432,936 results on '"Cameron, A"'
Search Results
2. Science Fiction's Facial Optics
- Author
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Cameron, Allan
- Published
- 2024
- Full Text
- View/download PDF
3. Unbuttoning America
- Author
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Cameron, Ardis
- Subjects
publishing industry, Grace Metalious, incest novels, sex and gender, 1950s US, women's history, sexuality, abortion ,Literature: history and criticism ,History of the Americas ,Biography: writers - Abstract
Published in 1956, Peyton Place became a bestseller and a literary phenomenon. A lurid and gripping story of murder, incest, female desire, and social injustice, it was consumed as avidly by readers as it was condemned by critics and the clergy. Its author, Grace Metalious, a housewife who grew up in poverty in a New Hampshire mill town and had aspired to be a writer from childhood, loosely based the novel’s setting, characters, and incidents on real-life places, people, and events. The novel sold more than 30 million copies in hardcover and paperback, and it was adapted into a hit Hollywood film in 1957 and a popular television series that aired from 1964 to 1969. More than half a century later, the term ""Peyton Place"" is still in circulation as a code for a community harboring sordid secrets. In Unbuttoning America, Ardis Cameron mines extensive interviews, fan letters, and archival materials including contemporary cartoons and cover images from film posters and foreign editions to tell how the story of a patricide in a small New England village circulated over time and became a cultural phenomenon. She argues that Peyton Place, with its frank discussions of poverty, sexuality, class and ethnic discrimination, and small-town hypocrisy, was more than a tawdry potboiler. Metalious’s depiction of how her three central female characters come to terms with their identity as women and sexual beings anticipated second-wave feminism. More broadly, Cameron asserts, the novel was also part of a larger postwar struggle over belonging and recognition. Fictionalizing contemporary realities, Metalious pushed to the surface the hidden talk and secret rebellions of a generation no longer willing to ignore the disparities and domestic constraints of Cold War America. ; Published in 1956, Peyton Place became a bestseller and a literary phenomenon. A lurid and gripping story of murder, incest, female desire, and social injustice, it was consumed as avidly by readers as it was condemned by critics and the clergy. Its author, Grace Metalious, a housewife who grew up in poverty in a New Hampshire mill town and had aspired to be a writer from childhood, loosely based the novel's setting, characters, and incidents on real-life places, people, and events. The novel sold more than 30 million copies in hardcover and paperback, and it was adapted into a hit Hollywood film in 1957 and a popular television series that aired from 1964 to 1969. More than half a century later, the term "Peyton Place" is still in circulation as a code for a community harboring sordid secrets.In Unbuttoning America, Ardis Cameron mines extensive interviews, fan letters, and archival materials including contemporary cartoons and cover images from film posters and foreign editions to tell how the story of a patricide in a small New England village circulated over time and became a cultural phenomenon. She argues that Peyton Place, with its frank discussions of poverty, sexuality, class and ethnic discrimination, and small-town hypocrisy, was more than a tawdry potboiler. Metalious's depiction of how her three central female characters come to terms with their identity as women and sexual beings anticipated second-wave feminism. More broadly, Cameron asserts, the novel was also part of a larger postwar struggle over belonging and recognition. Fictionalizing contemporary realities, Metalious pushed to the surface the hidden talk and secret rebellions of a generation no longer willing to ignore the disparities and domestic constraints of Cold War America.
- Published
- 2024
4. Work Engendered: Toward a New History of American Labor ed. by Ava Baron (review)
- Author
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Cameron, Ardis
- Published
- 2023
5. Aspirations and Anxieties: New England Workers and the Mechanized Factory System, 1815–1850 by David A. Zonderman (review)
- Author
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Cameron, Ardis
- Published
- 2023
6. Donor Support to Inclusive Education for Children with Disabilities: Who Does What in GPE Partner Countries?
- Author
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Global Partnership for Education (GPE), Stuart Cameron, Sophia D’Angelo, Daniela Gamboa Zapatel, and Maria Qureshi
- Abstract
Children with disabilities remain among the most excluded from education in Global Partnership for Education (GPE) partner countries and other lower-income countries. Despite considerable activity funded both through GPE and by other donors, as well as by partner countries themselves, the level of international support to inclusive education remains too low and patchy for countries to transform their education systems so they are fully inclusive of children with disabilities. Development partners need to coordinate; help to build a stronger evidence base at global, regional and national levels; and go beyond isolated interventions to support reforms that have the potential to make the whole system more inclusive. To do this, development partners need to share knowledge on their activities globally and at the country level. This paper, and the underlying mapping exercise, aims to facilitate knowledge sharing in the sector by analyzing thematic and geographic focus areas of major development partners supporting inclusive education.
- Published
- 2024
7. Who Says 'Ps Get Degrees'? Examining the Profile of Undergraduate Students Maintaining High Achievement at University
- Author
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Cameron Lydster
- Abstract
The circumstances associated with high levels of achievement in undergraduate studies has not been thoroughly explored in the Australian context. This study investigated factors predicting high academic achievement, defined as maintaining a Distinction average, at undergraduate level. Findings revealed several factors that predicted achievement after two semesters of study. These factors included essay writing skills, with students having satisfactory writing 5.16 times more likely to maintain a Distinction average compared to those with below satisfactory writing; faculty, with students enrolled in Health Sciences 4.63 times more likely compared to students from other faculties; language background, with English-speaking background students 1.67 times more likely compared to English as an additional language or dialect (EAL/D) students; gender, with females 1.45 more likely compared to males; and age, with older students 1.03 times more likely to achieve high performance compared to younger students. Creating a profile of students likely to excel academically assists decision makers in allocating resources to students less likely to achieve. This research opens the door to further studies investigating whether these factors play a role in predicting student achievement at university.
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- 2024
8. Chapter 10 Telepractice in adult speech-language pathology during COVID-19
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Ward, Elizabeth C. and Cameron, Ashley E.
- Subjects
communication ,COVID-19 ,dysphagia ,healthcare ,service delivery ,speech-language pathology ,telehealth ,telepractice ,Language: reference and general ,Linguistics - Abstract
This collection is the first of its kind to examine the impact of the COVID-19 pandemic on the caseloads and clinical practice of speech-language pathologists. The volume synthesises existing data on the wide-ranging effects of COVID-19 on the communication, swallowing, and language skills of individuals with COVID infection. Featuring perspectives of scholars and practitioners from around the globe, the book examines the ways in which clinicians have had to modify their working practices to prioritise patient and clinician safety, including the significant increase in the use of telepractice during the pandemic. The volume also reflects on changes in training and education which have seen educators in the field redesign their clinical practicum in order to best prepare students for professional practice in an age of COVID-19 and beyond, as the field continues to grapple with the long-term effects of the pandemic. Offering a holistic treatment of the impact of COVID-19 on the work of speech-language pathologists, this book will be of interest to students, researchers, and clinicians working in the discipline.
- Published
- 2022
- Full Text
- View/download PDF
9. Equilibrium stresses in frameworks via symmetric averaging
- Author
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Millar, Cameron, Schulze, Bernd, and Theran, Louis
- Subjects
Mathematics - Metric Geometry ,52C25, 74K25, 20C35 - Abstract
For a bar-joint framework $(G,p)$, a subgroup $\Gamma$ of the automorphism group of $G$, and a subgroup of the orthogonal group isomorphic to $\Gamma$, we introduce a symmetric averaging map which produces a bar-joint framework on $G$ with that symmetry. If the original configuration is ``almost symmetric", then the averaged one will be near the original configuration. With a view on structural engineering applications, we then introduce a hierarchy of definitions of ``localised" and ``non-localised" or ``extensive" self-stresses of frameworks and investigate their behaviour under the symmetric averaging procedure. Finally, we present algorithms for finding non-degenerate symmetric frameworks with many states of self-stress, as well as non-symmetric and symmetric frameworks with extensive self-stresses. The latter uses the symmetric averaging map in combination with symmetric Maxwell-type character counts and a procedure based on the pure condition from algebraic geometry. These algorithms provide new theoretical and computational tools for the design of engineering structures such as gridshell roofs., Comment: 29 pages, 12 figures
- Published
- 2025
10. Stabilization of magnetic bubbles in [Ni/Co]$_{n}$ multilayers on an oxygen-reconstructed Nb(110) surface via an ultra-thin Cu interlayer
- Author
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Dibajeh, Ahmad, Johnson, Cameron W., Schmid, Andreas K., and Conte, Roberto Lo
- Subjects
Condensed Matter - Materials Science ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Magnetic thin films hosting topological spin textures, such as magnetic skyrmions, hold high potential for breakthroughs in the field of spintronics, due to good scalability and energy efficiency. Novel computational architectures such as memory-in-logic devices rely on material platforms able to host those topological spin textures. Furthermore, recently proposed designs of novel quantum information technologies are based on heterostructures where topological spin textures are in direct proximity to a superconducting layer. Here, we demonstrate the stabilization of out-of-plane magnetic bubbles in highly ordered [Ni/Co]$_{n}$ multilayers on a Nb(110) single crystal. This is achieved without the need for removal of the well-known Nb(110)-oxide surface reconstruction, due to the introduction of a one-atom-thick Cu interlayer in between the Nb substrate and the magnetic multilayer. The Cu interlayer generates a well-ordered hexagonal surface, which is key for the epitaxial growth of the [Ni/Co]$_{n}$ multilayers hosting the desired out-of-plane anisotropy. The magnetic ground state of the prepared material stacks is directly imaged via spin-polarized low energy electron microscopy (SPLEEM), revealing the presence of magnetic bubble domains with lateral sizes as small as 450 nm.
