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39 results on '"Cauzillo G"'

1. Underreporting of congenital rubella in Italy, 2010–2014

Author: Giambi, Cristina, Bella, Antonino, Filia, Antonietta, Del Manso, Martina, Nacca, Gloria, Declich, Silvia, Rota, Maria Cristina, Di Giacomo, M., Locuratolo, F., Cauzillo, G., Natter, B., Mignuoli, A., Pascucci, M. G., Frasca, G., Gallo, T., Braida, C., Vitagliano, A., Guerra, M., Scognamiglio, P., Cremonesi, I., Piatti, A., Cereda, D., Senatore, S., Fiacchini, D., Giuliani, S., Ponzio, G. V., Ferrara, L., Giovannetti, F., Prato, R., Cappelli, M. G., Palmas, M. A., Macis, F., Palermo, M., Balocchini, E., Pecori, L., Carraro, V., Zuccali, M. G., Ruffier, M., Russo, F., Zanella, F., Bano, M., Tosti, A., and Regional contact points for rubella
Published: 2017
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2. Problematic social media use: Associations with health complaints among adolescents

Author: Marino, C, Lenzi, M, Canale, N, Pierannunzio, D, Dalmasso, P, Borraccino, A, Cappello, N, Lemma, P, Vieno, A, Nardone, P, Spinelli, A, Donati, S, Pizzi, E, Ciardullo, S, Andreozzi, S, Bucciarelli, M, de Mei, B, Cattaneo, C, Cavallo, F, Piraccini, G, Berchialla, P, Charrier, L, Sciannameo, V, Gaboardi, M, Santinello, M, Lazzeri, G, Giacchi, M, Pammolli, A, Simi, R, Galeone, D, Menzano, M, Vienna, A, Colleluori, C, Di Giacomo, M, Ranalli, E, Cauzillo, G, Mininni, M, Sorrentino, G, Azzarito, C, Cernuzio, A, la Rocca, M, Pugliese, A, Mazzarella, G, Angelini, P, Fridel, M, Carletti, C, Concina, F, Ronfani, L, Pani, P, Cairella, G, Bosca, L, Pancallo, M, Ferrando, G, Celata, C, Coppola, L, Lobascio, C, Gelmi, G, Crottogini, L, Velasco, V, de Introna, S, Giostra, G, Ciallella, M, Colitti, M, Paolitto, E, Caputo, M, Stingi, D, Pacella, P, Pasquale, P, Palmas, M, Murgia, A, Cernigliaro, A, Ferro, M, Scondotto, S, Aramini, L, Corridori, V, Cristofori, M, Sorbelli, D, Giovannini, G, Covarino, A, Michieletto, F, Bino, E, Zuccali, M, Fanolla, A, Weiss, S, Marino C., Lenzi M., Canale N., Pierannunzio D., Dalmasso P., Borraccino A., Cappello N., Lemma P., Vieno A., Nardone P., Spinelli A., Donati S., Pizzi E., Ciardullo S., Andreozzi S., Bucciarelli M., de Mei B., Cattaneo C., Cavallo F., Piraccini G., Berchialla P., Charrier L., Sciannameo V., Gaboardi M., Santinello M., Lazzeri G., Giacchi M. V., Pammolli A., Simi R., Galeone D., Menzano M. T., Vienna A., Colleluori C., Di Giacomo M., Ranalli E., Cauzillo G., Mininni M., Sorrentino G., Azzarito C., Cernuzio A., la Rocca M., Pugliese A., Mazzarella G., Angelini P., Fridel M., Carletti C., Concina F., Ronfani L., Pani P., Cairella G., Bosca L., Pancallo M. T., Ferrando G., Celata C., Coppola L., Lobascio C., Gelmi G., Crottogini L., Velasco V., de Introna S., Giostra G., Ciallella M. L., Colitti M., Paolitto E., Caputo M., Stingi D., Pacella P., Pasquale P., Palmas M. A., Murgia A., Cernigliaro A., Ferro M. P., Scondotto S., Aramini L., Corridori V., Cristofori M., Sorbelli D., Giovannini G., Covarino A. M., Michieletto F., Bino E., Zuccali M. G., Fanolla A., Weiss S., Marino, C, Lenzi, M, Canale, N, Pierannunzio, D, Dalmasso, P, Borraccino, A, Cappello, N, Lemma, P, Vieno, A, Nardone, P, Spinelli, A, Donati, S, Pizzi, E, Ciardullo, S, Andreozzi, S, Bucciarelli, M, de Mei, B, Cattaneo, C, Cavallo, F, Piraccini, G, Berchialla, P, Charrier, L, Sciannameo, V, Gaboardi, M, Santinello, M, Lazzeri, G, Giacchi, M, Pammolli, A, Simi, R, Galeone, D, Menzano, M, Vienna, A, Colleluori, C, Di Giacomo, M, Ranalli, E, Cauzillo, G, Mininni, M, Sorrentino, G, Azzarito, C, Cernuzio, A, la Rocca, M, Pugliese, A, Mazzarella, G, Angelini, P, Fridel, M, Carletti, C, Concina, F, Ronfani, L, Pani, P, Cairella, G, Bosca, L, Pancallo, M, Ferrando, G, Celata, C, Coppola, L, Lobascio, C, Gelmi, G, Crottogini, L, Velasco, V, de Introna, S, Giostra, G, Ciallella, M, Colitti, M, Paolitto, E, Caputo, M, Stingi, D, Pacella, P, Pasquale, P, Palmas, M, Murgia, A, Cernigliaro, A, Ferro, M, Scondotto, S, Aramini, L, Corridori, V, Cristofori, M, Sorbelli, D, Giovannini, G, Covarino, A, Michieletto, F, Bino, E, Zuccali, M, Fanolla, A, Weiss, S, Marino C., Lenzi M., Canale N., Pierannunzio D., Dalmasso P., Borraccino A., Cappello N., Lemma P., Vieno A., Nardone P., Spinelli A., Donati S., Pizzi E., Ciardullo S., Andreozzi S., Bucciarelli M., de Mei B., Cattaneo C., Cavallo F., Piraccini G., Berchialla P., Charrier L., Sciannameo V., Gaboardi M., Santinello M., Lazzeri G., Giacchi M. V., Pammolli A., Simi R., Galeone D., Menzano M. T., Vienna A., Colleluori C., Di Giacomo M., Ranalli E., Cauzillo G., Mininni M., Sorrentino G., Azzarito C., Cernuzio A., la Rocca M., Pugliese A., Mazzarella G., Angelini P., Fridel M., Carletti C., Concina F., Ronfani L., Pani P., Cairella G., Bosca L., Pancallo M. T., Ferrando G., Celata C., Coppola L., Lobascio C., Gelmi G., Crottogini L., Velasco V., de Introna S., Giostra G., Ciallella M. L., Colitti M., Paolitto E., Caputo M., Stingi D., Pacella P., Pasquale P., Palmas M. A., Murgia A., Cernigliaro A., Ferro M. P., Scondotto S., Aramini L., Corridori V., Cristofori M., Sorbelli D., Giovannini G., Covarino A. M., Michieletto F., Bino E., Zuccali M. G., Fanolla A., and Weiss S.
Abstract: Objective. Problematic Social Media Use (PSMU) has an addictive potential for young users. The aim of this study was to show the prevalence of PSMU across Italian regions and its association with health complaints. Materials and methods. Data are gathered from the Italian 2018 Health Behaviour in School-aged Children survey using a representative sample of Italian adolescents aged 11, 13 and 15 years (50.6% males). Participants completed self-administered questionnaires assessing PSMU and health complaints. Results. PSMU affects 8.9% adolescents in Italy and the prevalence is quite consistent across regions. 13-year-olds girls showed the highest percentage of PSMU (13%). Problematic users of social media are more likely to report multiple somatic (OR = 1.84 [95% CI 1.82-1.85]) and psychological (OR = 2.60 [95% CI 2.58-2.63]) symptoms. Conclusions. PSMU represents a widespread problem in Italy. National prevention interventions are needed in order to promote a positive use of social media.
Published: 2020

3. Dietary habits among Italian adolescents and their relation to socio-demographic characteristics

Author: Nardone, P, Pierannunzio, D, Ciardullo, S, Lazzeri, G, Cappello, N, Spinelli, A, Donati, S, Pizzi, E, Andreozzi, S, Bucciarelli, M, de Mei, B, Cattaneo, C, Cavallo, F, Piraccini, G, Berchialla, P, Borraccino, A, Charrier, L, Dalmasso, P, Lemma, P, Sciannameo, V, Vieno, A, Canale, N, Gaboardi, M, Lenzi, M, Marino, C, Santinello, M, Giacchi, M, Pammolli, A, Simi, R, Galeone, D, Menzano, M, Vienna, A, Colleluori, C, Di Giacomo, M, Ranalli, E, Cauzillo, G, Mininni, M, Sorrentino, G, Azzarito, C, Cernuzio, A, la Rocca, M, Pugliese, A, Mazzarella, G, Angelini, P, Fridel, M, Carletti, C, Concina, F, Ronfani, L, Pani, P, Cairella, G, Bosca, L, Pancallo, M, Ferrando, G, Celata, C, Coppola, L, Lobascio, C, Gelmi, G, Crottogini, L, Velasco, V, de Introna, S, Giostra, G, Ciallella, M, Colitti, M, Paolitto, E, Caputo, M, Stingi, D, Pacella, P, Pasquale, P, Palmas, M, Murgia, A, Cernigliaro, A, Ferro, M, Scondotto, S, Aramini, L, Corridori, V, Cristofori, M, Sorbelli, D, Giovannini, G, Covarino, A, Michieletto, F, Bino, E, Zuccali, M, Fanolla, A, Weiss, S, Nardone P., Pierannunzio D., Ciardullo S., Lazzeri G., Cappello N., Spinelli A., Donati S., Pizzi E., Andreozzi S., Bucciarelli M., de Mei B., Cattaneo C., Cavallo F., Piraccini G., Berchialla P., Borraccino A., Charrier L., Dalmasso P., Lemma P., Sciannameo V., Vieno A., Canale N., Gaboardi M., Lenzi M., Marino C., Santinello M., Giacchi M. V., Pammolli A., Simi R., Galeone D., Menzano M. T., Vienna A., Colleluori C., Di Giacomo M., Ranalli E., Cauzillo G., Mininni M., Sorrentino G., Azzarito C., Cernuzio A., la Rocca M., Pugliese A., Mazzarella G., Angelini P., Fridel M., Carletti C., Concina F., Ronfani L., Pani P., Cairella G., Bosca L., Pancallo M. T., Ferrando G., Celata C., Coppola L., Lobascio C., Gelmi G., Crottogini L., Velasco V., de Introna S., Giostra G., Ciallella M. L., Colitti M., Paolitto E., Caputo M., Stingi D., Pacella P., Pasquale P., Palmas M. A., Murgia A., Cernigliaro A., Ferro M. P., Scondotto S., Aramini L., Corridori V., Cristofori M., Sorbelli D., Giovannini G., Covarino A. M., Michieletto F., Bino E., Zuccali M. G., Fanolla A., Weiss S., Nardone, P, Pierannunzio, D, Ciardullo, S, Lazzeri, G, Cappello, N, Spinelli, A, Donati, S, Pizzi, E, Andreozzi, S, Bucciarelli, M, de Mei, B, Cattaneo, C, Cavallo, F, Piraccini, G, Berchialla, P, Borraccino, A, Charrier, L, Dalmasso, P, Lemma, P, Sciannameo, V, Vieno, A, Canale, N, Gaboardi, M, Lenzi, M, Marino, C, Santinello, M, Giacchi, M, Pammolli, A, Simi, R, Galeone, D, Menzano, M, Vienna, A, Colleluori, C, Di Giacomo, M, Ranalli, E, Cauzillo, G, Mininni, M, Sorrentino, G, Azzarito, C, Cernuzio, A, la Rocca, M, Pugliese, A, Mazzarella, G, Angelini, P, Fridel, M, Carletti, C, Concina, F, Ronfani, L, Pani, P, Cairella, G, Bosca, L, Pancallo, M, Ferrando, G, Celata, C, Coppola, L, Lobascio, C, Gelmi, G, Crottogini, L, Velasco, V, de Introna, S, Giostra, G, Ciallella, M, Colitti, M, Paolitto, E, Caputo, M, Stingi, D, Pacella, P, Pasquale, P, Palmas, M, Murgia, A, Cernigliaro, A, Ferro, M, Scondotto, S, Aramini, L, Corridori, V, Cristofori, M, Sorbelli, D, Giovannini, G, Covarino, A, Michieletto, F, Bino, E, Zuccali, M, Fanolla, A, Weiss, S, Nardone P., Pierannunzio D., Ciardullo S., Lazzeri G., Cappello N., Spinelli A., Donati S., Pizzi E., Andreozzi S., Bucciarelli M., de Mei B., Cattaneo C., Cavallo F., Piraccini G., Berchialla P., Borraccino A., Charrier L., Dalmasso P., Lemma P., Sciannameo V., Vieno A., Canale N., Gaboardi M., Lenzi M., Marino C., Santinello M., Giacchi M. V., Pammolli A., Simi R., Galeone D., Menzano M. T., Vienna A., Colleluori C., Di Giacomo M., Ranalli E., Cauzillo G., Mininni M., Sorrentino G., Azzarito C., Cernuzio A., la Rocca M., Pugliese A., Mazzarella G., Angelini P., Fridel M., Carletti C., Concina F., Ronfani L., Pani P., Cairella G., Bosca L., Pancallo M. T., Ferrando G., Celata C., Coppola L., Lobascio C., Gelmi G., Crottogini L., Velasco V., de Introna S., Giostra G., Ciallella M. L., Colitti M., Paolitto E., Caputo M., Stingi D., Pacella P., Pasquale P., Palmas M. A., Murgia A., Cernigliaro A., Ferro M. P., Scondotto S., Aramini L., Corridori V., Cristofori M., Sorbelli D., Giovannini G., Covarino A. M., Michieletto F., Bino E., Zuccali M. G., Fanolla A., and Weiss S.
Abstract: Objective. The aim is to describe dietary habits and their association with socio-demographic characteristics in a large nationally representative sample of Italian adolescents aged 11, 13 and 15 years. Materials and methods. Data from the 2018 Italian Health Behaviour in School-aged Children (HBSC) survey on 58,976 adolescents were analysed to determine eating habits. Logistic regression was used to investigate the association between incorrect dietary habits and potential predictors. Results. 38.3% of boys and 48.1% of girls skipped breakfast and 54.1% did not consume fruit and/or vegetables daily. 15.9% of boys and 11.3% of girls drank carbonated-sugary beverages at least once a day. Incorrect dietary habits were more common among boys, adolescents with lower socio-economic conditions, residents in Southern Italy and those spending more time watching TV. Italian adolescents were more likely to have incorrect dietary habits compared with those from most other countries involved in 2018 HBSC. Conclusions. Action is needed to improve dietary habits among adolescents.
Published: 2020

