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353 results on '"Chaim, Elinton Adami"'

2. Diving into the proteomic atlas of SARS-CoV-2 infected cells

Author

Carregari, Victor C., Reis-de-Oliveira, Guilherme, Crunfli, Fernanda, Smith, Bradley J., de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Saia-Cereda, Veronica M., Vendramini, Pedro H., Baldasso, Paulo A., Silva-Costa, Lícia C., Zuccoli, Giuliana S., Brandão-Teles, Caroline, Antunes, André, Valença, Aline F., Davanzo, Gustavo G., Virgillio-da-Silva, João Victor, dos Reis Araújo, Thiago, Guimarães, Raphael Campos, Chaim, Felipe David Mendonça, Chaim, Elinton Adami, Kawagosi Onodera, Carolina Mie, Ludwig, Raissa Guimarães, Saccon, Tatiana Dandolini, Damásio, André R. L., Leiria, Luiz Osório S., Vinolo, Marco Aurélio R., Farias, Alessandro S., Moraes-Vieira, Pedro M., Mori, Marcelo A., Módena, José Luiz P., and Martins-de-Souza, Daniel

Published
2024
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12. SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner

Author

Saccon, Tatiana Dandolini, Mousovich-Neto, Felippe, Ludwig, Raissa Guimarães, Carregari, Victor Corasolla, dos Anjos Souza, Ana Beatriz, dos Passos, Amanda Stephane Cruz, Martini, Matheus Cavalheiro, Barbosa, Priscilla Paschoal, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Forato, Julia, Amorim, Mariene Ribeiro, Marques, Rafael Elias, Veras, Flavio Protasio, Barreto, Ester, Gonçalves, Tiago Tomazini, Paiva, Isadora Marques, Fazolini, Narayana P. B., Onodera, Carolina Mie Kawagosi, Martins Junior, Ronaldo Bragança, de Araújo, Paulo Henrique Cavalcanti, Batah, Sabrina Setembre, Viana, Rosa Maria Mendes, de Melo, Danilo Machado, Fabro, Alexandre Todorovic, Arruda, Eurico, Queiroz Cunha, Fernando, Cunha, Thiago Mattar, Pretti, Marco Antônio M., Smith, Bradley Joseph, Marques-Souza, Henrique, Knittel, Thiago L., Ruiz, Gabriel Palermo, Profeta, Gerson S., Fontes-Cal, Tereza Cristina Minto, Boroni, Mariana, Vinolo, Marco Aurélio Ramirez, Farias, Alessandro S., Moraes-Vieira, Pedro Manoel M., Bizzacchi, Joyce Maria Annichino, Teesalu, Tambet, Chaim, Felipe David Mendonça, Cazzo, Everton, Chaim, Elinton Adami, Proença-Módena, José Luiz, Martins-de-Souza, Daniel, Osako, Mariana Kiomy, Leiria, Luiz Osório, and Mori, Marcelo A.

Published
2022
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14. Impact of pre-operative weight loss on non-alcoholic fatty liver disease histopathology and insulin resistance in individuals undergoing bariatric surgery: a propensity matched cross-sectional comparison

Author

Maldonado, Fábio Henrique Ribeiro, primary, Mega, Paulo Ferreira, additional, Germano, Carlos Wustemberg, additional, Dias, Luana Leite Castilho, additional, Callejas, Guilherme Hoverter, additional, Gestic, Martinho Antonio, additional, Utrini, Murillo Pimentel, additional, Chaim, Felipe David Mendonça, additional, Callejas-Neto, Francisco, additional, Chaim, Elinton Adami, additional, and Cazzo, Everton, additional

Published
2024
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21. O ABUSO SEXUAL COMO CAUSA EMOCIONAL DA OBESIDADE

Author

Almeida, Ana Maria Neder de, primary, Poletto, Jéssica Eloá, additional, Cândido, Elaine Cristina, additional, Chaim, Felipe David Mendonça, additional, Santo, Rogério Terra do Espírito, additional, Gestic, Martinho Antonio, additional, Utrini, Murillo Pimentel, additional, Braga, João Gabriel Romero, additional, Cazzo, Everton, additional, and Chaim, Elinton Adami, additional

Published
2020
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23. Fibrotic NASH in Individuals with Obesity: a Cross-sectional Analysis of the Prevalence of this Significant Milestone of Disease Progression and Accuracy of a Non-invasive Marker for its Screening.

