104 results on '"Caravelli S."'
Search Results
2. Posture and vision: How different distances of viewing target affect postural stability and plantar pressure parameters in healthy population
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De Blasiis, P., Fullin, A., De Girolamo, C.I., Amata, O., Caravaggi, P., Caravelli, S., Mosca, M., and Lucariello, A.
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- 2024
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3. Orthopaedic and plastic surgery collaboration in resolution of plantar heloma and metatarsalgia using lipofilling: a retrospective evaluation
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Iannuzzi, R., Caravelli, S., Pungetti, C., Di Ponte, M., Zaffagnini, S., and Mosca, M.
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- 2023
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4. Hallux valgus associated to osteoarthritis: Clinical-radiological outcomes of modified SERI technique at mid- to long-term follow-up. A retrospective analysis
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Mosca, M., Caravelli, S., Vocale, E., Fuiano, M., Massimi, S., Di Ponte, M., Censoni, D., Grassi, A., Ceccarelli, F., and Zaffagnini, S.
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- 2022
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5. Management of high-grade hallux rigidus: a narrative review of the literature
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Massimi, S., Caravelli, S., Fuiano, M., Pungetti, C., Mosca, M., and Zaffagnini, S.
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- 2020
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6. A comprehensive and narrative review of historical aspects and management of low-grade hallux rigidus: conservative and surgical possibilities
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Caravelli, S., Mosca, M., Massimi, S., Pungetti, C., Russo, A., Fuiano, M., Catanese, G., and Zaffagnini, S.
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- 2018
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7. Percutaneous treatment of hallux valgus: What’s the evidence? A systematic review
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Caravelli, S., Mosca, M., Massimi, S., Costa, G. G., Lo Presti, M., Fuiano, M., Grassi, A., and Zaffagnini, S.
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- 2018
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8. Percutaneous treatment of hallux valgus: What’s the evidence? A systematic review
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Caravelli, S., primary, Mosca, M., additional, Massimi, S., additional, Costa, G. G., additional, Lo Presti, M., additional, Fuiano, M., additional, Grassi, A., additional, and Zaffagnini, S., additional
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- 2017
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9. 2-01-06 Neuropepidemiologic characteristics of the population of HIV-seropositive patients at the Torno hospital, over the 1992–1996 period
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Klajn, D., primary, Burgos, M., additional, Alleva, A., additional, Vozza, J., additional, Molina, A., additional, and Caravelli, S., additional
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- 1997
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10. Enhanced recovery (fast-track surgery) after total ankle replacement: The state of the art
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Lorenzo Querci, Silvio Caravelli, Marco Di Ponte, Mario Fuiano, Paolo De Blasiis, Felice Sirico, Annalisa Baiardi, Francesca Zannoni, Massimiliano Mosca, Querci, L., Caravelli, S., Di Ponte, M., Fuiano, M., De Blasiis, P., Sirico, F., Baiardi, A., Zannoni, F., and Mosca, M.
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Postoperative Care ,Arthroplasty, Replacement, Ankle ,Rehabilitation ,Humans ,Anestesiology ,Total ankle replacement ,Orthopedics and Sports Medicine ,Recovery of Function ,Postoperative Period ,Length of Stay ,Fast track - Abstract
The post-operative results of a total ankle replacement are not determined solely by an optimal surgical technique, but by an appropriate anesthesiological and rehabilitative post-operative approach. Enhanced functional recovery often depends on a multidisciplinary approach based on a correct framework of the patient and his needs, requests, and characteristics. Extensive bibliographical research has been performed on Pubmed, Google Scholar, Scopus. This comprehensive and inclusive review of the literature aims to examine the state of the art of "fast-track" protocols employed in total ankle replacement (TAR), considering pre-operative preparation, anesthetic management, intraoperative and surgical factors, post-operative rehabilitative care and reduction of hospitalization time.
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- 2022
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11. Ruptures of the Plantar Fascia: A Systematic Review of the Literature
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Stefano Zaffagnini, Davide Censoni, Simone Massimi, Alberto Grassi, Massimiliano Mosca, Giuseppe Catanese, Mario Fuiano, Silvio Caravelli, Mosca M., Fuiano M., Massimi S., Censoni D., Catanese G., Grassi A., Caravelli S., and Zaffagnini S.
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medicine.medical_specialty ,review ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,sports traumatology ,Orthopedics and Sports Medicine ,Fascia ,Podiatry ,030222 orthopedics ,Rupture, Spontaneous ,plantar fascia ,biology ,Foot ,Athletes ,business.industry ,030229 sport sciences ,biology.organism_classification ,body regions ,medicine.anatomical_structure ,Fasciitis, Plantar ,treatments ,Physical therapy ,rupture ,Surgery ,Plantar fascia ,business - Abstract
Introduction Rupture of the plantar fascia is a rare condition. It can also occur spontaneously and with no history of disease of the plantar fascia, above all in athletes. This review aims to systematically analyze all cases described in the literature regarding the rupture of the plantar fascia, evaluating incidence, risk factors, and treatments, considering which procedures show the best outcomes and the highest success rate. Materials and methods A systematic review of PubMed, Google Scholar, and Cochrane review computerized databases was performed, focusing on articles about cases of rupture of the plantar fascia; 18 studies fulfilled all the criteria and were analyzed. There were no randomized controlled trials. Results A total of 155 patients (157 foot) were included in this systematic review. Considering all the studies included, 12 patients had a spontaneous rupture, 138 patients had a diagnosis of plantar fasciitis, and 130 patients were treated with local injections of corticosteroid before the rupture. Only 2 cases of bilateral rupture were reported. In all, 15 studies reported conservative treatment, with a total of 154 patients (156 feet) included. Operative treatment was reported in 3 studies, with 3 patients (3 feet) treated. Conclusions Ruptures of the plantar fascia are very rare in asymptomatic patients and more common in patients treated with injection of steroids in the plantar fascia. Conservative treatment, although not standardized in the literature, led to good outcomes in most cases. Chronic ruptures of the fascia should be considered for operative treatment. Levels of Evidence: Level III
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- 2020
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12. Callus distraction with external fixator for the treatment of congenital brachymetatarsia of the fourth ray
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Michele Di Liddo, Giuseppe Catanese, Mario Fuiano, Silvio Caravelli, Aditi Majumdar, Simone Massimi, Alberto Grassi, Massimiliano Mosca, Stefano Zaffagnini, Fuiano M., Mosca M., Caravelli S., Di Liddo M., Grassi A., Majumdar A., Massimi S., Catanese G., and Zaffagnini S.
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Adult ,Male ,medicine.medical_specialty ,External fixator ,External Fixators ,Foot Deformities, Congenital ,medicine.medical_treatment ,Radiography ,Osteogenesis, Distraction ,Callotaxi ,Brachymetatarsia ,Young Adult ,03 medical and health sciences ,External fixation ,0302 clinical medicine ,Distraction ,medicine ,Humans ,Orthopedics and Sports Medicine ,Metatarsal Bones ,Fourth ,030222 orthopedics ,business.industry ,Forefoot ,Fourth ray ,030229 sport sciences ,medicine.disease ,Surgery ,Osteotome ,Female ,business - Abstract
Background Brachymetatarsia is a rare abnormality of the foot which occurs most frequently in the first and fourth metatarsals. The aim of this study was to evaluate the efficacy of gradual metatarsal lengthening by external fixator for treatment of brachymetatarsia of the fourth ray. The hypothesis was that with external fixation it would be possible to achieve the desired length of the metatarsal with a low rate of complications. Secondarily, in cases requiring a greater amount of correction, it was hypothesized that an opportune rate of bone consolidation would be achievable using a traditional oscillating saw without predrilling or use of a cold osteotome. Methods Between 2013 and 2016, 12 eligible patients and 13 feet underwent gradual metatarsal lengthening by an external fixator (MiniRail System M103, Orthofix) due to brachymetatarsia of the fourth ray. Mean age at surgery was 24.5 ± 5.3 years (range 19–36), with mean follow-up of 22.3 ± 8.3 months. Clinical evaluation was performed with the AOFAS lesser metatarsophalangeal-interphalangeal (MTP-IP) score. Radiographic assessment was performed on follow-up using non-weightbearing dorsoplantar foot radiographs. Results The mean AOFAS lesser MTP-IP score improved from a preoperative score of 76.6 ± 7.1 points (range 62–85 points) to a postoperative score of 90.3 ± 3.0 points (range 86–95 points). The average amount of lengthening was 16.8 ± 3.9 mm (range 8–22 mm). Mean shortening, final lengthening, Healing Index, period of treatment, and complications are also reported. The operative technique is described. Conclusions Gradual metatarsal lengthening with external fixator is an effective treatment for brachymetatarsia and can restore forefoot anatomy with good clinical outcomes, a low rate of morbidity and complications in selected cases. Particular attention should be given when treating patients with shortening >20 mm.
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- 2020
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13. Tibiotalocalcaneal arthrodesis through retrograde nailing for the treatment of juxtaarticular distal tibia aseptic non-unions: A retrospective study at a minimum follow-up of 4 years
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Francesco Ceccarelli, Massimiliano Mosca, Mario Fuiano, Alberto Grassi, Simone Massimi, Silvio Caravelli, Stefano Zaffagnini, Emanuele Vocale, Davide Censoni, Mosca M., Caravelli S., Fuiano M., Massimi S., Censoni D., Grassi A., Vocale E., Ceccarelli F., and Zaffagnini S.
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Adult ,Male ,medicine.medical_specialty ,Nonunion ,Arthrodesis ,Osteoarthritis ,Bone Nails ,Distal tibia ,Talus ,law.invention ,Foot Diseases ,Intramedullary rod ,03 medical and health sciences ,0302 clinical medicine ,law ,Humans ,Medicine ,Aged ,Retrospective Studies ,General Environmental Science ,030222 orthopedics ,Tibia ,business.industry ,Retrograde nail ,Subtalar Joint ,030208 emergency & critical care medicine ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Fracture Fixation, Intramedullary ,Surgery ,Radiography ,Calcaneus ,medicine.anatomical_structure ,General Earth and Planetary Sciences ,Osteoarthriti ,Female ,Tibiotalocalcaneal arthrodesis ,Aseptic processing ,Juxta-articular ,Ankle ,business ,Ankle Joint ,Follow-Up Studies - Abstract
Introduction The purpose of this study is to determine the efficacy of tibiotalocalcaneal arthrodesis by reamed intramedullary nail in the management of the distal tibia non-unions, associated with end-stage osteoarthritis of ankle and subtalar joints. Materials and methods 8 patients with radiographical and clinical diagnosis of non-union of the distal tibia have been treated with tibiotalocalcaneal arthrodesis by intramedullary retrograde nail and were retrospectively evaluated. Patients were radiographically and clinically evaluated preoperatively and at final follow-up regarding: satisfaction, AOFAS, VAS. Surgical technique is described. Results Mean follow-up was 69.2 ± 23.2 months (range 48–108). In terms of subjective outcome, patients reported a highly satisfying result. All patients returned to daily activities, with an average time of 24.7 ± 8.7 weeks. 6 patients could return to their previous work activity, with an average time of 23.6 ± 6.3 weeks. Conclusions The procedure showed good results at final follow up. Consolidation was achieved in all the treated cases. Considering AOFAS and VAS scores at final follow-up, there was an evident improvement of the conditions of the patients.