4. Problematic social media use: Associations with health complaints among adolescents

Author: Marino, C., Lenzi, M., Canale, N., Pierannunzio, D., Dalmasso, P., Borraccino, A., Cappello, N., Lemma, P., Vieno, A., Nardone, P., Spinelli, A., Donati, S., Pizzi, E., Ciardullo, S., Andreozzi, S., Bucciarelli, M., de Mei, B., Cattaneo, C., Cavallo, F., Piraccini, G., Berchialla, P., Charrier, L., Sciannameo, V., Gaboardi, M., Santinello, M., Lazzeri, G., Giacchi, M. V., Pammolli, A., Simi, R., Galeone, D., Menzano, M. T., Vienna, A., Colleluori, C., Di Giacomo, M., Ranalli, E., Cauzillo, G., Mininni, M., Sorrentino, G., Azzarito, C., Cernuzio, A., la Rocca, M., Pugliese, A., Mazzarella, G., Angelini, P., Fridel, M., Carletti, C., Concina, F., Ronfani, L., Pani, P., Cairella, G., Bosca, L., Pancallo, M. T., Ferrando, G., Celata, C., Coppola, L., Lobascio, C., Gelmi, G., Crottogini, L., Velasco, V., de Introna, S., Giostra, G., Ciallella, M. L., Colitti, M., Paolitto, E., Caputo, M., Stingi, D., Pacella, P., Pasquale, P., Palmas, M. A., Murgia, A., Cernigliaro, A., Ferro, M. P., Scondotto, S., Aramini, L., Corridori, V., Cristofori, M., Sorbelli, D., Giovannini, G., Covarino, A. M., Michieletto, F., Bino, E., Zuccali, M. G., Fanolla, A., Weiss, S., Marino, C, Lenzi, M, Canale, N, Pierannunzio, D, Dalmasso, P, Borraccino, A, Cappello, N, Lemma, P, Vieno, A, Nardone, P, Spinelli, A, Donati, S, Pizzi, E, Ciardullo, S, Andreozzi, S, Bucciarelli, M, de Mei, B, Cattaneo, C, Cavallo, F, Piraccini, G, Berchialla, P, Charrier, L, Sciannameo, V, Gaboardi, M, Santinello, M, Lazzeri, G, Giacchi, M, Pammolli, A, Simi, R, Galeone, D, Menzano, M, Vienna, A, Colleluori, C, Di Giacomo, M, Ranalli, E, Cauzillo, G, Mininni, M, Sorrentino, G, Azzarito, C, Cernuzio, A, la Rocca, M, Pugliese, A, Mazzarella, G, Angelini, P, Fridel, M, Carletti, C, Concina, F, Ronfani, L, Pani, P, Cairella, G, Bosca, L, Pancallo, M, Ferrando, G, Celata, C, Coppola, L, Lobascio, C, Gelmi, G, Crottogini, L, Velasco, V, de Introna, S, Giostra, G, Ciallella, M, Colitti, M, Paolitto, E, Caputo, M, Stingi, D, Pacella, P, Pasquale, P, Palmas, M, Murgia, A, Cernigliaro, A, Ferro, M, Scondotto, S, Aramini, L, Corridori, V, Cristofori, M, Sorbelli, D, Giovannini, G, Covarino, A, Michieletto, F, Bino, E, Zuccali, M, Fanolla, A, and Weiss, S
Subjects: Male, Adolescent, Problematic use, Psychosomatic symptom, Adolescence, Social media, Cross-Sectional Studies, Italy, Psychosomatic symptoms, Child, Female, Humans, Internet Addiction Disorder, Prevalence, Self Report, Social Media
Abstract: Objective. Problematic Social Media Use (PSMU) has an addictive potential for young users. The aim of this study was to show the prevalence of PSMU across Italian regions and its association with health complaints. Materials and methods. Data are gathered from the Italian 2018 Health Behaviour in School-aged Children survey using a representative sample of Italian adolescents aged 11, 13 and 15 years (50.6% males). Participants completed self-administered questionnaires assessing PSMU and health complaints. Results. PSMU affects 8.9% adolescents in Italy and the prevalence is quite consistent across regions. 13-year-olds girls showed the highest percentage of PSMU (13%). Problematic users of social media are more likely to report multiple somatic (OR = 1.84 [95% CI 1.82-1.85]) and psychological (OR = 2.60 [95% CI 2.58-2.63]) symptoms. Conclusions. PSMU represents a widespread problem in Italy. National prevention interventions are needed in order to promote a positive use of social media.
Published: 2020

5. Dietary habits among Italian adolescents and their relation to socio-demographic characteristics

Author: Nardone P., Pierannunzio D., Ciardullo S., Lazzeri G., Cappello N., Spinelli A., Donati S., Pizzi E., Andreozzi S., Bucciarelli M., de Mei B., Cattaneo C., Cavallo F., Piraccini G., Berchialla P., Borraccino A., Charrier L., Dalmasso P., Lemma P., Sciannameo V., Vieno A., Canale N., Gaboardi M., Lenzi M., Marino C., Santinello M., Giacchi M. V., Pammolli A., Simi R., Galeone D., Menzano M. T., Vienna A., Colleluori C., Di Giacomo M., Ranalli E., Cauzillo G., Mininni M., Sorrentino G., Azzarito C., Cernuzio A., la Rocca M., Pugliese A., Mazzarella G., Angelini P., Fridel M., Carletti C., Concina F., Ronfani L., Pani P., Cairella G., Bosca L., Pancallo M. T., Ferrando G., Celata C., Coppola L., Lobascio C., Gelmi G., Crottogini L., Velasco V., de Introna S., Giostra G., Ciallella M. L., Colitti M., Paolitto E., Caputo M., Stingi D., Pacella P., Pasquale P., Palmas M. A., Murgia A., Cernigliaro A., Ferro M. P., Scondotto S., Aramini L., Corridori V., Cristofori M., Sorbelli D., Giovannini G., Covarino A. M., Michieletto F., Bino E., Zuccali M. G., Fanolla A., Weiss S., Nardone, P, Pierannunzio, D, Ciardullo, S, Lazzeri, G, Cappello, N, Spinelli, A, Donati, S, Pizzi, E, Andreozzi, S, Bucciarelli, M, de Mei, B, Cattaneo, C, Cavallo, F, Piraccini, G, Berchialla, P, Borraccino, A, Charrier, L, Dalmasso, P, Lemma, P, Sciannameo, V, Vieno, A, Canale, N, Gaboardi, M, Lenzi, M, Marino, C, Santinello, M, Giacchi, M, Pammolli, A, Simi, R, Galeone, D, Menzano, M, Vienna, A, Colleluori, C, Di Giacomo, M, Ranalli, E, Cauzillo, G, Mininni, M, Sorrentino, G, Azzarito, C, Cernuzio, A, la Rocca, M, Pugliese, A, Mazzarella, G, Angelini, P, Fridel, M, Carletti, C, Concina, F, Ronfani, L, Pani, P, Cairella, G, Bosca, L, Pancallo, M, Ferrando, G, Celata, C, Coppola, L, Lobascio, C, Gelmi, G, Crottogini, L, Velasco, V, de Introna, S, Giostra, G, Ciallella, M, Colitti, M, Paolitto, E, Caputo, M, Stingi, D, Pacella, P, Pasquale, P, Palmas, M, Murgia, A, Cernigliaro, A, Ferro, M, Scondotto, S, Aramini, L, Corridori, V, Cristofori, M, Sorbelli, D, Giovannini, G, Covarino, A, Michieletto, F, Bino, E, Zuccali, M, Fanolla, A, and Weiss, S
Subjects: Male, vegetables, eating behaviour, Adolescent, breakfast, Feeding Behavior, fruit, Cross-Sectional Studies, beverage, Italy, Socioeconomic Factors, Humans, Female, Child, Demography
Abstract: Objective. The aim is to describe dietary habits and their association with socio-demographic characteristics in a large nationally representative sample of Italian adolescents aged 11, 13 and 15 years. Materials and methods. Data from the 2018 Italian Health Behaviour in School-aged Children (HBSC) survey on 58,976 adolescents were analysed to determine eating habits. Logistic regression was used to investigate the association between incorrect dietary habits and potential predictors. Results. 38.3% of boys and 48.1% of girls skipped breakfast and 54.1% did not consume fruit and/or vegetables daily. 15.9% of boys and 11.3% of girls drank carbonated-sugary beverages at least once a day. Incorrect dietary habits were more common among boys, adolescents with lower socio-economic conditions, residents in Southern Italy and those spending more time watching TV. Italian adolescents were more likely to have incorrect dietary habits compared with those from most other countries involved in 2018 HBSC. Conclusions. Action is needed to improve dietary habits among adolescents.
Published: 2020

6. [SENTIERI - Epidemiological study of residents in national priority contaminated sites: incidence of mesothelioma]

Author: Binazzi, A, Bruno, C, Comba, P, Conti, S, Corfiati, M, Fazzo, L, Manno, V, Marinaccio, A, Menegozzo, S, Minelli, G, Pasetto, R, Pirastu, R, Zona, A, ANGELILLO, Italo Francesco, Canessa, Pa, Cauzillo, G, Cavone, D, Chellini, E, Cocchioni, M, De Michieli, P, Forastiere, F, Davoli, M, Di Giammarco, A, Gennaro, V, Giaimo, M, Gioffrè, F, Mangone, L, Mazzoleni, G, Mensi, C, Merler, E, Merletti, F, Merseburger, A, Miligi, L, Mirabelli, D, Musti, M, Negro, C, Nicita, C, Pascucci, C, Riboldi, L, Romanelli, A, Schallemberg, G, Stracci, F, Trafficante, L, Tumino, R., Binazzi, A, Bruno, C, Comba, P, Conti, S, Corfiati, M, Fazzo, L, Manno, V, Marinaccio, A, Menegozzo, S, Minelli, G, Pasetto, R, Pirastu, R, Zona, A, Angelillo, Italo Francesco, Canessa, Pa, Cauzillo, G, Cavone, D, Chellini, E, Cocchioni, M, De Michieli, P, Forastiere, F, Davoli, M, Di Giammarco, A, Gennaro, V, Giaimo, M, Gioffrè, F, Mangone, L, Mazzoleni, G, Mensi, C, Merler, E, Merletti, F, Merseburger, A, Miligi, L, Mirabelli, D, Musti, M, Negro, C, Nicita, C, Pascucci, C, Riboldi, L, Romanelli, A, Schallemberg, G, Stracci, F, Trafficante, L, and Tumino, R.
Abstract: The purpose of SENTIERI-ReNaM Project is to describe mesothelioma incidence in the Italian National Priority Contaminated Sites (NPCSs). The present report deals with 39 NPCSs (20 in Northern Italy, 8 in Central Italy and 11 in Southern Italy). Asbestos is specifically mentioned in the regulatory acts of recognition for 10 NPCSs and it is the only agent that has determined environmental contamination in 3 of them (Casale Monferrato, Broni, and Bari). The timeframe of the study is 2000-2011 for 34 out of 39 sites. The corresponding reference periods for the sites of Latium, Campania, Umbria, and Bolzano Province are, respectively, 2001-2011, 2005-2011, and 2006-2011. Standardized Incidence Ratios (SIRs) for mesothelioma, with their corresponding 90% Confidence Intervals, have been estimated for all sites. The interpretation of the study findings has been based on anamnestic information made available by the Italian National Mesothelioma Registry (ReNaM), and completed thanks to knowledge derived from the international scientific literature. In men, mesothelioma incidence has shown excesses in 27/39 sites and defects in the remaining 12; in women, excesses have been reported in 20 sites, defects in 15, and no cases have been detected in the remaining 4 sites. The highest annual incidence rates have been observed in the sites characterized only by the presence of asbestos- cement factories (Broni and Casale Monferrato): respectively, 98.0 and 68.6 per 100,000 per year in men, 72.1 and 45.8 in women. Besides these two sites, the highest rates have been observed in the sites with naval shipyards: 13.2 in men and 2.5 in women. Excesses of mesothelioma incidence have been confirmed (with respect to previous observations) in the sites of Broni, Casale Monferrato, Balangero, and in the coastal areas of Trieste, La Spezia, Venice, and Leghorn. Balangero has been the major European chrysotile quarry, while the other sites are characterized by the presence of naval shipyards with demonstrated use of asbestos before it was banned in 1992. An excess of mesothelioma incidence has also been confirmed in the site of Biancavilla, characterized by the presence of the fluoro-edenite fibrous amphibole, classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC). An increased incidence of mesothelioma was also observed in the areas where no direct use of asbestos had previously been documented, like Cengio and Saliceto (chemical industry), Falconara on Sea (oil refinery), and Litorale Domizio Flegreo and Agro Aversano (a large area including multiple hazardous waste dumping sites). These findings show that a relevant proportion of Italian mesothelioma cases is concentrated in NPCSs. About 1,500 extra cases of mesothelioma have been estimated in the overall series of 39 sites (2000-2011), corresponding to 125 extra cases per year. The excess has concerned the sites with manufacture of asbestos-cement products, but also the areas with asbestos quarries, naval shipyards, illegal hazardous waste dumping sites with asbestos-containing materials, petrochemical industries, refineries and steel plants. In some sites, particularly Casale Monferrato and Broni, analytical epidemiological studies have shown the causal role of not only occupational, but also environmental exposures, with special reference to paving of gardens and courtyards with asbestos-cement industry by-products. The main novelty generated by the collaborative SENTIERI-ReNaM Project concerns the detection of significant mesothelioma excesses not only in sites where asbestos is explicitly reported as a source of contamination, but also in a number of areas defined "of national interest" for environmental cleanup due to other sources of pollution. This confirms that the range of economic activities and working and living environments affected by asbestos exposure is very wide and it is not restricted to the industrial sectors characterized by the direct use of this material.
Published: 2016

