulin, Priscila, Pellegrini, Rita de Cassia, Pemu, Priscilla, Procopio Carvalho, Ana Carolina, Puoti, Massimo, Purow, Joshua, Ramesh, Mayur, Rea Neto, Alvaro, Robinson, Philip, Rodrigues, Cristhieni, Rojas Velasco, Gustavo, Saraiva, Jose Francisco Kerr, Scheinberg, Morton, Schreiber, Stefan, Scublinsky, Dario, Sevciovic Grumach, Anete, Shawa, Imad, Simon Campos, Jesus, Sofat, Nidhi, Som, Mousumi, Spinner, Christoph D., Sprinz, Eduardo, Stienecker, Roger, Suarez, Jose, Tachikawa, Natsuo, Tahir, Hasan, Tiffany, Brian, Vishnevsky, Alexander, Westheimer Cavalcante, Adilson, Zirpe, Kapil, Marconi, Vincent C, Ramanan, Athimalaipet V, de Bono, Stephanie, Kartman, Cynthia E, Krishnan, Venkatesh, Liao, Ran, Piruzeli, Maria Lucia B, Goldman, Jason D, de Cassia Pellegrini, Rita, Cardoso, Anabela, Chakladar, Sujatro, Crowe, Brenda, Reis, Paulo, Zhang, Xin, Adams, David H, and Ely, E Wesley

Published
2021
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11. Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials

Author

Axfors, Cathrine, Janiaud, Perrine, Schmitt, Andreas M., van’t Hooft, Janneke, Smith, Emily R., Haber, Noah A., Abayomi, Akin, Abduljalil, Manal, Abdulrahman, Abdulkarim, Acosta-Ampudia, Yeny, Aguilar-Guisado, Manuela, Al-Beidh, Farah, Alejandria, Marissa M., Alfonso, Rachelle N., Ali, Mohammad, AlQahtani, Manaf, AlZamrooni, Alaa, Anaya, Juan-Manuel, Ang, Mark Angelo C., Aomar, Ismael F., Argumanis, Luis E., Averyanov, Alexander, Baklaushev, Vladimir P., Balionis, Olga, Benfield, Thomas, Berry, Scott, Birocco, Nadia, Bonifacio, Lynn B., Bowen, Asha C., Bown, Abbie, Cabello-Gutierrez, Carlos, Camacho, Bernardo, Camacho-Ortiz, Adrian, Campbell-Lee, Sally, Cao, Damon H., Cardesa, Ana, Carnate, Jose M., Castillo, German Jr. J., Cavallo, Rossana, Chowdhury, Fazle R., Chowdhury, Forhad U. H., Ciccone, Giovannino, Cingolani, Antonella, Climacosa, Fresthel Monica M., Compernolle, Veerle, Cortez, Carlo Francisco N., Costa Neto, Abel, D’Antico, Sergio, Daly, James, Danielle, Franca, Davis, Joshua S., De Rosa, Francesco Giuseppe, Denholm, Justin T., Denkinger, Claudia M., Desmecht, Daniel, Díaz-Coronado, Juan C., Díaz Ponce-Medrano, Juan A., Donneau, Anne-Françoise, Dumagay, Teresita E., Dunachie, Susanna, Dungog, Cecile C., Erinoso, Olufemi, Escasa, Ivy Mae S., Estcourt, Lise J., Evans, Amy, Evasan, Agnes L. M., Fareli, Christian J., Fernandez-Sanchez, Veronica, Galassi, Claudia, Gallo, Juan E., Garcia, Patricia J., Garcia, Patricia L., Garcia, Jesus A., Garigliany, Mutien, Garza-Gonzalez, Elvira, Gauiran, Deonne Thaddeus V., Gaviria García, Paula A., Giron-Gonzalez, Jose-Antonio, Gómez-Almaguer, David, Gordon, Anthony C., Gothot, André, Grass Guaqueta, Jeser Santiago, Green, Cameron, Grimaldi, David, Hammond, Naomi E., Harvala, Heli, Heralde, Francisco M., Herrick, Jesica, Higgins, Alisa M., Hills, Thomas E., Hines, Jennifer, Holm, Karin, Hoque, Ashraful, Hoste, Eric, Ignacio, Jose M., Ivanov, Alexander V., Janssen, Maike, Jennings, Jeffrey H., Jha, Vivekanand, King, Ruby Anne N., Kjeldsen-Kragh, Jens, Klenerman, Paul, Kotecha, Aditya, Krapp, Fiorella, Labanca, Luciana, Laing, Emma, Landin-Olsson, Mona, Laterre, Pierre-François, Lim, Lyn-Li, Lim, Jodor, Ljungquist, Oskar, Llaca-Díaz, Jorge M., López-Robles, Concepción, López-Cárdenas, Salvador, Lopez-Plaza, Ileana, Lucero, Josephine Anne C., Lundgren, Maria, Macías, Juan, Maganito, Sandy C., Malundo, Anna Flor G., Manrique, Rubén D., Manzini, Paola M., Marcos, Miguel, Marquez, Ignacio, Martínez-Marcos, Francisco Javier, Mata, Ana M., McArthur, Colin J., McQuilten, Zoe K., McVerry, Bryan J., Menon, David K., Meyfroidt, Geert, Mirasol, Ma. Angelina L., Misset, Benoît, Molton, James S., Mondragon, Alric V., Monsalve, Diana M., Moradi Choghakabodi, Parastoo, Morpeth, Susan C., Mouncey, Paul R., Moutschen, Michel, Müller-Tidow, Carsten, Murphy, Erin, Najdovski, Tome, Nichol, Alistair D., Nielsen, Henrik, Novak, Richard M., O’Sullivan, Matthew V. N., Olalla, Julian, Osibogun, Akin, Osikomaiya, Bodunrin, Oyonarte, Salvador, Pardo-Oviedo, Juan M., Patel, Mahesh C., Paterson, David L., Peña-Perez, Carlos A., Perez-Calatayud, Angel A., Pérez-Alba, Eduardo, Perkina, Anastasia, Perry, Naomi, Pouladzadeh, Mandana, Poyato, Inmaculada, Price, David J., Quero, Anne Kristine H., Rahman, Md. M., Rahman, Md. S., Ramesh, Mayur, Ramírez-Santana, Carolina, Rasmussen, Magnus, Rees, Megan A., Rego, Eduardo, Roberts, Jason A., Roberts, David J., Rodríguez, Yhojan, Rodríguez-Baño, Jesús, Rogers, Benjamin A., Rojas, Manuel, Romero, Alberto, Rowan, Kathryn M., Saccona, Fabio, Safdarian, Mehdi, Santos, Maria Clariza M., Sasadeusz, Joe, Scozzari, Gitana, Shankar-Hari, Manu, Sharma, Gorav, Snelling, Thomas, Soto, Alonso, Tagayuna, Pedrito Y., Tang, Amy, Tatem, Geneva, Teofili, Luciana, Tong, Steven Y. C., Turgeon, Alexis F., Veloso, Januario D., Venkatesh, Balasubramanian, Ventura-Enriquez, Yanet, Webb, Steve A., Wiese, Lothar, Wikén, Christian, Wood, Erica M., Yusubalieva, Gaukhar M., Zacharowski, Kai, Zarychanski, Ryan, Khanna, Nina, Moher, David, Goodman, Steven N., Ioannidis, John P. A., and Hemkens, Lars G.

