37 results on '"Carrière K"'
Search Results
2. A Method of Comparison for Standardized Rates of Low-Incidence Events
- Author
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Carriere, K. C. and Roos, Leslie L.
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- 1997
3. Population Health and Health Care Use: An Information System for Policy Makers
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Roos, Noralou P., Black, Charlyn, Frohlich, Norman, DeCoster, Carolyn, Cohen, Marsha, Tataryn, Douglas J., Mustard, Cameron A., Roos, Leslie L., Toll, Fred, Carrière, K. C., Burchill, Charles A., MacWilliam, Leonard, and Bogdanovic, Bogdan
- Published
- 1996
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4. Mindfulness‐based interventions for weight loss: a systematic review and meta‐analysis
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Carrière, K., Khoury, B., Günak, M. M., and Knäuper, B.
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- 2018
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5. General Mixed-Data Model: Extension of General Location and Grouped Continuous Models
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de Leon, Alexander R. and Carrière, K. C.
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- 2007
6. Assessing Socioeconomic Effects on Different Sized Populations: To Weight or Not to Weight?
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Frohlich, N., Carriere, K. C., Potvin, L., and Black, C.
- Published
- 2001
7. Author response to ‘Effects of mindfulness on weight loss’ by Dr. Kristina Bergman
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Carrière, K., primary, Khoury, B., additional, and Knäuper, B., additional
- Published
- 2018
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- View/download PDF
8. Examining the number and quality of physical activity-related if-then plans for weight loss success: Farah Islam
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Islam, F, primary, Xu, Z, additional, Ames-Bull, A, additional, Carrière, K, additional, Voloshyn, A, additional, Sasson, M, additional, Chamandy, M, additional, Ivanova, E, additional, and Knäuper, B, additional
- Published
- 2018
- Full Text
- View/download PDF
9. Mindfulness-based interventions for weight loss: a systematic review and meta-analysis
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Carrière, K., primary, Khoury, B., additional, Günak, M. M., additional, and Knäuper, B., additional
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- 2017
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10. Examining the number and quality of physical activity-related if-then plans for weight loss success
- Author
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Islam, F, primary, Xu, Z, additional, Ames-Bull, A, additional, Carrière, K, additional, Voloshyn, A, additional, Sasson, M, additional, Chamandy, M, additional, Ivanova, E, additional, and Knäuper, B, additional
- Published
- 2017
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- View/download PDF
11. Lessons Learned from an ACT-Based Physician-Delivered Weight Loss Intervention: A Pilot RCT Demonstrates Limits to Feasibility
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Frayn Mallory, Carrière Kimberly, and Knäuper Bärbel
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primary care ,obesity ,weight loss ,weight loss interventions ,emotional eating ,Psychology ,BF1-990 - Abstract
Background: Acceptance and Commitment Therapy (ACT) interventions have shown to be effective in facilitating weight loss for emotional eaters, however, the lack of accessibility of these interventions limits their impact. The present study aimed to increase the accessibility of an ACT intervention for emotional eaters through delivery by physicians.
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- 2020
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12. A measure of continuity of care based on the multiplicative intensity model.
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Hussein, A., Carrière, K. C., and Carrière, K C
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- 2002
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13. An improved CML estimation procedure for the Rasch model with item response data.
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Sheng, Xiaoming, Carrière, K. C., and Carrière, K C
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- 2002
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14. Strategies for Analyzing Missing Item Response Data with an Application to Lung Cancer
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Sheng, Xiaoming, primary and Carrière, K. C., additional
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- 2005
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15. HOW GOOD IS A NORMAL APPROXIMATION FOR RATES AND PROPORTIONS OF LOW INCIDENCE EVENTS?
- Author
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Carrière, K. C., primary
- Published
- 2001
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- View/download PDF
16. ROBUSTNESS OF PROCEDURES FOR THE BEHRENS-FISHER PROBLEMS: EXTENSION TO BIVARIATE NORMAL MIXTURES
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Hussien, A., primary and Carrière, K., additional
- Published
- 2001
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17. The role of proxy information in missing data analysis.
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Rong Huang, Yuanyuan Liang, and Carrière, K. C.