7. SENTIERI-ReNaM: Valutazione globale del carico di mesotelioma

Author: Binazzi A, GdL SENTIERI-ReNaM., Bruno, C, Comba, PAOLO GIOVANNI, Conti, S, Corfiati, M, Fazzo, L, Manno, V, Marinaccio, A, Menegozzo, S, Minelli, Giuditta, Pasetto, R, Pirastu, R, Zona, A, Angelillo, I, Canessa, Pa, Cauzillo, G, Cavone, D, Chellini, E, Cocchioni, M, De Michieli, P, Forastiere, F, Davoli, M, Di Giammarco, A, Gennaro, V, Giaimo, M, Gioffrè, F, Mangone, L, Mazzoleni, G, Mensi, C, Merler, E, Merletti, F, Merseburger, A, Miligi, L, Mirabelli, D, Musti, M, Negro, C, Nicita, C, Pascucci, C, Riboldi, Lorenzo, Romanelli, A, Schallemberg, G, Stracci, F, Trafficante, Luigi Alberto, and Tumino, R.
Subjects: Mesothelioma, Male, Risk, Epidemiology, Incidence, Asbestos, Burden of illness, Italy, National Priority Contaminated Sites - NPCSs, Carcinogens, Environmental, Confidence Intervals, Female, Health Surveys, Humans, Industry, Occupational Exposure, Registries, Environmental Exposure, Environmental Pollution, Hazardous Waste Sites, Public Health, Environmental and Occupational Health, Environmental and Occupational Health, Environmental, Carcinogens, Public Health
Published: 2017

8. [SENTIERI-ReNaM: Discussion and concluding remarks]

Author: Zona, Amerigo, Fazzo, Lucia, Binazzi, Alessandra, Bruno, Caterina, Corfiati, Marisa, Comba, Pietro, Conti, Susanna, Menegozzo, Simona, Nicita, Carmela, Pasetto, Roberto, Pirastu, Roberta, Marinaccio, Alessandro, Binazzi A, GdL SENTIERI-ReNaM., Bruno, C, Comba, P, Conti, S, Corfiati, M, Fazzo, L, Manno, V, Marinaccio, A, Menegozzo, S, Minelli, G, Pasetto, R, Pirastu, R, Zona, A, Angelillo, I, Canessa, Pa, Cauzillo, G, Cavone, D, Chellini, E, Cocchioni, M, De Michieli, P, Forastiere, F, Davoli, M, Di Giammarco, A, Gennaro, V, Giaimo, M, Gioffrè, F, Mangone, L, Mazzoleni, G, Mensi, C, Merler, E, Merletti, F, Merseburger, A, Miligi, L, Mirabelli, D, Musti, M, Negro, C, Nicita, C, Pascucci, C, Riboldi, L, Romanelli, A, Schallemberg, G, Stracci, F, Trafficante, L, and Tumino, R.
Subjects: Male, Mesothelioma, Risk, Incidence, Asbestos, Environmental Exposure, Health Surveys, Carcinogens, Environmental, Environmental, Italy, Occupational Exposure, Hazardous Waste Sites, Carcinogens, Confidence Intervals, Humans, Industry, Female, Registries, Environmental Pollution
Abstract: SENTIERI-ReNaM Project analysed the incidence of malignant mesothelioma (MM) for the period 2000-2011 in 39 National Priority Contaminated Sites (NPCSs), and assessed the overall impact of mesothelioma in different types of NPCSs. In the study period, 2,683 incident cases of malignant mesothelioma were recorded: 1,998 males (74.5%), 685 females (25.5%). Excluding cases with non attributable exposure and those non interviewed, exposure was identified in 1,926 cases (70% of all cases): 1,541 males (occupational exposure: 1,414; environmental exposure: 82), 385 females (occupational exposure: 103; environmental exposure: 141). Women experienced mainly environmental and domestic exposures to asbestos. Standard Incidence Ratio (SIR) excesses were observed in men in 27 out of 39 NPCSs and defects in the remaining 12; in women, 20 NPCSs showed SIR excesses, defects in 15; in 4 NPCSs no MM cases occurred among female population. The highest rates were found in NPCSs with asbestos-cement plants (Broni and Casale Monferrato), respectively, 98 per 100,000 per year and 68.6 in men, 72.1 and 45.8 in women. Excluding these two sites, the highest incidence rates were found in the group with harbours and shipyards, where the rates were, respectively, 13.2 among men and 2.5 among women. The results of this report will be communicated to national and local institutions, as well as to NPCSs resident populations.
Published: 2016

9. [SENTIERI-ReNaM: Results]

Author: Binazzi, Alessandra, Zona, Amerigo, Marinaccio, Alessandro, Bruno, Caterina, Corfiati, Marisa, Fazzo, Lucia, Menegozzo, Simona, Nicita, Carmela, Pasetto, Roberto, Pirastu, Roberta, De Santisi, Marco, Comba, Pietro, Binazzi A, GdL SENTIERI-ReNaM., Bruno, C, Comba, PAOLO GIOVANNI, Conti, S, Corfiati, M, Fazzo, L, Manno, V, Marinaccio, A, Menegozzo, S, Minelli, G, Pasetto, R, Pirastu, R, Zona, A, Angelillo, I, Canessa, Pa, Cauzillo, G, Cavone, D, Chellini, E, Cocchioni, M, De Michieli, P, Forastiere, F, Davoli, M, Di Giammarco, A, Gennaro, V, Giaimo, M, Gioffrè, F, Mangone, L, Mazzoleni, G, Mensi, C, Merler, E, Merletti, F, Merseburger, A, Miligi, L, Mirabelli, D, Musti, M16, 17 Negro, C, Nicita, C, Pascucci, C, Riboldi, L, Romanelli, A, Schallemberg, G, Stracci, F, Trafficante, L, and Tumino, R.
Subjects: Male, Mesothelioma, Risk, Incidence, Asbestos, Environmental Exposure, Health Surveys, Carcinogens, Environmental, Environmental, Italy, Occupational Exposure, Hazardous Waste Sites, Carcinogens, Confidence Intervals, Humans, Industry, Female, Registries, Environmental Pollution
Abstract: Mesothelioma incidence has been analyzed in National Priority Contaminated Sites (NPCSs) to estimate the health impact of asbestos exposure on resident people. The burden of professional and environmental exposures has been identified through data of the Regional Operational Centres (CORs), made available by the Italian National Mesothelioma Registry (ReNaM). An excess of mesothelioma incidence is confirmed in sites with a known past history of direct use of asbestos, such as Balangero, Casale Monferrato, Broni, Bari-Fibronit, and in coastal areas, where shipyards, harbours and other industries that involved a wide use of asbestos are represented (e.g., Trieste, La Spezia, Venice, and Leghorn). An excess of mesothelioma has been observed in settings where the asbestos is not mentioned as contaminant in the decree that included these sites among NPCSs, such as Cengio and Saliceto in Northern Italy; Falconara Marittima and the Bacino Idrografico Fiume Sacco in the Central Italy; the Litorale Domizio Flegreo and Agro Aversano, Milazzo, and Gela in the Southern Italy. Observed excess in the various NPCSs confirms the large-scale occurrence in contaminated Italian sites of a significant amount of total mesothelioma cases observed at national level. The analysis of occupational risk in epidemiological studies with an ecological design helps in defining the contribution of different factors to the overall risk.
Published: 2016

10. Progress in infection prevention and control in Italy: a nationwide survey

Author: Moro, Ml, Marchi, M, Buttazzi, R, Nascetti, S, Collaborators: Pompa MG, INF OSS Project G. r. o. u. p., Salcuni, P, Scassa, E, Scudieri, M, Cauzillo, G, Locuratolo, F, Barone, R, Pizzuti, R, Sarnelli, B, Simon, G, Turello, D, Trevisan, R, Puro, V, Martini, L, Mandolini, D, Vizio, M, Nannini, M, Pavan, A, Bernieri, F, D'Errico, M, Prospero, E, Zotti, Carla Maria, Dipietrantonj, C, Prato, R, Villone, G, Balducci, Mt, Mura, M, Mura, I, Maniaci, L, Cantaro, Sp, Poli, A, Privitera, G, Porretta, A, Fiorio, M, Montedori, A, Sacco, R, Mastaglia, M, Spolaore, P, Fedeli, U, Santa, Pj, Fabbri, L, and Piccini, G.
Subjects: Microbiology (medical), Pediatrics, medicine.medical_specialty, Community service, Nationwide survey, prevention, medicine, Humans, Infection control, survey, Clinical risk management, Healthcare related Infection, Response rate (survey), Cross Infection, Infection Control, business.industry, Public health, Health services research, General Medicine, Infectious Diseases, Italy, Respondent, Health Services Research, business, Demography
Abstract: A national survey was conducted to describe the coverage and characteristics of infection prevention and control (IC) programmes in Italy and to evaluate progress during recent years. All regions, with one small exception, participated and the response rate was 88%. Nearly all 278 respondent public health trusts reported having an IC committee, 80% of the 615 respondent hospitals to have instituted an IC team, and 79% to have an IC nurse. However, when the presence of truly operating IC bodies was considered, the pattern was different: only 27% of IC teams met at least monthly, and variation by region was extremely large [coefficient of variation (CV): 1.06]. The IC programme characteristics with the greatest variation by region included: availability of qualified nurses and IC doctors (CV: 1.55 and 1.39 respectively); integration of IC activities and clinical risk management (CV: 1.05); IC programmes also involving community services (CV: 0.98); training of personnel at induction (CV: 0.82); and availability of written policies for the control of multidrug-resistant organisms (CV: 1.08). A relevant and statistically significant North-South gradient showed Southern Regions averaging 23 points less than Northern Regions on the IC score. Compared with a similar survey conducted in 2000, the distribution of several activities by region had improved significantly. Despite the noteworthy improvement observed over time, the situation in Italy is still unsatisfactory, due to significant variation in the development of IC organisations and initiatives by region and by type of hospital.
Published: 2011

