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Despite the advantages proffered by technology in science education, little has been done to develop and validate innovative technology-based instructional materials on Central Dogma of Molecular Biology. It is imperative to test any newly generated instructional materials to validate their quality before being widely used. Hence, this study aimed to validate the developed simulation-based instructional materials on Central Dogma of Molecular Biology for Senior High School. This study utilized Research and Development (R&D) design involving 50 Grade 12 STEM learners and 15 Biology education experts chosen through purposive sampling. Results revealed that experts strongly agreed that the developed simulation-based instructional materials on Central Dogma of Molecular Biology have content, technical, and instructional qualities. Meanwhile, the pretest and posttest results revealed that the learners demonstrated significant conceptual improvement from approaching proficiency to advanced mastery level in Central Dogma of Molecular Biology concepts. Further, the learners' pretest and posttest mean scores on the concepts differed significantly (p<0.05). Therefore, it is recommended that the developed simulation-based instructional materials be used to complement in teaching Central Dogma of Molecular Biology.

The essence of Genetics lies in the understanding of the concepts of Central Dogma of Molecular Biology. Although these ideas are fundamental to the field, they are notoriously difficult to understand and visualize. While simulation-based instructional materials are found to improve the teaching-learning process in science education, little has been done to assess their effectiveness in teaching and learning the concepts of Central Dogma of Molecular Biology. Hence, this study aimed to examine the effectiveness of simulation-based instructional materials towards the learning performance of Grade 12 learners on the concepts of Central Dogma of Molecular Biology. This study utilized a mixed-method approach. Results of the pretest and posttest showed that the learners demonstrated from approaching proficiency to advanced mastery level on the concepts of Central Dogma of Molecular Biology. Furthermore, it was revealed that the pretest and posttest mean scores of the learners on the concepts differed significantly (p<0.05). The result of the semi-structured interview revealed that the learners were engaged in experiential learning with the use of simulation-based instructional materials. An action plan was designed based on the study to utilize the simulation-based instructional materials in the teaching-learning process.

Due to the global health crisis, many people lost their jobs or had to accept lower compensation. To mitigate the economic constraints caused by the pandemic, people pursued entrepreneurship to help meet their basic needs. However, to become successful in the field of entrepreneurship, one must possess a high level of entrepreneurial attitude and intention. Although a considerable study had been conducted to assess the level of entrepreneurial attitude and intention, its Senior High School (SHS) level implementation had only received far less attention. Likewise, a dearth of literature assesses the level of entrepreneurial attitude and intention among Accountancy, Business and Management (ABM) SHS learners. Hence, this study was conducted to determine the level of entrepreneurial attitude and intentions of the Grade 12 ABM SHS learners. The study utilized a descriptive correlational research design. A total of 58 ABM SHS learners from NDMU-IBED, Philippines, were purposively chosen as the respondents of the study. Results revealed that the learners have a high entrepreneurial attitude and intention. Further, Spearman's correlation revealed that there was a statistically significant moderate positive correlation (p<0.05) between the two variables. These indicate that learners have a high attitude toward becoming an entrepreneur and desire to put up or start their businesses. More so, ABM SHS learners' entrepreneurial attitude can be used as a predictor of their entrepreneurial intention. [ABSTRACT FROM AUTHOR]