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MISSING data (Statistics) ,DATA analysis ,CLINICAL trials ,ESTIMATION theory ,MULTIVARIATE analysis - Abstract
This article investigates the role of proxy data in dealing with the common problem of missing data in clinical trials using repeated measures designs. In an effort to avoid the missing data situation, some proxy information can be gathered. The question is how to treat proxy information, that is, is it always better to utilize proxy information when there are missing data? A model for repeated measures data with missing values is considered and a strategy for utilizing proxy information is developed. Then, simulations are used to compare the power of a test using proxy to simply utilizing all available data. It is concluded that using proxy information can be a useful alternative when such information is available. The implications for various clinical designs are also considered and a data collection strategy for efficiently estimating parameters is suggested. [ABSTRACT FROM AUTHOR]
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- 2005
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18. Effects of long-term bronchodilators in bronchiectasis patients with airflow limitation based on bronchodilator response at baseline
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Jeong HJ, Lee H, Carriere KC, Kim JH, Han JH, Shin B, Jeong BH, Koh WJ, Kwon OJ, and Park HY
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Bronchodilator effect ,bronchodilator agents ,bronchiectasis ,airway obstruction ,Diseases of the respiratory system ,RC705-779 - Abstract
Ho Jung Jeong,1,* Hyun Lee,1,* Keumhee C Carriere,2,3 Jung Hoon Kim,1 Jin-Hyung Han,1 Beomsu Shin,1 Byeong-Ho Jeong,1 Won-Jung Koh,1 O Jung Kwon,1 Hye Yun Park1 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University of Medicine, Seoul, South Korea; 2Department of Mathematical and Statistical Sciences, University of Alberta, Edmonton, AB, Canada; 3Biostatistics and Clinical Epidemiology Center, Samsung Medical Center, Seoul, South Korea *These authors contributed equally to this work Purpose: The association between positive bronchodilator response (BDR) at baseline and the effect of long-term bronchodilator therapy has not been well elucidated in patients with bronchiectasis. The aims of our study were to explore the association between positive BDR at baseline and lung-function improvement following long-term (3–12 months) bronchodilator therapy in bronchiectasis patients with airflow limitation. Materials and methods: The medical records of 166 patients with clinically stable bronchiectasis who underwent baseline pre- and postbronchodilator spirometry and repeated spirometry after 3–12 months of bronchodilator therapy were retrospectively reviewed. For analysis, patients were divided into two groups, responders and poor responders, based on achievement of at least 12% and 200 mL in forced expiratory volume in 1 second (FEV1) following bronchodilator therapy from baseline FEV1. Results: A total of 57 patients (34.3%) were responders. These patients were more likely to have positive BDR at baseline than poor responders (38.6% [22 of 57] vs 18.3% [20 of 109], P=0.004). This association persisted after adjustment for other confounding factors (adjusted odds ratio 2.298, P=0.034). However, we found FEV1 improved significantly following long-term bronchodilator therapy, even in patients without positive BDR at baseline (change in FEV1 130 mL, interquartile range -10 to 250 mL; P
- Published
- 2016
19. Comorbidity as a contributor to frequent severe acute exacerbation in COPD patients
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Jeong SH, Lee H, Carriere KC, Shin SH, Moon SM, Jeong BH, Koh WJ, and Park HY
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Asthma ,chronic obstructive pulmonary disease ,comorbidity ,exacerbation. ,Diseases of the respiratory system ,RC705-779 - Abstract
Suk Hyeon Jeong,1,* Hyun Lee,1,* KC Carriere,2,3 Sun Hye Shin,1 Seong Mi Moon,1 Byeong-Ho Jeong,1 Won-Jung Koh,1 Hye Yun Park1 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; 2Department of Mathematical and Statistical Sciences, University of Alberta, Edmonton, Alberta, Canada; 3Biostatistics and Clinical Epidemiology Center, Samsung Medical Center, Seoul, South Korea *These authors contributed equally to this work Background: Comorbidities have a serious impact on the frequent severe acute exacerbations (AEs) in patients with COPD. Previous studies have used the Charlson comorbidity index to represent a conglomerate of comorbidities; however, the respective contribution of each coexisting disease to the frequent severe AEs remains unclear.Methods: A retrospective, observational study was performed in 77 COPD patients who experienced severe AE between January 2012 and December 2014 and had at least 1-year follow-up period from the date of admission for severe AE. We explored the incidence of frequent severe AEs (≥2 severe AEs during 1-year period) in these patients and investigated COPD-related factors and comorbidities as potential risk factors of these exacerbations.Results: Out of 77 patients, 61 patients (79.2%) had at least one comorbidity. During a 1-year follow-up period, 29 patients (37.7%) experienced frequent severe AEs, approximately two-thirds (n=19) of which occurred within the first 90 days after admission. Compared with patients not experiencing frequent severe AEs, these patients were more likely to have poor lung function and receive home oxygen therapy and long-term oral steroids. In multiple logistic regression analysis, coexisting asthma (adjusted odds ratio [OR] =4.02, 95% confidence interval [CI] =1.30–12.46, P=0.016), home oxygen therapy (adjusted OR =9.39, 95% CI =1.60–55.30, P=0.013), and C-reactive protein (adjusted OR =1.09, 95% CI =1.01–1.19, P=0.036) were associated with frequent severe AEs. In addition, poor lung function, as measured by forced expiratory volume in 1 second (adjusted OR =0.16, 95% CI =0.04–0.70, P=0.015), was inversely associated with early (ie, within 90 days of admission) frequent severe AEs.Conclusion: Based on our study, among COPD-related comorbidities, coexisting asthma has a significant impact on the frequent severe AEs in COPD patients. Keywords: asthma, chronic obstructive pulmonary disease, comorbidity, exacerbation