11. The methodology of the Italian HBSC 2010 study (Health Behaviour in School-aged Children)

Author: Lazzeri, G, Giacchi, M, Dalmasso, P, Vieno, A, Nardone, P, Lamberti, A, Spinelli, A, Cavallo, F, Lemma, P, Berchialla, P, Colombini, S, Zambon, A, Charrier, L, Borraccino, A, Pilato, V, Rossi, S, Pammolli, A, Santinello, M, Chieco, F, Lenzi, M, Baglio, G, Galeone, D, Spizzichino, L, Menzano, M, Scotti, M, Silani, M, Teti, S, Ciglia, A, Di Giacomo, M, Spinosa, S, Ammirati, G, Cauzillo, G, Sorrentino, G, Azzarito, C, La Rocca, M, Pizzuti, R, Mazzarella, G, Di Martino, E, Angelini, P, Fridel, M, Bavcar, A, Castronuovo, G, Pascali, F, Celata, C, Tosi, M, Velasco, V, Bonfanti, M, Coppola, L, Giostra, G, Ciallella, M, Caputo, M, Viesti, E, Rosa, G, Anelli, S, Meloni, S, Senis, M, Masala, R, Cernigliaro, A, Rizzo, S, Giannoni, A, Cristofori, M, Covarino, A, D'Alessandro, G, Piffer, S, Fanolla, A, Weiss, S, Lazzeri G., Giacchi M. V., Dalmasso P., Vieno A., Nardone P., Lamberti A., Spinelli A., Cavallo F., Lemma P., Berchialla P., Colombini S., Zambon A., Charrier L., Borraccino A., Pilato V., Rossi S., Pammolli A., Santinello M., Chieco F., Lenzi M., Baglio G., Galeone D., Spizzichino L., Menzano M. T., Scotti M. T., Silani M. T., Teti S., Ciglia A., Di Giacomo M., Spinosa S., Ammirati G., Cauzillo G., Sorrentino G., Azzarito C., La Rocca M., Pizzuti R., Mazzarella G., Di Martino E., Angelini P., Fridel M., Bavcar A., Castronuovo G. C. E., Pascali F., Celata C., Tosi M., Velasco V., Bonfanti M., Coppola L., Giostra G., Ciallella M. L., Caputo M., Viesti E., Rosa G., Anelli S., Meloni S., Senis M. L., Masala R., Cernigliaro A., Rizzo S., Giannoni A. M., Cristofori M., Covarino A. M., D'alessandro G., Piffer S., Fanolla A., Weiss S., Lazzeri, G, Giacchi, M, Dalmasso, P, Vieno, A, Nardone, P, Lamberti, A, Spinelli, A, Cavallo, F, Lemma, P, Berchialla, P, Colombini, S, Zambon, A, Charrier, L, Borraccino, A, Pilato, V, Rossi, S, Pammolli, A, Santinello, M, Chieco, F, Lenzi, M, Baglio, G, Galeone, D, Spizzichino, L, Menzano, M, Scotti, M, Silani, M, Teti, S, Ciglia, A, Di Giacomo, M, Spinosa, S, Ammirati, G, Cauzillo, G, Sorrentino, G, Azzarito, C, La Rocca, M, Pizzuti, R, Mazzarella, G, Di Martino, E, Angelini, P, Fridel, M, Bavcar, A, Castronuovo, G, Pascali, F, Celata, C, Tosi, M, Velasco, V, Bonfanti, M, Coppola, L, Giostra, G, Ciallella, M, Caputo, M, Viesti, E, Rosa, G, Anelli, S, Meloni, S, Senis, M, Masala, R, Cernigliaro, A, Rizzo, S, Giannoni, A, Cristofori, M, Covarino, A, D'Alessandro, G, Piffer, S, Fanolla, A, Weiss, S, Lazzeri G., Giacchi M. V., Dalmasso P., Vieno A., Nardone P., Lamberti A., Spinelli A., Cavallo F., Lemma P., Berchialla P., Colombini S., Zambon A., Charrier L., Borraccino A., Pilato V., Rossi S., Pammolli A., Santinello M., Chieco F., Lenzi M., Baglio G., Galeone D., Spizzichino L., Menzano M. T., Scotti M. T., Silani M. T., Teti S., Ciglia A., Di Giacomo M., Spinosa S., Ammirati G., Cauzillo G., Sorrentino G., Azzarito C., La Rocca M., Pizzuti R., Mazzarella G., Di Martino E., Angelini P., Fridel M., Bavcar A., Castronuovo G. C. E., Pascali F., Celata C., Tosi M., Velasco V., Bonfanti M., Coppola L., Giostra G., Ciallella M. L., Caputo M., Viesti E., Rosa G., Anelli S., Meloni S., Senis M. L., Masala R., Cernigliaro A., Rizzo S., Giannoni A. M., Cristofori M., Covarino A. M., D'alessandro G., Piffer S., Fanolla A., and Weiss S.
Abstract: Italy has participated in the Health Behaviour in School-aged Children (HBSC) study since 2000. These surveys collect data every four years on the well-being and health behaviour of boys and girls aged 11, 13 and 15. Until 2007, the coordination group of the University of Turin, Siena and Padua directly sent the questionnaires to each sampled school to collect the data. The sample of about 4500 students was nationally representative. In 2008 the HBSC became part of the project "Surveys on behavioral risks in children aged 6-17 years", coordinated by the National Institute of Health (ISS) and promoted by the Ministry of Health, in collaboration with the Ministry of Education, University and Research. For the first time, in 2010, the survey was conducted by health workers in collaboration with teachers in all regions with a representative sample, not just at the national level, but also at regional level. In the 2,504 sampled schools, 77,113 students (25,079 eleven-year-old, 26,048 thirteen-year-old and 25,986 fifteen-year-old) completed an anonymous questionnaire. Knowledge of the health-related behaviour of school-aged adolescents may help monitoring and enable policies for young people to be formulated and implemented.
Published: 2013

12. [Epidemiologic surveillance of mesothelioma for the prevention of asbestos exposure also in non-traditional settings]

Author: Binazzi, A., Scarselli, A., Corfiati, M., Di Marzio, D., Branchi, C., Verardo, M., Mirabelli, D., Gennaro, V., Mensi, C., Schallenberg, G., Merler, E., De Zotti, R., Romanelli, A., Chellini, E., Pascucci, C., D'Alo, D., Forastiere, F., Trafficante, L., Menegozzo, S., Musti, M., Cauzillo, G., Leotta, A., Tumino, R., Melis, M., Marinaccio, A., Gruppo Di, Lavoro Renam Detragiache E., Merletti, F., Gangemi, M., Stura, A., Brentisci, C., Diglio, Cammarieri G., Macerata, V., Gilardetti, M., Benfatto, L., Bianchelli, M., Mazzucco, G., Sieno, C., Pesatori, A., Riboldi, L., Gioffre, F., Bressan, V., De Michieli, P., Chermaz, C., Negro, C., Mangone, L., Storchi, C., Silvestri, S., Badiali, A., Cacciarini, V., Giovannetti, L., Martini, A., Calisti, R., La Rosa, F., Stracci, F., Cavariani, F., Ascoli, Valeria, Romeo, E., Sangalli, M., Gatta, S., Izzo, F., Canfora, M., Santoro, M., Viscardi, F., Cavone, D., Massaro, T., Convertini, L., Giovanni, L., Nicita, C., Nieddu, V., Pergola, M., Stecchi, S., Dardanoni, G., and Scondotto, S.
Subjects: Male, Mesothelioma, Lung Neoplasms, asbestos, epidemiologic surveillance, prevention, mesothelioma, Pleural Neoplasms, Mesothelioma, Malignant, Asbestos, Middle Aged, Occupational Diseases, Italy, Occupational Exposure, Population Surveillance, Epidemiological Monitoring, Humans, Female, Registries
Abstract: To show how malignant mesothelioma (MM) surveillance not only identifies settings of exposure representing past industrial history, but it may also detect conditions of current exposure relevant for the prevention, if the wide spectrum of asbestos uses is considered.Active search of MM cases and exposure assessment at individual level through a questionnaire; identification of exposure circumstances relevant for prevention.Italy, all the Regions where a Regional Operating Centre (COR) is established to identify all MM cases diagnosed in the population and analyze their occupational, residential, household and environmental histories. Period of diagnosis: 1993-2008.Descriptive analysis of MM cases and of asbestos exposures.ReNaM includes 15,845 cases of MM diagnosed between 1993 and 2008.The male/female ratio is 2.5. Mean age at diagnosis is 69 years. Pleural MMs represent 93% of all cases. Exposures have been investigated in 12,065 cases (76%). The median latency time is 46 years. In addition to clusters of MM cases in activities well known to entail asbestos use, different current exposure circumstances requiring intervention have been evidenced.On the basis of this experience, epidemiological surveillance of all occupational cancers should be implemented to foster synergies with the compensation system and the Local Health Authorities' occupational safety and health services, as required by the Italian Legislative Decree N. 81/2008.
Published: 2013

13. Pleural malignant mesothelioma epidemic: incidence, modalities of asbestos exposure and occupations involved from the Italian National Register

Author: Marinaccio, A, Binazzi, A, Marzio, Dd, Scarselli, A, Verardo, M, Mirabelli, D, Gennaro, V, Mensi, C, Riboldi, L, Merler, E, Zotti, Rd, Romanelli, A, Chellini, E, Silvestri, S, Pascucci, C, Romeo, E, Menegozzo, S, Musti, M, Cavone, D, Cauzillo, G, Tumino, R, Nicita, C, Melis, M, Iavicoli, S, ReNaM Working Group, Massari, S, Branchi, C, Detragiache, E, Merletti, Franco, Gangemi, M, Stura, A, Brentisci, C, Cammarieri Diglio, G, Macerata, V, Gilardetti, M, Lazzarotto, A, Benfatto, L, Bianchelli, M, Mazzucco, G, Sieno, C, Pesatori, Ac, Gioffrè, F, Bressan, V, De Michieli, P, Mangone, L, Storchi, C, Seniori Costantini, A, Badiali, Am, Cacciarini, V, Giovannetti, L, Martini, A, Calisti, R, La Rosa, F, Stracci, F, D'Alò, D, Perucci, Ca, Forastiere, F, Cavariani, F, Ascoli, V, Sangalli, M, Trafficante, L, Gatta, S, Menegozzo, M, Izzo, F, Canfora, Ml, Santoro, M, Viscardi, F, Massaro, T, Convertini, L, Leotta, A, Lio, Sg, Dardanoni, G, Scondotto, S, Corrias, Ga, Angius, Mr, and Nieddu, V.
Subjects: Adult, Male, Mesothelioma, Cancer Research, medicine.medical_specialty, Pathology, Pleural Neoplasms, asbestos, italy, mesothelioma, national register, pleural, Developing country, medicine.disease_cause, Asbestos, Occupational safety and health, Environmental health, Occupational Exposure, Epidemiology, medicine, Humans, Epidemics, Pleural mesothelioma, Aged, business.industry, Incidence (epidemiology), Age Factors, Environmental exposure, Middle Aged, medicine.disease, Occupational Diseases, Oncology, Italy, Population Surveillance, Etiology, Female, business
Abstract: Due to the large scale use of asbestos (more than 3.5 million tons produced or imported until its definitive banning in 1992), a specific national surveillance system of mesothelioma incident cases is active in Italy, with direct and individual anamnestic etiological investigation. In the period between 1993 and 2004, a case-list of 8,868 pleural MM was recorded by the Italian National Register (ReNaM) and the modalities of exposure to asbestos fibres have been investigated for 6,603 of them. Standardized incidence rates are 3.49 (per 100,000 inhabitants) for men and 1.25 for women, with a wide regional variability. Occupational asbestos exposure was in 69.3% of interviewed subjects (N = 4,577 cases), while 4.4% was due to cohabitation with someone (generally, the husband) occupationally exposed, 4.7% by environmental exposure from living near a contamination source and 1.6% during a leisure activity. In the male group, 81.5% of interviewed subjects exhibit an occupational exposure. In the exposed workers, the median year of first exposure was 1957, and mean latency was 43.7 years. The analysis of exposures by industrial sector focuses on a decreasing trend for those traditionally signaled as "at risk" (asbestos-cement industry, shipbuilding and repair and railway carriages maintenance) and an increasing trend for the building construction sector. The systematic mesothelioma surveillance system is relevant for the prevention of the disease and for supporting an efficient compensation system. The existing experience on all-too-predictable asbestos effects should be transferred to developing countries where asbestos use is spreading.
Published: 2011

14. Il sistema di sorveglianza OKkio alla SALUTE: il ruolo della scuola primaria nella promozione di stili di vita salutari. Risultati 2008 [Surveillance system OKkio alla SALUTE: the role of primary school in the promotion of healthy life style. Results of 2008]

Author: Lamberti, A, Spinelli, A, Baglio, G, Nardone, P, Silani, Mt, Mastantuono, E, Teti, S, Menzano, Mt, Galeone, D, Gruppo OKkio alla SALUTE 2008, Andreozzi, S, Binkin, N, Bucciarelli, M, Meucci, S, Perra, A, Censi, L, D'Addesa, D, D'Amicis, A, Ciglia, A, Di Giacomo, M, Cauzillo, G, Sorrentino, G, Fersini, G, Perri, G, La Rocca, M, De Lorenzo, G, Angelini, P, Di Martino, E, Carletti, C, Rincorosi, R, Cairella, G, Castronuovo, E, Pascali, F, Oreste, P, Giostra, G, Tagliavento, G, Selvaggi, Tm, Caputo, M, Anelli, S, Pomo, V, Arras, P, Cattina, G, Cernigliaro, A, Rizzo, S, Giacchi, M, Lazzeri, G, Cristofori, M, Giaimo, M, Covarino, Am, D'Alessandro, G, Galesso, R, Tamang, Me, and Piffer, S.
Published: 2010

