212 results on '"Caselli, Gianfranco"'
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2. A first-in-human trial on the safety and immunogenicity of COVID-eVax, a cellular response-skewed DNA vaccine against COVID-19
3. COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models
4. CR10049, THE FIRST OA-TARGETED KINASE INHIBITOR, IMPROVES PAIN BEHAVIOUR, RESOLVES INFLAMMATION AND PRESERVES JOINT STRUCTURE IN SMALL AND LARGE ANIMAL MODELS
5. IL-18 cDNA Vaccination Protects Mice from Spontaneous Lupus-like Autoimmune Disease
6. A first-in-human trial on the safety and immunogenicity of COVID-eVax, a cellular response-skewed DNA vaccine against COVID-19
7. Synthesis and structure–activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold
8. Synthesis and structure–activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds
9. Modulation of NMDA receptor activity by CR4056, an imidazoline-2 receptor ligand with analgesic properties
10. Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
11. I2-Imidazoline Ligand CR4056 Improves Memory, Increases ApoE Expression and Reduces BBB Leakage in 5xFAD Mice
12. CR13626: a novel oral brain penetrant tyrosine kinase inhibitor that reduces tumor growth and prolongs survival in a mouse model of glioblastoma
13. In vivo neurochemical effects of the NR2B selective NMDA receptor antagonist CR 3394 in 6-hydroxydopamine lesioned rats
14. Efficacy of CR3294, a new benzamidine derivative, in the prevention of 5-fluorouracil-induced gastrointestinal mucositis and diarrhea in mice
15. Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats
16. Toxicity and Local Tolerance of COVID- eVax, a Plasmid DNA Vaccine for SARS-CoV-2, Delivered by Electroporation
17. CR13626: a novel oral brain penetrant tyrosine kinase inhibitor that reduces tumor growth and prolongs survival in a mouse model of glioblastoma
18. COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19
19. Functional in vitro characterization of CR 3394: A novel voltage dependent N-methyl- d-aspartate (NMDA) receptor antagonist
20. Abstract 4219: Efficacy of CR13626, a novel oral brain penetrant multi-kinase inhibitor, in a mouse model of glioblastoma
21. Abstract 2208: Combination of the EP4 antagonist CR6086 and anti-PD-1 monoclonal antibody inhibits tumor growth in a microsatellite stable colorectal cancer in mice
22. Improved efficacy, tolerance, safety, and abuse liability profile of the combination of CR4056 and morphine over morphine alone in rodent models
23. Antipsychotic-like effects of the N-methyl-d-aspartate receptor modulator neboglamine: An immunohistochemical and behavioural study in the rat
24. LB-005 - CR10049, THE FIRST OA-TARGETED KINASE INHIBITOR, IMPROVES PAIN BEHAVIOUR, RESOLVES INFLAMMATION AND PRESERVES JOINT STRUCTURE IN SMALL AND LARGE ANIMAL MODELS.
25. Pharmacological profile of CR3465, a new leukotriene CysLT 1 receptor antagonist with broad anti-inflammatory activity
26. Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity
27. Toxicity and Local Tolerance of COVID- e Vax, a Plasmid DNA Vaccine for SARS-CoV-2, Delivered by Electroporation.
28. Thioredoxin, a Redox Enzyme Released in Infection and Inflammation, Is a Unique Chemoattractant for Neutrophils, Monocytes, and T Cells
29. CR4056, a powerful analgesic imidazoline‐2 receptor ligand, inhibits the inflammation‐induced PKCε phosphorylation and membrane translocation in sensory neurons
30. Selective inhibition of interleukin-8-induced neutrophil chemotaxis by ketoprofen isomers
31. Additional file 3: of Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
32. Additional file 1: of Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
33. Additional file 4: of Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
34. Additional file 2: of Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
35. LPS INDUCES IL-6 IN THE BRAIN AND IN SERUM LARGELY THROUGH TNF PRODUCTION
36. Synthesis, inhibitory activity towards human leukocyte elastase and molecular modelling studies of 1-carbamoyl-4-methyleneaminoxyazetidinones
37. Functionalization of protein hexahistidine tags by functional nanoreactors
38. Nanoreactors for the multi-functionalization of poly-histidine fragments
39. Phenylindenone isomers as divergent modulators of p38α MAP kinase
40. Does Colchicine Really Induce Bone Formation in the Rodent Bone Marrow? Yes, it Does
41. Synthesis and in vitro and in vivo evaluation of the 2-(6′methoxy-3′,4′-dihydro-1′-naphtyl)-4H-3,1-benzoxazin-4-one as a new potent substrate inhibitor of human leukocyte elastase
42. Peripheral blood mononuclear cell production of interleukin-8 and IL-8-dependent neutrophil function in hypercholesterolemic patients
43. Development of subnanomolar-affinity serotonin 5-HT4 receptor ligands based on quinoline structures
44. Poly-histidine grafting leading to fishbone-like architectures
45. Development of Imidazole-Reactive Molecules Leading to a New Aggregation-Induced Emission Fluorophore Based on the Cinnamic Scaffold
46. Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis
47. CR4056, a powerful analgesic imidazoline-2 receptor ligand, inhibits the inflammation-induced PKCε phosphorylation and membrane translocation in sensory neurons.
48. Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis
49. Multivalent ligands for the serotonin 5-HT4 receptor
50. Discovery, synthesis, selectivity modulation and DMPK characterization of 5-azaspiro[2.4]heptanes as potent orexin receptor antagonists
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