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1,149 results on '"Cavallaro, S."'

1. An Immunological Algorithm for Graph Modularity Optimization

Author

Spampinato, A. G., Scollo, R. A., Cavallaro, S., Pavone, M., Cutello, V., Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Ju, Zhaojie, editor, Yang, Longzhi, editor, Yang, Chenguang, editor, Gegov, Alexander, editor, and Zhou, Dalin, editor

Published
2020
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2. Dipolar degrees of freedom and Isospin equilibration processes in Heavy Ion collisions

Author

Papa, M., Berceanu, I., Acosta, L., Amorini, F., Agodi, C., Anzalone, A., Auditore, L., Cardella, G., Cavallaro, S., Chatterjee, M. B., De Filippo, E., Francalanza, L., Geraci, E., Grassi, L., Gnoffo, B., Han, J., La Guidara, E., Lanzalone, G., Lombardo, I., Pagano, C. Maiolino T. Minniti A., Pagano, E. V., Pirrone, S., Politi, G., Porto, F., Quattrocchi, L., Rizzo, F., Rosato, E., Russotto, P., Trifirò, A., Trimarchi, M., Verde, G., and Vigilante, M.

Subjects
Nuclear Experiment
Abstract

Background: In heavy ion collision at the Fermi energies Isospin equilibration processes occur- ring when nuclei with different charge/mass asymmetries interacts have been investigated to get information on the nucleon-nucleon Iso-vectorial effective interaction. Purpose: In this paper, for the system 48Ca +27 Al at 40 MeV/nucleon, we investigate on this process by means of an observable tightly linked to isospin equilibration processes and sensitive in exclusive way to the dynamical stage of the collision. From the comparison with dynamical model calculations we want also to obtain information on the Iso-vectorial effective microscopic interaction. Method: The average time derivative of the total dipole associated to the relative motion of all emitted charged particles and fragments has been determined from the measured charges and velocities by using the 4? multi-detector CHIMERA. The average has been determined for semi- peripheral collisions and for different charges Zb of the biggest produced fragment. Experimental evidences collected for the systems 27Al+48Ca and 27Al+40Ca at 40 MeV/nucleon used to support this novel method of investigation are also discussed., Comment: Submitted for publication on Phys. Rev. C. 0n 24-oct-2014

Published
2015
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3. Correlations between emission timescale of fragments and isospin dynamics in $^{124}$Sn+$^{64}$Ni and $^{112}$Sn+$^{58}$Ni reactions at 35 AMeV

Author

De Filippo, E., Pagano, A., Russotto, P., Amorini, F., Anzalone, A., Auditore, L., Baran, V., Berceanu, I., Borderie, B., Bougault, R., Bruno, M., Cap, T., Cardella, G., Cavallaro, S., Chatterjee, M. B., Chbihi, A., Colonna, M., D'Agostino, M., Dayras, R., Di Toro, M., Frankland, J., Galichet, E., Gawlikowicz, W., Geraci, E., Grzeszczuk, A., Guazzoni, P., Kowalski, S., La Guidara, E., Lanzalone, G., Lanzanò, G., Neindre, N. Le, Lombardo, I., Maiolino, C., Papa, M., Piasecki, E., Pirrone, S., Planeta, R., Politi, G., Pop, A., Porto, F., Rivet, M. F., Rizzo, F., Rosato, E., Schmidt, K., Siwek-Wilczynska, K., Skwira-Chalot, I., Trifirò, A., Trimarchi, M., Verde, G., Vigilante, M., Wieleczko, J. P., Wilczynski, J., Zetta, L., and Zipper, W.

Subjects
Nuclear Experiment
Abstract

We present a new experimental method to correlate the isotopic composition of intermediate mass fragments (IMF) emitted at mid-rapidity in semi-peripheral collisions with the emission timescale: IMFs emitted in the early stage of the reaction show larger values of $<$N/Z$>$ isospin asymmetry, stronger angular anisotropies and reduced odd-even staggering effects in neutron to proton ratio $<$N/Z$>$ distributions than those produced in sequential statistical emission. All these effects support the concept of isospin "migration", that is sensitive to the density gradient between participant and quasi-spectator nuclear matter, in the so called neck fragmentation mechanism. By comparing the data to a Stochastic Mean Field (SMF) simulation we show that this method gives valuable constraints on the symmetry energy term of nuclear equation of state at subsaturation densities. An indication emerges for a linear density dependence of the symmetry energy., Comment: 17 pages, 7 figures; submitted to Physical Rev. C

Published
2012
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4. Isospin Dependence of Incomplete Fusion Reactions at 25 Mev/a

Author

Amorini, F., Cardella, G., Giuliani, G., Papa, M., Agodi, C., Alba, R., Anzalone, A., Berceanu, I., Cavallaro, S., Chatterjee, M. B., Coniglione, R., De Filippo, E., Di Pietro, A., Geraci, E., Grassi, L., Grzeszczuk, A., Figuera, P., La Guidara, E., Lanzalone, G., Neindre, N. Le, Lombardo, I., Maiolino, C., Pagano, A., Pirrone, S., Politi, G., Pop, A., Porto, F., Rizzo, F., Russotto, P., Santonocito, D., Sapienza, P., and Verde, G.

Subjects
Nuclear Experiment
Abstract

40Ca+40,48Ca,46Ti reactions at 25 MeV/A have been studied using the 4p CHIMERA detector. An isospin effect on the competition between incomplete fusion and dissipative binary reaction mechanisms has been observed. The probability of producing a compound system is observed to be lower in the case of N=Z colliding systems as compared to the case of reactions induced on the more neutron rich 48Ca target. Predictions based on CoMD-II calculations show that the competition between fusion-like and dissipative reactions, for the selected centrality, can strongly constraint the parameterization of symmetry energy and its density dependence in the nuclear equation of state., Comment: 4 pages 3 figures submitted to phys.rew.Lett

Published
2008
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5. Influence of Chaos on the fusion enhancement by electron screening

Author

Kimura, S., Bonasera, A., and Cavallaro, S.