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- 2020
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14. Management of early ankle osteoarthritis through anterior joint-preserving surgery: a retrospective evaluation at mid- to long-term follow-up
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Silvio Caravelli, Francesco Ceccarelli, Danila Oldani, Massimiliano Mosca, Mario Fuiano, Stefano Zaffagnini, Simone Massimi, Alberto Grassi, Laura Rossi, Mosca M., Caravelli S., Fuiano M., Massimi S., Oldani D., Rossi L., Grassi A., Zaffagnini S., and Ceccarelli F.
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medicine.medical_specialty ,Open ,medicine.medical_treatment ,Arthrodesis ,Ankle replacement ,Context (language use) ,Osteoarthritis ,Statistical significance ,medicine ,Humans ,Orthopedics and Sports Medicine ,Ankle pain ,Retrospective Studies ,business.industry ,Infant, Newborn ,Retrospective cohort study ,Anterior impingement ,Arthrolysi ,medicine.disease ,Surgery ,Treatment Outcome ,medicine.anatomical_structure ,Ankle ,business ,Ankle Joint ,Follow-Up Studies - Abstract
Purpose: Chronic anterior ankle pain is a recognized and straightforward characteristic of anterior impingement syndrome. This retrospective study aims to evaluate outcomes, clinical and radiological results in patients affected by anterior ankle impingement, in a context of early osteoarthritis, and treated with mini-open anterior ankle arthrolysis, in the perspective to delay or avoid other demolitive surgical options, such as total ankle replacement and joint fusion. Methods: In total, 49 patients (50 feet, mean age 45years) undergone mini-open anterior ankle arthrolysis for anterior impingement, fulfilled inclusion criteria and gave their consent and have been enlisted in the study. Patients were retrospectively reviewed with AOFAS ankle-hindfoot score and SF-36 score at a minimum follow-up of 36months. Statistical analysis was performed. Results: A marked improvement was noticed in terms of preoperative clinical score (mean AOFAS score 47.32 ± 17.89) compared to follow-up clinical score (mean AOFAS score 70.66 ± 16.62; p ' 0.005), and all of 8 SF-36 domains showed statistically improved (p ' 0.05) from preoperative to follow-up. Statistical significance has been shown. Conclusions: It is possible to consider the mini-open anterior arthrolysis, thanks to the reduction of the painful symptomatology, a valid tool for procrastinating more invasive interventions such as arthrodesis or prosthetic replacement in patients with grade 1 or 2 of ankle osteoarthritis.
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- 2020
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15. Achilles tendon reconstruction with peroneus tendon transfer following epithelioid sarcoma resection: a rare case report at 5 years follow-up
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Massimiliano Mosca, Simone Massimi, Federica Mariotti, Silvio Caravelli, Stefano Zaffagnini, Roberto Casadei, Mariotti F., Caravelli S., Mosca M., Massimi S., Casadei R., and Zaffagnini S.
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medicine.medical_specialty ,Epithelioid sarcoma ,medicine.medical_treatment ,Short Report ,Resection ,03 medical and health sciences ,0302 clinical medicine ,lcsh:Orthopedic surgery ,Tendon transfer ,medicine ,Orthopedics and Sports Medicine ,030222 orthopedics ,Achilles tendon ,business.industry ,Soft tissue ,Anatomy ,Fascia ,epithelioid sarcoma resection ,medicine.disease ,musculoskeletal system ,Tendon ,peroneus tendon transfer ,lcsh:RD701-811 ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Orthopedic surgery ,business - Abstract
Background Soft-tissue sarcomas (STS) are rare in hand and foot. In this paper we present a case of reconstruction of Achilles tendon defect with peroneus brevis transfer reinforced with medial gastrocnemius fascia and plantaris tendon after excision of a local recurrence of epithelioid sarcoma. Case presentation Fifty-five years-old female. MRI showed a lump of 5 × 2,5 × 2 cm into Achille’s tendon with invasion of the anterior fat tissue but no invasion of the surrounding bones. The patient underwent excision of the tumour and reconstruction of the tendinous defect with peroneus brevis transfer. Surgical technique has been widely described. Discussion and conclusions Epithelioid sarcoma arising from the Achilles tendon is an extremely rare malignant tumour in an atypical site and may easily be confused with other soft tissue masses. It presents a technical challenge because of the large tendon defect remaining following wide resection. Reconstruction with peroneus brevis transfer, reinforced with medial gastrocnemius fascia and plantaris tendon, restore appropriate structural continuity and resistance. Functional results are satisfactory.
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- 2020
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16. Variability of Postural Stability and Plantar Pressure Parameters in Healthy Subjects Evaluated by a Novel Pressure Plate
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Allegra Fullin, Paolo Caravaggi, Pietro Picerno, Massimiliano Mosca, Silvio Caravelli, Antonio De Luca, Angela Lucariello, Paolo De Blasiis, Fullin, A., Caravaggi, P., Picerno, P., Mosca, M., Caravelli, S., De Luca, A., Lucariello, A., and De Blasiis, P.
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Pressure plate ,Foot ,Health, Toxicology and Mutagenesis ,Posture ,Public Health, Environmental and Occupational Health ,Postural stability ,Stabilometry ,Accuracy ,Baropodometry ,Plantar pressure ,Repeatability ,Healthy Volunteer ,Healthy Volunteers ,Lower Extremity ,postural stability ,posture ,plantar pressure ,pressure plate ,accuracy ,repeatability ,baropodometry ,stabilometry ,Humans ,Postural Balance ,Human - Abstract
Background: Postural stability and plantar pressure parameters can be assessed by baropodometry; nevertheless, they are often affected by low repeatability. The aim of the study was to test the accuracy and repeatability of a novel resistive sensor pressure plate and to establish the most reliable baropodometric parameters. Methods: Accuracy and repeatability of the FM12050 BTS-Bioengineering plate measurements were assessed by using different weights in static conditions across three sessions. Subsequently, 20 healthy subjects were assessed by 30-s stabilometric analysis in bipedal standing with open eyes across four trials in two sessions, morning and afternoon. Results: Pressure plate repeatability in measuring the static weights was very high, and plate measurements were correlated to the scale measurements (Pearson’s coefficient = 0.99). Percentage of load distribution between left and right foot and in rearfoot and forefoot regions showed the largest repeatability (coefficient of variation < 5%) across trials. Eventually, median and percentiles (25–75%) were reported for each parameter. Conclusions: This study helped to assess the accuracy and repeatability of a novel pressure plate in static conditions and to define the most reliable parameters for the assessment of postural stability and foot morphology. The present healthy-subject stabilometric dataset may be used as reference data in the evaluation of pathological populations.
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- 2022
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17. Clinical Radiographical Outcomes and Complications after a Brand-New Total Ankle Replacement Design through an Anterior Approach: A Retrospective at a Short-Term Follow Up
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Massimiliano Mosca, Marco Di Ponte, Emanuele Vocale, Silvio Caravelli, Stefano Zaffagnini, Simone Massimi, Mario Fuiano, Davide Censoni, Mosca M., Caravelli S., Vocale E., Massimi S., Censoni D., Di Ponte M., Fuiano M., and Zaffagnini S.
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Ankle osteoarthritis ,medicine.medical_specialty ,total ankle replacement ,medicine.medical_treatment ,Radiography ,end-stage osteoarthritis ,Ankle replacement ,New design prosthesi ,anterior approach ,Article ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Vas score ,030222 orthopedics ,business.industry ,Mean value ,030229 sport sciences ,General Medicine ,End-stage osteoarthriti ,new design prosthesis ,Surgery ,Radiological weapon ,Medicine ,Anterior approach ,business ,Range of motion - Abstract
Recently, the progress in techniques and in projecting new prosthetic designs has allowed increasing indications for total ankle replacement (TAR) as treatment for ankle osteoarthritis. This retrospective work comprehended 39 subjects aged between 47 and 79 years old. The patients, observed for at least 12 months (mean follow up of 18.2 ± 4.1 months), have been evaluated according to clinical and radiological parameters, both pre- and post-operatively. The AOFAS and VAS score significantly improved, respectively, from 46.2 ± 4.8 to 93.9 ± 4.1 and from 7.1 ± 1.1 to 0.7 ± 0.5 (p value <, 0.05). At the final evaluation, the mean plantarflexion passed from 12.2° ± 2.3° to 18.1° ± 2.4° (p value <, 0.05) and dorsiflexion from a pre-operative mean value of 8.7° ± 4.1° to 21.7° ± 5.4° post-operatively (p value <, 0.05). This study found that this new total ankle replacement design is a safe and effective procedure for patients effected by end-stage ankle osteoarthritis. Improvements have been demonstrated in terms of range of motion, radiographic parameters and patient-reported outcomes. However, further studies are needed to assess the long-term performance of these prostheses.
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- 2021
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18. Piezoelectric tools versus traditional oscillating saw for distal linear osteotomy in hallux valgus correction: Triple-blinded, randomized controlled study
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Massimiliano Mosca, Emanuele Vocale, Mario Fuiano, Davide Censoni, Alessandro Russo, Simone Massimi, Silvio Caravelli, Alberto Grassi, Stefano Zaffagnini, Mosca M., Russo A., Caravelli S., Massimi S., Vocale E., Grassi A., Censoni D., Fuiano M., and Zaffagnini S.
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First metatarsal bone ,Radiography ,medicine.medical_treatment ,Bone healing ,Osteotomy ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,medicine ,Humans ,Orthopedics and Sports Medicine ,Piezosurgery ,Hallux Valgus ,Hallux valgu ,Traditional saw ,Reduction (orthopedic surgery) ,Metatarsal Bones ,Piezoelectric surgery ,Orthodontics ,030222 orthopedics ,biology ,business.industry ,030229 sport sciences ,biology.organism_classification ,Prospective ,Valgus ,medicine.anatomical_structure ,Treatment Outcome ,Distal linear osteotomy ,business - Abstract
Background The main goal of the surgical correction of the hallux valgus is the morphological correction associated with the functional rebalancing of the first ray. The aim of this triple-blinded, randomized controlled study was to show the efficacy of piezosurgery in performing distal linear osteotomy of the first metatarsal bone in HV correction, in terms of clinical and radiological outcomes at 1-year final follow up. Methods and materials This study was performed collecting prospectively pre-operative and post-operative data for all patients. 34 patients were included in the trial and were randomly allocated (1:1) in a Piezoelectric Group (PG) that involved the use of piezoelectric tools and in a Control Group (CG) that provided for the use of a traditional oscillating saw. In both groups, all patients were treated with a distal linear osteotomy of the first metatarsal bone. Clinical and radiographic assessments were performed. Results The AOFAS score between the two groups was similar pre-operatively and during the follow-up period, with a slight superiority in the PG at each evaluation. The osteotomy surgical time was registered for both groups. Among the endpoints of the study, the radiological bone healing time was independently assessed by a radiologist that reported a lower mean value in the piezoelectric group compared with the control group. Conclusions This trial has shown that piezoelectric surgery is not inferior to traditional methods from the clinical-functional point of view, but can even lead to an evident reduction of bone healing time with a statistical significance. Level of evidence Level I.