Published
2021
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19. Phenotypic and genotypic characterization of vancomycin-resistant Enterococcus faecium clinical isolates from two hospitals in Mexico: First detection of VanB phenotype-vanA genotype

Author

Bocanegra-Ibarias, Paola, Flores-Treviño, Samantha, Camacho-Ortiz, Adrián, Morfin-Otero, Rayo, Villarreal-Treviño, Licet, Llaca-Díaz, Jorge, Martínez-Landeros, Erik Alan, Rodríguez-Noriega, Eduardo, Calzada-Güereca, Andrés, Maldonado-Garza, Héctor Jesús, and Garza-González, Elvira

Published
2016
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23. Bacterial incidence and drug resistance from pathogens recovered from blood, cerebrospinal and pleural fluids in 2019–2020. Results of the Invifar network

Author

Garza-González, Elvira, primary, Camacho-Ortiz, Adrian, additional, Ponce-de-Leon, Alfredo, additional, Ortiz-Brizuela, Edgar, additional, López-Jácome, Luis Esaú, additional, Colin, Claudia, additional, Rojas-Larios, Fabian, additional, Newton-Sánchez, Oscar A., additional, Echaniz-Aviles, Gabriela, additional, Carnalla-Barajas, Maria Noemi, additional, Soto, Araceli, additional, Bocanegra-Ibarias, Paola, additional, Hernández-Dueñas, Ana María del Rocío, additional, Velázquez-Acosta, María del Consuelo, additional, Avilés-Benítez, Laura Karina, additional, Mena-Ramirez, Juan Pablo, additional, Romero, Daniel, additional, Mora-Jiménez, Isela, additional, Alcaraz-Espejel, Margarita, additional, Feliciano-Guzmán, José Manuel, additional, López-García, Maribel, additional, Rodriguez-Zulueta, Patricia, additional, Quevedo-Ramos, María Angelina, additional, Padilla-Ibarra, Cecilia, additional, Couoh-May, Carlos Antonio, additional, Rivera-Ferreira, Maria Carolina, additional, Morales-de-la-Peña, Cecilia Teresita, additional, Zubiate, Hector, additional, Peralta-Catalán, Raúl, additional, Cetina-Umaña, Carlos Miguel, additional, Rincón-Zuno, Joaquin, additional, Perez-Ricardez, Maria Lucia, additional, Hernández-Cordova, Iris Yazmin, additional, López-Gutiérrez, Eduardo, additional, Gil, Mariana, additional, Aguirre-Burciaga, Efren, additional, Huirache-Villalobos, Guadalupe Soledad, additional, Munoz, Scarlett, additional, Barlandas-Rendón, Nicolás Rogelio Eric, additional, Bolado-Martinez, Enrique, additional, Quintanilla-Cazares, Luis Javier, additional, Gómez-Choel, Abraham C., additional, Lopez, Laura, additional, Tinoco, Juan Carlos, additional, Martínez-Gamboa, Rosa Areli, additional, Molina, Alejandro, additional, Escalante-Armenta, Samuel Pavel, additional, Duarte, Lizbeth, additional, Ruiz-Gamboa, Luis Alberto, additional, Cobos-Canul, Dulce Isabel, additional, López, Dulce, additional, Barroso-Herrera-y-Cairo, Irma Elena, additional, Rodriguez-Noriega, Eduardo, additional, and Morfin-Otero, Rayo, additional

Published
2023
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26. The global case fatality rate of coronavirus disease 2019 by continents and national income: A meta-analysis

Author

Abou Ghayda, Ramy, Lee, Keum Hwa, Han, Young Joo, Ryu, Seohyun, Hong, Sung Hwi, Yoon, Sojung, Jeong, Gwang Hum, Yang, Jae Won, Lee, Hyo Jeong, Lee, Jinhee, Lee, Jun Young, Effenberger, Maria, Eisenhut, Michael, Kronbichler, Andreas, Solmi, Marco, Li, Han, Jacob, Louis, Koyanagi, Ai, Radua, Joaquim, Park, Myung Bae, Aghayeva, Sevda, Ahmed, Mohamed L. C. B., Al Serouri, Abdulwahed, Al-Shamsi, Humaid O., Amir-Behghadami, Mehrdad, Baatarkhuu, Oidov, Bashour, Hyam, Bondarenko, Anastasiia, Camacho-Ortiz, Adrian, Castro, Franz, Cox, Horace, Davtyan, Hayk, Douglas, Kirk, Dragioti, Elena, Ebrahim, Shahul, Ferioli, Martina, Harapan, Harapan, Mallah, Saad I, Ikram, Aamer, Inoue, Shigeru, Jankovic, Slobodan, Jayarajah, Umesh, Jesenak, Milos, Kakodkar, Pramath, Kebede, Yohannes, Kifle, Meron, Koh, David, Males, Visnja K., Kotfis, Katarzyna, Lakoh, Sulaiman, Ling, Lowell, Llibre-Guerra, Jorge, Machida, Masaki, Makurumidze, Richard, Mamun, Mohammed, Masic, Izet, Van Minh, Hoang, Moiseev, Sergey, Nadasdy, Thomas, Nahshon, Chen, Namendys-Silva, Silvio A., Yongsi, Blaise N., Nielsen, Henning B., Nodjikouambaye, Zita A., Ohnmar, Ohnmar, Oksanen, Atte, Owopetu, Oluwatomi, Parperis, Konstantinos, Perez, Gonzalo E., Pongpirul, Krit, Rademaker, Marius, Rosa, Sandro, Sah, Ranjit, Sallam, Dina, Schober, Patrick, Singhal, Tanu, Tafaj, Silva, Torres, Irene, Smith Torres-Roman, J., Tsartsalis, Dimitrios, Tsolmon, Jadamba, Tuychiev, Laziz, Vukcevic, Batric, Wanghi, Guy, Wollina, Uwe, Xu, Ren-He, Yang, Lin, Zaidi, Zoubida, Smith, Lee, Shin, Jae Il, Abou Ghayda, Ramy, Lee, Keum Hwa, Han, Young Joo, Ryu, Seohyun, Hong, Sung Hwi, Yoon, Sojung, Jeong, Gwang Hum, Yang, Jae Won, Lee, Hyo Jeong, Lee, Jinhee, Lee, Jun Young, Effenberger, Maria, Eisenhut, Michael, Kronbichler, Andreas, Solmi, Marco, Li, Han, Jacob, Louis, Koyanagi, Ai, Radua, Joaquim, Park, Myung Bae, Aghayeva, Sevda, Ahmed, Mohamed L. C. B., Al Serouri, Abdulwahed, Al-Shamsi, Humaid O., Amir-Behghadami, Mehrdad, Baatarkhuu, Oidov, Bashour, Hyam, Bondarenko, Anastasiia, Camacho-Ortiz, Adrian, Castro, Franz, Cox, Horace, Davtyan, Hayk, Douglas, Kirk, Dragioti, Elena, Ebrahim, Shahul, Ferioli, Martina, Harapan, Harapan, Mallah, Saad I, Ikram, Aamer, Inoue, Shigeru, Jankovic, Slobodan, Jayarajah, Umesh, Jesenak, Milos, Kakodkar, Pramath, Kebede, Yohannes, Kifle, Meron, Koh, David, Males, Visnja K., Kotfis, Katarzyna, Lakoh, Sulaiman, Ling, Lowell, Llibre-Guerra, Jorge, Machida, Masaki, Makurumidze, Richard, Mamun, Mohammed, Masic, Izet, Van Minh, Hoang, Moiseev, Sergey, Nadasdy, Thomas, Nahshon, Chen, Namendys-Silva, Silvio A., Yongsi, Blaise N., Nielsen, Henning B., Nodjikouambaye, Zita A., Ohnmar, Ohnmar, Oksanen, Atte, Owopetu, Oluwatomi, Parperis, Konstantinos, Perez, Gonzalo E., Pongpirul, Krit, Rademaker, Marius, Rosa, Sandro, Sah, Ranjit, Sallam, Dina, Schober, Patrick, Singhal, Tanu, Tafaj, Silva, Torres, Irene, Smith Torres-Roman, J., Tsartsalis, Dimitrios, Tsolmon, Jadamba, Tuychiev, Laziz, Vukcevic, Batric, Wanghi, Guy, Wollina, Uwe, Xu, Ren-He, Yang, Lin, Zaidi, Zoubida, Smith, Lee, and Shin, Jae Il

