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1. Anterior and Lateral Lumbar Interbody Fusion With Supplemental Interspinous Process Fixation: Outcomes from a Multicenter, Prospective, Randomized, Controlled Study.

Author

Panchal, Ripul, Denhaese, Ryan, Hill, Clint, Strenge, K Brandon, DE Moura, Alexandre, Passias, Peter, Arnold, Paul, Cappuccino, Andrew, Dennis, M David, Kranenburg, Andy, Ventimiglia, Brieta, Martin, Kim, Ferry, Chris, Martineck, Sarah, Moore, Camille, and Kim, Kee

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Clinical Trials and Supportive Activities, Good Health and Well Being, interspinous process fixation, ISPF, lateral lumbar interbody fusion, LLIF, anterior lumbar interbody fusion, ALIF, degenerative disc disease, lumbar spine, posterior fixation, minimally invasive, MIS, spondylolisthesis, Neurosciences, Clinical sciences
Abstract

BackgroundRigid interspinous process fixation (ISPF) has received consideration as an efficient, minimally disruptive technique in supporting lumbar interbody fusion. However, despite advantageous intraoperative utility, limited evidence exists characterizing midterm to long-term clinical outcomes with ISPF. The objective of this multicenter study was to prospectively assess patients receiving single-level anterior (ALIF) or lateral (LLIF) lumbar interbody fusion with adjunctive ISPF.MethodsThis was a prospective, randomized, multicenter (11 investigators), noninferiority trial. All patients received single-level ALIF or LLIF with supplemental ISPF (n = 66) or pedicle screw fixation (PSF; n = 37) for degenerative disc disease and/or spondylolisthesis (grade ≤2). The randomization patient ratio was 2:1, ISPF/PSF. Perioperative and follow-up outcomes were collected (6 weeks, 3 months, 6 months, and 12 months).ResultsFor ISPF patients, mean posterior intraoperative outcomes were: blood loss, 70.9 mL; operating time, 52.2 minutes; incision length, 5.5 cm; and fluoroscopic imaging time, 10.4 seconds. Statistically significant improvement in patient Oswestry Disability Index scores were achieved by just 6 weeks after operation (P

Published
2018

2. Prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of lumbar total disc replacement with the CHARITÉ artificial disc versus lumbar fusion: Five-year follow-up

Author

Guyer, Richard D., McAfee, Paul C., Banco, Robert J., Bitan, Fabian D., Cappuccino, Andrew, Geisler, Fred H., Hochschuler, Stephen H., Holt, Richard T., Jenis, Louis G., Majd, Mohamed E., Regan, John J., Tromanhauser, Scott G., Wong, Douglas C., and Blumenthal, Scott L.

Published
2009
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3. Cervical Disc Replacement Revisions

Author

Pimenta, Luiz, primary, Díaz, Roberto, additional, McAfee, Paul C., additional, Cappuccino, Andrew G., additional, Cunningham, Bryan W., additional, Nicola, Hazem, additional, Lhamby, Juliano, additional, and Gharzeddine, Ihab, additional

Published
2008
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4. Contributors

