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1,087 results on '"Caputo, G."'

9. Why are so huge differences reported in the occurrence rate of skin lipohypertrophy? Does it depend on method defects or on lack of interest?

Author

Brancario, C., Corigliano, M., Cozzolino, G., Improta, M.R., Fasolino, A., Lamberti, C., Lapice, M., Martino, C., Oliva, D., Raffaele, A., Selleri, A., Simonetti, R., Stile, A., Vecchiato, A., Vetrano, A., Volpe, P., Caputo, G., Del Sorbo, A., Di Capua, M.G., Durazzo, G., Egidio, M., Garofalo, G., Grasso, L., Meo, A., Murano, A., Perillo, L., Procida, R., Vietsi, F., Gentile, S., Strollo, F., and Guarino, G.

Published
2019
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16. Civil Wastewater Remediation through Employment of Indigenous Microalgae and Sewage Sludge

Author

Lima S., D'Agostino N., Brucato A., Caputo G., Grisafi F., Scargiali F., Lima S., D'Agostino N., Brucato A., Caputo G., Grisafi F., and Scargiali F.

Subjects
Settore ING-IND/25 - Impianti Chimici, bioreactors, wastewater, MICROALGAE
Abstract

Microalgae are photosynthetic microorganisms that can employ some inorganic pollutant compounds as nutrients, for example nitrates and phosphates. Traditional wastewater treatment comprises oxidation ponds in which the Activated Sludge performs the oxidation of the organic matter. Microalgae may be well applied in these processes. In this work, we tested the potential of remediation of a mixture of a local microalga, Chlorella sp. Pozzillo, and activated sludge and compared it to controls of only microalga and only activated sludge. We found that the mixture of bacteria and microalgae leads to an improvement in nitrogen removal up to the 83,68%, while phosphorous removal is improved when the autochthonous microalgae are used alone. The abatement of the Chemical Oxygen Demand was of 59,17% when using the microalgae and activated sludge consortium, while it was higher (-76,67%±0) when using the only activated sludge. The biomass was also analysed for its content in lipids and carbohydrates. This information may be useful to assess the best industrial application for the biomass obtained from civil wastewaters remediation process, in accordance with principles of circular economy and waste-to-resources view.

Published
2022

18. Thermocline Thermal Storage for Concentrated Solar Power Applications: Characterization of Novel Nitrate Salt Mixtures

Author

Canneto, G., Tizzoni, A. C., Sau, S., Mansi, E., Gaggioli, W., Spadoni, A., Corsaro, N., Capocelli, M., Caputo, G., Galindo, F., and Della Libera, A.

Subjects
Renewable Energy, Sustainability and the Environment, Energy Engineering and Power Technology
Abstract

Parabolic trough concentrated solar power (CSP) plants are particularly promising renewable sources of energy, whose easy integration with thermal energy storage (TES) systems allows to mitigate the intermittency of electricity generation. Currently, molten nitrates, with two tanks arrangement, are mainly used for sensible heat accumulation. To reduce costs and make the CSP storage systems more manageable, single tank configurations have been proposed, where the cold and hot fluids are stored in the same container and separated because of their density difference. The aim of the present work is to study the storage performances presented by two novel ternary and quaternary mixtures, proposed within the European project IN POWER. An experimental campaign was preliminarily performed to investigate the fluids thermo-physical properties, and the obtained values were utilized as input data to model the discharge phase in a thermocline tank. The simulation results were compared with the ones acquired considering two commercial materials, namely, solar salt and Hitec XL®. Overall, considering same temperature ranges, higher discharging times are obtained for the quaternary and ternary mixtures, with the ternary presenting a smaller thermocline thickness than the solar salt while this parameter is the same considering the quaternary and Hitec XL®.

Published
2022
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19. Sociologie et littérature face à la question du travail: le cas italien

Author

Orientale Caputo G., Lazzarin S., Orientale Caputo, G., and Lazzarin, S.