Abstract

The aim of this study is to provide a more accurate representation of COVID-19s case fatality rate (CFR) by performing meta-analyses by continents and income, and by comparing the result with pooled estimates. We used multiple worldwide data sources on COVID-19 for every country reporting COVID-19 cases. On the basis of data, we performed random and fixed meta-analyses for CFR of COVID-19 by continents and income according to each individual calendar date. CFR was estimated based on the different geographical regions and levels of income using three models: pooled estimates, fixed- and random-model. In Asia, all three types of CFR initially remained approximately between 2.0% and 3.0%. In the case of pooled estimates and the fixed model results, CFR increased to 4.0%, by then gradually decreasing, while in the case of random-model, CFR remained under 2.0%. Similarly, in Europe, initially, the two types of CFR peaked at 9.0% and 10.0%, respectively. The random-model results showed an increase near 5.0%. In high-income countries, pooled estimates and fixed-model showed gradually increasing trends with a final pooled estimates and random-model reached about 8.0% and 4.0%, respectively. In middle-income, the pooled estimates and fixed-model have gradually increased reaching up to 4.5%. in low-income countries, CFRs remained similar between 1.5% and 3.0%. Our study emphasizes that COVID-19 CFR is not a fixed or static value. Rather, it is a dynamic estimate that changes with time, population, socioeconomic factors, and the mitigatory efforts of individual countries.

Published
2022
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29. Correction to: Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members

Author

Reichert, Martin, Sartelli, Massimo, Weigand, Markus A., Hecker, Matthias, Oppelt, Philip U., Noll, Julia, Askevold, Ingolf H., Liese, Juliane, Padberg, Winfried, Coccolini, Federico, Catena, Fausto, Hecker, Andreas, Peckham-Cooper, Adam, Camacho-Ortiz, Adrian, Mastoraki, Aikaterini T., Landaluce-Olavarria, Aitor, Pal, Ajay Kumar, Kuriyama, Akira, Chichom-Mefire, Alain, Porcu, Alberto, Martínez-Pérez, Aleix, Karamarkovic, Aleksandar R., Osipov, Aleksei V., Coppola, Alessandro, Cucchetti, Alessandro, Spolini, Alessandro, Giordano, Alessio, Reinisch-Liese, Alexander, Kavalakat, Alfie J., Vasilescu, Alin, Alamin, Amin, Gupta, Amit, Dascalu, Ana Maria, Musina, Ana-Maria, Bakopoulos, Anargyros, Zakaria, Andee Dzulkarnaen, Vereczkei, Andras, Balla, Andrea, Bottari, Andrea, Baumann, Andreas, Fette, Andreas, Litvin, Andrey, Reichert, Aniella Katharina, Guariniello, Anna, Paspala, Anna, Schneck, Anne-Sophie, Brillantino, Antonio, Pesce, Antonio, Isik, Arda, Leppäniemi, Ari Kalevi, Papadopoulos, Aristeidis, Kechagias, Aristotelis, Mohamed, Ashraf Yehya Abdalla, Mitul, Ashrarur Rahman, Marinis, Athanasios, Syllaios, Athanasios, Mantoglu, Baris, De Simone, Belinda, Weiss, Benjamin Stefan, Pösentrup, Bernd, Picardi, Biagio, Zampogna, Biagio, Sakakushev, Boris Eugeniev, Atanasov, Boyko Chavdarov, Nardo, Bruno, Calik, Bulent, Cremonini, Camilla, Ordoñez, Carlos A., Seretis, Charalampos, Cascone, Chiara, Chouliaras, Christos, Bendinelli, Cino, Lopes, Claudia, Guerci, Claudio, Weber, Clemens, Nastos, Constantinos, Mesina, Cristian, Caputo, Damiano, Massalou, Damien, Cavaliere, Davide, Mcnamara, Deborah A., Demetriades, Demetrios, Pantalone, Desirè, Coletta, Diego, Sasia, Diego, Visconti, Diego, Weber, Dieter G., Corallino, Diletta, Chatzipetris, Dimitrios, Manatakis, Dimitrios K., Ntourakis, Dimitrios, Papaconstantinou, Dimitrios, Schizas, Dimitrios, Chrysikos, Dimosthenis, Adamovich, Dmitry Mikhailovich, Elkafrawy, Doaa, Seban, Dragos, García, Edgar Fernando Hernandez, Baldini, Edoardo, Picetti, Edoardo, Tan, Edward C. T. H., Baili, Efstratia, Lostoridis, Eftychios, Toma, Elena Adelina, Colak, Elif, Cerutti, Elisabetta, Steyn, Elmin, Hsabo, Elmuiz A., Kapetanakis, Emmanouil Ioannis, Kaouras, Emmanouil, Schneck, Emmanuel, Akin, Emrah, Gonullu, Emre, Çelik, Enes, Cicuttin, Enrico, Pinotti, Enrico, Johnsson, Erik, Moore, Ernest E., Agastra, Ervis, Dimitrov, Evgeni Nikolaev, Griffiths, Ewen A., D’Acapito, Fabrizio, Saraceno, Federica, Alconchel, Felipe, Zeppernick, Felix Alexander, Rodríguez, Fernando Machado, Abu-Zidan, Fikri, Pecchini, Francesca, Favi, Francesco, Ferrara, Francesco, Fleres, Francesco, Pata, Francesco, Roscio, Francesco Pietro Maria, Mulita, Francesk, Dor, Frank J. M. F., Linder, Fredrik, Dimofte, Gabriel, Rodrigues, Gabriel, Nita, Gabriela, Sganga, Gabriele, Martines, Gennaro, Mazzarella, Gennaro, Perrone, Gennaro, Velmahos, George, Lianos, Georgios D., Tomadze, Gia, Baiocchi, Gian Luca, D’Ambrosio, Giancarlo, Pellino, Gianluca, Pattacini, Gianmaria Casoni, Giraudo, Giorgio, Lisi, Giorgio, Tebala, Giovanni Domenico, Pirozzolo, Giovanni, Montori, Giulia, Argenio, Giulio, Brisinda, Giuseppe, Currò, Giuseppe, Giuliani, Giuseppe, Palomba, Giuseppe, Roscitano, Giuseppe, Avşar, Gökhan, Augustin, Goran, Clarizia, Guglielmo, Vega, Gustavo M. Machain, Fraga, Gustavo P., Sethi, Harsheet, Eltyeb, Hazim Abdulnassir, Lohse, Helmut A. Segovia, Lohse, Herald René Segovia, Bayhan, Hüseyin, Hamid, Hytham K. S., Kryvoruchko, Igor A., Iannone, Immacolata, Wani, Imtiaz, Lazaridis, Ioannis I., Katsaros, Ioannis, Nikolopoulos, Ioannis, Negoi, Ionut, Reccia, Isabella, Di Carlo, Isidoro, Olaoye, Iyiade Olatunde, Czepiel, Jacek, Kim, Jae Il, Meyer, Jeremy, Terrazas, Jesus Manuel Saenz, Tochie, Joel Noutakdie, Galante, Joseph M., Davies, Justin, Sugand, Kapil, Gonfa, Kebebe Bekele, Rasa, Kemal, Kok, Kenneth Y. Y., Apostolou, Konstantinos G., Lasithiotakis, Konstantinos, Tsekouras, Konstantinos, Angamuthu, Kumar, Akhmeteli, Lali, Sydorchuk, Larysa, Fortuna, Laura, Siragusa, Leandro, Pagani, Leonardo, Solaini, Leonardo, Miller, Lisa A., Bains, Lovenish, Ansaloni, Luca, Ferrario, Luca, Bonavina, Luigi, Conti, Luigi, Buonomo, Luis Antonio, Tallon-Aguilar, Luis, Tomczyk, Lukas, Widmer, Lukas Werner, Walędziak, Maciej, Gachabayov, Mahir, Bulanauca, Maloni M., Malbrain, Manu L. N. G., Maegele, Marc, Catarci, Marco, Ceresoli, Marco, Ranucci, Maria Chiara, Antonopoulou, Maria Ioanna, Papadoliopoulou, Maria, Valenti, Maria Rosaria, Sotiropoulou, Maria, D’Oria, Mario, Martín, Mario Serradilla, Hirschburger, Markus, Veroux, Massimiliano, Fantoni, Massimo, Nardi, Matteo, Tolonen, Matti, Montuori, Mauro, Podda, Mauro, Scheiterle, Maximilian, Frountzas, Maximos, Sarıkaya, Mehmet, Yildirim, Mehmet, Bender, Michael, Vailas, Michail, Teuben, Michel, Campanelli, Michela, Ammendola, Michele, Malerba, Michele, Pisano, Michele, Pertea, Mihaela, Slavchev, Mihail, Ukkonen, Mika, Bala, Miklosh, Chirica, Mircea, Barone, Mirko, Shaat, Mohamed Maher, Mohammed, Mohammed Jibreel Suliman, Abuelgasim, Mona Awad Akasha, Gureh, Monika, Ouadii, Mouaqit, Balkan, Mujdat, Mohamed, Mumin, Hakseven, Musluh, Velenciuc, Natalia, Cillara, Nicola, De’Angelis, Nicola, Tamini, Nicolò, Zavras, Nikolaos J., Machairas, Nikolaos, Michalopoulos, Nikolaos, Koliakos, Nikolaos N., Pararas, Nikolaos, Donlon, Noel E., Medappil, Noushif, Ben-Ishay, Offir, Stefano, Olmi, Islam, Omar, Tammo, Ömer, Ioannidis, Orestis, Aparicio, Oscar, Baraket, Oussama, Kumar, Pankaj, Cianci, Pasquale, Örtenwall, Per, Uchikov, Petar Angelov, de Reuver, Philip, Stahel, Philip F., Barie, Philip S., Piccoli, Micaela, Major, Piotr, Navsaria, Pradeep H., Sasmal, Prakash Kumar, Coimbra, Raul, Rahim, Razrim, Çapoğlu, Recayi, Koshy, Renol M., Gonsaga, Ricardo Alessandro Teixeira, Pertile, Riccardo, Mohamed, Rifat Ramadan Mussa, Deryol, Rıza, Sawyer, Robert G., Angelico, Roberta, Ragozzino, Roberta, Bini, Roberto, Cammarata, Roberto, Scaramuzzo, Rosa, Gioco, Rossella, Sydorchuk, Ruslan, Ahmed, Salma, Di Saverio, Salomone, Emile, Sameh Hany, Delibegovic, Samir, Marwah, Sanjay, Symeonidis, Savvas, Thomas, Scott G., Demir, Sebahattin, Awad, Selmy S., Atici, Semra Demirli, Chooklin, Serge, Meric, Serhat, Sarıkaya, Sevcan, Chowdhury, Sharfuddin, Mirghani, Shaza Faycal, Wren, Sherry M., Gargarella, Simone, Del Monte, Simone Rossi, Esposito, Sofia, Xenaki, Sofia, Mohamed, Soliman Fayez Ghedan, Beka, Solomon Gurmu, Lunca, Sorinel, Delis, Spiros G., Dritsas, Spyridon, Morarasu, Stefan, Magnone, Stefano, Rossi, Stefano, Bitsianis, Stefanos, Kykalos, Stylianos, Baral, Suman, Jain, Sumita A., Ali, Syed Muhammad, Pintar, Tadeja, Triantafyllou, Tania, Delko, Tarik, Perra, Teresa, Sidiropoulos, Theodoros A., Scalea, Thomas M., Vilz, Tim Oliver, Hardcastle, Timothy Craig, Wannatoop, Tongporn, Herzog, Torsten, Mishra, Tushar Subhadarshan, Boggi, Ugo, Calu, Valentin, Tomajer, Valentina, Agnoletti, Vanni, Lohsiriwat, Varut, Kong, Victor, Muñoz-Cruzado, Virginia Durán, Shelat, Vishal G., Khokha, Vladimir, Ghannam, Wagih Mommtaz, Biffl, Walter L., Zuidema, Wietse, Kara, Yasin, Kobe, Yoshiro, Demetrashvili, Zaza, Memish, Ziad A., Madrazo, Zoilo, Balogh, Zsolt J., and Bayhan, Zulfu