Author

de Souza Echeverria, Luísa, Mounzer, Daniel Leandro Saran, Gestic, Martinho Antonio, Utrini, Murillo Pimentel, Chaim, Felipe David Mendonça, Callejas-Neto, Francisco, Chaim, Elinton Adami, and Cazzo, Everton

Subjects
DISEASE progression, MEDICAL screening, CROSS-sectional method, MORBID obesity, LIVER histology, NON-alcoholic fatty liver disease, BARIATRIC surgery, FATTY liver
Abstract

Background: Fibrotic non-alcoholic steatohepatitis (NASH), i.e., the concomitant presence of active inflammation and fibrosis, represents a milestone in the natural history of NAFLD and a critical time point in its progression. The purpose of this study was to analyze the diagnostic accuracy of the non-invasive Fibrotic NASH Index (FNI) in individuals with obesity undergoing bariatric surgery. Methods: This is a cross-sectional study, enrolling individuals who underwent bariatric surgery with liver biopsy at a tertiary university hospital. FNI was calculated, and a cutoff value was determined. Its diagnostic accuracy was then calculated through comparison with the gold standard test for this analysis (histopathological examination). Results: Of 128 participants, 83.6% were female, and the average age was 39.8 ± 8.7 years. The mean BMI was 38.7 ± 5.7 kg/m2. NAFLD was histologically confirmed in 76.6%, of which 81.6% had NASH. Histologically confirmed fibrotic NASH was observed in 22.7% of the general study population, 29.6% of individuals with NAFLD, and 36.3% of those with NASH. The mean FNI was 0.18 ± 0.19. An optimal cutoff point of 0.21 was determined, with an overall accuracy of 90.1%, an 82.8% sensitivity, a 90.8% specificity, a 72.6% positive predictive value, and a 94.7% negative predictive value. Conclusions: FNI provided adequate accuracy in detecting and ruling out fibrotic NASH. Considering the importance of fibrotic NASH within the natural history of NAFLD progression and the fact that this marker uses simple variables, it may be of great importance in high-risk populations, and its external validation and use should be encouraged. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Influence of losing weight in volumetric capnography and spirometry variables improvement: a case study/INFLUENCIA DA PERDA DE PESO NA MELHORA DAS VARIAVEIS ESPIROMETRICAS E NA CAPNOGRAFIA VOLUMETRICA: UM ESTUDO DE CASO

Author

Modena, Debora Aparecida Oliveira, Moreira, Marcos Mello, Paschoal, Ilma Aparecida, Pereira, Monica Corso, Martins, Luiz Claudio, Baltieri, Leticia, Gobato, Renata Cristina, Candido, Elaine Cristina, Neder, Ana Maria, Cazzo, Everton, and Chaim, Elinton Adami

Published
2019

33. Histological grading evaluation of non-alcoholic fatty liver disease after bariatric surgery: a retrospective and longitudinal observational cohort study

Author

Chaim, Felipe David Mendonça, Pascoal, Lívia Bitencourt, Chaim, Fábio Henrique Mendonça, Palma, Bruna Biazon, Damázio, Tiago Andrade, da Costa, Larissa Bastos Eloy, Carvalho, Rita, Cazzo, Everton, Gestic, Martinho Antônio, Utrini, Murillo Pimentel, Milanski, Marciane, Chaim, Elinton Adami, and Leal, Raquel Franco

Published
2020
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34. Impact of pre-operative weight loss on non-alcoholic fatty liver disease histopathology and insulin resistance in individuals undergoing bariatric surgery: a propensity matched cross-sectional comparison

