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1. Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi study

Author

Laheij, Alexa, Tonkaboni, Arghavan, Scott, Jacqui, Abasaeed, Rania, Kauzman, Adel, Flato, Adriana Do Socorro Lima, Gore, Adwaita, Hardman, Anne-Marie, Horvath, Agnes, Hovan, Allan, Al-Jamaei, Aisha, koizumi, Aya, Santos-Silva, Alan, Majorana, Alessandra, Giannini, Alexandre, Teixeira, Aléxia, Shazib, Muhammad Ali, Melvin, Alison, Filho, Aluísio Miranda, Gruza, Amanda, Brown-Dahl, Amber, Harilall, Amit, El Maghrabi, Amr, Rogulj, Ana Andabak, Curvo, Ana Raphaela, Soares, Ana Laura, Stringer, Andrea, Moreira, Andréa, Kurtzweil, Andy, Salaberry, Angelyn, Blazy, Anne, Gussgard, Anne Margrete, Lynge Pedersen, Anne Marie, Freidank, Annette, Ariyawardana, Anura, Ramseier, Adrian, Arends, Jann, Blanchard, Ariel, Paz, Adriana Sesti, Thermann, Angela, Poropat, Augusto, Freites-Martinez, Azael, Al-Azri, Abdul Rahman, Herlofson, Bente Brokstad, BalajiSubramanian, Sitaraman, Ballantyne, Barbara, Bektas-Kayhan, Kivanc, Hasséus, Bengt, Kaffenberger, Benjamin, Benites, Bernar, Kwong, Bernice, Test, Beth, Chiantia, Fernando, Pettersson, Bo, Framroze, Bomi, Bonomo, Pierluigi, Brzak, Božana Lončar, Dulmage, Brittany, Buga, Sorin, Spekssnijder, Caroline, Brown, Carlton, Melo, Antonio Carlos Moura de, Ribeiro, Ana Carolina, Silva, Caroline, Fulop, Caroline, Anderson, Carryn, Flaitz, Catherine, Massoud, Cathy, Migliorati, Cesar, Gross, Callie, Gandini, Chiara, Loprinzi, Charles, de Mooij, Charlotte, Hong, Catherine, Choi, Ying Chu, Choy, Maria, Boers-Doets, Christine, Schmeel, Leonard, Nagano, Cibele, Franco, Maria Coeli, Subramaniam, Courtney, Patrick, Carolyn, Poh, Catherine, Neuenschwander, Cristina, Virgen, Cesar, Riesenbeck, Dorothea, Weaver, Dale, Goldemberg, Daniel Cohen, Sundaresan, Daniel, Nunes, Daniela, Perez, Danyel, Travassos, Daphine, Yang, David, Ribeiro, Daniela, Kolbinson, Dean, Buick, Deborah, Saunders, Deborah, De Bortolli, Juliane, Chugh, Deepika, Markstrom, Denise, Travassos, Denise, Weikel, Dianna, Galiti, Dimitra, Peiris, Dinusha, Djordjevic, Fedja, Singhai, Pankaj, Keefe, Dorothy, Peterson, Douglas, Fonseca, Douglas, Pon, Doreen, Kovalenko, Iuliia, Polonskaia, Aleksandra, Caldas, Rogério, Saganski, Kevin, Néri, Julia, Abbott, Dennis, Yergolkar, Abhijna Vithal, Del Conte, Cristina, Passos, Januaria, Uezu, Katia, Silva, Paula, Gilbert, Steven, Yeoh, Keng, Jain, Kunal, Rastogi, Madhup, Sankaran, Satheeshkumar Poolakkad, Manne, Deborah, Shatokhina, Evgeniya, Adebayo-Olojo, Esther, Somogyi-Ganss, Eszter, Ehrenpreis, Eli, Bernaola-Paredes, Wilber, Fregnani, Eduardo, Cardoso, Elaci, Bardellini, Elena, Arvanitou, Eleni, Fontes, Elisa