15. Il Progetto Salute e Ambiente della Val d'Agri (Basilicata): metodologia e risultati preliminari

Author: Federico, Bruno, Giordano, E, Mainelli, Maria Teresa, Galasso, R, Cauzillo, G, Santangelo, A, Cosentino, M, Damiani, Gianfranco, and Medici Di Medicina Generale, Del Progetto Salute E. Ambiente
Subjects: preliminari, Settore MED/42 - IGIENE GENERALE E APPLICATA
Published: 2010

16. Strategies for cardiovascular prevention in children [Strategie differenziate nelle popolazioni target: I bambini]

Author: Spinelli, A, Nardone, P, Lamberti, A, Baglio, G, Gruppo OKkio alla SALUTE 2008, Andreozzi, S, Binkin, N, Bucciarelli, M, Cattaneo, C, Fontana, G, Meucci, S, Perra, A, Galeone, D, Silani, Mt, Mastantuono, E, Teti, S, Censi, L, D'Addesa, D, D'Amicis, A, Ciglia, A, Di Giacomo, M, Cauzillo, G, Sorrentino, G, Fersini, G, La Rocca, M, Perri, G, De Lorenzo, G, Angelini, P, Di Martino, E, Carletti, C, Rincorosi, R, Cairella, G, Castronuovo, E, Pascali, F, Oreste, P, Giostra, G, Tagliavento, G, Selvaggi, Tm, Caputo, M, Anelli, S, Pomo, V, Arras, P, Cattina, G, Cernigliaro, A, Rizzo, S, Giacchi, MARIANO VINCENZO, Lazzeri, Giacomo, Cristofori, M, Giaimo, M, Covarino, Am, D'Alessandro, G, Riccardo, G, Tamang, Me, Piffer, S, Baldi, A, Balducci, Mt, Bilei, S, Callipari, O, De Luca, A, Di Fabio, M, Marrone, A, Mazzarella, G, Silvestri, A, Caroli, M, Cavallo, F, Silvestri, Ar, Spenelli, A, and Spizzichino, L.
Published: 2010

17. Incidence of extrapleural malignant mesothelioma and asbestos exposure, from the Italian national register

Author: Marinaccio, A., primary, Binazzi, A., additional, Di Marzio, D., additional, Scarselli, A., additional, Verardo, M., additional, Mirabelli, D., additional, Gennaro, V., additional, Mensi, C., additional, Merler, E., additional, De Zotti, R., additional, Mangone, L., additional, Chellini, E., additional, Pascucci, C., additional, Ascoli, V., additional, Menegozzo, S., additional, Cavone, D., additional, Cauzillo, G., additional, Nicita, C., additional, Melis, M., additional, and Iavicoli, S., additional
Published: 2010
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18. The methodology of the Italian HBSC 2010 study (Health Behaviour in School-aged Children)

Author: Lazzeri G., Giacchi M. V., Dalmasso P., Vieno A., Nardone P., Lamberti A., Spinelli A., Cavallo F., Lemma P., Berchialla P., Colombini S., Zambon A., Charrier L., Borraccino A., Pilato V., Rossi S., Pammolli A., Santinello M., Chieco F., Lenzi M., Baglio G., Galeone D., Spizzichino L., Menzano M. T., Scotti M. T., Silani M. T., Teti S., Ciglia A., Di Giacomo M., Spinosa S., Ammirati G., Cauzillo G., Sorrentino G., Azzarito C., La Rocca M., Pizzuti R., Mazzarella G., Di Martino E., Angelini P., Fridel M., Bavcar A., Castronuovo G. C. E., Pascali F., Celata C., Tosi M., Velasco V., Bonfanti M., Coppola L., Giostra G., Ciallella M. L., Caputo M., Viesti E., Rosa G., Anelli S., Meloni S., Senis M. L., Masala R., Cernigliaro A., Rizzo S., Giannoni A. M., Cristofori M., Covarino A. M., D'alessandro G., Piffer S., Fanolla A., Weiss S., Lazzeri, G, Giacchi, M, Dalmasso, P, Vieno, A, Nardone, P, Lamberti, A, Spinelli, A, Cavallo, F, Lemma, P, Berchialla, P, Colombini, S, Zambon, A, Charrier, L, Borraccino, A, Pilato, V, Rossi, S, Pammolli, A, Santinello, M, Chieco, F, Lenzi, M, Baglio, G, Galeone, D, Spizzichino, L, Menzano, M, Scotti, M, Silani, M, Teti, S, Ciglia, A, Di Giacomo, M, Spinosa, S, Ammirati, G, Cauzillo, G, Sorrentino, G, Azzarito, C, La Rocca, M, Pizzuti, R, Mazzarella, G, Di Martino, E, Angelini, P, Fridel, M, Bavcar, A, Castronuovo, G, Pascali, F, Celata, C, Tosi, M, Velasco, V, Bonfanti, M, Coppola, L, Giostra, G, Ciallella, M, Caputo, M, Viesti, E, Rosa, G, Anelli, S, Meloni, S, Senis, M, Masala, R, Cernigliaro, A, Rizzo, S, Giannoni, A, Cristofori, M, Covarino, A, D'Alessandro, G, Piffer, S, Fanolla, A, and Weiss, S
Subjects: Male, School, Sampling Studie, Adolescent, Health Behavior, Child Behavior, Risk Assessment, Teenagers, Sampling Studies, Healthy behaviour, epidemiological surveillance, teenagers, Risk-Taking, Risk Factors, Surveys and Questionnaires, Humans, Surveys and Questionnaire, Sex Distribution, Students, Child, Schools, Risk Factor, Epidemiological surveillance, Teenager, Italy, Health Survey, Health Surveys, Research Design, Adolescent Behavior, Female, Student, Human
Abstract: Italy has participated in the Health Behaviour in School-aged Children (HBSC) study since 2000. These surveys collect data every four years on the well-being and health behaviour of boys and girls aged 11, 13 and 15. Until 2007, the coordination group of the University of Turin, Siena and Padua directly sent the questionnaires to each sampled school to collect the data. The sample of about 4500 students was nationally representative. In 2008 the HBSC became part of the project "Surveys on behavioral risks in children aged 6-17 years", coordinated by the National Institute of Health (ISS) and promoted by the Ministry of Health, in collaboration with the Ministry of Education, University and Research. For the first time, in 2010, the survey was conducted by health workers in collaboration with teachers in all regions with a representative sample, not just at the national level, but also at regional level. In the 2,504 sampled schools, 77,113 students (25,079 eleven-year-old, 26,048 thirteen-year-old and 25,986 fifteen-year-old) completed an anonymous questionnaire. Knowledge of the health-related behaviour of school-aged adolescents may help monitoring and enable policies for young people to be formulated and implemented.

19. Epidemiological surveillance of malignant mesothelioma cases in Italy: incidence and asbestos exposure figures by the Italian mesothelioma registry (ReNaM),La sorveglianza epidemiologica del mesotelioma maligno in Italia: dati d'incidenza ed esposizione ad amianto del Registro nazionale dei mesoteliomi (ReNaM)

Author: Marinaccio, A., Binazzi, A., Cauzillo, G., Chellini, E., Zotti, R., Gennaro, V., Menegozzo, M., Carolina Mensi, Merler, E., Mirabelli, D., Musti, M., Pannelli, F., Romanelli, A., Scarselli, A., Tosi, S., Tumino, R., and Nesti, M.

20. Epidemiologic surveillance of mesothelioma for the prevention of asbestos exposure also in non-traditional settings,Sorveglianza epidemiologica dei mesoteliomi per la prevenzione dell'esposizione ad amianto anche in attività non tradizionalmente coinvolte

Author: Binazzi, A., Scarselli, A., Corfiati, M., Di Marzio, D., Branchi, C., Verardo, M., Mirabelli, D., Gennaro, V., Mensi, C., Schallenberg, G., Merler, E., Zotti, R., Romanelli, A., Chellini, E., Pascucci, C., D Alò, D., Francesco Forastiere, Trafficante, L., Menegozzo, S., Musti, M., Cauzillo, G., Leotta, A., Tumino, R., Melis, M., and Marinaccio, A.

21. Cases of malignant mesothelioma in Italy. Activity and results of the National Registry (ReNaM),I casi di mesotelioma maligno in Italia. Attività e risultati del Registro Nazionale (ReNaM)

Author: Nesti, M., Marinaccio, A., Cauzillo, G., Zotti, R., Gennaro, V., Gorini, G., Menegozzo, M., Mensi, C., Merler, E., Mirabelli, D., Montanaro, F., Musti, M., Pannelli, F., Antonio Romanelli, and Tumino, R.

22. ESPOSIZIONE LAVORATIVA A TREMOLITE IN AREE AL CONFINE CALABRO-LUCANO: RISULTATI DEL CAMPIONAMENTO PERSONALE.

Author: Massaro, T., Macinagrossa, L., Pinca, A., Fiore, S., Lettino, A., Zaccara, A., Caputo, A., Cauzillo, G., Cardascia, F., Cassano, F., and Musti, M.
Abstract: Copyright of Giornale Italiano di Medicina del Lavoro ed Ergonomia is the property of Giornale Italiano di Medicina del Lavoro ed Ergonomia Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Published: 2011

23. Predictors of filing claims and receiving compensation in malignant mesothelioma patients

Author: Domenica Cavone, Gert Schallemberg, Elisa Romeo, Francesco Carrozza, Ugo Fedeli, Italo F. Angelillo, Gabriella Cauzillo, Valerio Gennaro, Corrado Negro, Federico Tallarigo, Enrica Migliore, Luana Trafficante, Alessandro Marinaccio, Claudio Gariazzo, Antonio Romanelli, Iolanda Grappasonni, Gabriella Madeo, Carolina Mensi, Davide Di Marzio, Elisabetta Chellini, Guido Mazzoleni, Sergio Iavicoli, Rosario Tumino, Marina Verardo, Massimo Melis, Marinaccio, A., Gariazzo, C., Di Marzio, D., Iavicoli, S., Verardo, M., Migliore, E., Gennaro, V., Mensi, C., Mazzoleni, G., Schallemberg, G., Fedeli, U., Negro, C., Romanelli, A., Chellini, E., Grappasonni, I., Madeo, G., Romeo, E., Trafficante, L., Carrozza, F., Angelillo, I. F., Cavone, D., Cauzillo, G., Tallarigo, F., Tumino, R., and Melis, M.
Subjects: Mesothelioma, medicine.medical_specialty, media_common.quotation_subject, Asbesto, Logistic regression, medicine.disease_cause, Occupational safety and health, Asbestos, 03 medical and health sciences, 0302 clinical medicine, Occupational Exposure, medicine, Humans, 030212 general & internal medicine, media_common, National Insurance, Insurance system, business.industry, 030503 health policy & services, Health Policy, Public health, Filing, Mesothelioma, Malignant, medicine.disease, Italy, Occupational diseases, Relative risk, Family medicine, 0305 other medical science, business, Welfare
Abstract: Although the predominant occupation origin of mesothelioma is well known, determinant factors involved in filing compensation are scarcely investigated. A linkage between incident mesothelioma cases collected by Italian mesothelioma register (ReNaM) and compensation claims and assignment by Italian national insurance Institute (INAIL) has been conducted for cases diagnosed in the period 2010-2015 and occupational exposure to asbestos. Logistic regression models and decision tree models have been used to identify demographic, diagnostic and anamnestic factors significant for filing and receiving compensation. We have included in the analyses 5019 mesothelioma cases, and among them, 3321 (66.2 %) were found in INAIL archives as mesothelioma cases who fil claims for compensation. The modalities of asbestos exposure, sector of working activities and job type are crucial factors. Furthermore, gender, age at diagnosis, area of residence have been found to be significant predictors of probability to fil claims. Relative risks to fil claims were obtained for the above determinants and conditions to maximize the probability to obtain compensation identified. Our findings demonstrate that there is a need to enforce policies for improving awareness of the occupational origin for mesothelioma cases. Stakeholders, occupational health and safety institutions can play an important role for improving the sensitization regarding the rights of compensation benefits, ensuring the equity and the effectiveness of insurance, welfare and public health systems.
Published: 2020

24. The epidemiological surveillance of malignant mesothelioma in Italy (1993-2015): methods, findings, and research perspectives

