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203 results on '"Camisaschi, Chiara"'

1. NaCl enhances CD8+ T cell effector functions in cancer immunotherapy

Author

Scirgolea, Caterina, Sottile, Rosa, De Luca, Marco, Susana, Alberto, Carnevale, Silvia, Puccio, Simone, Ferrari, Valentina, Lise, Veronica, Contarini, Giorgia, Scarpa, Alice, Scamardella, Eloise, Feno, Simona, Camisaschi, Chiara, De Simone, Gabriele, Basso, Gianluca, Giuliano, Desiree, Mazza, Emilia Maria Cristina, Gattinoni, Luca, Roychoudhuri, Rahul, Voulaz, Emanuele, Di Mitri, Diletta, Simonelli, Matteo, Losurdo, Agnese, Pozzi, Davide, Tsui, Carlson, Kallies, Axel, Timo, Sara, Martano, Giuseppe, Barberis, Elettra, Manfredi, Marcello, Rescigno, Maria, Jaillon, Sebastien, and Lugli, Enrico

Published
2024
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2. C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer

Author

Portale, Federica, Carriero, Roberta, Iovino, Marta, Kunderfranco, Paolo, Pandini, Marta, Marelli, Giulia, Morina, Nicolò, Lazzeri, Massimo, Casale, Paolo, Colombo, Piergiuseppe, De Simone, Gabriele, Camisaschi, Chiara, Lugli, Enrico, Basso, Gianluca, Cibella, Javier, Marchini, Sergio, Bordi, Matteo, Meregalli, Greta, Garbin, Anna, Dambra, Monica, Magrini, Elena, Rackwitz, Wiebke, Cecconi, Francesco, Corbelli, Alessandro, Fiordaliso, Fabio, Eitler, Jiri, Tonn, Torsten, and Di Mitri, Diletta

Published
2024
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4. Parkin activates innate immunity and promotes antitumor immune responses

Author

Perego, Michela, Yeon, Minjeong, Agarwal, Ekta, Milcarek, Andrew T., Bertolini, Irene, Camisaschi, Chiara, Ghosh, Jagadish C., Tang, Hsin-Yao, Grandvaux, Nathalie, Ruscetti, Marcus, Kossenkov, Andrew V., Preston-Alp, Sarah, Tempera, Italo, Auslander, Noam, and Altieri, Dario C.

Subjects
Immune response -- Evaluation, Cancer -- Care and treatment, Ligases -- Identification and classification -- Health aspects, Health care industry
Abstract

The activation of innate immunity and associated interferon (IFN) signaling have been implicated in cancer, but the regulators are elusive and links to tumor suppression remain undetermined. Here, we found that Parkin, an E3 ubiquitin ligase altered in Parkinson's Disease, was epigenetically silenced in cancer and its reexpression by clinically approved demethylating therapy stimulated transcription of a potent IFN response in tumor cells. This pathway required Parkin E3 ubiquitin ligase activity, involved the subcellular trafficking and release of the alarmin High Mobility Group Box 1 (HMGB1) and was associated with inhibition of NF-kB gene expression. In turn, Parkin-expressing cells released an IFN secretome that upregulated effector and cytotoxic [CD8.sup.+] T cell markers, lowered the expression of immune inhibitory receptors TIM3 and LAG3, and stimulated high content of the self renewal/stem cell factor, TCF1. PRKN-induced [CD8.sup.+] T cells selectively accumulated in the microenvironment and inhibited transgenic and syngeneic tumor growth in vivo. Therefore, Parkin is an epigenetically regulated activator of innate immunity and dual mode tumor suppressor, inhibiting intrinsic tumor traits of metabolism and cell invasion, while simultaneously reinvigorating CD8 T cell functions in the microenvironment., Introduction The transcriptional induction of interferons (IFN) and their downstream IFN-stimulated genes (ISG) is a formidable host defense mechanism against pathogenic infections, mostly viruses (1). Identified as innate immunity, this [...]

