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9. From Cyclic Nanorings to Single-Walled Carbon Nanotubes: Disclosing the Evolution of their Electronic Structure with the Help of Theoretical Methods

Author

Pérez-Guardiola, A., Ortiz-Cano, R., Sandoval-Salinas, M. E., Fernández-Rossier, J., Casanova, D., Pérez-Jiménez, A. J., and Sancho-García, J. C.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

We systematically investigate the relationships between structural and electronic effects of finite size zigzag or armchair carbon nanotubes of various diameters and lengths, starting from a molecular template of varying shape and diameter, i.e. cyclic oligoacene or oligophenacene molecules, and disclosing how adding layers and/or end-caps (i.e. hemi-fullerenes) can modify their (poly)radicaloid nature. We mostly used tight-binding and finite-temperature density-based methods, the former providing a simple but intuitive picture about their electronic structure, and the latter dealing effectively with strong correlation effects by relying on a fractional occupation number weighted electron density (\rho FOD ), with additional RAS-SF calculations backing up the latter results. We also explore how minor structural modifications of nanotube end-caps might influence the results, showing that topology, together with the chemical nature of the systems, is pivotal for the understanding of the electronic properties of these and other related systems.

Published
2018

15. Arm reconstruction

Author

Witters, M., Jaloux, C., Abellan-Lopez, M., Kachouch, N., Mayoly, A., Philandrianos, C., Bertrand, B., Casanova, D., and Legre, R.

Published
2020
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16. Inferring maps of forces inside cell membrane microdomains

Author

Masson, J. -B., Casanova, D., Tuerkcan, S., Voisinne, G., Popoff, M. R., Vergassola, M., and Alexandrou, A.

Subjects
Physics - Biological Physics, Quantitative Biology - Quantitative Methods
Abstract

Mapping of the forces on biomolecules in cell membranes has spurred the development of effective labels, e.g. organic fluorophores and nanoparticles, to track trajectories of single biomolecules. Standard methods use particular statistics, namely the mean square displacement, to analyze the underlying dynamics. Here, we introduce general inference methods to fully exploit information in the experimental trajectories, providing sharp estimates of the forces and the diffusion coefficients in membrane microdomains. Rapid and reliable convergence of the inference scheme is demonstrated on trajectories generated numerically. The method is then applied to infer forces and potentials acting on the receptor of the $\epsilon$-toxin labeled by lanthanide-ion nanoparticles. Our scheme is applicable to any labeled biomolecule and results show show its general relevance for membrane compartmentation., Comment: 6 pages, 4 figures

Published
2015
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17. Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