Subjects
Emergency Medicine, Surgery
Published
2022

31. The global case fatality rate of coronavirus disease 2019 by continents and national income: A meta‐analysis

Author

Abou Ghayda, Ramy, primary, Lee, Keum Hwa, additional, Han, Young Joo, additional, Ryu, Seohyun, additional, Hong, Sung Hwi, additional, Yoon, Sojung, additional, Jeong, Gwang Hum, additional, Yang, Jae Won, additional, Lee, Hyo Jeong, additional, Lee, Jinhee, additional, Lee, Jun Young, additional, Effenberger, Maria, additional, Eisenhut, Michael, additional, Kronbichler, Andreas, additional, Solmi, Marco, additional, Li, Han, additional, Jacob, Louis, additional, Koyanagi, Ai, additional, Radua, Joaquim, additional, Park, Myung Bae, additional, Aghayeva, Sevda, additional, Ahmed, Mohamed L. C. B., additional, Al Serouri, Abdulwahed, additional, Al‐Shamsi, Humaid O., additional, Amir‐Behghadami, Mehrdad, additional, Baatarkhuu, Oidov, additional, Bashour, Hyam, additional, Bondarenko, Anastasiia, additional, Camacho‐Ortiz, Adrian, additional, Castro, Franz, additional, Cox, Horace, additional, Davtyan, Hayk, additional, Douglas, Kirk, additional, Dragioti, Elena, additional, Ebrahim, Shahul, additional, Ferioli, Martina, additional, Harapan, Harapan, additional, Mallah, Saad I., additional, Ikram, Aamer, additional, Inoue, Shigeru, additional, Jankovic, Slobodan, additional, Jayarajah, Umesh, additional, Jesenak, Milos, additional, Kakodkar, Pramath, additional, Kebede, Yohannes, additional, Kifle, Meron, additional, Koh, David, additional, Males, Visnja K., additional, Kotfis, Katarzyna, additional, Lakoh, Sulaiman, additional, Ling, Lowell, additional, Llibre‐Guerra, Jorge, additional, Machida, Masaki, additional, Makurumidze, Richard, additional, Mamun, Mohammed A., additional, Masic, Izet, additional, Van Minh, Hoang, additional, Moiseev, Sergey, additional, Nadasdy, Thomas, additional, Nahshon, Chen, additional, Ñamendys‐Silva, Silvio A., additional, Yongsi, Blaise N., additional, Nielsen, Henning B., additional, Nodjikouambaye, Zita A., additional, Ohnmar, Ohnmar, additional, Oksanen, Atte, additional, Owopetu, Oluwatomi, additional, Parperis, Konstantinos, additional, Perez, Gonzalo E., additional, Pongpirul, Krit, additional, Rademaker, Marius, additional, Rosa, Sandro, additional, Sah, Ranjit, additional, Sallam, Dina, additional, Schober, Patrick, additional, Singhal, Tanu, additional, Tafaj, Silva, additional, Torres, Irene, additional, Torres‐Roman, J. Smith, additional, Tsartsalis, Dimitrios, additional, Tsolmon, Jadamba, additional, Tuychiev, Laziz, additional, Vukcevic, Batric, additional, Wanghi, Guy, additional, Wollina, Uwe, additional, Xu, Ren‐He, additional, Yang, Lin, additional, Zaidi, Zoubida, additional, Smith, Lee, additional, and Shin, Jae Il, additional