Subjects
Nuclear Theory
Abstract

We study the effect of screening by bound electrons in low energy nuclear reactions. We use molecular dynamics to simulate the reactions involving many electrons: D+$d$, D+D, $^3$He+$d$, $^3$He+D, $^6$Li+$d$, $^6$Li+D, $^7$Li+$p$, $^7$Li+H. Quantum effects corresponding to the Pauli and Heisenberg principles are enforced by constraints in terms of the phase space occupancy. In addition to the well known adiabatic and sudden limits, we propose a new "dissipative limit" which is expected to be important not only at high energies but in the extremely low energy region. The dissipative limit is associated with the chaotic behavior of the electronic motion. It affects also the magnitude of the enhancement factor. We discuss also numerical experiments using polarized targets. The derived enhancement factors in our simulation are in agreement with those extracted within the $R$-matrix approach., Comment: 6 pages, 6 figures, submitted to The European Physical Journal A (EPJ A direct), Springer-Verlag, in the Proceedings of Nuclear Physics in Astrophysics II, ATOMKI, Debrecen, Hungary, 16-20 May, 2005

Published
2005
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6. Correlation functions and emission time sequence of light charged particles from projectile-like fragment source in E/A = 44 and 77 MeV 40Ar + 27Al collisions

Author

Ghetti, R., Helgesson, J., Lanzano', G., De Filippo, E., Geraci, M., Aiello, S., Cavallaro, S., Pagano, A., Politi, G., Charvet, J. L., Dayras, R., Pollacco, E., Volant, C., Beck, C., Mahboub, D., and Nouicer, R.

Subjects
Nuclear Experiment
Abstract

Two-particle correlation functions, involving protons, deuterons, tritons, and alpha-particles, have been measured at very forward angles (0.7 deg < theta_lab < 7 deg), in order to study projectile-like fragment (PLF) emission in E/A = 44 and 77 MeV 40Ar + 27Al collisions. Peaks, originating from resonance decays, are larger at E/A = 44 than at 77 MeV. This reflects the larger relative importance of independently emitted light particles, as compared to two-particle decay from unstable fragments, at the higher beam energy. The time sequence of the light charged particles, emitted from the PLF, has been deduced from particle-velocity-gated correlation functions (discarding the contribution from resonance decays). Alpha-particles are found to have an average emission time shorter than protons but longer than tritons and deuterons., Comment: 18 pages, 5 figures, submitted to Nuclear Physics A

Published
2004
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7. Possibility to deduce the emission time sequence of neutrons and protons from the neutron-proton correlation function?

Author

Ghetti, R., Helgesson, J., Colonna, N., Jakobsson, B., Anzalone, A., Bellini, V., Carlen, L., Cavallaro, S., Celano, L., De Filippo, E., D'Erasmo, G., Di Santo, D., Fiore, E. M., Fokin, A., Geraci, M., Giustolisi, F., Kuznetsov, A., Lanzano', G., Mahboub, D., Marrone, S., Maartensson, J., Palomba, M., Pantaleo, A., Paticchio, V., Riera, G., Sperduto, M. L., Sutera, C., Tagliente, G., and Urrata, M.

Subjects
Nuclear Experiment
Abstract

Experimental information has been derived from the neutron-proton correlation function in order to deduce the time sequence of neutrons and protons emitted at 45 degrees in the E/A = 45 MeV 58Ni + 27Al reaction., Comment: 4 pages, 4 figures. Physical Review Letters, in press

Published
2001
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8. THE STRONG ROLE OF N/Z DEGREE OF FREEDOM IN Ca plus Ca REACTIONS AT 25 MeV/NUCLEON

Author

Lombardo, I, Agodi, C, Amorini, F, Anzalone, A, Auditore, L, Berceanu, I, Cardella, G, Cavallaro, S, DeFilippo, E, Giuliani, G, Geraci, E, Grassi, L, Han, J, LaGuidara, E, Lanzalone, G, Loria, D, Maiolino, C, Pagano, A, Papa, M, Pirrone, S, Politi, G, Porto, F, Rizzo, F, Russotto, P, Trifiro, A, Trimarchi, M, Verde, G, and Vigilante, M

Subjects
Mathematical Sciences, Physical Sciences, Nuclear & Particles Physics, Mathematical sciences, Physical sciences
Published
2011

9. Multiplicity-free representations of commutative C*-algebras and spectral properties

Author

Cavallaro, S.

Subjects
Mathematics - Operator Algebras
Abstract

Let A be a commutative unital C*-algebra and let S denote its Gelfand spectrum. We give some necessary and sufficient conditions for a nondegenerate representation of A to be unitarily equivalent to a multiplicative representation on a space L^2(S, m), where m is a positive measure on the Baire sets of S. We also compare these conditions with the multiplicity-free property of a representation., Comment: plain-tex

Published
1998

12. Radioactive ion beam opportunities at the new FRAISE facility of INFN-LNS

Author

Martorana, N. S., Cardella, G., Guazzoni, C., Pagano, E. V., Russo, A. D., Russotto, P., Acosta, L., Amato, A., Calabretta, L., Caruso, A., Cavallaro, S., Cosentino, L., Costa, M., De Filippo, E., De Luca, G., Geraci, E., Gnoffo, B., Maiolino, C., Passarello, S., Pirrone, S., Politi, G., Pulvirenti, S., Risitano, F., Rizzo, F., Santonocito, D., Trifiro, A., Trimarchi, M., Tudisco, S., and Vecchio, G.