- Published
- 2016
20. Factors influencing the frequency of visits by hypertensive patients to primary care physicians in Winnipeg.
- Author
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Roos, Noralou P., Carriere, Keumhee C., Friesen, David, Roos, N P, Carrière, K C, and Friesen, D
- Subjects
GENERAL practitioners ,HYPERTENSION ,PATIENTS ,PHYSICIAN-patient relations ,MEDICAL care ,STATISTICS - Abstract
Background: As part of a recent project focused on needs-based planning for generalist physicians, the authors documented the variety of practice styles of primary care physicians for managing patients with hypertension. They investigated the validity of various explanations for these different styles and the relative contributions of physician and patient characteristics to the rates at which hypertensive patients contact physicians.Methods: Retrospective descriptive study using regression analyses to simultaneously adjust for the influence of key patient and physician characteristics. Hypertensive patients in Winnipeg were identified using Manitoba physician claims data for fiscal years 1993/94 and 1994/95. Patients were included if they were 25 years of age or more and had at least one physician contact in both 1993/94 and 1994/95 during which hypertension was diagnosed. In addition, the primary care physician had to be the physician that the patient contacted most frequently in 1993/94 and 1994/95 and with whom she or he had at least 2 visits during this period. Only patients of family practitioners whose practice included at least 50 hypertensive patients were included.Results: To control for the effects of large samples and to validate the results, the authors conducted all analyses for half (6282) the sample of hypertensive patients who met the study criteria (12,563). A total of 132 primary care physicians who met the study criteria were identified. The patients made on average 9.3 ambulatory visits to physicians (both general practitioners and specialists) in 1994/95. Those who had more complex medical conditions (i.e., were formally referred to a specialist), those who had 3 or more serious medical problems and those who had been admitted to hospital made more visits to their primary care physician than those without these characteristics. After these and other key patient characteristics were controlled for, a primary care physician's patient recall rate in 1993/94 was strongly related to the number of visits his or her hypertensive patients made to all doctors for any reason in 1994/95. Physicians with high patient recall rates (i.e., who saw their hypertensive patients on average 8 or more times) in 1993/94 also had high recall rates in 1994/95.Interpretation: Because patient characteristics most strongly associated with high visit rates were those reflecting patient illness, policy measures aimed at patients (e.g., user fees and deinsurance) do not appear to be the appropriate policy tool for dealing with high visit rates. Given the influence of a physician's patient recall rate on patient visit patterns, physician profiling and feedback may prove more appropriate. [ABSTRACT FROM AUTHOR]- Published
- 1998
21. Inappropriate hospital use by patients receiving care for medical conditions: Targeting utilization review
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Decoster, C., Noralou Roos, Carrière, K. C., and Peterson, S.
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Adult ,Aged, 80 and over ,Adolescent ,Research ,Manitoba ,Length of Stay ,Middle Aged ,Health Services Misuse ,Hospitalization ,Utilization Review ,Indians, North American ,Humans ,Letters ,Aged ,Retrospective Studies - Abstract
OBJECTIVE: To describe characteristics associated with inappropriate hospital use by patients in Manitoba in order to help target concurrent utilization review. Utilization review was developed to reduce inappropriate hospital use but can be a very resource-intensive process. DESIGN: Retrospective chart review of a sample of adult patients who received care for medical conditions in a sample of Manitoba hospitals during the fiscal year 1993-94; assessment of patients at admission and for each day of stay with the use of a standardized set of objective, nondiagnosis-based criteria (InterQual). PATIENTS: A total of 3904 patients receiving care at 26 hospitals. OUTCOME MEASURES: Acute (appropriate) and nonacute (inappropriate) admissions and days of stay for adult patients receiving care for medical conditions. RESULTS: After 1 week, 53.2% of patients assessed as needing acute care at admission no longer required acute care. Patients 75 years of age or older consumed more than 50% of the days of stay, and 74.8% of these days of stay were inappropriate. Four diagnostic categories accounted for almost 60% of admissions and days, and more than 50% of those days of stay were inappropriate. Patients admitted through the emergency department were more likely to require acute care (60.9%) than others (41.7%). Patients who were Treaty Indians had a higher proportion of days of stay requiring acute care than others (45.9% v. 32.8%). Patients' income and day of the week on admission (weekday v. weekend) were not predictive factors of inappropriate use. CONCLUSION: Rather than conducting a utilization review for every patient, hospitals might garner more information by targeting patients receiving care for medical conditions with stays longer than 1 week, patients with nervous system, circulatory, respiratory or digestive diagnoses, elderly patients and patients not admitted through the emergency department.
22. Needs-based planning: The case of Manitoba
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Noralou Roos, Fransoo, R., Carrière, K. C., Fröhlich, N., Bogdanovic, B., Kirk, P., and Watanabe, M.
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Research ,health care economics and organizations - Abstract
OBJECTIVE: To illustrate the use of needs-based planning in the identification of physician surpluses and deficits and of resource misallocations within a provincial medical system at a time when provincial governments and medical associations across the country are faced with funding constraints for physician services. DESIGN: For each of 4 regions in Manitoba, the authors analysed residents' rates of physician visits (whether within the resident's own or another region). Residents' need for physician contact was estimated by means of a statistical analysis of the data on contacts in relation to age, sex and health-related indicators, and the rates of visits needed and actually made were compared. PARTICIPANTS: All Manitoba residents. OUTCOME MEASURES: Numbers of generalist physicians (general practitioners, family physicians, general internists and general pediatricians) needed to serve each region, and the extent of physician surplus and deficit in each region. RESULTS: There appeared to be a surplus of physicians in most of urban Manitoba but deficits in northern Manitoba and some parts of the rural south. General internists and general pediatricians in Winnipeg provide a significant part of the ambulatory care that is provided by general practitioners in other parts of the province. The provincial government currently spends more per resident to provide physician services in areas of physician surplus than in areas of physician deficit, although the patterns are inconsistent. CONCLUSIONS: Needs-based planning is possible. If provinces are intent on controlling physician numbers and expenditures, it makes sense to manage the implications of doing so.