Published
2022
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32. Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial

Author

Marconi, Vincent C, primary, Ramanan, Athimalaipet V, additional, de Bono, Stephanie, additional, Kartman, Cynthia E, additional, Krishnan, Venkatesh, additional, Liao, Ran, additional, Piruzeli, Maria Lucia B, additional, Goldman, Jason D, additional, Alatorre-Alexander, Jorge, additional, de Cassia Pellegrini, Rita, additional, Estrada, Vicente, additional, Som, Mousumi, additional, Cardoso, Anabela, additional, Chakladar, Sujatro, additional, Crowe, Brenda, additional, Reis, Paulo, additional, Zhang, Xin, additional, Adams, David H, additional, Ely, E Wesley, additional, Ahn, Mi-Young, additional, Akasbi, Miriam, additional, Altclas, Javier David, additional, Ariel, Federico, additional, Ariza, Horacio Alberto, additional, Atkar, Chandrasekhar, additional, Bertetti, Anselmo, additional, Bhattacharya, Meenakshi, additional, Briones, Maria Luisa, additional, Budhraja, Akshay, additional, Burza, Aaliya, additional, Camacho Ortiz, Adrian, additional, Caricchio, Roberto, additional, Casas, Marcelo, additional, Cevoli Recio, Valeria, additional, Choi, Won Suk, additional, Cohen, Emilia, additional, Comulada-Rivera, Angel, additional, Cook, Paul, additional, Cornejo Juarez, Dora Patricia, additional, Daniel, Carnevali, additional, Degrecci Relvas, Luiz Fernando, additional, Dominguez Cherit, Jose Guillermo, additional, Ellerin, Todd, additional, Enikeev, Dmitry, additional, Erico Tanni Minamoto, Suzana, additional, Fiss, Elie, additional, Furuichi, Motohiko, additional, Giovanni Luz, Kleber, additional, Goldman, Jason D., additional, Gonzalez, Omar, additional, Gordeev, Ivan, additional, Gruenewald, Thomas, additional, Hamamoto Sato, Victor Augusto, additional, Heo, Eun Young, additional, Heo, Jung Yeon, additional, Hermida, Maria, additional, Hirai, Yuji, additional, Hutchinson, David, additional, Iastrebner, Claudio, additional, Ioachimescu, Octavian, additional, Jain, Manish, additional, Juliani Souza Lima, Maria Patelli, additional, Khan, Akram, additional, Kremer, Andreas E., additional, Lawrie, Thomas, additional, MacElwee, Mark, additional, Madhani-Lovely, Farah, additional, Malhotra, Vinay, additional, Martínez Resendez, Michel Fernando, additional, McKinnell, James, additional, Milligan, Patrick, additional, Minelli, Cesar, additional, Moran Rodriguez, Miguel Angel, additional, Parody, Maria Leonor, additional, Paulin, Priscila, additional, Pellegrini, Rita de Cassia, additional, Pemu, Priscilla, additional, Procopio Carvalho, Ana Carolina, additional, Puoti, Massimo, additional, Purow, Joshua, additional, Ramesh, Mayur, additional, Rea Neto, Alvaro, additional, Robinson, Philip, additional, Rodrigues, Cristhieni, additional, Rojas Velasco, Gustavo, additional, Saraiva, Jose Francisco Kerr, additional, Scheinberg, Morton, additional, Schreiber, Stefan, additional, Scublinsky, Dario, additional, Sevciovic Grumach, Anete, additional, Shawa, Imad, additional, Simon Campos, Jesus, additional, Sofat, Nidhi, additional, Spinner, Christoph D., additional, Sprinz, Eduardo, additional, Stienecker, Roger, additional, Suarez, Jose, additional, Tachikawa, Natsuo, additional, Tahir, Hasan, additional, Tiffany, Brian, additional, Vishnevsky, Alexander, additional, Westheimer Cavalcante, Adilson, additional, and Zirpe, Kapil, additional

Published
2021
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33. 1014. Effect of Levofloxaclin and Trimethoprim-sulfamethoxazole on Planktonic and Biofilm Cells of Stenotrophomonas maltophilia Isolates Obtained from Blood and Respiratory Samples

Author

Del Río-Chacón, José Mauricio, primary, Rojas-Larios, Fabian, additional, Villarreal-Salazar, Verónica, additional, Ibarías, Paola Bocanegra, additional, Newton-Sanchez, Oscar Alberto, additional, Camacho-Ortiz, Adrian, additional, and Flores-Treviño, Samantha, additional

Published
2021
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34. Association between convalescent plasma treatment and mortality in COVID-19:a collaborative systematic review and meta-analysis of randomized clinical trials

