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12. Evaluation of the LMA CTrach

Author

Cattano, D., Pesetti, B., Di Salvo, C., Giunta, F., Liu, E. H. C., Goy, R. W. L., and Chen, F. G.

Published
2007

14. Perioperative management of obstructive sleep apnea: A systematic review

Author

Corso, R, Russotto, V, Gregoretti, C, Cattano, D, Corso, R, Russotto, V, Gregoretti, C, and Cattano, D

Abstract

INTRODUCTION: Obstructive sleep apnea (OSA) is the leading sleep disordered breathing condition, with a prevalence rate of moderate to severe OSA of approximately 10-17% in the general population. EVIDENCE ACQUISITION: We performed an Ovid-Medline search of all articles published up to August 2016. We included all articles providing updated evidence on epidemiology, pathophysiologic mechanisms and perioperative interventions. EVIDENCE SYNTHESIS: OSA is associated with a number of comorbidities and increased perioperative risks. Although in-laboratory polysomnography represents the gold-standard for diagnosis of OSA, it is costly and time-consuming. Anesthesiologists may screen patients for OSA through one of the available questionnaires, of which the snoring, tiredness, observed apnea, high blood pressure (STOP)-Body Mass Index, age, neck circumference and gender (Bang), STOP-bang questionnaire is the most externally validated. Although its sensitivity for the identification of mild OSA patients is 83.6%, its specificity is only 56.4%. OSA patients are associated with a higher risk of both difficult ventilation and intubation. However, practice guidelines refer to available guidelines for difficult airway management. Perioperative continuous positive airway pressure use may be of benefit since it has been reported to be associated with a reduction of both respiratory and cardiovascular complications and symptom relief. When feasible, regional anesthesia techniques and a multimodal analgesia approach should be adopted to reduce intraoperative and postoperative exposure to opioids. CONCLUSIONS: Preoperative screening of OSA patients is of relevance given the increased perioperative morbidity of these patients. Further studies are needed to provide conclusive data on which perioperative interventions are most effective at reducing this risk.

Published
2018

17. To be awake or not to be

Author

Cattano, D.

Subjects
Anesthesia -- Methods, Anesthesia -- Health aspects, Patients -- Care and treatment, Patients -- Health aspects, Surgery -- Health aspects
Abstract

Byline: D. Cattano The standard of care of patients receiving regional anesthesia has changed in the last 10 years dramatically. The perception about the need for supplemental analgo-sedation, however, from [...]

Published
2009

20. Nitrous oxide discretely up-regulates nNOS and p53 in neonatal rat brain

Author

Cattano, D., Valleggi, S., Abramo, A., Francesco Forfori, Maze, M., and FRANCESCO GIUNTA

Subjects
Rats, Sprague-Dawley, Animals, Newborn, Transcription, Genetic, Nitrous Oxide, Animals, Brain, Nitric Oxide Synthase Type II, Apoptosis, Nitric Oxide Synthase Type I, Genes, p53, Rats, Up-Regulation
Abstract

Animal studies suggest that neuronal cell death often results from anesthetic administration during synaptogenesis. Volatile anesthetics are strongly involved in triggering neuronal apoptosis, whereas other inhalational agents (xenon) demonstrate protective effects. Nitrous oxide (N2O) has modest pro-apoptotic effects on its own and potent, synergistic toxic effects when combined with volatile agents. Recent findings suggest that, during periods of rapid brain development, the enhanced neurodegeneration triggered by anesthetic drugs may be caused by a compensatory increase in intracellular free calcium, a potent activator of neuronal nitric oxide synthase (nNOS). Anesthesia-induced neuro-apoptosis is also activated via the intrinsic and the extrinsic apoptotic pathways because both pathways involve p53, a key regulatory gene. The molecular events related to neuronal cell apoptosis are not completely understood. To gain further insight into the events underlying neuro-apoptosis, we analyzed the transcriptional consequences of N2O exposure on nNOS, iNOS and p53 mRNA levels.The study used 2 groups of postnatal day seven Sprague/Dawley rats (N=6 each) that were exposed for 120 minutes to air (75% N2, 25% O2) or N2O (75% N2O, 25% O2; this N2O concentration is commonly used to induce anesthesia and has been demonstrated to trigger neurodegeneration in postnatal day seven rats). Total RNA was isolated from each brain and expression analyses on iNOS and nNOS transcripts were performed using relative Real-Time C-reactive protein PCR (using G3PDH as a housekeeping gene). A semi-quantitative RT-PCR analysis was performed on the p53 transcript (using Ciclophylin A as a housekeeping gene).Statistical analysis (REST 2005) revealed a significant, 11-fold up-regulation (P=0.026) of the nNOS transcript but no significant changes in iNOS transcription. The p53 mRNA was up-regulated almost 2-fold (P=0.0002; Student's t-Test; GraphPad Prism 4.00) in N2O-treated samples relative to room-air samples.Our preliminary data show that N2O induced a selective increase in nNOS and p53 transcription. These new findings provide evidence of pro-apoptotic action by N2O and may shed new insight on its toxic effects; however, further investigations are necessary.