Subjects
sociologie, littérature, usage sociologique des sources littéraires, représentation littéraire du travail, précarité, marché du travail en Italie sociology, literature, sociological approach to literary texts, literary representation of employment and labour market, temporary employments, labor market in Italy
Abstract

Cette étude se propose de réfléchir sur le rapport entre sociologie et littérature, en revenant sur la question cruciale – et toujours ouverte – de la légitimité de l’usage sociologique des sources littéraires. Il s’agira notamment ici d’enquêter sur une articulation particulière de cette relation, le récit littéraire du monde du travail, en examinant plus spécifiquement le cas italien. À l’instar d’autres pays occidentaux – mais peut-être plus qu’eux – l’Italie a expérimenté les transformations récentes du monde du travail (flexibilité, précarisation, parcellisation), et elle a produit, ces vingt dernières années, une grande quantité de textes littéraires qui mettent en scène de tels changements en tâchant de les interpréter. This essay aims to reflect upon the relationship between sociology and literature as well as upon the crucial issue – on which scholars haven’t yet agreed – of whether literary sources can be interpreted using a sociological approach. In particular, this will involve addressing literary renderings of employment, labour market, and working life, looking more specifically at the Italian case. Like other western countries – but perhaps to an even larger extent – Italy has recently experienced significant transformations in the labour market and its employment conditions (workplace flexibility, temporary employments, fragmentation of the labour force) and has produced a large number of literary texts that address these transformations and attempt to interpret them.

Published
2022

20. Visual perception and dissociation during Mirror Gazing Test in patients with anorexia nervosa: a preliminary study

Author

Demartini, B, Nistico', V, Tedesco, R, Marzorati, A, Ferrucci, R, Priori, A, Gambini, O, Caputo, G, Demartini B., Nistico' V., Tedesco R., Marzorati A., Ferrucci R., Priori A., Gambini O., Caputo G. B., Demartini, B, Nistico', V, Tedesco, R, Marzorati, A, Ferrucci, R, Priori, A, Gambini, O, Caputo, G, Demartini B., Nistico' V., Tedesco R., Marzorati A., Ferrucci R., Priori A., Gambini O., and Caputo G. B.

Abstract

Purpose: It has been widely shown that dissociative features might play a fundamental role in producing body image distortions in patients affected by eating disorders. Here, we hypothesize that the Mirror Gazing Test (MGT), a task consisting in mirror exposure in a condition of sensory deprivation, would elicit dissociative symptoms in a group of patients with anorexia nervosa (AN). Methods: Fourteen patients with AN and fourteen healthy controls (HC) underwent a 10 min MGT and completed the Strange Face Questionnaire and a short version of the Clinician-Administered Dissociative States Scale, along with a psychological assessment for eating disorders psychopathology, anxiety and depression. Results: AN patients reported a higher number of strange-face apparitions and dissociative sensations than HC during the MGT. Dissociative identity (compartmentalization of two or more identities) and depersonalization (detachment of bodily-self) were much higher in patients with AN than in HC. These findings were correlated with body dissatisfaction and disruption in interoceptive awareness. Conclusion: Dissociation and body image dysfunction are strongly connected in the pathophysiology of anorexia nervosa. Future research should investigate the same aspects in other psychiatric conditions characterized by body image distortions, such as Body Dysmorphic Disorder. Level of evidence: I, Experimental studies.

Published
2021

28. Figure Disembedding: The Gottschaldt's Hidden Figure Test in Children with Typical Development and Autism

Author

Conson M., Siciliano M., Trojano L., Zoccolotti P., Zappullo I., Baiano C., Caputo G., Russo A., Cecere R., Di Rosa A., Esposito G., Milo R., Polito F., Rauso B., Vela M., Santangelo G., Conson, M., Siciliano, M., Trojano, L., Zoccolotti, P., Zappullo, I., Baiano, C., Caputo, G., Russo, A., Cecere, R., Di Rosa, A., Esposito, G., Milo, R., Polito, F., Rauso, B., Vela, M., and Santangelo, G.

Subjects
Perceptual style, Autism Spectrum Disorder, Cognition, medicine.disease, Perception of detail, Large sample, Test (assessment), Developmental psychology, Age groups, Developmental and Educational Psychology, medicine, Normative, Autism, Humans, Hidden figure, Autistic Disorder, Psychology, Child, Time score, Figure disembedding, Socioeconomic differences
Abstract

In two studies, we used the Gottschaldt’s Hidden Figure Test (GHFT) for assessing figure disembedding ability in children aged 7–11. Study 1 demonstrated in a large sample of typically developing children that GHFT accuracy and time scores differed across age groups, without sex and socioeconomic differences. Thus, we provided normative data only taking into account children’s age. In Study 2, GHFT normative values were used to assess children with autism, who were also compared with a closely age-matched group of typical controls. Children with autism achieved time scores at or above the 50th centile and significantly differed from the controls for time score. The GHFT seems a valuable tool for defining the cognitive profile of children with autism.

Published
2021

29. Supercritical water gasification of waste oils as a source of syngas

Author

Maniscalco M., Iannotta P., Scargiali F., Grisafi F., Brucato A., Caputo G., Maniscalco M., Iannotta P., Scargiali F., Grisafi F., Brucato A., and Caputo G.