Author

Axfors, Cathrine, Janiaud, Perrine, Schmitt, Andreas M., van’t Hooft, Janneke, Smith, Emily R., Haber, Noah A., Abayomi, Akin, Abduljalil, Manal, Abdulrahman, Abdulkarim, Acosta-Ampudia, Yeny, Aguilar-Guisado, Manuela, Al-Beidh, Farah, Alejandria, Marissa M., Alfonso, Rachelle N., Ali, Mohammad, AlQahtani, Manaf, AlZamrooni, Alaa, Anaya, Juan Manuel, Ang, Mark Angelo C., Aomar, Ismael F., Argumanis, Luis E., Averyanov, Alexander, Baklaushev, Vladimir P., Balionis, Olga, Benfield, Thomas, Berry, Scott, Birocco, Nadia, Bonifacio, Lynn B., Bowen, Asha C., Bown, Abbie, Cabello-Gutierrez, Carlos, Camacho, Bernardo, Camacho-Ortiz, Adrian, Campbell-Lee, Sally, Cao, Damon H., Cardesa, Ana, Carnate, Jose M., Castillo, German Jr J., Cavallo, Rossana, Chowdhury, Fazle R., Chowdhury, Forhad U.H., Ciccone, Giovannino, Cingolani, Antonella, Climacosa, Fresthel Monica M., Compernolle, Veerle, Cortez, Carlo Francisco N., Costa Neto, Abel, D’Antico, Sergio, Daly, James, Danielle, Franca, Davis, Joshua S., De Rosa, Francesco Giuseppe, Denholm, Justin T., Denkinger, Claudia M., Desmecht, Daniel, Díaz-Coronado, Juan C., Díaz Ponce-Medrano, Juan A., Donneau, Anne Françoise, Dumagay, Teresita E., Dunachie, Susanna, Dungog, Cecile C., Erinoso, Olufemi, Escasa, Ivy Mae S., Estcourt, Lise J., Evans, Amy, Evasan, Agnes L.M., Fareli, Christian J., Fernandez-Sanchez, Veronica, Galassi, Claudia, Gallo, Juan E., Garcia, Patricia J., Garcia, Patricia L., Garcia, Jesus A., Garigliany, Mutien, Garza-Gonzalez, Elvira, Gauiran, Deonne Thaddeus V., Gaviria García, Paula A., Giron-Gonzalez, Jose Antonio, Gómez-Almaguer, David, Gordon, Anthony C., Gothot, André, Grass Guaqueta, Jeser Santiago, Green, Cameron, Grimaldi, David, Hammond, Naomi E., Harvala, Heli, Heralde, Francisco M., Herrick, Jesica, Higgins, Alisa M., Hills, Thomas E., Hines, Jennifer, Holm, Karin, Hoque, Ashraful, Hoste, Eric, Ignacio, Jose M., Ivanov, Alexander V., Janssen, Maike, Jennings, Jeffrey H., Jha, Vivekanand, King, Ruby Anne N., Kjeldsen-Kragh, Jens, Klenerman, Paul, Kotecha, Aditya, Krapp, Fiorella, Labanca, Luciana, Laing, Emma, Landin-Olsson, Mona, Laterre, Pierre François, Lim, Lyn Li, Lim, Jodor, Ljungquist, Oskar, Llaca-Díaz, Jorge M., López-Robles, Concepción, López-Cárdenas, Salvador, Lopez-Plaza, Ileana, Lucero, Josephine Anne C., Lundgren, Maria, Macías, Juan, Maganito, Sandy C., Malundo, Anna Flor G., Manrique, Rubén D., Manzini, Paola M., Marcos, Miguel, Marquez, Ignacio, Martínez-Marcos, Francisco Javier, Mata, Ana M., McArthur, Colin J., McQuilten, Zoe K., McVerry, Bryan J., Menon, David K., Meyfroidt, Geert, Mirasol, Ma Angelina L., Misset, Benoît, Molton, James S., Mondragon, Alric V., Monsalve, Diana M., Moradi Choghakabodi, Parastoo, Morpeth, Susan C., Mouncey, Paul R., Moutschen, Michel, Müller-Tidow, Carsten, Murphy, Erin, Najdovski, Tome, Nichol, Alistair D., Nielsen, Henrik, Novak, Richard M., O’Sullivan, Matthew V.N., Olalla, Julian, Osibogun, Akin, Osikomaiya, Bodunrin, Oyonarte, Salvador, Pardo-Oviedo, Juan M., Patel, Mahesh C., Paterson, David L., Peña-Perez, Carlos A., Perez-Calatayud, Angel A., Pérez-Alba, Eduardo, Perkina, Anastasia, Perry, Naomi, Pouladzadeh, Mandana, Poyato, Inmaculada, Price, David J., Quero, Anne Kristine H., Rahman, Md M., Rahman, Md S., Ramesh, Mayur, Ramírez-Santana, Carolina, Rasmussen, Magnus, Rees, Megan A., Rego, Eduardo, Roberts, Jason A., Roberts, David J., Rodríguez, Yhojan, Rodríguez-Baño, Jesús, Rogers, Benjamin A., Rojas, Manuel, Romero, Alberto, Rowan, Kathryn M., Saccona, Fabio, Safdarian, Mehdi, Santos, Maria Clariza M., Sasadeusz, Joe, Scozzari, Gitana, Shankar-Hari, Manu, Sharma, Gorav, Snelling, Thomas, Soto, Alonso, Tagayuna, Pedrito Y., Tang, Amy, Tatem, Geneva, Teofili, Luciana, Tong, Steven Y.C., Turgeon, Alexis F., Veloso, Januario D., Venkatesh, Balasubramanian, Ventura-Enriquez, Yanet, Webb, Steve A., Wiese, Lothar, Wikén, Christian, Wood, Erica M., Yusubalieva, Gaukhar M., Zacharowski, Kai, Zarychanski, Ryan, Khanna, Nina, Moher, David, Goodman, Steven N., Ioannidis, John P.A., Hemkens, Lars G., Axfors, Cathrine, Janiaud, Perrine, Schmitt, Andreas M., van’t Hooft, Janneke, Smith, Emily R., Haber, Noah A., Abayomi, Akin, Abduljalil, Manal, Abdulrahman, Abdulkarim, Acosta-Ampudia, Yeny, Aguilar-Guisado, Manuela, Al-Beidh, Farah, Alejandria, Marissa M., Alfonso, Rachelle N., Ali, Mohammad, AlQahtani, Manaf, AlZamrooni, Alaa, Anaya, Juan Manuel, Ang, Mark Angelo C., Aomar, Ismael F., Argumanis, Luis E., Averyanov, Alexander, Baklaushev, Vladimir P., Balionis, Olga, Benfield, Thomas, Berry, Scott, Birocco, Nadia, Bonifacio, Lynn B., Bowen, Asha C., Bown, Abbie, Cabello-Gutierrez, Carlos, Camacho, Bernardo, Camacho-Ortiz, Adrian, Campbell-Lee, Sally, Cao, Damon H., Cardesa, Ana, Carnate, Jose M., Castillo, German Jr J., Cavallo, Rossana, Chowdhury, Fazle R., Chowdhury, Forhad U.H., Ciccone, Giovannino, Cingolani, Antonella, Climacosa, Fresthel Monica M., Compernolle, Veerle, Cortez, Carlo Francisco N., Costa Neto, Abel, D’Antico, Sergio, Daly, James, Danielle, Franca, Davis, Joshua S., De Rosa, Francesco Giuseppe, Denholm, Justin T., Denkinger, Claudia M., Desmecht, Daniel, Díaz-Coronado, Juan C., Díaz Ponce-Medrano, Juan A., Donneau, Anne Françoise, Dumagay, Teresita E., Dunachie, Susanna, Dungog, Cecile C., Erinoso, Olufemi, Escasa, Ivy Mae S., Estcourt, Lise J., Evans, Amy, Evasan, Agnes L.M., Fareli, Christian J., Fernandez-Sanchez, Veronica, Galassi, Claudia, Gallo, Juan E., Garcia, Patricia J., Garcia, Patricia L., Garcia, Jesus A., Garigliany, Mutien, Garza-Gonzalez, Elvira, Gauiran, Deonne Thaddeus V., Gaviria García, Paula A., Giron-Gonzalez, Jose Antonio, Gómez-Almaguer, David, Gordon, Anthony C., Gothot, André, Grass Guaqueta, Jeser Santiago, Green, Cameron, Grimaldi, David, Hammond, Naomi E., Harvala, Heli, Heralde, Francisco M., Herrick, Jesica, Higgins, Alisa M., Hills, Thomas E., Hines, Jennifer, Holm, Karin, Hoque, Ashraful, Hoste, Eric, Ignacio, Jose M., Ivanov, Alexander V., Janssen, Maike, Jennings, Jeffrey H., Jha, Vivekanand, King, Ruby Anne N., Kjeldsen-Kragh, Jens, Klenerman, Paul, Kotecha, Aditya, Krapp, Fiorella, Labanca, Luciana, Laing, Emma, Landin-Olsson, Mona, Laterre, Pierre François, Lim, Lyn Li, Lim, Jodor, Ljungquist, Oskar, Llaca-Díaz, Jorge M., López-Robles, Concepción, López-Cárdenas, Salvador, Lopez-Plaza, Ileana, Lucero, Josephine Anne C., Lundgren, Maria, Macías, Juan, Maganito, Sandy C., Malundo, Anna Flor G., Manrique, Rubén D., Manzini, Paola M., Marcos, Miguel, Marquez, Ignacio, Martínez-Marcos, Francisco Javier, Mata, Ana M., McArthur, Colin J., McQuilten, Zoe K., McVerry, Bryan J., Menon, David K., Meyfroidt, Geert, Mirasol, Ma Angelina L., Misset, Benoît, Molton, James S., Mondragon, Alric V., Monsalve, Diana M., Moradi Choghakabodi, Parastoo, Morpeth, Susan C., Mouncey, Paul R., Moutschen, Michel, Müller-Tidow, Carsten, Murphy, Erin, Najdovski, Tome, Nichol, Alistair D., Nielsen, Henrik, Novak, Richard M., O’Sullivan, Matthew V.N., Olalla, Julian, Osibogun, Akin, Osikomaiya, Bodunrin, Oyonarte, Salvador, Pardo-Oviedo, Juan M., Patel, Mahesh C., Paterson, David L., Peña-Perez, Carlos A., Perez-Calatayud, Angel A., Pérez-Alba, Eduardo, Perkina, Anastasia, Perry, Naomi, Pouladzadeh, Mandana, Poyato, Inmaculada, Price, David J., Quero, Anne Kristine H., Rahman, Md M., Rahman, Md S., Ramesh, Mayur, Ramírez-Santana, Carolina, Rasmussen, Magnus, Rees, Megan A., Rego, Eduardo, Roberts, Jason A., Roberts, David J., Rodríguez, Yhojan, Rodríguez-Baño, Jesús, Rogers, Benjamin A., Rojas, Manuel, Romero, Alberto, Rowan, Kathryn M., Saccona, Fabio, Safdarian, Mehdi, Santos, Maria Clariza M., Sasadeusz, Joe, Scozzari, Gitana, Shankar-Hari, Manu, Sharma, Gorav, Snelling, Thomas, Soto, Alonso, Tagayuna, Pedrito Y., Tang, Amy, Tatem, Geneva, Teofili, Luciana, Tong, Steven Y.C., Turgeon, Alexis F., Veloso, Januario D., Venkatesh, Balasubramanian, Ventura-Enriquez, Yanet, Webb, Steve A., Wiese, Lothar, Wikén, Christian, Wood, Erica M., Yusubalieva, Gaukhar M., Zacharowski, Kai, Zarychanski, Ryan, Khanna, Nina, Moher, David, Goodman, Steven N., Ioannidis, John P.A., and Hemkens, Lars G.

