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Your search keyword '"Caputo, Aurélia"' showing total 16 results
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16 results on '"Caputo, Aurélia"'

5. Genomic description and prevalence of two new Candidatus Saccharibacteria species from the human gut in different samples and countries

Author

Naud, Sabrina, primary, Caputo, Aurélia, additional, Anani, Hussein, additional, Ibrahim, Ahmad, additional, Levasseur, Anthony, additional, Million, Matthieu, additional, Bedotto, Marielle, additional, Diakite, Ami, additional, Dhiver, Catherine, additional, Dubourg, Grégory, additional, and Raoult, Didier, additional

Published
2022
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6. Epidemiology and genomic characterisation of travel-associated and locally-acquired influenza, Marseille, France

Author

Dao, Thi Loi, primary, Levasseur, Anthony, additional, Tall, Mamadou Lamine, additional, Hoang, Van Thuan, additional, Colson, Philippe, additional, Caputo, Aurélia, additional, Ly, Tran Duc Anh, additional, Ninove, Laetitia, additional, Grimaldier, Clio, additional, Jardot, Priscilla, additional, Marty, Pierre, additional, La Scola, Bernard, additional, and Gautret, Philippe, additional

Published
2022
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8. Deciphering the Urinary Microbiota Repertoire by Culturomics Reveals Mostly Anaerobic Bacteria From the Gut

Author

Dubourg, Grégory, primary, Morand, Aurélie, additional, Mekhalif, Fatima, additional, Godefroy, Raphael, additional, Corthier, Alice, additional, Yacouba, Abdourahamane, additional, Diakite, Ami, additional, Cornu, Florent, additional, Cresci, Marina, additional, Brahimi, Samy, additional, Caputo, Aurélia, additional, Lechevallier, Eric, additional, Tsimaratos, Michel, additional, Moal, Valérie, additional, Lagier, Jean-Christophe, additional, and Raoult, Didier, additional

Published
2020
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9. Phoenicibacter congonensis gen. nov., sp. nov., a new genus isolated from the human gut and its description using a taxonogenomic approach

Author

Bilen, Melhem, primary, Fonkou, Maxime Descartes Mbogning, additional, Caputo, Aurélia, additional, Nguyen, Thi-Thien, additional, Di Pinto, Fabrizio, additional, Bittar, Fadi, additional, Daoud, Ziad, additional, Levasseur, Anthony, additional, Fournier, Pierre Edouard, additional, Raoult, Didier, additional, and Cadoret, Frédéric, additional

Published
2018
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11. Whole-genome assembly of Akkermansia muciniphila sequenced directly from human stool

Author

Caputo, Aurélia, Dubourg, Grégory, Croce, Olivier, Gupta, Sushim, Robert, Catherine, Papazian, Laurent, Rolain, Jean-Marc, Raoult, Didier, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Hôpital de la Timone [CHU - APHM] (TIMONE), Service de Réanimation Médicale-Détresse Respiratoires et Infections Sévères, HAL AMU, Administrateur, and INSB-INSB-Centre National de la Recherche Scientifique (CNRS)

Subjects
DNA, Bacterial, Male, GENES, Gut microbiota, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Feces, Verrucomicrobia, Antibiotics, INTESTINAL MICROBIOTA, Cluster Analysis, Humans, TOOL, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, BACTERIAL GENOMES, SERVER, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Genome, Agricultural and Biological Sciences(all), Base Sequence, FLORA, Biochemistry, Genetics and Molecular Biology(all), Research, Microbiota, Chromosome Mapping, Middle Aged, Anti-Bacterial Agents, Intestines, HUMAN GUT MICROBIOTA, OBESITY, Metagenome, SP-NOV, RNA, Metagenomics, Enterococcus, Genome, Bacterial, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Akkermansia muciniphila
Abstract

Background Alterations in gut microbiota composition under antibiotic pressure have been widely studied, revealing a restricted diversity of gut flora, including colonization by organisms such as Enterococci, while their impact on bacterial load is variable. High-level colonization by Akkermansia muciniphila, ranging from 39% to 84% of the total bacterial population, has been recently reported in two patients being treated with broad-spectrum antibiotics, although attempts to cultivate this microorganism have been unsuccessful. Results Here, we propose an original approach of genome sequencing for Akkermansia muciniphila directly from the stool sample collected from one of these patients. We performed and assembly using metagenomic data obtained from the stool sample. We used a mapping method consisting of aligning metagenomic sequencing reads against the reference genome of the Akkermansia muciniphila MucT strain, and a De novo assembly to support this mapping method. We obtained draft genome of the Akkermansia muciniphila strain Urmite with only 56 gaps. The absence of particular metabolic requirement as possible explanation of our inability to culture this microorganism, suggests that the bacterium was dead before the inoculation of the stool sample. Additional antibiotic resistance genes were found following comparison with the reference genome, providing some clues pertaining to its survival and colonization in the gut of a patient treated with broad-spectrum antimicrobial agents. However, no gene coding for imipenem resistance was detected, although this antibiotic was a part of the patient’s antibiotic regimen. Conclusions This work highlights the potential of metagenomics to facilitate the assembly of genomes directly from human stool. Reviewers This article was reviewed by Eric Bapteste, William Martin and Vivek Anantharaman. Electronic supplementary material The online version of this article (doi:10.1186/s13062-015-0041-1) contains supplementary material, which is available to authorized users.

Published
2015

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