Author

Bengueddach, A., Tidjane, A., Tabeti, B., Behilil, C., Boudjenan-Serradj, N., Bensafir, S., Meharzi, S. E. I., Aissat, A., Ghouali, A. K., Larabi, K., Riffi, O., Kacimi, S. E. O., Mesli, S. N., Rezoug, W., Mitidieri, A., Jose, A., Pablo, C., Rodriguez, C. A., Panettiere, M. F., Barbalace, N., Juan, T., Lucena, J., Houdin, A., Fernandez, E., Lococo, J., Pedro, L., Loban, M., Vecchio, P., Grinblat, A., Carrie, A., Veracierto, F., Santillan, M., Napolitano, M., Avellaneda, N., Rosa, S. L., Gonzalez, C. M., Ferro, E., Munoz, J. P., Ventorutti, T., Cabrera, C., Carrizo, C., Mospane, C., Leiro, F., Espino, J., Trama, M., Bianchi, R., Potolicchio, A., Dindri, F., Buey, L., Lucas, N., Catalano, P., Astilleta, R., Quiroga, Y., Chwat, C., Valli, D., Alexandre, F., Martres, G., Rosato, G., Lemme, G., Romero, V., Doniquian, A. M., Pachajoa, D. A. P., Llahi, F., Fiorenza, J. M., Parodi, M., Ocana, N., Gallardo, A., Valenzuela, A., Perriello, J., Nador, R., Fermani, C., Garay, L., Blanco, P., Villalobos, S., Posner, F., Vieyra, N., Fiorito, P., Ciabattari, P., Kort, C. D., Daryanani, D., Smit, J., Gosselink, M. P., Janssen, N., Feiss, A., Lee, C. H. A., Taylor, D., Edington, J., Chen, N., Ong, W. M., Aigner, F., Moitzi, G., Gemes, G., Braumille, M., Mitteregger, M., Gerald, S., Uranitsch, S., Belarmino, A., Waha, J., Kahn, J., Treiber, M., Schemmer, P., Mikalauskas, S., Ibrahimli, A., Samadov, E., Orujova, E., Namazov, I., Alikhanli, J., Asgarov, M., Kutkut, A., Almahmeed, E., Aljawder, H., Juma, I., Johnston, K., Saeed, M. F., Khairi, S., Matovic, E., Omerasevic, M., Delibegovic, S., Hodzic, S., Rudell, A. G., Fuzari, J., Farah, J. F., Nadal, L. R. M., Dos Santos, M. B. A., Lupinacci, R. A., Pereira, T. S., Sete, A. D. S., Filho, A. L., De Souza Pires, B. L., Queiroz, F. L. D., Amaral, H. A. T., Dos Santos, M. A. M., De Miranda Silvestre, S. C., Hanan, B., Reis, C., Cassia, G., Luz, M. D., Delgado, M., Campanati, R., Silva, R., Bomfa-Barbosa, A., Alves, B. C., Costa, B. X. M., Cortes, B. G. W., Lemos, F. H. T., Arreguy-Borges, K., Silva, T. B., Assis, A., Freitas, A. H., Rezende, D., Silva, H., Alvarenga, I., Cascais, R., Silva, T., Santos, G., Pinto, H., Silva, I., Leite, L., Massahud, M., Meyer, M., Tiburcio, R., Martinez, C. A. R., Espinha, D. R., Marson, F. A. L., De Oliveira Goes, I. A., De Souza Artioli, L. M., Boschiero, M. N., Takahashi, C. Y., Oliveira, F. G. D., Lyra, H. F., De Oliveira, J. C. C., Santos, J. M. D., Gerber, M. T., Erdmann, T. R., Barbosa, A., Fernandes, A., Junior, A. N., Junior, H. M., Moreira, J., Ribeiro, M., Moreira, P., Carvalho, A., Santos, B., Fidelis, F., Cruz, I., Codes, L., Aibe, R., Boudoux, S., Favacho, B. C., Pinto, F., Gava, G., Pivati, I. R., Vilain, L. F., Kim, N., Nunes, R. L., Dimitrov, D., Peneva, K., Karamanliev, M., Dimitrova, S., Ivanov, T., Atanasov, B., Dzharov, G., Shtereva, M., Slavchev, M., Belev, N., Krastev, P., Arabadzhiev, A., Tonova, D., Tzoneva, D., Sokolov, M., Gribnev, P., Maslyankov, S., Pavlov, V., Bakmaz, B., Dijan, E., Coza, I., Mihanovic, J., Kucic, J., Sulen, N., Katusic, Z., Hudacek, K., Farkasova, M., Markova, M., Grolich, T., Kala, Z., Pazdirek, F., Hoch, J., Filipova, L., Kocian, P., Prikryl, P., Hogn, A., Moller, B., Slot, D. K., Baelum, J. K., Cour, K. L., Ellebaek, M. B., Eriksen, N. D., Mahmoud, A., Abdellatif, A., Nafea, A., Ewedah, M., Soliman, M., Yakout, N., Argawy, O., Sallam, I., Kamel, I., Sherif, M., Ashmawy, S., Ali, A., Saad, M., Ahmed, M., Mohamed, M., Mohamed, N., Mahmoud, S., Rashed, A. M., Abd-Errazik, M. A., Ammar, M. A., Mohammed, R., Ebrahem, A., Aal, A. A. E., Abdou, K., Wagdy, M., Qassem, M., Taha, M., El-Wafa, Y. A., Shehta, A., Metwally, A. E., Hamed, H., Ali, M. A., Elrefai, M., Sorogy, M. E., Abdelkhalek, M., Ragab, A., Refky, B., Metwally, I. H., Kamal, M., Zuhdy, M., Shetiwy, M., Sakr, A., Elfallal, A., Elfeki, H., Eldakroury, I., Elbahrawy, K., Mostafa, M., Emile, S., Tessema, A., Tasew, A., Gezahegn, H., Bekele, K., Belay, M., Gudisa, Z., Teferu, Z., Vayrynen, A., Kechagias, A., Turunen, A., Katunin, J., Parhiala, M., Pengerma, P., Lahti, P., Carpelan, A., Vihervaara, H., Huhtinen, H., Pasonen, J., Heino, R., Pakarinen, S., Falenius, V., Pinard, B., Nobile, C., Duchalais, E., Drissi, F., Meurette, G., Podevin, J., Lepenndu, M., Hoetzel, A., Jud, A., Jauch, D., Stefan, F. -F., Neeff, H., Holzner, P., Nguyen, P., Ryl, A., Kehl, F., Pullig, F., Baral, J., Munch, S., Futterer, C., Reissfelder, C., Sandra-Petrescu, F., Herrle, F., Hardt, J., Lamm, L., Seyfried, S., Gharbi, A., Aydin, F., Stavrou, G., Sperber, J., Deken, J. D., Schwarzkopf, K., Widyaningsih, R., Polidorou, A., Mpakas, A., Tokidis, E., Loun, L., Petropoulou, T., Balalis, D., Korkolis, D., Manatakis, D., Assimakopoulou, E., Bourazani, M., Gklavas, A., Kalamara, E., Papaconstantinou, I., Theodoraki, K., Chardalias, L., Konstadoulakis, M., Theodosopoulos, T., Soulioti, E., Kavezou, F., Filippou, J., Papadoliopoulou, M., Michalopoulos, N., Vassiliu, P., Sidiropoulos, T., Charakopoulou, A., Panagiotou, A., Bouchagier, K., Kokkinakis, K., Lambridi, E., Psarologos, M., Maria, S., Giannaraki, S., Kapiris, S., Triantafyllou, A., Theodoropoulos, C., Matthaiou, G., Westzaan, N., Etelka, S., Triantafyllou, T., Schizas, D., Mpaili, E., Karydakis, L., Mpoura, M., Danassi, D., Karavokyros, I., Dimitriou, N., Livanou, X., Kikira, A., Tsourouflis, G., Tomara, N. -K., Nikiteas, N., Dorovinis, P., Garoufalia, Z., Tsiotos, G., Stamou, K., Kocka, N., Ballian, N., Kalakonas, S., Athanasakis, E., Chrysos, E., Xynos, E., Tsiaoussis, J., Papadaki, K., Xenaki, S., Nyktari, V., Sarakatsianou, C., Bompou, E., Arnaoutoglou, E., Tzovaras, G., Baloyiannis, I., Mamaloudis, I., Perivoliotis, K., Apostolidi, E., Mulita, F., Karpetas, G., Maroulis, I., Vailas, M., Petra, A., Kontis, E., Kaouras, E., Katsaros, I., Katsiaras, L., Manikis, P., Papadopoulou, T., Papadopoulos, A., Manioti, E., Zeringa, G., Katsinelis, I., Mouzakis, O., Kouki, P., Nikolaou, V., Marinis, A., Alexopoulou, K., Papadaki, M., Vederaki, S. -A., Samara, A., Giakoustidis, D., Christodoulidis, G., Bareka, M., Chatzikomnitsa, P., Tsigara, S., Papadopoulos, V., Zarzava, E., Anestiadou, E., Lydia, L., Apostolakidou, M., Ioannidis, O., Simeonidis, S., Mpitsianis, S., Futaba, K., Tam, P. T. H., Ng, S. S. M., Lau, V. N. M., Tse, W. K., Banky, B., Dolhai, E., Horvath, E., Golub, J., Marton, J., Lakatos, L., Susztak, N., Maurya, A. P., Kumawat, H., Saxena, P., Lather, R., Waindeskar, V., Khanduri, A., Goyal, L., Gupta, R., Singh, S., Saksena, A. R., Rayani, B. K., Kasula, J., Raju, K., Shah, M. M., Thammineedi, S. R., Patnaik, S. C., Rathod, D., Poonia, D. R., Vishnoi, J. R., Sharma, N., Byshetty, R., Yadav, R. K., Misra, S., Dhali, A., Dhali, G. K., Biswas, J., Ray, S., Ghose, T., Pipara, A., Singh, H. M., Roy, M. K., Desai, N., Thambudorai, R., Ishwarappagol, V., Chaturvedi, A., Verma, D., Akhtar, N., Gupta, S., Rajan, S., Tiwari, T., Kumar, V., Mahajan, A., Jain, D., Liddle, D., Jyoti, J., Haque, P. D., Jain, R., Veetil, S. K., Prem, W., Lakshminarayana, B., Veerabhadrappa, B., Poojary, P. H., Bhat, R. R. K., Mathew, S., Gupta, L., Bains, L. H., Bains, L., Kumar, M., Singh, N., Lal, P., Sharma, A., Kumar, A., Garg, L., Aggarwal, M., Jakhar, R., Bose, B., Huda, F., Thakur, N., Dhar, P., Seenivasagam, K., Prakash, S., Chaudhari, A., Shukla, A., Mahakalkar, C., Saxena, G., Mahuli, K., Kaple, M., Kshirsagar, S., Mehraj, A., Parray, F., Aziz, G., Chowdri, N., Wani, R. F., Gurcoo, S., Shah, Z., Polamreddy, B. M., Madhavan, S., Subbarayan, S., Vino, S., Aravindan, U., George, G., Harikumar, C. K., Yadev, I. P., Chisthi, M., Revathy, P. S., Sreekumar, R. C., Vijayan, V., Theodore, B., Victor, C., Jesudason, M. R., Arulappan, N., Philip, R., Mittal, R., Durai, S., Creavin, B., Cullinane, C., Davis, C., Flynn, C., Liam, D., Cooke, F., Earley, H., Mccullough, P., Neary, P., Hamilton, V., Trani, A. D., Conversano, I., Cianci, P., Petta, R., Picciariello, A., Altomare, D. F., Martines, G., Grasso, S., Moffa, S., Papagni, V., Zanoni, A., Belvedere, A., Romano, A., Croce, G. D., Tanzanu, M., Rottoli, M., Cardelli, S., Lauro, A., Sartarelli, L., Binetti, M., Cervellera, M., Tonini, V., Sanna, B., Pusceddu, E., Runfola, M., Manunza, R., Pisanu, A., Cois, A., Frongia, F., Esposito, G., Podda, M., Mura, P., Cutelle, C., Ammerata, G., Sena, G., Pignataro, M., Scozzafava, M., Mazza, M., Bruni, A., Curro, G., Hila, J., Ammendola, M., Curcio, S., Signorelli, V., Marano, A., Sasia, D., Borghi, F., Giuffrida, M. C., Bonardello, M., Palmisano, S., Testa, V., Porta, A., Scaltrini, F., Iacob, G., Gaspa, I., Guatteri, L., Coladonato, M., Zapparoli, A., Pesce, A., Feo, C. V., Pindozzi, F., Bigoni, I., Torchiaro, M., Fabbri, N., Cianchi, F., Staderini, F., Elena, F., Coratti, F., Barbato, G., Fortuna, L., Romagnoli, S., Bergamini, C., Villa, G., Cecchini, I., Martellucci, J., Izzo, M., Trafeli, M., Scheiterle, M., Manoocheehri, F., Cagnazzo, F., Spampinato, M. G., Adam, N., Depalma, N., D'Ugo, S., Garritano, S., Mazzeo, C., Cucinotta, E., Melita, F., Viscosi, F., Fleres, F., Biondo, S. A., Tripodi, V. F., Spinelli, A., Foppa, C., Greco, M., Sacchi, M., Carvello, M., Deac, V., Laurenti, V., Frontali, A., Zappone, A., Cammarata, F., Colombo, F., Ferrario, L., Curra, M. C., Danelli, P., Vignali, A., Umberto, C., Mastriale, F., Riccardo, R., Turi, S., Elmore, U., Galimberti, A., Ceretti, A. P., Vespo, D., Opocher, E., Longhi, M., Mariani, N. M., Flandoli, C., Ciulli, C., Vaira, G., Ripamonti, L., Cigagna, L., Oldani, M., Tamini, N., Palumbo, A., Castaldi, A., Antropoli, C., Rupealta, N., Palmiero, N., Donatiello, V., Novi, A., Cappiello, A., Bianco, F., Luca, M. D., Incollingo, P., Esposito, R., Gili, S., Aprea, G., Simone, G. D., Palomba, G., Capuano, M., Basile, R., Tropeano, F. P., Luglio, G., Pagano, G., Palma, G. D. D., Cricri, M., Milone, M., Manigrasso, M. E., Anoldo, P., D'Angelo, S., Marzella, A., Scotto, B., Cuneo, D., Ascari, F., Giulino, G., Varoli, M., Laquatra, N., Fortunato, C., Marino, F., Perrone, F., Pace, M., Convertini, O., Boccia, G., Raiano, G., Nuzzo, M. M. D., Calabria, M., Peltrini, R., Castiglioni, S., Bracale, U., Cervone, C., Rega, D., Caliendo, D., Benetti, E., Delrio, P., Guarino, R., Franciscis, S. D., Coppolino, F., Romano, F. M., Selvaggi, F., Pellino, G., Sciaudone, G., Selvaggi, L., Stefano, M. D., Resendiz, A., Carosso, F., Degiuli, M., Salusso, P., Reddavid, R., Benetti, S., Callari, C., Miceli, D. D., Pardo, D., Sabatino, G., Licari, L., Lirosi, M. C., Sorce, V., Peri, A., Mori, A., Pugliese, L., Filardo, M., Nuccio, P., Dominioni, T., Giuseppina, F., Angelo, F., Raffaele, G., Michele, M., Roberto, P., Mondini, A., Muratore, A., Valentino, C., Calabro, M., Danna, R., Cremonini, C., Sbarbaro, C., Tartaglia, D., Coccolini, F., Chiarugi, M., Musetti, S., Pagani, S., Neri, C. M., Leoni, C., Rossi, E., Randisi, E., Puccini, M., Buccianti, P., Balestri, R., Vasale, A. O., Crescentini, G., Ranieri, G., Sinibaldi, G. I., Biondi, Alberto, Sanesi, A. P., Vacca, C., Lorenzon, Laura, Sollazzi, Liliana, Persiani, Roberto, Pezzuto, Roberto, Ferroni, A. F., Stipa, F., Volturo, L., Moretti, M., Tierno, S. M., Marina, S., Mingoli, A., Fiori, E., Pugliese, F., Brachini, G., Carta, G., Sapienza, P., Lapolla, P., Mazzotta, E., Carannante, F., Capolupo, G. T., Masciana, G., Sica, I., Caricato, M., Antonelli, S., Fiume, D., Spoletini, D., Lisi, G., Carlini, M., Menduni, V., Arturi, A., Proietto, B., Lucia, C. D., Baldi, C., Passantino, D. G., Romeo, G., Paola, M. D., Sensi, B., Sica, G., Siragusa, L., Dauri, M., Franceschill, M., Campanelli, M., Bellato, V., Porcu, A., Garau, A. G. G., Masala, M. L., Oggianu, S., Tedde, T., Perra, T., Pazzola, V., Venezia, D. F., Roviello, F., Giacomini, G., Carbone, L., Marano, L., Verre, L., Marano, M., Ciccarese, A. A., Bagnardi, F., Shahu, J., Siciliano, W., Iacomino, A., Armellin, C., Marson, F., Zanus, G., Santoro, G. A., Paoli, M. D., Grossi, U., Sekimoto, M., Kobayashi, T., Horiguchi, A., Koike, D., Yonekura, H., Kato, H., Yoshino, K., Arakawa, S., Asano, Y., Alawneh, F., Rajab, I., Ramadan, M., Masri, M. A., Qaisi, M. A., Alsamneh, M., Mubaidin, O., Al-Jarrah, A., Ababneh, H., Khdair, K., Tawarh, T., Sabri, W., Arida, Z. A., Dzhumabekov, B., Klyshbayeva, D., Fakhradiyev, I., Ispbayeva, K., Nadyrov, M., Tanabayeva, S., Saliev, T., Jumanov, A., Aitbaeva, A., Arynov, A., Kulimbet, M., Maulenov, N., Dushimova, Z., Park, E. J., Kim, H., Kang, J., Baik, S. H., Song, Y., Kwak, H. D., Kim, J., Son, J. H., Chung, J. S., Lee, H., Baek, J. -H., Nam, K. H., Lee, W. -S., Jeon, Y., Kim, C. W., Park, S. -E., Lee, S. -H., Son, G. M., Ahn, H. M., Lee, I. Y., Kim, T. K., Pcolkins, A., Sivins, A., Lobovs, D., Ancans, G., Kreice, I., Budnikova, I., Jelovskis, I., Emhareb, A., Abaidalla, A., Hammed, A., Khairallah, M., Jibreel, S. S., Mohmmad, W. A. S., Hasan, W., Venskutonis, D., Daugela, E., Dainius, E., Juocas, J., Kutkevicius, J., Vaitkute, K., Bradulskis, S., Macas, A., Pauzas, H., Jokubauskas, M., Lizdenis, P., Budrikiene, R., Saladzinskas, Z., Dulskas, A., Volkoviene, G., Makauskiene, J., Kuliavas, J., Bernotaite, V., Danys, D., Kontrimaviciute, E., Poskus, E., Kryzauskas, M., Jakubauskas, M., Poskus, T., Jotautas, V., Zakaria, A. D., Kai, M. W. P., Zainy, R. H. M., Tan, S. S., Zain, W. Z. W., Zakaria, Z., Yusoff, Z. M., Raduan, F., Sagap, I., Razali, N. Y. F., Rahman, N. A., Kanthan, S. B. C., Nie, Y. C., Azman, Z. A. M., Ang, C. W., Tang, C. Y., Poh, K. S., Ng, K., Hashim, N. M., Xavier, R., Khong, T. L., Amir, A. S., Ali, C. S. C., Yew, C. K., Henry, F., Muniandy, J., Baharom, S., Eng, S. C. R., Hu, F. S. -M., Amin-Tai, H., Jabar, M. F., Satar, M. H. S. A., Fathi, N. Q., Rao, P. S., Podesta, A. M. C., Cini, C., Psaila, J., Debono, M., Sammut, M., Spiteri, N., Andrejevic, P., Muro, A. G., Leon, B. P., Perez, J. A. V., Quinonez, J. R. A., Vera, M. T. R., Gutierrez, V. M. M., Bobadilla, B. J., Martinez, C. M., De Leon Rendon, J. L., Hererro, J. A. V., Cuichan, M. V. Y., Baez, N. F., Prevost, P. G., Hoyos-Torres, A., Ruiz-Munoz, E. A., Alvarez-Bautista, F. E., Ortiz-Mendez, G., Zamudio-Bautista, J. L., Salgado-Nesme, N., Vergara-Fernandez, O., Sanchez-Valdivieso, E., Martinez, G., Navarrete-Aleman, J., Perez-Arellano, J., Maldonado-Barron, R., Hernandez-Krauss, R., Ousadden, A., Benjelloun, E. B., Bzikha, I., Ibnmajdoub, K., Mazaz, K., Marghich, O., Touzani, S., Benkabbou, A., Souadka, A., Ahmadi, B. E., Zaari, F., Laamri, I., Majbar, M. A., Mohsine, R., Van Berlo, C., Seuren, D., Gillissen, F., Aarts, F., Konsten, J., Van Heinsbergen, M., Schlooz, S., Naiqiso, A., Merrie, A., Varghese, C., Pugh, F., Bissett, I., Wilson, K., Mitchell, S., Dawson, C., Hill, C., Wright, D., Hubley, S., Lin, A., Jones, D., Siggins, L., Fagan, P., Wu, S., Ekwesianya, A., Nwoye, C., Agara, D., Ejiofor, G., Sundaynweke, N., Kwentoh, N., Ewah, R., Aremu, A., Ballah, A., Ningi, A., Ohia, E., Mienda, I., Aliyu, M., Oloko, N., Okunlola, A., Abiyere, H., Bolanle, O. E., Babatunde, O., Fatudimu, S., Orewole, T., Mba, E. L., Felix, M. S., Abdulfatah, M., Ibrahim, N., Masoro, U., Fakoya, A., Irabor, D., Anyadike, F., Ulasi, I., Orji, M., Afuwape, O., Ayandipo, O., Adeyeye, A., Aremu, I., Adegboye, K., Gbadegesin, P., Aminu, B., Aghadi, I. K., Makama, J. G., Joshua, S., Kache, S. A., Sheshe, A. A., Bala, A. M., Garzali, I. U., Abdullahi, M. M. M., Muhammad, N., Umar, N. A., Muhammad, S., Okoye, A., Emegoakor, C., Nwosu, C., Egwuonwu, O. 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(ORCID:0000-0002-2470-7858), Lorenzon L. (ORCID:0000-0001-6736-0383), Sollazzi L. (ORCID:0000-0002-2973-6236), Persiani R. (ORCID:0000-0002-1537-5097), Pezzuto R., Bengueddach, A., Tidjane, A., Tabeti, B., Behilil, C., Boudjenan-Serradj, N., Bensafir, S., Meharzi, S. E. I., Aissat, A., Ghouali, A. K., Larabi, K., Riffi, O., Kacimi, S. E. O., Mesli, S. N., Rezoug, W., Mitidieri, A., Jose, A., Pablo, C., Rodriguez, C. A., Panettiere, M. F., Barbalace, N., Juan, T., Lucena, J., Houdin, A., Fernandez, E., Lococo, J., Pedro, L., Loban, M., Vecchio, P., Grinblat, A., Carrie, A., Veracierto, F., Santillan, M., Napolitano, M., Avellaneda, N., Rosa, S. L., Gonzalez, C. M., Ferro, E., Munoz, J. P., Ventorutti, T., Cabrera, C., Carrizo, C., Mospane, C., Leiro, F., Espino, J., Trama, M., Bianchi, R., Potolicchio, A., Dindri, F., Buey, L., Lucas, N., Catalano, P., Astilleta, R., Quiroga, Y., Chwat, C., Valli, D., Alexandre, F., Martres, G., Rosato, G., Lemme, G., Romero, V., Doniquian, A. M., Pachajoa, D. A. P., Llahi, F., Fiorenza, J. M., Parodi, M., Ocana, N., Gallardo, A., Valenzuela, A., Perriello, J., Nador, R., Fermani, C., Garay, L., Blanco, P., Villalobos, S., Posner, F., Vieyra, N., Fiorito, P., Ciabattari, P., Kort, C. D., Daryanani, D., Smit, J., Gosselink, M. P., Janssen, N., Feiss, A., Lee, C. H. A., Taylor, D., Edington, J., Chen, N., Ong, W. M., Aigner, F., Moitzi, G., Gemes, G., Braumille, M., Mitteregger, M., Gerald, S., Uranitsch, S., Belarmino, A., Waha, J., Kahn, J., Treiber, M., Schemmer, P., Mikalauskas, S., Ibrahimli, A., Samadov, E., Orujova, E., Namazov, I., Alikhanli, J., Asgarov, M., Kutkut, A., Almahmeed, E., Aljawder, H., Juma, I., Johnston, K., Saeed, M. F., Khairi, S., Matovic, E., Omerasevic, M., Delibegovic, S., Hodzic, S., Rudell, A. G., Fuzari, J., Farah, J. F., Nadal, L. R. M., Dos Santos, M. B. A., Lupinacci, R. A., Pereira, T. S., Sete, A. D. S., Filho, A. L., De Souza Pires, B. L., Queiroz, F. L. D., Amaral, H. A. T., Dos Santos, M. A. M., De Miranda Silvestre, S. C., Hanan, B., Reis, C., Cassia, G., Luz, M. D., Delgado, M., Campanati, R., Silva, R., Bomfa-Barbosa, A., Alves, B. C., Costa, B. X. M., Cortes, B. G. W., Lemos, F. H. T., Arreguy-Borges, K., Silva, T. B., Assis, A., Freitas, A. H., Rezende, D., Silva, H., Alvarenga, I., Cascais, R., Silva, T., Santos, G., Pinto, H., Silva, I., Leite, L., Massahud, M., Meyer, M., Tiburcio, R., Martinez, C. A. R., Espinha, D. R., Marson, F. A. L., De Oliveira Goes, I. A., De Souza Artioli, L. M., Boschiero, M. N., Takahashi, C. Y., Oliveira, F. G. D., Lyra, H. F., De