Subjects
SCWG, supercritical water gasification, waste olis, syngas
Abstract

A huge amount of waste oil is produced worldwide. Also substantial amount of virgin oils is available that are interesting candidates for upgrading into syngas. Supercritical water gasification (SCWG) can be considered as an aqueous phase reforming process to produce syngas from oils. In this work, a variety of waste and virgin oils were gasified in a continuous down-flow autoclave reactor at supercritical conditions. Experiments were carried out at 430 °C and 660 °C, 25 MPa, with a residence time in the range 103-170 s, in order to investigate gasification and carbon efficiency, hydrogen yield and composition of the produced gas. All the analysed feedstocks were suspended in water at various concentrations before gasification. Pyrolysis bio-oil showed a gasification efficiency of 74 % and 86 % for mixtures with 3 and 10 oil/water wt ratio, respectively. Waste motor oil, suspended in water at a concentration of 1 % wt thanks to the use of surfactants, was successfully gasified with a gasification efficiency of 73 %. Virgin motor oil gasification efficiency higher than 60% had been obtained for both analysed concentrations (5 % wt and 10 % wt of oil). Gasification of rapeseed oil at 5 % wt showed a gasification efficiency close to 88 %. On the contrary, the gasification of sunflower oil at 430 °C showed that this temperature is not high enough to obtain acceptable gasification efficiencies that varied from 20 % to 15 % for concentrations of oil from 2 % wt to 8 % wt, respectively. The analysis of the gas composition, in all the studied cases, showed that the obtained gas stream was rich in H2, CH4 and CO2, with variable quantities of light hydrocarbons (C2H4, C2H6 and C3H8).

Published
2021

30. Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups

Author

Ekkapongpisit M, Giovia A, Follo C, Caputo G, and Isidoro C

Subjects
Medicine (General), R5-920
Abstract

Maneerat Ekkapongpisit,1 Antonino Giovia,1 Carlo Follo,1 Giuseppe Caputo,2,3 Ciro Isidoro11Laboratory of Molecular Pathology and Nanobioimaging, Department of Health Sciences, Università del Piemonte Orientale “A Avogadro”, Novara, 2Dipartimento di Chimica dell’Università di Torino, Torino, 3Cyanine Technology SpA, Torino, ItalyBackground and methods: Nanoparticles engineered to carry both a chemotherapeutic drug and a sensitive imaging probe are valid tools for early detection of cancer cells and to monitor the cytotoxic effects of anticancer treatment simultaneously. Here we report on the effect of size (10–30 nm versus 50 nm), type of material (mesoporous silica versus polystyrene), and surface charge functionalization (none, amine groups, or carboxyl groups) on biocompatibility, uptake, compartmentalization, and intracellular retention of fluorescently labeled nanoparticles in cultured human ovarian cancer cells. We also investigated the involvement of caveolae in the mechanism of uptake of nanoparticles.Results: We found that mesoporous silica nanoparticles entered via caveolae-mediated endocytosis and reached the lysosomes; however, while the 50 nm nanoparticles permanently resided within these organelles, the 10 nm nanoparticles soon relocated in the cytoplasm. Naked 10 nm mesoporous silica nanoparticles showed the highest and 50 nm carboxyl-modified mesoporous silica nanoparticles the lowest uptake rates, respectively. Polystyrene nanoparticle uptake also occurred via a caveolae-independent pathway, and was negatively affected by serum. The 30 nm carboxyl-modified polystyrene nanoparticles did not localize in lysosomes and were not toxic, while the 50 nm amine-modified polystyrene nanoparticles accumulated within lysosomes and eventually caused cell death. Ovarian cancer cells expressing caveolin-1 were more likely to endocytose these nanoparticles.Conclusion: These data highlight the importance of considering both the physicochemical characteristics (ie, material, size and surface charge on chemical groups) of nanoparticles and the biochemical composition of the cell membrane when choosing the most suitable nanotheranostics for targeting cancer cells.Keywords: nanoparticles, imaging, lysosomes, vesicular traffic, ovarian cancer, caveolin