Published
2010

22. Recommendations for airway control and difficult airway management in thoracic aneshtesia and lung separation procedures

Author

Merli, G, Guarino, A., Della Rocca, G, Frova, G, Petrini, F, Sorbello, M, Coccia, C, Accorsi, A, Adrario, E, Agro, F, Amicucci, G, Antonelli, M, Azzeri, F, Baroncini, S, Bettelli, G, Biolcati, F, Cafaggi, C, Cattano, D, Chinelli, E, Collavo, T, Corbanese, U, Corso, R, di Filippo, A, di Giacinto, I, Donato, P, Facco, E, Favaro, R, Ferraro, F, Finco, G, Galante, D, Gattinoni, L, Giunta, F, Giurati, G, Giusti, F, Guarino, A, Ian-Nuzzi, E, Ivani, G, Ledda, G, Marchi, A, Mattioli, V, Menarini, M, Miceli, L, Mondello, E, Morossi, M, Oligeri, M, Pala, F, Pesetti, B, Pigna, A, Pittoni, G, Ripamonti, D, Rosa, G, Rosi, R, Salvo, I, Santangelo, E, Sarti, A, Scoponi, M, Serafini, G, Tana, F, Tufano, R, Vesconi, S, Villani, A, and Zauli, M.

Published
2009

24. Recommendations for airway control and difficult airway management in thoracic anesthesia and lung separation procedures

Author

Accorsi, A, Adrario, E, Agrò, F, Amicucci, G, Antonelli, M, Azzeri, F, Baroncini, S, Bettelli, G, Biolcati, F, Cafaggi, C, Cattano, D, Chinelli, E, Collavo, T, Corbanese, U, Corso, Ruggero Massimo, Della Rocca, G, Di Filippo, Alessandro, Di Giacinto, I, Donato, P, Facco, E, Favaro, R, Ferraro, F, Finco, G, Frova, G, Galante, D, Gattinoni, L, Giunta, F, Giurati, G, Giusti, F, Guarino, A, Iannuzzi, E, Ivani, G, Ledda, G, Marchi, A, Mattioli, V, Menarini, M, Merli, G, Miceli, L, Mondello, E, Morossi, M, Oligeri, M, Pala, F, Pesetti, B, Petrini, F, Pigna, A, Pittoni, G, Ripamonti, D, Rosa, G, Rosi, R, Salvo, I, Santangelo, E, Sarti, A, Scoponi, M, Serafini, G, Sorbello, Massimiliano, Tana, F, Tufano, R, Vesconi, S, Villani, A, and Zauli, M.

Subjects
Anesthesia, General, Humans, Lung, Respiration, Artificial, Thoracic Surgical Procedures
Published
2009