- Published
- 2025
11. A Renewable Double Plasma Mirror For Petawatt-class Lasers
- Author
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Czapla, Nick, Nasir, Derek M., Obst-Huebl, Lieselotte, Zingale, Anthony, Bin, Jianhui, Gonsalves, Anthony J., Steinke, Sven, Nakamura, Kei, Schroeder, Carl B., Esarey, Eric, Geddes, Cameron G. R., and Schumacher, Douglass
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Physics - Plasma Physics ,Physics - Optics - Abstract
Exceptional pulse contrast can be critical for ultraintense laser experiments, particularly when using solid density targets, and their use is becoming widespread. However, current plasma mirror technology is becoming inadequate for the new generation of high repetition rate, high power lasers now available. We describe a novel double plasma mirror configuration based on renewable, free standing, ultrathin liquid crystal films tested at the BELLA Petawatt Laser Center. Although operating at a repetition rate of several shots per minute, this system can be scaled to a high repetition rate exceeding 1 Hz and represents an important step towards enabling sustained, continuous operation of plasma mirrors. We demonstrate an improvement of two to three orders of magnitude in contrast and a total throughput of 80%. We present the first measurements of a beam reflected from a single or double plasma mirror system using a wavefront sensor, showing a well preserved wavefront and spatial mode. Finally, we introduce a model that predicts the total throughput through this double plasma mirror. This is the first model that accurately predicts the peak reflectivity of a plasma mirror when given the laser temporal profile., Comment: 11 pages, 6 figures, 7 equations
- Published
- 2025
12. AR Glulam: Accurate Augmented Reality Using Multiple Fiducial Markers for Glulam Fabrication
- Author
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Kyaw, Alexander Htet, Xu, Arvin, Zivkovic, Sasa, Jahn, Gwyllim, Newnham, Cameron, and Berg, Nick Van Den
- Subjects
Computer Science - Emerging Technologies ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Human-Computer Interaction - Abstract
Recent advancements in Augmented Reality (AR) have demonstrated applications in architecture, design, and fabrication. Compared to conventional 2D construction drawings, AR can be used to superimpose contextual instructions, display 3D spatial information and enable on-site engagement. Despite the potential of AR, the widespread adoption of the technology in the industry is limited by its precision. Precision is important for projects requiring strict construction tolerances, design fidelity, and fabrication feedback. For example, the manufacturing of glulam beams requires tolerances of less than 2mm. The goal of this project is to explore the industrial application of using multiple fiducial markers for high-precision AR fabrication. While the method has been validated in lab settings with a precision of 0.97, this paper focuses on fabricating glulam beams in a factory setting with an industry manufacturer, Unalam Factory., Comment: 10 Figures, Project Paper for Association for Computer Aided Design in Architecture
- Published
- 2025
13. LucidAtlas$: Learning Uncertainty-Aware, Covariate-Disentangled, Individualized Atlas Representations
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Jiao, Yining, Bhamidi, Sreekalyani, Qu, Huaizhi, Zdanski, Carlton, Kimbell, Julia, Prince, Andrew, Worden, Cameron, Kirse, Samuel, Rutter, Christopher, Shields, Benjamin, Dunn, William, Mahmud, Jisan, Chen, Tianlong, and Niethammer, Marc
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Computer Science - Machine Learning - Abstract
The goal of this work is to develop principled techniques to extract information from high dimensional data sets with complex dependencies in areas such as medicine that can provide insight into individual as well as population level variation. We develop $\texttt{LucidAtlas}$, an approach that can represent spatially varying information, and can capture the influence of covariates as well as population uncertainty. As a versatile atlas representation, $\texttt{LucidAtlas}$ offers robust capabilities for covariate interpretation, individualized prediction, population trend analysis, and uncertainty estimation, with the flexibility to incorporate prior knowledge. Additionally, we discuss the trustworthiness and potential risks of neural additive models for analyzing dependent covariates and then introduce a marginalization approach to explain the dependence of an individual predictor on the models' response (the atlas). To validate our method, we demonstrate its generalizability on two medical datasets. Our findings underscore the critical role of by-construction interpretable models in advancing scientific discovery. Our code will be publicly available upon acceptance., Comment: 28 pages
- Published
- 2025
14. In-depth characterization of the Kepler-10 three-planet system with HARPS-N RVs and Kepler TTVs
- Author
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Bonomo, A. S., Borsato, L., Rajpaul, V. M., Zeng, L., Damasso, M., Hara, N. C., Cretignier, M., Leleu, A., Unger, N., Dumusque, X., Lienhard, F., Mortier, A., Naponiello, L., Malavolta, L., Sozzetti, A., Latham, D. W., Rice, K., Bongiolatti, R., Buchhave, L., Cameron, A. C., Fiorenzano, A. F., Ghedina, A., Haywood, R. D., Lacedelli, G., Massa, A., Pepe, F., Poretti, E., and Udry, S.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The old G3V star Kepler-10 is known to host two transiting planets, the ultra-short-period super-Earth Kepler-10b ($P=0.837$ d; $R_{\rm p}=1.47~\rm R_\oplus$) and the long-period sub-Neptune Kepler-10c ($P=45.294$ d; $R_{\rm p}=2.35~\rm R_\oplus$), and a non-transiting planet causing variations in the Kepler-10c transit times. Measurements of the mass of Kepler-10c in the literature have shown disagreement, depending on the radial-velocity dataset and/or the modeling technique used. Here we report on the analysis of almost 300 high-precision radial velocities gathered with the HARPS-N spectrograph at the Telescopio Nazionale Galileo over $\sim11$~years, and extracted with the YARARA-v2 tool correcting for possible systematics and/or low-level activity variations at the spectrum level. To model these radial velocities, we used three different noise models and various numerical techniques, which all converged to the solution: $M_{\rm p, b}=3.24 \pm 0.32~\rm M_\oplus$ (10$\sigma$) and $\rho_{\rm p, b}=5.54 \pm 0.64~\rm g\;cm^{-3}$ for planet b; $M_{\rm p, c}=11.29 \pm 1.24~\rm M_\oplus$ (9$\sigma$) and $\rho_{\rm p, c}=4.75 \pm 0.53~\rm g\;cm^{-3}$ for planet c; and $M_{\rm p, d}\sin{i}=12.00 \pm 2.15~\rm M_\oplus$ (6$\sigma$) and $P=151.06 \pm 0.48$ d for the non-transiting planet Kepler-10d. This solution is further supported by the analysis of the Kepler-10c transit timing variations and their simultaneous modeling with the HARPS-N radial velocities. While Kepler-10b is consistent with a rocky composition and a small or no iron core, Kepler-10c may be a water world that formed beyond the water snowline and subsequently migrated inward., Comment: 15 pages, 12 figures, 5 tables, accepted for publication in Astronomy and Astrophysics
- Published
- 2025
15. Searching for Hot Water World Candidates with CHEOPS: Refining the radii and analysing the internal structures and atmospheric lifetimes of TOI-238 b and TOI-1685 b
- Author
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Egger, J. A., Kubyshkina, D., Alibert, Y., Osborn, H. P., Bonfanti, A., Wilson, T. G., Brandeker, A., Günther, M. N., Lendl, M., Kitzmann, D., Fossati, L., Mordasini, C., Sousa, S. G., Adibekyan, V., Fridlund, M., Pezzotti, C., Gandolfi, D., Ulmer-Moll, S., Alonso, R., Bárczy, T., Navascues, D. Barrado, Barros, S. C., Baumjohann, W., Benz, W., Billot, N., Borsato, L., Broeg, C., Cameron, A. Collier, Correia, A. C. M., Csizmadia, Sz., Cubillos, P. E., Davies, M. B., Deleuil, M., Deline, A., Demangeon, O. D. S., Demory, B. -O., Derekas, A., Edwards, B., Ehrenreich, D., Erikson, A., Fortier, A., Gazeas, K., Gillon, M., Güdel, M., Heitzmann, A., Helling, Ch., Isaak, K. G., Kiss, L., Korth, J., Lam, K. W. F., Laskar, J., Etangs, A. Lecavelier des, Luntzer, A., Luque, R., Magrin, D., Maxted, P. F. L., Merín, B., Munari, M., Nascimbeni, V., Olofsson, G., Ottensamer, R., Pagano, I., Pallé, E., Peter, G., Piazza, D., Piotto, G., Pollacco, D., Queloz, D., Ragazzoni, R., Rando, N., Rauer, H., Ribas, I., Santos, N. C., Scandariato, G., Ségransan, D., Simon, A. E., Smith, A. M. S., Southworth, R., Stalport, M., Sulis, S., Szabó, M. Gy., Udry, S., Van Grootel, V., Venturini, J., Villaver, E., Walton, N. A., Wolf, S., and Wolter, D.