Subjects
in-flight technique, SiC, unstable nuclei, FRAISE, Materials Science (miscellaneous), Biophysics, General Physics and Astronomy, RIBs, Physical and Theoretical Chemistry, Mathematical Physics
Abstract

At the Laboratori Nazionali del Sud of INFN (INFN-LNS) in Catania, the construction of the new Radioactive Ion Beams (RIBs) facility FRAISE (FRAgment In-flight SEparator) has reached its ending phase. The facility uses the in-flight technique based on a primary beam fragmentation impinging on light Be or C targets. FRAISE makes use of light and medium mass primary beams, having power up to ≈ 2–3 kW, leading to RIBs, whose intensities vary in the range of ≈ 103–107 pps, for nuclei far from and close to the stability valley, respectively. FRAISE aims at providing high-intensity and high-quality RIBs for nuclear physics experiments, also serving to interdisciplinary research areas, such as medical physics. Critical aspects for high-quality beams are the tuning and transport, representing time-consuming processes and requiring dedicated diagnostics and tagging devices measuring many features of RIBs. Some of these devices should be capable to operate in radioactively activated environments because of the expected 2 kW beam lost in the dipole after the production target. Due to its peculiar robustness to radioactive damage, Silicon Carbide (SiC) technology has been considered for the detection layer. In this view, an R&D campaign has been started aiming at developing the FRAISE facility, the new diagnostics system, and a new tagging device, the latter of which will be useful for the CHIMERA multidetector beamline. In this paper, we discuss the status and the perspectives of the facility with a focus on the RIBs opportunities.

Published
2022
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20. Isospin dependence of physical observables in Incomplete Fusion reactions at 25 MeV/nucleon

Author

Lombardo, I., Agodi, C., Alba, R., Amorini, F., Anzalone, A., Berceanu, I., Cardella, G., Cavallaro, S., Chatterjee, M.B., Coniglione, R., DeFilippo, E., DiPietro, A., Figuera, P., Geraci, E., Giuliani, G., Grassi, L., Grzeszczuk, A., LaGuidara, E., Lanzalone, G., LeNeindre, N., Maiolino, C., Pagano, A., Papa, M., Pirrone, S., Politi, G., Pop, A., Porto, F., Rizzo, F., Russotto, P., Santonocito, D., Sapienza, P., and Verde, G.

Published
2010
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23. miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis

Author

Gentile, Giuseppe, Paciello, Fabiola, Zorzi, Veronica, Spampinato, A. G., Guarnaccia, M., Crispino, G., Tettey-Matey, A., Scavizzi, F., Raspa, M., Fetoni, Anna Rita, Cavallaro, S., Mammano, F., Gentile G., Paciello F. (ORCID:0000-0002-8473-8074), Zorzi V., Fetoni A. R. (ORCID:0000-0001-5405-4301), Gentile, Giuseppe, Paciello, Fabiola, Zorzi, Veronica, Spampinato, A. G., Guarnaccia, M., Crispino, G., Tettey-Matey, A., Scavizzi, F., Raspa, M., Fetoni, Anna Rita, Cavallaro, S., Mammano, F., Gentile G., Paciello F. (ORCID:0000-0002-8473-8074), Zorzi V., and Fetoni A. R. (ORCID:0000-0001-5405-4301)

Abstract

Pathogenic mutations in the non-syndromic hearing loss and deafness 1 (DFNB1) locus are the primary cause of monogenic inheritance for prelingual hearing loss. To unravel molecular pathways involved in etiopathology and look for early degeneration biomarkers, we used a system biology approach to analyze Cx30−/− mice at an early cochlear post-natal developmental stage. These mice are a DFNB1 mouse model with severely reduced expression levels of two connexins in the inner ear, Cx30, and Cx26. Integrated analysis of miRNA and mRNA expression profiles in the cochleae of Cx30−/− mice at post-natal day 5 revealed the overexpression of five miRNAs (miR-34c, miR-29b, miR-29c, miR-141, and miR-181a) linked to apoptosis, oxidative stress, and cochlear degeneration, which have Sirt1 as a common target of transcriptional and/or post-transcriptional regulation. In young adult Cx30−/− mice (3 months of age), these alterations culminated with blood barrier disruption in the Stria vascularis (SV), which is known to have the highest aerobic metabolic rate of all cochlear structures and whose microvascular alterations contribute to age-related degeneration and progressive decline of auditory function. Our experimental validation of selected targets links hearing acquisition failure in Cx30−/− mice, early oxidative stress, and metabolic dysregulation to the activation of the Sirt1–p53 axis. This is the first integrated analysis of miRNA and mRNA in the cochlea of the Cx30−/− mouse model, providing evidence that connexin downregulation determines a miRNA-mediated response which leads to chronic exhaustion of cochlear antioxidant defense mechanisms and consequent SV dysfunction. Our analyses support the notion that connexin dysfunction intervenes early on during development, causing vascular damage later on in life. This study identifies also early miRNA-mediated biomarkers of hearing impairment, either inherited or age related.

Published
2021

24. Isospin aspects in nuclear reactions involving Ca beams at 25 MeV/nucleon

Author

Lombardo, I., Agodi, C., Alba, R., Amorini, F., Anzalone, A., Auditore, L., Berceanu, I., Cardella, G., Cavallaro, S., Chatterjee, M. B., De Filippo, E., Di Pietro, A., Figuera, P., Giuliani, G., Geraci, E., Grassi, L., Grzeszczuk, A., Han, J., La Guidara, E., Lanzalone, G., Le Neindre, N., Loria, D., Maiolino, C., Pagano, A., Papa, M., Pirrone, S., Politi, G., Pop, A., Porto, F., Rizzo, F., Russotto, P., Santonocito, D., Trifirò, A., Trimarchi, M., Verde, G., and Vigilante, M.