28. Recommendations for airway control and difficult airway management

Author

Petrini, F., Accorsi, A., Adrario, E., Agro, F., Amicucci, G., Antonelli, M., Azzeri, F., Baroncini, S., Bettelli, G., Cafaggi, C., Cattano, D., Chinelli, E., Corbanese, U., Corso, R., Della Puppa, A., Di Filippo, A., Facco, E., Favaro, Roberto, Favero, R., Frova, G., Giunta, F., Giurati, G., Giusti, F., Guarino, A., Iannuzzi, E., Ivani, G., Mazzon, D., Menarini, M., Merli, G., Mondello, E., Muttini, S., Nardi, G., Pigna, A., Pittoni, G., Ripamonti, D., Rosa, Giovanni, Rosi, R., Salvo, I., Sarti, A., Serafini, G., Servadio, G., Sgandurra, A., Sorbello, M., Tana, F., Tufano, R., Vesconi, S., Villani, A., Zauli, M., vie Aeree Difficili Gruppo Di Studio Siaarti, Sarnepi Task Force, Irc E., F., Petrini, A., Accorsi, E., Adrario, F., Agrò, G., Amicucci, M., Antonelli, F., Azzeri, S., Baroncini, G., Bettelli, C., Cafaggi, D., Cattano, E., Chinelli, U., Corbanese, R., Corso, A., Della Puppa, A., Di Filippo, E., Facco, R., Favaro, R., Favero, G., Frova, F., Giunta, G., Giurati, F., Giusti, A., Guarino, E., Iannuzzi, G., Ivani, D., Mazzon, M., Menarini, G., Merli, E., Mondello, S., Muttini, G., Nardi, A., Pigna, G., Pittoni, D., Ripamonti, G., Rosa, R., Rosi, I., Salvo, A., Sarti, G., Serafini, G., Servadio, A., Sgandurra, M., Sorbello, F., Tana, Tufano, Rosalba, S., Vesconi, A., Villani, M., Zauli, Gruppo di, Studio, and I. R., C.

Subjects
pediatric patient, vie aeree, Laryngoscopy, Intubation, Intratracheal, Humans, Anesthesia, Inhalation, Intraoperative Complications, Algorithms
Published
2005

29. Recommendations for airway control and difficult airway management

Author

Petrini, F, Accorsi, A, Adrario, E, Agro, F, Amicucci, G, Antonelli, M, Azzeri, F, Baroncini, S, Bettelli, G, Cafaggi, C, Cattano, D, Chinelli, E, Corbanese, U, Corso, R, Della, P. A, Filippo, Di, A, Facco, Enrico, Favaro, E, Favero, R, Frova, R, Giunta, G, Giurati, F, Giusti, G, Guarino, F, Iannuzzi, A, Ivani, E, Mazzon, G, Menarini, D, Merli, M, Mondello, G, Muttini, E, Nardi, S, Pigna, G, Pittoni, A, Ripamonti, G, Rosa, D, Rosi, G, Salvo, R, Sarti, I, Serafini, A, Servadio, G, Sgandurra, G, Sorbello, A, Tana, M, Tufano, F, Vesconi, R, Villani, S, and Zauli, A

Published
2005

31. Recommendations for airway control and difficult airway management. Minerva Anestesiol. 2005 Nov;71(11):617-57

Author

Petrini, F, Accorsi, A, Adrario, E, Agro, F, Amicucci, G, Antonelli, M, Azzeri, F, Baroncini, S, Bettelli, G, Cafaggi, C, Cattano, D, Chinelli, E, Corbanese, U, Corso, R, DELLA PUPPA, A, DI FILIPPO, A, Facco, E, Favaro, Roberto, Favero, R, Frova, G, Giunta, F, Giurati, G, Giusti, F, Guarino, A, Iannuzzi, E, Ivani, G, Mazzon, D, Menarini, M, Merli, G, Mondello, E, Muttini, S, Nardi, G, Pigna, A, Pittoni, G, Ripamonti, D, Rosa, Giovanni, Rosi, R, Salvo, I, Sarti, A, Serafini, G, Servadio, G, Sgandurra, A, Sorbello, M, Tana, F, Tufano, R, Vesconi, S, Villani, A, Zauli, M, GRUPPO DI STUDIO SIAARTI VIE AEREE, Difficili, Sarnepi, IRC E., and Task, Force

Published
2005

34. Anticipation of the Difficult Airway

Author

Cattano, D., primary, Killoran, P. V., additional, Iannucci, D., additional, Maddukuri, V., additional, Altamirano, A. V., additional, Sridhar, S., additional, Seitan, C., additional, Chen, Z., additional, and Hagberg, C. A., additional

Published
2014
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45. Recommendations for airway control and difficult airway management in thoracic anesthesia and lung separation procedures | Raccomandazioni per il controllo delle vie aeree e la gestione delle difficoltá in anestesia toracica e separazione polmonare

