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6 results on '"Campbell, Connie S."'

1. The Complete Genome Sequence of Bacillus thuringiensis Al Hakam

Author

Challacombe, Jean F., Altherr, Michael R., Xie, Gary, Bhotika, Smriti S., Brown, Nancy, Bruce, David, Campbell, Connie S., Campbell, Mary L., Chen, Jin, Chertkov, Olga, Cleland, Cathy, Dimitrijevic, Mira, Doggett, Norman A., Fawcett, John J., Glavina, Tijana, Goodwin, Lynne A., Green, Lance D., Han, Cliff S., Hill, Karen K., Hitchcock, Penny, Jackson, Paul J., Keim, Paul, Kewalramani, Avinash Ramesh, Longmire, Jon, Lucas, Susan, Malfatti, Stephanie, Martinez, Diego, McMurry, Kim, Meincke, Linda J., Misra, Monica, Moseman, Bernice L., Mundt, Mark, Munk, A. Christine, Okinaka, Richard T., Parson-Quintana, B., Reilly, Lee Philip, Richardson, Paul, Robinson, Donna L., Rubin, Eddy, Saunders, Elizabeth, Tapia, Roxanne, Tesmer, Judith G., Thayer, Nina, Thompson, Linda S., Tice, Hope, Ticknor, Lawrence O., Wills, Patti L., Gilna, Paul, and Brettin, Thomas S.

Subjects
Basic biological sciences
Abstract

Bacillus thuringiensis is an insect pathogen that is widely used as a biopesticide (3). Here we report the finished, annotated genome sequence of B. thuringiensis Al Hakam, which was collected in Iraq by the United Nations Special Commission (2).

Published
2008

2. The Pathogenomic Sequence Analysis of B. cereus and B. thuringiensis Isolates Closely Related to Bacillus anthracis

Author

Han, Cliff S., Xie, Gary, Challacombe, Jean F., Altherr, Michael R., Smriti, B., Bruce, David, Campbell, Connie S., Campbell, Mary L., Chen, Jin, Chertkov, Olga, Cleland, Cathy, Dimitrijevic-Bussod, M., Doggett, Norman A., Fawcett, John J., Glavina, Tijana, Goodwin, Lynne A., Hill, Karen K., Hitchcock, Penny, Jackson, Paul J., Keim, Paul, Kewalramani, Avinash Ramesh, Longmire, Jon, Lucas, Susan, Malfatti, Stephanie, McMurry, Kim, Meincke, Linda J., Misra, Monica, Moseman, Bernice L., Mundt, Mark, Munk, A. Christine, Okinaka, Richard T., Parson-Quintana, B., Reilly, Lee P., Richardson, Paul, Robinson, Donna L., Rubin, Eddy, Saunders, Elizabeth, Tapia, Roxanne, Tesmer, Judith G., Thayer, Nina, Thompson, Linda S., Tice, Hope, Ticknor, Lawrence O., Wills, Patti L., Gilna, Payl, and Brettin, Thomas S.

Subjects
Basic biological sciences, Comparative analysis genomics evolution virulence opportunistic pathogen
Abstract

The sequencing and analysis of two close relatives of Bacillus anthracis are reported. AFLP analysis of over 300 isolates of B. cereus, B. thuringiensis and B. anthracis identified two isolates as being very closely related to B. anthracis. One, a B. cereus, BcE33L, was isolated from a zebra carcass in Nambia; the second, a B. thuringiensis, 97-27, was isolated from a necrotic human wound. The B. cereus appears to be the closest anthracis relative sequenced to date. A core genome of over 3,900 genes was compiled for the Bacillus cereus group, including B anthracis. Comparative analysis of these two genomes with other members of the B. cereus group provides insight into the evolutionary relationships among these organisms. Evidence is presented that differential regulation modulates virulence, rather than simple acquisition of virulence factors. These genome sequences provide insight into the molecular mechanisms contributing to the host range and virulence of this group of organisms.

