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This document discusses two separate research studies. The first study focuses on innovative approaches in molecular diagnostics, specifically the use of bead-based platforms for liquid biopsy nucleic acid detection. The researchers aim to develop biosensors that can monitor the behavior and regulation of protein kinases in real-time, providing new tools for studying immune function. The second study explores the potential use of cacao as a treatment for cognitive impairments induced by cocaine. The researchers propose that a diet enriched with cacao, which is rich in polyphenols, could improve brain plasticity and cognitive function. Both studies offer valuable insights into their respective fields of research. [Extracted from the article]

Adipose-derived stem cells (ASCs) are multipotent cells that are emerging as an extremely promising therapeutic agent for tissue regeneration. The ability to manipulate ASC phenotypes by the delivery of biologically active cargoes is essential to understand their role and to design novel therapeutic strategies based on the use of ASCs. Here we describe a simple and efficient protocol for the conjugation and efficient delivery of biological materials into ASCs based on the use of polystyrene nanoparticles as carrier system.