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Studying the composition of exoplanets is one of the most promising approaches to observationally constrain planet formation and evolution processes. However, this endeavour is complicated for small exoplanets by the fact that a wide range of compositions is compatible with their bulk properties. To overcome this issue, we identify triangular regions in the mass-radius space where part of this degeneracy is lifted for close-in planets, since low-mass H/He envelopes would not be stable due to high-energy stellar irradiation. Planets in these Hot Water World triangles need to contain at least some heavier volatiles and are therefore interesting targets for atmospheric follow-up observations. We perform a demographic study to show that only few well-characterised planets in these regions are currently known and introduce our CHEOPS GTO programme aimed at identifying more of these potential hot water worlds. Here, we present CHEOPS observations for the first two targets of our programme, TOI-238 b and TOI-1685 b. Combined with TESS photometry and published RVs, we use the precise radii and masses of both planets to study their location relative to the corresponding Hot Water World triangles, perform an interior structure analysis and study the lifetimes of H/He and water-dominated atmospheres under these conditions. We find that TOI-238 b lies, at the 1-sigma level, inside the corresponding triangle. While a pure H/He atmosphere would have evaporated after 0.4-1.3 Myr, it is likely that a water-dominated atmosphere would have survived until the current age of the system, which makes TOI-238 b a promising hot water world candidate. Conversely, TOI-1685 b lies below the mass-radius model for a pure silicate planet, meaning that even though a water-dominated atmosphere would be compatible both with our internal structure and evaporation analysis, we cannot rule out the planet to be a bare core., Comment: 25 pages, 16 figures, accepted for publication in A&A
- Published
- 2025
16. Exploring Visual Embedding Spaces Induced by Vision Transformers for Online Auto Parts Marketplaces
- Author
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Armijo, Cameron and Rivas, Pablo
- Subjects
Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Machine Learning ,I.5.3 ,I.2.10 ,I.5.4 - Abstract
This study examines the capabilities of the Vision Transformer (ViT) model in generating visual embeddings for images of auto parts sourced from online marketplaces, such as Craigslist and OfferUp. By focusing exclusively on single-modality data, the analysis evaluates ViT's potential for detecting patterns indicative of illicit activities. The workflow involves extracting high-dimensional embeddings from images, applying dimensionality reduction techniques like Uniform Manifold Approximation and Projection (UMAP) to visualize the embedding space, and using K-Means clustering to categorize similar items. Representative posts nearest to each cluster centroid provide insights into the composition and characteristics of the clusters. While the results highlight the strengths of ViT in isolating visual patterns, challenges such as overlapping clusters and outliers underscore the limitations of single-modal approaches in this domain. This work contributes to understanding the role of Vision Transformers in analyzing online marketplaces and offers a foundation for future advancements in detecting fraudulent or illegal activities., Comment: AAAI 2025 Workshop on AI for Social Impact: Bridging Innovations in Finance, Social Media, and Crime Prevention
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- 2025
17. A Decoding Algorithm for Length-Control Summarization Based on Directed Acyclic Transformers
- Author
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Huang, Chenyang, Zhou, Hao, Jen, Cameron, Zheng, Kangjie, Zaïane, Osmar R., and Mou, Lili
- Subjects
Computer Science - Computation and Language - Abstract
Length-control summarization aims to condense long texts into a short one within a certain length limit. Previous approaches often use autoregressive (AR) models and treat the length requirement as a soft constraint, which may not always be satisfied. In this study, we propose a novel length-control decoding algorithm based on the Directed Acyclic Transformer (DAT). Our approach allows for multiple plausible sequence fragments and predicts a \emph{path} to connect them. In addition, we propose a Sequence Maximum a Posteriori (SeqMAP) decoding algorithm that marginalizes different possible paths and finds the most probable summary satisfying the length budget. Our algorithm is based on beam search, which further facilitates a reranker for performance improvement. Experimental results on the Gigaword and DUC2004 datasets demonstrate our state-of-the-art performance for length-control summarization., Comment: Findings of the Association for Computational Linguistics: EMNLP 2024
- Published
- 2025
18. CAMI: A Counselor Agent Supporting Motivational Interviewing through State Inference and Topic Exploration
- Author
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Yang, Yizhe, Achananuparp, Palakorn, Huang, Heyan, Jiang, Jing, Leng, Kit Phey, Lim, Nicholas Gabriel, Ern, Cameron Tan Shi, and Lim, Ee-peng
- Subjects
Computer Science - Computation and Language - Abstract
Conversational counselor agents have become essential tools for addressing the rising demand for scalable and accessible mental health support. This paper introduces CAMI, a novel automated counselor agent grounded in Motivational Interviewing (MI) -- a client-centered counseling approach designed to address ambivalence and facilitate behavior change. CAMI employs a novel STAR framework, consisting of client's state inference, motivation topic exploration, and response generation modules, leveraging large language models (LLMs). These components work together to evoke change talk, aligning with MI principles and improving counseling outcomes for clients from diverse backgrounds. We evaluate CAMI's performance through both automated and manual evaluations, utilizing simulated clients to assess MI skill competency, client's state inference accuracy, topic exploration proficiency, and overall counseling success. Results show that CAMI not only outperforms several state-of-the-art methods but also shows more realistic counselor-like behavior. Additionally, our ablation study underscores the critical roles of state inference and topic exploration in achieving this performance.
- Published
- 2025
19. Consistent Client Simulation for Motivational Interviewing-based Counseling
- Author
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Yang, Yizhe, Achananuparp, Palakorn, Huang, Heyan, Jiang, Jing, Pinto, John, Giam, Jenny, Leng, Kit Phey, Lim, Nicholas Gabriel, Ern, Cameron Tan Shi, and Lim, Ee-peng
- Subjects
Computer Science - Computation and Language - Abstract
Simulating human clients in mental health counseling is crucial for training and evaluating counselors (both human or simulated) in a scalable manner. Nevertheless, past research on client simulation did not focus on complex conversation tasks such as mental health counseling. In these tasks, the challenge is to ensure that the client's actions (i.e., interactions with the counselor) are consistent with with its stipulated profiles and negative behavior settings. In this paper, we propose a novel framework that supports consistent client simulation for mental health counseling. Our framework tracks the mental state of a simulated client, controls its state transitions, and generates for each state behaviors consistent with the client's motivation, beliefs, preferred plan to change, and receptivity. By varying the client profile and receptivity, we demonstrate that consistent simulated clients for different counseling scenarios can be effectively created. Both our automatic and expert evaluations on the generated counseling sessions also show that our client simulation method achieves higher consistency than previous methods.
- Published
- 2025
20. Including frameworks of public health ethics in computational modelling of infectious disease interventions
- Author
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Zarebski, Alexander E., Tellioglu, Nefel, Stockdale, Jessica E., Spencer, Julie A., KhudaBukhsh, Wasiur R., Miller, Joel C., and Zachreson, Cameron
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Physics - Physics and Society ,Computer Science - Computers and Society ,Quantitative Biology - Populations and Evolution - Abstract
Decisions on public health interventions to control infectious disease are often informed by computational models. Interpreting the predicted outcomes of a public health decision requires not only high-quality modelling, but also an ethical framework for assessing the benefits and harms associated with different options. The design and specification of ethical frameworks matured independently of computational modelling, so many values recognised as important for ethical decision-making are missing from computational models. We demonstrate a proof-of-concept approach to incorporate multiple public health values into the evaluation of a simple computational model for vaccination against a pathogen such as SARS-CoV-2. By examining a bounded space of alternative prioritisations of values (outcome equity and aggregate benefit) we identify value trade-offs, where the outcomes of optimal strategies differ depending on the ethical framework. This work demonstrates an approach to incorporating diverse values into decision criteria used to evaluate outcomes of models of infectious disease interventions., Comment: 33 pages
- Published
- 2025
21. The derangements subgroup in a finite permutation group and the Frobenius--Wielandt Theorem
- Author
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Bailey, R. A., Cameron, P. J., Gavioli, N., and Scoppola, C. M.