Kauark, Bruning, Elise, Neumann, Eloise, Madureira, Elsa, Ramires, Marcia, Papadopoulou, Erofili, Munhoz, Etiene, Spijkervet, Fred, Granzotto, Fabiana, Martins, Fabiana, Alves, Fabio, Mougeot, Farah, Aielli, Federica, Pigatti, Fernanda, Fonseca, Fernanda, Samim, Firoozeh, Carvalho, Flavia, Zelaya, Florence Cuadra, Freytes, Cesar, da Silveira, Gabriela, Torino, Gabriela, Martins, Gabriela, Silva, Geisa, Caro, Gemma, Bryan, Gemma, Radford, Georgette, Al-Qadami, Ghanyah, Albini, Giorgia, Mainville, Gisele, Gkardiakos, Georgios, Potter, Gleidston, Hoeberechts, Gulbin, Howarth, Gordon, Ottaviani, Giulia, Bradley, Grace, Verma, Gunjan, Santos, Gustavo dos, Randles-Guzzardi, Margaret, Engelbrecht, Hanlie, Wardill, Hannah, Hansen, Heidi, Hasan, Iquebal, Hata, Hironobu, Ullgren, Helena, Antunes, Heliton Spindola, Laís dos Santos, Heloísa, Weld, Howard, McInnes, Helen, Jungbluth, Hans Peter, Weng, Hsiaofen, Hewson, Ian, Santos, Ingrid, Illarramendi, Jorge, Semendric, Ines, Menge, Rol, Von Bultzingslowen, Inger, Melo, Maria da Gloria de, Leong, Iona, Fonseca, Isabella, Kalif, Isadora, Carroll, James, Coller, Janet, Beck-Mannagetta, Johann, Bowen, Joanne, Meurer, Jose, McCullough, Ricky, Powers, Jennifer, Gomez, Jesus, Lenjisa, Jimma, jaya Vangara, Leko, Jasna, Fall-Dickson, Jane, Mougeot, Jean-Luc, Fox, Joan, Epstein, Joel, Robijns, Jolien, Wu, Jonn, Palma, Patricio, Amaram-Davila, Jaya, Siderov, Jim, Raber-Durlacher, Judith, Dantas, Juliana, Jasper, Juliana, Monteiro, Juliana, Bruno, Julia, julie pfeffer, Ristivojevic, Julija Jovanovic, Brito, Juliana, Kuriakose, Jyothsna, Kabasawa, Yuji, Dave, Kanan, Barczyszyn, Karin, Lima, Karol Sartori, Secombe, Kate, White, Kate, Cooper, Kate, Katsura, Kouji, Biggs, Karen, Ciarrocca, Katharine, Dennis, Kristopher, Tomizuka, Ken, Hendler, Kevin, Komo, Ikuko, Skallsjö, Kristina, Hodgins, Kristy, Rupel, Katia, Tanaka, Keiko, Kurup, Seema, Gueiros, Luiz, Agatti, Larissa, Garzona-Navas, Laura, Guerra, Letícia, Portela, Leila, Iossi, Leilani, Elting, Linda, Baad-Hansen, Lene, Reeder, Leslie, Lang, Leticia, Menezes, Liciane, Braun, Liliana, Grando, Liliane, Lim, Mathew, Fernandez, Lina, McKeage, Lucy, Campos, Luana, Simonato, Luciana, Muniz, Luciana, van Draanen, Leah, Mizutani, Mieko, Huang, Tsai-Wei, Riad, Mahfujul, Nazar, Mahnoor, Souza, Maíra, Minamisako, Mariana, Pereira, Manoela, Mantelato, Carlos, Diniz-Freitas, Márcio, Montezuma, Marco, Andrade, Marco, Santos, Marcos, Gobbo, Margherita, Fortuna, Maria Caterina, Vitor, Mariana, Marinho, Joana, Markova, Alina, Knuchel, Marlyse, Carlesimo, Marta, Neves, Marta, Mazar, Andrew, Gomez Amarilla, Maria Cristina, Chambers, Mark, Araujo, Melissa