23. Application of a new approach method to assess the hazard of complex legacy contaminated groundwater mixtures on fathead minnows in outdoor mesocosms.
- Author
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Gasque-Belz L, Carrière K, Humeniuk B, Park B, Colville C, Siciliano S, Hogan N, Weber L, Campbell P, Peters R, Hecker M, and Hanson M
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- Animals, Reproduction drug effects, Cyprinidae, Water Pollutants, Chemical analysis, Water Pollutants, Chemical toxicity, Groundwater chemistry, Environmental Monitoring methods
- Abstract
Assessing the environmental risks of contaminated groundwater presents significant challenges due to its often-complex chemical composition and to dynamic processes affecting exposure of organisms in receiving surface waters. The objective of this study was to characterize the effects of groundwater collected from a legacy contaminated industrial site, in fish under environmentally relevant conditions. A 21-day fish short-term reproduction assay was conducted in outdoor wetland mesocosms by exposing adult fathead minnows (Pimephales promelas) to graded concentrations of groundwater (1 %, 3 %, and 6 %). Offspring were held in mesocosms up to four days post-hatch to apply a new approach method (NAM), the EcoToxChip™, to explore whether traditional apical endpoints could be predicted using an alternative mechanistic approach. None of the groundwater concentrations used in this study were lethal to fish. There was greater cumulative number of eggs produced at the highest concentration of exposure. However, no abnormal histological appearance was observed in the liver and gonads of fish and no significant effect was observed in the relative expression of genes, tubercle counts, and erythrocyte micronuclei counts compared to the negative control. Food availability in the mesocosms was also assessed and the abundance of zooplankton increased in all groundwater-treated mesocosms. Fathead minnow findings are in contrast to those obtained from previous controlled laboratory studies that revealed significant genotoxicity, hepatotoxicity, and reprotoxicity of the same mixtures. Several factors could explain these observations, including the aging of groundwater in mesocosms before fish addition resulting in photo- and biodegradation and binding to sediments of toxic components. Our static exposure scenario likely underestimated realistic exposure scenarios where groundwater inflow to surface water is generally semi-continuous. Nevertheless, focused transcriptome analysis using EcoToxChips also observed greater toxicity during previous laboratory tests compared to mesocosm scenarios, and thus, our results support the use of this NAM in the ecological risk assessment of contaminated groundwater., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Laura Gasque-Belz reports financial support was provided by Natural Sciences and Engineering Research Council of Canada and the industry partner. The author (s) acknowledge the potential conflict of interest due to funding received from the industry partner and owner of the study site for this research project. However, for the present study they had no role in study design, in the collection, analysis and interpretation of data and in the writing of the report., (Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
- Published
- 2024
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24. The Unintended Psychosocial Consequences of GLP-1 Receptor Agonists for Children and Adolescents: A Call for More Research.
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Côté M, Carrière K, and Alberga AS
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- 2024
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25. Proof-of-concept testing of a mobile application-delivered mindfulness exercise for emotional eaters: RAIN delivered as a step-by-step image sequence.
- Author
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Carrière K, Siemers N, Thapar S, and Knäuper B
- Abstract
Background: Over fifty percent of individuals with overweight and obesity are emotional eaters. Emotional eating can be theorized as a conditioned response to eat for reasons that are not associated with physiological hunger. We conducted this proof-of-concept study to gather evidence that a mobile app that delivers a common non-meditative mindfulness exercise called RAIN, in a step-by-step image sequence can improve emotional eating and other outcomes over a 3-week period., Methods: Forty-nine Canadian adults who self reported as emotional eaters (mean age =30.7 years) were recruited through social media and participated in a workshop in which RAIN and its use on the app were introduced. Participants were asked to use the app every time that they experienced a non-homeostatic craving to eat for three weeks. Emotional eating, reactivity to food cravings, perceived loss of control around food, distress tolerance, and eating-specific mindfulness were assessed pre- and post-intervention., Results: Improvements on all outcomes were found (r-range, -0.58 to -0.28). The feasibility of the mobile application was demonstrated by a low attrition rate (8%), high user satisfaction, and strong app engagement metrics., Conclusions: The data provide proof-of-concept evidence that a mobile app that delivers a mindfulness exercise in a step-by-step image sequence has potential to be effective and thus identifies a new approach that may reduce emotional eating in an accessible and affordable manner., Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://mhealth.amegroups.com/article/view/10.21037/mhealth-23-56/coif). The authors received research funds from James McGill professorship through McGill University. The authors have no other conflicts of interest to declare., (2024 mHealth. All rights reserved.)
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- 2024
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26. Development and Validation of the Four Facet Mindful Eating Scale (FFaMES).