Author

Abitbol, Jean-Jacques, primary, Ahrens, Michael, additional, Alamin, Todd F., additional, Albert, Todd J., additional, Allain, Jérome, additional, Ameil, Marc, additional, An, Howard S., additional, Ananthan, Ravi, additional, Anderson, Paul A., additional, Andrew, S.A., additional, Aubourg, Lucie, additional, Aunoble, Stephane, additional, Ball, Jonathon R., additional, Bao, Qi-Bin, additional, Beaurain, Jacques, additional, Bérard, Marco, additional, Berelmann, Ulrich, additional, Bernard, Pierre, additional, Bertagnoli, Rudolf, additional, Biscup, Robert S., additional, Blain, Jason D., additional, Block, Jon E., additional, Blumenthal, Scott L., additional, Boeree, Nicholas R., additional, Bogorin, Iohan, additional, Bradford, David S., additional, Buchowski, Jacob M., additional, Büttner-Janz, Karin, additional, Cappuccino, Andrew G., additional, Carl, Allen, additional, Castellvi, Antonio E., additional, Cauthen, Joseph C., additional, Chataigner, Hervé, additional, Cheng, Boyle C., additional, Chomiak, Robert J., additional, Coillard, Christine, additional, Cole, Christopher, additional, Colleran, Dennis, additional, Coric, Domagoj, additional, Bryan Cornwall, G., additional, Coutinho, Etevaldo, additional, Cragg, Andrew H., additional, Cunningham, Bryan W., additional, Cutter, David, additional, Daday, Frank, additional, Davis, Reginald J., additional, Delamarter, Rick B., additional, Delécrin, Joël, additional, DeVilliers, Malan, additional, Díaz, Roberto, additional, Dipp, Juan M., additional, Dix, Gary A., additional, Ducker, Thomas B., additional, Dufour, Thierry, additional, Einhorn, Jacob, additional, Eisermann, Lukas, additional, Errico, Thomas J., additional, Fagerstrom, Teddy, additional, Fassett, Daniel R., additional, Fischgrund, Jeffrey S., additional, Flores, Ricardo, additional, Fuentes, Jean-Marc, additional, Gabriel, Josue, additional, García, Rolando, additional, Geisler, Fred H., additional, Gharzeddine, Ihab, additional, Goel, Vijay K., additional, Goldstein, Jeffrey A., additional, Gornet, Matthew F., additional, Griffith, Steven L., additional, Guilhaume, Geneste, additional, Guizzardi, Giancarlo, additional, Guyer, Richard D., additional, Habela, Nader M., additional, Reinhard Hähnle, Ulrich, additional, Hale, Horace, additional, James Hallab, Nadim, additional, Hannallah, David, additional, Hannibal, Matthew, additional, Hayes, Victor M., additional, Hilibrand, Alan S., additional, Hipp, John A., additional, Hochschuler, Stephen H., additional, Holen, Gordon Neil, additional, Hovorka, Istvan, additional, Hoy, Robert W., additional, Hsu, Kenneth Y., additional, Huppert, Jean, additional, Idler, Cary, additional, Jackowski, Andre, additional, Jacobs, Joshua J., additional, Jaramillo, Jorge, additional, Jeyamohan, Shiveindra B., additional, Kang, James D., additional, Khoo, Larry T., additional, Woo Kim, Seok, additional, Kitchel, Scott H., additional, Knapik, Gregory G., additional, Krishna, Manoj, additional, Lambrecht, Greg, additional, Lauryssen, Carl, additional, Lavelle, William, additional, Lawrence, James P., additional, Le Huec, Jean-Charles, additional, Lhamby, Juliano, additional, Lowery, Gary L., additional, Malcolmon, George, additional, Marnay, Thierry, additional, Marras, William S., additional, Martin, Larry, additional, Marzluff, Joseph M., additional, Masuda, Koichi, additional, McAfee, Paul C., additional, McConnell, Jeffrey R., additional, McKenzie, Alvin H., additional, McLeod, Alan, additional, Metz, Lionel N., additional, Meyrat, Richard Blondet, additional, Miller, Scott Dean, additional, Mochida, Joji, additional, Navarro, Richard, additional, Nicola, Hazem, additional, Oberer, Daniel M., additional, Ohnmeiss, Donna D., additional, Oliveira, Carlos E., additional, Orndorff, Douglas G., additional, Osborn, Brett A., additional, Pacek, Corey A., additional, Park, Charles, additional, Patwardhan, Avinash G., additional, Fernando Arias Pesántez, Carlos, additional, Petrini, Piero, additional, Pimenta, Luiz, additional, Podichetty, Vinod K., additional, Poelstra, Kornelis A., additional, Pradhan, Ben B., additional, Prewett, Ann, additional, Price, James P., additional, Robert Rappaport, James, additional, Reah, Christopher, additional, Reyes-Sánchez, Alejandro A., additional, Rhalmi, Souad, additional, Daniel Riew, K., additional, Rivard, Charles H., additional, Rodríguez, German, additional, Roush, Thomas F., additional, Rushton, Scott A., additional, Sahai, Ashish, additional, Saiedy, Samer, additional, Sakai, Daisuke, additional, Sasso, Rick, additional, Schaffa, Thomas, additional, Schwarzenbach, Othmar, additional, Scott-Young, Matthew, additional, Sekhon, Lali H.S., additional, Sengupta, Dilip K., additional, Sethi, Rajiv K., additional, Siddiqi, Farhan N., additional, Singh, Kern, additional, Songer, Matthew N., additional, Sowa, Gwendolyn A., additional, Spate, Kristina, additional, Stecken, Jean, additional, Steib, Jean-Paul, additional, Steiber, Jonathan R., additional, Sullivan, Brian J., additional, Sumpio, Bauer E., additional, Teng, Andelle L., additional, Theken, Randall, additional, Peter Timm, Jens, additional, Tortolani, P. Justin, additional, Traynelis, Vincent C., additional, Tropiano, Patrick, additional, Tsantrizos, Anthony, additional, Turner, Alexander W.L., additional, Vaccaro, Alexander R., additional, Vital, Jean-Marc, additional, von Strempel, Archibald, additional, Wallach, Corey J., additional, Wang, Jeffrey C., additional, Wardlaw, Douglas, additional, Webb, Scott A., additional, Weinberg, Ian R., additional, Welch, William C., additional, Wessman, Bradley J., additional, Whang, Peter G., additional, Wharton, Nicholas D., additional, White, Andrew P., additional, Wilson, Thomas, additional, Wimmer, Markus, additional, Yeh, Oscar, additional, Yeung, Anthony T., additional, Yeung, Christopher A., additional, Yuan, Hansen A., additional, Yue, James J., additional, and Zucherman, James F., additional