Oliveira, J. C. C., Santos, J. M. D., Gerber, M. T., Erdmann, T. R., Barbosa, A., Fernandes, A., Junior, A. N., Junior, H. M., Moreira, J., Ribeiro, M., Moreira, P., Carvalho, A., Santos, B., Fidelis, F., Cruz, I., Codes, L., Aibe, R., Boudoux, S., Favacho, B. C., Pinto, F., Gava, G., Pivati, I. R., Vilain, L. F., Kim, N., Nunes, R. L., Dimitrov, D., Peneva, K., Karamanliev, M., Dimitrova, S., Ivanov, T., Atanasov, B., Dzharov, G., Shtereva, M., Slavchev, M., Belev, N., Krastev, P., Arabadzhiev, A., Tonova, D., Tzoneva, D., Sokolov, M., Gribnev, P., Maslyankov, S., Pavlov, V., Bakmaz, B., Dijan, E., Coza, I., Mihanovic, J., Kucic, J., Sulen, N., Katusic, Z., Hudacek, K., Farkasova, M., Markova, M., Grolich, T., Kala, Z., Pazdirek, F., Hoch, J., Filipova, L., Kocian, P., Prikryl, P., Hogn, A., Moller, B., Slot, D. K., Baelum, J. K., Cour, K. L., Ellebaek, M. B., Eriksen, N. D., Mahmoud, A., Abdellatif, A., Nafea, A., Ewedah, M., Soliman, M., Yakout, N., Argawy, O., Sallam, I., Kamel, I., Sherif, M., Ashmawy, S., Ali, A., Saad, M., Ahmed, M., Mohamed, M., Mohamed, N., Mahmoud, S., Rashed, A. M., Abd-Errazik, M. A., Ammar, M. A., Mohammed, R., Ebrahem, A., Aal, A. A. E., Abdou, K., Wagdy, M., Qassem, M., Taha, M., El-Wafa, Y. A., Shehta, A., Metwally, A. E., Hamed, H., Ali, M. A., Elrefai, M., Sorogy, M. E., Abdelkhalek, M., Ragab, A., Refky, B., Metwally, I. H., Kamal, M., Zuhdy, M., Shetiwy, M., Sakr, A., Elfallal, A., Elfeki, H., Eldakroury, I., Elbahrawy, K., Mostafa, M., Emile, S., Tessema, A., Tasew, A., Gezahegn, H., Bekele, K., Belay, M., Gudisa, Z., Teferu, Z., Vayrynen, A., Kechagias, A., Turunen, A., Katunin, J., Parhiala, M., Pengerma, P., Lahti, P., Carpelan, A., Vihervaara, H., Huhtinen, H., Pasonen, J., Heino, R., Pakarinen, S., Falenius, V., Pinard, B., Nobile, C., Duchalais, E., Drissi, F., Meurette, G., Podevin, J., Lepenndu, M., Hoetzel, A., Jud, A., Jauch, D., Stefan, F. -F., Neeff, H., Holzner, P., Nguyen, P., Ryl, A., Kehl, F., Pullig, F., Baral, J., Munch, S., Futterer, C., Reissfelder, C., Sandra-Petrescu, F., Herrle, F., Hardt, J., Lamm, L., Seyfried, S., Gharbi, A., Aydin, F., Stavrou, G., Sperber, J., Deken, J. 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H., Bains, L., Kumar, M., Singh, N., Lal, P., Sharma, A., Kumar, A., Garg, L., Aggarwal, M., Jakhar, R., Bose, B., Huda, F., Thakur, N., Dhar, P., Seenivasagam, K., Prakash, S., Chaudhari, A., Shukla, A., Mahakalkar, C., Saxena, G., Mahuli, K., Kaple, M., Kshirsagar, S., Mehraj, A., Parray, F., Aziz, G., Chowdri, N., Wani, R. F., Gurcoo, S., Shah, Z., Polamreddy, B. M., Madhavan, S., Subbarayan, S., Vino, S., Aravindan, U., George, G., Harikumar, C. K., Yadev, I. P., Chisthi, M., Revathy, P. S., Sreekumar, R. C., Vijayan, V., Theodore, B., Victor, C., Jesudason, M. R., Arulappan, N., Philip, R., Mittal, R., Durai, S., Creavin, B., Cullinane, C., Davis, C., Flynn, C., Liam, D., Cooke, F., Earley, H., Mccullough, P., Neary, P., Hamilton, V., Trani, A. D., Conversano, I., Cianci, P., Petta, R., Picciariello, A., Altomare, D. F., Martines, G., Grasso, S., Moffa, S., Papagni, V., Zanoni, A., Belvedere, A., Romano, A., Croce, G. D., Tanzanu, M., Rottoli, M., Cardelli, S., Lauro, A., Sartarelli, L., Binetti, M., Cervellera, M., Tonini, V., Sanna, B., Pusceddu, E., Runfola, M., Manunza, R., Pisanu, A., Cois, A., Frongia, F., Esposito, G., Podda, M., Mura, P., Cutelle, C., Ammerata, G., Sena, G., Pignataro, M., Scozzafava, M., Mazza, M., Bruni, A., Curro, G., Hila, J., Ammendola, M., Curcio, S., Signorelli, V., Marano, A., Sasia, D., Borghi, F., Giuffrida, M. C., Bonardello, M., Palmisano, S., Testa, V., Porta, A., Scaltrini, F., Iacob, G., Gaspa, I., Guatteri, L., Coladonato, M., Zapparoli, A., Pesce, A., Feo, C. V., Pindozzi, F., Bigoni, I., Torchiaro, M., Fabbri, N., Cianchi, F., Staderini, F., Elena, F., Coratti, F., Barbato, G., Fortuna, L., Romagnoli, S., Bergamini, C., Villa, G., Cecchini, I., Martellucci, J., Izzo, M., Trafeli, M., Scheiterle, M., Manoocheehri, F., Cagnazzo, F., Spampinato, M. 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A., Mohsine, R., Van Berlo, C., Seuren, D., Gillissen, F., Aarts, F., Konsten, J., Van Heinsbergen, M., Schlooz, S., Naiqiso, A., Merrie, A., Varghese, C., Pugh, F., Bissett, I., Wilson, K., Mitchell, S., Dawson, C., Hill, C., Wright, D., Hubley, S., Lin, A., Jones, D., Siggins, L., Fagan, P., Wu, S., Ekwesianya, A., Nwoye, C., Agara, D., Ejiofor, G., Sundaynweke, N., Kwentoh, N., Ewah, R., Aremu, A., Ballah, A., Ningi, A., Ohia, E., Mienda, I., Aliyu, M., Oloko, N., Okunlola, A., Abiyere, H., Bolanle, O. E., Babatunde, O., Fatudimu, S., Orewole, T., Mba, E. L., Felix, M. S., Abdulfatah, M., Ibrahim, N., Masoro, U., Fakoya, A., Irabor, D., Anyadike, F., Ulasi, I., Orji, M., Afuwape, O., Ayandipo, O., Adeyeye, A., Aremu, I., Adegboye, K., Gbadegesin, P., Aminu, B., Aghadi, I. K., Makama, J. G., Joshua, S., Kache, S. A., Sheshe, A. A., Bala, A. M., Garzali, I. U., Abdullahi, M. M. M., Muhammad, N., Umar, N. A., Muhammad, S., Okoye, A., Emegoakor, C., Nwosu, C., Egwuonwu, O. A., Ekwunife, O., Amadigwe, R., Ojiakor, S., Akere, A., Okereke, C., Olaleye, O., Ige, O., Olubayo, O., Olatiilu, T., Idris, M., Shehu, A., Oluyori, D., Nwabuoku, E., Ukwubile, L., Bashir, M., Daniyan, M., Rauf, H., Ali, M., Zakaria, M., Hameed, M., Amanullah, N., Chawla, T., Waqar, U., Jamal, A., Butt, A., Kerawala, A., Samson, S., Dodhy, A. A., Gill, A. J., Malik, A., Ali, D., Mohsin, H., Afzal, M. F., Batool, S., Suleman, A., Khalid, J., Zafar, M., Dilawar, M., Janjua, M. H., Sarwar, M. Z., Naqi, S. A., Akbar, A., Afzal, A., Anwar, J., Gondal, K. M., Shaukat, M., Waheed, M., Sohail, M., Mukhtiar, N., Ammar, A. S., Hussain, A., Khan, A. N., Sarwar, A., Khan, I., Khattak, S., Oqaili, B., Saada, B., Zatari, D., Jubran, F., Hamdan, F., Emar, M., Alawi, R., Jacome, G., Insturain, I., Arauz, J., Hurtado, M., Beron, R. I., Castano, R., Cao, V. H. B., Kwiatkowski, A., Dobkowski, G., Bartosiak, K., Waledziak, M., Mozanski, M., Zadrozna, M., Kowalewski, P., Fiedziuk, A., Watroba, A., Los, A., Sitarska, M., Rzaca, M., Zawadzki, M., Czarnecki, R., Tavares, C., Santos, F., Borges, F., Real, J. C., Lima, M. J., Carlos, S., Pereira, V., Pacheco, A., Gomes, G., Pimenta, J., Elisiario, L., Jervis, M., Goncalves, V., Pedro, V., Jordao, D., Neves, F. R., Conceicao, L., Angelo, M. D., Marques, P., Saraiva, R. P., Caroco, T. V., Windels, A., Machado, A., Ribeiro, C., Velez, C., Oliveira, J., Melo, M. R., Lima, R., Pires, A., Lareiro, C., Martins, R., Revez, T., Martins, A., Cardoso, D., Alegre, I., Estevao, P., Andrade, D., Gomes, D. C., Duarte, M. J., Custodio, P., Nemesio, R. A., Rodrigues, S., Correia, A., Domingos, H., Herrando, I., Azevedo, J., Fernandez, L., Azevedo, P., Vieira, P., Torre, A., Amado, A., Paiva, M., Saraiva, R., Costa, S., Mendes, T., Queiros, T., Silva, A., Faustino, A., Freitas, A., Mendes, J., Amaral, L., Quintanilha, R., Coelho, A. M., Ribeiro, A., Pinto, C., Ribeiro, N., Reis, R., Fernandes, V., Sanches, A., Amorim, E., Miguel, I., Rachadell, J., Sanches, M., Oliveira, S., Baptista, V., Roxo, A., Devesa, H., Teslyak, O., Barradas, R., Marques, S., Martins, S., Pepino, S., Deus, A. C., Ferreira, A., Marinho, D., Sousa, D., Martins, M. J., Matias, N., Pinto, A., Correia, D., Amado, F., Cordeiro, L., Morales, M., Lamas, M., Marcal, S., Rodrigues, A. I., Santos, A., Marcal, A., Oliveira, A., Gomes, C., Ferreira, C., Marques, R., Chitul, A., Alexandrescu, C., Bezede, C., Cristian, D., Mandi, D., Grama, F., Ungureanu, R., Stoica, B., Diaconescu, C., Ciubotaru, C., Tanase, I., Grintescu, I., Negoi, I., Negoita, V. M., Calin, C., Simeanu, C., Ciotarla, D. C., Caltea, M., Mirica, R. M., Luca, A., Pasca, A., Vlad, C., Bonci, E. -A., Stefanescu, I., Achimas-Cadariu, P. A., Gata, V. A., Capusan, A., Petrisor, C., Dindelegan, G., Seicean, R., Scurtu, R., Bintintan, V., Fagarasan, V., Ionescu, C., Crisan, D., Zanc, L., Ene-Cocis, M. -V., Muresan, M. -S., Mihalcea, S. M., Dudric, V., Musina, A. -M., Ristescu, A. -I., Roata, C. -E., Moglan, M., Dimofte, M. -G., Lunca, S., Iacob, S., Dychko, A., Litvin, A., Kapustina, A., Provozina, A., Anokhin, E., Zabiyaka, M., Shin, A., Djumabayev, K., Kuznetsova, M., Gordeyev, S., Kochkina, S., Mamedli, Z., Markaryan, D., Galliamov, E., Semina, E., Agapov, M., Malahov, P., Garmanova, T., Kakotkin, V., Zaycev, A., Sumbaev, A., Bedzhanyan, A., Orman, E., Petrenko, K., Bredikhin, M., Frolova, Y., Tulina, I., Bashilkina, O., Tsarkov, P., Rodimov, S., Stamov, V., Balaban, V., Alexnder, A., Yanishev, A., Rogozhev, D., Yakunina, N., Chubukova, N., Nugmanov, R., Karachun, A., Petrov, A., Domanskiy, A., Panaiotti, L., Smolina, M., Sapronova, T., Pelipas, Y., Zagaynov, E., Khrykov, G., Davidovskaja, L., Burlov, N., Mankevich, N., Tverdohlebova, T., Bogatikov, A., Lodygin, A. V., Krasnoselsky, C., Vasiukova, E. -S., Kopteyev, N. R., Ovchinnikov, T., Kashchenko, V. A., Novikova, A., Terentyeva, E., Kuleshov, O., Pavlov, R., Koshel, A., Kostromitsky, D., Drozdov, E., Klokov, S., Camacho, A., Khan, F. N., Bandar, M. A., Shamim, R., Chowdhury, S., Kovacevic, B., Krdzic, I., Zdravkovic, M., Kenic, M., Milentijevic, M., Petkovic, N., Radulovic, R., Ngu, J., Teo, N. Z., Singh, P. A., Ong, S. Y., Li, S., Siew, B., Chee, C., Koh, J. J. M., Lee, K. Y., Tan, K. K., Wong, S. C., Loh, W., Pujol, A. F., Rubio, J. C., Farres, L. P., Vendrell, L. L., Del