Author: Alessandro, Marinaccio, Marisa, Corfiati, Alessandra, Binazzi, Davide, Di Marzio, Michela, Bonafede, Marina, Verardo, Enrica, Migliore, Valerio, Gennaro, Carolina, Mensi, Gert, Schallemberg, Guido, Mazzoleni, Ugo, Fedeli, Corrado, Negro, Antonio, Romanelli, Elisabetta, Chellini, Iolanda, Grappasonni, Cristiana, Pascucci, Gabriella, Madeo, Elisa, Romeo, Luana, Trafficante, Francesco, Carrozza, Italo Francesco, Angelillo, Domenica, Cavone, Gabriella, Cauzillo, Federico, Tallarigo, Rosario, Tumino, Massimo, Melis, Sergio, Stecchi, Marinaccio, A., Corfiati, M., Binazzi, A., Di Marzio, D., Bonafede, M., Verardo, M., Migliore, E., Gennaro, V., Mensi, C., Schallemberg, G., Mazzoleni, G., Fedeli, U., Negro, C., Romanelli, A., Chellini, E., Grappasonni, I., Pascucci, C., Madeo, G., Romeo, E., Trafficante, L., Carrozza, F., Angelillo, I. F., Cavone, D., Cauzillo, G., Tallarigo, F., Tumino, R., and Melis, M.
Subjects: Mesothelioma, Adult, Male, Malignant, Incidence, Mesothelioma, Malignant, Asbestos, Asbesto, Middle Aged, Occupational Disease, Occupational Diseases, asbesto, Epidemiological surveillance system, Italy, Female, Humans, Occupational Exposure, Population Surveillance, Registries, epidemiological surveillance system, mesothelioma, Human
Abstract: BACKGROUND: As a legacy of the large asbestos consumption until the definitive ban in 1992, Italy had to tackle a real epidemic of asbestos related diseases. The Italian National Registry of Malignant Mesotheliomas (ReNaM) is a permanent surveillance system of mesothelioma incidence, with a regional structure. Aims, assignments and territorial network of ReNaM are described, as well as data collection, recording and coding procedures. OBJECTIVES: To describe the Italian epidemiological surveillance system of mesothelioma incidence, to provide updated data about occurrence of malignant mesothelioma in Italy, and to discuss goals, attainments, and expectations of registering occupational cancer. DESIGN: Analysis of data by malignant mesothelioma incident cases surveillance system. SETTING AND PARTICIPANTS: Italy, network of regional sur-veillance system, all Italian regions. MAIN OUTCOME MEASURES: A Regional Operating Centre (COR) is currently established in all the Italian regions, actively searching incident malignant mesothelioma cases from health care institutions. Occupational history, lifestyle habits, and residential history are obtained using a standardized questionnaire, administered to the subject or to the next of kin by a trained interviewer. The extent of dataset, epide-miological parameters, and occupations involved are reported updated at 31.12.2016, and standardized incidence rates are calculated. RESULTS: At December 2016, ReNaM has collected 27,356 malignant mesothelioma cases, referring to the period of incidence between 1993 and 2015. The modalities of exposure to asbestos have been investigated for 21,387 (78%) and an occupational exposure has been defined for around 70% of defined cases (14,818). CONCLUSIONS: The Italian experience shows that epidemiological systematic surveillance of asbestos related diseases incidence has a key importance for assessing and monitoring the public health impact of occupational and/or environmental hazards, programming preventive interventions, including remediation plans and information campaigns, and supporting the efficiency of insurance and welfare system. Monitor-ing the incidence of malignant mesothelioma through a specialized cancer registry is essential to follow-up the health effects of changing modalities and extent of occupational exposures over years and of environmental contamination. Such consolidated surveillance system is recommended also for occupational cancers with low aetiological fraction.
Published: 2020

25. The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure

Author: Marinaccio, Alessandro, Corfiati, Marisa, Binazzi, Alessandra, Di Marzio, Davide, Scarselli, Alberto, Ferrante, Pierpaolo, Bonafede, Michela, Verardo, Marina, Mirabelli, Dario, Gennaro, Valerio, Mensi, Carolina, Schallemberg, Gert, Mazzoleni, Guido, Merler, Enzo, Girardi, Paolo, Negro, Corrado, D'Agostin, Flavia, Romanelli, Antonio, Chellini, Elisabetta, Silvestri, Stefano, Pascucci, Cristiana, Calisti, Roberto, Stracci, Fabrizio, Romeo, Elisa, Ascoli, Valeria, Trafficante, Luana, Carrozza, Francesco, Angelillo, Italo Francesco, Cavone, Domenica, Cauzillo, Gabriella, Tallarigo, Federico, Tumino, Rosario, Melis, Massimo, Iavicoli, Sergio, Detragiache, E, Merletti, F, Gangemi, M, Stura, A, Brentisci, C, Diglio, Gc, Macerata, V, Gilardetti, M, Lazzarotto, A, Benfatto, L, Bianchelli, M, Mazzucco, G, Campi, M, Malacarne, D, Camposeragno, D, Giorgio, Fd, Canessa, P, Consonni, D, Pesatori, A, Riboldi, L, Bressan, V, Gioffrè, F, Ballarinl, M, Chermaz, C, Michieli, P, Mangone, L, Storchi, C, Sala, O, Badiali, A, Cacciarini, V, Giovannetti, L, Martini, A, Grappasonni, I, Masanotti, G, D'Alo', D, Petrucci, M, Davoli, M, Forastiere, F, Cavariani, F, Ancona, L, Giammarco, Ad, Menegozzo, S, Canfora, M, Santoro, M, Viscardi, F, Brangi, A, Cozza, V, Vimercati, L, Lio, S, Cascone, G, Frasca, G, Giurdanella, M, Martorana, C, Nicita, C, Rollo, P, Spata, E, Dardanoni, G, Scondotto, S, Nieddu, V, Pergola, M, Stecchi, S., Marinaccio, A, Corfiati, M, Binazzi, A, Di Marzio, D, Scarselli, A, Ferrante, P, Bonafede, M, Verardo, M, Mirabelli, D, Gennaro, V, Mensi, C, Schallemberg, G, Mazzoleni, G, Merler, E, Girardi, P, Negro, C, D'Agostin, F, Romanelli, A, Chellini, E, Silvestri, S, Pascucci, C, Calisti, R, Stracci, F, Romeo, E, Ascoli, V, Trafficante, L, Carrozza, F, Angelillo, If, Cavone, D, Cauzillo, G, Tallarigo, F, Tumino, R, Melis, M, Iavicoli, S., Marinaccio, Alessandro, Corfiati, Marisa, Binazzi, Alessandra, Di Marzio, Davide, Scarselli, Alberto, Ferrante, Pierpaolo, Bonafede, Michela, Verardo, Marina, Mirabelli, Dario, Gennaro, Valerio, Mensi, Carolina, Schallemberg, Gert, Mazzoleni, Guido, Merler, Enzo, Girardi, Paolo, Negro, Corrado, D'Agostin, Flavia, Romanelli, Antonio, Chellini, Elisabetta, Silvestri, Stefano, Pascucci, Cristiana, Calisti, Roberto, Stracci, Fabrizio, Romeo, Elisa, Ascoli, Valeria, Trafficante, Luana, Carrozza, Francesco, Angelillo, Italo Francesco, Cavone, Domenica, Cauzillo, Gabriella, Tallarigo, Federico, Tumino, Rosario, Melis, Massimo, and Iavicoli, Sergio
Subjects: medicine.medical_specialty, asbestos, gender, mesothelioma, asbestos, gender, mesothelioma, medicine.disease_cause, Asbestos, asbesto, 03 medical and health sciences, 0302 clinical medicine, Epidemiology, Medicine, 030212 general & internal medicine, Mesothelioma, Workplace, Modalities, business.industry, Incidence (epidemiology), Mortality rate, Environmental and Occupational Health, Public Health, Environmental and Occupational Health, medicine.disease, 030220 oncology & carcinogenesis, Workforce, Etiology, Public Health, Settore SECS-S/01 - Statistica, business, Demography
Abstract: IntroductionThe epidemiology of gender differences for mesothelioma incidence has been rarely discussed in national case lists. In Italy an epidemiological surveillance system (ReNaM) is working by the means of a national register.MethodsIncident malignant mesothelioma (MM) cases in the period 1993 to 2012 were retrieved from ReNaM. Gender ratio by age class, period of diagnosis, diagnostic certainty, morphology and modalities of asbestos exposure has been analysed using exact tests for proportion. Economic activity sectors, jobs and territorial distribution of mesothelioma cases in women have been described and discussed. To perform international comparative analyses, the gender ratio of mesothelioma deaths was calculated by country from the WHO database and the correlation with the mortality rates estimated.ResultsIn the period of study a case list of 21 463 MMs has been registered and the modalities of asbestos exposure have been investigated for 16 458 (76.7%) of them. The gender ratio (F/M) was 0.38 and 0.70 (0.14 and 0.30 for occupationally exposed subjects only) for pleural and peritoneal cases respectively. Occupational exposures for female MM cases occurred in the chemical and plastic industry, and mainly in the non-asbestos textile sector. Gender ratio proved to be inversely correlated with mortality rate among countries.ConclusionsThe consistent proportion of mesothelioma cases in women in Italy is mainly due to the relevant role of non-occupational asbestos exposures and the historical presence of the female workforce in several industrial settings. Enhancing the awareness of mesothelioma aetiology in women could support the effectiveness of welfare system and prevention policies.
Published: 2018

26. Malignant mesothelioma due to non-occupational asbestos exposure from the Italian national surveillance system (ReNaM): epidemiology and public health issues

Author: Marinaccio, Alessandro, Binazzi, Alessandra, Bonafede, Michela, Corfiati, Marisa, Marzio, Davide Di, Scarselli, Alberto, Verardo, Marina, Mirabelli, Dario, Gennaro, Valerio, Mensi, Carolina, Schallemberg, Gert, Merler, Enzo, Negro, Corrado, Romanelli, Antonio, Chellini, Elisabetta, Silvestri, Stefano, Cocchioni, Mario, Pascucci, Cristiana, Stracci, Fabrizio, Ascoli, Valeria, Trafficante, Luana, Angelillo, Italo, Musti, Marina, Cavone, Domenica, Cauzillo, Gabriella, Tallarigo, Federico, Tumino, Rosario, Melis, Massimo, ReNaM Working Group, Marinaccio, Alessandro, Binazzi, Alessandra, Bonafede, Michela, Corfiati, Marisa, Di Marzio, Davide, Scarselli, Alberto, Verardo, Marina, Mirabelli, Dario, Gennaro, Valerio, Mensi, Carolina, Schallemberg, Gert, Merler, Enzo, Negro, Corrado, Romanelli, Antonio, Chellini, Elisabetta, Silvestri, Stefano, Cocchioni, Mario, Pascucci, Cristiana, Stracci, Fabrizio, Ascoli, Valeria, Trafficante, Luana, Angelillo, Italo, Musti, Marina, Cavone, Domenica, Cauzillo, Gabriella, Tallarigo, Federico, Tumino, Rosario, Melis, Massimo, Marinaccio, A, Binazzi, A, Bonafede, M, Corfiati, M, Di Marzio, D, Scarselli, A, Verardo, M, Mirabelli, D, Gennaro, V, Mensi, C, Schallemberg, G, Merler, E, Negro, C, Romanelli, A, Chellini, E, Silvestri, S, Cocchioni, M, Pascucci, C, Stracci, F, Ascoli, V, Trafficante, L, Angelillo, Italo Francesco, Musti, M, Cavone, D, Cauzillo, G, Tallarigo, F, Tumino, R, Melis, M, and ReNaM Working, Group
Subjects: Male, Mesothelioma, Pathology, Lung Neoplasms, Non occupational, environmental exposure, Malignant Mesothelioma, medicine.disease_cause, Epidemiology, Medicine, Child, new-caledonia, risk, Aged, 80 and over, Incidence (epidemiology), Incidence, Environmental exposure, cohort, Middle Aged, tremolite, Italy, Child, Preschool, Population Surveillance, national surveillance, Environmental Pollutants, Female, Public Health, western-australia, Adult, medicine.medical_specialty, Adolescent, Pleural Neoplasms, Asbestos, Young Adult, Sex Factors, Environmental health, Occupational Exposure, Humans, Aged, business.industry, Pleural mesothelioma, Public health, Mesothelioma, Malignant, Public Health, Environmental and Occupational Health, Infant, Newborn, Infant, Malignant Mesothelioma, asbestos, national surveillance, medicine.disease, mortality, pleural mesothelioma, workers, wittenoom, business
Abstract: Introduction Italy produced and imported a large amount of raw asbestos, up to the ban in 1992, with a peak in the period between 1976 and 1980 at about 160 000 tons/year. The National Register of Mesotheliomas (ReNaM, “Registro Nazionale dei Mesoteliomi” in Italian), a surveillance system of mesothelioma incidence, has been active since 2002, operating through a regional structure. Methods The Operating Regional Center (COR) actively researches cases and defines asbestos exposure on the basis of national guidelines. Diagnostic, demographic and exposure characteristics of non-occupationally exposed cases are analysed and described with respect to occupationally exposed cases. Results Standardised incidence rates for pleural mesothelioma in 2008 were 3.84 (per 100 000) for men and 1.45 for women, respectively. Among the 15 845 mesothelioma cases registered between 1993 and 2008, exposure to asbestos fibres was investigated for 12 065 individuals (76.1%), identifying 530 (4.4%) with familial exposure (they lived with an occupationally exposed cohabitant), 514 (4.3%) with environmental exposure to asbestos (they lived near sources of asbestos pollution and were never occupationally exposed) and 188 (1.6%) exposed through hobby-related or other leisure activities. Clusters of cases due to environmental exposure are mainly related to the presence of asbestos-cement industry plants (Casale Monferrato, Broni, Bari), to shipbuilding and repair activities (Monfalcone, Trieste, La Spezia, Genova) and soil contamination (Biancavilla in Sicily). Conclusions Asbestos pollution outside the workplace contributes significantly to the burden of asbestos-related diseases, suggesting the need to prevent exposures and to discuss how to deal with compensation rights for malignant mesothelioma cases induced by non-occupational exposure to asbestos.
Published: 2015

27. The epidemiological surveillance of malignant mesothelioma in Italy (1993-2015): methods, findings, and research perspectives.