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Mathematics - Group Theory ,20B05 20D15 - Abstract
It is known that if the derangements subgroup of a transitive non-regular permutation group is a proper subgroup, then it is a Frobenius--Wielandt kernel, and, conversely, minimal Frobenius--Wielandt kernels are proper derangements subgroups. We present here a short survey of the literature on this topic, and we show that, although there are no restrictions on the structure of the $p$-groups appearing as Frobenius--Wielandt complements, a $p$-group appears as a one-point stabiliser in a transitive non-regular permutation group with a proper derangements subgroup if and only if it satisfies a certain group-theoretic condition.
- Published
- 2025
22. The moduli space of representations of the modular group into $G_2$
- Author
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Babei, Angelica, Fiori, Andrew, and Franc, Cameron
- Subjects
Mathematics - Number Theory ,Mathematics - Algebraic Geometry ,11F06, 14D20 - Abstract
In this paper we construct a large four-dimensional family of representations of the modular group into $G_2$. Precisely, this family is an etale cover of degree $96$ of an open subset of the moduli space of such representations. This moduli space has two main components, of dimensions one and four. The one-dimensional component consists of well-studied rigid representations, in the sense of Katz. We focus on the four-dimensional component which consists of representations that are not rigid. We also provide algebraic conditions to ensure that the specializations surject onto $G_2(\mathbf{F}_p)$ for primes $p\geq 5$. These representations give new examples of $\phi$-congruence subgroups of the modular group as introduced in previous work.
- Published
- 2025
23. Transit-timing variations in the AU Mic system observed with CHEOPS
- Author
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Boldog, Á., Szabó, Gy. M., Kriskovics, L., Borsato, L., Gandolfi, D., Lendl, M., Günther, M. N., Heitzmann, A., Wilson, T. G., Brandeker, A., Garai, Z., Alibert, Y., Alonso, R., Bárczy, T., Navascues, D. Barrado, Barros, S. C. C., Baumjohann, W., Benz, W., Billot, N., Broeg, C., Cameron, A. Collier, Correia, A. C. M., Csizmadia, Sz., Cubillos, P. E., Davies, M. B., Deleuil, M., Deline, A., Demangeon, O. D. S., Demory, B. -O., Derekas, A., Edwards, B., Egger, J. A., Ehrenreich, D., Erikson, A., Fortier, A., Fossati, L., Fridlund, M., Gazeas, K., Gillon, M., Güdel, M., Guterman, P., Helling, Ch., Isaak, K. G., Kiss, L. L., Kopp, E., Korth, J., Lam, K. W. F., Laskar, J., Etangs, A. Lecavelier des, Luntzer, A., Magrin, D., Mantovan, G., Marafatto, L., Maxted, P. F. L., Merín, B., Mordasini, C., Munari, M., Nascimbeni, V., Olofsson, G., Ottensamer, R., Pagano, I., Pallé, E., Peter, G., Piazza, D., Piotto, G., Pollacco, D., Poppenhaeger, K., Queloz, D., Ragazzoni, R., Rando, N., Rauer, H., Ribas, I., Rieder, M., Santos, N. C., Scandariato, G., Ségransan, D., Simon, A. E., Smith, A. M. S., Sousa, S. G., Southworth, R., Stalport, M., Sulis, S., Udry, S., Ulmer-Moll, S., Van Grootel, V., Venturini, J., Villaver, E., Walton, N. A., and Zingales, T.
- Subjects
Astrophysics - Earth and Planetary Astrophysics - Abstract
AU Mic is a very active M dwarf with an edge-on debris disk and two transiting sub-Neptunes with a possible third planetary companion. The two transiting planets exhibit significant transit-timing variations (TTVs) that are caused by the gravitational interaction between the bodies in the system. Using photometrical observations taken with the CHaracterizing ExOPlanet Satellite (CHEOPS), our goal is to constrain the planetary radii, the orbital distances and periods of AU Mic b and c. We aim to determine the superperiod of the TTVs for AU Mic b and to update the transit ephemeris for both planets. Based on the observed TTVs, we study the possible presence of a third planet in the system. We conducted high precision photometric observations with CHEOPS in 2022 and 2023. We used Allesfitter to fit the planetary transits and to constrain the planetary and orbital parameters. We combined our new measurements with results from previous years to determine the periods and amplitudes of the TTVs. We applied dynamical modelling based on TTV measurements from the 2018-2023 period to reconstruct the perceived variations. The orbital distances and periods for AU Mic b and c agree with the results from previous works. However, the values for the planetary radii deviate slightly from previous values, which we attribute to the effect of stellar spots. AU Mic c showed very strong TTVs, with transits that occurred ~80 minutes later in 2023 than in 2021. Through dynamical analysis of the system, we found that the observed TTVs can be explained by a third planet with an orbital period of ~12.6 days and a mass of 0.203+0.022-0.024 M_E. We explored the orbital geometry of the system and found that AU Mic c has a misaligned retrograde orbit. Due limited number of observations the exact configuration and planetary parameters could not be determined. Further monitoring with CHEOPS may improve these results., Comment: 15 pages, 10 figures
- Published
- 2025
24. ASDF: A Compiler for Qwerty, a Basis-Oriented Quantum Programming Language
- Author
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Adams, Austin J., Khan, Sharjeel, Bhamra, Arjun S., Abusaada, Ryan R., Cabrera, Anthony M., Hoechst, Cameron C., Humble, Travis S., Young, Jeffrey S., and Conte, Thomas M.
- Subjects
Quantum Physics ,Computer Science - Programming Languages - Abstract
Qwerty is a high-level quantum programming language built on bases and functions rather than circuits. This new paradigm introduces new challenges in compilation, namely synthesizing circuits from basis translations and automatically specializing adjoint or predicated forms of functions. This paper presents ASDF, an open-source compiler for Qwerty that answers these challenges in compiling basis-oriented languages. Enabled with a novel high-level quantum IR implemented in the MLIR framework, our compiler produces OpenQASM 3 or QIR for either simulation or execution on hardware. Our compiler is evaluated by comparing the fault-tolerant resource requirements of generated circuits with other compilers, finding that ASDF produces circuits with comparable cost to prior circuit-oriented compilers., Comment: 20 pages, 14 figures. To appear in CGO '25
- Published
- 2025
25. General relativistic particle trajectories via quantum mechanical weak values and the Schwarzschild-Alcubierre spacetime
- Author
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Foo, Joshua, Bellamy, Cameron, and Ralph, Timothy C.
- Subjects
Quantum Physics ,General Relativity and Quantum Cosmology ,High Energy Physics - Theory - Abstract
We show that the average trajectories of relativistic quantum particles in Schwarzschild spacetime, obtained via quantum mechanical weak measurements of momentum and energy, are equivalent to the predicted flow lines of probability current in curved spacetime quantum theory. We subsequently demonstrate that these trajectories correspond exactly to classical null geodesics in a hybrid Schwarzschild-Alcubierre spacetime. This threefold equivalence demonstrates how quantum theory in curved spacetime can be formulated via operationally-defined measurements, and that such a theory may be interpreted deterministically, in the spirit of hidden-variable models such as Bohmian mechanics, through the novel connection to an underlying "guiding metric.", Comment: 5+9 pages, 1 figure
- Published
- 2025
26. Self-interfering high harmonic beam arrays driven by Hermite-Gaussian beams
- Author
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Schmidt, David D., Pablos-Marín, José Miguel, Clarke, Cameron, Barolak, Jonathan, Westlake, Nathaniel, Heras, Alba de las, Serrano, Javier, Shevtsov, Sergei, Kazansky, Peter, Adams, Daniel, Hernández-García, Carlos, and Durfee, Charles G.