Published
2005

3. The sequence and analysis of duplication rich human chromosome 16

Author

Martin, Joel, Han, Cliff, Gordon, Laurie A., Terry, Astrid, Prabhakar, Shyam, She, Xinwei, Xie, Gary, Hellsten, Uffe, Man Chan, Yee, Altherr, Michael, Couronne, Olivier, Aerts, Andrea, Bajorek, Eva, Black, Stacey, Blumer, Heather, Branscomb, Elbert, Brown, Nancy C., Bruno, William J., Buckingham, Judith M., Callen, David F., Campbell, Connie S., Campbell, Mary L., Campbell, Evelyn W., Caoile, Chenier, Challacombe, Jean F., Chasteen, Leslie A., Chertkov, Olga, Chi, Han C., Christensen, Mari, Clark, Lynn M., Cohn, Judith D., Denys, Mirian, Detter, John C., Dickson, Mark, Dimitrijevic-Bussod, Mira, Escobar, Julio, Fawcett, Joseph J., Flowers, Dave, Fotopulos, Dea, Glavina, Tijana, Gomez, Maria, Gonzales, Eidelyn, Goodstein, David, Goodwin, Lynne A., Grady, Deborah L., Grigoriev, Igor, Groza, Matthew, Hammon, Nancy, Hawkins, Trevor, Haydu, Lauren, Hildebrand, Carl E., Huang, Wayne, Israni, Sanjay, Jett, Jamie, Jewett, Phillip E., Kadner, Kristen, Kimball, Heather, Kobayashi, Arthur, Krawczyk, Marie-Claude, Leyba, Tina, Longmire, Jonathan L., Lopez, Frederick, Lou, Yunian, Lowry, Steve, Ludeman, Thom, Mark, Graham A., Mcmurray, Kimberly L., Meincke, Linda J., Morgan, Jenna, Moyzis, Robert K., Mundt, Mark O., Munk, A. Christine, Nandkeshwar, Richard D., Pitluck, Sam, Pollard, Martin, Predki, Paul, Parson-Quintana, Beverly, Ramirez, Lucia, Rash, Sam, Retterer, James, Ricke, Darryl O., Robinson, Donna L., Rodriguez, Alex, Salamov, Asaf, Saunders, Elizabeth H., Scott, Duncan, Shough, Timothy, Stallings, Raymond L., Stalvey, Malinda, Sutherland, Robert D., Tapia, Roxanne, Tesmer, Judith G., Thayer, Nina, Thompson, Linda S., Tice, Hope, Torney, David C., Tran-Gyamfi, Mary, Tsai, Ming, Ulanovsky, Levy E., and Ustaszewska, Anna

Subjects
Applied life sciences
Abstract

We report here the 78,884,754 base pairs of finished human chromosome 16 sequence, representing over 99.9 percent of its euchromatin. Manual annotation revealed 880 protein coding genes confirmed by 1,637 aligned transcripts, 19 tRNA genes, 341 pseudogenes and 3 RNA pseudogenes. These genes include metallothionein, cadherin and iroquois gene families, as well as the disease genes for polycystic kidney disease and acute myelomonocytic leukemia. Several large-scale structural polymorphisms spanning hundreds of kilobasepairs were identified and result in gene content differences across humans. One of the unique features of chromosome 16 is its high level of segmental duplication, ranked among the highest of the human autosomes. While the segmental duplications are enriched in the relatively gene poor pericentromere of the p-arm, some are involved in recent gene duplication and conversion events which are likely to have had an impact on the evolution of primates and human disease susceptibility.

Published
2004

4. Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis

Author

Han, Cliff S., Xie, Gary, Challacombe, Jean F., Altherr, Michael R., Bhotika, Smriti S., Bruce, David, Campbell, Connie S., Campbell, Mary L., Chen, Jin, Chertkov, Olga, Cleland, Cathy, Dimitrijevic, Mira, Doggett, Norman A., Fawcett, John J., Glavina, Tijana, Goodwin, Lynne A., Hill, Karen K., Hitchcock, Penny, Jackson, Paul J., Keim, Paul, Kewalramani, Avinash Ramesh, Longmire, Jon, Lucas, Susan, Malfatti, Stephanie, McMurry, Kim, Meincke, Linda J., Misra, Monica, Moseman, Bernice L., Mundt, Mark, Munk, A. Christine, Okinaka, Richard T., Parson-Quintana, B., Reilly, Lee Philip, Richardson, Paul, Robinson, Donna L., Rubin, Eddy, Saunders, Elizabeth, Tapia, Roxanne, Tesmer, Judith G., Thayer, Nina, Thompson, Linda S., Tice, Hope, Ticknor, Lawrence O., Wills, Patti L., Brettin, Thomas S., and Gilna, Paul