Published
2008
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7. A Prospective, Randomized, Controlled Clinical Investigation Comparing PCM Cervical Disc Arthroplasty With Anterior Cervical Discectomy and Fusion

Author

Phillips, Frank M., primary, Lee, Joe Y. B., additional, Geisler, Fred H., additional, Cappuccino, Andrew, additional, Chaput, Christopher D., additional, DeVine, John G., additional, Reah, Christopher, additional, Gilder, Kye M., additional, Howell, Kelli M., additional, and McAfee, Paul C., additional

Published
2013
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10. Minimally Invasive Spine Surgery

Author

McAfee, Paul C., primary, Phillips, Frank M., additional, Andersson, Gunnar, additional, Buvenenadran, Asokumar, additional, Kim, Choll W., additional, Lauryssen, Carl, additional, Isaacs, Robert E., additional, Youssef, Jim A., additional, Brodke, Darrel S., additional, Cappuccino, Andrew, additional, Akbarnia, Behrooz A., additional, Mundis, Gregory M., additional, Smith, William D., additional, Uribe, Juan S., additional, Garfin, Steve, additional, Allen, R. Todd, additional, Rodgers, William Blake, additional, Pimenta, Luiz, additional, and Taylor, William, additional

Published
2010
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12. Radiographic Comparison of Two Lumbar Total Disc Replacement Devices: Results from a Prospective, Randomized, Controlled Multicenter FDA-Regulated Trial

Author

Guyer, Richard D., primary, Pettine, Kenneth A., additional, Knight, Reginald Q., additional, Dimmig, Thomas A., additional, Coric, Dom, additional, McAfee, Paul C., additional, Gordon, Charley, additional, Cappuccino, Andrew, additional, Buckley, Rudolph, additional, Nunley, Pierce, additional, Geisler, Fred, additional, Peppers, Timothy A., additional, Rappaport, James, additional, Dix, Gary, additional, Cheng, Wayne K., additional, Hu, Serena, additional, Lee, Yu-Po, additional, Bitan, Fabien D., additional, and Bains, Ravinder, additional

Published
2010
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13. Letters

Author

Cappuccino, Andrew, primary, Bisson, Leslie J., additional, Carpenter, Bud, additional, Dietrich, W. Dalton, additional, and Cappuccino, Helen, additional

Published
2010
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14. Direct Comparison of Two Lumbar Total Disc Replacement Devices: Results from a Prospective, Randomized, Multicenter FDA-Regulated Trial

Author

Guyer, Richard D., primary, Pettine, Kenneth A., additional, Knight, Reginald Q., additional, Dimmig, Thomas A., additional, Coric, Dom, additional, McAfee, Paul C., additional, Gordon, Charley, additional, Cappuccino, Andrew, additional, Buckley, Rudolph, additional, Nunley, Pierce, additional, Geisler, Fred, additional, Peppers, Timothy A., additional, Rappaport, James, additional, Dix, Gary, additional, Cheng, Wayne K., additional, Hu, Serena, additional, Lee, Yu-Po, additional, Bitan, Fabien D., additional, and Bains, Ravinder, additional