Published
2024
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5. Reduction of Staphylococcus epidermidis in the mammary tumor microbiota induces antitumor immunity and decreases breast cancer aggressiveness

Author

Bernardo, Giancarla, Le Noci, Valentino, Ottaviano, Emerenziana, De Cecco, Loris, Camisaschi, Chiara, Guglielmetti, Simone, Di Modica, Martina, Gargari, Giorgio, Bianchi, Francesca, Indino, Serena, Sartori, Patrizia, Borghi, Elisa, Sommariva, Michele, Tagliabue, Elda, Triulzi, Tiziana, and Sfondrini, Lucia

Published
2023
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7. A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer

Author

Bertolini, Giulia, Cancila, Valeria, Milione, Massimo, Lo Russo, Giuseppe, Fortunato, Orazio, Zaffaroni, Nadia, Tortoreto, Monica, Centonze, Giovanni, Chiodoni, Claudia, Facchinetti, Federica, Pollaci, Giuliana, Taiè, Giulia, Giovinazzo, Francesca, Moro, Massimo, Camisaschi, Chiara, De Toma, Alessandro, D’Alterio, Crescenzo, Pastorino, Ugo, Tripodo, Claudio, Scala, Stefania, Sozzi, Gabriella, and Roz, Luca

Published
2021
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8. Immunological characterization of a long-lasting response in a patient with metastatic triple-negative breast cancer treated with PD-1 and LAG-3 blockade

Author

Rivoltini, L, Camisaschi, C, Fucà, G, Paolini, B, Vergani, B, Beretta, V, Damian, S, Duca, M, Cresta, S, Magni, M, Leone, B, Castelli, C, de Braud, F, De Santis, F, Di Nicola, M, Rivoltini, Licia, Camisaschi, Chiara, Fucà, Giovanni, Paolini, Biagio, Vergani, Barbara, Beretta, Valeria, Damian, Silvia, Duca, Matteo, Cresta, Sara, Magni, Michele, Leone, Biagio Eugenio, Castelli, Chiara, de Braud, Filippo, De Santis, Francesca, Di Nicola, Massimo, Rivoltini, L, Camisaschi, C, Fucà, G, Paolini, B, Vergani, B, Beretta, V, Damian, S, Duca, M, Cresta, S, Magni, M, Leone, B, Castelli, C, de Braud, F, De Santis, F, Di Nicola, M, Rivoltini, Licia, Camisaschi, Chiara, Fucà, Giovanni, Paolini, Biagio, Vergani, Barbara, Beretta, Valeria, Damian, Silvia, Duca, Matteo, Cresta, Sara, Magni, Michele, Leone, Biagio Eugenio, Castelli, Chiara, de Braud, Filippo, De Santis, Francesca, and Di Nicola, Massimo

Abstract

In patients with advanced triple-negative breast cancer (TNBC), translational research efforts are needed to improve the clinical efficacy of immunotherapy with checkpoint inhibitors. Here, we report on the immunological characterization of an exceptional, long-lasting, tumor complete response in a patient with metastatic TNBC treated with dual PD-1 and LAG-3 blockade within the phase I/II study CLAG525X2101C (NCT02460224) The pre-treatment tumor biopsy revealed the presence of a CD3+ and CD8+ cell infiltrate, with few PD1+ cells, rare CD4+ cells, and an absence of both NK cells and LAG3 expression. Conversely, tumor cells exhibited positive staining for the three primary LAG-3 ligands (HLA-DR, FGL-1, and galectin-3), while being negative for PD-L1. In peripheral blood, baseline expression of LAG-3 and PD-1 was observed in circulating immune cells. Following treatment initiation, there was a rapid increase in proliferating granzyme-B+ NK and T cells, including CD4+ T cells, alongside a reduction in myeloid-derived suppressor cells. The role of LAG-3 expression on circulating NK cells, as well as the expression of LAG-3 ligands on tumor cells and the early modulation of circulating cytotoxic CD4+ T cells warrant further investigation as exploitable predictive biomarkers for dual PD-1 and LAG-3 blockade. Trial registration: NCT02460224. Registered 02/06/2015.

Published
2024

11. Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment

Author

Tazzari, Marcella, Indio, Valentina, Vergani, Barbara, De Cecco, Loris, Rini, Francesca, Negri, Tiziana, Camisaschi, Chiara, Fiore, Marco, Stacchiotti, Silvia, Dagrada, G. Paolo, Casali, Paolo G., Gronchi, Alessandro, Astolfi, Annalisa, Pantaleo, Maria A., Villa, Antonello, Lombardo, Claudia, Arienti, Flavio, Pilotti, Silvana, Rivoltini, Licia, and Castelli, Chiara

Published
2017
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13. NaCl enhances CD8+T cell effector functions in cancer immunotherapy