Author

Maldonado, Fábio Henrique Ribeiro, Mega, Paulo Ferreira, Germano, Carlos Wustemberg, Dias, Luana Leite Castilho, Callejas, Guilherme Hoverter, Gestic, Martinho Antonio, Utrini, Murillo Pimentel, Chaim, Felipe David Mendonça, Callejas-Neto, Francisco, Chaim, Elinton Adami, and Cazzo, Everton

Subjects
Bariatric surgery, Weight loss, Hepatic lobular inflammation, Liver steatosis, Liver fibrosis, Insulin resistance, Obesity, Hepatic portal inflammation, Non-alcoholic steatohepatitis, Hepatocellular ballooning, Non-alcoholic fatty liver disease
Abstract

BACKGROUND: The effect of weight loss (WL) on histopathological aspects of non-alcoholic fatty liver disease (NAFLD) may provide further insights into the dynamics of hepatic recovery after WL. OBJECTIVE: To analyze the effects of pre-operative WL on insulin resistance- and NAFLD-related histology in individuals undergoing bariatric surgery (BS) with or without pre-operative WL. DESIGN AND SETTING: A matched cross-sectional study was conducted at a public university hospital and a private clinic in Campinas, Brazil. METHODS: An analytical, observational, cross-sectional study was conducted using prospectively collected databases of individuals who underwent BS and liver biopsy at either a public tertiary university hospital (with pre-operative WL) or a private clinic (without pre-operative WL). Random electronic matching by gender, age, and body mass index (BMI) was performed and two paired groups of 24 individuals each were selected. RESULTS: Of the 48 participants, 75% were female. The mean age was 37.4 ± 9.6. The mean BMI was 38.9 ± 2.6 kg/m2. Fibrosis was the most common histopathological abnormality (91.7%). Glucose was significantly lower in the WL group (92 ± 19.1 versus 111.8 ± 35.4 mg/dL; P = 0.02). Significantly lower frequencies of macrovesicular steatosis (58.3% versus 95.8%; P = 0.004), microvesicular steatosis (12.5% versus 87.5%; P < 0.001), and portal inflammation (50% versus 87.5%; P = 0.011) were observed in the WL group. CONCLUSION: Pre-operative WL was significantly associated with lower frequencies of macro- and mi- crovesicular steatosis, portal inflammation, and lower glycemia, indicating an association between the recent trajectory of body weight and histological aspects of NAFLD.

Published
2023

38. Trajectory of NAFLD characteristics after Roux-en-Y gastric bypass: a five-year historical cohort study

Author

Kreve, Fernanda, primary, Callejas, Guilherme Hoverter, additional, Jimenez, Laísa Simakawa, additional, Marques, Rodolfo Araújo, additional, Chaim, Felipe David Mendonça, additional, Utrini, Murillo Pimentel, additional, Gestic, Martinho Antonio, additional, Ramos, Almino Cardoso, additional, Chaim, Elinton Adami, additional, and Cazzo, Everton, additional

Published
2022
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43. Glucose Metabolism Parameters and Post-Prandial GLP-1 and GLP-2 Release Largely Vary in Several Distinct Situations: a Controlled Comparison Among Individuals with Crohn’s Disease and Individuals with Obesity Before and After Bariatric Surgery

Author

Magro, Daniéla Oliveira, Cazzo, Everton, Kotze, Paulo Gustavo, Vasques, Ana Carolina Junqueira, Martinez, Carlos Augusto Real, Chaim, Elinton Adami, Geloneze, Bruno, Pareja, José Carlos, and Coy, Cláudio Saddy Rodrigues

Published
2017
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50. Relationships of hepatic histopathological findings and bile microbiological aspects with bile duct injury repair surgical outcomes: A historical cohort

Author

Callejas, Guilherme Hoverter, primary, Marques, Rodolfo Araujo, additional, Gestic, Martinho Antonio, additional, Utrini, Murillo Pimentel, additional, Chaim, Felipe David Mendonça, additional, Chaim, Elinton Adami, additional, Callejas-Neto, Francisco, additional, and Cazzo, Everton, additional

Published
2022
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