Author

Merli, G., Guarino, A., Della Rocca, G., Frova, G., Petrini, F., Sorbello, M., Coccia, C., Accorsi, A., Adrario, E., Agro, F., Amicucci, G., Antonelli, M., Azzeri, F., Baroncini, S., Bettelli, G., Biolcati, F., Cafaggi, C., Cattano, D., Chinelli, E., Collavo, T., Corbanese, U., Corso, R., Alessandro Di Filippo, Di Giacinto, I., Donato, P., Facco, E., Favaro, R., Ferraro, F., Finco, G., Galante, D., Gattinoni, L., Giunta, F., Giurati, G., Giusti, F., Ian-Nuzzi, E., Ivani, G., Ledda, G., Marchi, A., Mattioli, V., Menarini, M., Miceli, L., Mondello, E., Morossi, M., Oligeri, M., Pala, F., Pesetti, B., Pigna, A., Pittoni, G., Ripamonti, D., Rosa, G., Rosi, R., Salvo, I., Santangelo, E., Sarti, A., Scoponi, M., Serafini, G., Tana, F., Tufano, R., Vesconi, S., Villani, A., Zauli, M., Merli, G., Guarino, A., Della Rocca, G., Frova, G., Petrini, F., Sorbello, M., Coccia, C., Accorsi, A., Adrario, E., Agro, F., Amicucci, G., Antonelli, M., Azzeri, F., Baroncini, S., Bettelli, G., Biolcati, F., Cafaggi, C., Cattano, D., Chinelli, E., Collavo, T., Corbanese, U., Corso, R., di Filippo, A., di Giacinto, I., Donato, P., Facco, E., Favaro, R., Ferraro, F., Finco, G., Galante, D., Gattinoni, L., Giunta, F., Giurati, G., Giusti, F., Ian Nuzzi, E., Ivani, G., Ledda, G., Marchi, A., Mattioli, V., Menarini, M., Miceli, L., Mondello, E., Morossi, M., Oligeri, M., Pala, F., Pesetti, B., Pigna, A., Pittoni, G., Ripamonti, D., Rosa, G., Rosi, R., Salvo, I., Santangelo, E., Sarti, A., Scoponi, M., Serafini, G., Tana, F., Tufano, Rosalba, Vesconi, S., Villani, A., and Zauli, M.

47. Recommendations for airway control and difficult airway management | Raccomandazioni per il controllo delle vie aeree e la gestione delle difficoltà

Author

Petrini, F., Accorsi, A., Adrario, E., Agrò, F., Amicucci, G., Antonelli, M., Azzeri, F., Baroncini, S., Bettelli, G., Cafaggi, C., Cattano, D., Chinelli, E., Corbanese, U., Corso, R., Della Puppa, A., Alessandro Di Filippo, Facco, E., Favaro, R., Favero, R., Frova, G., Giunta, F., Giurati, G., Giusti, F., Guarino, A., Iannuzzi, E., Ivani, G., Mazzon, D., Menarini, M., Merli, G., Mondello, E., Muttini, S., Nardi, G., Pigna, A., Pittoni, G., Ripamonti, D., Rosa, G., Rosi, R., Salvo, I., Sarti, A., Serafini, G., Servadio, G., Sgandurra, A., Sorbello, M., Tana, F., Tufano, R., Vesconi, S., Villani, A., and Zauli, M.

48. Recommendations for airway control and difficult airway management,Raccomandazioni per il controllo delle vie aeree e la gestione delle difficoltà

Author

Petrini, F., Accorsi, A., Adrario, E., Agrò, F., Amicucci, G., Antonelli, M., Azzeri, F., Baroncini, S., Bettelli, G., Cafaggi, C., Cattano, D., Chinelli, E., Corbanese, U., Corso, R., Della Puppa, A., Di Filippo, A., Facco, E., Favaro, R., Favero, R., Frova, G., Giunta, F., Giurati, G., Giusti, F., Guarino, A., Iannuzzi, E., Ivani, G., Mazzon, D., Menarini, M., Merli, G., Mondello, E., Muttini, S., Nardi, G., Pigna, A., Pittoni, G., Ripamonti, D., Rosa, G., Rosi, R., Salvo, I., Sarti, A., Serafini, G., Servadio, G., Sgandurra, A., Massimiliano Sorbello, Tana, F., Tufano, R., Vesconi, S., Villani, A., and Zauli, M.

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