Author: Marinaccio A, Corfiati M, Binazzi A, Di Marzio D, Bonafede M, Verardo M, Migliore E, Gennaro V, Mensi C, Schallemberg G, Mazzoleni G, Fedeli U, Negro C, Romanelli A, Chellini E, Grappasonni I, Pascucci C, Madeo G, Romeo E, Trafficante L, Carrozza F, Angelillo IF, Cavone D, Cauzillo G, Tallarigo F, Tumino R, and Melis M
Subjects: Adult, Female, Humans, Incidence, Italy epidemiology, Male, Middle Aged, Occupational Diseases epidemiology, Occupational Exposure statistics & numerical data, Population Surveillance, Registries, Mesothelioma, Malignant epidemiology
Abstract: Background: as a legacy of the large asbestos consumption until the definitive ban in 1992, Italy had to tackle a real epidemic of asbestos related diseases. The Italian National Registry of Malignant Mesotheliomas (ReNaM) is a permanent surveillance system of mesothelioma incidence, with a regional structure. Aims, assignments and territorial network of ReNaM are described, as well as data collection, recording and coding procedures., Objectives: to describe the Italian epidemiological surveillance system of mesothelioma incidence, to provide updated data about occurrence of malignant mesothelioma in Italy, and to discuss goals, attainments, and expectations of registering occupational cancer., Design: analysis of data by malignant mesothelioma incident cases surveillance system., Setting and Participants: Italy, network of regional surveillance system, all Italian regions., Main Outcome Measures: a Regional Operating Centre (COR) is currently established in all the Italian regions, actively searching incident malignant mesothelioma cases from health care institutions. Occupational history, lifestyle habits, and residential history are obtained using a standardized questionnaire, administered to the subject or to the next of kin by a trained interviewer. The extent of dataset, epidemiological parameters, and occupations involved are reported updated at 31.12.2016, and standardized incidence rates are calculated., Results: at December 2016, ReNaM has collected 27,356 malignant mesothelioma cases, referring to the period of incidence between 1993 and 2015. The modalities of exposure to asbestos have been investigated for 21,387 (78%) and an occupational exposure has been defined for around 70% of defined cases (14,818)., Conclusions: the Italian experience shows that epidemiological systematic surveillance of asbestos related diseases incidence has a key importance for assessing and monitoring the public health impact of occupational and/or environmental hazards, programming preventive interventions, including remediation plans and information campaigns, and supporting the efficiency of insurance and welfare system. Monitoring the incidence of malignant mesothelioma through a specialized cancer registry is essential to follow-up the health effects of changing modalities and extent of occupational exposures over years and of environmental contamination. Such consolidated surveillance system is recommended also for occupational cancers with low aetiological fraction.
Published: 2020
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28. Letter concerning: 'Response to: 'The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure' by Marinaccio et al '.

Author: Marinaccio A, Corfiati M, Binazzi A, Di Marzio D, Scarselli A, Ferrante P, Bonafede M, Verardo M, Mirabelli D, Gennaro V, Mensi C, Schallemberg G, Mazzoleni G, Merler E, Girardi P, Negro C, D'Agostin F, Romanelli A, Chellini E, Silvestri S, Pascucci C, Calisti R, Stracci F, Romeo E, Ascoli V, Trafficante L, Carrozza F, Angelillo I, Cavone D, Cauzillo G, Tallarigo F, Tumino R, Melis M, and Iavicoli S
Subjects: Female, Humans, Asbestos, Lung Neoplasms, Mesothelioma
Abstract: Competing Interests: Competing interests: None declared.
Published: 2018
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29. The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure.

Author: Marinaccio A, Corfiati M, Binazzi A, Di Marzio D, Scarselli A, Ferrante P, Bonafede M, Verardo M, Mirabelli D, Gennaro V, Mensi C, Schallemberg G, Mazzoleni G, Merler E, Girardi P, Negro C, D'Agostin F, Romanelli A, Chellini E, Silvestri S, Pascucci C, Calisti R, Stracci F, Romeo E, Ascoli V, Trafficante L, Carrozza F, Angelillo IF, Cavone D, Cauzillo G, Tallarigo F, Tumino R, Melis M, and Iavicoli S
Subjects: Adult, Aged, Aged, 80 and over, Female, Humans, Italy epidemiology, Lung Neoplasms chemically induced, Male, Mesothelioma chemically induced, Mesothelioma, Malignant, Middle Aged, Occupational Exposure statistics & numerical data, Registries, Risk Factors, Sex Factors, Asbestos adverse effects, Lung Neoplasms epidemiology, Mesothelioma epidemiology, Occupational Exposure adverse effects
Abstract: Introduction: The epidemiology of gender differences for mesothelioma incidence has been rarely discussed in national case lists. In Italy an epidemiological surveillance system (ReNaM) is working by the means of a national register., Methods: Incident malignant mesothelioma (MM) cases in the period 1993 to 2012 were retrieved from ReNaM. Gender ratio by age class, period of diagnosis, diagnostic certainty, morphology and modalities of asbestos exposure has been analysed using exact tests for proportion. Economic activity sectors, jobs and territorial distribution of mesothelioma cases in women have been described and discussed. To perform international comparative analyses, the gender ratio of mesothelioma deaths was calculated by country from the WHO database and the correlation with the mortality rates estimated., Results: In the period of study a case list of 21 463 MMs has been registered and the modalities of asbestos exposure have been investigated for 16 458 (76.7%) of them. The gender ratio (F/M) was 0.38 and 0.70 (0.14 and 0.30 for occupationally exposed subjects only) for pleural and peritoneal cases respectively. Occupational exposures for female MM cases occurred in the chemical and plastic industry, and mainly in the non-asbestos textile sector. Gender ratio proved to be inversely correlated with mortality rate among countries., Conclusions: The consistent proportion of mesothelioma cases in women in Italy is mainly due to the relevant role of non-occupational asbestos exposures and the historical presence of the female workforce in several industrial settings. Enhancing the awareness of mesothelioma aetiology in women could support the effectiveness of welfare system and prevention policies., Competing Interests: Competing interests: The following authors reported that they have served as expert witness for the public prosecutor in court trials on asbestos-related diseases: EM, DM, SS, VG, CM, RC., (© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)
Published: 2018
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30. [Health impact of asbestos fibres naturally occurring in Mount Pollino area (Basilicata Region, Southern Italy)].

Author: Caputo A, De Santis M, Manno V, Cauzillo G, Bruni BM, Palumbo L, Conti S, and Comba P
Subjects: Aged, Aged, 80 and over, Asbestosis mortality, Environmental Exposure, Environmental Monitoring, Female, Geography, Medical, Geological Phenomena, Hospitalization statistics & numerical data, Humans, Incidence, Italy, Male, Mesothelioma etiology, Mesothelioma mortality, Mineral Fibers toxicity, Ovarian Neoplasms mortality, Population Surveillance, Respiratory Tract Neoplasms etiology, Respiratory Tract Neoplasms mortality, Asbestos toxicity, Asbestosis etiology, Environmental Pollutants toxicity
Abstract: Objectives: to estimate the health impact of asbestos fibres naturally occurring in Mount Pollino area (Basilicata Region, Southern Italy)., Design: geographic mortality, hospitalization, and incidence study. Setting and participant s: population resident in 12 Municipalities of Mount Pollino area with naturally occurring asbestos fibres., Main Outcome Measures: standardized mortality ratio (SMR) and standardized hospitalization rate (SHR) for asbestos-related diseases; standardized incidence ratio (SIR) for mesotheliomas. Result s: in the area of Mount Pollino, where asbestos fibres naturally occur, especially in the sub-area in which fibres are close to dwellings and settlements, it was observed: • a significant excess of mesothelioma incidence (SIR: 208; CI95% 111-355; 13 observed); • a non-significant excess of hospitalization for malignant pleural neoplasms (SHR: 176; CI95% 93-335; 9 observed); • a significant excess for mortality and hospitalization for pneumoconiosis (SMR: 534; CI95% 345-824; 20 observed - SHR: 245; CI95% 149-405; 15 observed); • a significant excess for hospitalization (SHR: 852; CI95% 290-2,506; 3 observed) for asbestosis., Conclusion: it is necessary to continue environmental monitoring and environmental remediation in the area with higher asbestos exposure. It is suggested to implement a permanent process of epidemiological surveillance in this same area. A communication plan with local administrators, general practitioners, school teachers, media, and the resident population at large should be realized.
Published: 2018
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31. Malignant mesothelioma due to non-occupational asbestos exposure from the Italian national surveillance system (ReNaM): epidemiology and public health issues.

Author: Marinaccio A, Binazzi A, Bonafede M, Corfiati M, Di Marzio D, Scarselli A, Verardo M, Mirabelli D, Gennaro V, Mensi C, Schallemberg G, Merler E, Negro C, Romanelli A, Chellini E, Silvestri S, Cocchioni M, Pascucci C, Stracci F, Ascoli V, Trafficante L, Angelillo I, Musti M, Cavone D, Cauzillo G, Tallarigo F, Tumino R, and Melis M
Subjects: Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Incidence, Infant, Infant, Newborn, Italy epidemiology, Lung Neoplasms epidemiology, Male, Mesothelioma epidemiology, Mesothelioma, Malignant, Middle Aged, Occupational Exposure adverse effects, Pleural Neoplasms epidemiology, Population Surveillance, Public Health, Sex Factors, Young Adult, Asbestos adverse effects, Environmental Exposure adverse effects, Environmental Pollutants adverse effects, Lung Neoplasms etiology, Mesothelioma etiology, Pleural Neoplasms etiology
Abstract: Introduction: Italy produced and imported a large amount of raw asbestos, up to the ban in 1992, with a peak in the period between 1976 and 1980 at about 160,000 tons/year. The National Register of Mesotheliomas (ReNaM, "Registro Nazionale dei Mesoteliomi" in Italian), a surveillance system of mesothelioma incidence, has been active since 2002, operating through a regional structure., Methods: The Operating Regional Center (COR) actively researches cases and defines asbestos exposure on the basis of national guidelines. Diagnostic, demographic and exposure characteristics of non-occupationally exposed cases are analysed and described with respect to occupationally exposed cases., Results: Standardised incidence rates for pleural mesothelioma in 2008 were 3.84 (per 100,000) for men and 1.45 for women, respectively. Among the 15,845 mesothelioma cases registered between 1993 and 2008, exposure to asbestos fibres was investigated for 12,065 individuals (76.1%), identifying 530 (4.4%) with familial exposure (they lived with an occupationally exposed cohabitant), 514 (4.3%) with environmental exposure to asbestos (they lived near sources of asbestos pollution and were never occupationally exposed) and 188 (1.6%) exposed through hobby-related or other leisure activities. Clusters of cases due to environmental exposure are mainly related to the presence of asbestos-cement industry plants (Casale Monferrato, Broni, Bari), to shipbuilding and repair activities (Monfalcone, Trieste, La Spezia, Genova) and soil contamination (Biancavilla in Sicily)., Conclusions: Asbestos pollution outside the workplace contributes significantly to the burden of asbestos-related diseases, suggesting the need to prevent exposures and to discuss how to deal with compensation rights for malignant mesothelioma cases induced by non-occupational exposure to asbestos., (Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.)
Published: 2015
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32. Epidemiological patterns of asbestos exposure and spatial clusters of incident cases of malignant mesothelioma from the Italian national registry.

Author: Corfiati M, Scarselli A, Binazzi A, Di Marzio D, Verardo M, Mirabelli D, Gennaro V, Mensi C, Schallemberg G, Merler E, Negro C, Romanelli A, Chellini E, Silvestri S, Cocchioni M, Pascucci C, Stracci F, Romeo E, Trafficante L, Angelillo I, Menegozzo S, Musti M, Cavone D, Cauzillo G, Tallarigo F, Tumino R, Melis M, Iavicoli S, and Marinaccio A
Subjects: Adolescent, Adult, Aged, Aged, 80 and over, Bayes Theorem, Child, Child, Preschool, Cluster Analysis, Female, Geography, Humans, Incidence, Infant, Infant, Newborn, Italy epidemiology, Male, Mesothelioma, Malignant, Middle Aged, Registries, Spatial Analysis, Young Adult, Asbestos adverse effects, Environmental Exposure adverse effects, Lung Neoplasms epidemiology, Lung Neoplasms etiology, Mesothelioma epidemiology, Mesothelioma etiology
Abstract: Background: Previous ecological spatial studies of malignant mesothelioma cases, mostly based on mortality data, lack reliable data on individual exposure to asbestos, thus failing to assess the contribution of different occupational and environmental sources in the determination of risk excess in specific areas. This study aims to identify territorial clusters of malignant mesothelioma through a Bayesian spatial analysis and to characterize them by the integrated use of asbestos exposure information retrieved from the Italian national mesothelioma registry (ReNaM)., Methods: In the period 1993 to 2008, 15,322 incident cases of all-site malignant mesothelioma were recorded and 11,852 occupational, residential and familial histories were obtained by individual interviews. Observed cases were assigned to the municipality of residence at the time of diagnosis and compared to those expected based on the age-specific rates of the respective geographical area. A spatial cluster analysis was performed for each area applying a Bayesian hierarchical model. Information about modalities and economic sectors of asbestos exposure was analyzed for each cluster., Results: Thirty-two clusters of malignant mesothelioma were identified and characterized using the exposure data. Asbestos cement manufacturing industries and shipbuilding and repair facilities represented the main sources of asbestos exposure, but a major contribution to asbestos exposure was also provided by sectors with no direct use of asbestos, such as non-asbestos textile industries, metal engineering and construction. A high proportion of cases with environmental exposure was found in clusters where asbestos cement plants were located or a natural source of asbestos (or asbestos-like) fibers was identifiable. Differences in type and sources of exposure can also explain the varying percentage of cases occurring in women among clusters., Conclusions: Our study demonstrates shared exposure patterns in territorial clusters of malignant mesothelioma due to single or multiple industrial sources, with major implications for public health policies, health surveillance, compensation procedures and site remediation programs.
Published: 2015
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33. Pleural malignant mesothelioma epidemic: incidence, modalities of asbestos exposure and occupations involved from the Italian National Register.

