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15 results on '"Camba, Lionello"'

5. Cardiovascular Risk: Analysis of Known Factors in Patients After Treosulfan-Based Conditioning for Haploidentical and HLA-Identical Stem Cell Transplantation

Author

Forcina, Alessandra, primary, Lupo Stanghellini, Maria Teresa, additional, Greco, Raffaella, additional, Lorusso, Alessandro, additional, Clerici, Daniela, additional, Peccatori, Jacopo, additional, Bernardi, Massimo, additional, Lunghi, Francesca, additional, Marcatti, Magda, additional, Camba, Lionello, additional, Guggiari, Elena, additional, Assanelli, Andrea, additional, Bondanza, Attilio, additional, Carrabba, Matteo, additional, Marktel, Sarah, additional, Corti, Consuelo, additional, and Ciceri, Fabio, additional

Published
2011
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6. Effect of Related and Unrelated Donor Haemopoietic Stem-Cell Transplantation on Outcome In Adults with High Risk Acute Leukemia: An Intention-to-Treat Analysis at a Single Center Institution

Author

Lupo-Stanghellini, Maria Teresa, primary, Marcatti, Magda, additional, Coppola, Milena, additional, Forno, Barbara, additional, Bitetti, Cinzia, additional, Sala, Elisa, additional, Assanelli, Andrea, additional, Greco, Raffaella, additional, Lunghi, Francesca, additional, Crotta, Alessandro, additional, Tassara, Michela, additional, Calbi, Valeria, additional, Matteazzi, Francesca, additional, Guggiari, Elena, additional, Carrabba, Matteo, additional, Camba, Lionello, additional, Clerici, Daniela, additional, Malato, Simona, additional, Marktel, Sarah, additional, Fleischhauer, Katharina, additional, Bonini, Chiara, additional, Bordignon, Claudio, additional, Corti, Consuelo, additional, Bernardi, Massimo, additional, Peccatori, Jacopo, additional, and Ciceri, Fabio, additional

Published
2010
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7. Implementation of An Alternative Donor Option Is Prerequisite for a Good Intention-to-Treat (ITT) In Patients In Need of Allogeneic Transplantation: Analysis of 410 Patients

Author

Lupo-Stanghellini, Maria Teresa, primary, Forno, Barbara, additional, Marcatti, Magda, additional, Bitetti, Cinzia, additional, Coppola, Milena, additional, Assanelli, Andrea, additional, Greco, Raffaella, additional, Lunghi, Francesca, additional, Tassara, Michela, additional, Guggiari, Elena, additional, Carrabba, Matteo, additional, Matteazzi, Francesca, additional, Camba, Lionello, additional, Clerici, Daniela, additional, Malato, Simona, additional, Marktel, Sarah, additional, Bonini, Chiara, additional, Bordignon, Claudio, additional, Corti, Consuelo, additional, Bernardi, Massimo, additional, Peccatori, Jacopo, additional, and Ciceri, Fabio, additional

Published
2010
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8. Combined Treatment with High-Dose Methotrexate, Vincristine and Procarbazine, without Intrathecal Chemotherapy, Followed by Consolidation Radiotherapy for Primary Central Nervous System Lymphoma in Immunocompetent Patients

Author

Ferreri, Andrés J.M., primary, Reni, Michele, additional, Dell’Oro, Stefania, additional, Ciceri, Fabio, additional, Bernardi, Massimo, additional, Camba, Lionello, additional, Ponzoni, Maurilio, additional, Terreni, Maria Rosa, additional, Tomirotti, Maurizio, additional, Spina, Michele, additional, and Villa, Eugenio, additional

Published
2001
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11. Functions of T cells and recruitment of cellular response after in vitro mitogenic stimulation of lymphocytes in chronic lymphocytic leukaemia.