Olmo, M. I. U., Pedregosa, A. B., Galmes, C., Luckute, D., Casanova, D., Artigot, M., Guedes, X., Olivella, Y., Sarda, M. S., Toscano, M. J., Damieta, M. P., Pera, M., Goncalvez, S. A., Galvez, S. T., Ruiz, S. S., Basany, E., Marinello, F., Villarino-Villa, L., Heras, M. V. -L., Martin-Sanchez, R., Mata, R. M., Blanco-Colino, R., Otero, A., Lacy, A. M. D., Sanahuja, J. M., Bravo, R., Ferraz, T., Gonzabay, V., Gonzalez, F., Menendez, P., Del Castillo, V. C. G., Lopez-Pelaez, V. M., Silva, A. S., Lillo-Garcia, C., Tauler, E. M., Sanchez-Guillen, L., Manresa, M. C. E., Perez, S. L., Llopis, S. Q., Rubio, A. V., Castillo, E. R., Miramon, F. J. J., Rodriguez, J. L. R., Rizo-Lamberti, L. A., Garrido, P. G., Carneros, V. J., Alfonso, B. A., Sierra, B. G., Amador, C. G., Gomendio, M. D. P., Palomino, M. V. R., De La Plaza Llamas, R., Cafranga, E. G., Ramos, J. L. E., Estudillo, M. C., Perez, R. E., Pernas, R. M., Fernandez, S. D. L., Bautista, W. M. S., Llamazares, A. L., Valbuena, A. L., Moran, L. A., Alvarez, L. J., Raposo, L. G., Ceron, S. F., Gonzalez, T. E., Calvo, A. C., Valcarcel, C. R., Pena, J. P., Gomez, L. M. J., Diez, M. C., Lindenbaum, P. D., Mata, S. K., Ruiz-De-La-Hermosa, A., Abad-Motos, A., Toribio-Combarro, B., Ripolles-Melchor, J., Fuenmayor-Valera, M. L., Ortega-Domene, P., Loscos, A., Pueblo, C. S. D., Dziakova, J., Muguerza, J. M., Carlin, P. S., Anula, R., Mouvet, Y., Forero-Torres, A., Andres, B. D. S., Marcos, C. M., Rubio, I., Pascual, I., Yague, J., Alcolea, N. G., Alonso, A., Dieguez, B., Ibanez, I., Perez, J. L., Losada, M., Garcia-Conde, M. G., Hernandez, M., Blazquez-Martin, A., Vera-Mansilla, C., Mendoza-Moreno, F., Hernandez-Salvan, J., Diez-Alonso, M., Hernandez-Juara, P., Barrena-Blazquez, S., Minaya-Bravo, A. M., Galvan-Perez, A., Miguel-Mendez, C. S., Gonzalez-Gonzalez, E., Alvarez-Diez, M., Garcia-Urena, M. A., Llorente-Moreno, M., Ruiz-Lozano, C., Colas-Ruiz, E., Perez-Calvo, J., Gomila-Sanso, J. A., Alvarez-Llano, L., Serrano-Fuentes, S. C., Soto-Montesinos, C., Dedeu-Bastardas, I., Perez-Reche, I., Labro-Ciurans, M., Pardo-Lopez, S., Perez, E. G., Fernandez, I. O., Canals, L. O., Espino, P. C., Ruano, P. G., Ricardo, V., Ros, E. P., Manuel, E. M., Buleje, J. A. B., Prats, M. M. C., Banos, P. A. P., Gonzalez, P. M., Celdran, R. G., Pellicer-Franco, E. M., Valero-Navarro, G., Vicente-Villena, J. P., Martinez-Mercader, M. M., Baeza-Murcia, M., Mengual-Ballester, M., Soria-Aledo, V., Fernandez-Martinez, D., Varela-Rodriguez, L., Garcia-Florez, L. J., Fernandez-Hevia, M., Gonzalez-Diaz, M. J., Fernandez-Arias, S., Puertas, C. P., De San Pio Carvajal, E., Cebolla, E. S., Brainsa, E., Bayo, J. M. M., Castro, M. C., Blanco, R. R., Gutierrez, E., Pinto, F. L., Alegre, J. M., Flores, N., Osullivan, S. N., Fernandez, B. F., Alonso, J. E., Conde, J. G. A., Ropero, N. M., Bayon, R. A., Dominguez, S. H., Ramirez, S., Pablos, A. M. D., Perez-Sanchez, A., Cano-Matias, A., Del-Rio-Lafuente, F. -J., Caballero-Delgado, J., Hernandez, J. V., Gomez-Rosado, J. -C., Martinez, C., Cholewa, H., Sancho-Muriel, J., Alberola, M. J., Navasquillo, M., Primo, V., Moreno, V., Espi-Macias, A., Moro-Valdezate, D., Carrascosa-Morales, I., Martin-Arevalo, J., Soro-Domingo, M., Garcia-Botello, S., Pla-Marti, V., Abellan, A. M., Perez, C. M., Cortes, G. F. V., Blasco, L. F., Chornet, M. R., Martin, R. S., Diego, A. R. -D., Vazquez-Fernandez, A., Pascual, A., Andres-Asenjo, B. D., Heredia, J. B. D., Ruiz-Soriano, M., Rodriguez-Jimenez, R., Iribarren, E. M., Rodriguez, E. V. F., Garcia, M. D. C. C., Garcia-Senorans, M. P., Valderrama, O. C., Rodriguez, P. F., Santos, R. S., Curras, R. P., Vigorita, V., Roche, C. G., Delgado, E., Lafuente, F., Gascon, I., Mallen, M. V. D., Saudi, S., Fraj, V., Wickramasinghe, D., Zoysa, I. D., Samarasekera, N., Wickramarathne, R., Dassanayake, V., Balathayalan, Y., De Silva, D., Perera, M., Pulleperuma, S., Jayasekara, S., Wijenayake, W., Gunetilleke, B., Abeysinghe, N., Chandrasinghe, P., Kumarage, S., Abdalradiy, A. G., Widatalla, A. B. H., Ahmed, A. Y., Mohamed, H. A., Hamid, H. K. S., Ali, M. H., Eldin, S. J., Agger, E., Jutesten, H., Lindgren, J., Lepsenyi, M., Azhar, N., Buchwald, P., Hansdotter, P., Ekepil, A., Linden, A., Brandstrom, G., Smedberg, J., Schiffer, E., Ris, F., Longchamp, G., Meyer, J., Dupret, L., Buchs, N., Galetti, K., Regusci, L., Grischott, M., Malugani, M., Mouhandes, A. E. -F., Danial, A. K., Khayat, M., Sbahi, M. H. E., Marawy, M. K., Abdullah, M. A., Douba, Z., Mansour, A., Niazi, A., Hamza, A., Mohamad, A. H., Awead, M., Mohammad, S., Salloum, S., Jabar, A. A., Zazo, A., Shebli, B., Ayoub, K., Younes, L., Bannoud, M. H., Zazo, R., Saad, A., Hamdan, A., Wakkaf, H., Adra, L., Souliman, M., Anton, M., Hannouf, S., Wang, J. Y., Li, K. L., Cheng, K. I., Ji, S. J., Hsieh, Y. C., Parlak, E. A., Demir, M., Kara, U., Peker, Y. S., Yigit, D., Unal, N., Iflazoglu, N., Yalkin, O., Topal, S., Gulcu, B., Ozturk, E., Gumbelek, G., Terkanlioglu, S., Koklucan, A., Ince, G., Sen, M., Isik, O., Kural, S., Akesen, S., Yilmazlar, T., Sungurtekin, H., Sungurtekin, U., Vural, U., Ozgen, U., Isik, A., Onk, D., Kurnaz, E., Ozker, T. S., Ipek, A., Ferlengez, A., Erturk, C., Tatar, C., Sevik, H., Akay, O., Sensoy, O., Hayirlioglu, M. B., Aktas, S., Ozben, V., Aliyeva, Z., Mutlu, A. U., Gokay, B. V., Saracoglu, C., Aytac, E., Gulmez, M., Isik, M. U., Hacim, A., Akbas, A., Soyhan, F., Turgut, M. A., Demirgan, S., Meric, S., Altinel, Y., Baris, B., Akova, E., Kahraman, E., Kucuk, H. F., Saracoglu, K. T., Kaya, S., Lel, S., Gurbulak, E. K., Caz, E., Kostek, M., Mihmanli, M., Yazici, P., Oba, S., Kirkan, E. F., Ulgur, H. S., Kalin, M., Dinkci, M. D., Ozkan, O. F., Duzgun, O., Ozturk, S., Zengin, A. K., Askar, A., Sanli, A. N., Erginoz, E., Ozcelik, M. F., Ergun, S., Uludag, S. S., Kara, D., Yilmaz, G., Sarici, I. S., Kara, Y., Incesu, A., Arican, C., Atici, S. D., Kaya, T., Gezer, T., Kirmizi, Y., Kamer, E., Aydin, G., Namdaroglu, O., Adakaya, S., Canda, A. E., Ozzeybek, D., Coskun, N., Sokmen, S., Ozkardesler, S., Bisgin, T., Miftari, A., Caliskan, C., Akgun, E., Avseren, G., Deniz, N., Bozbiyik, O., Yoldas, T., Guresin, A., Zayakov, G., Posteki, G., Utkan, N. Z., Tatar, O. C., Akcay, O., Guler, S. A., Mantoglu, B., Demirel, E., Akin, E., Gonullu, E., Altintoprak, F., Palabiyik, O., Bayhan, Z., Ciftci, A. B., Colak, E., Aybar, E., Celik, H. K., Eraslan, H., Yemez, K., Ozbilgin, S. S., Senol, S., Gultekin, F. A., Piskin, O., Guler, O., Karadere, Y., Kakeeto, A., Oguttu, B., Sikakulya, F. K., Lule, H., Rybachuk, A., Shudrak, A., Beznosenko, A., Lisnyy, I., Rozhkova, V., Zvirych, V., Alawlaqi, D., Jamali, F. E., Balooshi, I. A., Albers, M., Ali, N. A., Church, R., Dudas, G., Wells, J., Pavlova, M., Sebastiani, S., Paterson, C., Kaushal, M., Patel, P., Panchal, S., Handa, S., Tezas, S., Zaidi, S. -N., Raj, G., Wright, J., Hallam, S., Karandikar, S., Gates, Z., Marshall, A., Thompson, A., Tennakoon, A., Rao, M., Callan, R., Tufail, S., Rajendran, G., Polisetty, K., Husain, N., Clarke, N., Naranayanasamy, S., Hallett, A., Lorejo, E., Ward, N., Antakia, R., Xanthis, A., Simillis, C., Tweedle, E., Panagiotopoulou, I., Grimes, L., Mounstephen, L., Bocancia, R., Carden, C., Lynch, J., Noveros, M. S., Shaalan, R., Khalil, T., Marshall, W., Hodge, K., Balfour, J., Mcintosh, K., Buijs, L., Potter, M. A., Yule, M., Vaughan-Shaw, P. G., Smith, S., Anderson, T., Mcdermott, F. D., Daniels, I. R., Tapp, J., Smart, N., Rajaretnam, N., Bethune, R., Clark, T., Delimpalta, C., Liao, C., Banham, G., Induruwage, L., Velchuru, V., Lawrence, A., Rahman, A., Bennett, J., Badawi, M., Harshen, R., Bhargava, A., Gorrela, K., Jumah, M., Venn, M., Hanson, M., Arya, S., Atendido, T., Shrestha, A., Cook, E., Rakhimov, I., Collins, J., Alamin, N., Vigneswaran, N., Basnyat, P., Shamardal, A., Chacko, A., Wanshantha, D., Bisheet, G., Ebdewi, H., Abdellatif, M., Adu-Poku, P., Tore, A., Adams, F., Allen, K., Ahmed, K., Kulkarni, N., Chitnis, A., Patel, H., Magsino, J., Sarodaya, V., Minicozzi, A., Dempsy, C., Ahmed, H., Jayasinghe, J. D., Okail, M. H., Thaha, M., Hallworth, S., Parmar, C., Chua, L., Pizanias, M., Samin, R., Young, T., Sagar, J., Yorkmui, L., Cirocchi, N., Ahmed, S., Barreda, S. C., Kudchadkar, S., Baker, A., Jayasankar, B., Balasubramaniam, D., Jackson, J., Abdelsaid, K., Hassan, M., Shetty, S., Coldwell, C., Davies, E., Nader, H., Raistrick, M., Ryska, O., Hawkin, P., Raymond, T., Witjes, C., Steen, K. V. D., Crabtree, N., Boyce, S., Somera, W., Woodward, A., Ryan, K., Kassai, M., Aleem, M., Ghosh, A., Rixson, D., Lewis, E., Lynch, N., Shovelton, C., Zywicka, E., Guest, F., Barton, J., Purnell, R., Bamford, R., Teare, T., Adams, B., Chmielewski, G., Smith, I., Smith, L., Connolly, L., Niblett, R., Singh, A., Halliwell, G., Paraoan, M., Doree, N., Asaad, P., Kilbride, C., Carpenter, H., Wilson, J., Fletcher, J., Vijayagopal, K. A., Abbakar, M., Zaimis, T., Walsh, A., Kubisz-Pudelko, A. A., Nono, J., Pippard, L., Chowdhary, M., Dalton, R., Moussa, T., Dominguez, F., Solla, G., Curbelo, J., Laurini, M., Viola, M., Brito, N., Al-Alnsi, A., Al-Naggar, H., Saryah, L., Al-Shehari, M., Alsayadi, R., Al-Hutheifi, R., Shream, S., Biondi A. (ORCID:0000-0002-2470-7858), Lorenzon L. (ORCID:0000-0001-6736-0383), Sollazzi L. (ORCID:0000-0002-2973-6236), Persiani R. (ORCID:0000-0002-1537-5097), and Pezzuto R.