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Carrière K, Shireen SH, Siemers N, Preißner CE, Starr J, Falk C, and Knäuper B
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- Humans, Hunger, Reproducibility of Results, Surveys and Questionnaires, Feeding Behavior, Mindfulness
- Abstract
Objectives: Previous mindful eating scales stress the attentional domains of eating-specific mindfulness, such as present-moment attention to homeostatic cues of hunger and satiety while discounting other important domains such as non-judgment and decentering. The purpose of the series of studies was to develop and evaluate a multifaceted mindful eating scale that assesses several domains of eating-specific mindfulness., Methods: A multistep process was used to construct the Four Facet Mindful Eating Scale (FFaMES). Study 1 outlined the initial scale construction and the development of a novel item pool (N = 480). Study 2 examined the internal structure of the observed variables using exploratory analysis (N = 445) and confirmatory analysis in a separate sample (N = 445). Reliability and validity were assessed in Study 3 (N = 166)., Results: The final scale consists of 29 items with 4 factors: Non-Reactance, Non-Judgment, External Awareness, and Internal Awareness. The FFaMES demonstrated good internal consistency, retest reliability as well as preliminary convergent and divergent validity., Conclusions: Our findings provide reliability evidence and initial support for the construct validity of the FFaMES and the continued study of multiple facets of eating-specific mindfulness. Future research should continue to investigate the differential effects of various aspects of eating-specific mindfulness in the prevention and treatment of obesity and its comorbidities., (Copyright © 2021 Elsevier Ltd. All rights reserved.)
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- 2022
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27. The effects of if-then plans on weight loss: results of the 24-month follow-up of the McGill CHIP Healthy Weight Program randomized controlled trial.
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Knäuper B, Shireen H, Carrière K, Frayn M, Ivanova E, Xu Z, Lowensteyn I, Sadikaj G, Luszczynska A, and Grover S
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- Adult, Aged, Diet, Exercise, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prospective Studies, Time Factors, Weight Loss, Weight Reduction Programs
- Abstract
Background: Current evidence suggests that some of the most effective weight loss approaches are changes in dietary and physical activity behaviors through lifestyle modification programs. The Group Lifestyle Balance (GLB) program is a group-based behavior modification program aimed at changing diet and physical activity for weight loss. It was developed to be more cost-effective and easier to disseminate than its individually administered parent program, the Diabetes Prevention Program (DPP). However, the average weight loss following participation in the GLB is only approximately 3.5%, with low long-term weight loss maintenance., Purpose: We aimed to optimize the weight loss outcomes of the GLB to increase the efficacy already afforded by its cost-effectiveness and ease of dissemination. We did this by integrating the habit formation tool of if-then plans into the program. This program is called the enriched GLB or the McGill Comprehensive Health Improvement (CHIP) Healthy Weight Program. Results at 3 and 12 months of participation have already been published elsewhere. They showed no between-group differences between the standard and enriched GLB but higher weight loss in both groups compared to the DPP. This paper reports the long-term weight loss maintenance data following participation in the program., Methods: Of the 172 participants enrolled at the beginning of the study, data from 110 participants were available and analyzed at 24 months, i.e., 12 months after the end of the 12-month intervention., Results: No between-group difference in weight loss maintenance was observed. Pooled results showed a significant weight regain from 12 to 24 months, i.e., an average of 7.85 lbs. of the 20.36 lbs. lost. However, participants from both groups were still 12.51lbs or 6.13% lighter at 24 months than at baseline., Conclusion: If-then plans did not result in a higher percentage of weight loss at 24-month follow-up compared to the standard GLB. However, at 24 months, both groups did show a maintenance of a significant portion of the weight lost at the end of intervention., Trial Registration: ClinicalTrials.gov Identifier: NCT02008435, registered 6 December 2013.
- Published
- 2020
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28. The Effects of If-Then Plans on Weight Loss: Results of the McGill CHIP Healthy Weight Program Randomized Controlled Trial.
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Knäuper B, Carrière K, Frayn M, Ivanova E, Xu Z, Ames-Bull A, Islam F, Lowensteyn I, Sadikaj G, Luszczynska A, and Grover S
- Subjects
- Adolescent, Adult, Aged, Body Weight, Exercise physiology, Female, Habits, Humans, Life Style, Male, Middle Aged, Quebec, Treatment Outcome, Young Adult, Obesity therapy, Overweight therapy, Patient Care Planning standards, Patient-Centered Care methods, Weight Loss physiology, Weight Reduction Programs methods
- Abstract
Objective: The NIH-developed Diabetes Prevention Program (DPP) is successful in achieving clinically significant weight loss in individuals with overweight/obesity when delivered one-on-one. The group-based DPP is less effective, with average weight losses of only 3.5%. The objective of this study was to increase weight loss outcomes of the group-based DPP by integrating habit formation tools (i.e., if-then plans). This two-arm randomized controlled trial tested the efficacy of the habit formation-enhanced group-based DPP compared with the standard group-based DPP on changes in body weight (primary outcome). This study presents the 3- and 12-month results of this 24-month trial., Methods: A total of 208 participants were randomly assigned to the standard or enhanced DPP, and 172 participated. Participants were men and women with overweight/obesity who self-reported less than 200 min/wk of exercise., Results: Both groups achieved high weight losses at 3 (5.76%) and 12 (9.98%) months, with no differences between groups (χ
2 < 1). Both groups improved in blood pressure and physical activity., Conclusions: If-then plans did not result in higher weight loss. Both program versions resulted in higher weight loss than the group-based DPP. This may suggest that cognitive behavioral therapy skills of the coaches (clinical psychology doctoral students) was a key factor in treatment outcome., (© 2018 The Obesity Society.)- Published
- 2018
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29. Daily Mindful Responding Mediates the Effect of Meditation Practice on Stress and Mood: The Role of Practice Duration and Adherence.