Author

Scirgolea, Caterina, Sottile, Rosa, De Luca, Marco, Susana, Alberto, Carnevale, Silvia, Puccio, Simone, Ferrari, Valentina, Lise, Veronica, Contarini, Giorgia, Scarpa, Alice, Scamardella, Eloise, Feno, Simona, Camisaschi, Chiara, De Simone, Gabriele, Basso, Gianluca, Giuliano, Desiree, Mazza, Emilia Maria Cristina, Gattinoni, Luca, Roychoudhuri, Rahul, Voulaz, Emanuele, Di Mitri, Diletta, Simonelli, Matteo, Losurdo, Agnese, Pozzi, Davide, Tsui, Carlson, Kallies, Axel, Timo, Sara, Martano, Giuseppe, Barberis, Elettra, Manfredi, Marcello, Rescigno, Maria, Jaillon, Sebastien, and Lugli, Enrico

Abstract

CD8+T cells control tumors but inevitably become dysfunctional in the tumor microenvironment. Here, we show that sodium chloride (NaCl) counteracts T cell dysfunction to promote cancer regression. NaCl supplementation during CD8+T cell culture induced effector differentiation, IFN-γ production and cytotoxicity while maintaining the gene networks responsible for stem-like plasticity. Accordingly, adoptive transfer of tumor-specific T cells resulted in superior anti-tumor immunity in a humanized mouse model. In mice, a high-salt diet reduced the growth of experimental tumors in a CD8+T cell-dependent manner by inhibiting terminal differentiation and enhancing the effector potency of CD8+T cells. Mechanistically, NaCl enhanced glutamine consumption, which was critical for transcriptional, epigenetic and functional reprogramming. In humans, CD8+T cells undergoing antigen recognition in tumors and predicting favorable responses to checkpoint blockade immunotherapy resembled those induced by NaCl. Thus, NaCl metabolism is a regulator of CD8+T cell effector function, with potential implications for cancer immunotherapy.

Published
2024
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18. Supplementary Table 2 from Limited Induction of Tumor Cross-Reactive T Cells without a Measurable Clinical Benefit in Early Melanoma Patients Vaccinated with Human Leukocyte Antigen Class I–Modified Peptides

Author

Filipazzi, Paola, primary, Pilla, Lorenzo, primary, Mariani, Luigi, primary, Patuzzo, Roberto, primary, Castelli, Chiara, primary, Camisaschi, Chiara, primary, Maurichi, Andrea, primary, Cova, Agata, primary, Rigamonti, Gianluigi, primary, Giardino, Felicetta, primary, Di Florio, Annabella, primary, Asioli, Marco, primary, Frati, Paola, primary, Sovena, Gloria, primary, Squarcina, Paola, primary, Maio, Michele, primary, Danielli, Riccardo, primary, Chiarion-Sileni, Vanna, primary, Villa, Antonello, primary, Lombardo, Claudia, primary, Tragni, Gabrina, primary, Santinami, Mario, primary, Parmiani, Giorgio, primary, and Rivoltini, Licia, primary

Published
2023
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21. Supplementary Table 1 from Limited Induction of Tumor Cross-Reactive T Cells without a Measurable Clinical Benefit in Early Melanoma Patients Vaccinated with Human Leukocyte Antigen Class I–Modified Peptides

Author

Filipazzi, Paola, primary, Pilla, Lorenzo, primary, Mariani, Luigi, primary, Patuzzo, Roberto, primary, Castelli, Chiara, primary, Camisaschi, Chiara, primary, Maurichi, Andrea, primary, Cova, Agata, primary, Rigamonti, Gianluigi, primary, Giardino, Felicetta, primary, Di Florio, Annabella, primary, Asioli, Marco, primary, Frati, Paola, primary, Sovena, Gloria, primary, Squarcina, Paola, primary, Maio, Michele, primary, Danielli, Riccardo, primary, Chiarion-Sileni, Vanna, primary, Villa, Antonello, primary, Lombardo, Claudia, primary, Tragni, Gabrina, primary, Santinami, Mario, primary, Parmiani, Giorgio, primary, and Rivoltini, Licia, primary

Published
2023
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22. Supplementary Figure 4 from Limited Induction of Tumor Cross-Reactive T Cells without a Measurable Clinical Benefit in Early Melanoma Patients Vaccinated with Human Leukocyte Antigen Class I–Modified Peptides