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- 2021
19. Clinical-radiological outcomes and complications after total ankle replacement through a lateral transfibular approach: a retrospective evaluation at a mid-term follow-up
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Emanuele Vocale, Massimiliano Mosca, Mario Fuiano, Alberto Grassi, Simone Massimi, Nicolò Maitan, Stefano Zaffagnini, Silvio Caravelli, Mosca M., Caravelli S., Vocale E., Maitan N., Grassi A., Massimi S., Fuiano M., and Zaffagnini S.
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medicine.medical_specialty ,medicine.medical_treatment ,Ankle replacement ,Osteoarthritis ,03 medical and health sciences ,Arthroplasty, Replacement, Ankle ,0302 clinical medicine ,Quality of life ,Arthropathy ,medicine ,Humans ,Orthopedics and Sports Medicine ,Range of Motion, Articular ,Aged ,Retrospective Studies ,030203 arthritis & rheumatology ,030222 orthopedics ,business.industry ,Ankle arthroplasty ,Total ankle replacement ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Surgery ,Lateral approach ,medicine.anatomical_structure ,Treatment Outcome ,Orthopedic surgery ,Quality of Life ,Osteoarthriti ,Ankle ,Range of motion ,business ,Trans-fibular ,Ankle Joint ,Follow-Up Studies - Abstract
Purpose: Degenerative ankle arthropathy is a debilitating and increasingly widespread condition with worsening of quality of life. In last years, total ankle replacement has increased indications, thanks to advances in surgical technique, materials and design that provided new solutions for surgeons. The purpose of this study is to evaluate the effectiveness of total ankle replacement (TAR), implanted using a trans-fibular lateral approach in patients with high-grade degenerative arthropathy, in terms of clinical, functional and radiological outcomes and possible complications. Methods: This retrospective study included 73 patients, aged between 47 and 79years (mean age 61.7 ± 14.2years), who underwent trans-fibular total ankle arthroplasty. All patients were followed up for at least two years post-operatively with mean follow-up 31.2 ± 8.1months and have been evaluated clinically and radiographically both pre-operatively and post-operatively. Results: Patients demonstrated a significant improvement in average AOFAS score, SF-36 score and VAS scale. Average plantarflexion improved from 9.9° ± 4.2 to 18.4° ± 6.3 and dorsiflexion from pre-operative mean value of 6.8° ± 5.8 to 17.2° ± 3.1 post-operative. Complications recorded in our series were 16 (21.9%), specifically 2 major complications and 14 minor complications. Conclusions: This study found that trans-fibular total ankle replacement is a safe and effective option for patients with ankle osteoarthritis, resulting in improvement of patient-reported outcomes, range of motion, and radiographic parameters. However, further studies are required to determine long-term performance of these implants.
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- 2021
20. Anterior Cruciate Ligament Reconstruction and Lateral Plasty in High-Risk Young Adolescents: Revisions, Subjective Evaluation, and the Role of Surgical Timing on Meniscal Preservation
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Stefano Zaffagnini, Gian Andrea Lucidi, Giacomo Dal Fabbro, Massimiliano Mosca, Luca Macchiarola, Alberto Grassi, Silvio Caravelli, Grassi A., Macchiarola L., Lucidi G.A., Dal Fabbro G., Mosca M., Caravelli S., and Zaffagnini S.
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medicine.medical_specialty ,Anterior cruciate ligament reconstruction ,Anterior cruciate ligament ,medicine.medical_treatment ,Focus Topic: ACL ,Physical Therapy, Sports Therapy and Rehabilitation ,Knee Injuries ,Meniscus (anatomy) ,<16 years old ,Menisci, Tibial ,Young adolescents ,03 medical and health sciences ,early ,0302 clinical medicine ,medicine ,Humans ,Orthopedics and Sports Medicine ,Meniscus ,Retrospective Studies ,030222 orthopedics ,Anterior Cruciate Ligament Reconstruction ,business.industry ,young ,Anterior Cruciate Ligament Injuries ,030229 sport sciences ,musculoskeletal system ,anterior cruciate ligament (ACL) ,Surgery ,Tibial Meniscus Injuries ,failure ,Meniscal injury ,medicine.anatomical_structure ,Acl graft ,adolescent ,meniscu ,business - Abstract
Background: In adolescents, the rate of meniscal injury at the time of anterior cruciate ligament (ACL) reconstruction, the rate of ACL graft revision, and clinical outcomes has not yet been investigated. Hypothesis: In patients younger than 16 years, the rate of meniscal injuries at the time of ACL reconstruction increases with time from injury. The mid-term revision rate and reoperation rate after ACL reconstruction with hamstrings and lateral tenodesis are lower than those reported in literature for isolate ACL reconstruction. Study Design: Case series. Level of Evidence: Level 4. Methods: Patients younger than 16 years who underwent ACL reconstruction with hamstring and lateral tenodesis, with a follow-up ≥2 years were included. The number of meniscal lesions was stratified according to the delay between injury-to-surgery (12 months). All reoperations, Lysholm score, Knee Injury and Osteoarthritis Outcome Score subscales for pain (at rest and during activity), and return to sport were collected. Results: A total of 151 patients (mean age 14.8 ± 1.2 years) were included. Patients undergoing surgery at 12 months (63%) after injury ( P = 0.04). Medial meniscal lesions were more likely to be repaired when surgery was performed Conclusion: Patients younger than 16 years undergoing ACL reconstruction within 3 months from injury had the lowest rate of meniscal injuries. ACL reconstruction with lateral tenodesis had low revision rate (6%) and good or excellent clinical outcomes in 88% of young adolescents. Clinical Relevance: Sport physicians should be aware that adolescent patients undergoing ACL reconstruction within 3 months after injury have the lowest rate of meniscal injuries; the mid-term revision rate of ACL reconstruction with lateral plasty is lower than 10% and the patients’ perceived outcomes are good with almost all patients returning to sport activity.
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- 2021
21. Hallux valgus associated to osteoarthritis: Clinical-radiological outcomes of modified SERI technique at mid- to long-term follow-up. A retrospective analysis
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M Di Ponte, Davide Censoni, Mario Fuiano, Alberto Grassi, Simone Massimi, Silvio Caravelli, Stefano Zaffagnini, Massimiliano Mosca, Francesco Ceccarelli, Emanuele Vocale, Mosca M., Caravelli S., Vocale E., Fuiano M., Massimi S., Di Ponte M., Censoni D., Grassi A., Ceccarelli F., and Zaffagnini S.
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medicine.medical_specialty ,Metatarsal Bone ,Osteoarthritis ,Follow-Up Studie ,03 medical and health sciences ,Hallux rigidus ,0302 clinical medicine ,Retrospective Studie ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Hallux Valgus ,Metatarsal Bones ,Valgus deformity ,Hallux rigidu ,Retrospective Studies ,030222 orthopedics ,biology ,business.industry ,030229 sport sciences ,SERI ,biology.organism_classification ,medicine.disease ,Surgery ,Osteotomy ,Valgus ,Hallux Valgu ,medicine.anatomical_structure ,Treatment Outcome ,Radiological weapon ,Orthopedic surgery ,Quality of Life ,Osteoarthriti ,Metatarsophalangeal ,Ankle ,business ,Foot (unit) ,Human ,Follow-Up Studies - Abstract
Introduction: Treatment of hallux valgus deformity associated with mild or moderate osteoarthritis (OA) is still a topic of debate. In the literature, there are few studies concerning the management of patients affected by this condition. This study aims to report the experience at mid- to long-term results of an original joint-preserving surgical technique. Materials and Methods: Patients affected by mild to moderate hallux valgus deformity and associated to grade 1–2 OA and treated with modified Simple-Effective-Rapid-Inexpensive (SERI) technique from 2008 to 2018 were selected. Inclusion criteria were mild or moderate hallux valgus angle (HVA)
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- 2020
22. Weight bearing versus conventional CT for the measurement of patellar alignment and stability in patients after surgical treatment for patellar recurrent dislocation
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Giulio Maria Marcheggiani Muccioli, Bruna Maccaferri, Maurizio Busacca, Stefano Zaffagnini, Alberto Leardini, Claudio Belvedere, Stefano Durante, Silvio Caravelli, Antonio Moio, Giada Lullini, Lullini G., Belvedere C., Busacca M., Moio A., Leardini A., Caravelli S., Maccaferri B., Durante S., Zaffagnini S., and Marcheggiani Muccioli G.M.
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Adult ,Male ,Supine position ,Time Factors ,Conventional CT ,Time Factor ,Adolescent ,Patellar Dislocation ,Reproducibility of Result ,medicine.disease_cause ,Weight-bearing ,Follow-Up Studie ,Weight-Bearing ,03 medical and health sciences ,Patellofemoral Joint ,Young Adult ,0302 clinical medicine ,Fascia lata ,Retrospective Studie ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,In patient ,Orthopedic Procedures ,Postoperative Period ,Range of Motion, Articular ,Neuroradiology ,Retrospective Studies ,030222 orthopedics ,medicine.diagnostic_test ,Cone-beam CT ,business.industry ,Ultrasound ,Reproducibility of Results ,Interventional radiology ,030229 sport sciences ,General Medicine ,Cone-Beam Computed Tomography ,Patellofemoral instability ,Orthopedic Procedure ,medicine.anatomical_structure ,Musculoskeletal Radiology ,Female ,Tomography ,Nuclear medicine ,business ,Human ,Follow-Up Studies - Abstract
Purpose To compare weight-bearing cone-beam computer tomography (CBCT) and conventional computer tomography (CT)-based measurements of patellofemoral alignment and stability in patients surgically treated for recurrent patellar dislocation. These scans implied respectively single-leg up-right posture, the knee flexed, and lower limb muscles activation, versus supine position with the knee extended. Methods A total of 17 patients (11 males/6 females) after surgical reconstruction with fascia lata allograft for recurrent patellofemoral dislocation were analyzed at 60-month follow-up. Tilt and congruence angles and tibial tuberosity–trochlear groove (TT-TG) offset were measured on images obtained from CBCT and conventional CT scans by three independent and expert radiologists. Paired t tests were performed to compare measurements obtained from the two scans. Inter-rater reliability was assessed using a two-way mixed-effects model intra-class correlation coefficient (ICC). Results Only TT-TG offset was found significantly smaller (p Conclusion In patients surgically treated for recurrent patellar dislocation, TT-TG offset was found overestimated with conventional CT. All measurements of patellofemoral stability and alignment were found more consistent when obtained with weight-bearing CBCT compared to conventional CT.
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- 2020
23. Ankle joint re-balancing in the management of ankle fracture malunion using fibular lengthening: prospective clinical-radiological results at mid-term follow-up
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Emanuele Vocale, Francesco Ceccarelli, Alberto Grassi, Massimiliano Mosca, Stefano Zaffagnini, Mario Fuiano, Simone Massimi, Roberto Buda, Maria Grazia Benedetti, Silvio Caravelli, Mosca M., Buda R., Ceccarelli F., Fuiano M., Vocale E., Massimi S., Benedetti M.G., Grassi A., Caravelli S., and Zaffagnini S.