de, Melo, Alexandre, Cole, Melody, Elsayed, Mohamed, Fliedner, Monica, Hauer-Jensen, Martin, Bouchacourt, Micaela, Brennan, Michael, Thirlwell, Michael, Nakamura, Michio, Nakagaki, Midori, Rossi, Camila, Miller, Robert, Kaprilian, Mireille, Kase, Michael, Dougan, Michael, Stokman, Monique, Monsen, Ragnhild, Morgan, Alisha, Harding, Jocelyn, Taleghani, Maryam, Genot, Marie-Therese, Seshadri, Mukund, Muzyka, Brian, Batista, Nancy, Gadd, Nancy, Tanda, Naoko, Nasr, Narmin, Garcia, Natália, Lee, Nathan, Palmier, Natalia, Brito-Dellan, Norman, Corbitt, Nancy, Pieralisi, Neli, Serrano, Verônica, Iacovelli, Nicola Alessandro, Blijlevens, Nicole, Sampaio, Norma Lúcia, Karra, Nour, Venkatesh, Niveditha, Yarom, Noam, Borin, Renata Cristina, Lemenchick, Olivia, Mendes, Ondina, Nicolatou-Galitis, Ourania, Shchitka, Vasiliy, Bossi, Paolo, Reis, Paula, Santos, Paulo Sérgio, Fernandez-Ortega, Paz, Parker, Ira, García, Raquel, Fritz, Peter, Peters, Edmund, Gardner, Pamela, Girons, Pierre Saint, Tiwari, Priya, Chaturvedi, Pravin, de Moraes, Tais, Andrade, Priscila, Nair, Raj, Gibson, Rachel, Gururaj, Rachita, Abdalla-Aslan, Ragda, Thota, Raghu, Lalla, Rajesh, Mendes, Rui Amaral, Prado, Raquel Almeida, Ongole, Ravikiran, Taybos, George, Mackey, Regina, Rego, Renata, Camilotti, Renata, Ferrari, Renata, Junior, Renato, Bensadoun, Rene-Jean, Logan, Richard, Sales, Roberta, Zanicotti, Roberta, Tunes, Roberta, Mauceri, Rodolfo, Feitoza, Rosiene, Ruddy, Kathryn, Rybczyk, Cynthia, Trager, Stephanie, Mitsunaga, Sachiyo, Gunathilake, Sahani, Saini, Rajan, Salvestrini, Viola, Mukhopadhyay, Sandip, Angeloz, Sandrina, Sankar S, Pramod, Barbosa, Luciana S Barbosa, Volkova, Elena, Elad, Sharon, Cantoreggi, Sergio, Gordon, Sharon, Brown, Shelly, Janine Tam, Shu Yie, Faleiro, Sibelle, da Silva, Silmara, de Oliveira, Silvia, Jensen, Siri Beier, Skrinjar, Ivana, Beaumont, Sophie, Sperandio, Felipe, Reese, Sandra, Roser, Steven, Seo, Sachiko, van Leeuwen, Stephanie, Sonis, Stephen, Bernard, Stephen, Samuel, Stephen Rajan, Taylor, Stuart, Maitra, Suranjan, Skulski, Susanne, Carlisle, Suzanne, Avon, Sylvie Louise, Yokota, Tomoya, Yurikusa, Takashi, Polvora, Tabata Santos, Kelock, Tabitha, Fernandes, Tauana, Wain, Taylor, Brown, Timothy, Tetsuhito konishi, Ferreira, Thalyta Amanda, Kataoka, Tomoko, Kelly, Thomas, Mori, Takehiko, Higuchi, Tomoko, Saeki, Toshiaki, Tsoukalas, Nikolaos, De Vandeul, Typhaine Maupoint, Usubuchi, Masatoshi, Lacerda, Vanessa, Tilly, Vanessa, Vigarios, Emmanuelle, Villa, Alessandro, Torregrossa, Vinicius, Selvaraj, Vinodh Kumar, Sarmento, Viviane, Heng, Vivien, Gomes-Silva, Wagner, Kandwal, Abhishek, Wilberg, Petter, Miranda e Silva, Wanessa, I'zzah Wan Mohamad Zain, Wan Nor, Park, Wonse, Tissing, Wim, Soga, Yoshihiko, Van Sebille, Bella, Matsuda, Yuhei, Zadik, Yehuda, Cao, Katrina, Cheung, Yin Ting, Fregnani, Eduardo Rodrigues, Van Sebille, Ysabella, Kauark-Fontes, Elisa, McCurdy-Franks, Emma, Finkelstein, Joel, McCarvell, Victoria, Amaral Mendes, Rui, Speksnijder, Caroline Margina, and Wardill, Hannah Rose