Published
2010
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22. Distribution of in vivo and in vitro range of motion following 1-level arthroplasty with the CHARITÉ artificial disc compared with fusion

Author

Cunningham, Bryan W., primary, McAfee, Paul C., additional, Geisler, Fred H., additional, Holsapple, Gwen, additional, Adams, Karen, additional, Blumenthal, Scott L., additional, Guyer, Richard D., additional, Cappuccino, Andrew, additional, Regan, John J., additional, Fedder, Ira L., additional, and Tortolani, P. Justin, additional

Published
2008
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37. VideoAssisted Thoracoscopic Surgery VersusOpen Thoracotomy for Anterior Thoracic Spinal Fusion

Author

Cunningham, Bryan W., Kotani, Yoshihisa, McNulty, Patrick S., Cappuccino, Andrew, Kanayama, Masahiro, Fedder, Ira L., and McAfee, Paul C.

Abstract

In this in vivoinvestigation, a sheep model was used to compare the efficacy of a videoassisted thoracoscopic approach and a traditional thoracotomy in promoting a successful interbody spinal arthrodesis.

Published
1998

40. Letters.

Author

Beauchamp, Kathryn M., Flierl, Michael A., Stahel, Philip F., Cappuccino, Andrew, and Bisson, Leslie J.

Published
2010
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42. Contributors