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musculoskeletal diseases ,Adult ,medicine.medical_specialty ,medicine.medical_treatment ,Arthrodesis ,Articular re-balancing ,Osteotomy ,Ankle Fractures ,Prosthesis ,Trauma ,03 medical and health sciences ,Fracture Fixation, Internal ,0302 clinical medicine ,medicine ,Internal fixation ,Humans ,Orthopedics and Sports Medicine ,Malunion ,Prospective Studies ,Fibula ,Fractures, Malunited ,Retrospective Studies ,030203 arthritis & rheumatology ,Orthodontics ,030222 orthopedics ,business.industry ,Middle Aged ,medicine.disease ,medicine.anatomical_structure ,Treatment Outcome ,Orthopedic surgery ,Fibular lengthening ,Surgery ,Ankle ,business ,Ankle Joint ,Arthriti ,Follow-Up Studies - Abstract
Purpose: An unsatisfactory reduction and internal fixation of an ankle fracture can result in an alteration of the anatomical axes and distribution of the load on the ankle, with consequent development of chronic pain and articular degeneration. The aim of this study is to evaluate the results of the articular re-balancing with realignment and lengthening of the fibula in case of malunited distal fibular fractures. Methods: A review of prospectively collected data was performed for all patients with a diagnosis of malunion of the fibula and underwent ankle joint re-balancing with fibular lengthening. Twenty-three patients, with a mean age of 39.4 ± 13.1years, have been evaluated using radiographic parameters, American Orthopaedic Foot and Ankle Surgeons ankle-hindfoot, Ankle Activity scale, and SF-36 score at six, 12, 24, and 36months post-operatively. Results: All cases treated showed at follow-up the osteotomy healed in good correction of the deformities. Clinical scores showed a clear improvement: final 36-month mean AOFAS was 74.0 ± 8.9 point, final 36-month mean HALASI score was 4.9 ± 0.9 points, 36-month follow-up SF-36 score showed an average score of 73.2 ± 10.7 points. Pre- and post-operative radiographic parameters have been registered and described. Conclusions: The ankle joint is a complex structure, and even minor changes of the structure of this joint can significantly compromise its functionality. Ankle joint re-balancing is an effective surgical procedure in case of fibular malunion. This procedure, in patients carefully selected, could procrastinate more disabling surgical procedure, as arthrodesis or prosthesis.
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- 2020
24. A mid-term follow-up retrospective evaluation of tarsometatarsal joint fracture-dislocations treated by closed reduction and percutaneous K-wires fixation
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Mario Fuiano, Stefano Zaffagnini, Giulio Maria Marcheggiani Muccioli, Tommaso Roberti di Sarsina, Silvio Caravelli, Massimiliano Mosca, Alberto Grassi, Davide Censoni, Mosca M., Fuiano M., Censoni D., Marcheggiani Muccioli G.M., Roberti di Sarsina T., Grassi A., Caravelli S., and Zaffagnini S.
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Tarsometatarsal joints ,Adult ,medicine.medical_specialty ,Percutaneous ,Fracture-dislocation ,Visual analogue scale ,Deep vein ,Arthrodesis ,medicine.medical_treatment ,Joint Dislocations ,K-wires fixation ,Fixation (surgical) ,Fracture Fixation, Internal ,Fractures, Bone ,Lisfranc ,medicine ,Humans ,General Environmental Science ,Retrospective Studies ,business.industry ,Fracture Dislocation ,Middle Aged ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Inclusion and exclusion criteria ,General Earth and Planetary Sciences ,Tarsometatarsal joint ,Percutaneou ,Ankle ,business ,Bone Wires ,Follow-Up Studies - Abstract
Introduction Injuries involving the tarsometatarsal (TMT) joint are relatively uncommon, and the surgical treatment is potentially characterized by a high complications rate. The purpose of this study is to evaluate the results of the treatment of Lisfranc fracture-dislocations treated with closed reduction and percutaneous fixation with K-wires, considering complications and re-intervantion rate. Materials and methods A retrospective review was performed on all patients undergone closed reduction and percutaneous fixation with K-wires of a Lisfranc fracture-dislocation. Patients have been clinically evaluated at last follow up by American Orthopaedic Foot and Ankle Society (AOFAS) midfoot score and Visual Analogue Scale (VAS), as well as by radiograph assessment. Results Following inclusion and exclusion criteria, 15 patients have been included, with a mean age of 48.2 ± 5.6 years. Average follow-up was 3.8 ± 1.8 years (range 1–6). 7 fractures analyzed were classified as type A, 7 as type B (3 were B1, 4 were B2) and 1 as type C1. No case of loss of reduction has been observed at radiographic 1-month follow-up. At last follow-up mean AOFAS midfoot score and VAS score were respectively 82.2 ± 10.4 and 1.5 ± 1.3. Registered complications showed one deep vein thrombosis and 2 cases of complex regional pain syndrome (CRPS). One patient subsequently underwent arthrodesis of the tarsometatarsal joint for post-traumatic arthritis. Conclusions The treatment of the fracture-dislocations of the Lisfranc joint by percutaneous reduction and fixation with K-wire can achieve good clinical outcomes with a low rate of complications and reoperations. Level of Evidence Level IV
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- 2020
25. Evaluation of proprioception and postural control at a minimum 1 year follow-up after ankle capsuloligamentous lateralplasty with Brostrom technique: A cohort study
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Laura Bragonzoni, Maria Grazia Benedetti, Mario Fuiano, Silvio Caravelli, Massimiliano Mosca, Simone Massimi, Giuseppe Catanese, Giuseppe Barone, Mosca M., Caravelli S., Massimi S., Fuiano M., Catanese G., Barone G., Bragonzoni L., and Benedetti M.G.
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Adult ,Joint Instability ,Male ,Reconstructive surgery ,medicine.medical_specialty ,Brostrom ,medicine.medical_treatment ,proprioception ,Observational Study ,Physical examination ,Follow-Up Studie ,Broström procedure ,ankle sprain ,03 medical and health sciences ,Arthroscopy ,0302 clinical medicine ,Physical medicine and rehabilitation ,Ankle Injurie ,Chronic Ankle Instability ,medicine ,Postural Balance ,Humans ,Orthopedic Procedures ,030212 general & internal medicine ,Ankle Injuries ,Proprioception ,medicine.diagnostic_test ,business.industry ,General Medicine ,Middle Aged ,Orthopedic Procedure ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Orthopedic surgery ,Chronic Disease ,Ligaments, Articular ,Female ,Ankle ,business ,Research Article ,Follow-Up Studies ,Human - Abstract
Recovery of postural control and proprioception in patients affected by chronic ankle instability (CAI) and operated on capsulo-ligaments reconstructive surgery lacks of objective assessment. The aim of this study was to evaluate long-term post-surgical postural and proprioceptive control through the DPPS device in a cohort of patients operated on ligaments reconstruction through the modified Brostrom procedure at a minimum follow up of 12 months. Eleven patients with post-traumatic lateral CAI, operated of external capsulo-ligamentous complex repair according to Brostrom technique at a minimum follow-up of 1 year were enrolled. Physical examination and American Orthopaedics Foot and Ankle Society (AOFAS) ankle-hindfoot score. Proprioceptive and postural stability was assessed by DPPS - Delos Postural Proprioceptive System, linked to a computer with a specific software and including a flat table, an electronic unstable proprioceptive board, a Delos Vertical Controller, a monitor and a horizontal bar fitted with an infra-red sensor for hand support. Patients were 5 males and 6 females, mean age of 38.4 ± 12 years. Mean BMI of the patients was 26.8 ± 4.4. Mean follow up was 13.4 ± 2.1. The mean value of (AOFAS) clinical score was 90.3/100. Mean Static Stability Index (SSI) with open eyes was 87.7% (±7.6) in the operated leg and 90.4% (±6.1) in the contra-lateral. SSI with closed eyes was 64.5% (±11.2) in the operated leg and 61.6% (±16.8) in the contra-lateral. Mean Dynamic Stability Index (DSI) without restrictions was 56.2% (±14.6) in the operated leg and 56.8% (±10.6) in the contra-lateral. DSI with restricted upper limbs, had a mean value of 56.3% (±11.4) in the operated leg and 58.1% (±11.9) in the contra-lateral. Re-tensioning capsular-ligamentous surgery of the external compartment for CAI allow to recovery proprioceptive and postural control on the operated side, comparable with data from the contralateral limb and from the healthy population of the same age and sex.
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- 2020
26. Outcome After Modified Grice-Green Procedure (SAMBB) for Arthritic Acquired Adult Flatfoot
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Massimiliano Mosca, Mario Fuiano, Francesco Ceccarelli, Silvio Caravelli, Stefano Zaffagnini, Alberto Grassi, Emanuele Vocale, Simone Massimi, Mosca M., Caravelli S., Vocale E., Massimi S., Fuiano M., Grassi A., Ceccarelli F., and Zaffagnini S.
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Male ,medicine.medical_specialty ,bone graft ,Subtalar arthrodesis ,Arthrodesis ,SAMBB ,Outcome (game theory) ,Young Adult ,flatfoot ,Surveys and Questionnaires ,biology.animal ,Osteoarthritis ,medicine ,Humans ,Orthopedics and Sports Medicine ,Aged ,Retrospective Studies ,Aged, 80 and over ,biology ,Foot Deformities, Acquired ,business.industry ,adult ,Subtalar Joint ,Retrospective cohort study ,Middle Aged ,Flatfoot deformity ,Surgery ,Radiography ,subtalar arthrodesis ,Grice ,Female ,business - Abstract
Background:Adult acquired flatfoot deformity is a well-known and recognized cause of pain and disability. The purpose of this retrospective study was to describe radiographic and clinical outcomes of the modified mini bone block distraction subtalar arthrodesis (SAMBB) in adult patients affected by adult flatfoot with subtalar joint osteoarthritis at a midterm mean follow-up.Methods:A retrospective review of our database identified patients. Radiological imaging was used to evaluate angular corrections (Meary’s angle [MA], talar coverage angle [TC], and calcaneal pitch angle [CP]) to assess the rate of union and highlight the possible progression of arthritis in nearby joints. Clinical evaluation was performed at the time of surgery and at the final follow-up using the American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot score. Sixty-two feet were evaluated at a mean follow-up of 6.2 ± 4.2 years.Results:The AOFAS score improved from a mean value of 48.1 ± 6.1 to a postoperative average score of 87.7 ± 5. CP, TC, and MA showed a postoperative improvement to 17.7 ± 2.1, 2.9 ± 0.7, and 0.6 ± 0.6 degrees, respectively, at the final follow-up, and all deformities were corrected. Five complications (8%) were reported: 1 major and 4 minor. No graft reabsorption, sural nerve neuralgia, or donor site morbidity was recorded.Conclusion:To our knowledge, this study is the first report of a modified Grice-Green technique (SAMBB) that is a safe and effective treatment of flatfoot in the adult with subtalar arthritis.Level of evidence:Level IV, retrospective case series.
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- 2020
27. A comprehensive and narrative review of historical aspects and management of low-grade hallux rigidus: conservative and surgical possibilities
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S. Massimi, Silvio Caravelli, Massimiliano Mosca, G. Catanese, A. Russo, M. Fuiano, Camilla Pungetti, Stefano Zaffagnini, Caravelli S., Mosca M., Massimi S., Pungetti C., Russo A., Fuiano M., Catanese G., and Zaffagnini S.
