128 results on '"Caron, Nicholas S."'
Search Results
2. Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein A-I nanodisks for Huntington disease
3. High-resolution laser spectroscopy of the [formula omitted][formula omitted] transition in YbOD
4. Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein A-I nanodisks
5. Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound
6. Plasma and CSF neurofilament light chain are stabilized in response to mutant huntingtin lowering in the brain of Huntington disease mice
7. Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline
8. Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies
9. Reduced S-acylation of SQSTM1/p62 in Huntington disease is associated with impaired autophagy
10. High-resolution laser spectroscopy of the Ã2Π1/2−X̃2Σ+ 000 transition in YbOD
11. Limitations of Dual-Single Guide RNA CRISPR Strategies for the Treatment of Central Nervous System Genetic Disorders
12. Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease
13. Additional file 3 of Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
14. Additional file 6 of Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
15. Additional file 2 of Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
16. Additional file 8 of Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
17. Additional file 1 of Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
18. Additional file 7 of Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
19. Additional file 5 of Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
20. Additional file 4 of Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
21. Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity
22. D16 Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity
23. I03 CAG-targeted brain-permeable protein lowering strategy tested in polyQ mouse models
24. D02 Precise and allele-specific quantitation of endogenous HTT transcript alleles using droplet-digital PCR
25. Constitutive ablation of caspase-6 reduces the inflammatory response and behavioural changes caused by peripheral pro-inflammatory stimuli
26. Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
27. Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice
28. Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity
29. Reliable Resolution of Full-Length Huntingtin Alleles by Quantitative Immunoblotting
30. Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions
31. Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease
32. DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease
33. The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons
34. Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease
35. A Comprehensive Haplotype-Targeting Strategy for Allele-Specific HTT Suppression in Huntington Disease
36. Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease
37. The interaction of aging and oxidative stress contributes to pathogenesis in mouse and human Huntington disease neurons
38. Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease
39. Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease
40. Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease
41. Therapeutic approaches to Huntington disease: from the bench to the clinic
42. Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease.
43. Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease.
44. Feeding schedule and proteolysis regulate autophagic clearance of mutant huntingtin
45. L8 Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of huntington’s disease
46. Laquinimod decreases Bax expression and reduces caspase-6 activation in neurons
47. Using Förster Resonance Energy Transfer (FRET) To Define the Conformational Changes of Huntingtin at the Clinical Threshold for Huntington’s Disease
48. Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
49. Huntingtin Haplotypes Provide Prioritized Target Panels for Allele-specific Silencing in Huntington Disease Patients of European Ancestry
50. Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.