Abstract

Background: Convalescent plasma has been widely used to treat COVID-19 and is under investigation in numerous randomized clinical trials, but results are publicly available only for a small number of trials. The objective of this study was to assess the benefits of convalescent plasma treatment compared to placebo or no treatment and all-cause mortality in patients with COVID-19, using data from all available randomized clinical trials, including unpublished and ongoing trials (Open Science Framework, https://doi.org/10.17605/OSF.IO/GEHFX). Methods: In this collaborative systematic review and meta-analysis, clinical trial registries (ClinicalTrials.gov, WHO International Clinical Trials Registry Platform), the Cochrane COVID-19 register, the LOVE database, and PubMed were searched until April 8, 2021. Investigators of trials registered by March 1, 2021, without published results were contacted via email. Eligible were ongoing, discontinued and completed randomized clinical trials that compared convalescent plasma with placebo or no treatment in COVID-19 patients, regardless of setting or treatment schedule. Aggregated mortality data were extracted from publications or provided by investigators of unpublished trials and combined using the Hartung–Knapp–Sidik–Jonkman random effects model. We investigated the contribution of unpublished trials to the overall evidence. Results: A total of 16,477 patients were included in 33 trials (20 unpublished with 3190 patients, 13 published with 13,287 patients). 32 trials enrolled only hospitalized patients (including 3 with only intensive care unit patients). Risk of bias was low for 29/33 trials. Of 8495 patients who received convalescent plasma, 1997 died (23%), and of 7982 control patients, 1952 died (24%). The combined risk ratio for all-cause mortality was 0.97 (95% confidence interval: 0.92; 1.02) with between-study heterogeneity not beyond chance (I2 = 0%). The RECOVERY trial had 69.8% and the unpublished evi

Published
2021

37. Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members.

Author

Reichert, Martin, Sartelli, Massimo, Weigand, Markus A., Hecker, Matthias, Oppelt, Philip U., Noll, Julia, Askevold, Ingolf H., Liese, Juliane, Padberg, Winfried, Coccolini, Federico, Catena, Fausto, Hecker, Andreas, The WSES COVID-19 emergency surgery survey collaboration group, Peckham-Cooper, Adam, Camacho-Ortiz, Adrian, Mastoraki, Aikaterini T., Landaluce-Olavarria, Aitor, Pal, Ajay Kumar, Kuriyama, Akira, and Chichom-Mefire, Alain

Subjects
HOSPITAL emergency services, OPERATIVE surgery, CROSS-sectional method, APPENDICITIS, PATIENTS, CHOLECYSTITIS, SURVEYS, TREATMENT effectiveness, TREATMENT delay (Medicine), EMERGENCY medical services, EMPLOYEES' workload, DESCRIPTIVE statistics, INTERNATIONAL agencies, WORKING hours, COVID-19 pandemic, DIVERTICULITIS
Abstract

Background: The SARS-CoV-2 pandemic is still ongoing and a major challenge for health care services worldwide. In the first WSES COVID-19 emergency surgery survey, a strong negative impact on emergency surgery (ES) had been described already early in the pandemic situation. However, the knowledge is limited about current effects of the pandemic on patient flow through emergency rooms, daily routine and decision making in ES as well as their changes over time during the last two pandemic years. This second WSES COVID-19 emergency surgery survey investigates the impact of the SARS-CoV-2 pandemic on ES during the course of the pandemic. Methods: A web survey had been distributed to medical specialists in ES during a four-week period from January 2022, investigating the impact of the pandemic on patients and septic diseases both requiring ES, structural problems due to the pandemic and time-to-intervention in ES routine. Results: 367 collaborators from 59 countries responded to the survey. The majority indicated that the pandemic still significantly impacts on treatment and outcome of surgical emergency patients (83.1% and 78.5%, respectively). As reasons, the collaborators reported decreased case load in ES (44.7%), but patients presenting with more prolonged and severe diseases, especially concerning perforated appendicitis (62.1%) and diverticulitis (57.5%). Otherwise, approximately 50% of the participants still observe a delay in time-to-intervention in ES compared with the situation before the pandemic. Relevant causes leading to enlarged time-to-intervention in ES during the pandemic are persistent problems with in-hospital logistics, lacks in medical staff as well as operating room and intensive care capacities during the pandemic. This leads not only to the need for triage or transferring of ES patients to other hospitals, reported by 64.0% and 48.8% of the collaborators, respectively, but also to paradigm shifts in treatment modalities to non-operative approaches reported by 67.3% of the participants, especially in uncomplicated appendicitis, cholecystitis and multiple-recurrent diverticulitis. Conclusions: The SARS-CoV-2 pandemic still significantly impacts on care and outcome of patients in ES. Well-known problems with in-hospital logistics are not sufficiently resolved by now; however, medical staff shortages and reduced capacities have been dramatically aggravated over last two pandemic years. [ABSTRACT FROM AUTHOR]

Published
2022
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48. Impact of the SARS-CoV-2 pandemic on emergency surgery services—a multi-national survey among WSES members.