Subjects
Bacillus cereus -- Environmental aspects, Bacillus cereus -- Genetic aspects, Bacillus thuringiensis -- Environmental aspects, Bacillus thuringiensis -- Genetic aspects, Bacillus anthracis -- Environmental aspects, Bacillus anthracis -- Genetic aspects, Genetic research, Biological sciences
Abstract

Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis are closely related gram-positive, spore-forming bacteria of the B. cereus sensu lato group. While independently derived strains of B. anthracis reveal conspicuous sequence homogeneity, environmental isolates of B. cereus and B. thuringiensis exhibit extensive genetic diversity. Here we report the sequencing and comparative analysis of the genomes of two members of the B. cereus group, B. thuringiensis 97-27 subsp, konkukian serotype H34, isolated from a necrotic human wound, and B. cereus E33L, which was isolated from a swab of a zebra carcass in Namibia. These two strains, when analyzed by amplified fragment length polymorphism within a collection of over 300 of B. cereus, B. thuringiensis, and B. anthracis isolates, appear closely related to B. anthracis. The B. cereus E33L isolate appears to be the nearest relative to B. anthracis identified thus far. Whole-genome sequencing of B. thuringiensis 97-27 and B. cereus E33L was undertaken to identify shared and unique genes among these isolates in comparison to the genomes of pathogenic strains B. anthracis Ames and B. cereus G9241 and nonpathogenic strains B. cereus ATCC 10987 and B. cereus ATCC 14579. Comparison of these genomes revealed differences in terms of virulence, metabolic competence, structural components, and regulatory mechanisms.

Published
2006

5. The complete genome sequence of Bacillus thuringiensis Al Hakam

Author

Challacombe, Jean F., Altherr, Michael R., Xie, Gary, Bhotika, Smriti S., Brown, Nancy, Bruce, David, Campbell, Connie S., Campbell, Mary L., Chen, Jin, Chertkov, Olga, Cleland, Cathy, Dimitrijevic, Mira, Doggett, Norman A., Fawcett, John J., Glavina, Tijana, Goodwin, Lynne A., Green, Lance D., Han, Cliff S., Hill, Karen K., Hitchcock, Penny, Jackson, Paul J., Keim, Paul, Kewalramani, Avinash Ramesh, Longmire, Jon, Lucas, Susan, Malfatti, Stephanie, Martinez, Diego, McMurry, Kim, Meincke, Linda J., Misra, Monica, Moseman, Bernice L., Mundt, Mark, Munk, A. Christine, Okinaka, Richard T., Parson-Quintana, B., Reilly, Lee Philip, Richardson, Paul, Robinson, Donna L., Saunders, Elizabeth, Tapia, Roxanne, Tesmer, Judith G., Thayer, Nina, Thompson, Linda S., Tice, Hope, Ticknor, Lawrence O., Wills, Patti L., Gilna, Paul, and Brettin, Thomas S.

Subjects
Bacillus thuringiensis -- Genetic aspects, Bacillus thuringiensis -- Research, Genomes -- Research, Biological sciences
Abstract

Bacillus thuringiensis is an insect pathogen that is widely used as a biopesticide (E. Schnepf, N. Crickmore, J. Van Rie, D. Lereclus, J. Baum, J. Feitelson, D. R. Zeigler, and D. H. Dean, Microbiol. Mol. Biol. Rev. 62:775-806, 1998). Here we report the finished, annotated genome sequence of B. thuringiensis Al Hakam, which was collected in Iraq by the United Nations Special Commission (L. Radnedge, P. Agron, K. Hill, P. Jackson, L. Ticknor, P. Keim, and G. Andersen, Appl. Environ. Microbiol. 69:2755-2764, 2003). doi:10.1128/JB.00241-07