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Lacaille J, Sadikaj G, Nishioka M, Carrière K, Flanders J, and Knäuper B
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- Adult, Female, Humans, Male, Middle Aged, Affect physiology, Meditation methods, Mindfulness methods, Outcome and Process Assessment, Health Care, Patient Compliance psychology, Stress, Psychological therapy
- Abstract
Objective: Although meditation practice is an important component of many mindfulness-based interventions (MBIs), empirical findings of its effects on psychological functioning are mixed and the mechanisms for the effects remain unclear. Responding with mindfulness (i.e., returning one's attention back to a nonjudgmental, present-oriented awareness) is a fundamental skill practiced in meditations. With repeated meditation practice, this skill is thought to become internalized and be applied to one's daily life. We thus hypothesized that the extent to which individuals responded to daily events with mindfulness would mediate the effects of meditation practice (instance, duration, and adherence to instructions) on psychological well-being., Method: Using a daily diary methodology, we tracked the meditation practice, use of mindful responding during the day, and psychological outcomes (perceived stress, negative and positive affect) of 117 mindfulness-based stress reduction program participants., Results: We found that on days when participants meditated, they responded with greater mindfulness to daily events, which accounted for the beneficial effects of meditating on psychological outcomes. Furthermore, findings suggest that on meditation days, longer and more closely adhered meditation practices were independently associated with increases in mindful responding, which in turn were associated with better psychological outcomes., Conclusion: These results suggest that regular, longer, and more closely adhered meditation practice is an important component of MBIs, in part because it leads to responding more mindfully in daily life, which promotes well-being., (© 2017 Wiley Periodicals, Inc.)
- Published
- 2018
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30. Effectiveness of traditional meditation retreats: A systematic review and meta-analysis.
- Author
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Khoury B, Knäuper B, Schlosser M, Carrière K, and Chiesa A
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- Humans, Meditation psychology, Psychology, Meditation methods
- Abstract
Background: An increasing number of studies are investigating traditional meditation retreats. Very little, however, is known about their effectiveness., Objective: To evaluate the effectiveness of meditation retreats on improving psychological outcomes in general population., Data Sources: A systematic review of studies published in journals or as dissertations in PSYCINFO, PUBMED, CINAHL or Web of Science from the first available date until October 22, 2016., Review Methods: A total of 20 papers (21 studies, N=2912) were included., Results: Effect-size estimates of outcomes combined suggested that traditional meditation retreats are moderately effective in pre-post analyses (n=19; Hedge's g=0.45; 95% CI [0.35, 0.54], p<0.00001) and in analyses comparing retreats to controls (n=14; Hedge's g=0.49; 95% CI [0.36, 0.61], p<0.00001). Results were maintained at follow-up. No differences were observed between meditation styles. Results suggested large effects on measures of anxiety, depression and stress, and moderate effects on measures of emotional regulation and quality of life. As to potential mechanisms of actions, results showed large effects on measures of mindfulness and compassion, and moderate effects on measures of acceptance. In addition, changes in mindfulness levels strongly moderated clinical effect sizes. However, heterogeneity was significant among trials, probably due to differences in study designs, types and duration of the retreats and assessed outcomes, limiting therefore the implications of the results., Conclusion: Meditation retreats are moderately to largely effective in reducing depression, anxiety, stress and in ameliorating the quality of life of participants., (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Published
- 2017
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31. How aging affects self-reports.
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Knäuper B, Carrière K, Chamandy M, Xu Z, Schwarz N, and Rosen NO
- Abstract
A lot of information used in aging research relies on self-reports. Surveys or questionnaires are used to assess quality of life, attitudes toward aging, experiences of aging, subjective well-being, symptomatology, health behaviors, financial information, medication adherence, etc. Growing evidence suggests that older and younger respondents are differentially affected by questionnaire features and the cognitive tasks that question answering pose. This research has shown that age-related changes in cognitive and communicative functioning can lead to age-related differences in self-reports that are erroneously interpreted as real age differences in attitudes and behaviors. The current review highlights how the processes underlying respondents' self-report change as a function of respondents' age; it updates our previous reviews of this literature.