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Cartilage, Articular ,Limitu ,medicine.medical_specialty ,Anti-Inflammatory Agents ,Osteogenesis, Distraction ,Complex disease ,Conservative Treatment ,Severity of Illness Index ,03 medical and health sciences ,Hallux rigidus ,0302 clinical medicine ,Hallux Rigidus ,medicine ,Humans ,Orthopedics and Sports Medicine ,Conservative ,Hallux Rigidu ,Surgical treatment ,030222 orthopedics ,Historical ,Articular surfaces ,business.industry ,Sesamoid Bone ,General surgery ,Osteophyte ,Disease Management ,030229 sport sciences ,medicine.disease ,Combined Modality Therapy ,Operative ,Osteotomy ,Surgery ,Anti-Inflammatory Agent ,Orthopedic surgery ,Narrative review ,Sesamoid Bones ,business ,Human - Abstract
Hallux rigidus, Latin for Stiff Toe, is characterized by an osteoarthritic degeneration of the articular surfaces of the first metatarsophalangeal joint. The aim of this literature narrative overview is to summarize and expose the great amount of management concepts and information, including the well-codified operative procedures and the more up to date knowledge about non-operative and surgical treatment of hallux rigidus. This may provide current information for physicians, medschool attendants and researchers. A comprehensive literature search using PubMed database has been performed, up to April 1, 2017. Several different types of treatment are described in the literature for low-grade hallux rigidus. The management for hallux rigidus can involve a variety of therapeutic interventions, conservative or operative. Hallux rigidus is a complex disease characterized by several clinical and pathological findings, and to achieve optimal results, surgical treatment for low-grade forms should be chosen between several surgical techniques depending on the degree of arthritis and other different clinical conditions.
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- 2018
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28. Interposition Arthroplasty in the Treatment of End-Stage Hallux Rigidus: A Systematic Review
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Marco Di Ponte, Silvio Caravelli, Massimiliano Mosca, Stefano Zaffagnini, Francesco Di Caprio, Francesco Ceccarelli, Lorenzo Ponziani, Di Caprio F., Mosca M., Ceccarelli F., Caravelli S., Di Ponte M., Zaffagnini S., and Ponziani L.
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diagnostic and therapeutic technique ,Moderate to severe ,medicine.medical_specialty ,business.industry ,Arthrodesis ,medicine.medical_treatment ,Interposition arthroplasty ,big toe joint pain ,medicine.disease ,Surgery ,Hallux rigidus ,implant arthroplasty ,hallux limitu ,forefoot—toe—midfoot ,medicine ,arthritis and joint disease ,Orthopedics and Sports Medicine ,Hallux Limitus ,Podiatry ,Stage (cooking) ,comorbid condition ,business - Abstract
Purpose Patients affected by moderate to severe hallux rigidus may opt for interposition arthroplasty to avoid the movement restrictions of arthrodesis and the complications related to prosthetic replacement. The propose of this article was to review the current literature about interposition arthroplasty to examine the overall outcomes and to evaluate the advantages and disadvantages of different types of technique, compared with more consolidated procedures. Methods A literature PubMed search was performed. Studies reporting the results of interposition arthroplasty in moderate to severe hallux rigidus were included. The data were pooled and weighted for number of patients in every study. Results The overall results for interposition arthroplasties are comparable to other alternatives for end-stage hallux rigidus, providing better plantar load distribution than arthrodesis and avoiding the drawbacks of prosthetic replacement. Among the various interposition arthroplasty techniques, the Modified Oblique Keller Capsular Interposition Arthroplasty technique preserves toe length and flexor hallucis brevis function, showing the highest satisfaction rate, with lowest metatarsalgia and revision rate. Conclusion Although long-term randomized controlled trials are lacking for interposition arthroplasty, it represents a valid alternative for the treatment of end-stage hallux rigidus also in the young active patient who wants to avoid a definitive intervention immediately. Level of evidence III (systematic review of level III-IV-V studies)
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- 2021
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29. A novel method for internal fixation of basal fifth metatarsal fracture in athletes: a cadaveric study of the F.E.R.I. technique (Fifth metatarsal, Extra-portal, Rigid, Innovative)
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Silvio Caravelli, Simone Massimi, James D. F. Calder, Pieter D’Hooghe, Stefano Zaffagnini, Peter Dzendrowskyj, D'Hooghe P., Caravelli S., Massimi S., Calder J., Dzendrowskyj P., and Zaffagnini S.
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Orthodontics ,Stress fractures ,business.industry ,Research ,medicine.medical_treatment ,Tension band wiring ,Internal fixation ,medicine.disease ,Fifth metatarsal ,law.invention ,Intramedullary rod ,lcsh:RD701-811 ,Fixation (surgical) ,Fracture ,lcsh:Orthopedic surgery ,Athlete ,law ,Cadaver ,medicine ,Orthopedics and Sports Medicine ,Kirschner wire ,Cadaveric spasm ,business - Abstract
PurposeOne of the main problems of Kirschner wire fixation of fifth metatarsal base fractures (in combination with a tension band wiring technique) seems to be hardware intolerance and several studies in athletes also report failure after isolated fixation with a screw only. These reports prompted us to look at new materials and a novel technique through fixation with an intramedullary screw combined with a high-resistance suture via the presented F.E.R.I. (Fifth metatarsal, Extra-portal, Rigid, Innovative) technique.MethodsThis cadaveric study describes F.E.R.I. technique. On a cadaver, through two mini portals, a full reduction and solid internal fixation with an intramedullary screw and suture cerclage with Fiberwire of a fifth metatarsal base fracture is achieved. In this article, the cadaveric study and proposed surgical technique are explained and illustrated step by step.ResultsThe presented internal fixation F.E.R.I. technique is indicated in acute proximal fractures, stress fractures or non-union of metatarsal 5 (Zone 2–3 by Lawrence and Botte) and it resulted feasible and stable during manual stress test. The authors intend to study this technique in the clinical setting in the near future.ConclusionsFifth metatarsal base fractures gain specific interest when occurring in athletes. In this group of patients, internal fixation is often required to obtain a satisfactory outcome and time to return to play. The aim of the presented cadaveric study is to illustrate an innovative concept of internal fixation, named F.E.R.I.
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- 2019
30. Return to Sports after Unicompartmental Knee Arthroplasty: Reality or Utopia? A 48-Month Follow-Up Prospective Study
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Stefano Zaffagnini, Giulio Maria Marcheggiani Muccioli, Sergio Cialdella, Giuseppe Agrò, Alberto Grassi, Massimiliano Mosca, Mirco Lo Presti, Silvio Caravelli, Giuseppe Gianluca Costa, and Lo Presti M, Costa GG, Cialdella S, Agrò G, Grassi A, Caravelli S, Mosca M, Marcheggiani Muccioli GM, Zaffagnini S.
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musculoskeletal diseases ,Male ,medicine.medical_specialty ,Visual Analog Scale ,Visual analogue scale ,medicine.medical_treatment ,Football ,Osteoarthritis ,03 medical and health sciences ,0302 clinical medicine ,medial UKA - physical activity - unicompartmental knee arthroplasty - sport ,medicine ,Humans ,Orthopedics and Sports Medicine ,Prospective Studies ,Unicompartmental knee arthroplasty ,Prospective cohort study ,Arthroplasty, Replacement, Knee ,Aged ,030222 orthopedics ,business.industry ,030229 sport sciences ,Middle Aged ,Osteoarthritis, Knee ,medicine.disease ,Arthroplasty ,Return to Sport ,Physical therapy ,Surgery ,Female ,business ,human activities ,Body mass index ,Month follow up ,Follow-Up Studies - Abstract
Unicompartmental knee arthroplasty (UKA) has increased in popularity in the last years, also in younger and more active patients with great expectancies. The purpose of our study was to investigate the change in sports activities before and after medial UKA. We surveyed 53 athletic patients; all underwent cemented medial UKA, to determine not only their subjective and objective evaluation of clinical status with Hospital for Special Surgery (HSS) and visual analog score (VAS) score, but also their sporting and recreational activities at a mean follow-up of 48 ± 6 months (range, 18–56 months). At the last follow-up, 48 of 53 patients were engaged in sports and recreational disciplines, resulting in a return to activity rate of 90%. No early failure and no cases of revision were reported. The frequency of activities (sessions per week) and the time session remained constant at the time of survey. The most common activities after surgery were hiking, cycling, and swimming. Several high-impact activities, as well as skiing and football, had a significant decrease in participating patients. There were no gender-, age- and body mass index (BMI)-related differences. UKA can be considered a viable alternative in relatively young patients with high functional requirements and the correct indications, however, warning the patients about the risks of polyethylene wear and early loosening of the prosthetic components as a result of the resumption of sporting activities in high impact. Level of Evidence Prospective case series, level 4.
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- 2018
31. Percutaneous treatment of hallux valgus: What's the evidence? A systematic review
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S. Massimi, M. Fuiano, M. Lo Presti, Silvio Caravelli, Stefano Zaffagnini, Giuseppe Gianluca Costa, Massimiliano Mosca, Alberto Grassi, Caravelli, S, Mosca, M, Massimi, S, Costa, G G, Lo Presti, M, Fuiano, M, Grassi, A, and Zaffagnini, S
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medicine.medical_specialty ,Weakness ,Percutaneous ,medicine.medical_treatment ,Osteotomy ,Burr ,Severity of Illness Index ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Multicenter Studies as Topic ,Orthopedics and Sports Medicine ,Hallux Valgus ,Hallux valgu ,Randomized Controlled Trials as Topic ,Aofas score ,030222 orthopedics ,biology ,Distal osteotomy ,business.industry ,030229 sport sciences ,biology.organism_classification ,Surgery ,Valgus ,medicine.anatomical_structure ,Treatment Outcome ,Orthopedic surgery ,Ankle ,medicine.symptom ,business ,Systematic search ,Follow-Up Studies - Abstract
Hallux and first MTP joint have a fundamental role in the transfer of the weight-bearing load during the normal ambulation. The aim of this paper is to review and analyze the available literature about the percutaneous surgical management of the hallux valgus to highlight its strengths and weakness, also comparing with other minimal invasive techniques. A systematic search of PubMed and Google Scholar databases has been performed, covering the period between 1981 and 2016. Various combinations of the keyword terms "PDO," "hallux valgus," "bunion," "percutaneous," "surgery," "non-invasive," "minimal invasive," "burr," "osteotomy," "distal," "linear," "saw" have been used.Four papers, published from 2005 to 2015, fulfilled the inclusion criteria. A total of 464 hallux valgus has been treated with a properly percutaneous distal first metatarsal osteotomy. Mean AOFAS score, retrieved from the 4 studies included in our review, has been recorded. There are different aspects that the foot and ankle non-experienced surgeon has to consider about percutaneous surgery: limitation of the tools, radioexposure, lack of direct visual control of the osteotomy and higher costs and patient risk due to surgical time.
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- 2017
32. Correlation between tooth decay and insulin resistance in normal weight males prompts a role for myo-inositol as a regenerative factor in dentistry and oral surgery: a feasibility study.