Abstract

Background: Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.Methods: The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.Results: A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31

Published
2024

18. A systematic comparison of supervised classifiers

Author

Amancio, D. R., Comin, C. H., Casanova, D., Travieso, G., Bruno, O. M., Rodrigues, F. A., and Costa, L. da F.

Subjects
Computer Science - Learning
Abstract

Pattern recognition techniques have been employed in a myriad of industrial, medical, commercial and academic applications. To tackle such a diversity of data, many techniques have been devised. However, despite the long tradition of pattern recognition research, there is no technique that yields the best classification in all scenarios. Therefore, the consideration of as many as possible techniques presents itself as an fundamental practice in applications aiming at high accuracy. Typical works comparing methods either emphasize the performance of a given algorithm in validation tests or systematically compare various algorithms, assuming that the practical use of these methods is done by experts. In many occasions, however, researchers have to deal with their practical classification tasks without an in-depth knowledge about the underlying mechanisms behind parameters. Actually, the adequate choice of classifiers and parameters alike in such practical circumstances constitutes a long-standing problem and is the subject of the current paper. We carried out a study on the performance of nine well-known classifiers implemented by the Weka framework and compared the dependence of the accuracy with their configuration parameter configurations. The analysis of performance with default parameters revealed that the k-nearest neighbors method exceeds by a large margin the other methods when high dimensional datasets are considered. When other configuration of parameters were allowed, we found that it is possible to improve the quality of SVM in more than 20% even if parameters are set randomly. Taken together, the investigation conducted in this paper suggests that, apart from the SVM implementation, Weka's default configuration of parameters provides an performance close the one achieved with the optimal configuration.

Published
2013
Full Text
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21. Advances in molecular quantum chemistry contained in the Q-Chem 4 program package

Author

Shao, Y, Gan, Z, Epifanovsky, E, Gilbert, ATB, Wormit, M, Kussmann, J, Lange, AW, Behn, A, Deng, J, Feng, X, Ghosh, D, Goldey, M, Horn, PR, Jacobson, LD, Kaliman, I, Khaliullin, RZ, Kus̈, T, Landau, A, Liu, J, Proynov, EI, Rhee, YM, Richard, RM, Rohrdanz, MA, Steele, RP, Sundstrom, EJ, Woodcock, HL, Zimmerman, PM, Zuev, D, Albrecht, B, Alguire, E, Austin, B, Beran, GJO, Bernard, YA, Berquist, E, Brandhorst, K, Bravaya, KB, Brown, ST, Casanova, D, Chang, CM, Chen, Y, Chien, SH, Closser, KD, Crittenden, DL, Diedenhofen, M, Distasio, RA, Do, H, Dutoi, AD, Edgar, RG, Fatehi, S, Fusti-Molnar, L, Ghysels, A, Golubeva-Zadorozhnaya, A, Gomes, J, Hanson-Heine, MWD, Harbach, PHP, Hauser, AW, Hohenstein, EG, Holden, ZC, Jagau, TC, Ji, H, Kaduk, B, Khistyaev, K, Kim, J, King, RA, Klunzinger, P, Kosenkov, D, Kowalczyk, T, Krauter, CM, Lao, KU, Laurent, AD, Lawler, KV, Levchenko, SV, Lin, CY, Liu, F, Livshits, E, Lochan, RC, Luenser, A, Manohar, P, Manzer, SF, Mao, SP, Mardirossian, N, Marenich, AV, Maurer, SA, Mayhall, NJ, Neuscamman, E, Oana, CM, Olivares-Amaya, R, Oneill, DP, Parkhill, JA, Perrine, TM, Peverati, R, Prociuk, A, Rehn, DR, Rosta, E, Russ, NJ, Sharada, SM, Sharma, S, Small, DW, and Sodt, A

Subjects
quantum chemistry, electron correlation, electronic structure theory, Q-Chem, computational modelling, software, density functional theory, Chemical Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Physical Chemistry, Theoretical and Computational Chemistry, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Physical Chemistry (incl. Structural)
Abstract

A summary of the technical advances that are incorporated in the fourth major release of the Q-Chem quantum chemistry program is provided, covering approximately the last seven years. These include developments in density functional theory methods and algorithms, nuclear magnetic resonance (NMR) property evaluation, coupled cluster and perturbation theories, methods for electronically excited and open-shell species, tools for treating extended environments, algorithms for walking on potential surfaces, analysis tools, energy and electron transfer modelling, parallel computing capabilities, and graphical user interfaces. In addition, a selection of example case studies that illustrate these capabilities is given. These include extensive benchmarks of the comparative accuracy of modern density functionals for bonded and non-bonded interactions, tests of attenuated second order Møller-Plesset (MP2) methods for intermolecular interactions, a variety of parallel performance benchmarks, and tests of the accuracy of implicit solvation models. Some specific chemical examples include calculations on the strongly correlated Cr2 dimer, exploring zeolite-catalysed ethane dehydrogenation, energy decomposition analysis of a charged ter-molecular complex arising from glycerol photoionisation, and natural transition orbitals for a Frenkel exciton state in a nine-unit model of a self-assembling nanotube.

Published
2015

29. On minimum time vehicle manoeuvring : the theoretical optimal lap

Author

Casanova, D. and Sharp, Robin S.

Subjects
629.049
Abstract

This work is a research on the minimum time vehicle manoeuvring problem, with a particular application to finding the minimum lap time for a Formula One racing car. The proposed method allows to solve the general problem of evaluating the vehicle lateral and longitudinal controls which yield the minimum time required to traverse a lap of a circuit. The minimum time vehicle manoeuvring problem is formulated as one of Optimal Control and is solved using mathematical programming methods. Novel techniques are employed to solve the resulting non-linear programming problem which allow to achieve effective optimisation with satisfactory accuracy, robustness and computational efficiency. Particularly, the proposed solution strategy is generally applicable to any arbitrarily complex vehicle mathematical model. Car and circuit models are set up, and the optimisation program is applied to investigate the sensitivity of the vehicle performance with respect to vehicle design parameters, such as the yaw moment of inertia, the total mass and the weight distribution. Furthermore, the minimum time manoeuvring problem is solved for very different vehicle configurations. The optimisation program accurately quantifies the vehicle performance in terms of manoeuvre time, and the nature of the optimal solution is shown to be always in excellent agreement with the dynamic properties of the vehicle model. A part of the work is devoted to the development of a strategy to obtain an initial estimate of the racing line and of the vehicle lateral and longitudinal controls to be used at the start of the optimisation. Two algorithms to compute the racing line using on board measured data from the real car are presented. A new mathematical model for the vehicle steering control is derived. The model uses multiple preview information of the intended path. Its structure derives from linear optimal preview control theory, but it is adapted to deal with non-linear vehicle operations arising from the inevitable tyre force saturation in vigorous manoeuvring. The excellent path following capability of the model is demonstrated by solving various path following tasks involving moderate manoeuvring and racing speeds.

Published
2000

40. Digital platform to assess risk to natural hazards in Mexico city, Mexico

Author

Novelo Casanova, D. and Suarez, G.

Abstract

To build disaster resilience, the National Autonomous University of Mexico and the Mexico City’s Secretariat of Education, Science, Technology, and Innovation, supported a project to develop a digital platform to assess risk to natural hazards in Mexico City. This platform is based on a Geographical Information System (GIS) and its main purpose is to identify the associated risk to the following natural hazards: earthquakes, volcanic eruptions, floods, mass movement processes, forest fires, and land subsidence. Besides characterizing the local hazards for different return periods, social vulnerability was determined using thirteen indicators from data of the 2010 Mexican Census of Population and Housing. We recognize social vulnerability as those social conditions that make a community susceptible to be damaged by a hazard and it is an inherent characteristic of society. Population and critical facilities (hospitals, schools, telecommunications, etc.) were considered as exposed elements. “Social risk” is expressed using a qualitative spatial multi-criteria evaluation technique by superimposing the calculated GIS’s raster of the social vulnerability over individual hazard rasters. The resulting values measure the “likelihood of risk”. Both, vulnerability and hazard, were classified into five categories with values from 1 to 5, where 1 is low and 5 very high. As a result, we obtain a meshing array that reflects the likelihood of social risk for specific hazards. The main purpose of this tool is to provide local authorities elements for land use regulations and urban development by strengthening their prevention and mitigation actions., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

Published
2023
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41. Is Unicentric Familial Papillary Thyroid Microcarcinoma Different from Multicentric?