Published
2024
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2. Italian National Registry of Alopecia Areata: an epidemiological study of 699 Italian patients

Author

PIRACCINI, Bianca Maria, primary, RAPPARINI, Luca, additional, QUADRELLI, Federico, additional, ALESSANDRINI, Aurora, additional, BRUNI, Francesca, additional, CEDIRIAN, Stephano, additional, PAMPALONI, Francesca, additional, MARCELLI, Emanuela, additional, BORTOLANI, Barbara, additional, GIAMPIERI, Enrico, additional, GALLO, Giuseppe, additional, TORRELLI, Francesca, additional, SCIAMARRELLI, Nadia, additional, QUAGLINO, Pietro, additional, TOMASINI, Carlo, additional, BARRUSCOTTI, Stefania, additional, AMBROGIO, Francesca, additional, FOTI, Caterina, additional, PICCIALLO, Michele, additional, CARO, Gemma, additional, ROSSI, Alfredo, additional, PELLACANI, Giovanni, additional, ALA, Lorenzo, additional, ACRI, Maria Cristina, additional, DILUVIO, Laura, additional, MATTEINI, Enrico, additional, BIANCHI, Luca, additional, ARGENZIANO, Giuseppe, additional, BABINO, Graziella, additional, FULGIONE, Elisabetta, additional, GNESOTTO, Laura, additional, SECHI, Andrea, additional, NALDI, Luigi, additional, TASSONE, Francesco, additional, PERIS, Ketty, additional, CALDAROLA, Giacomo, additional, CAPOSIENA CARO, Raffaele Dante, additional, BAZZACCO, Giulia, additional, ZALAUDEK, Iris, additional, VASTARELLA, Maria, additional, CANTELLI, Mariateresa, additional, PATRÌ, Angela, additional, DALL’OGLIO, Federica, additional, LACARRUBBA, Francesco, additional, MICALI, Giuseppe, additional, FRAGHÌ, Alessandro, additional, BOCCALETTI, Valeria, additional, MARZANO, Angelo Valerio, additional, BARBARESCHI, Mauro, additional, SILVIO, Martina, additional, VAGNOZZI, Emanuele, additional, FARGNOLI, Maria Concetta, additional, CAPONIO, Chiara, additional, ATZORI, Laura, additional, SANNA, Silvia, additional, ANEDDA, Jasmine, additional, FELICIANI, Claudio, additional, DE FELICI DEL GIUDICE, Maria Beatrice, additional, SCANDAGLI, Ilaria, additional, PRIGNANO, Francesca, additional, RONGIOLETTI, Franco, additional, PODO BRUNETTI, Antonio, additional, BIGOTTO, Gianmarco D., additional, OFFIDANI, Anna Maria, additional, SIMONETTI, Oriana, additional, LEMBO, Serena, additional, RAIMONDO, Annunziata, additional, BALESTRI, Riccardo, additional, IORIS, Tommaso, additional, GISONDI, Paolo, additional, BELLINATO, Francesco, additional, TROVATO, Emanuele, additional, CINOTTI, Elisa, additional, PAPINI, Manuela, additional, CICOLETTI, Michela, additional, CORAZZA, Monica, additional, and STARACE, Michela, additional

Published
2024
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3. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: A prospective, randomized, controlled, assessor blinded, 3‐arm, pilot trial.

Author

Rossi, Alfredo and Caro, Gemma

Subjects
*MINOXIDIL, *FINASTERIDE, *BALDNESS, *APPRAISERS, *FOLLICLE-stimulating hormone
Abstract