- Published
- 2016
- Full Text
- View/download PDF
32. The role of proxy information in missing data analysis.
- Author
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Huang R, Liang Y, and Carrière KC
- Subjects
- Canada, Clinical Trials as Topic statistics & numerical data, Data Interpretation, Statistical, Proxy statistics & numerical data
- Abstract
This article investigates the role of proxy data in dealing with the common problem of missing data in clinical trials using repeated measures designs. In an effort to avoid the missing data situation, some proxy information can be gathered. The question is how to treat proxy information, that is, is it always better to utilize proxy information when there are missing data? A model for repeated measures data with missing values is considered and a strategy for utilizing proxy information is developed. Then, simulations are used to compare the power of a test using proxy to simply utilizing all available data. It is concluded that using proxy information can be a useful alternative when such information is available. The implications for various clinical designs are also considered and a data collection strategy for efficiently estimating parameters is suggested.
- Published
- 2005
- Full Text
- View/download PDF
33. Variations in treatment of femoral neck fractures in Alberta.
- Author
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Cree M, Yang Q, Scharfenberger A, Johnson D, and Carrière KC
- Subjects
- Aged, Aged, 80 and over, Alberta epidemiology, Arthroplasty, Replacement, Hip statistics & numerical data, Cohort Studies, Comorbidity, Female, Femoral Neck Fractures epidemiology, Fracture Fixation, Internal statistics & numerical data, Hospital Mortality, Hospitals statistics & numerical data, Humans, Length of Stay statistics & numerical data, Logistic Models, Male, Retrospective Studies, Femoral Neck Fractures surgery, Practice Patterns, Physicians' statistics & numerical data
- Abstract
Objectives: To examine, in the province of Alberta, temporal trends, regional variations in treatment options and in-hospital death rates after a femoral neck fracture., Design: A retrospective cohort study., Patients: Six years' data were abstracted from the Alberta Morbidity File, the Alberta Health Stakeholder File and the Alberta Health Care Claims File. Patients were included if they were Alberta residents, aged 65 years or older, had sustained a femoral neck fracture and had undergone internal fixation, hemiarthroplasty or total hip arthroplasty., Main Outcome Measures: Death rates, arthroplasty rates and hospital stay., Results: In-hospital death rates were similar across hospitals, with risks being higher for men, patients aged 80 years or older and those with more comorbid conditions. Arthroplasty rates varied from 58% to 77% among hospitals, and hospital stays associated with arthroplasty were significantly longer than those associated with internal fixation. The chance of undergoing arthroplasty varied from hospital to hospital by gender and by the number of comorbid conditions., Conclusion: Regional variations suggest lack of agreement among Alberta's surgeons as to how best to treat femoral neck fractures.
- Published
- 2002
34. Factors influencing the frequency of visits by hypertensive patients to primary care physicians in Winnipeg.
- Author
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Roos NP, Carrière KC, and Friesen D
- Subjects
- Adult, Aged, Aged, 80 and over, Female, Health Services Needs and Demand, Health Status, Hospitalization statistics & numerical data, Humans, Income classification, Male, Manitoba, Mental Recall, Middle Aged, Registries, Regression Analysis, Reproducibility of Results, Retrospective Studies, Urban Population, Utilization Review, Family Practice statistics & numerical data, Hypertension therapy, Office Visits statistics & numerical data, Practice Patterns, Physicians' statistics & numerical data
- Abstract
Background: As part of a recent project focused on needs-based planning for generalist physicians, the authors documented the variety of practice styles of primary care physicians for managing patients with hypertension. They investigated the validity of various explanations for these different styles and the relative contributions of physician and patient characteristics to the rates at which hypertensive patients contact physicians., Methods: Retrospective descriptive study using regression analyses to simultaneously adjust for the influence of key patient and physician characteristics. Hypertensive patients in Winnipeg were identified using Manitoba physician claims data for fiscal years 1993/94 and 1994/95. Patients were included if they were 25 years of age or more and had at least one physician contact in both 1993/94 and 1994/95 during which hypertension was diagnosed. In addition, the primary care physician had to be the physician that the patient contacted most frequently in 1993/94 and 1994/95 and with whom she or he had at least 2 visits during this period. Only patients of family practitioners whose practice included at least 50 hypertensive patients were included., Results: To control for the effects of large samples and to validate the results, the authors conducted all analyses for half (6282) the sample of hypertensive patients who met the study criteria (12,563). A total of 132 primary care physicians who met the study criteria were identified. The patients made on average 9.3 ambulatory visits to physicians (both general practitioners and specialists) in 1994/95. Those who had more complex medical conditions (i.e., were formally referred to a specialist), those who had 3 or more serious medical problems and those who had been admitted to hospital made more visits to their primary care physician than those without these characteristics. After these and other key patient characteristics were controlled for, a primary care physician's patient recall rate in 1993/94 was strongly related to the number of visits his or her hypertensive patients made to all doctors for any reason in 1994/95. Physicians with high patient recall rates (i.e., who saw their hypertensive patients on average 8 or more times) in 1993/94 also had high recall rates in 1994/95., Interpretation: Because patient characteristics most strongly associated with high visit rates were those reflecting patient illness, policy measures aimed at patients (e.g., user fees and deinsurance) do not appear to be the appropriate policy tool for dealing with high visit rates. Given the influence of a physician's patient recall rate on patient visit patterns, physician profiling and feedback may prove more appropriate.
- Published
- 1998
35. Family members' care expectations, care perceptions, and satisfaction with advanced cancer care: results of a multi-site pilot study.
