32 results on '"Chacko, Silvi A."'
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2. The Current Status and Use of Microphysiological Systems by the Pharmaceutical Industry: The IQ Microphysiological Systems Affiliate Survey and Commentary
3. Discovery of BMS-986308: A Renal Outer Medullary Potassium Channel Inhibitor for the Treatment of Heart Failure
4. The Current Status and Use of Microphysiological Systems by the Pharmaceutical Industry: The International Consortium for Innovation and Quality Microphysiological Systems Affiliate Survey and Commentary
5. 2-Pyridine Carboxaldehyde for Semi-Automated Soft Spot Identification in Cyclic Peptides
6. Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy
7. Preclinical metabolism and disposition of an orally bioavailable macrocyclic FXIa inhibitor
8. Azatricyclic Inverse Agonists of RORγt That Demonstrate Efficacy in Models of Rheumatoid Arthritis and Psoriasis
9. Tricyclic sulfones as potent, selective and efficacious RORγt inverse agonists – Exploring C6 and C8 SAR using late-stage functionalization
10. In situ generation of HCN for mass spectrometric studies
11. Dissociation of chloride from ortho-, meta- and para-chloromethylphenoxides: The enthalpy of formation of meta-quinomethane
12. Deoxygenation of sulfoxides, selenoxides, telluroxides, sulfones, selenones and tellurones with Mg–MeOH
13. Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species
14. Hepatocyte spheroids as a viable in vitro model for recapitulation of complex in vivo metabolism pathways of loratadine in humans
15. Identification and characterisation of a novel amino acid conjugate; ergothioneine conjugate of raloxifene through in vitroand in vivostudies
16. Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)
17. Hepatocyte spheroids as a viable in vitro model for recapitulation of complex in vivo metabolism pathways of loratadine in humans.
18. Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)
19. Studies of the electron-promoted Cope cyclization of 2,5-phenyl-substituted 1,5-hexadiene radical anions
20. Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y1 antagonist as an antiplatelet agent
21. Absolute quantification of imipramine and its metabolites in vivo utilizing calibrators from radiolabeled in vitro incubations
22. 4-Benzothiazole-7-hydroxyindolinyl Diaryl Ureas Are Potent P2Y1Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution
23. Hybrid Mass Analyzers in Drug Metabolism Applications
24. On the inter-instrument and the inter-laboratory transferability of a tandem mass spectral reference library. 3. Focus on ion trap and upfront CID
25. Deoxygenation of Sulfoxides, Selenoxides, Telluroxides, Sulfones, Selenones and Tellurones with Mg—MeOH.
26. 4-Benzothiazole-7-hydroxyindolinyl Diaryl Ureas Are Potent P2Y1 Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution.
27. Studies of the Electron-Promoted Cope Cyclization of 2,5-Phenyl-Substituted 1,5-Hexadiene Radical Anions
28. The Negative Ion Chemistry of Nitric Oxide in the Gas Phase
29. The negative ion chemistry of nitric oxide in the gas phase
30. The negative ion chemistry of nitric oxide in the gas phase.
31. Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y1 antagonist as an antiplatelet agent.
32. 4-Benzothiazole-7-hydroxyindolinyl diaryl ureas are potent P2Y1 antagonists with favorable pharmacokinetics: low clearance and small volume of distribution.
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