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80% of leukemias in adults present as the acute myeloid leukemia (AML) form. Many different types of skin lesion can be seen in the course of leukemias. Most of them are benign lesions resulting from chemotherapeutic drug reactions, infectious complications due to immunosuppression, cytopenias or hemorrhagic diathesis. Leukemia cutis (LC) are rare lesions of the skin showing infiltration of malignant cells. The diagnosis of LC is often made with or after the diagnosis of systemic leukemia. In this study we discuss a patient who was admitted to the emergency department because of skin rashes and was diagnosed with AML. LC was detected in this patient after a follow-up biopsy of skin lesions [ABSTRACT FROM AUTHOR]

Background: Cytogenetic findings are important prognostic factors in acute myeloid leukemia. Large systematic data about chromosomal characteristics of Turkish AML patients have not been reported to date., Objectives: The karyotypic profiles of 157 adult AML patients were evaluated retrospectively and compared with other reports from different populations., Methods: Cytogenetics analyses were performed on bone marrow samples using G-banding. Patients were categorized according to their cytogenetic results into four groups with the addition of a normal karyotyped group to the favorable, intermediate and adverse groups of European Leukemia Network., Results: Cytogenetic analyses were carried out successfully in 138 patients (88%). Abnormal karyotypes were found in 79 (57.2%) patients of which 13 (9.4%) were in favorable, 37 (26.8%) in intermediate and 29 (21%) in adverse groups. t(8;21) (5%) was the most common favorable abnormality while monosomal karyotypes (15.9%) in adverse group., Conclusion: This single center study is the most comprehensive study about the cytogenetic profile of acute myeloid leukemia in Turkey with comparison of other population-based studies. While there were similarities and differences with different publications, our results did not show a marked tendency to the findings of any specific geographic region., (© 2022 Cirakoglu A et al.)

Bronchus Associated Lymphoid Tissue Lymphoma (BALTOMA) is a rare subgroup of pulmonary non-Hodgkin's lymphomas (NHLs) comprising less than 1% of all cases. It constitutes 3.6% of all extranodal lymphomas and only 0.5-1% of primary pulmonary malignancies. They are usually low grade B-cell lymphomas and are considered to originate from the mucosa associated lymphoid tissue (MALT) of the bronchi. Here, we represent a rare case of BALTOMA presenting with immunodeficiency and multiple pulmonary nodules.