- Subjects
Physics - Optics - Abstract
The use of structured light to drive highly nonlinear processes in matter not only enables imprinting spatially-resolved properties onto short-wavelength radiation, but also opens alternative avenues for exploring the dynamics of nonlinear laser-matter interactions. In this work, we experimentally and theoretically explore the unique properties of driving high-order harmonic generation (HHG) with Hermite-Gaussian beams. HHG driven by Laguerre-Gauss modes results in harmonics that inherit the azimuthal Laguerre-Gauss modal structure, with their topological charge scaling according to orbital angular momentum conservation. In contrast, when HHG is driven by Hermite-Gauss beams, the harmonic modes do not show a direct correspondence to the driving modal profile. Our experimental measurements using HG$_{01}$ and HG$_{11}$ modes, which are in excellent agreement with our numerical simulations, show that the lobes of the Hermite-Gauss driving beams effectively produce a set of separate phase-locked harmonic beamlets which can interfere downstream. This self-interference, which can be adjusted through the relative position between the gas target and the driving beam focus, can be exploited for precision extreme-ultraviolet interferometry. We demonstrate a simple application to calibrate the dispersion of an extreme-ultraviolet diffraction grating. In addition, we show through simulations that the array of harmonic beamlets can be used as an illumination source for single-shot extreme-ultraviolet ptychography., Comment: 14 pages, 8 figures
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- 2025
27. Periodic Gamma-ray Modulation of the blazar PG 1553+113 Confirmed by Fermi-LAT and Multi-wavelength Observations
- Author
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Abdollahi, S., Baldini, L., Barbiellini, G., Bellazzini, R., Berenji, B., Bissaldi, E., Blandford, R. D., Bonino, R., Bruel, P., Buson, S., Cameron, R. A., Caraveo, P. A., Casaburo, F., Cavazzuti, E., Cheung, C. C., Chiaro, G., Ciprini, S., Cozzolongo, G., Orestano, P. Cristarella, Cutini, S., D'Ammando, F., Di Lalla, N., Dirirsa, F., Di Venere, L., Domínguez, A., Fegan, S. J., Ferrara, E. C., Fiori, A., Fukazawa, Y., Funk, S., Fusco, P., Gargano, F., Garrappa, S., Gasparrini, D., Germani, S., Giglietto, N., Giordano, F., Giroletti, M., Green, D., Grenier, I. A., Guiriec, S., Hays, E., Horan, D., Kuss, M., Larsson, S., Laurenti, M., Li, J., Liodakis, I., Longo, F., Loparco, F., Lott, B., Lovellette, M. N., Lubrano, P., Maldera, S., Malyshev, D., Manfreda, A., Marcotulli, L., Martí-Devesa, G., Mazziotta, M. N., Mereu, I., Michelson, P. F., Mitthumsiri, W., Mizuno, T., Monzani, M. E., Morselli, A., Moskalenko, I. V., Negro, M., Omodei, N., Orienti, M., Orlando, E., Ormes, J. F., Paneque, D., Perri, M., Persic, M., Pesce-Rollins, M., Porter, T. A., Principe, G., Rainò, S., Rando, R., Rani, B., Razzano, M., Reimer, A., Reimer, O., Parkinson, P. M. Saz, Scotton, L., Serini, D., Sesana, A., Sgrò, C., Siskind, E. J., Spandre, G., Spinelli, P., Suson, D. J., Tajima, H., Takahashi, M. N., Tak, D., Thayer, J. B., Thompson, D. J., Torres, D. F., Valverde, J., Verrecchia, F., and Zaharijas, G.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
A 2.1-year periodic oscillation of the gamma-ray flux from the blazar PG 1553+113 has previously been tentatively identified in almost 7 year of data from the Fermi Large Area Telescope. After 15 years of Fermi sky-survey observations, doubling the total time range, we report >7 cycle gamma-ray modulation with an estimated significance of 4 sigma against stochastic red noise. Independent determinations of oscillation period and phase in the earlier and the new data are in close agreement (chance probability <0.01). Pulse timing over the full light curve is also consistent with a coherent periodicity. Multiwavelength new data from Swift X-Ray Telescope, Burst Alert Telescope, and UVOT, and from KAIT, Catalina Sky Survey, All-Sky Automated Survey for Supernovae, and Owens Valley Radio Observatory ground-based observatories as well as archival Rossi X-Ray Timing Explorer satellite-All Sky Monitor data, published optical data of Tuorla, and optical historical Harvard plates data are included in our work. Optical and radio light curves show clear correlations with the gamma-ray modulation, possibly with a nonconstant time lag for the radio flux. We interpret the gamma-ray periodicity as possibly arising from a pulsational accretion flow in a sub-parsec binary supermassive black hole system of elevated mass ratio, with orbital modulation of the supplied material and energy in the jet. Other astrophysical scenarios introduced include instabilities, disk and jet precession, rotation or nutation, and perturbations by massive stars or intermediate-mass black holes in polar orbit., Comment: 23 pages, 14 figures, 20 plots, 1 table, accepted and published by The Astrophysical Journal. Article produced by the Fermi Large Area Telescope (LAT) Collaboration
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- 2025
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28. Enhanced Acoustic Beamforming with Sub-Aperture Angular Multiply and Sum -- in vivo and in Human Demonstration
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Toulemonde, Matthieu, Smith, Cameron A. B., Riemer, Kai, Palanisamy, Priya, Rait, Jaideep Singh, Taylor, Laura, Weinberg, Peter D., Cox, Karina, and Tang, Meng-Xing
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Electrical Engineering and Systems Science - Image and Video Processing ,Electrical Engineering and Systems Science - Signal Processing - Abstract
Power Doppler ultrasound is in widespread clinical use for non-invasive vascular imaging but the most common current method - Delay and Sum (DAS) beamforming - suffers from limited resolution and high side-lobes. Here we propose the Sub-Aperture Angular Multiply and Sum (SAMAS) algorithm; it combines the advantages of two recent non-linear beamformers, Frame Multiply and Sum (FMAS) which uses signal temporal coherence and the acoustic sub-aperture (ASAP) algorithm, which uses signal spatial coherence, respectively. Following in vitro experiments to optimise the algorithm, particularly the use of phase information and sub-aperture pairing, it was evaluated in vivo, first in a rabbit kidney and then in human lymph node, using ultrafast ultrasound images obtained with intravenous contrast agents. The SAMAS algorithm improved the CNR and SNR across all tests, on average raising the CNR by 11 dB and the SNR by 18 dB over DAS in vivo. This work demonstrates a promising vascular imaging method that could have widespread clinical utility.
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- 2025
29. Critical $(P_5,W_4)$-Free Graphs
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Xia, Wen, Jooken, Jorik, Goedgebeur, Jan, Beaton, Iain, Cameron, Ben, and Huang, Shenwei
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Mathematics - Combinatorics - Abstract
A graph $G$ is $k$-vertex-critical if $\chi(G) = k$ but $\chi(G-v)
- Published
- 2025
30. Multi-wavelength observations of a jet launch in real time from the post-changing-look Active Galaxy 1ES 1927+654
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Laha, Sibasish, Meyer, Eileen T., Sadaula, Dev R., Ghosh, Ritesh, Sengupta, Dhrubojyoti, Masterson, Megan, Shuvo, Onic I., Guainazzi, Matteo, Ricci, Claudio, Begelman, Mitchell C., Philippov, Alexander, Mbarek, Rostom, Hankla, Amelia M., Kara, Erin, Panessa, Francesca, Behar, Ehud, Zhang, Haocheng, Pacucci, Fabio, Pal, Main, Ricci, Federica, Villani, Ilaria, Bisogni, Susanna, La Franca, Fabio, Bianchi, Stefano, Bruni, Gabriele, Oates, Samantha, Hahn, Cameron, Nicholl, Matt, Cenko, S. Bradley, Chattopadhyay, Sabyasachi, Gonzalez, Josefa Becerra, Acosta-Pulido, J. A., Rakshit, Suvendu, Svoboda, Jiri, Gallo, Luigi, Ingram, Adam, and Kakkad, Darshan
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies ,High Energy Physics - Phenomenology - Abstract
We present results from a high cadence multi-wavelength observational campaign of the enigmatic changing look AGN 1ES 1927+654 from May 2022- April 2024, coincident with an unprecedented radio flare (an increase in flux by a factor of $\sim 60$ over a few months) and the emergence of a spatially resolved jet at $0.1-0.3$ pc scales (Meyer et al. 2024). Companion work has also detected a recurrent quasi-periodic oscillation (QPO) in the $2-10$ keV band with an increasing frequency ($1-2$ mHz) over the same period (Masterson et al., 2025). During this time, the soft X-rays ($0.3-2$ keV) monotonically increased by a factor of $\sim 8$, while the UV emission remained near-steady with $<30\%$ variation and the $2-10$ keV flux showed variation by a factor $\lesssim 2$. The weak variation of the $2-10$ keV X-ray emission and the stability of the UV emission suggest that the magnetic energy density and accretion rate are relatively unchanged, and that the jet could be launched due to a reconfiguration of the magnetic field (toroidal to poloidal) close to the black hole. Advecting poloidal flux onto the event horizon would trigger the Blandford-Znajek (BZ) mechanism, leading to the onset of the jet. The concurrent softening of the coronal slope (from $\Gamma= 2.70\pm 0.04$ to $\Gamma=3.27\pm 0.04$), the appearance of a QPO, and low coronal temperature ($kT_{e}=8_{-3}^{+8}$ keV) during the radio outburst suggest that the poloidal field reconfiguration can significantly impact coronal properties and thus influence jet dynamics. These extraordinary findings in real time are crucial for coronal and jet plasma studies, particularly as our results are independent of coronal geometry., Comment: Submitted to ApJ after minor referee comments
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- 2025
31. Personalized Graph-Based Retrieval for Large Language Models
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Au, Steven, Dimacali, Cameron J., Pedirappagari, Ojasmitha, Park, Namyong, Dernoncourt, Franck, Wang, Yu, Kanakaris, Nikos, Deilamsalehy, Hanieh, Rossi, Ryan A., and Ahmed, Nesreen K.