Author

Ríos, Antonio, primary, Ruiz-Pardo, J, additional, Román, Andrés Balaguer, additional, Puñal, JA, additional, Moreno, P, additional, Mercader, E, additional, Ferrero, E, additional, Morlán, MA, additional, Martín, J, additional, Durán, M, additional, Bravo, JM, additional, Casanova, D, additional, Salvador-Egea, MP, additional, Torregrosa, NM, additional, Exposito-Rodríguez, A, additional, Martínez-Fernández, G, additional, Carrión, AM, additional, Vidal, O, additional, Herrera, F, additional, Ruiz-Merino, G, additional, and Rodríguez, JM, additional

Published
2023
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47. First world consensus conference on pancreas transplantation: Part I—Methods and results of literature search

Author

Boggi, U, Vistoli, F, Marchetti, P, Kandaswamy, R, Berney, T, Andres, A, Arbogast, H, Badet, L, Baronti, W, Bartlett, S, Benedetti, E, Branchereau, J, Burke, G, Buron, F, Caldara, R, Cardillo, M, Casanova, D, Cipriani, F, Cooper, M, Cupisti, A, de Koning, E, Davide, J, Drachenberg, C, Ettorre, G, Fernandez Cruz, L, Fridell, J, Friend, P, Furian, L, Gaber, O, Gruessner, A, Gruessner, R, Gunton, J, Han, D, Iacopi, S, Kauffmann, E, Kaufman, D, Kenmochi, T, Khambalia, H, Lai, Q, Langer, R, Maffi, P, Marselli, L, Menichetti, F, Miccoli, M, Mittal, S, Morelon, E, Napoli, N, Neri, F, Oberholzer, J, Odorico, J, Ollinger, R, Oniscu, G, Orlando, G, Ortenzi, M, Perosa, M, Perrone, V, Redfield, R, Ricci, C, Rigotti, P, Robertson, R, Ross, L, Rossi, M, Saudek, F, Scalea, J, Schenker, P, Secchi, A, Socci, C, Sousa Silva, D, Squifflet, J, Stock, P, Stratta, R, Terrenzio, C, Uva, P, Watson, C, White, S, Boggi U., Vistoli F., Marchetti P., Kandaswamy R., Berney T., Andres A., Arbogast H. P., Badet L., Baronti W., Bartlett S. T., Benedetti E., Branchereau J., Burke G. W. 3., Buron F., Caldara R., Cardillo M., Casanova D., Cipriani F., Cooper M., Cupisti A., de Koning E. J. P., Davide J., Drachenberg C., Ettorre G. M., Fernandez Cruz L., Fridell J. A., Friend P. J., Furian L., Gaber O. A., Gruessner A. C., Gruessner R. W. G., Gunton J. E., Han D. -J., Iacopi S., Kauffmann E. F., Kaufman D., Kenmochi T., Khambalia H. A., Lai Q., Langer R. M., Maffi P., Marselli L., Menichetti F., Miccoli M., Mittal S., Morelon E., Napoli N., Neri F., Oberholzer J., Odorico J. S., Ollinger R., Oniscu G., Orlando G., Ortenzi M., Perosa M., Perrone V. G., Redfield R. R., Ricci C., Rigotti P., Robertson R. P., Ross L. F., Rossi M., Saudek F., Scalea J. R., Schenker P., Secchi A., Socci C., Sousa Silva D., Squifflet J. P., Stock P. G., Stratta R. J., Terrenzio C., Uva P., Watson C. C. E., White S. A., Boggi, U, Vistoli, F, Marchetti, P, Kandaswamy, R, Berney, T, Andres, A, Arbogast, H, Badet, L, Baronti, W, Bartlett, S, Benedetti, E, Branchereau, J, Burke, G, Buron, F, Caldara, R, Cardillo, M, Casanova, D, Cipriani, F, Cooper, M, Cupisti, A, de Koning, E, Davide, J, Drachenberg, C, Ettorre, G, Fernandez Cruz, L, Fridell, J, Friend, P, Furian, L, Gaber, O, Gruessner, A, Gruessner, R, Gunton, J, Han, D, Iacopi, S, Kauffmann, E, Kaufman, D, Kenmochi, T, Khambalia, H, Lai, Q, Langer, R, Maffi, P, Marselli, L, Menichetti, F, Miccoli, M, Mittal, S, Morelon, E, Napoli, N, Neri, F, Oberholzer, J, Odorico, J, Ollinger, R, Oniscu, G, Orlando, G, Ortenzi, M, Perosa, M, Perrone, V, Redfield, R, Ricci, C, Rigotti, P, Robertson, R, Ross, L, Rossi, M, Saudek, F, Scalea, J, Schenker, P, Secchi, A, Socci, C, Sousa Silva, D, Squifflet, J, Stock, P, Stratta, R, Terrenzio, C, Uva, P, Watson, C, White, S, Boggi U., Vistoli F., Marchetti P., Kandaswamy R., Berney T., Andres A., Arbogast H. P., Badet L., Baronti W., Bartlett S. T., Benedetti E., Branchereau J., Burke G. W. 3., Buron F., Caldara R., Cardillo M., Casanova D., Cipriani F., Cooper M., Cupisti A., de Koning E. J. P., Davide J., Drachenberg C., Ettorre G. M., Fernandez Cruz L., Fridell J. A., Friend P. J., Furian L., Gaber O. A., Gruessner A. C., Gruessner R. W. G., Gunton J. E., Han D. -J., Iacopi S., Kauffmann E. F., Kaufman D., Kenmochi T., Khambalia H. A., Lai Q., Langer R. M., Maffi P., Marselli L., Menichetti F., Miccoli M., Mittal S., Morelon E., Napoli N., Neri F., Oberholzer J., Odorico J. S., Ollinger R., Oniscu G., Orlando G., Ortenzi M., Perosa M., Perrone V. G., Redfield R. R., Ricci C., Rigotti P., Robertson R. P., Ross L. F., Rossi M., Saudek F., Scalea J. R., Schenker P., Secchi A., Socci C., Sousa Silva D., Squifflet J. P., Stock P. G., Stratta R. J., Terrenzio C., Uva P., Watson C. C. E., and White S. A.

Abstract

Comprehensive evidence-based guidelines for the practice of pancreas transplantation are yet to be established. The First World Consensus Conference on Pancreas Transplantation was convened for this purpose. A steering committee selected the participants and defined the questions to be addressed. A group of literature reviewers identified 597 studies to be included in summaries for guidelines production. Expert groups formulated the first draft of recommendations. Two rounds of discussion and voting occurred online, using the Delphi method (agreement rate ≥85%). After each round, critical responses of experts were reviewed, and recommendations were amended accordingly. Recommendations were finalized after live discussions. Each session was preceded by expert presentations and a summary of results of systematic literature review. Up to three voting rounds were allowed for each recommendation. To avoid potential conflicts of interest, deliberations on issues regarding the impact of pancreas transplantation on the management of diabetes were conducted by an independent jury. Recommendations on technical issues were determined by experts and validated using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument. Quality of evidence was assessed using the Scottish Intercollegiate Guidelines Network (SIGN) methodology. Each recommendation received a GRADE rating (Grading of Recommendations, Assessment, Development and Evaluations).

Published
2021

48. First World Consensus Conference on pancreas transplantation: Part II – recommendations

Author

Boggi, U, Vistoli, F, Andres, A, Arbogast, H, Badet, L, Baronti, W, Bartlett, S, Benedetti, E, Branchereau, J, Burke, G, Buron, F, Caldara, R, Cardillo, M, Casanova, D, Cipriani, F, Cooper, M, Cupisti, A, Davide, J, Drachenberg, C, de Koning, E, Ettorre, G, Fernandez Cruz, L, Fridell, J, Friend, P, Furian, L, Gaber, O, Gruessner, A, Gruessner, R, Gunton, J, Han, D, Iacopi, S, Kauffmann, E, Kaufman, D, Kenmochi, T, Khambalia, H, Lai, Q, Langer, R, Maffi, P, Marselli, L, Menichetti, F, Miccoli, M, Mittal, S, Morelon, E, Napoli, N, Neri, F, Oberholzer, J, Odorico, J, Ollinger, R, Oniscu, G, Orlando, G, Ortenzi, M, Perosa, M, Perrone, V, Pleass, H, Redfield, R, Ricci, C, Rigotti, P, Paul Robertson, R, Ross, L, Rossi, M, Saudek, F, Scalea, J, Schenker, P, Secchi, A, Socci, C, Sousa Silva, D, Squifflet, J, Stock, P, Stratta, R, Terrenzio, C, Uva, P, Watson, C, White, S, Marchetti, P, Kandaswamy, R, Berney, T, Boggi U., Vistoli F., Andres A., Arbogast H. P., Badet L., Baronti W., Bartlett S. T., Benedetti E., Branchereau J., Burke G. W., Buron F., Caldara R., Cardillo M., Casanova D., Cipriani F., Cooper M., Cupisti A., Davide J., Drachenberg C., de Koning E. J. P., Ettorre G. M., Fernandez Cruz L., Fridell J. A., Friend P. J., Furian L., Gaber O. A., Gruessner A. C., Gruessner R. W. G., Gunton J. E., Han D. -J., Iacopi S., Kauffmann E. F., Kaufman D., Kenmochi T., Khambalia H. A., Lai Q., Langer R. M., Maffi P., Marselli L., Menichetti F., Miccoli M., Mittal S., Morelon E., Napoli N., Neri F., Oberholzer J., Odorico J. S., Ollinger R., Oniscu G., Orlando G., Ortenzi M., Perosa M., Perrone V. G., Pleass H., Redfield R. R., Ricci C., Rigotti P., Paul Robertson R., Ross L. F., Rossi M., Saudek F., Scalea J. R., Schenker P., Secchi A., Socci C., Sousa Silva D., Squifflet J. P., Stock P. G., Stratta R. J., Terrenzio C., Uva P., Watson C. C. E., White S. A., Marchetti P., Kandaswamy R., Berney T., Boggi, U, Vistoli, F, Andres, A, Arbogast, H, Badet, L, Baronti, W, Bartlett, S, Benedetti, E, Branchereau, J, Burke, G, Buron, F, Caldara, R, Cardillo, M, Casanova, D, Cipriani, F, Cooper, M, Cupisti, A, Davide, J, Drachenberg, C, de Koning, E, Ettorre, G, Fernandez Cruz, L, Fridell, J, Friend, P, Furian, L, Gaber, O, Gruessner, A, Gruessner, R, Gunton, J, Han, D, Iacopi, S, Kauffmann, E, Kaufman, D, Kenmochi, T, Khambalia, H, Lai, Q, Langer, R, Maffi, P, Marselli, L, Menichetti, F, Miccoli, M, Mittal, S, Morelon, E, Napoli, N, Neri, F, Oberholzer, J, Odorico, J, Ollinger, R, Oniscu, G, Orlando, G, Ortenzi, M, Perosa, M, Perrone, V, Pleass, H, Redfield, R, Ricci, C, Rigotti, P, Paul Robertson, R, Ross, L, Rossi, M, Saudek, F, Scalea, J, Schenker, P, Secchi, A, Socci, C, Sousa Silva, D, Squifflet, J, Stock, P, Stratta, R, Terrenzio, C, Uva, P, Watson, C, White, S, Marchetti, P, Kandaswamy, R, Berney, T, Boggi U., Vistoli F., Andres A., Arbogast H. P., Badet L., Baronti W., Bartlett S. T., Benedetti E., Branchereau J., Burke G. W., Buron F., Caldara R., Cardillo M., Casanova D., Cipriani F., Cooper M., Cupisti A., Davide J., Drachenberg C., de Koning E. J. P., Ettorre G. M., Fernandez Cruz L., Fridell J. A., Friend P. J., Furian L., Gaber O. A., Gruessner A. C., Gruessner R. W. G., Gunton J. E., Han D. -J., Iacopi S., Kauffmann E. F., Kaufman D., Kenmochi T., Khambalia H. A., Lai Q., Langer R. M., Maffi P., Marselli L., Menichetti F., Miccoli M., Mittal S., Morelon E., Napoli N., Neri F., Oberholzer J., Odorico J. S., Ollinger R., Oniscu G., Orlando G., Ortenzi M., Perosa M., Perrone V. G., Pleass H., Redfield R. R., Ricci C., Rigotti P., Paul Robertson R., Ross L. F., Rossi M., Saudek F., Scalea J. R., Schenker P., Secchi A., Socci C., Sousa Silva D., Squifflet J. P., Stock P. G., Stratta R. J., Terrenzio C., Uva P., Watson C. C. E., White S. A., Marchetti P., Kandaswamy R., and Berney T.