Purpose: Topical minoxidil (MNX) 2%–5% and oral finasteride (F) 1 mg/day are the only two pharmacological treatments authorized for androgenetic alopecia (AGA). Recently, a 2.2 mg/mL topical formulation of F was developed to minimize the systemic adverse effects associated with the oral formula. MNX and F act through different mechanisms; therefore, their association could improve clinical efficacy. To evaluate the efficacy of the association of 5% MNX and 0.25% topical F compared to their use in monotherapy, a 6‐month, prospective, randomized, assessor‐blinded trial was conducted. Patients and Methods: Forty‐two males, mean age 24 ± 3 years, with AGA (I–VII of Norwood‐Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was evaluated at baseline and after 3 and 6 months using a global photography score (GPAS; from −3 to +3) and trichoscopy evaluation and assessed by an investigator unaware of treatment allocation. At baseline and after treatments, the serum levels of follicle‐stimulating hormone (FSH), luteinizing hormone (LH), dehydroepiandrosterone sulfate (DHEA‐S), and testosterone were also evaluated. Results: All treatments resulted in an increase in hair density compared to baseline. However, this improvement was significant only for group A (MNX + F), both at three (+56 density/cm2, p < 0.05) and six (+81 density/cm2, p < 0.001) months. The mean change from baseline in hair density was higher for group A compared to other groups and statistically different compared to group B (F) (p < 0.01), both after 3 and 6 months. Group A showed a global photographic assessment score (GPAS) significantly higher compared to group B (p < 0.001) and group C (p < 0.05) both at 3 and 6 months (2.0 ± 0.7 vs. 0.6 ± 0.8 and 1.3 ± 0.6; respectively). A significantly greater percentage of subjects in Group A achieved a GPAS score of ≥2 in comparison with Groups B and C both after 3 and 6 months (79% vs. 8% and 41%, respectively). No significant differences were observed in mean hair diameter and hormonal levels between the three groups. Good tolerability was observed in all treated groups. Conclusion: The association of 5% MNX lotion and 0.25% F in spray formulation in patients with AGA showed a significantly higher clinical and instrumental efficacy compared to the monotherapies, with comparable tolerability and safety profile. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Detection of novel therapies using a multi‐national , multi‐institutional registry of cutaneous immune‐related adverse events and management

Author

Mital, Rohan, primary, Otto, Tracey S., additional, Savu, Andrei, additional, Baumrin, Emily, additional, Cardones, Adela R., additional, Carlesimo, Marta, additional, Caro, Gemma, additional, Freites‐Martinez, Azael, additional, Hirner, Jesse P., additional, Markova, Alina, additional, McLellan, Beth N., additional, Rossi, Alfredo, additional, Sauder, Maxwell B., additional, Seminario‐Vidal, Lucia, additional, Sibaud, Vincent, additional, Owen, Dwight H., additional, Dulmage, Brittany O., additional, Chen, Steven T., additional, and Kaffenberger, Benjamin H., additional

Published
2023
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14. Frontal Fibrosing Alopecia: A New Association with Lichen Sclerosus in Men

Author

Rossi, Alfredo, Tadiotto Cicogna, Giulia, Caro, Gemma, Fortuna, Maria Caterina, Magri, Francesca, and Grassi, Sara

Subjects
Case Series
Abstract

BACKGROUND: Frontal fibrosing alopecia (FFA) is a scarring alopecia that has been reported mostly in postmenopausal women and is characterized by frontotemporal hairline. Currently, there are only a few reports about FFA in male patients. OBJECTIVE: This study sought to analyze clinical and trichoscopic features of FFA in a case series of men and to describe the main features of FFA in male patients through a review of the literature. METHODS: Male patients with clinical and trichoscopical signs of FFA, histologically confirmed, who attended to our clinic from 2014 to 2019 were included in our study. From each patient, clinical and trichoscopic data were collected. RESULTS: Eight men with an average age of 59 years were recruited. In five patients, serrated hairline recession (i.e., a “zig-zag” pattern) was present, while three presented with linear hairline recession. Also, the eyebrows (n=3 patients), sideburns (n=2 patients), and beard (n=2 patients) were involved. Surprisingly, in two patients, an association with lichen sclerosus (LS) was present. CONCLUSION: To the best of our knowledge, this is the first report of a serrated hairline recession pattern in male patients with FFA. A new association between FFA and LS in men was also found. Further studies need to establish the extent of this association and facilitate a better comprehension of the pathophysiologic mechanisms underlying these two diseases.

Published
2021

17. Capillaroscopy: a new application for the evaluation of vascular side-effects induced by chemotherapy

Author

Cardone, Michele, Caro, Gemma, Beatrice, Amorosi, Antonio, Cristaudo, Morrone, Aldo, Calvieri, Stefano, Carlesimo, Marta, Fortuna, MARIA CATERINA, and Rossi, Alfredo

Subjects
Infectious Diseases, Nails, capillaroscopy, chemotherapy, oncology, Humans, Dermatology, Middle Aged, Prognosis, Capillaries, Dilatation, Pathologic, Microscopic Angioscopy
Abstract