- Subjects
Computer Science - Computation and Language - Abstract
As large language models (LLMs) evolve, their ability to deliver personalized and context-aware responses offers transformative potential for improving user experiences. Existing personalization approaches, however, often rely solely on user history to augment the prompt, limiting their effectiveness in generating tailored outputs, especially in cold-start scenarios with sparse data. To address these limitations, we propose Personalized Graph-based Retrieval-Augmented Generation (PGraphRAG), a framework that leverages user-centric knowledge graphs to enrich personalization. By directly integrating structured user knowledge into the retrieval process and augmenting prompts with user-relevant context, PGraphRAG enhances contextual understanding and output quality. We also introduce the Personalized Graph-based Benchmark for Text Generation, designed to evaluate personalized text generation tasks in real-world settings where user history is sparse or unavailable. Experimental results show that PGraphRAG significantly outperforms state-of-the-art personalization methods across diverse tasks, demonstrating the unique advantages of graph-based retrieval for personalization.
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- 2025
32. Microlensing of lensed supernovae Zwicky & iPTF16geu: constraints on the lens galaxy mass slope and dark compact object fraction
- Author
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Arendse, Nikki, Mörtsell, Edvard, Weisenbach, Luke, Hayes, Erin, Thorp, Stephen, Dhawan, Suhail, Goobar, Ariel, Guerrini, Sacha, Hjortlund, Jacob Osman, Johansson, Joel, and Lemon, Cameron
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
To date, only two strongly lensed type Ia supernovae (SNIa) have been discovered with an isolated galaxy acting as the lens: iPTF16geu and SN Zwicky. The observed image fluxes for both lens systems were inconsistent with predictions from a smooth macro lens model. A potential explanation for the anomalous flux ratios is microlensing: additional (de)magnification caused by stars and other compact objects in the lens galaxy. In this work, we combine observations of iPTF16geu and SN Zwicky with simulated microlensing magnification maps, leveraging their standardizable candle properties to constrain the lens galaxy mass slope, $\eta$, and the fraction of dark compact objects, $f_{\rm dc}$. The resulting mass slopes are $\eta = 1.70 \pm 0.07$ for iPTF16geu and $\eta = 1.81 \pm 0.10$ for SN Zwicky. Our results indicate no evidence for a population of dark compact objects, placing upper limits at the $95\%$ confidence level of $f_{\rm dc} < 0.25$ for iPTF16geu and $f_{\rm dc} < 0.47$ for SN Zwicky. Assuming a constant fraction of dark compact objects for both lensed SNe, we obtain $f_{\rm dc} < 0.19$. These results highlight the potential of strongly lensed SNIa to probe the innermost parts of lens galaxies and learn about compact matter., Comment: 19 pages, 12 figures
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- 2025
33. Representation in large language models
- Author
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Yetman, Cameron C.
- Subjects
Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
The extraordinary success of recent Large Language Models (LLMs) on a diverse array of tasks has led to an explosion of scientific and philosophical theorizing aimed at explaining how they do what they do. Unfortunately, disagreement over fundamental theoretical issues has led to stalemate, with entrenched camps of LLM optimists and pessimists often committed to very different views of how these systems work. Overcoming stalemate requires agreement on fundamental questions, and the goal of this paper is to address one such question, namely: is LLM behavior driven partly by representation-based information processing of the sort implicated in biological cognition, or is it driven entirely by processes of memorization and stochastic table look-up? This is a question about what kind of algorithm LLMs implement, and the answer carries serious implications for higher level questions about whether these systems have beliefs, intentions, concepts, knowledge, and understanding. I argue that LLM behavior is partially driven by representation-based information processing, and then I describe and defend a series of practical techniques for investigating these representations and developing explanations on their basis. The resulting account provides a groundwork for future theorizing about language models and their successors., Comment: Draft of paper under review. 27 pages, 2 figures
- Published
- 2025
34. An Accidental Scholar
- Author
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Cameron, Averil
- Published
- 2021
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35. Patristics and Late Antiquity: Partners or Rivals?
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Cameron, Averil
- Published
- 2020
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36. Genders, Sexualities, and Catholic Schools: Towards a Theological Anthropology of Adolescent Flourishing
- Author
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Cynthia L. Cameron
- Abstract
Good religious education needs to be rooted in a robust theological anthropology. The Roman Catholic Church's gender complementarity approach is inadequate for accompanying adolescents in Catholic schools as they engage in questions of gender and sexuality; instead, educators need a theological anthropology oriented towards adolescent flourishing. To construct a more capacious theological anthropological approach, one that is still authentically Catholic and rooted in the Church's official documents, this essay turns to Pope Francis' "Christus Vivit" and "Fratelli Tutti." From Francis' concern for mercy and accompaniment, a theological approach to the goodness of adolescence is described, which can ground theological reflection on gender and sexuality in love and human dignity, rather than shame and exclusion.
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- 2025
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37. Racialized Spatial Imaginaries: Authoring an Elementary School Teacher of Engineering Identity
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Christopher Wright, Monet Harbison, Eli Tucker-Raymond, Kareem Edouard, Sinead Meehan, Tajma Cameron, and George Schafer
- Abstract
Engineering education research has highlighted the importance of examining, understanding, and supporting teacher learning and identity development, particularly for those that hold marginalized identities. As part of the special issue on Teacher Learning and Organizational Contexts, this study examines the intricate relationship between powered boundaries of race, culture, and space for two Black women teachers in organizational contexts within their school district. Using a racialized spatial imaginaries framework, this research describes how two women authored identities as teachers of engineering and cultivated new engineering related spatial imaginaries for their students. The study found that ideational, material, and relational resources made available across organizational contexts contributed to teachers' authoring identities and how they supported their students. The work illuminates how a spatial imaginaries framework can support critical investigation of teacher identity development and (re)examination of how Black students are positioned in spaces of teacher inquiry.
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- 2025
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38. Research and practice - a conversation
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Jones, Mike, Tropea, Rachel, Barrowcliffe, Rose, Cameron, Annie, Freeman, Elliot, Lowry, James, Loxton, Duncan, and Samaras, Eva
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- 2024
39. An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T.
- Author
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Villarreal, Cameron, Shen, Xin, Alhulail, Ahmad, Buffo, Nicholas, Zhou, Xiaopeng, Pogue, Evan, Özen, Ali, Chiew, Mark, Sawiak, Stephen, Emir, Uzay, and Chan, Deva
- Subjects
Articular cartilage ,Fixed charge density ,Sodium MRI ,Ultrashort echo time ,Humans ,Male ,Female ,Adolescent ,Young Adult ,Adult ,Healthy Volunteers ,Cartilage ,Articular ,Sodium ,Magnetic Resonance Imaging ,Knee Joint ,Retrospective Studies - Abstract
OBJECTIVE: In this work, we evaluate the sodium magnetic resonance imaging (MRI) capabilities of a three-dimensional (3D) dual-echo ultrashort echo time (UTE) sequence with a novel rosette petal trajectory (PETALUTE), in comparison to the 3D density-adapted (DA) radial spokes UTE sequence in human articular cartilage in the knee. MATERIALS AND METHODS: We scanned five healthy subjects using a 3D dual-echo PETALUTE acquisition and two comparable implementations of 3D DA-radial spokes acquisitions, one matching the number of k-space projections (Radial - Matched Spokes) and the other matching the total number of samples (Radial - Matched Samples) acquired in k-space. RESULTS: The PETALUTE acquisition enabled equivalent sodium quantification in articular cartilage volumes of interest (168.8 ± 29.9 mM, mean ± standard deviation) to those derived from the 3D radial acquisitions (171.62 ± 28.7 mM and 149.8 ± 22.2 mM, respectively). We achieved a 41% shorter scan time of 2:06 for 3D PETALUTE, compared to 3:36 for 3D radial acquisitions. We also evaluated the feasibility of further acceleration of the PETALUTE sequence through retrospective compressed sensing with 2 × and 4 × acceleration of the first echo and showed structural similarity of 0.89 ± 0.03 and 0.87 ± 0.03 when compared to non-retrospectively accelerated reconstruction. CONCLUSION: We demonstrate improved scan time with equivalent performance using a 3D dual-echo PETALUTE sequence compared to the 3D DA-radial sequence for sodium MRI of articular cartilage.