Author: Marinaccio A, Binazzi A, Marzio DD, Scarselli A, Verardo M, Mirabelli D, Gennaro V, Mensi C, Riboldi L, Merler E, Zotti RD, Romanelli A, Chellini E, Silvestri S, Pascucci C, Romeo E, Menegozzo S, Musti M, Cavone D, Cauzillo G, Tumino R, Nicita C, Melis M, and Iavicoli S
Subjects: Adult, Age Factors, Aged, Asbestos adverse effects, Asbestos chemistry, Epidemics, Female, Humans, Italy epidemiology, Male, Mesothelioma chemically induced, Middle Aged, Occupational Diseases chemically induced, Occupational Exposure adverse effects, Pleural Neoplasms chemically induced, Population Surveillance, Mesothelioma epidemiology, Mesothelioma pathology, Pleural Neoplasms epidemiology, Pleural Neoplasms pathology
Abstract: Due to the large scale use of asbestos (more than 3.5 million tons produced or imported until its definitive banning in 1992), a specific national surveillance system of mesothelioma incident cases is active in Italy, with direct and individual anamnestic etiological investigation. In the period between 1993 and 2004, a case-list of 8,868 pleural MM was recorded by the Italian National Register (ReNaM) and the modalities of exposure to asbestos fibres have been investigated for 6,603 of them. Standardized incidence rates are 3.49 (per 100,000 inhabitants) for men and 1.25 for women, with a wide regional variability. Occupational asbestos exposure was in 69.3% of interviewed subjects (N = 4,577 cases), while 4.4% was due to cohabitation with someone (generally, the husband) occupationally exposed, 4.7% by environmental exposure from living near a contamination source and 1.6% during a leisure activity. In the male group, 81.5% of interviewed subjects exhibit an occupational exposure. In the exposed workers, the median year of first exposure was 1957, and mean latency was 43.7 years. The analysis of exposures by industrial sector focuses on a decreasing trend for those traditionally signaled as "at risk" (asbestos-cement industry, shipbuilding and repair and railway carriages maintenance) and an increasing trend for the building construction sector. The systematic mesothelioma surveillance system is relevant for the prevention of the disease and for supporting an efficient compensation system. The existing experience on all-too-predictable asbestos effects should be transferred to developing countries where asbestos use is spreading., (Copyright © 2011 UICC.)
Published: 2012
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34. Governance of preventive Health Intervention and On time Verification of its Efficiency: the GIOVE Study.

Author: Mennini FS, Baio G, Montagano G, Cauzillo G, Locuratolo F, Becce G, Gitto L, Marcellusi A, Zweifel P, Capone A, and Favato G
Abstract: Objectives: The GIOVE Study was aimed to the achievement of allocative efficiency of the budget allocated to the prevention of human papillomavirus (HPV)-induced diseases. An ex-ante determination of the most efficient allocation of resources between screening and multicohort quadrivalent immunisation programmes was followed by the ex-post assessment of the allocative efficiency actually achieved after a 12-month period., Design: A bound optimisation model was developed to determine the ex-ante allocative efficiency of resources. The alternatives compared were the screening programme alone and the quadrivalent immunisation with access to screening. A sensitivity analysis was carried out to assess the uncertainty associated with the main inputs of the model. Subsequently, a cohort of girls with a complete recorded vaccination history were enrolled in an observational retrospective study for 18 months to ensure full compliance with the recommended schedule of vaccination (0, 2, 6 months) within a 12-month time horizon., Setting: Basilicata region, in the south of Italy., Participants: 12 848 girls aged 12, 15, 18 or 25 years., Intervention: Immunisation with quadrivalent anti-HPV vaccine., Outcome Measures: The vaccination coverage rate was considered to be the indicator of the best achievable benefit, given the budgetary constraints., Results: Assuming a vaccine price of €100 per dose, a vaccination coverage rate of 59.6% was required for the most effective allocation of resources. The optimal rate of coverage was initially in favour of the multicohort strategy of vaccination against HPV (72.8%±2%). When the price paid for the quadrivalent vaccine dropped to €85 per dose, the most efficient coverage rate (69.5%) shifted closer to the immunisation rate actually achieved during the 12-month observation period., Conclusions: The bound optimisation model demonstrated to be a useful approach to the ex-ante allocation and the ex-post assessment of the resources allocated to the implementation of a multicohort quadrivalent anti-HPV vaccination programme.
Published: 2012
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35. Analysis of latency time and its determinants in asbestos related malignant mesothelioma cases of the Italian register.

Author: Marinaccio A, Binazzi A, Cauzillo G, Cavone D, Zotti RD, Ferrante P, Gennaro V, Gorini G, Menegozzo M, Mensi C, Merler E, Mirabelli D, Montanaro F, Musti M, Pannelli F, Romanelli A, Scarselli A, and Tumino R
Subjects: Adult, Aged, Epidemiologic Methods, Female, Humans, Italy epidemiology, Male, Middle Aged, Pericardium, Time Factors, Asbestos toxicity, Environmental Exposure adverse effects, Heart Neoplasms epidemiology, Mesothelioma epidemiology, Peritoneal Neoplasms epidemiology, Pleural Neoplasms epidemiology, Testicular Neoplasms epidemiology
Abstract: Italy was an important producer of raw asbestos until 1992 (when it was banned) and it is now experiencing severe public health consequences due to large-scale industrial use of asbestos in shipbuilding and repair, asbestos-cement production, railways, buildings, chemicals and many other industrial sectors. Latency of malignant mesothelioma generally shows a large variability and the relationship with the modality of asbestos exposure is still not fully clarified. We present an analysis of latency period among the case list collected by the Italian mesothelioma register (ReNaM) in the period of diagnosis 1993-2001 (2544 malignant mesothelioma (MM) cases with asbestos exposure history). Exposure is assessed retrospectively by interview. Statistical univariate analyses were performed to estimate median and variability measures of latency time by anatomical site, gender and diagnosis period. The role of diagnostic confidence level, the morphology of the tumour and the modalities of asbestos exposure were verified in a regression multivariate model. We found a median latency period of 44.6 years increasing in recent years with a linear trend. Anatomical site, gender and morphology were not relevant for MM latency time whereas a shorter latency period was documented among occupationally exposed subjects (43 years) with respect to environmentally and household exposed ones (48 years).
Published: 2007
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36. [Epidemiological surveillance of malignant mesothelioma cases in Italy: incidence and asbestos exposure figures by the Italian mesothelioma registry (ReNaM)].

Author: Marinaccio A, Binazzi A, Cauzillo G, Chellini E, De Zotti R, Gennaro V, Menegozzo M, Mensi C, Merler E, Mirabelli D, Musti M, Pannelli F, Romanelli A, Scarselli A, Tosi S, Tumino R, and Nesti M
Subjects: Aged, Female, Humans, Incidence, Italy epidemiology, Male, Middle Aged, Population Surveillance, Registries, Asbestos adverse effects, Mesothelioma epidemiology, Mesothelioma etiology, Occupational Diseases epidemiology, Occupational Diseases etiology, Occupational Exposure adverse effects, Pleural Neoplasms epidemiology, Pleural Neoplasms etiology
Abstract: The Study describes the epidemiological surveillance of mesothelioma cases carried out by the Italian mesothelioma register (ReNaM). A Regional Operating Centre (COR) is present in nearly all Italian regions (17 out of 20) and it collects malignant mesothelioma cases and investigate the modalities of asbestos exposure by using a structured questionnaire. The register produces malignant mesothelioma incidence measures and analyses of the modalities of the asbestos exposure. The standardized incidence rate of malignant mesothelioma in 2001 was 2.98 (in 100,000 inhabitants) among men and 0.98 among women; a professional (certain, probable, possible) exposure has been detected in 67.4% of defined cases. In addition to the conventional sectors (shipbuilding, railways repair and demolition, asbestos-cement production), also textile, building, transport, chemical and glass industries, petroleum and sugar refineries, electricity production and distribution plants are getting involved. Despite the absence of some regions completing the national coverage and the non homogeneity in collecting and coding data, the epidemiological surveillance of malignant mesothelioma carried out by ReNaM is an important tool for the scientific knowledge and the prevention of asbestos-related diseases.
Published: 2007

37. [Consensus Conference "Health surveillance of resident population exposed to tremolite in Local Health Unit 3 territory Lagonegro, PZ". Rome 22-23 February 2005].

Author: Musti M, Bruno C, Cassano F, Caputo A, Cauzillo G, Cavone D, Convertini L, De Blasio A, De Mei B, Marra M, Montagano G, Schettino B, Zona A, and Comba P
Subjects: Asbestosis epidemiology, Asbestosis prevention & control, Humans, Rome epidemiology, Asbestos, Amphibole adverse effects, Asbestosis etiology, Environmental Exposure adverse effects, Population Surveillance, Practice Guidelines as Topic
Abstract: Herein is reported the health surveillance document agreed upon during the Consensus Conference held in Rome at the Istituto Superiore di Sanità last year. The aim of the consensus conference was to define guidelines for epidemiologic and health surveillance of the resident population in the area of the Basilicata region exposed to tremolite pollution (Local Health Unit 3 territory Lagonegro, PZ). The health surveillance program for residents and the nested epidemiologic study evaluates for each resident willing to participate, individual exposure with a personal dosimeter, as well as the prevalence of obstructive, restrictive or mixed pulmonary functional patterns, searching for fiber and asbestos bodies in induced-sputum, the prevalence of non malignant asbestos disturbances related to pleural anomalies and, last but not least, provides information on risks and sensitization, advising on personal behaviour that could reduce the risks.
Published: 2006

38. [Pleural mesothelioma and environmental exposure to mineral fibres: the case of a rural area in the Basilicata region, Italy].

Author: Pasetto R, Bruni B, Bruno C, Cauzillo G, Cavone D, Convertini L, De Mei B, Marconi A, Montagano G, Musti M, Paoletti L, and Comba P
Subjects: Humans, Italy, Mesothelioma epidemiology, Mineral Fibers adverse effects, Pleural Neoplasms epidemiology, Risk Assessment, Rural Population, Asbestos adverse effects, Asbestos, Amphibole adverse effects, Environmental Exposure adverse effects, Mesothelioma etiology, Pleural Neoplasms etiology
Abstract: The main aspects of the sites characterized by environmental exposure to mineral asbestiform fibres are described. Several adverse health effects including high incidence of pleural mesothelioma are reported. The average concentration of airborne fibres is generally low but it rises significantly in association with mechanical disturb of materials with fibres. Multiple sources of exposure have been identified, fibres can be found in the soil and in many materials locally used, mainly in buildings. Three mesothelioma cases were observed in a small rural area of the Basilicata region (Italy). Two of them had a possible occupational exposure to asbestos, the third had a proved environmental exposure to tremolite. This fibre, found in the area, is the same observed in two of the three biological samples analysed.
Published: 2004

39. [Health surveillance (health intervention) in workers formerly exposed to asbestos (formerly employed at Materit-Ferrandina)].

Author: Convertini L, Cavone D, Cauzillo G, Montagano G, Panarace L, Serio G, and Musti M
Subjects: Adult, Aged, Construction Materials, Female, Humans, Italy, Male, Middle Aged, Population Surveillance, Asbestos toxicity, Occupational Exposure adverse effects
Abstract: Results of an intervention of medical surveillance are reported. Medical surveillance was performed, from the Renam COR Basilicata-Puglia, in favour of 67 workers ex exposed to asbestos of the firm ex-Materit of Ferrandina that produced manufactured articles in cement-asbestos. The actual normative (art 29 DL 277/91) foresees that the competent plant physician informed the workers about the necessities to undergo to sanitary checks after the cessation of the activity, nevertheless the law doesn't establish that whom owes to make load of the medical surveillance. Cor, as Regional Reference Center, like in DPMC 308/2002, can guarantee definition of guide lines for uniform approach to regional level of all the figures involved in the management of the ex-exposed worker problem, in clinician and legal point of view and in the diffusion of the information (general practitioners, physicians operating in prevention services (SPESAL), competent plant physicians, hospital physicians and experts, labour unions).
Published: 2003

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