Cancer survivors are rising up, but this better survival is accompanied by possible treatments side-effects. In particular, cardiovascular effects are commonly reported, even if vascular damage is not necessarily connected to clinical manifestations. Periungual microcircle evaluation through capillaroscopy could identify asymptomatic patients with high risk of cerebro-cardio-vascular disease. The aim of this pivotal study was to evaluate videocapillaroscopy in patients who undergo chemotherapy, in order to understand if it could represent in future a prognostic tool to predict the risk of cardio-cerebro-vascular events.We conducted an open-label, uncontrolled study. Patients affected by solid tumors were enrolled. Each subject underwent a clinical evaluation and a videocapillaroscopic examination.We selected 25 patients. Mean age was 55.48 years. Time interval between the start of chemotherapy and capillaroscopy: average 41 months. From our analysis it emerges that ectasia and hemorrhages could be a possible marker of capillary insult caused by chemotherapy.Our study showed the presence of capillaroscopic features that may be peculiar in chemotherapy-induced endothelial damage. The individuation of capillaroscopic alteration specific for chemotherapy-induced endothelial injury could be an important tool to identify patients with high cardiovascular risk.

Published
2021
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21. Isochemotopic response: the first case on a scar

Author

CARLESIMO, Marta, primary, CORTESI, Enrico, additional, D’ARINO, Andrea, additional, PIGLIACELLI, Flavia, additional, CARO, Gemma, additional, ZANCLA, Serena, additional, FORTUNA, Caterina M., additional, GRIFALCHI, Federico, additional, and ROSSI, Alfredo, additional

Published
2021
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31. Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients

Author

Rossi, Alfredo, primary, Magri, Francesca, additional, D'Arino, Andrea, additional, Pigliacelli, Flavia, additional, Muscianese, Marta, additional, Leoncini, Pierpaolo, additional, Caro, Gemma, additional, Federico, Alessandro, additional, Fortuna, Maria Caterina, additional, and Carlesimo, Marta, additional

Published
2020
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33. Recommendations on trichological treatments during COVID-19 pandemic.

Author

Rossi, Alfredo, Magri, Francesca, Caro, Gemma, Federico, Alessandro, Di Fraia, Marco, Muscianese, Marta, Fortuna, Maria Caterina, and Carlesimo, Marta

Subjects
COVID-19 pandemic, COVID-19 treatment, COVID-19, SARS-CoV-2, COMMUNICABLE diseases
Abstract

COVID-19 is an infectious disease caused by the novel coronavirus SARS-CoV-2, which rapidly spreads via respiratory droplets and is the cause of the current pandemic. In this alarming situation, it is a delicate matter how to visit patients safely and how to manage their chronic treatments. The aim of this paper is to examine in detail the potential impact on SARS-CoV-2 infection of treatments routinely used in trichology and to provide a useful guide for the therapeutic management of trichological patients in this new COVID-19 era. [ABSTRACT FROM AUTHOR]

Published
2022
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36. Italian Guidelines in diagnosis and treatment of alopecia areata

Author

Rossi, Alfredo, primary, Muscianese, Marta, additional, Piraccini, Bianca M., additional, Starace, Michela, additional, Carlesimo, Marta, additional, Mandel, Victor D., additional, Alessandrini, Aurora, additional, Calvieri, Stefano, additional, Caro, Gemma, additional, D'arino, Andrea, additional, Federico, Alessandro, additional, Magri, Francesca, additional, Pigliacelli, Flavia, additional, Amendolagine, Graziana, additional, Annunziata, Maria C., additional, Arisi, Maria C., additional, Astorino, Stefano, additional, Babino, Graziella, additional, Bardazzi, Federico, additional, Barruscotti, Stefania, additional, Belloni Fortina, Anna, additional, Borghi, Alessandro, additional, Bruni, Francesca, additional, Caccavale, Stefano, additional, Calzavara-Pinton, Piergiacomo, additional, Cameli, Norma, additional, Cardone, Michele, additional, Carugno, Andrea, additional, Coppola, Rosa, additional, Dattola, Annunziata, additional, De Felici Del Giudice, Maria B., additional, Di Cesare, Antonella, additional, Dika, Emi, additional, Di Nunno, Donato, additional, D'ovidio, Roberto, additional, Fabbrocini, Gabriella, additional, Feliciani, Claudio, additional, Fulgione, Elisabetta, additional, Galluzzo, Marco, additional, Garcovich, Simone, additional, Garelli, Valentina, additional, Guerriero, Cristina, additional, Hansel, Katharina, additional, La Placa, Michelangelo, additional, Lacarrubba, Francesco, additional, Lora, Viviana, additional, Marinello, Elena, additional, Megna, Matteo, additional, Micali, Giuseppe, additional, Misciali, Cosimo, additional, Monari, Paola, additional, Monfrecola, Giuseppe, additional, Neri, Iria, additional, Offidani, Annamaria, additional, Orlando, Gloria, additional, Papini, Manuela, additional, Patrizi, Annalisa, additional, Piaserico, Stefano, additional, Rivetti, Niccolò, additional, Simonetti, Oriana, additional, Stan, Teodora R., additional, Stingeni, Luca, additional, Talamonti, Marina, additional, Tassone, Francesco, additional, Villa, Lucia, additional, Vincenzi, Colombina, additional, and Fortuna, Maria C., additional