Author

Abitbol, Jean-Jacques, Ahrens, Michael, Alamin, Todd F., Albert, Todd J., Allain, Jérome, Ameil, Marc, An, Howard S., Ananthan, Ravi, Anderson, Paul A., Andrew, S.A., Aubourg, Lucie, Aunoble, Stephane, Ball, Jonathon R., Bao, Qi-Bin, Beaurain, Jacques, Bérard, Marco, Berelmann, Ulrich, Bernard, Pierre, Bertagnoli, Rudolf, Biscup, Robert S., Blain, Jason D., Block, Jon E., Blumenthal, Scott L., Boeree, Nicholas R., Bogorin, Iohan, Bradford, David S., Buchowski, Jacob M., Büttner-Janz, Karin, Cappuccino, Andrew G., Carl, Allen, Castellvi, Antonio E., Cauthen, Joseph C., Chataigner, Hervé, Cheng, Boyle C., Chomiak, Robert J., Coillard, Christine, Cole, Christopher, Colleran, Dennis, Coric, Domagoj, Bryan Cornwall, G., Coutinho, Etevaldo, Cragg, Andrew H., Cunningham, Bryan W., Cutter, David, Daday, Frank, Davis, Reginald J., Delamarter, Rick B., Delécrin, Joël, DeVilliers, Malan, Díaz, Roberto, Dipp, Juan M., Dix, Gary A., Ducker, Thomas B., Dufour, Thierry, Einhorn, Jacob, Eisermann, Lukas, Errico, Thomas J., Fagerstrom, Teddy, Fassett, Daniel R., Fischgrund, Jeffrey S., Flores, Ricardo, Fuentes, Jean-Marc, Gabriel, Josue, García, Rolando, Geisler, Fred H., Gharzeddine, Ihab, Goel, Vijay K., Goldstein, Jeffrey A., Gornet, Matthew F., Griffith, Steven L., Guilhaume, Geneste, Guizzardi, Giancarlo, Guyer, Richard D., Habela, Nader M., Reinhard Hähnle, Ulrich, Hale, Horace, James Hallab, Nadim, Hannallah, David, Hannibal, Matthew, Hayes, Victor M., Hilibrand, Alan S., Hipp, John A., Hochschuler, Stephen H., Holen, Gordon Neil, Hovorka, Istvan, Hoy, Robert W., Hsu, Kenneth Y., Huppert, Jean, Idler, Cary, Jackowski, Andre, Jacobs, Joshua J., Jaramillo, Jorge, Jeyamohan, Shiveindra B., Kang, James D., Khoo, Larry T., Woo Kim, Seok, Kitchel, Scott H., Knapik, Gregory G., Krishna, Manoj, Lambrecht, Greg, Lauryssen, Carl, Lavelle, William, Lawrence, James P., Le Huec, Jean-Charles, Lhamby, Juliano, Lowery, Gary L., Malcolmon, George, Marnay, Thierry, Marras, William S., Martin, Larry, Jr., Marzluff, Joseph M., Masuda, Koichi, McAfee, Paul C., McConnell, Jeffrey R., McKenzie, Alvin H., McLeod, Alan, Metz, Lionel N., Meyrat, Richard Blondet, Miller, Scott Dean, Mochida, Joji, Navarro, Richard, Nicola, Hazem, Oberer, Daniel M., Ohnmeiss, Donna D., Oliveira, Carlos E., Orndorff, Douglas G., Osborn, Brett A., Pacek, Corey A., Park, Charles, Patwardhan, Avinash G., Fernando Arias Pesántez, Carlos, Petrini, Piero, Pimenta, Luiz, Podichetty, Vinod K., Poelstra, Kornelis A., Pradhan, Ben B., Prewett, Ann, Price, James P., Robert Rappaport, James, Reah, Christopher, Reyes-Sánchez, Alejandro A., Rhalmi, Souad, Daniel Riew, K., Rivard, Charles H., Rodríguez, German, Roush, Thomas F., Rushton, Scott A., Sahai, Ashish, Saiedy, Samer, Sakai, Daisuke, Sasso, Rick, Schaffa, Thomas, Schwarzenbach, Othmar, Scott-Young, Matthew, Sekhon, Lali H.S., Sengupta, Dilip K., Sethi, Rajiv K., Siddiqi, Farhan N., Singh, Kern, Songer, Matthew N., Sowa, Gwendolyn A., Spate, Kristina, Stecken, Jean, Steib, Jean-Paul, Steiber, Jonathan R., Sullivan, Brian J., Sumpio, Bauer E., Teng, Andelle L., Theken, Randall, Peter Timm, Jens, Tortolani, P. Justin, Traynelis, Vincent C., Tropiano, Patrick, Tsantrizos, Anthony, Turner, Alexander W.L., Vaccaro, Alexander R., Vital, Jean-Marc, von Strempel, Archibald, Wallach, Corey J., Wang, Jeffrey C., Wardlaw, Douglas, Webb, Scott A., Weinberg, Ian R., Welch, William C., Wessman, Bradley J., Whang, Peter G., Wharton, Nicholas D., White, Andrew P., Wilson, Thomas, Wimmer, Markus, Yeh, Oscar, Yeung, Anthony T., Yeung, Christopher A., Yuan, Hansen A., Yue, James J., and Zucherman, James F.

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43. Systemic Hypothermia as Treatment for an Acute Cervical Spinal Cord Injury in a Professional Football Player: 9-Year Follow-Up.

Author

Cappuccino A, Bisson LJ, Carpenter B, Snyder K, and Cappuccino H

Subjects
Adult, Cervical Vertebrae diagnostic imaging, Combined Modality Therapy, Diskectomy, Humans, Laminectomy, Male, Spinal Fractures diagnostic imaging, Spinal Fusion methods, Cervical Vertebrae injuries, Football injuries, Hypothermia, Induced, Spinal Cord Injuries diagnostic imaging, Spinal Cord Injuries therapy, Spinal Fractures therapy
Abstract

The following report provides clinical follow-up on a National Football League player who sustained a complete cervical spinal cord injury (SCI) while tackling an opposing player in 2007. He received prompt medical and surgical care based on then-current recommendations, but was also treated with systemic hypothermia soon after his injury, which was controversial at the time. Since then, smaller randomized human studies have described the tolerable safety profile, efficacy, and potential benefits of this intervention in acute SCI in humans. Now, modest systemic hypothermia can be one of many tools considered in the treatment of acute SCI. Before it can become the standard of care, however, additional larger prospective randomized studies need to be completed. The patient described in this article had long-term excellent clinical results, with residual deficits of occasional tingling in fingertips and toe tips, although the patient continues to slowly improve., Competing Interests: Authors’ Disclosure Statement: The authors report no actual or potential conflict of interest in relation to this article.

Published
2017

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