Published
2012

31. Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles

Author

Ekkapongpisit M, Giovia A, Nicotra G, Ozzano M, Caputo G, and Isidoro C

Subjects
Medicine (General), R5-920
Abstract

Maneerat Ekkapongpisit1,*, Antonino Giovia1,*, Giuseppina Nicotra1, Matteo Ozzano1, Giuseppe Caputo2,3, Ciro Isidoro1 1Laboratory of Molecular Pathology and Nanobioimaging, Department of Health Sciences, Università del Piemonte Orientale "A. Avogadro", Novara, Italy; 2Department of Chemistry, University of Turin, Turin, 3Cyanine Technology SpA, Torino, Italy *These authors contributed equally to this workBackground: For a safe ‘in vivo’ biomedical utilization of nanoparticles, it is essential to assess not only biocompatibility, but also the potential to trigger unwanted side effects at both cellular and tissue levels. Mastocytes (cells having secretory granules containing cytokines, vasoactive amine, and proteases) play a pivotal role in the immune and inflammatory responses against exogenous toxins. Mastocytes are also recruited in the tumor stroma and are involved in tumor vascularization and growth.Aim and methods: In this work, mastocyte-like rat basophilic leukemia (RBL) cells were used to investigate whether carboxyl-modified 30 nm polystyrene (PS) nanoparticles (NPs) and naked mesoporous silica (MPS) 10 nm NPs are able to label the secretory inflammatory granules, and possibly induce exocytosis of these granules. Uptake, cellular retention and localization of fluorescent NPs were analyzed by cytofluorometry and microscope imaging.Results: Our findings were that: (1) secretory granules of mastocytes are accessible by NPs via endocytosis; (2) PS and MPS silica NPs label two distinct subpopulations of inflammatory granules in RBL mastocytes; and (3) PS NPs induce calcium-dependent exocytosis of inflammatory granules.Conclusion: These findings highlight the value of NPs for live imaging of inflammatory processes, and also have important implications for the clinical use of PS-based NPs, due to their potential to trigger the unwanted activation of mastocytes.Keywords: secretory lysosomes, inflammation, nanoparticles, vesicular traffic