Author

Filipazzi, Paola, primary, Pilla, Lorenzo, primary, Mariani, Luigi, primary, Patuzzo, Roberto, primary, Castelli, Chiara, primary, Camisaschi, Chiara, primary, Maurichi, Andrea, primary, Cova, Agata, primary, Rigamonti, Gianluigi, primary, Giardino, Felicetta, primary, Di Florio, Annabella, primary, Asioli, Marco, primary, Frati, Paola, primary, Sovena, Gloria, primary, Squarcina, Paola, primary, Maio, Michele, primary, Danielli, Riccardo, primary, Chiarion-Sileni, Vanna, primary, Villa, Antonello, primary, Lombardo, Claudia, primary, Tragni, Gabrina, primary, Santinami, Mario, primary, Parmiani, Giorgio, primary, and Rivoltini, Licia, primary

Published
2023
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23. Supplementary Figure 3 from Limited Induction of Tumor Cross-Reactive T Cells without a Measurable Clinical Benefit in Early Melanoma Patients Vaccinated with Human Leukocyte Antigen Class I–Modified Peptides

Author

Filipazzi, Paola, primary, Pilla, Lorenzo, primary, Mariani, Luigi, primary, Patuzzo, Roberto, primary, Castelli, Chiara, primary, Camisaschi, Chiara, primary, Maurichi, Andrea, primary, Cova, Agata, primary, Rigamonti, Gianluigi, primary, Giardino, Felicetta, primary, Di Florio, Annabella, primary, Asioli, Marco, primary, Frati, Paola, primary, Sovena, Gloria, primary, Squarcina, Paola, primary, Maio, Michele, primary, Danielli, Riccardo, primary, Chiarion-Sileni, Vanna, primary, Villa, Antonello, primary, Lombardo, Claudia, primary, Tragni, Gabrina, primary, Santinami, Mario, primary, Parmiani, Giorgio, primary, and Rivoltini, Licia, primary

Published
2023
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24. Supplementary Figure Legend from Limited Induction of Tumor Cross-Reactive T Cells without a Measurable Clinical Benefit in Early Melanoma Patients Vaccinated with Human Leukocyte Antigen Class I–Modified Peptides

Author

Filipazzi, Paola, primary, Pilla, Lorenzo, primary, Mariani, Luigi, primary, Patuzzo, Roberto, primary, Castelli, Chiara, primary, Camisaschi, Chiara, primary, Maurichi, Andrea, primary, Cova, Agata, primary, Rigamonti, Gianluigi, primary, Giardino, Felicetta, primary, Di Florio, Annabella, primary, Asioli, Marco, primary, Frati, Paola, primary, Sovena, Gloria, primary, Squarcina, Paola, primary, Maio, Michele, primary, Danielli, Riccardo, primary, Chiarion-Sileni, Vanna, primary, Villa, Antonello, primary, Lombardo, Claudia, primary, Tragni, Gabrina, primary, Santinami, Mario, primary, Parmiani, Giorgio, primary, and Rivoltini, Licia, primary

Published
2023
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25. Supplementary Figure 5 from Limited Induction of Tumor Cross-Reactive T Cells without a Measurable Clinical Benefit in Early Melanoma Patients Vaccinated with Human Leukocyte Antigen Class I–Modified Peptides

Author

Filipazzi, Paola, primary, Pilla, Lorenzo, primary, Mariani, Luigi, primary, Patuzzo, Roberto, primary, Castelli, Chiara, primary, Camisaschi, Chiara, primary, Maurichi, Andrea, primary, Cova, Agata, primary, Rigamonti, Gianluigi, primary, Giardino, Felicetta, primary, Di Florio, Annabella, primary, Asioli, Marco, primary, Frati, Paola, primary, Sovena, Gloria, primary, Squarcina, Paola, primary, Maio, Michele, primary, Danielli, Riccardo, primary, Chiarion-Sileni, Vanna, primary, Villa, Antonello, primary, Lombardo, Claudia, primary, Tragni, Gabrina, primary, Santinami, Mario, primary, Parmiani, Giorgio, primary, and Rivoltini, Licia, primary

Published
2023
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27. Supplementary Figure 1 from Limited Induction of Tumor Cross-Reactive T Cells without a Measurable Clinical Benefit in Early Melanoma Patients Vaccinated with Human Leukocyte Antigen Class I–Modified Peptides