Published
2019
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42. Acne keloidalis nuchae in a Caucasian young man

Author

Tammaro, Antonella, primary, Caro, Gemma, additional, Parisella, Francesca R., additional, Magri, Francesca, additional, Giordano, Domenico, additional, Pigliacelli, Flavia, additional, and Persechino, Severino, additional

Published
2019
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45. A new treatment of alopecia induced by palbociclib: Topical cetirizine.

Author

Caro, Gemma, Fortuna, Maria C, Magri, Francesca, Federico, Alessandro, Carlesimo, Marta, and Rossi, Alfredo

Subjects
*BALDNESS, *CETIRIZINE, *TREATMENT effectiveness, *TRANSFERASES, *CUTANEOUS therapeutics, *BREAST tumors, *DISEASE management
Abstract

Introduction: Recently CDK4/6 inhibitors have been introduced for the treatment of hormone positive breast cancer resistant to endocrine therapy. Among their side effects, alopecia is often reported being associated to patients' distress and depressive symptoms. Case Report: We report the case of a 70-year-old woman affected by breast cancer in treatment with Palbociclib, who developed alopecia. Management and Outcome: We prescribed a topical solution with cetirizine. Global photography, trichoscopy and trichogram were assessed. All evaluations demonstrated alopecia improvement. Discussion: Currently, no treatment options for CDK 4/6 inhibitors induced alopecia have been proposed. Herein, we report the use of topical cetirizine. [ABSTRACT FROM AUTHOR]

Published
2021
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46. Frontal fibrosing alopecia and genital Lichen sclerosus: Single‐center experience.

Author

Grassi, Sara, Tadiotto Cicogna, Giulia, Magri, Francesca, Caterina Fortuna, Maria, Caro, Gemma, Pernazza, Angelina, Soda, Giuseppe, Miraglia, Emanuele, Giustini, Sandra, Carlesimo, Marta, and Rossi, Alfredo

Subjects
LICHEN sclerosus et atrophicus, BALDNESS, LICHEN planus, AUTOIMMUNITY, GENDER, ORAL lichen planus, FRONTOTEMPORAL lobar degeneration
Abstract

Background: Despite the incidence of Frontal fibrosing alopecia (FFA) has been increasing in last two decades, the pathophysiology and trigger factors of FFA have not been yet fully understood. Aims: The aim of this study was to describe epidemiology, clinical and trichoscopic features and comorbidities of FFA patients, in order to improve the understanding of this disease. Patients/Methods: A retrospective, observational monocentric study was conducted from 2003 to 2019. Data concerning epidemiology (age, gender, age of menopause, and age of FFA onset), comorbidities, current therapies, localization of FFA (such as frontotemporal hairline, occipital, eyebrow, eyelash, beard, sideburns, and body hair), presence of papules and sign of Lichen planus (LP) at skin, mucosae and/or nail were collected for each patient included. Results: A total of 119 Caucasian, adult patients (8 men and 111 female) with FFA were enrolled in the study. Cutaneous, mucosal, or nail localization of LP were found in 16% of our subjects. Interestingly, 15 out of 119 subjects (10.61%) were affected by concomitant genital Lichen sclerosus (LS) and 5 out of these 15 patients (4.38%) presented both LS and LP in association with FFA. Conclusion: Considering the high prevalence of LS in FFA patients in our case series, and the frequency of autoimmune comorbidities in both LS and FFA, it is possible to hypothesize an autoimmune process in both conditions. Further studies are needed for a better understanding of the nature of the association between LS and FFA. [ABSTRACT FROM AUTHOR]

Published
2021
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47. Dermatologic management of oncotherapy side effects: A proposed algorithm.