Published
2012

33. Evidence for X(3872) in Pb-Pb Collisions and Studies of its Prompt Production at root s(NN)=5.02 TeV

Author

Sirunyan, A. M., Tumasyan, A., Adam, W., Ambrogi, F., Bergauer, T., Dragicevic, M., Ero, J., Del, Valle, Escalante, A., Flechl, M., Fruhwirth, R., Jeitler, M., Krammer, N., Kratschmer, I, Liko, D., Madlener, T., Mikulec, I, Rad, N., Schieck, J., Schofbeck, R., Spanring, M., Waltenberger, W., Wulz, C-E, Zarucki, M., Drugakov, V, Mossolov, V, Gonzalez, Suarez, J., Darwish, M. R., Wolf, De, E. A., Croce, Di, Janssen, D., Kello, X., Lelek, T., Pieters, A., Sfar, M., Rejeb, H., Van, Haevermaet, Van, Mechelen, Van, Putte, Van, Remortel, Blekman, N., Bols, F., Chhibra, E. S., D'Hondt, S. S., Clercq, De, Lontkovskyi, J., Lowette, D., Marchesini, S., Moortgat, I, Python, S., Tavernier, Q., Van, Doninck, Van, Mulders, Beghin, P., Bilin, D., Clerbaux, B., Lentdecker, De, Delannoy, G., Dorney, H., Favart, B., Grebenyuk, L., Kalsi, A., Moureaux, A. K., Popov, L., Postiau, A., Starling, N., Thomas, E., L. V., Velde, Er, Vanlaer, C., Vannerom, P., Cornelis, D., Dobur, T., Khvastunov, D., Niedziela, I, Roskas, M., Skovpen, C., Tytgat, K., Verbeke, M., Vermassen, W., Vit, B., Bruno, M., Caputo, G., David, C., Delaere, P., Delcourt, C., Giammanco, M., Lemaitre, A., Prisci, V, Aro, J., Saggio, A., Vischia, P., Zobec, J., Alves, G. A., Silva, Correia, G., Hensel, C., Moraes, A., Batista Das Chagas, Belchior, E., Carvalho, W., Chinellato, J., Coelho, E., Costa, Da, E. M., Silveira, Da, Damiao, G. G., De Jesus, D., Martins, De Oliveira, C., Souza, De, Fonseca, S., Malbouisson, H., Martins, J., Figueiredo, Matos, D., Jaime, Medina, M., Almeida, De, Melo, M., Herrera, Mora, C., Mundim, L., Nogima, H., Prado Da Silva, Teles, W. L., Rebello, P., Rosas, Sanchez, L. J., Santoro, A., Sznajder, A., Thiel, M., Tonelli, Manganote, E. J., Da Silva De Araujo, Torres, F., Pereira, Vilela, A., Bernardes, C. A., Calligaris, L., Fern, ez Perez Tomei, Gregores, T. R., Lemos, E. M., Mercadante, D. S., Novaes, P. G., Padula, S. F., S, Ra, S., Aleks, Rov, Antchev, A., Hadjiiska, G., Iaydjiev, R., Misheva, P., Rodozov, M., Shopova, M., Sultanov, M., Bonchev, G., Dimitrov, M., Ivanov, A., Litov, T., Pavlov, L., Petkov, B., Petrov, P., Fang, A., Gao, W., Yuan, X., Ahmad, L., Hu, M., Wang, Z., Chen, Y., Chen, G. M., Chen, H. S., Jiang, M., Leggat, C. H., Liao, D., Liu, H., Spiezia, Z., Tao, A., Yazgan, J., Zhang, E., Zhang, H., Zhao, S., Agapitos, J., Ban, A., Levin, G., Li, A., Li, J., Li, L., Mao, Q., Qian, Y., Wang, S. J., Wang, D., Xiao, Q., Avila, M., Cabrera, C., Florez, A., Gonzalez, Hern, C. F., Ez, Segura, Delgado, M. A., Mejia, Guisao, Ruiz, Alvarez, J. D., Salazar, Gonzalez, C. A., Vanegas, Arbelaez, Godinovic, N., Lelas, N., Puljak, D., Sculac, I, Antunovic, T., Kovac, Z., Brigljevic, M., Ferencek, V, Kadija, D., Mesic, K., Roguljic, B., Starodumov, M., Susa, A., Ather, T., Attikis, M. W., Erodotou, A., Ioannou, E., Kolosova, A., Konstantinou, M., Mavromanolakis, S., Mousa, G., Nicolaou, J., Ptochos, C., Razis, F., Rykaczewski, P. A., Saka, H., Tsiakkouri, H., Finger, D., Finger, M., r. M., J, Kveton, A., Tomsa, J., Ayala, E., Jarrin, Carrera, E., Mahmoud, M. A., Mohammed, Y., Bhowmik, S., Antunes De Oliveira, Carvalho, A., Dewanjee, R. K., Ehataht, K., Kadastik, M., Raidal, M., Veelken, C., Eerola, P., Forthomme, L., Kirschenmann, H., Osterberg, K., Voutilainen, M., Garcia, F., Havukainen, J., Heikkila, J. K., Karimaki, V, Kim, M. S., Kinnunen, R., Lampen, T., Lassila-Perini, K., Laurila, S., Lehti, S., Linden, T., Siikonen, H., Tuominen, E., Tuominiemi, J., Luukka, P., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Fabbro, B., Faure, J. L., Ferri, F., Ganjour, S., Givernaud, A., Gras, P., Monchenault, De, Hamel, G., Jarry, P., Leloup, C., Lenzi, B., Locci, E., Malcles, J., R, Er, Rosowsky, J., Sahin, A., Savoy-Navarro, M. O., Titov, A., Yu, M., Ahuja, G. B., Amendola, S., Beaudette, C., Bonanomi, F., Busson, M., Charlot, P., Diab, C., Falmagne, B., Cassagnac, De, Granier, R., Kucher, I, Lobanov, A., Perez, Martin, C., Nguyen, M., Och, O, Paganini, C., Rembser, P., Salerno, J., Sauvan, R., Sirois, J. B., Zabi, Y., Zghiche, A., Agram, A., J-L, Rea, Bloch, J., Bourgatte, D., Brom, G., J-M, Chabert, Collard, E. C., Conte, C., Fontaine, E., J-C, Gele, Goerlach, D., Grimault, U., Bihan, Le, A-C, Tonon, Van, Hove, Gadrat, P., Beauceron, S., Bernet, S., Boudoul, C., Camen, G., Carle, C., Chanon, A., Chierici, N., Contardo, R., Depasse, D., Mamouni, El, Fay, H., Gascon, J., Gouzevitch, S., Ille, M., Jain, B., Laktineh, Sa, Lattaud, I. B., Lesauvage, H., Lethuillier, A., Mirabito, M., Perries, L., Sordini, S., Torterotot, V, Touquet, L., G. V., Donckt, Er, Viret, M., Toriashvili, S., Tsamalaidze, T., Autermann, Z., Feld, C., Klein, L., Lipinski, K., Meuser, M., Pauls, D., Preuten, A., Rauch, M., Schulz, M. P., Teroerde, J., Erdmann, M., Fischer, M., Ghosh, B., Hebbeker, S., Hoepfner, T., Keller, K., Mastrolorenzo, H., Merschmeyer, L., Meyer, M., Millet, A., Mocellin, P., Mondal, G., Mukherjee, S., Noll, S., Novak, D., Pook, A., Pozdnyakov, T., Quast, A., Radziej, T., Rath, M., Reithler, Y., Roemer, H., Schmidt, J., Schuler, A., Sharma, S. C., Wiedenbeck, A., Zaleski, S., Flugge, S., Ahmad, G., Haj, W., Hlushchenko, O., Kress, T., Muller, T., Nowack, A., Pistone, C., Pooth, O., Roy, D., Sert, H., Stahl, A., Martin, Aldaya, M., Asmuss, P., Babounikau, I, Bakhshiansohi, H., Beernaert, K., Behnke, O., Martinez, Bermudez, A., Bin, Anuar, Borras, A. A., Botta, K., Campbell, V, Cardini, A., Connor, A., Rodriguez, P., Consuegra, S., Contreras-Campana, C., Danilov, V, Wit, De, Defranchis, A., Pardos, M. M., Diez, C., Damiani, Dominguez, D., Eckerlin, G., Eckstein, D., Eichhorn, T., Elwood, A., Eren, E., Banos, Estevez, L. I., Gallo, E., Geiser, A., Grohsjean, A., Guthoff, M., Haranko, M., Harb, A., Jafari, A., Jomhari, N. Z., Jung, H., Kasem, A., Kasemann, M., Kaveh, H., Keaveney, J., Kleinwort, C., Knolle, J., Krucker, D., Lange, W., Lenz, T., Lidrych, J., Lipka, K., Lohmann, W., Mankel, R., Melzer-Pellmann, I-A, Meyer, A. B., Missiroli, M., Mnich, J., Mussgiller, A., Myronenko, V, Adan, Perez, D., Pflitsch, S. K., Pitzl, D., Raspereza, A., Saibel, A., Savitskyi, M., Scheurer, V, Schutze, P., Schwanenberger, C., Shevchenko, R., Singh, A., Ricardo, Sosa, R. E., Tholen, H., Turkot, O., Vagnerini, A., Van De Klundert, Walsh, M., Wen, R., Wichmann, Y., Wissing, K., Zenaiev, C., Zlebcik, O., Aggleton, R., Bein, R., Benato, S., Benecke, L., Dreyer, A., Ebrahimi, T., Feindt, A., Frohlich, F., Garbers, A., Garutti, C., Gonzalez, E., Gunnellini, D., Haller, P., Hinzmann, J., Karavdina, A., Kasieczka, A., Klanner, G., Kogler, R., Kovalchuk, R., Kurz, N., Kutzner, S., Lange, V, Lange, J., Malara, T., Multhaup, A., Niemeyer, J., Reimers, C. E. N., Rieger, A., Schleper, O., Schumann, P., Schw, S., T, J., Sonneveld, J., Stadie, H., Steinbruck, G., Vormwald, B., Zoi, I, Akbiyik, M., Baselga, M., Baur, S., Berger, T., Butz, E., Caspart, R., Chwalek, T., Boer, De, Dierlamm, W., Morabit, El, Faltermann, K., Giffels, N., Gottmann, M., Hartmann, A., Heidecker, F., Husemann, C., Iqbal, U., Kudella, M. A., Maier, S., Mitra, S., Mozer, S., Muller, M. U., Muller, D., Musich, Th, Nurnberg, M., Rabbertz, G., Savoiu, K., Schafer, D., Schnepf, D., Schroder, M., Shvetsov, M., Simonis, I, Ulrich, H. J., Wassmer, R., Weber, M., Wohrmann, M., Wolf, C., Wozniewski, R., Anagnostou, S., Asenov, G., Daskalakis, P., Geralis, G., Kyriakis, T., Loukas, A., Paspalaki, D., Stakia, G., Diamantopoulou, A., Karathanasis, M., Kontaxakis, G., Manousakis-katsikakis, P., Panagiotou, A., Papavergou, A., Saoulidou, I, Theofilatos, N., Vellidis, K., Vourliotis, K., Bakas, E., Kousouris, G., Papakrivopoulos, K., Tsipolitis, I, Zacharopoulou, G., Evangelou, A., Foudas, I, Gianneios, C., Katsoulis, P., Kokkas, P., Mallios, P., Manitara, S., Manthos, K., Papadopoulos, N., Strologas, I, Triantis, J., Tsitsonis, F. A., Bartok, D., Chudasama, M., Csanad, R., Major, M., P. M., Al, K., Mehta, A., Pasztor, G., Suranyi, O., Veres, I, Bencze, G., Hajdu, G., Horvath, C., Sikler, D., Veszpremi, F., Vesztergombi, V., Beni, G., Czellar, N., Karancsi, S., Molnar, J., Szillasi, J., Raics, Z., Teyssier, P., Trocsanyi, D., Ujvari, Z. L., Csorgo, B., Metzger, T., Nemes, W. J., Novak, F., Choudhury, T., Komaragiri, S., Tiwari, J. R., Bahinipati, P. C., Kar, S., Kole, C., Mal, G., Bindhu, P., Muraleedharan Nair, V. K., Nayak, A., Sahoo, D. K., Swain, S. K., Bansal, S., Beri, S. B., Bhatnagar, V, Chauhan, S., Dhingra, N., Gupta, R., Kaur, A., Kaur, M., Kaur, S., Kumari, P., Lohan, M., Meena, M., Eep, S, Sharma, K., Singh, S., Virdi, J. B., Walia, A. K., Bhardwaj, G., Choudhary, A., Garg, B. C., Gola, R. 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E., Sturdy, N., Thapa, J., Black, P., Bose, K., Buchanan, T., Caillol, J., Carlsmith, C., Dasu, D., Bruyn, De, Dodd, I, Galloni, L., He, C., Herndon, H., Herve, M., Hussain, A., Lanaro, U., Loeliger, A., Loveless, A., Sreekala, R., Madhusudanan, J., Mallampalli, A., Pinna, D., Ruggles, T., Savin, A., Sharma, V, Smith, W. H., Teague, D., Trembath-reichert, S., and Cms, Collaboration