Published
2011
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26. Multifragmentation threshold in 93Nb + natMg collisions at 30 MeV/nucleon

Author

Manduci, L., Lopez, O., Steckmeyer, J.C., Borderie, B., Bougault, R., Dayras, R., Frankland, J.D., Guinet, D., Lautesse, P., Le Neindre, N., Pârlog, M., Rivet, M.F., Rosato, E., Roy, R., Vient, E., Vigilante, M., Tamain, B., Wieleckzo, J.P., Aiello, S., Anzalone, A., Cardella, G., Cavallaro, S., De Filippo, E., Feminó, S., Giustolisi, F., Guazzoni, P., Lanzalone, G., Lanzanó, G., Nigro, S. Lo, Pagano, A., Papa, M., Pirrone, S., Politi, G., Porto, F., Rizzo, F., Sperduto, L., and Zetta, L.

Published
2008
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30. Digital signal processing for mass identification in a 4[pi]--detector, using time of flight measurement

Author

Amorini, F., Anzalone, A., Bassini, R., Boiano, C., Cardella, G., Cavallaro, S., De Filippo, E., Guazzoni, P., La Guidara, E., Lanzano, G., Pagano, A., Papa, M., Pirrone, S., Politi, G., Porto, F., Riccio, F., Rizzo, F., Russo, S., Russotto, P., and Zetta, L.

Subjects
Algorithms -- Methods, Signal processing -- Methods, Radiation warning systems -- Properties, Radiation -- Measurement, Radiation -- Methods, Algorithm, Digital signal processor, Business, Electronics, Electronics and electrical industries
Abstract

CHIMERA is the only 4[pi]-multidetector, used in intermediate nuclear physics experiments, able to perform mass identification of the reaction products. To this purpose, it employs time of flight measurements done with traditional time to digital converters. In order to improve the resolution in mass identification, we have applied digital signal processing to time of flight measurements. This paper presents the methodology for data analysis, the adopted algorithms and the results obtained at different sampling frequencies (mass identification up to A = 33 for the reaction products produced by a 20.5 MeV/u [sup.20]Ne beam on [sup.27]Al target). Index Terms--Mass identification, nuclear measurements, nuclear physics, online digital signal processing, time of flight measurement.

Published
2008

31. On-board digital signal processing for 4 [pi]-detector large-area telescopes

Author

Amorini, F., Anzalone, A., Cardella, G., Cavallaro, S., De Filippo, E., Guazzoni, P., La Guidara, E., Lanzano, G., Pagano, A., Pirrone, S., Politi, G., Porto, F., Riccio, F., Rizzo, F., Russo, S., Russotto, P., and Zetta, L.

Subjects
Digital signal processors -- Research, Nuclear physics -- Research, Telescope -- Research, Digital signal processor, Business, Electronics, Electronics and electrical industries
Abstract

The digital pulse shape data acquisition (DAQ) system used by the large area telescopes of the 4[pi]-multidetector CHIMERA requires transferring large amount of data to the computer. This is necessary so that the same information can be extracted from the detector pulses as in previous analog based systems. To overcome this problem, we have used a sampling ADC-board equipped with two TigerSHARC digital signal processors. The board receives the data and reconstructs the event parameters online. The data volume is significantly reduced by transmitting to the DAQ only the reconstructed event parameters. Index Terms--Digital signal processors, mass and charge identification, nuclear measurements, nuclear physics, online and on-board digital signal processing.

Published
2007

33. Charge identification in large area planar silicon detectors, using digital pulse shape acquisition

Author

Alderighi, M., Amorini, F., Anzalone, A., Bassini, R., Boiano, C., Cardella, G., Cavallaro, S., DeFilippo, E., Guazzoni, P., LaGuidara, E., Lanzano, G., Lanzalone, G., Maiolino, C., Pagano, A., Papa, M., Pirrone, S., Politi, G., Porto, F., Rizzo, F., Russo, S., Sacca, G., Sassi, M., Sechi, G., and Zetta, L.

Subjects
Silicon diodes -- Mechanical properties, Silicon diodes -- Observations, Electric charge and distribution -- Observations, Business, Electronics, Electronics and electrical industries
Abstract

The capability of digital pulse shape technique to acquire data from CHIMERA detection cells (Si-CsI(TI) telescopes) has been evidenced in our previous works. We have now applied this technique to the charge discrimination of the products stopped in the silicon detectors. Large area totally depleted CHIMERA planar silicon detectors (5 cm x 5 cm area, 300/[micro]m thick) in both rear and front side injection have been used. In preliminary tests full charge identification for the reaction products up to Z = 11 have been obtained for products both crossing ([DELTA]E-E technique) and stopping in the silicon detector, using a 21 MeV/u [sup.20]Ne beam at the LNS Superconducting Cyclotron in Catania. The quality of the obtained results clearly indicates that the digital signal processing approach is able to give excellent results in this application, too. Index Terms--Charged particle identification, digital pulse shape processing, multidetector arrays technique, pulse shape analysis.

Published
2006

34. PRESTO: a computational and storage unit for CHIMERA DAQ

Author

Alderighi, M., Amorini, F., Anzalone, A., Cardella, G., Cavallaro, S., DeFilippo, E., Ghilardi, D., Guazzoni, P., LaGuidara, E., Lanzano, G., Lanzalone, G., Maiolino, C., Pagano, A., Papa, M., Pirrone, S., Politi, G., Porto, F., Rizzo, F., Russo, S., Russotto, P., Santonocito, D., Sassi, M., Sechi, G.R., and Zetta, L.