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- 2025
40. Case Report of Post-Appendectomy Fungal Osteomyelitis: A Rare Complication in a Healthy Patient
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Juybari, Cameron, Muranyi, Andras, Samones, Emmelyn, and GUPTILL, MINDI
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Fungal osteomyelitis ,appendectomy ,Coccidiodes ,Hematogenous osteomyelitis ,case report - Abstract
Introduction: Osteomyelitis is a bone infection that presents with swelling, erythema, pain, and possible systemic symptoms. Immunocompromised patients are at higher risk of developing osteomyelitis. While bacterial osteomyelitis is the most common source causing infection, fungal osteomyelitis is even more uncommon with very few case reports published. Work up should include imaging studies to investigate infections when there is clinical suspicion for osteomyelitis. Bone biopsy is performed to identify the causative agent with bacterial infections being the most common. Osteomyelitis can be treated both surgically with debridement or amputation and medically with extended courses of antimicrobials or antifungals. Our case describes acute onset fungal foot osteomyelitis after an uncomplicated appendectomy. Case Report: A 19-year-old previously healthy female underwent laparoscopic appendectomy for nonperforated, non-gangrenous appendicitis. Fourteen days later, she developed gradually worsening right foot pain, swelling, and erythema. After multiple failed treatments for the management of osteomyelitis, bone biopsies and courses of antibiotics, patient was ultimately diagnosed with a rare osteomyelitis secondary to Coccidioides species, which was managed and improved with antifungals.Conclusion: Bacterial osteomyelitis has been described in two English case reports as a postoperative complication of appendectomy, particularly when the appendicitis is perforated, gangrenous or purulent. Fungal osteomyelitis is an even rarer cause of postoperative bone infection in immunocompetent patients. The goal for treatment is surgical intervention or pharmacologic management. Emergency Department practitioners should maintain a high suspicion for fungal osteomyelitis in otherwise healthy patients presenting with musculoskeletal complaints, and should consider the possibility of fungal species as the cause.
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- 2025
41. A fire deficit persists across diverse North American forests despite recent increases in area burned.
- Author
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Parks, Sean, Guiterman, Christopher, Margolis, Ellis, Lonergan, Margaret, Whitman, Ellen, Abatzoglou, John, Falk, Donald, Johnston, James, Daniels, Lori, Lafon, Charles, Loehman, Rachel, Kipfmueller, Kurt, Naficy, Cameron, Parisien, Marc-André, Portier, Jeanne, Stambaugh, Michael, Williams, Park, Wion, Andreas, and Yocom, Larissa
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Forests ,Wildfires ,North America ,Trees ,Conservation of Natural Resources ,Fires ,Ecosystem - Abstract
Rapid increases in wildfire area burned across North American forests pose novel challenges for managers and society. Increasing area burned raises questions about whether, and to what degree, contemporary fire regimes (1984-2022) are still departed from historical fire regimes (pre-1880). We use the North American tree-ring fire-scar network (NAFSN), a multi-century record comprising >1800 fire-scar sites spanning diverse forest types, and contemporary fire perimeters to ask whether there is a contemporary fire surplus or fire deficit, and whether recent fire years are unprecedented relative to historical fire regimes. Our results indicate, despite increasing area burned in recent decades, that a widespread fire deficit persists across a range of forest types and recent years with exceptionally high area burned are not unprecedented when considering the multi-century perspective offered by fire-scarred trees. For example, record contemporary fire years such as 2020 burned 6% of NAFSN sites-the historical average-well below the historical maximum of 29% sites that burned in 1748. Although contemporary fire extent is not unprecedented across many North American forests, there is abundant evidence that unprecedented contemporary fire severity is driving forest loss in many ecosystems and adversely impacting human lives, infrastructure, and water supplies.
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- 2025
42. Revealing systematic changes in the transcriptome during the transition from exponential growth to stationary phase.
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Lim, Hyun, Gao, Ye, Rychel, Kevin, Lamoureux, Cameron, Lou, Xuwen, and Palsson, Bernhard
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RNA-sequencing ,independent component analysis ,nutrient starvation ,stationary phase ,stress ,systems biology ,transcriptome ,Transcriptome ,Gene Expression Regulation ,Bacterial ,Sulfur ,Nitrogen ,Carbon ,Escherichia coli K12 ,Gene Regulatory Networks ,Escherichia coli Proteins ,Gene Expression Profiling - Abstract
UNLABELLED: The composition of bacterial transcriptomes is determined by the transcriptional regulatory network (TRN). The TRN regulates the transition from one physiological state to another. Here, we use independent component analysis to monitor the composition of the transcriptome during the transition from the exponential growth phase to the stationary phase. With Escherichia coli K-12 MG1655 as a model strain, we trigger the transition using carbon, nitrogen, and sulfur starvation. We find that (i) the transition to the stationary phase accompanies common transcriptome changes, including increased stringent responses and reduced production of cellular building blocks and energy regardless of the limiting element; (ii) condition-specific changes are strongly associated with transcriptional regulators (e.g., Crp, NtrC, CysB, Cbl) responsible for metabolizing the limiting element; and (iii) the shortage of each limiting element differentially affects the production of amino acids and extracellular polymers. This study demonstrates how the combination of genome-scale datasets and new data analytics reveals the fundamental characteristics of a key transition in the life cycle of bacteria. IMPORTANCE: Nutrient limitations are critical environmental perturbations in bacterial physiology. Despite its importance, a detailed understanding of how bacterial transcriptomes are adjusted has been limited. By utilizing independent component analysis (ICA) to decompose transcriptome data, this study reveals key regulatory events that enable bacteria to adapt to nutrient limitations. The findings not only highlight common responses, such as the stringent response, but also condition-specific regulatory shifts associated with carbon, nitrogen, and sulfur starvation. The insights gained from this work advance our knowledge of bacterial physiology, gene regulation, and metabolic adaptation.
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- 2025
43. Effects of Bleaching on Oxygen Dynamics, Energy Metabolism, and Genotype of Symbiotic Algae in Two Caribbean Coral Species
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Linsmayer, Lauren B, Noel, Samantha K, Leray, Matthieu, Wangpraseurt, Daniel, Hassibi, Cameron, David, Kline I, and Tresguerres, Martin
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reef ,hypoxia ,Warburg ,Orbicella ,Agaricia ,Bocas del Toro - Published
- 2025
44. Draft genome sequences for Neonectria magnoliae and Neonectria punicea, canker pathogens of Liriodendron tulipifera and Acer saccharum in West Virginia
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Petronek, Hannah M, Kasson, Matt T, Metheny, Amy M, Stauder, Cameron M, Lovett, Brian, Lynch, Shannon C, Garnas, Jeff R, Kasson, Lindsay R, and Stajich, Jason E
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Microbiology ,Plant Biology ,Biological Sciences ,Genetics ,Infectious Diseases ,Human Genome ,Biotechnology ,fungi ,Nectriaceae ,canker pathogens ,Hypocreales ,genomics ,Biochemistry and Cell Biology - Abstract
The fungal genus Neonectria contains many phytopathogenic species currently impacting forests and fruit trees worldwide. Despite their importance, a majority of Neonectria spp. lack sufficient genomic resources to resolve suspected cryptic species. Here, we report draft genomes and assemblies for Neonectria magnoliae NRRL 64651 and Neonectria punicea NRRL 64653.
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- 2025
45. Evaluation of Outcomes Following Arthroscopic Treatment of Femoroacetabular Impingement Syndrome Across Different Surgeons, Surgical Techniques, and Postoperative Protocols: A Multi-institutional Study.
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Spencer, Andrew, Newby, Nathan, Nosrat, Cameron, Wong, Stephanie, Zhang, Alan, and Hagen, Mia
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femoroacetabular impingement ,groin pain ,hip ,hip arthroscopy ,hip/pelvis/thigh ,multicenter outcomes - Abstract
BACKGROUND: Femoroacetabular impingement syndrome (FAIS) is frequently treated arthroscopically with osteoplasty and labral repair. Surgical preferences vary in terms of equipment, technique, and postoperative protocol. Patient-reported outcome measures (PROMs) are valuable tools to assess outcomes across different institutions. PURPOSE: To compare PROMs after FAIS arthroscopy and evaluate the impact on postoperative outcomes with independent surgeons utilizing different surgical techniques and postoperative protocols. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: Prospective data were collected from patients with a 2-year follow-up after arthroscopic FAIS treatment by 2 orthopaedic surgeons from different states, each attending different sports medicine fellowships. Patients were matched according to age, sex, and body mass index. Data included patient characteristics, surgical findings, and the Hip disability and Osteoarthritis Outcome Score (HOOS) preoperatively and 2 years postoperatively. Patients with revision surgery, concomitant procedures, or incomplete pre- and postoperative data were excluded. Surgeon A utilized interportal capsulotomy, capsular repair, all-suture anchors, and a postoperative hip brace. Surgeon B employed periportal capsulotomy without repair, polyether ether ketone suture anchors, and no brace. The 2 high-volume arthroscopists (>100 hips/year) performed osteoplasty and labral repair and used a large perineal post. Cohorts were analyzed with appropriate t tests, with significance set at P < .05. The percentage of patients achieving minimal clinically important difference (MCID) was calculated using Pearson chi-square tests. RESULTS: A total of 176 hips (100 women, 76 men) were included, with 88 matched patients from each institution. The mean age was 33.7 years and the body mass index was 26.3 kg/m2. Both cohorts significantly improved in all 5 HOOS subscales 2 years after surgery. When comparing the mean change in PROMs and the percentage of patients achieving the MCID, differences were only observed in the HOOS-Sports subscale (cohort A: 25.3 ± 29.7 vs cohort B: 34.3 ± 29.7; P = .048; MCID achieved in 57% of patients vs 76%; P = .01). CONCLUSION: This prospective cohort study on arthroscopic FAIS treatment indicates that matched patient cohorts from different institutions show similarly improved PROMs at 2 years. This study suggests consistent patient outcomes across sites despite geography, surgeon, training, surgical technique, implants, and postoperative protocol.