Subjects
MODEL, Physics and Astronomy, High Energy Physics::Experiment, QUARK-GLUON PLASMA, Nuclear Experiment
Abstract

The first evidence for X(3872) production in relativistic heavy ion collisions is reported. The X(3872) production is studied in lead-lead (Pb-Pb) collisions at a center-of-mass energy of root s(NN) = 5.02 TeV per nucleon pair, using the decay chain X(3872) -> J/psi pi(+)pi(-) -> mu(+) mu(-) pi(+)pi(-). The data were recorded with the CMS detector in 2018 and correspond to an integrated luminosity of 1.7 nb(-1). The measurement is performed in the rapidity and transverse momentum ranges vertical bar y vertical bar < 1.6 and 15 < p(T) < 50 GeV/c. The significance of the inclusive X(3872) signal is 4.2 standard deviations. The prompt X(3872) to psi 2S yield ratio is found to be rho(Pb-Pb) = 1.08 +/- 0.49(stat) +/- 0.52(syst), to be compared with typical values of 0.1 for pp collisions. This result provides a unique experimental input to theoretical models of the X(3872) production mechanism, and of the nature of this exotic state.

Published
2022

35. Dissociation during Mirror Gazing Test in psychogenic nonepileptic seizures and functional movement disorders

Author

Nistico', V, Caputo, G, Tedesco, R, Marzorati, A, Ferrucci, R, Priori, A, Gambini, O, Demartini, B, Nistico' V., Caputo G., Tedesco R., Marzorati A., Ferrucci R., Priori A., Gambini O., Demartini B., Nistico', V, Caputo, G, Tedesco, R, Marzorati, A, Ferrucci, R, Priori, A, Gambini, O, Demartini, B, Nistico' V., Caputo G., Tedesco R., Marzorati A., Ferrucci R., Priori A., Gambini O., and Demartini B.

Abstract

Introduction: Psychogenic nonepileptic seizures (PNES) and functional movement disorders (FMD) seem to represent the two ends of a continuum where different clinical phenotypes represent the manifestation of a common framework, involving dissociation. The aim of the present study was to assess dissociation and its subcomponents through the Mirror Gazing Test (MGT) in these functional neurological disorders (FNDs). Materials and methods: Eleven patients with PNES, 17 with FMD, and 18 healthy controls (HCs) underwent a 10-minute MGT and completed the Strange Face Questionnaire (SFQ), an ad-hoc questionnaire assessing the sensations and perceptions they had looking in the mirror, and a short version of the Clinician-Administered Dissociative States Scale (CADSS). Results: Patients with PNES, FMD, and HCs did not differ at the total score of the SFQ. Patients with PNES scored higher than HCs at the SFQ-subscale Dissociative Identity/Compartmentalization, at the CADSS Total Score and at its subscale Dissociative Amnesia, while patients with FMD scored higher than HCs at the CADSS subscale Depersonalization. Conclusions: Patients with FMD reported more sensations falling in the detachment facet of dissociation, while patients with PNES in the compartmentalization one. We hypothesized that both facets of dissociation might be important pathophysiological processes for PNES and FMD and that different instruments (self-report clinical scales vs experimental tasks) might be able to detect different facets in different populations because they assess, respectively, “trait” and “state” dissociation.