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Barbaro F, Conza GD, Quartulli FP, Quarantini E, Quarantini M, Zini N, Fabbri C, Mosca S, Caravelli S, Mosca M, Vescovi P, Sprio S, Tampieri A, and Toni R
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Background: In an era of precision and stratified medicine, homogeneity in population-based cohorts, stringent causative entry, and pattern analysis of datasets are key elements to investigate medical treatments. Adhering to these principles, we collected in vivo and in vitro data pointing to an insulin-sensitizing/insulin-mimetic effect of myo-inositol (MYO) relevant to cell regeneration in dentistry and oral surgery. Confirmation of this possibility was obtained by in silico analysis of the relation between in vivo and in vitro results (the so-called bed-to-benchside reverse translational approach)., Results: Fourteen subjects over the 266 screened were young adult, normal weight, euglycemic, sedentary males having normal appetite, free diet, with a regular three-times-a-day eating schedule, standard dental hygiene, and negligible malocclusion/enamel defects. Occlusal caries were detected by fluorescence videoscanning, whereas body composition and energy balance were estimated with plicometry, predictive equations, and handgrip. Statistically significant correlations (Pearson r coefficient) were found between the number of occlusal caries and anthropometric indexes predicting insulin resistance (IR) in relation to the abdominal/visceral fat mass, fat-free mass, muscular strength, and energy expenditure adjusted to the fat and muscle stores. This indicated a role for IR in affecting dentin reparative processes. Consistently, in vitro administration of MYO to HUVEC and Swiss NIH3T3 cells in concentrations corresponding to those administered in vivo to reduce IR resulted in statistically significant cell replication (ANOVA/Turkey tests), suggesting that MYO has the potential to counteract inhibitory effects of IR on dental vascular and stromal cells turnover. Finally, in in silico experiments, quantitative evaluation (WOE and information value) of a bioinformatic Clinical Outcome Pathway confirmed that in vitro trophic effects of MYO could be transferred in vivo with high predictability, providing robust credence of its efficacy for oral health., Conclusion: Our reverse bed-to-benchside data indicate that MYO might antagonize the detrimental effects of IR on tooth decay. This provides feasibility for clinical studies on MYO as a regenerative factor in dentistry and oral surgery, including dysmetabolic/aging conditions, bone reconstruction in oral destructive/necrotic disorders, dental implants, and for empowering the efficacy of a number of tissue engineering methodologies in dentistry and oral surgery., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Barbaro, Conza, Quartulli, Quarantini, Quarantini, Zini, Fabbri, Mosca, Caravelli, Mosca, Vescovi, Sprio, Tampieri and Toni.)
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- 2024
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33. An Intraoperative Method to Minimize Leg Length Discrepancy in Anterior Minimally Invasive Total Hip Arthroplasty-A Prospective Study.
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Girolami M, Bevoni R, Artioli E, Beluzzi R, Vasco C, Caravelli S, Baiardi A, and Mosca M
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While several intraoperative devices have been described in the literature for assessing leg length discrepancy (LLD), none have been utilized during total hip arthroplasty (THA) performed via the Anterior Minimally Invasive Surgery (AMIS) approach. The aim of this prospective study was to evaluate the efficacy and accuracy of a compass device in assessing leg length during THA performed using the AMIS technique. A prospective study was conducted involving 35 patients who consecutively underwent unilateral primary THA using the AMIS technique at our department from September 2017 to December 2018. LLD was measured by comparing preoperative and postoperative anteroposterior radiographs of the pelvis, independently assessed by two observers. The mean preoperative LLD was 3.6 (SD 3.9, range, 0.2-19.3) mm. The mean postoperative LLD was 2.5 (SD 3.0, range, 0-12.2) mm. A postoperative LLD of less than 5 mm was observed in 88.2% of cases, with 94.1% having values less than 10 mm. In conclusion, the compass device emerged as a valuable tool for ensuring precise limb length control in THA with the AMIS approach, offering both efficiency and cost-effectiveness in clinical practice.
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- 2024
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34. From Diagnosis to Decision-Making: A Systematic Review of the Management of Reverse Hill-Sachs Lesions after Posterior Shoulder Dislocations.
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Rinaldi VG, Coliva F, Favero A, Alesi D, Caravelli S, Zaffagnini S, and Marcheggiani Muccioli GM
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(1) Background : The aim of this study is to describe all of the possible surgical procedures that intend to treat the McLaughlin lesion (or Reverse Hill-Sachs) in posterior shoulder dislocation. (2) Methods : Google Scholar, Pubmed, and Embase were used as databases in our research. Studies reporting the results of posterior shoulder dislocations surgically treated with procedures addressing the humeral lesion were evaluated. The studies reporting results after fracture-dislocation and multidirectional instability were excluded. (3) Results : A total of 16 studies were included in our review for a total of 207 shoulders with a mean age of 41.7 years that were evaluated at a mean of 62.1 months. The Modified McLaughlin procedure and the Graft procedures were the most commonly performed. No statistically significant difference was found between the two at the evaluation of the clinical score. (4) Conclusions : Our review highlights the importance of a correct diagnosis and an accurate surgical treatment choice based on the surgeon's experience and on the patients' characteristics.
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- 2024
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35. In Vivo Total Ankle Arthroplasty Kinematic Evaluation: A Prospective Radiostereometric Analysis.
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Caravelli S, Bragonzoni L, Zinno R, Vocale E, Pinelli E, Barone G, Vara G, Di Paolo S, Zaffagnini S, and Mosca M
- Abstract
Ankle osteoarthritis (OA) represents a significant social burden and is one of the main causes of chronic disability in a rapidly growing part of the world's population. Total ankle arthroplasty (TAA) has become increasingly popular despite the poor results obtained with the first dedicated designs. The purpose of this paper was to evaluate the ankle kinematics, in vivo and under weight-bearing conditions, of a TAA through a dynamic model-based radiostereometric analysis (MB-RSA). The clinical evaluation was performed by administering the American Orthopaedic Foot and Ankle Society ankle-hindfoot score and Short Form-36 questionnaires. The kinematic evaluation was conducted through MB-RSA during the execution of an open kinetic chain and a closed kinetic chain motor task. Double radiographic images of the ankle joint were processed using dedicated software to obtain a 3D reconstruction of the ankle prosthetic components' motion. Eighteen patients (five females) completed the clinical and instrumental preoperative and postoperative evaluations (age 59.1 ± 10.3). All clinical scores showed a marked improvement ( p < 0.005). During the closed kinetic chain motor tasks, the ankle showed a total range of motion (ROM) in dorsi-plantarflexion of 19.84°. The parameters in varus-valgus were recorded. Physiological motion can be achieved in TAA, characterized by a wide range of motion and coupling of movements on the three planes. The results of the present work may help to understand the real movement of a widespread TAA model and possibly to improve future designs and instrumentation.
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- 2024
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36. Tibiotalocalcaneal arthrodesis in a rare case of tuberculosis of the talus.
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Comisi C, Greco T, Inverso M, Mascio A, Polichetti C, Barbaliscia M, La Vergata V, Mosca M, Caravelli S, Mondanelli N, Troiano E, Maccauro G, and Perisano C
- Abstract
Aim To assess our personal experience of a case of tuberculosis of the talus, and to provide an overview of the literature about the tuberculosis manifestations, including all its aspects: epidemiology, clinical and imaging presentation, and all the treatments available to the current state of knowledge. Methods We present our experience in a case of a 34-year-old patient, who came to our attention with difficulty in walking and pain due to a talar tuberculosis, with consequent bone disruption and reabsorption, and foot deformities. Results A tibiotalocalcaneal arthrodesis with retrograde nail and bone graft was performed after antibiotic therapy. Today, almost two years after the treatment, the patient can walk independently with no major limitations in everyday life. Conclusion Tibiotalocalcaneal arthrodesis with bone graft showed good functional results in this case study, with complete graft fusion and good functional and radiological outcomes., (Copyright© by the Medical Assotiation of Zenica-Doboj Canton.)
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- 2024
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37. Fugitive Acromegaly: A Historical, Clinical, and Translational Perspective.
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Toni R, Barbaro F, Di Conza G, Elviri L, Mosca S, Caravelli S, Mosca M, Arkun K, Asa SL, and Lechan RM
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- Humans, Animals, Pituitary Neoplasms metabolism, Pituitary Neoplasms history, Pituitary Neoplasms diagnosis, Human Growth Hormone metabolism, History, 20th Century, Translational Research, Biomedical methods, Acromegaly metabolism, Acromegaly history
- Abstract
The term 'fugitive acromegaly' was introduced by the neurosurgeons Bailey and Cushing in 1928 to describe subjects manifesting signs and symptoms of somatotroph hyperfunction with pituitary insufficiency. Currently, it identifies patients with subtle acromegalic dysmorphisms and inconsistent hormonal profile, possibly presenting only with hyperprolactinemia and related clinical symptoms. Patients have rapidly growing, locally invasive, relapsing pituitary macrotumors that can be classified as either acidophil stem cell tumors (ASCTs) or sparsely granulated somatotroph tumors (SGSTs), both of PIT1-lineage. ASCTs also express estrogen receptor (ER)α, show predominant prolactin (PRL) release, and less abundantly, growth hormone (GH). In contrast, SGSTs have moderately increased GH and IGF1 levels, but rarely PRL increase. ASCTs often present resistance to dopamine agonists, and long-acting somatostatin analogs are used. In contrast, SGSTs are often resistant to somatostatin analogues and instead are treated with the GH receptor antagonist pegvisomant. Differential diagnosis includes mammosomatotroph, mixed GH-/PRL-secreting, immature PIT1-lineage, and densely granulated somatotroph tumors. Studies in ER-sensitive rat tumoral mammosomatotroph cells (GH3, GH4C1) suggest that overexpression of chaperones in immature PIT1-/ER-expressing progenitors induces posttranscriptional conformational changes to tumor suppressors of the ERα and aryl hydrocarbon receptor pathways, like AIP, leading to the development of aggressive pituitary tumors like those causing fugitive acromegaly., (© 2024 S. Karger AG, Basel.)
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- 2024
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38. A bioartificial and vasculomorphic bone matrix-based organoid mimicking microanatomy of flat and short bones.
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Toni R, Barbaro F, Di Conza G, Zini N, Remaggi G, Elviri L, Spaletta G, Quarantini E, Quarantini M, Mosca S, Caravelli S, Mosca M, Ravanetti F, Sprio S, and Tampieri A
- Subjects
- Adult, Male, Rats, Animals, Humans, Mice, Tissue Scaffolds, Cell Differentiation, Fibroblasts, Extracellular Matrix, Collagen, Osteogenesis, Organoids, Biocompatible Materials, Cells, Cultured, Tissue Engineering, Mammals, Bone Matrix, Osteoporosis
- Abstract
We engineered an in vitro model of bioartificial 3D bone organoid consistent with an anatomical and vascular microenvironment common to mammalian flat and short bones. To achieve this, we chose the decellularized-decalcified matrix of the adult male rat scapula, implemented with the reconstruction of its intrinsic vessels, obtained through an original intravascular perfusion with polylevolactic (PLLA), followed by coating of the PLLA-fabricated vascularization with rat tail collagen. As a result, the 3D bone and vascular geometry of the native bone cortical and cancellous compartments was reproduced, and the rat tail collagen-PLLA biomaterial could in vitro act as a surrogate of the perivascular extracellular matrix (ECM) around the wall of the biomaterial-reconstituted cancellous vessels. As a proof-of-concept of cell compatibility and site-dependent osteoinductive properties of this bioartificial 3D construct, we show that it in vitro leads to a time-dependent microtopographic positioning of rat mesenchymal stromal cells (MSCs), initiating an osteogenic fate in relation to the bone compartment. In addition, coating of PLLA-reconstructed vessels with rat tail collagen favored perivascular attachment and survival of MSC-like cells (mouse embryonic fibroblasts), confirming its potentiality as a perivascular stroma for triggering competence of seeded MSCs. Finally, in vivo radiographic topography of bone lesions in the human jaw and foot tarsus of subjects with primary osteoporosis revealed selective bone cortical versus cancellous involvement, suggesting usefulness of a human 3D bone organoid engineered with the same principles of our rat organoid, to in vitro investigate compartment-dependent activities of human MSC in flat and short bones under experimental osteoporotic challenge. We conclude that our 3D bioartificial construct offers a reliable replica of flat and short bones microanatomy, and promises to help in building a compartment-dependent mechanistic perspective of bone remodeling, including the microtopographic dysregulation of osteoporosis., (© 2023 The Authors. Journal of Biomedical Materials Research Part B: Applied Biomaterials published by Wiley Periodicals LLC.)