Subjects
Information storage and retrieval -- Research, Computers -- Services, Computers -- Management, Data acquisition software, Company business management, Business, Electronics, Electronics and electrical industries
Abstract

We have designed, built, and tested an on-line pre-analysis and data-storage unit for the data acquisition system of the 47r-detector CHIMERA. The unit uses special algorithms to perform particle identification and automatic peak detection. It tags in charge each event and stores the results on external unit, together with the raw data. It consists of two commercial 2 GHz workstations connected together through 1 Gb/s Ethernet boards and to the data acquisition system through a 100 Mb/s Ethernet. Index Terms--Data storage unit, multidetector online monitoring, online computational system.

Published
2005

35. Particle identification via pulse shape analysis for large-area silicon detectors of the CHIMERA array

Author

Alderighi, M., Amorini, F., Anzalone, A., Arena, N., Auditore, L., Bassini, R., Boiano, C., Cardella, G., Cavallaro, S., Chatterjee, M.B., D'Andrea, M., De Filippo, E., Fichera, F., Geraci, E., Giustolisi, F., Guardone, N., Grimaldi, A., Guazzoni, P., La Guidara, E., Lanzano, G., Lanzalone, G., Maiolino, C., Nicotra, D., Pagano, A., Papa, M., Pirrone, S., Politi, G., Porto, F., Pullia, A., Rizzo, F., Russo, S., Russotto, P., Santonocito, D., Sacca, G., Sassi, M., Schroder, W. Udo, Sechi, G.R., Trifiro, A., Toke, J., Trimarchi, M., Urso, S., and Zetta, L.

Subjects
Silicon diodes -- Design and construction, Business, Electronics, Electronics and electrical industries
Abstract

Mass and atomic-number identification (ID) of reaction products is a fundamental requirement of any nuclear reaction study. An effective particle-ID method is demonstrated, based on pulse shape analysis/discrimination (PSD) applied to large-area, single-element silicon detectors. This technique uses commercial electronic modules and achieves atomic number resolution rivaling that typically obtained with multi-element ([DELTA]E-E) detector telescopes. The method is applied to the CHIMERA detector system without compromising its time-of-flight (TOF) resolution. In-beam tests of the PSD method have been performed with large-area, 300-[micro]m thick CHIMERA silicon detectors, measuring particles from the [sup.19]F + [sup.12]C reaction at Tandem energies. Performance of a simple PSD set up is discussed, for front and rear particle injection. Index Terms--Charge identification, planar silicon detector, pulse shape.

Published
2005

36. CHIMERA data acquisition via digital sampling technique

Author

Alderighi, M., Anzalone, A., Bassini, R., Boiano, C., Cardella, G., Cavallaro, S., De Filippo, E., Geraci, E., Giustolisi, F., Guazzoni, P., Laguidara, E., Lanzano, G., Lanzalone, G., Pagano, A., Papa, M., Pirrone, S., Politi, G., Porto, F., Russo, S., Sassi, M., Sechi, G.R., and Zetta, L.

Subjects
Sampling (Acoustical engineering) -- Methods, Detectors -- Analysis, Data entry, Business, Electronics, Electronics and electrical industries
Abstract

A 100 Msamples/s 14-bit sampling analog-to-digital converter has been used to perform digital pulse-shape acquisition of signals collected from CHIMERA telescopes. Two different kinds of tests have been carried out to check the performances. The signals from a typical CHIMERA detection cell have been collected using both a standard CHIMERA electronic chain up to the amplifier, and a very simple analog front end, basically reduced to the preamplifier. The obtained on-beam and on-line results are presented. Index Terms--Digital pulse shape acquisition, digital signal processing, multidetector arrays, particle identification, simple analog front end.

Published
2004

39. D-D nuclear fusion processes induced in polyethylene foams by TW Laser-generated plasma

Author

Torrisi L., Cutroneo M., Cavallaro S., and Ullschmied J.

Subjects
Physics, QC1-999
Abstract

Deuterium-Deuterium fusion processes were generated by focusing the 3 TW PALS Laser on solid deuterated polyethylene targets placed in vacuum. Deuterium ion acceleration of the order of 4 MeV was obtained using laser irradiance Iλ2 ∼ 5 × 1016 W μm2/cm2 on the target. Thin and thick targets, at low and high density, were irradiated and plasma properties were monitored “on line” and “off line”. The ion emission from plasma was monitored with Thomson Parabola Spectrometer, track detectors and ion collectors. Fast semiconductor detectors based on SiC and fast plastic scintillators, both employed in time-of-flight configuration, have permitted to detect the characteristic 3.0 MeV protons and 2.45 MeV neutrons emission from the nuclear fusion reactions. From massive absorbent targets we have evaluated the neutron flux by varying from negligible values up to about 5 × 107 neutrons per laser shot in the case of foams targets, indicating a reaction rate of the order of 108 fusion events per laser shot using “advanced targets”.