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- 2025
46. Spatiotemporal Synchrony of Climate and Fire Occurrence Across North American Forests (1750–1880)
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Margolis, Ellis, Wion, Andreas, Abatzoglou, John, Daniels, Lori, Falk, Donald, Guiterman, Chris, Johnston, James, Kipfmueller, Kurt, Lafon, Charles, Loehman, Rachel, Lonergan, Maggie, Naficy, Cameron, Parisien, Marc‐André, Parks, Sean, Portier, Jeanne, Stambaugh, Michael, Whitman, Ellen, Williams, A Park, and Yocom, Larissa
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Ecological Applications ,Environmental Sciences ,Climate Action ,climate ,fire ,fire scar ,regionalisation ,synchrony ,tree ring ,Physical Geography and Environmental Geoscience ,Ecology ,Ecological applications ,Environmental management - Abstract
ABSTRACT: Aim: Increasing aridity has driven widespread synchronous fire occurrence in recent decades across North America. The lack of historical (pre‐1880) fire records limits our ability to understand long‐term continental fire‐climate dynamics. The goal of this study is to use tree‐ring reconstructions to determine the relationships between spatiotemporal patterns in historical climate and widespread fire occurrence in North American forests, and whether they are stable through time. This information will address a major knowledge gap required to inform projections of future fire. Location: North American Forests. Time Period: 1750–1880 CE. Major Taxa Studied: Trees. Methods: We applied regionalisation methods to tree‐ring reconstructions of historical summer soil moisture and annual fire occurrence to independently identify broad‐ and fine‐scale climate and fire regions based on common inter‐annual variability. We then tested whether the regions were stable through time and for spatial correspondence between the climate and fire regions. Last, we used correlation analysis to quantify the strength of the fire‐climate associations through time. Results: We found that broad‐scale historical patterns in climate and fire have strong spatial coherence. Although climate and fire regions vary over time, large core areas of the regions were stable. The association between climate and fire varied through time and was strongest in western North America, likely due to a combination of factors, such as the magnitude of drought frequency and severity, as well as varying use of fire by human communities. Main Conclusions: The historical perspective gained through tree‐ring reconstructions of climate and fire patterns and their association suggests that climate‐driven synchrony of fire across large areas of the continent in recent decades is not unprecedented, will likely continue into the future, and may exhibit similar spatial patterns.
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- 2025
47. Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors
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Patel, Deepak T, Stogios, Peter J, Jaroszewski, Lukasz, Urbanus, Malene L, Sedova, Mayya, Semper, Cameron, Le, Cathy, Takkouche, Abraham, Ichii, Keita, Innabi, Julie, Patel, Dhruvin H, Ensminger, Alexander W, Godzik, Adam, and Savchenko, Alexei
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Biochemistry and Cell Biology ,Biological Sciences ,Infectious Diseases ,Pneumonia & Influenza ,Rare Diseases ,Lung ,Pneumonia ,Infection ,Legionella pneumophila ,Bacterial Proteins ,Protein Domains ,Saccharomyces cerevisiae ,Type IV Secretion Systems ,Bacterial Effectors ,Legionella pneumophila ,Protein Modeling ,Yeast Toxicity ,Cryptic Domains ,Other Biological Sciences ,Bioinformatics ,Biochemistry and cell biology - Abstract
Legionella pneumophila utilizes the Dot/Icm type IVB secretion system to deliver hundreds of effector proteins inside eukaryotic cells to ensure intracellular replication. Our understanding of the molecular functions of the largest pathogenic arsenal known to the bacterial world remains incomplete. By leveraging advancements in 3D protein structure prediction, we provide a comprehensive structural analysis of 368 L. pneumophila effectors, representing a global atlas of predicted functional domains summarized in a database ( https://pathogens3d.org/legionella-pneumophila ). Our analysis identified 157 types of diverse functional domains in 287 effectors, including 159 effectors with no prior functional annotations. Furthermore, we identified 35 cryptic domains in 30 effector models that have no similarity with experimentally structurally characterized proteins, thus, hinting at novel functionalities. Using this analysis, we demonstrate the activity of thirteen functional domains, including three cryptic domains, predicted in L. pneumophila effectors to cause growth defects in the Saccharomyces cerevisiae model system. This illustrates an emerging strategy of exploring synergies between predictions and targeted experimental approaches in elucidating novel effector activities involved in infection.
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- 2025
48. A synchronous lesion: Papillary renal cell carcinoma mistaken as an adrenal gland mass.
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Fateri, Cameron, Chen, Kasha, Sun, Shawn, OConnell, Ryan, and Houshyar, Roozbeh
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Adrenal ,CT ,Metastasis ,Papillary ,RCC - Abstract
In this case report, we describe a diagnosis of papillary renal cell carcinoma in a 76-year-old male patient who was incidentally found to have a left adrenal mass during routine aneurysm surveillance. Computed tomography demonstrated a left adrenal mass and left renal structure which was concerning for renal cell carcinoma. He underwent left adrenalectomy and initial histopathology demonstrated papillary renal cell carcinoma. He subsequently underwent left radical nephrectomy with lymph node dissection. Histopathological analysis of the removed left renal and nodal specimens revealed papillary renal cell carcinoma with lymph node metastasis. However, re-review of the adrenal pathology slides determined the specimen as represented by primary kidney tumor and not adrenal metastasis. This report reviews the presentation and radiological findings of synchronous papillary renal cell carcinoma and differential diagnosis for indeterminate adrenal mass on computed tomography.
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- 2025
49. Deep learning optimal molecular scintillators for dark matter direct detection
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Cook, Cameron, Blanco, Carlos, and Smirnov, Juri
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High Energy Physics - Phenomenology ,Condensed Matter - Materials Science ,High Energy Physics - Experiment ,High Energy Physics - Theory ,Physics - Instrumentation and Detectors - Abstract
Direct searches for sub-GeV dark matter are limited by the intrinsic quantum properties of the target material. In this proof-of-concept study, we argue that this problem is particularly well suited for machine learning. We demonstrate that a simple neural architecture consisting of a variational autoencoder and a multi-layer perceptron can efficiently generate unique molecules with desired properties. In specific, the energy threshold and signal (quantum) efficiency determine the minimum mass and cross section to which a detector can be sensitive. Organic molecules present a particularly interesting class of materials with intrinsically anisotropic electronic responses and $\mathcal{O}$(few) eV excitation energies. However, the space of possible organic compounds is intractably large, which makes traditional database screening challenging. We adopt excitation energies and proxy transition matrix elements as target properties learned by our network. Our model is able to generate molecules that are not in even the most expansive quantum chemistry databases and predict their relevant properties for high-throughput and efficient screening. Following a massive generation of novel molecules, we use clustering analysis to identify some of the most promising molecular structures that optimise the desired molecular properties for dark matter detection.
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- 2024
50. A family of simplicial resolutions which are DG-algebras
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Cameron, James, Chau, Trung, Maitra, Sarasij, and Tribone, Tim
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Mathematics - Commutative Algebra ,Primary: 13D02, 05E40, Secondary: 16W50, 13F55 - Abstract
Each monomial ideal over a polynomial ring admits a free resolution which has the structure of a DG-algebra, namely, the Taylor resolution. A pivot resolution of a monomial ideal, which we introduce, is a resolution that is always shorter than the Taylor resolution (unless the Taylor resolution is as short as possible) but still retains a DG-algebra structure. We study the basic properties of this family of resolutions including a characterization of when the construction is minimal. Following the work of Sobieska, we use the explicit nature of pivot resolutions to give formulae for the Eisenbud-Shamash construction of a free resolution of a given monomial ideal over complete intersections., Comment: are welcome. 18 pages. Dedicated to J\"urgen Herzog
- Published
- 2024
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