594 results on '"Casewell, Nicholas R."'
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2. Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies
3. Development of a membrane-disruption assay using phospholipid vesicles as a proxy for the detection of cellular membrane degradation
4. Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms
5. Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL
6. High throughput identification of human monoclonal antibodies and heavy-chain-only antibodies to treat snakebite
7. Snake Identification in the Ancient Egyptian Brooklyn Medical Papyrus : A New Study of the Twenty-Four Extant Registers of the 'Snakebite Papyrus'
8. An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules
9. A comparative genomics multitool for scientific discovery and conservation
10. A global core outcome measurement set for snakebite clinical trials
11. Snake Identification in the Ancient Egyptian Brooklyn Medical Papyrus
12. Proteomics and histological assessment of an organotypic model of human skin following exposure to Naja nigricollis venom
13. Keel venom: Rhabdophis subminiatus (Red-Necked Keelback) venom pathophysiologically affects diverse blood clotting pathways
14. In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus
15. Physiological constraints dictate toxin spatial heterogeneity in snake venom glands
16. Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition
17. The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors
18. Nanofractionation Analytics for Comparing MALDI-MS and ESI-MS Data of Viperidae Snake Venom Toxins.
19. Importance of the Cysteine-Rich Domain of Snake Venom Prothrombin Activators: Insights Gained from Synthetic Neutralizing Antibodies.
20. Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming.
21. Improving in vivo assays in snake venom and antivenom research: A community discussion
22. Intraspecific venom variation in the medically important puff adder (Bitis arietans): comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom
23. African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages
24. Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins
25. Snakebite prevalence and risk factors in a nomadic population in Samburu County, Kenya: A community-based survey
26. Preclinical Evaluation of the Neutralising Efficacy of Three Monospecific Antivenoms Against the Venoms of Five African Echis Species, Including the Recently Partitioned E. Ocellatus and E. Romani
27. Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals
28. Erythrocyte haemotoxicity profiling of snake venom toxins after nanofractionation
29. Derivation of snake venom gland organoids for in vitro venom production
30. Investigating Snake-Venom-Induced Dermonecrosis and Inflammation Using an Ex Vivo Human Skin Model.
31. Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib.
32. Development of high-throughput screening assays for profiling snake venom phospholipase A2 activity after chromatographic fractionation
33. Isolation and characterization of cytotoxic and insulin-releasing components from the venom of the black-necked spitting cobra Naja nigricollis (Elapidae)
34. Venomics of the asp viper Vipera aspis aspis from France
35. Development of a generic high-throughput screening assay for profiling snake venom protease activity after high-resolution chromatographic fractionation
36. Snake Venom Metalloproteinases
37. ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming
38. Snakebite epidemiology, outcomes and multi-cluster risk modelling in Eswatini
39. ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming
40. Author Correction: A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite
41. Genome-wide data implicate terminal fusion automixis in king cobra facultative parthenogenesis
42. Intact protein mass spectrometry reveals intraspecies variations in venom composition of a local population of Vipera kaznakovi in Northeastern Turkey
43. Defining the pathogenic threat of envenoming by South African shield-nosed and coral snakes (genus Aspidelaps), and revealing the likely efficacy of available antivenom
44. Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors.
45. Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform.
46. Analytical Size Exclusion Chromatography Coupled with Mass Spectrometry in Parallel with High-Throughput Venomics and Bioassaying for Venom Profiling
47. Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms
48. Dermonecrosis caused by spitting cobra snakebite is the result of toxin potentiation and is prevented by the repurposed drug varespladib
49. A long-term observational study of paediatric snakebite in Kilifi County, south-east Kenya
50. Evolution of the Snake Venom Delivery System
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