- Author
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Kristjanson LJ, Leis A, Koop PM, Carrière KC, and Mueller B
- Subjects
- Aged, Alberta, Female, Humans, Linear Models, Male, Manitoba, Middle Aged, Multivariate Analysis, Pilot Projects, Reproducibility of Results, Saskatchewan, Caregivers psychology, Consumer Behavior, Neoplasms nursing, Palliative Care, Psychometrics
- Abstract
Psychometric properties of assessment tools designed for use with English-speaking family members of advanced cancer patients in different care settings and different geographic locations were evaluated in this study. The robustness of the theoretical framework guiding the study and the factors identified with care satisfaction were also tested. Seventy-two family members drawn equally from medical hospital units, palliative care units, and home care programs in Alberta, Saskatchewan, and Manitoba participated. Instruments used included the F-Care Expectations Scale, F-Care Perceptions Scale, FAMCARE Scale, and the General Functioning Scale of the Family Assessment Device. All four tools yielded acceptable reliability estimates. Discrepancy theory predicted family care satisfaction in a highly significant manner (p < 0.0001). Family members of patients who had been diagnosed for longer than two years had more positive perceptions of palliative care than did family members of patients diagnosed for less than two years (p = 0.05). Older family members reported better family functioning than younger family members (p < 0.001). Spouses reported less discrepancy between care expectations and perceptions than did other relatives (p < 0.05).
- Published
- 1997
36. Needs-based planning: the case of Manitoba.
- Author
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Roos NP, Fransoo R, Carrière KC, Frohlich N, Bogdanovic B, Kirk P, and Watanabe M
- Subjects
- Health Services Research, Health Status Indicators, Humans, Manitoba, Rural Health, Socioeconomic Factors, Urban Health, Workload, Health Resources, Health Services Needs and Demand organization & administration, Physicians, Family statistics & numerical data, Physicians, Family supply & distribution, Regional Health Planning organization & administration
- Abstract
Objective: To illustrate the use of needs-based planning in the identification of physician surpluses and deficits and of resource misallocations within a provincial medical system at a time when provincial governments and medical associations across the country are faced with funding constraints for physician services., Design: For each of 4 regions in Manitoba, the authors analysed residents' rates of physician visits (whether within the resident's own or another region). Residents' need for physician contact was estimated by means of a statistical analysis of the data on contacts in relation to age, sex and health-related indicators, and the rates of visits needed and actually made were compared., Participants: All Manitoba residents., Outcome Measures: Numbers of generalist physicians (general practitioners, family physicians, general internists and general pediatricians) needed to serve each region, and the extent of physician surplus and deficit in each region., Results: There appeared to be a surplus of physicians in most of urban Manitoba but deficits in northern Manitoba and some parts of the rural south. General internists and general pediatricians in Winnipeg provide a significant part of the ambulatory care that is provided by general practitioners in other parts of the province. The provincial government currently spends more per resident to provide physician services in areas of physician surplus than in areas of physician deficit, although the patterns are inconsistent., Conclusions: Needs-based planning is possible. If provinces are intent on controlling physician numbers and expenditures, it makes sense to manage the implications of doing so.
- Published
- 1997
37. Inappropriate hospital use by patients receiving care for medical conditions: targeting utilization review.
- Author
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DeCoster C, Roos NP, Carrière KC, and Peterson S
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Humans, Indians, North American statistics & numerical data, Length of Stay statistics & numerical data, Manitoba, Middle Aged, Retrospective Studies, Health Services Misuse, Hospitalization statistics & numerical data, Utilization Review
- Abstract
Objective: To describe characteristics associated with inappropriate hospital use by patients in Manitoba in order to help target concurrent utilization review. Utilization review was developed to reduce inappropriate hospital use but can be a very resource-intensive process., Design: Retrospective chart review of a sample of adult patients who received care for medical conditions in a sample of Manitoba hospitals during the fiscal year 1993-94; assessment of patients at admission and for each day of stay with the use of a standardized set of objective, nondiagnosis-based criteria (InterQual)., Patients: A total of 3904 patients receiving care at 26 hospitals., Outcome Measures: Acute (appropriate) and nonacute (inappropriate) admissions and days of stay for adult patients receiving care for medical conditions., Results: After 1 week, 53.2% of patients assessed as needing acute care at admission no longer required acute care. Patients 75 years of age or older consumed more than 50% of the days of stay, and 74.8% of these days of stay were inappropriate. Four diagnostic categories accounted for almost 60% of admissions and days, and more than 50% of those days of stay were inappropriate. Patients admitted through the emergency department were more likely to require acute care (60.9%) than others (41.7%). Patients who were Treaty Indians had a higher proportion of days of stay requiring acute care than others (45.9% v. 32.8%). Patients' income and day of the week on admission (weekday v. weekend) were not predictive factors of inappropriate use., Conclusion: Rather than conducting a utilization review for every patient, hospitals might garner more information by targeting patients receiving care for medical conditions with stays longer than 1 week, patients with nervous system, circulatory, respiratory or digestive diagnoses, elderly patients and patients not admitted through the emergency department.
- Published
- 1997
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