Published
2015
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48. Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis

Author

Bandres‐Ciga, S, Noyce, AJ, Hemani, G, Nicolas, A, Calvo, A, Mora, G, Arosio, A, Barberis, M, Bartolomei, I, Battistini, S, Benigni, M, Borghero, G, Brunetti, M, Cammarosano, S, Cannas, A, Canosa, A, Capasso, M, Caponnetto, C, Caredda, C, Carrera, P, Casale, F, Cavallaro, S, Chiò, A, Colletti, T, Conforti, FL, Conte, A, Corrado, L, Costantino, E, D'Alfonso, S, Fasano, A, Femiano, C, Ferrarese, C, Fini, N, Floris, G, Fuda, G, Giannini, F, Grassano, M, Ilardi, A, La Bella, V, Lattante, S, Logroscino, G, Logullo, FO, Loi, D, Lunetta, C, Mancardi, G, Mandich, P, Mandrioli, J, Manera, U, Marangi, G, Marinou, K, Marrali, G, Marrosu, MG, Mazzini, L, Melis, M, Messina, S, Moglia, C, Monsurro, MR, Mosca, L, Occhineri, P, Origone, P, Pani, C, Penco, S, Petrucci, A, Piccirillo, G, Pirisi, A, Pisano, F, Pugliatti, M, Restagno, G, Ricci, C, Rita Murru, M, Riva, N, Sabatelli, M, Salvi, F, Santarelli, M, Sideri, R, Simone, I, Spataro, R, Tanel, R, Tedeschi, G, Tranquilli, S, Tremolizzo, L, Trojsi, F, Volanti, P, Zollino, M, Abramzon, Y, Arepalli, S, Baloh, RH, Bowser, R, Brady, CB, Brice, A, Broach, J, Campbell, RH, Camu, W, Chia, R, Cooper‐Knock, J, Cusi, D, Ding, J, Drepper, C, Drory, VE, Dunckley, TL, Eicher, JD, Faghri, F, Feldman, E, Kay Floeter, M, Fratta, P, Geiger, JT, Gerhard, G, Gibbs, JR, Gibson, SB, Glass, JD, Hardy, J, Harms, MB, Heiman‐Patterson, TD, Hernandez, DG, Jansson, L, Kamel, F, Kirby, J, Kowall, NW, Laaksovirta, H, Landi, F, Le Ber, I, Lumbroso, S, MacGowan, DJL, Maragakis, NJ, Mouzat, K, Murphy, NA, Myllykangas, L, Nalls, MA, Orrell, RW, Ostrow, LW, Pamphlett, R, Pickering‐Brown, S, Pioro, E, Pliner, HA, Pulst, SM, Ravits, JM, Renton, AE, Rivera, A, Robbrecht, W, Rogaeva, E, Rollinson, S, Rothstein, JD, Salvi, E, Scholz, SW, Sendtner, M, Shaw, PJ, Sidle, KC, Simmons, Z, Singleton, AB, Stone, DC, Sulkava, R, Tienari, PJ, Traynor, BJ, Trojanowski, JQ, Troncoso, JC, Van Damme, P, Van Deerlin, VM, Van Den Bosch, L, Zinman, L, Stone, DJ, Bandres-Ciga, Sara, Noyce, Alastair J., Hemani, Gibran, Nicolas, Aude, Calvo, Andrea, Mora, Gabriele, Arosio, Alessandro, Barberis, Marco, Bartolomei, Ilaria, Battistini, Stefania, Benigni, Michele, Borghero, Giuseppe, Brunetti, Maura, Cammarosano, Stefania, Cannas, Antonino, Canosa, Antonio, Capasso, Margherita, Caponnetto, Claudia, Caredda, Carla, Carrera, Paola, Casale, Federico, Cavallaro, Sebastiano, Chiò, Adriano, Colletti, Tiziana, Conforti, Francesca L., Conte, Amelia, Corrado, Lucia, Costantino, Emanuela, D'Alfonso, Sandra, Fasano, Antonio, Femiano, Cinzia, Ferrarese, Carlo, Fini, Nicola, Floris, Gianluca, Fuda, Giuseppe, Giannini, Fabio, Grassano, Maurizio, Ilardi, Antonio, La Bella, Vincenzo, Lattante, Serena, Logroscino, Giancarlo, Logullo, Francesco O., Loi, Daniela, Lunetta, Christian, Mancardi, Gianluigi, Mandich, Paola, Mandrioli, Jessica, Manera, Umberto, Marangi, Giuseppe, Marinou, Kalliopi, Marrali, Giuseppe, Marrosu, Maria Giovanna, Mazzini, Letizia, Melis, Maurizio, Messina, Sonia, Moglia, Cristina, Monsurro, Maria Rosaria, Mosca, Lorena, Occhineri, Patrizia, Origone, Paola, Pani, Carla, Penco, Silvana, Petrucci, Antonio, Piccirillo, Giovanni, Pirisi, Angelo, Pisano, Fabrizio, Pugliatti, Maura, Restagno, Gabriella, Ricci, Claudia, Rita Murru, Maria, Riva, Nilo, Sabatelli, Mario, Salvi, Fabrizio, Santarelli, Marialuisa, Sideri, Riccardo, Simone, Isabella, Spataro, Rossella, Tanel, Raffaella, Tedeschi, Gioacchino, Tranquilli, Stefania, Tremolizzo, Lucio, Trojsi, Francesca, Volanti, Paolo, Zollino, Marcella, Abramzon, Yevgeniya, Arepalli, Sampath, Baloh, Robert H., Bowser, Robert, Brady, Christopher B., Brice, Alexi, Broach, Jame, Campbell, Roy H., Camu, William, Chia, Ruth, Cooper-Knock, John, Cusi, Daniele, Ding, Jinhui, Drepper, Carsten, Drory, Vivian E., Dunckley, Travis L., Eicher, John D., Faghri, Faraz, Feldman, Eva, Kay Floeter, Mary, Fratta, Pietro, Geiger, Joshua T., Gerhard, Glenn, Gibbs, J. Raphael, Gibson, Summer B., Glass, Jonathan D., Hardy, John, Harms, Matthew B., Heiman-Patterson, Terry D., Hernandez, Dena G., Jansson, Lilja, Kamel, Freya, Kirby, Janine, Kowall, Neil W., Laaksovirta, Hannu, Landi, Francesco, Le Ber, Isabelle, Lumbroso, Serge, Macgowan, Daniel J. L., Maragakis, Nicholas J., Mouzat, Kevin, Murphy, Natalie A., Myllykangas, Liisa, Nalls, Mike A., Orrell, Richard W., Ostrow, Lyle W., Pamphlett, Roger, Pickering-Brown, Stuart, Pioro, Erik, Pliner, Hannah A., Pulst, Stefan M., Ravits, John M., Renton, Alan E., Rivera, Alberto, Robbrecht, Wim, Rogaeva, Ekaterina, Rollinson, Sara, Rothstein, Jeffrey D., Salvi, Erika, Scholz, Sonja W., Sendtner, Michael, Shaw, Pamela J., Sidle, Katie C., Simmons, Zachary, Singleton, Andrew B., Stone, David C., Sulkava, Raimo, Tienari, Pentti J., Traynor, Bryan J., Trojanowski, John Q., Troncoso, Juan C., Van Damme, Philip, Van Deerlin, Vivianna M., Van Den Bosch, Ludo, Zinman, Lorne, Stone, David J., Van Damme, P, Bandres-Ciga, S, Noyce, A, Hemani, G, Nicolas, A, Calvo, A, Mora, G, Tienari, P, Stone, D, Nalls, M, Singleton, A, Chiò, A, Traynor, Bryan, J, Tremolizzo, L, Department of Neurosciences, Neurologian yksikkö, Clinicum, HUS Neurocenter, Translational neuroradiology unit [Bethesda], National Institute of Neurological Disorders and Stroke [Bethesda] (NINDS), National Institutes of Health [Bethesda] (NIH)-National Institutes of Health [Bethesda] (NIH), Univ Granada, Hosp Univ Granada, Inst Invest Biosanitaria Ibs GRANADA, Escuela Andaluza Salud Publ, Granada, Spain, Partenaires INRAE, Queen Mary University of London (QMUL), University College of London [London] (UCL), University of Bristol [Bristol], Département de Physique, Université de Genève, Université de Genève (UNIGE), Università degli studi di Torino (UNITO), University G. d'Annunzio, Chieti, Università degli studi 'G. d'Annunzio' Chieti-Pescara [Chieti-Pescara] (Ud'A), Department of Neurology, A.O.U. Maggiore della Carità, and IRCAD, Novara, Department of Health Sciences, UPO University, UPO University, Dipartimento di Matematica 'Ulisse Dini', Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Department of Neurology, Università degli Studi di Milano-Bicocca [Milano] (UNIMIB), Department of Neuroscience, University of Siena, Siena, Università cattolica del Sacro Cuore [Roma] (Unicatt), Università degli studi di Bari Aldo Moro (UNIBA), Istituto di Genetica Medica, Centro Sclerosi Multipla, Ospedale Binaghi, Via Is Guadazzonis 2, Cagliari, Italy, University of Novara, IRCCS-Istituti Clinici Scientifici Maugeri, University of Milan, Milan, Italy, Department of Biomedical and Specialty Surgical Sciences, Università degli Studi di Ferrara (UniFE), S. Anna Hospital, Department of Neuroscience, Catholic University, Roma, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Institute of Medical Genetics, Catholic University, Rome, Italy, Department of Clinical Genetics, Department of Pathology University of Pittsburgh School of Medicine, Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière (CRICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Princeton University, University of Illinois at Urbana-Champaign [Urbana], University of Illinois System, Centre référent Sclérose Latérale Amyotrophique [CHRU Montpellier] (SLA CHRU Montpellier), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Università degli Studi di Milano [Milano] (UNIMI), Laboratory of Neurogenetics, National Institute of Aging, Tel Aviv Sourasky Medical Center [Te Aviv], University of New Haven [Connecticut], Emory University [Atlanta, GA], UCL Institute of neurology, UCL Institute of Neurology, Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca, Genomic Research Laboratory, Service of Infectious Disease, Hôpitaux Universitaires de Genève (HUG), Boston University [Boston] (BU), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire de Biochimie [CHRU Nîmes], Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, University of California [Davis] (UC Davis), University of California-University of California, Tanz Center Research in Neurodegenerative Diseases [Toronto], University of Toronto, Johns Hopkins University, School of Medicine, Department of Medicine, Surgery, and Dentistry, University of Milano, Institute for Clinical Neurobiology, Julius-Maximilians-Universität Würzburg [Wurtzbourg, Allemagne] (JMU), Penn State Hershey Medical Center, Penn State Health Milton S. Hershey Medical Center, Pennsylvania Commonwealth System of Higher Education (PCSHE)-Penn State System-Pennsylvania Commonwealth System of Higher Education (PCSHE)-Penn State System, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Perelman School of Medicine, University of Pennsylvania [Philadelphia], Metacohorts Consortium, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), University of Helsinki, Merck Research Laboratories, National Institutes of Health [Bethesda] (NIH), Center for Neuroscience and Regenerative Medicine [Bethesda] (CNRM), and Henry M. Jackson Foundation for the Advancement of Military Medicine (HJM)