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- 2024
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39. Interposition Arthroplasty in the Treatment of End-Stage Hallux Rigidus: A Systematic Review.
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Di Caprio F, Mosca M, Ceccarelli F, Caravelli S, Di Ponte M, Zaffagnini S, and Ponziani L
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- Humans, Treatment Outcome, Arthroplasty methods, Foot surgery, Hallux Rigidus surgery, Metatarsophalangeal Joint surgery
- Abstract
Purpose: Patients affected by moderate to severe hallux rigidus may opt for interposition arthroplasty to avoid the movement restrictions of arthrodesis and the complications related to prosthetic replacement. The propose of this article was to review the current literature about interposition arthroplasty to examine the overall outcomes and to evaluate the advantages and disadvantages of different types of technique, compared with more consolidated procedures., Methods: A literature PubMed search was performed. Studies reporting the results of interposition arthroplasty in moderate to severe hallux rigidus were included. The data were pooled and weighted for number of patients in every study., Results: The overall results for interposition arthroplasties are comparable to other alternatives for end-stage hallux rigidus, providing better plantar load distribution than arthrodesis and avoiding the drawbacks of prosthetic replacement. Among the various interposition arthroplasty techniques, the Modified Oblique Keller Capsular Interposition Arthroplasty technique preserves toe length and flexor hallucis brevis function, showing the highest satisfaction rate, with lowest metatarsalgia and revision rate., Conclusion: Although long-term randomized controlled trials are lacking for interposition arthroplasty, it represents a valid alternative for the treatment of end-stage hallux rigidus also in the young active patient who wants to avoid a definitive intervention immediately., Level of Evidence: III (systematic review of level III-IV-V studies)., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2023
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40. Proprioception and Mechanoreceptors in Osteoarthritis: A Systematic Literature Review.
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Salamanna F, Caravelli S, Marchese L, Carniato M, Vocale E, Gardini G, Puccetti G, Mosca M, and Giavaresi G
- Abstract
Purpose: Osteoarthritis (OA) is one of the most common chronic diseases in the world. It is frequently accompanied by high levels of persistent pain, as well as substantial impairments in function and functional capacity. This review aims to systematically analyze the changes in proprioception and related mechanoreceptors in OA patients., Methods: Studies from September 2013 to September 2023 were identified by conducting searches on the PubMed, Web of Science, and Scopus electronic databases following the PRISMA statement. One reviewer independently assessed and screened the literature, extracted the data, and graded the studies. The body of evidence underwent an evaluation and grading process using the ROBINS-I tool, which was specifically designed to assess the risk of bias in non-randomized studies of interventions. Results were summarized using descriptive methods., Results: A search through 37 studies yielded 14 clinical studies that were ultimately included. The primary focus of the studies was on the knee joint, particularly the posterior cruciate ligament (PCL). The studies found that PCL in OA patients had impaired proprioceptive accuracy, possibly due to changes in mechanoreceptors (Ruffini, Pacini, and Golgi Mazzoni corpuscles). This suggests that dysfunctional articular mechanoreceptors, especially in severe cases of OA, may contribute to reduced proprioception. Dynamic stabilometry also identified significant proprioceptive deficits in patients with knee articular cartilage lesions, underscoring the impact of such lesions on knee proprioception., Conclusions: Literature data have shown that proprioceptive accuracy may play an important role in OA, particularly in the knee PCL and cartilage. However, the role of proprioception and related mechanoreceptors needs to be further clarified. Future studies focusing on the relationship between proprioception, OA disease, and symptoms, considering age and gender differences, and exploring OA joints other than the knee should be conducted to improve clinical and surgical outcomes in cases where proprioception and mechanoreceptors are impaired in OA patients.
- Published
- 2023
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41. Woven bone formation and mineralization by rat mesenchymal stromal cells imply increased expression of the intermediate filament desmin.
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Di Conza G, Barbaro F, Zini N, Spaletta G, Remaggi G, Elviri L, Mosca S, Caravelli S, Mosca M, and Toni R
- Subjects
- Male, Animals, Rats, Osteogenesis, Intermediate Filaments, Core Binding Factor Alpha 1 Subunit, Desmin, Proteomics, Alkaline Phosphatase, Osteitis Deformans, Calcinosis, Mesenchymal Stem Cells, Adenocarcinoma, Bone Diseases, Metabolic
- Abstract
Background: Disordered and hypomineralized woven bone formation by dysfunctional mesenchymal stromal cells (MSCs) characterize delayed fracture healing and endocrine -metabolic bone disorders like fibrous dysplasia and Paget disease of bone. To shed light on molecular players in osteoblast differentiation, woven bone formation, and mineralization by MSCs we looked at the intermediate filament desmin (DES) during the skeletogenic commitment of rat bone marrow MSCs (rBMSCs), where its bone-related action remains elusive., Results: Monolayer cultures of immunophenotypically- and morphologically - characterized, adult male rBMSCs showed co-localization of desmin (DES) with vimentin, F-actin, and runx2 in all cell morphotypes, each contributing to sparse and dense colonies. Proteomic analysis of these cells revealed a topologically-relevant interactome, focused on cytoskeletal and related enzymes//chaperone/signalling molecules linking DES to runx2 and alkaline phosphatase (ALP). Osteogenic differentiation led to mineralized woven bone nodules confined to dense colonies, significantly smaller and more circular with respect to controls. It significantly increased also colony-forming efficiency and the number of DES-immunoreactive dense colonies, and immunostaining of co-localized DES/runx-2 and DES/ALP. These data confirmed pre-osteoblastic and osteoblastic differentiation, woven bone formation, and mineralization, supporting DES as a player in the molecular pathway leading to the osteogenic fate of rBMSCs., Conclusion: Immunocytochemical and morphometric studies coupled with proteomic and bioinformatic analysis support the concept that DES may act as an upstream signal for the skeletogenic commitment of rBMSCs. Thus, we suggest that altered metabolism of osteoblasts, woven bone, and mineralization by dysfunctional BMSCs might early be revealed by changes in DES expression//levels. Non-union fractures and endocrine - metabolic bone disorders like fibrous dysplasia and Paget disease of bone might take advantage of this molecular evidence for their early diagnosis and follow-up., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Di Conza, Barbaro, Zini, Spaletta, Remaggi, Elviri, Mosca, Caravelli, Mosca and Toni.)
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- 2023
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42. Arthroscopic approach does not yield better results than open surgery after subscapularis repair: a systematic review.
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Rinaldi VG, La Verde M, Coliva F, Cammisa E, Lullini G, Caravelli S, Mosca M, Zaffagnini S, and Marcheggiani Muccioli GM
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- Humans, Male, Middle Aged, Female, Rotator Cuff surgery, Arthroscopy methods, Pain, Postoperative, Treatment Outcome, Rotator Cuff Injuries surgery, Tendon Injuries surgery
- Abstract
Purpose: This study aimed to compare the long-term outcomes of arthroscopic versus mini-open repair in patients with isolated subscapularis tendon tears., Methods: Google Scholar, PubMed, and Embase databases were searched for studies evaluating isolated subscapularis tears subsequently treated by arthroscopic or mini-open repair. The inclusion criteria were clinical studies reporting isolated subscapularis lesions treated by arthroscopic or mini-open repair, a minimum follow-up of 12 months, and clinical and functional outcomes reported in the study results. Articles not reporting functional outcomes or studies that reported results for anterosuperior rotator cuff tears without a separate analysis of subscapularis tendon tears were excluded. Studies older than 20 years and studies with a minimum follow-up of less than 12 months were also excluded., Results: A total of 12 studies met the inclusion criteria; 8 papers were included in the arthroscopic repair group, and 6 were included in the mini-open repair group (2 studies reported results for both techniques). The mean age reported was 49.3 years, and 85.1% of patients were male. The dominant limb was involved in 77.6% of the patients, and a traumatic onset of symptoms was verified in 76.3%. The mean time to surgery was 9.6 months. The Constant-Murley score showed positive results for the arthroscopic and mini-open groups, with mean postoperative values of 84.6 and 82.1, respectively. Promising results were also observed for pain, with a mean of 13.2 (out of 15) points for the arthroscopic group and 11.7 for the mini-open group. The long head of the biceps was involved in 78% of the patients, and LHB tenodesis or tenotomy were the most common concomitant procedures performed., Conclusions: There was no significant difference in clinical and functional outcomes between open and arthroscopic repair. Moreover, the same complication rates were reported in both treatments, but arthroscopic repair led to less postoperative pain., Level of Evidence: IV., (© 2023. The Author(s).)
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- 2023
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43. Tibiotalar and Tibiotalocalcaneal Arthrodesis with Paragon28 Silverback TM Plating System in Patients with Severe Ankle and Hindfoot Deformity.
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Perisano C, Cannella A, Polichetti C, Mascio A, Comisi C, De Santis V, Caravelli S, Mosca M, Spedicato GA, Maccauro G, and Greco T
- Subjects
- Humans, Retrospective Studies, Quality of Life, Ankle Joint, Arthrodesis methods, Treatment Outcome, Ankle, Osteoarthritis
- Abstract
Background and Objectives: The treatment of end-stage ankle osteoarthritis (OA) and associated hindfoot deformities remains a major challenge for orthopedic surgeons. Numerous techniques and surgical approaches have been proposed for tibiotalar (TT) and tibiotalocalcaneal (TTC) arthrodesis, from arthroscopic to open, as well as numerous devices proposed for internal fixation (retrograde intramedullary nails, cannulated screws, and plating systems). The aim of this study was to retrospectively analyze the results, with at least 18 months of follow-up, with Silverback
TM TT/TTC Plating System Paragon28 in a group of 20 patients with severe OA and hindfoot deformities (mainly secondary post-traumatic OA)., Materials and Methods: The demographic characteristics and past medical history of the patients were collected and analyzed to identify the cause of the pathology. The degree of OA and deformity were quantified based on foot and ankle weight-bearing radiography and CT examination. Pre- and post-operative clinical and functional scores (ROM, VAS, AOFAS, FFI, and SF-36) and radiographic parameters (anterior distal tibial angle, tibiotalar angle, coronal tibiotalar angle, and hindfoot alignment angle) were evaluated., Results: All of the patients showed clinical and radiographic fusion at an average of 14 weeks (range 12-48), with improvement in pain and functional scores, without major surgical complications and/or infections., Conclusions: Despite the limitations of our study, the results with this new plating system showed good results in terms of bone consolidation, post-operative complications, and improvement of pain and quality of life in patients with severe OA and deformities of the ankle and hindfoot.- Published
- 2023
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44. RANKL-RANK-OPG Pathway in Charcot Diabetic Foot: Pathophysiology and Clinical-Therapeutic Implications.