Author

Filipazzi, Paola, primary, Pilla, Lorenzo, primary, Mariani, Luigi, primary, Patuzzo, Roberto, primary, Castelli, Chiara, primary, Camisaschi, Chiara, primary, Maurichi, Andrea, primary, Cova, Agata, primary, Rigamonti, Gianluigi, primary, Giardino, Felicetta, primary, Di Florio, Annabella, primary, Asioli, Marco, primary, Frati, Paola, primary, Sovena, Gloria, primary, Squarcina, Paola, primary, Maio, Michele, primary, Danielli, Riccardo, primary, Chiarion-Sileni, Vanna, primary, Villa, Antonello, primary, Lombardo, Claudia, primary, Tragni, Gabrina, primary, Santinami, Mario, primary, Parmiani, Giorgio, primary, and Rivoltini, Licia, primary

Published
2023
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28. Supplementary Figure 2 from Limited Induction of Tumor Cross-Reactive T Cells without a Measurable Clinical Benefit in Early Melanoma Patients Vaccinated with Human Leukocyte Antigen Class I–Modified Peptides

Author

Filipazzi, Paola, primary, Pilla, Lorenzo, primary, Mariani, Luigi, primary, Patuzzo, Roberto, primary, Castelli, Chiara, primary, Camisaschi, Chiara, primary, Maurichi, Andrea, primary, Cova, Agata, primary, Rigamonti, Gianluigi, primary, Giardino, Felicetta, primary, Di Florio, Annabella, primary, Asioli, Marco, primary, Frati, Paola, primary, Sovena, Gloria, primary, Squarcina, Paola, primary, Maio, Michele, primary, Danielli, Riccardo, primary, Chiarion-Sileni, Vanna, primary, Villa, Antonello, primary, Lombardo, Claudia, primary, Tragni, Gabrina, primary, Santinami, Mario, primary, Parmiani, Giorgio, primary, and Rivoltini, Licia, primary

Published
2023
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29. Data from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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30. Supplementary Table 1 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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31. Supplementary Figure 1 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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32. Supplementary Table 5 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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33. Supplementary Table 4 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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34. Supplementary Figure 2 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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38. Supplementary Figure 3 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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40. Supplementary Methods from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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41. Supplementary Table 3 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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42. Supplementary Table 2 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression

Author

Vallacchi, Viviana, primary, Vergani, Elisabetta, primary, Camisaschi, Chiara, primary, Deho, Paola, primary, Cabras, Antonello D., primary, Sensi, Marialuisa, primary, De Cecco, Loris, primary, Bassani, Niccolò, primary, Ambrogi, Federico, primary, Carbone, Antonino, primary, Crippa, Federica, primary, Vergani, Barbara, primary, Frati, Paola, primary, Arienti, Flavio, primary, Patuzzo, Roberto, primary, Villa, Antonello, primary, Biganzoli, Elia, primary, Canevari, Silvana, primary, Santinami, Mario, primary, Castelli, Chiara, primary, Rivoltini, Licia, primary, and Rodolfo, Monica, primary

Published
2023
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48. Effects of cyclophosphamide and IL-2 on regulatory CD4+ T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response

Author

Camisaschi, Chiara, Filipazzi, Paola, Tazzari, Marcella, Casati, Chiara, Beretta, Valeria, Pilla, Lorenzo, Patuzzo, Roberto, Maurichi, Andrea, Cova, Agata, Maio, Michele, Chiarion-Sileni, Vanna, Tragni, Gabrina, Santinami, Mario, Vergani, Barbara, Villa, Antonello, Berti, Emilio, Umansky, Ludmila, Beckhove, Philipp, Umansky, Viktor, Parmiani, Giorgio, Rivoltini, Licia, and Castelli, Chiara

Published
2013
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50. Abstract 1653: A single-cell atlas of the effect of chemotherapeutics over intratumoral immune cells reveals that combining an alkylating agent and a vinca alkaloid can activate antigen presenting cells and increase tcf1+ stem-like CD8+ T-cells, thus improving anti-PD-1 efficacy in triple negative breast cancer and lymphoma

Author

Falvo, Paolo, primary, Orecchioni, Stefania, additional, Hillje, Roman, additional, Raveane, Alessandro, additional, Mitola, Giulia, additional, Mancuso, Patrizia, additional, Camisaschi, Chiara, additional, Luzi, Lucilla, additional, Pelicci, PierGiuseppe, additional, and Bertolini, Francesco, additional

Published
2021
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