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Segundo a Organização Mundial de Saúde (2010), a obesidade é um dos maiores problemas de saúde pública na atualidade. Em 2016, cerca de 650 milhões de adultos eram obesos e 380 milhões de crianças e adolescentes com idade até os 19 anos foram considerados com sobrepeso ou obesidade (WHO, 2018). A prevalência mundial triplicou entre o período de 1975 e 2016 nos adultos, e continua aumentando em países de baixa e média renda (NCD-RISC, 2017).

Introduction: Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system that consists of the development of autoantibodies against the myelin sheath in neuronal axons causing demyelinating inflammatory sites. It is a disease currently incurable. Objectives: The objective was to describe the epidemiological clinical profile of patients hospitalized with MS in the State of São Paulo, in the period from 2011 to 2021. Methods: This is an epidemiological, descriptive and retrospective study, with quantitative analysis, whose source of data was the Information System for Notifiable Diseases, from the Ministry of Health. The data were tabulated in graphs and tables using Microsoft Excel 2010. Results: 10,386 admissions of MS were reported in the state. Of the total cases, 67.4% occurred in females and 80.3% in race white. 43.5% of patients in the age group between 30 and 39 years. 94.4% were hospitalized on an elective basis. The average length of stay is between 3.3 days, with mortality rate representing 0.64% of the total. Conclusion: A higher prevalence was observed in the age range between 30 and 39 years and a predominance of hospitalizations among women. Although it is a disease with high morbidity and mortality, the mortality was low. It suggests that there are variables to be analyzed, such as a possible underreporting of this disease and also the advent of early diagnosis strategies and treatments that can modify the course of the disease, mitigating mortality.

Background: Dementia syndromes have a progressive and varied nature, causing cognitive and functional decay. Therefore, understanding the epidemiology of this disease is important for its screening. Objectives: To present the patients hospitalized in the state of São Paulo clinical-epidemiological profile, between March 2011 and February 2021. Design and settings: Descriptive, retrospective, and quantitative epidemiological study. Methodology: The data were collected in Sistema de Informação Hospitalares do Sistema Único de Saúde. The number of hospitalizations and mortality rate were analyzed, correlating them with sex, color, age group, care type, and year. Results: In 6572 hospitalizations, there was no sex majority. 20.3% of the patients did not present information about color. Among the identified, the majority was white (66.2%) or brown (24.7%). Individuals older than 60 years represented 62.6%, with peak between 70 and 79 years old. White population had the highest mortality rates (7.85 ‰), followed by the black population (7.55 ‰). The mortality rate was higher among women older than 80 years. Mortality in elective care (11.6 ‰) was approximately 4 times higher than in emergency care (2.77 ‰). Conclusions: The profile includes white and brown population, older than 60 years. Higher mortality rates in women older than 80 years may be related to their longer life expectancy. Higher mortality in elective care may indicate greater neurodegenerative diseases presence.