Author

Neri, Alberto, Paciucci, Paolo, Brugiatelli, Maura, Camba, Lionello, Comis, Margherita, Iacopino, Pasquale, Nobile, Francesco, and Lombardo, Vincenzo

Abstract

In vitro stimulation of peripheral blood lymphocytes from ten patients with chronic lymphocytic leukaemia (CLL) was investigated under various culture conditions. It was confirmed that the mitogenic reactivity of whole cell populations (PBL) was delayed and depressed. When CLL rosette-forming cells (RFC) were stimulated, theirH-thymidine uptake was increased, but the pattern of the response was similar to that of whole PBL, thus suggesting some impairment of these cells. Furthermore, in order to evaluate the possible recruitment of B cells, generally thought to be unresponsive, some co-culture experiments were performed in which 10 normal lymphocytes and 10 CLL whole PBL or RFC-depleted cell populations were stimulated with mitogens. An amplified response of the CLL lymphocytes was obtained in all co-cultures, and this effect was more evident when specific T cell stimulants were used; autologous CLL T lymphocytes, on the contrary, failed to display such a 'synergic' effect. These results indicate that normal lymphocytes are able to recruit a large number of CLL lymphocytes in the mitogenic response; furthermore, the fact that in co-cultures of CLL T-depleted fractions a better response was obtained with T cell mitogens suggests that the definition of CLL as a clonal expansion of unresponsive 'B' lymphocytes may be inadequate. [ABSTRACT FROM AUTHOR]

Published
1979
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12. Functions of T cells and recruitment of cellular response afterin vitromitogenic stimulation of lymphocytes in chronic lymphocytic leukaemia

Author

Neri, Alberto, Paciucci, Paolo Alberto, Brugiatelli, Maura, Camba, Lionello, Comis, Margherita, Iacopino, Pasquale, Nobile, Francesco, and Lombardo, Vincenzo Trapani

Abstract

In vitrostimulation of peripheral blood lymphocytes from ten patients with chronic lymphocytic leukaemia (CLL) was investigated under various culture conditions. It was confirmed that the mitogenic reactivity of whole cell populations (PBL) was delayed and depressed. When CLL rosette-forming cells (RFC) were stimulated, their3H-thymidine uptake was increased, but the pattern of the response was similar to that of whole PBL, thus suggesting some impairment of these cells. Furthermore, in order to evaluate the possible recruitment of B cells, generally thought to be unresponsive, some co-culture experiments were performed in which 104normal lymphocytes and 105CLL whole PBL or RFC-depleted cell populations were stimulated with mitogens. An amplified response of the CLL lymphocytes was obtained in all co-cultures, and this effect was more evident when specific T cell stimulants were used; autologous CLL T lymphocytes, on the contrary, failed to display such a ‘synergic’ effect. These results indicate that normal lymphocytes are able to recruit a large number of CLL lymphocytes in the mitogenic response; furthermore, the fact that in co-cultures of CLL T-depleted fractions a better response was obtained with T cell mitogens suggests that the definition of CLL as a clonal expansion of unresponsive ‘B’ lymphocytes may be inadequate.

Published
1979
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13. In vitroproliferative response of chronic lymphocytic leukemia

Author

Neri, Alberto, Paciucci, Paolo Alberto, Nobile, Francesco, Brugiatelli, Maura, Camba, Lionello, Comis, Margherita, Iacopino, Pasquale, and Lombardo, Vincenzo Trapani

Abstract

The peripheral blood lymphocytes of 13 previously untreated chronic lymphocytic leukemia (CLL) patients showed a decreased and delayed responsein vitroto plant mitogens (PHA and PWM) and specific antigens (PPD and MLC). In addition, the serum of these patients inhibited the mitotic reactivity of both autologous and homologous normal lymphocytes. Since incubation with CLL serum did not affect the SRBC-rosetting capacity of normal lymphocytes, we believe that CLL serum interferes with some metabolic stage in blastogenesis rather than at the level of mitogen membrane interaction. Thein vitrotransformation of lymph node, bone marrow and peripheral blood lymphocytes in some of these patients was also investigated. Stimulation of peripheral blood cells with plant mitogens resulted in a more serious impairment of the response than that found with bone marrow and lymph node cells. This could be explained by the fact that, although CLL is a widespread lymphoproliferative disorder, some preferential homing of normally reactive cells in the bone marrow and lymph nodes cannot be excluded. Finally, since no stimulation was observed in mixed leukocyte cultures (MLC), our experiments provide evidence that no antigenic differences are detectable in CLL lymphoid populations.

Published
1977
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