Author

Reichert, Martin, Sartelli, Massimo, Weigand, Markus A., Doppstadt, Christoph, Hecker, Matthias, Reinisch-Liese, Alexander, Bender, Fabienne, Askevold, Ingolf, Padberg, Winfried, Coccolini, Federico, Catena, Fausto, Hecker, Andreas, The WSES COVID-19 emergency surgery survey collaboration group, Abdullaev, Abakar, Camacho-Ortiz, Adrian, Toro, Adriana, Chichom-Mefire, Alain, Martínez-Pérez, Aleix, Kavalakat, Alfie J., and Mohamedahmed, Ali Yasen Y.

Subjects
SURGERY & psychology, APPENDICITIS, CHOLECYSTITIS, HOSPITAL emergency services, MEDICAL care, MEDICAL needs assessment, PATIENTS, SEPSIS, SURGEONS, OPERATIVE surgery, MEDICAL triage, WORLD Wide Web, SEVERITY of illness index, DESCRIPTIVE statistics, TREATMENT delay (Medicine), COVID-19 pandemic
Abstract

Background: The SARS-CoV-2 pandemic is a major challenge for health care services worldwide. It's impact on oncologic therapies and elective surgery has been described recently, and the literature provides guidelines regarding appropriate elective patient treatment during the pandemic. However, the impact of SARS-CoV-2 pandemic on emergency surgery services has been poorly investigated up to now. Methods: A 17-item web survey had been distributed to emergency surgeons in June 2020 around the world, investigating the impact of SARS-CoV-2 pandemic on patients and septic diseases both requiring emergency surgery and the time-to-intervention in emergency surgery routine, as well as experiences with surgery in COVID-19 patients. Results: Ninety-eight collaborators from 31 countries responded to the survey. The majority (65.3%) estimated the impact of the SARS-CoV-2 pandemic on emergency surgical patient care as being strong or very strong. Due to the pandemic, 87.8% reported a decrease in the total number of patients undergoing emergency surgery and approximately 25% estimated a delay of more than 2 h in the time-to-diagnosis and another 2 h in the time-to-intervention. Fifty percent make structural problems with in-hospital logistics (e.g. transport of patients, closed normal wards etc.) mainly responsible for delayed emergency surgery and the frequent need (56.1%) for a triage of emergency surgical patients. 56.1% of the collaborators observed more severe septic abdominal diseases during the pandemic, especially for perforated appendicitis and severe septic cholecystitis (41.8% and 40.2%, respectively). 62.2% had experiences with surgery in COVID-19-infected patients. Conclusions: The results of The WSES COVID-19 emergency surgery survey are alarming. The combination of an estimated decrease in numbers of emergency surgical patients and an observed increase in more severe septic diseases may be a result of the fear of patients from infection with COVID-19 and a consecutive delayed hospital admission and diagnosis. A critical delay in time-to-diagnosis and time-to-intervention may be a result of changes in in-hospital logistics and operating room as well as intensive care capacities. Both reflect the potentially harmful impact of SARS-CoV-2 pandemic on emergency surgery services. [ABSTRACT FROM AUTHOR]

Published
2020
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49. Additional file 1: of The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardshipâ results from an international cross-sectional survey

Author

Sartelli, Massimo, Labricciosa, Francesco, Barbadoro, Pamela, Pagani, Leonardo, Ansaloni, Luca, Brink, Adrian, Carlet, Jean, Khanna, Ashish, Chichom-Mefire, Alain, Coccolini, Federico, Salomone Di Saverio, May, Addison, Viale, Pierluigi, Watkins, Richard, Scudeller, Luigia, Abbo, Lilian, Abu-Zidan, Fikri, Abdulrashid Adesunkanmi, Al-Dahir, Sara, Al-Hasan, Majdi, Alis, Halil, Alves, Carlos, André Araujo Da Silva, Augustin, Goran, Miklosh Bala, Barie, Philip, Beltrán, Marcelo, Bhangu, Aneel, Belefquih Bouchra, Brecher, Stephen, CaíNzos, Miguel, Camacho-Ortiz, Adrian, Catani, Marco, Sujith Chandy, Asri Jusoh, Cherry-Bukowiec, Jill, Chiara, Osvaldo, Colak, Elif, Cornely, Oliver, Yunfeng Cui, Demetrashvili, Zaza, Simone, Belinda De, Waele, Jan De, Dhingra, Sameer, Marzo, Francesco Di, Dogjani, Agron, Gereltuya Dorj, Dortet, Laurent, Duane, Therese, Elmangory, Mutasim, Mushira Enani, Ferrada, Paula, J. Esteban Foianini, Gachabayov, Mahir, Chinmay Gandhi, Wagih Ghnnam, Giamarellou, Helen, Gkiokas, Georgios, Gomi, Harumi, Goranovic, Tatjana, Griffiths, Ewen, Rosio Guerra Gronerth, Monteiro, Julio Haidamus, Hardcastle, Timothy, Hecker, Andreas, Hodonou, Adrien, Orestis Ioannidis, Isik, Arda, Iskandar, Katia, Kafil, Hossein, Kanj, Souha, Kaplan, Lewis, Kapoor, Garima, Karamarkovic, Aleksandar, Kenig, Jakub, Kerschaever, Ivan, Faryal Khamis, Khokha, Vladimir, Kiguba, Ronald, Kim, Hong, Wen-Chien Ko, Koike, Kaoru, Kozlovska, Iryna, Kumar, Anand, Lagunes, Leonel, Latifi, Rifat, Lee, Jae, Lee, Young, LeppäNiemi, Ari, Yousheng Li, Liang, Stephen, Lowman, Warren, Machain, Gustavo, Maegele, Marc, Major, Piotr, Malama, Sydney, Manzano-Nunez, Ramiro, Marinis, Athanasios, Casas, Isidro Martinez, Marwah, Sanjay, Maseda, Emilio, McFarlane, Michael, Memish, Ziad, Mertz, Dominik, Mesina, Cristian, Mishra, Shyam, Moore, Ernest, Akutu Munyika, Mylonakis, Eleftherios, Napolitano, Lena, Negoi, Ionut, Nestorovic, Milica, Nicolau, David, Abdelkarim Omari, Ordonez, Carlos, José-Artur Paiva, Pant, Narayan, Parreira, Jose, PęDziwiatr, Michal, Pereira, Bruno, Ponce-De-Leon, Alfredo, Garyphallia Poulakou, Preller, Jacobus, Céline Pulcini, Pupelis, Guntars, Quiodettis, Martha, Rawson, Timothy, Reis, Tarcisio, Rems, Miran, Rizoli, Sandro, Roberts, Jason, Pereira, Nuno, Jesús RodríGuez-Baño, Sakakushev, Boris, Sanders, James, Santos, Natalia, Sato, Norio, Sawyer, Robert, Scarpelini, Sandro, Scoccia, Loredana, Shafiq, Nusrat, Vishalkumar Shelat, Costi Sifri, Boonying Siribumrungwong, SøReide, Kjetil, Soto, Rodolfo, Souza, Hamilton De, Talving, Peep, Ngo Trung, Tessier, Jeffrey, Tumbarello, Mario, Ulrych, Jan, Uranues, Selman, Goor, Harry Van, Andras Vereczkei, Wagenlehner, Florian, Yonghong Xiao, Kuo-Ching Yuan, Wechsler-Fördös, Agnes, Jean-Ralph Zahar, Zakrison, Tanya, Zuckerbraun, Brian, Zuidema, Wietse, and Catena, Fausto

Abstract

The international cross-sectional survey. (DOC 56 kb)

Published
2017
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