Subjects
0301 basic medicine, Linkage disequilibrium, Multifactorial Inheritance, Multivariate analysis, LD SCORE REGRESSION, DYSLIPIDEMIA, Genome-wide association study, 3124 Neurology and psychiatry, 0302 clinical medicine, PROTECTIVE FACTOR, Mendelian Randomization Analysis, 3. Good health, ALZHEIMERS-DISEASE, Settore MED/26 - NEUROLOGIA, risk factor, BIAS, Neurology, CARDIOVASCULAR-DISEASE, MENDELIAN RANDOMIZATION, Amyotrophic lateral Sclerosis, LD score regression, Mendelian randomization, amyotrophic lateral sclerosis, public resource, Life Sciences & Biomedicine, Clinical psychology, Human, Clinical Neurology, Biology, NO, 03 medical and health sciences, Humans, Genetic Predisposition to Disease, Mendelian Randomization Analysi, MESH: Amyotrophic Lateral Sclerosis, Genetic Predisposition to Disease / genetics, Genome-Wide Association Study / methods, Mendolian Randomization Analysis / methods, Exercise, Genetic association, Science & Technology, [SCCO.NEUR]Cognitive science/Neuroscience, Amyotrophic Lateral Sclerosis, 3112 Neurosciences, Neurosciences, 030104 developmental biology, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, CHOLESTEROL HOMEOSTASIS, Causal inference, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Neurosciences & Neurology, Neurology (clinical), Genome-Wide Association Study, ALS, 030217 neurology & neurosurgery, Amyotrophic Lateral Sclerosi
Abstract