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Greco T, Mascio A, Comisi C, Polichetti C, Caravelli S, Mosca M, Mondanelli N, Troiano E, Maccauro G, and Perisano C
- Subjects
- Humans, Osteoprotegerin metabolism, Receptor Activator of Nuclear Factor-kappa B, Calcitonin, Denosumab, NF-kappa B, RANK Ligand metabolism, Diabetic Foot drug therapy, Diabetic Foot etiology, Bone Density Conservation Agents therapeutic use, Osteolysis, Diabetes Mellitus
- Abstract
Charcot Foot (CF), part of a broader condition known as Charcot Neuro-Osteoarthropathy (CNO), is characterized by neuropathic arthropathy with a progressive alteration of the foot. CNO is one of the most devastating complications in patients with diabetes mellitus and peripheral neuropathy but can also be caused by neurological or infectious diseases. The pathogenesis is multifactorial; many studies have demonstrated the central role of inflammation and the Receptor Activator of NF-κB ligand (RANKL)-Receptor Activator of NF-κB (RANK)-Osteoprotegerin (OPG) pathway in the acute phase of the disease, resulting in the serum overexpression of RANKL. This overexpression and activation of this signal lead to increased osteoclast activity and osteolysis, which is a prelude to bone destruction. The aim of this narrative review is to analyze this signaling pathway in bone remodeling, and in CF in particular, to highlight its clinical aspects and possible therapeutic implications of targeting drugs at different levels of the pathway. Drugs that act at different levels in this pathway are anti-RANKL monoclonal antibodies (Denosumab), bisphosphonates (BP), and calcitonin. The literature review showed encouraging data on treatment with Denosumab, although in a few studies and in small sample sizes. In contrast, BPs have been re-evaluated in recent years in relation to the high possibility of side effects, while calcitonin has shown little efficacy on CNO.
- Published
- 2023
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45. Adult Acquired Flatfoot Deformity: A Narrative Review about Imaging Findings.
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Polichetti C, Borruto MI, Lauriero F, Caravelli S, Mosca M, Maccauro G, Greco T, and Perisano C
- Abstract
Adult acquired flatfoot deformity (AAFD) is a disorder caused by repetitive overloading, which leads to progressive posterior tibialis tendon (PTT) insufficiency. It mainly affects middle-aged women and occurs with foot pain, malalignment, and loss of function. After clinical examination, imaging plays a key role in the diagnosis and management of this pathology. Imaging allows confirmation of the diagnosis, monitoring of the disorder, outcome assessment and complication identification. Weight-bearing radiography of the foot and ankle are gold standard for the diagnosis of AAFD. Magnetic Resonance Imaging (MRI) is not routinely needed for the diagnosis; however, it can be used to evaluate the spring ligament and the degree of PTT damage which can help to guide surgical plans and management in patients with severe deformity. Ultrasonography (US) can be considered another helpful tool to evaluate the condition of the PTT and other soft-tissue structures. Computed Tomography (CT) provides enhanced, detailed visualization of the hindfoot, and it is useful both in the evaluation of bone abnormalities and in the accurate evaluation of measurements useful for diagnosis and post-surgical follow-up. Other state-of-the-art imaging examinations, like multiplanar weight-bearing imaging, are emerging as techniques for diagnosis and preoperative planning but are not yet standardized and their scope of application is not yet well defined. The aim of this review, performed through Pubmed and Web of Science databases, was to analyze the literature relating to the role of imaging in the diagnosis and treatment of AAFD.
- Published
- 2023
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46. Intra-Articular Calcaneal Fractures: Comparison between Mini-Invasive Approach and Kirschner Wires vs. Extensive Approach and Dedicated Plate-A Retrospective Evaluation at Long-Term Follow-Up.
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Caravelli S, Gardini G, Pungetti C, Gentile P, Perisano C, Greco T, Rinaldi VG, Marcheggiani Muccioli GM, Tigani D, and Mosca M
- Abstract
Introduction: Calcaneal fractures (CF) are the most common tarsal fractures, representing up to 75% of foot fractures and 2% of all fractures. The aim of this retrospective study is to analyze fixation with Kirschner wires through a mini-invasive approach and dedicated plate and screws through an extended approach at long-term follow-up., Materials and Methods: Patients were radiographically and clinically evaluated at final follow-up, by using the validated American Orthopedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot score for the clinical-functional assessment, the Short-Form 12 (SF-12) for the physical and psychological domain assessment, and the Visual Analog Scale (VAS) for pain., Results: In total, 38 patients (42 CF) met the inclusion criteria and were retrospectively evaluated and divided into two groups (Kirschner group and plate group) consisting of 19 patients each. The overall mean follow-up was 59.4 ± 11.8 months. The average values of the post-operative clinical outcomes of the two groups KG and PG were, respectively, 70.7 ± 11.9 and 70.1 ± 10.9 (AOFAS), 45.7 ± 6.8 and 46.5 ± 10.8 (SF-12 PCS), 54.7 ± 9.9 and 50.9 ± 11.8 (SF-12 MCS) at the final follow-up., Conclusions: The present study showed that in the cases analyzed, the two surgical approaches used for the treatment of CF achieved comparable clinical outcomes. The only substantial difference found between the two groups of patients was the re-intervention rate that afflicted them.
- Published
- 2022
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47. Enhanced recovery (fast-track surgery) after total ankle replacement: The state of the art.
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Querci L, Caravelli S, Di Ponte M, Fuiano M, De Blasiis P, Sirico F, Baiardi A, Zannoni F, and Mosca M
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- Humans, Length of Stay, Recovery of Function, Postoperative Care, Postoperative Period, Arthroplasty, Replacement, Ankle
- Abstract
The post-operative results of a total ankle replacement are not determined solely by an optimal surgical technique, but by an appropriate anesthesiological and rehabilitative post-operative approach. Enhanced functional recovery often depends on a multidisciplinary approach based on a correct framework of the patient and his needs, requests, and characteristics. Extensive bibliographical research has been performed on Pubmed, Google Scholar, Scopus. This comprehensive and inclusive review of the literature aims to examine the state of the art of "fast-track" protocols employed in total ankle replacement (TAR), considering pre-operative preparation, anesthetic management, intraoperative and surgical factors, post-operative rehabilitative care and reduction of hospitalization time., Competing Interests: Declaration of Competing Interest The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (Copyright © 2022 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.)
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- 2022
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48. Custom-Made Implants in Ankle Bone Loss: A Retrospective Assessment of Reconstruction/Arthrodesis in Sequelae of Septic Non-Union of the Tibial Pilon.
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Caravelli S, Ambrosino G, Vocale E, Di Ponte M, Puccetti G, Perisano C, Greco T, Rinaldi VG, Marcheggiani Muccioli GM, Zaffagnini S, and Mosca M
- Subjects
- Humans, Tibia surgery, Ankle, Retrospective Studies, Arthrodesis methods, Disease Progression, Ankle Fractures complications, Ankle Fractures surgery, Tibial Fractures complications, Tibial Fractures surgery, Osteomyelitis complications, Osteomyelitis surgery
- Abstract
Background and Objectives : Treating segmental tibial and ankle bone loss after radical surgery for chronic osteomyelitis is one of the most challenging problems encountered by orthopaedic surgeons. Open tibia and ankle fractures occur with an incidence of 3.4 per 100,000 and 1.6 per 100,000, respectively, and there is a high propensity of developing fracture-related infection with associated chronic osteomyelitis in patients. Segmental tibial and ankle bone loss have recently received new and improved treatments. Materials and Methods : Above all, 3D printing allows for the customization of implants based on the anatomy of each patient, using a personalized process through the layer-by-layer deposition of materials. Results : This article presents different cases from the authors' experience. Specifically, four patients suffered tibia and ankle fractures and after radical surgery for chronic osteomyelitis combined with high-performance antibiotic therapy underwent ankle reconstruction/arthrodesis with custom-made tibial spacers. Conclusions : Thanks to 3D-printed patient-specific devices, it is possible to perform surgical procedures that, for anatomical reasons, would have been impossible otherwise. Moreover, an improvement in overall functionality and an important reduction in pain were shown in the last follow-up in all patients.
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- 2022
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49. Hallux rigidus: current concepts review and treatment algorithm with special focus on interposition arthroplasty.
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Di Caprio F, Mosca M, Ceccarelli F, Caravelli S, Vocale E, Zaffagnini S, and Ponziani L
- Subjects
- Humans, Treatment Outcome, Arthroplasty methods, Algorithms, Hallux Rigidus surgery, Metatarsophalangeal Joint surgery
- Abstract
Background and Aim of the Work: Hallux rigidus represents a surgical challenge, with a multitude of possible surgical options, but with no ideal procedures. The propose of this paper was to review the actual knowledge on the operative techniques, paying particular attention to the evolution of interposition arthroplasties, as an alternative to arthrodesis and prosthesis in the advanced stages of the disease., Methods: A comprehensive literature PubMed search was performed, and the actual literature regarding hallux rigidus was overviewed. The operative and nonoperative options for HR were described. Studies on interposition arthroplasty were classified by publication year, summarizing the operative technique, results and complications., Results: Among the various techniques for interposition arthroplasty, the Modified Oblique Keller Interposition Arthtoplasty (MOKCIA) showed the lower complication rate. It does not sacrifice the insertion of the flexor halluces brevis, maintaining the stability, length and strength of the big toe., Conclusions: Although long-term randomized controlled trials are lacking for interposition arthroplasties, the reported results are comparable to the other alternatives for the treatment of end-stage hallux rigidus, making this technique a valid alternative also in the young active patient, without precluding other end-stage procedures in case of failure. Based on the current knowledge, a treatment algorithm was developed, according to the Coughlin classification.
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- 2022
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50. Plate Augmentation in Aseptic Femoral Shaft Nonunion after Intramedullary Nailing: A Literature Review.
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Perisano C, Cianni L, Polichetti C, Cannella A, Mosca M, Caravelli S, Maccauro G, and Greco T
- Abstract
Background: Femoral shaft fractures (FSFs) are a frequent injury in traumatology for which intramedullary nailing (IMN) is considered the gold standard treatment. Nonunion (NU) is one of the most frequent complications in FSF treated with IMN, with a percentage from 1.1% to 14%. Plate augmentation (PA), the addition of a compression plate and screws, with or without bone graft has been described as an effective option for the treatment of NU, improving the biomechanical conditions at the fracture site. The aim of this review was to analyze the literature relating to the use of PA in NU after IMN in FSFs to assess the efficacy of the technique., Methods: An electronic search on PubMed, Google Scholar, and Web of Science was conducted to search for all studies concerning PA of femoral shaft NUs after IMN., Results: Twenty-four studies were included in the review comprising a total of 502 patients with a mean age of 39.5 years. Of these, 200 hundred patients had atrophic pseudoarthrosis and 123 had hypertrophic pseudoarthrosis, while in 179, the type of pseudoarthrosis was not reported. The most frequently used plate for PA was the dynamic compression plate (DCP); in 87.1% of the cases, the authors added a bone graft to the plate fixation. In 98.0% of the patients, a complete bone union was achieved in a mean time of 5.8 ± 2.12 months., Conclusion: The patients treated with PA included in this review showed a good rate of consolidation in the femoral shaft NUs, with good functional recovery and a low incidence of complications.
- Published
- 2022
- Full Text
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