Abstract

The First World Consensus Conference on Pancreas Transplantation provided 49 jury deliberations regarding the impact of pancreas transplantation on the treatment of diabetic patients, and 110 experts’ recommendations for the practice of pancreas transplantation. The main message from this consensus conference is that both simultaneous pancreas-kidney transplantation (SPK) and pancreas transplantation alone can improve long-term patient survival, and all types of pancreas transplantation dramatically improve the quality of life of recipients. Pancreas transplantation may also improve the course of chronic complications of diabetes, depending on their severity. Therefore, the advantages of pancreas transplantation appear to clearly surpass potential disadvantages. Pancreas after kidney transplantation increases the risk of mortality only in the early period after transplantation, but is associated with improved life expectancy thereafter. Additionally, preemptive SPK, when compared to SPK performed in patients undergoing dialysis, appears to be associated with improved outcomes. Time on dialysis has negative prognostic implications in SPK recipients. Increased long-term survival, improvement in the course of diabetic complications, and amelioration of quality of life justify preferential allocation of kidney grafts to SPK recipients. Audience discussions and live voting are available online at the following URL address: http://mediaeventi.unipi.it/category/1st-world-consensus-conference-of-pancreas-transplantation/246.

Published
2021

49. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy

Author

De'Angelis, N, Catena, F, Memeo, R, Coccolini, F, Martinez-Perez, A, Romeo, O, De Simone, B, Di Saverio, S, Brustia, R, Rhaiem, R, Piardi, T, Conticchio, M, Marchegiani, F, Beghdadi, N, Abu-Zidan, F, Alikhanov, R, Allard, M, Allievi, N, Amaddeo, G, Ansaloni, L, Andersson, R, Andolfi, E, Azfar, M, Bala, M, Benkabbou, A, Ben-Ishay, O, Bianchi, G, Biffl, W, Brunetti, F, Carra, M, Casanova, D, Celentano, V, Ceresoli, M, Chiara, O, Cimbanassi, S, Bini, R, Coimbra, R, Luigi de'Angelis, G, Decembrino, F, De Palma, A, de Reuver, P, Domingo, C, Cotsoglou, C, Ferrero, A, Fraga, G, Gaiani, F, Gheza, F, Gurrado, A, Harrison, E, Henriquez, A, Hofmeyr, S, Iadarola, R, Kashuk, J, Kianmanesh, R, Kirkpatrick, A, Kluger, Y, Landi, F, Langella, S, Lapointe, R, Le Roy, B, Luciani, A, Machado, F, Maggi, U, Maier, R, Mefire, A, Hiramatsu, K, Ordonez, C, Patrizi, F, Planells, M, Peitzman, A, Pekolj, J, Perdigao, F, Pereira, B, Pessaux, P, Pisano, M, Puyana, J, Rizoli, S, Portigliotti, L, Romito, R, Sakakushev, B, Sanei, B, Scatton, O, Serradilla-Martin, M, Schneck, A, Sissoko, M, Sobhani, I, ten Broek, R, Testini, M, Valinas, R, Veloudis, G, Vitali, G, Weber, D, Zorcolo, L, Giuliante, F, Gavriilidis, P, Fuks, D, Sommacale, D, de'Angelis N., Catena F., Memeo R., Coccolini F., Martinez-Perez A., Romeo O. M., De Simone B., Di Saverio S., Brustia R., Rhaiem R., Piardi T., Conticchio M., Marchegiani F., Beghdadi N., Abu-Zidan F. M., Alikhanov R., Allard M. -A., Allievi N., Amaddeo G., Ansaloni L., Andersson R., Andolfi E., Azfar M., Bala M., Benkabbou A., Ben-Ishay O., Bianchi G., Biffl W. L., Brunetti F., Carra M. C., Casanova D., Celentano V., Ceresoli M., Chiara O., Cimbanassi S., Bini R., Coimbra R., Luigi de'Angelis G., Decembrino F., De Palma A., de Reuver P. R., Domingo C., Cotsoglou C., Ferrero A., Fraga G. P., Gaiani F., Gheza F., Gurrado A., Harrison E., Henriquez A., Hofmeyr S., Iadarola R., Kashuk J. L., Kianmanesh R., Kirkpatrick A. W., Kluger Y., Landi F., Langella S., Lapointe R., Le Roy B., Luciani A., Machado F., Maggi U., Maier R. V., Mefire A. C., Hiramatsu K., Ordonez C., Patrizi F., Planells M., Peitzman A. B., Pekolj J., Perdigao F., Pereira B. M., Pessaux P., Pisano M., Puyana J. C., Rizoli S., Portigliotti L., Romito R., Sakakushev B., Sanei B., Scatton O., Serradilla-Martin M., Schneck A. -S., Sissoko M. L., Sobhani I., ten Broek R. P., Testini M., Valinas R., Veloudis G., Vitali G. C., Weber D., Zorcolo L., Giuliante F., Gavriilidis P., Fuks D., Sommacale D., De'Angelis, N, Catena, F, Memeo, R, Coccolini, F, Martinez-Perez, A, Romeo, O, De Simone, B, Di Saverio, S, Brustia, R, Rhaiem, R, Piardi, T, Conticchio, M, Marchegiani, F, Beghdadi, N, Abu-Zidan, F, Alikhanov, R, Allard, M, Allievi, N, Amaddeo, G, Ansaloni, L, Andersson, R, Andolfi, E, Azfar, M, Bala, M, Benkabbou, A, Ben-Ishay, O, Bianchi, G, Biffl, W, Brunetti, F, Carra, M, Casanova, D, Celentano, V, Ceresoli, M, Chiara, O, Cimbanassi, S, Bini, R, Coimbra, R, Luigi de'Angelis, G, Decembrino, F, De Palma, A, de Reuver, P, Domingo, C, Cotsoglou, C, Ferrero, A, Fraga, G, Gaiani, F, Gheza, F, Gurrado, A, Harrison, E, Henriquez, A, Hofmeyr, S, Iadarola, R, Kashuk, J, Kianmanesh, R, Kirkpatrick, A, Kluger, Y, Landi, F, Langella, S, Lapointe, R, Le Roy, B, Luciani, A, Machado, F, Maggi, U, Maier, R, Mefire, A, Hiramatsu, K, Ordonez, C, Patrizi, F, Planells, M, Peitzman, A, Pekolj, J, Perdigao, F, Pereira, B, Pessaux, P, Pisano, M, Puyana, J, Rizoli, S, Portigliotti, L, Romito, R, Sakakushev, B, Sanei, B, Scatton, O, Serradilla-Martin, M, Schneck, A, Sissoko, M, Sobhani, I, ten Broek, R, Testini, M, Valinas, R, Veloudis, G, Vitali, G, Weber, D, Zorcolo, L, Giuliante, F, Gavriilidis, P, Fuks, D, Sommacale, D, de'Angelis N., Catena F., Memeo R., Coccolini F., Martinez-Perez A., Romeo O. M., De Simone B., Di Saverio S., Brustia R., Rhaiem R., Piardi T., Conticchio M., Marchegiani F., Beghdadi N., Abu-Zidan F. M., Alikhanov R., Allard M. -A., Allievi N., Amaddeo G., Ansaloni L., Andersson R., Andolfi E., Azfar M., Bala M., Benkabbou A., Ben-Ishay O., Bianchi G., Biffl W. L., Brunetti F., Carra M. C., Casanova D., Celentano V., Ceresoli M., Chiara O., Cimbanassi S., Bini R., Coimbra R., Luigi de'Angelis G., Decembrino F., De Palma A., de Reuver P. R., Domingo C., Cotsoglou C., Ferrero A., Fraga G. P., Gaiani F., Gheza F., Gurrado A., Harrison E., Henriquez A., Hofmeyr S., Iadarola R., Kashuk J. L., Kianmanesh R., Kirkpatrick A. W., Kluger Y., Landi F., Langella S., Lapointe R., Le Roy B., Luciani A., Machado F., Maggi U., Maier R. V., Mefire A. C., Hiramatsu K., Ordonez C., Patrizi F., Planells M., Peitzman A. B., Pekolj J., Perdigao F., Pereira B. M., Pessaux P., Pisano M., Puyana J. C., Rizoli S., Portigliotti L., Romito R., Sakakushev B., Sanei B., Scatton O., Serradilla-Martin M., Schneck A. -S., Sissoko M. L., Sobhani I., ten Broek R. P., Testini M., Valinas R., Veloudis G., Vitali G. C., Weber D., Zorcolo L., Giuliante F., Gavriilidis P., Fuks D., and Sommacale D.

Abstract

Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4–1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.

Published
2021

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