OBJECTIVE: To identify shared polygenic risk and causal associations in amyotrophic lateral sclerosis (ALS). METHODS: Linkage disequilibrium score regression and Mendelian randomization were applied in a large-scale, data-driven manner to explore genetic correlations and causal relationships between >700 phenotypic traits and ALS. Exposures consisted of publicly available genome-wide association studies (GWASes) summary statistics from MR Base and LD-hub. The outcome data came from the recently published ALS GWAS involving 20,806 cases and 59,804 controls. Multivariate analyses, genetic risk profiling, and Bayesian colocalization analyses were also performed. RESULTS: We have shown, by linkage disequilibrium score regression, that ALS shares polygenic risk genetic factors with a number of traits and conditions, including positive correlations with smoking status and moderate levels of physical activity, and negative correlations with higher cognitive performance, higher educational attainment, and light levels of physical activity. Using Mendelian randomization, we found evidence that hyperlipidemia is a causal risk factor for ALS and localized putative functional signals within loci of interest. INTERPRETATION: Here, we have developed a public resource (https://lng-nia.shinyapps.io/mrshiny) which we hope will become a valuable tool for the ALS community, and that will be expanded and updated as new data become available. Shared polygenic risk exists between ALS and educational attainment, physical activity, smoking, and tenseness/restlessness. We also found evidence that elevated low-desnity lipoprotein cholesterol is a causal risk factor for ALS. Future randomized controlled trials should be considered as a proof of causality. Ann Neurol 2019;85:470-481. ispartof: ANNALS OF NEUROLOGY vol:85 issue:4 pages:470-481 ispartof: location:United States status: published

Published
2019
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49. The data acquisition and control system for the 4 pi detector CHIMERA

Author

Aiello, S., Anzalone, A., Cardella, G., Cavallaro, S., De Filippo, E., Femino, S., Geraci, M., Giustolisi, F., Guazzoni, P., Iacono-Manno, C.M., Lanzalone, G., Lanzano, G., Lo Nigro, S., Pagano, A., Papa, M., Pirrone, S., Politi, G., Porto, F., Rizzo, F., Sambataro, S., Sperduto, M.L., Sutera, C.M., and Zetta, L.

Subjects
Real-time data processing -- Analysis, Automatic data collection systems -- Analysis, Control systems -- Analysis, Heavy ions -- Information management, Business, Electronics, Electronics and electrical industries
Abstract

CHIMERA (Charged Heavy Ions Mass and Energy Resolving Army), a new 4[Pi] detector for charged particles is under development at various sites of the Istituto Nazionale di Fisica Nucleate. This paper describes the new data acquisition system built to handle the signals coming out from the detector with a rate up to 1 kHz on almost 5000 electronic channels. The required average throughput for the system is in the order of the 1 MB/s. The used converters allow double-range conversion on 15 bits, in less than 50 [[micro]second] for all the 64 channels. The FDL link connects the different VME 9U crates performing a programmable hardware readout with a rate up to 100 MB/s. It uses a fast hardware protocol (Sparse Data Scan) to read the data buffers and send them to a FIC 8243 CPU board. A FIC 8243 dual-processor board forwards data (through Ethernet) to the analysis station (266Mhz Digital AlphaStation or Sun Sparcstation). A DLT (Digital Linear Tape) unit connected to analysis station is used to store data. The new data acquisition system has been tested under beam conditions at the Laboratorio Nazionale del Sud (Catania, Italy) and at GANIL (Caen, France).

Published
1998

50. Detector array control and triggering

Author

Aiello, S., Anzalone, A., Bartolucci, M., Cardella, G., Cavallaro, S., De Filippo, E., Femino, S., Geraci, M., Giustolisi, F., Guazzani, P., Iacono Manno, M., Lanzalone, G., Lanzano, G., LoNigro, S., Manfredi, G., Pagano, A., Papa, M., Pirrone, S., Politi, G., Porto, F., Rizzo, F., Sambataro, S., Sperduto, L., Sutera, C., and Zetta, L.

Subjects
Nuclear counters -- Research, Array processors -- Research, Trigger circuits -- Research, Real-time data processing -- Research, Real-time systems -- Research, Business, Electronics, Electronics and electrical industries
Abstract

A commercial DSP-based board installed in a host-PC was employed for the fast, on-line and real-time computation of special algorithms, in order to perform event selection and operate as a 2nd level trigger. Moreover an ad hoc built interface, realized using PLDs with a view to connecting the DSP-board to the ADCs and to the data acquisition system, has been tested in order to evaluate the performances of these programmable devices used as a look-up-table and as a decisional part of a 1st level trigger.

Published
1998

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