Published
2020

45. Combining dietary phenolic antioxidants with polyvinylpyrrolidone: Transparent biopolymer films based on: P-coumaric acid for controlled release

Author

Contardi, M, Heredia-Guerrero, J, Guzman-Puyol, S, Summa, M, Benitez, J, Goldoni, L, Caputo, G, Cusimano, G, Picone, P, Di Carlo, M, Bertorelli, R, Athanassiou, A, Bayer, I, Contardi M., Heredia-Guerrero J. A., Guzman-Puyol S., Summa M., Benitez J. J., Goldoni L., Caputo G., Cusimano G., Picone P., Di Carlo M., Bertorelli R., Athanassiou A., Bayer I. S., Contardi, M, Heredia-Guerrero, J, Guzman-Puyol, S, Summa, M, Benitez, J, Goldoni, L, Caputo, G, Cusimano, G, Picone, P, Di Carlo, M, Bertorelli, R, Athanassiou, A, Bayer, I, Contardi M., Heredia-Guerrero J. A., Guzman-Puyol S., Summa M., Benitez J. J., Goldoni L., Caputo G., Cusimano G., Picone P., Di Carlo M., Bertorelli R., Athanassiou A., and Bayer I. S.

Abstract

Polyvinylpyrrolidone (PVP) has probably been one of the most utilized pharmaceutical polymers with applications ranging from a blood plasma substitute to nanoparticle drug delivery, since its synthesis in 1939. It is a highly biocompatible, non-toxic and transparent film forming polymer. Although high solubility of PVP in aqueous environment is advantageous, it still poses several problems for some applications in which sustained targeting and release are needed or hydrophobic drug inclusion and delivery systems are to be designed. In this study, we demonstrate that a common dietary phenolic antioxidant, p-coumaric acid (PCA), can be combined with PVP covering a wide range of molar ratios by solution blending in ethanol, forming new transparent biomaterial films with antiseptic and antioxidant properties. PCA not only acts as an effective natural plasticizer but also establishes H-bonds with PVP increasing its resistance to water dissolution. PCA could be released in a sustained manner up to a period of 3 days depending on the PVP/PCA molar ratio. Sustained drug delivery potential of the films was studied using methylene blue and carminic acid as model drugs, indicating that the release can be controlled. Antioxidant and remodeling properties of the films were evaluated in vitro by free radical cation scavenging assay and in vivo on a murine model, respectively. Furthermore, the material resorption of films was slower as PCA concentration increased, as observed from the in vivo full-thickness excision model. Finally, the antibacterial activity of the films against common pathogens such as Escherichia coli and Staphylococcus aureus and the effective reduction of inflammatory agents such as matrix metallopeptidases were demonstrated. All these properties suggest that these new transparent PVP/PCA films can find a plethora of applications in pharmaceutical sciences including skin and wound care.

Published
2019

46. Locally advanced breast implant-associated anaplastic large-cell lymphoma: A combined medical-surgical approach

Author

Caputo, G. G., Alban, A., D'Ali, L., Mariuzzi, L., Galvano, F., and Parodi, P. C.

Subjects
Brentuximab Vedotin, Lymphoma, Textured breast implant, Antineoplastic Agents, Breast Neoplasms, Neoadjuvant therapy in BIA-ALCL, Neoadjuvant Therapy, Large-Cell, Vincristine, Positron Emission Tomography Computed Tomography, Humans, Anaplastic, BIA-ALCL, Female, Immunotherapy, Breast implant anaplastic cell lymphoma, Lymphoma, Large-Cell, Anaplastic, Mastectomy
Published
2021

48. Contributor contact details

Author

Gugliuzza, A., primary, Basile, A., additional, Damle, A., additional, Charcosset, C., additional, Piemonte, V., additional, Di Paola, L., additional, Curcio, S., additional, Ricca, E., additional, Blasi, A., additional, Fiorenza, G., additional, Freda, C., additional, Calabrò, V., additional, da Costa, J., additional, Smart, S., additional, Liu, S., additional, Serra, J.M., additional, Genovese, A., additional, Villante, C., additional, Lo Faro, M., additional, Aricò, A.S., additional, Scott, K., additional, Cigolotti, V., additional, Devianto, H., additional, McPhail, S., additional, Moreno, A., additional, Giaconia, A., additional, Caputo, G., additional, Gugliuzza, A., additional, Capriccioli, A., additional, and Gormly, S., additional

Published
2014
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