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Background: Leukemia is the most frequent cancer in children and adolescents, and it has a high prevalence of depression and anxiety which deteriorates the quality of life related to health. The symptoms of depression and anxiety may go unnoticed by the physician as a normal response during cancer treatment. Objective: To determine the prevalence of depression, anxiety and health-related quality of life in pediatric patients with leukemia. Material and methods: study with the participation of Mexican children and adolescents with leukemia whose depression was determined with the Childhood Depression Inventory, their anxiety with the Spence Childhood Anxiety Scale, and their health-related quality of life (HRQoL) with PedsQL 4.0. Results: 37 participants, with a median age of 11 years (8-14 years); 19 (51.4%) were male. The marital status of the parents in 25 participants (67.5%) was married, in 10 (27%) had a domestic partnership, in one (2.7%) had divorced parents and in one it was single (2.7%). The prevailing religion was Catholic in 29 (78.3%); 16 patients (43.2%) reported depression, 10% anxiety and 94.5% reported an adequate healthrelated quality of life, with an average of 74.2 ± 16.2. Conclusions: Depression was the most prevalent, followed by anxiety. Health-related quality of life was reported as good. The harmful impact is still prevalent in a vulnerable population, which must be attended in a comprehensive and timely manner at all levels of care. [ABSTRACT FROM AUTHOR]

Background: Leukemia is the most frequent cancer in children and adolescents, and it has a high prevalence of depression and anxiety which deteriorates the quality of life related to health. The symptoms of depression and anxiety may go unnoticed by the physician as a normal response during cancer treatment., Objective: To determine the prevalence of depression, anxiety and health-related quality of life in pediatric patients with leukemia., Material and Methods: study with the participation of Mexican children and adolescents with leukemia whose depression was determined with the Childhood Depression Inventory, their anxiety with the Spence Childhood Anxiety Scale, and their health-related quality of life (HRQoL) with PedsQL 4.0., Results: 37 participants, with a median age of 11 years (8-14 years); 19 (51.4%) were male. The marital status of the parents in 25 participants (67.5%) was married, in 10 (27%) had a domestic partnership, in one (2.7%) had divorced parents and in one it was single (2.7%). The prevailing religion was Catholic in 29 (78.3%); 16 patients (43.2%) reported depression, 10% anxiety and 94.5% reported an adequate health-related quality of life, with an average of 74.2 +- 16.2., Conclusions: Depression was the most prevalent, followed by anxiety. Health-related quality of life was reported as good. The harmful impact is still prevalent in a vulnerable population, which must be attended in a comprehensive and timely manner at all levels of care., (© 2022 Revista Médica del Instituto Mexicano del Seguro Social.)

Background: The cardiac troponin I (cTnI), creatine phospokinase (CPK), and creatine kinase- myocardial band (CK-MB) are cardiac biomarkers used in newborns with asphyxia., Objective: To analyze the relationship between cTnI, CPK and CPK-MB levels with clinical and biochemical diagnostic criteria for neonatal asphyxia., Methods: Analytical cross-sectional study in neonates with at least one diagnostic criterion of asphyxia. Relationship among cTnI and CPK-MB levels at birth, serum levels of CPK and CPK-MB determined 24 hours after delivery, with metabolic acidosis, Apgar test at 5 minutes with scores of 0-3, neurological alterations and/or multiple organ failure were analyzed., Results: Thirty-four neonates, 73.5% born by cesarean section, 71% term neonates with a mean weight of 3,096 ± 453g, 2,275 ± 509g for preterm, and a mean of 7.77 ± 1.481 and 7.03 ± 1.705 5-minute Apgar score, respectively. 17.6% of the neonates reported a pH value < 7.20, 58% a base deficit of 12 mmol/L, 5.8% obtained a 5-minute Apgar score < 3, and 38.23% had neurological alterations and/or multiple organ dysfunction syndrome. All patients reported cTnI within the normal reference range. CPK and CPK-MB values, 24 hours after delivery, were elevated in 29% of the cases with one or two diagnostic criteria for neonatal asphyxia. The percentage of CPK-MB was associated with gestational age., Conclusions: cTnI values were normal in suspected cases of neonatal asphyxia, whereas CPK and CPK MB can elevate in these population, principally in preterm newborns. Biochemical markers were not associated with any clinical parameter., (Copyright: © 2020 Revista Medica del Instituto Mexicano del Seguro Social.)

Breastfeeding is one of the oldest and most useful practices for human race. It is crucial for optimal newborn development and yet the stigma built around it has proven to be devastating for its implementation over the years. For the past few decades, numerous studies have been conducted to shed light on the countless benefits of breastfeeding and to cast off the taboo around it. In 1991 the World Health Organization, together with the United Nations International Children's Emergency Fund, created the Baby-Friendly Hospital Initiative (BFHI) with the aim of protecting, promoting and strengthening breastfeeding in hospitals and health centers, through the implementation of 10 steps to successful breastfeeding . There are a number of requirements that must be fulfilled in order to implement this initiative. However, due to local and regional characteristics of each health care unit, a certain degree of adequacy of these steps is required for its implementation. Therefore, at the Instituto Mexicano del Seguro Social (Mexican Institute for Social Security), seven steps and three annexes have been adapted for their implementation in the first level health care units of this institution.