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Resume Introduction L’impact de l’utilisation des colles biologiques et synthetiques en chirurgie cardiaque a ete evalue par une etude medicoeconomique. Materiel et methodes Une etude prospective observationnelle a ete realisee sur trois mois. Tous les patients operes ont ete inclus. Les criteres de jugement ont ete medicaux (transfusions de culots globulaires) et economiques (duree et cout de sejour). L’analyse statistique a porte sur deux groupes, traites ou non par de la colle. La comparaison des differents parametres a ete realisee par des tests de Student. Resultats Parmi les 154 patients, les deux principales indications etaient le remplacement valvulaire (48 %) et le pontage aorto-coronarien (37 %). Cinquante-sept (37 %) patients ont ete traites parmi lesquels le nombre de culots globulaires transfuses et la duree de sejour en reanimation ont ete statistiquement superieurs (p Conclusion L’utilisation des colles n’a pas diminue les saignements post-operatoires mais a augmente le cout de sejour. Des recommandations de bon usage ont ete validees par la commission du medicament et des dispositifs medicaux steriles (COMEDIMS).

The impact of the use of biological and synthetic glues in cardiac surgery was assessed by an economic and medical study.The observational prospective study had duration of three months. All the patients undergoing cardiac surgery were included in the study. The end points were medical (blood transfusion) and economic (duration and cost of the stay in hospital). There were 2 groups: treated or not by glues.T Student tests.Among 154 patients, the 2 principal indications were valvular replacement (48%) and coronary artery bypass grafting (37%). Fifty seven (37%) patients received a glue. The number of transfused globular units and the duration of the stay in the intensive care unit were significantly higher (p0.05) by treated patients.Not only the use of glues did not decrease the post-operative bleedings but it increased also the cost of the stay in hospital. Guidelines were validated by the hospital Commission on drugs.