Published
2007

6. The sequence and analysis of duplication-rich human chromosome 16

Author

Martin, Joel, primary, Han, Cliff, additional, Gordon, Laurie A., additional, Terry, Astrid, additional, Prabhakar, Shyam, additional, She, Xinwei, additional, Xie, Gary, additional, Hellsten, Uffe, additional, Chan, Yee Man, additional, Altherr, Michael, additional, Couronne, Olivier, additional, Aerts, Andrea, additional, Bajorek, Eva, additional, Black, Stacey, additional, Blumer, Heather, additional, Branscomb, Elbert, additional, Brown, Nancy C., additional, Bruno, William J., additional, Buckingham, Judith M., additional, Callen, David F., additional, Campbell, Connie S., additional, Campbell, Mary L., additional, Campbell, Evelyn W., additional, Caoile, Chenier, additional, Challacombe, Jean F., additional, Chasteen, Leslie A., additional, Chertkov, Olga, additional, Chi, Han C., additional, Christensen, Mari, additional, Clark, Lynn M., additional, Cohn, Judith D., additional, Denys, Mirian, additional, Detter, John C., additional, Dickson, Mark, additional, Dimitrijevic-Bussod, Mira, additional, Escobar, Julio, additional, Fawcett, Joseph J., additional, Flowers, Dave, additional, Fotopulos, Dea, additional, Glavina, Tijana, additional, Gomez, Maria, additional, Gonzales, Eidelyn, additional, Goodstein, David, additional, Goodwin, Lynne A., additional, Grady, Deborah L., additional, Grigoriev, Igor, additional, Groza, Matthew, additional, Hammon, Nancy, additional, Hawkins, Trevor, additional, Haydu, Lauren, additional, Hildebrand, Carl E., additional, Huang, Wayne, additional, Israni, Sanjay, additional, Jett, Jamie, additional, Jewett, Phillip B., additional, Kadner, Kristen, additional, Kimball, Heather, additional, Kobayashi, Arthur, additional, Krawczyk, Marie-Claude, additional, Leyba, Tina, additional, Longmire, Jonathan L., additional, Lopez, Frederick, additional, Lou, Yunian, additional, Lowry, Steve, additional, Ludeman, Thom, additional, Manohar, Chitra F., additional, Mark, Graham A., additional, McMurray, Kimberly L., additional, Meincke, Linda J., additional, Morgan, Jenna, additional, Moyzis, Robert K., additional, Mundt, Mark O., additional, Munk, A. Christine, additional, Nandkeshwar, Richard D., additional, Pitluck, Sam, additional, Pollard, Martin, additional, Predki, Paul, additional, Parson-Quintana, Beverly, additional, Ramirez, Lucia, additional, Rash, Sam, additional, Retterer, James, additional, Ricke, Darryl O., additional, Robinson, Donna L., additional, Rodriguez, Alex, additional, Salamov, Asaf, additional, Saunders, Elizabeth H., additional, Scott, Duncan, additional, Shough, Timothy, additional, Stallings, Raymond L., additional, Stalvey, Malinda, additional, Sutherland, Robert D., additional, Tapia, Roxanne, additional, Tesmer, Judith G., additional, Thayer, Nina, additional, Thompson, Linda S., additional, Tice, Hope, additional, Torney, David C., additional, Tran-Gyamfi, Mary, additional, Tsai, Ming, additional, Ulanovsky, Levy E., additional, Ustaszewska, Anna, additional, Vo, Nu, additional, Scott White, P., additional, Williams, Albert L., additional, Wills, Patricia L., additional, Wu, Jung-Rung, additional, Wu, Kevin, additional, Yang, Joan, additional, DeJong, Pieter, additional, Bruce, David, additional, Doggett, Norman A., additional, Deaven, Larry, additional, Schmutz, Jeremy, additional, Grimwood, Jane, additional, Richardson, Paul, additional, Rokhsar, Daniel S., additional, Eichler, Evan E., additional, Gilna, Paul, additional, Lucas, Susan M., additional, Myers, Richard M., additional, Rubin, Edward M., additional, and Pennacchio, Len A., additional

Published
2004
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