Author

Carlesimo, Marta, Pigliacelli, Flavia, D'Arino, Andrea, Caro, Gemma, Fortuna, Maria Caterina, and Rossi, Alfredo

Subjects
TARGETED drug delivery, HORMONE therapy, DRUG dosage, SKIN care, CANCER treatment
Abstract

Since the introduction of the first chemotherapeutic regimens for the treatment of oncological disease, hundreds of drugs have been approved for cancer treatment and many more are under investigation. The development of newer drugs such as target therapies, immuno‐oncotherapies, and hormonal therapies has increased in specificity with the development of smaller molecules and more selective targets. Cutaneous side effects are now well known for both standard chemotherapy and targeted therapies. The correct diagnosis and management of these effects are of vital importance both to optimize therapeutic success rates and to reduce the patient's suffering. In fact, the appearance of a cutaneous adverse event can be responsible for a reduction in drug dosage or worse its suspension. In order to achieve this objective, we propose a management algorithm, based on three different steps, before, during, and after the oncological treatments, respectively. Our proposal underlines the importance of correct skin care measures to limit or reduce the severity of side effects. [ABSTRACT FROM AUTHOR]

Published
2021
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48. Associations between alopecia areata and multiple sclerosis: a report of two cases and review of the literature.

Author

Rossi, Alfredo, Muscianese, Marta, Federico, Alessandro, Magri, Francesca, Caro, Gemma, Fortuna, Maria Caterina, D'Arino, Andrea, Pigliacelli, Flavia, and Carlesimo, Marta

Subjects
ALOPECIA areata, MULTIPLE sclerosis, LITERATURE reviews, AUTOIMMUNE thyroiditis, PATHOLOGY, T helper cells
Abstract

Alopecia areata (AA) is an immune-mediated inflammatory disorder that targets anagen phase hair follicles (HFs), leading to nonscarring hair loss.[1] Several autoimmune diseases are commonly associated with AA. Herein we describe two cases (Table) of patients affected by AA, who have developed after several years multiple sclerosis (MS), which is one of the most frequent autoimmune diseases of the central nervous system. Tada I et al. i [3] conducted a study on 70 patients with MS and found that five patients (Male/Female = 4/1) were complicated with AA. Interestingly, AA has been recently hypothesized as a possible side effect of anti-CD52 monoclonal antibody alemtuzumab, which is used for treatment of relapsing-remitting MS.[[5], [7]] In fact, AA had been reported during alemtuzumab therapy in five patients. [Extracted from the article]

Published
2020
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49. Dermoscopy and confocal microscopy for different chemotherapy‐induced alopecia (CIA) phases characterization: Preliminary study.

Author

Franceschini, Chiara, Garelli, Valentina, Persechino, Flavia, Sperduti, Isabella, Caro, Gemma, Rossi, Alfredo, and Ardigò, Marco

Subjects
CONFOCAL microscopy, BALDNESS, DISEASE progression, REFLECTANCE
Abstract

Background: Chemotherapy‐induced alopecia (CIA) affects 65% of patients receiving chemotherapy regimens and is often identified with the massive hair loss stage. Reflectance confocal microscopy (RCM) is a noninvasive technique used in alopecia assessment for disease characterization and state of activity. Objective: To describe RCM features of CIA in different timing and identify specific phases of alopecia development. Methods: A total of 16 patients treated with chemotherapy underwent dermoscopy and RCM evaluations four times during the observation: 2 and 4‐6 weeks after starting and 3 and 6 months after the end of chemotherapy. Ten examinations for each stage were performed. Results: Four phases of CIA have been identified. Initial hair loss showed specific dots not previously described, named CIA dots. massive hair loss phase was characterized by black dots (10/10 pt), CIA dots (8/10 pt) and hair shaft abnormalities. Three months after the end of chemotherapy, during the partial regrowth phase, 10/10 patients showed thin hair in regrowth and 8/10 presented black and yellow dots. At 6 months, normal hair in regrowth appears in all patients (total regrowth phase). Conclusions: Chemotherapy‐induced alopecia has to be considered as a dynamic process with specific phases characterized by distinctive dermoscopic and confocal features. [ABSTRACT FROM AUTHOR]

Published
2020
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