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Background: According to traditional herbal medicine, chamomile has been considered as one of the herbal remedies for patients with polycystic ovary syndrome (PCOS). The study aimed to investigate the effect of chamomile on lipid and hormonal parameters in women of reproductive age with PCOS. Materials and Methods: This study is a randomized clinical trial which was conducted on 80 women (40 patients in each group) of childbearing age with PCO. The intervention group received 370 mg oral capsules of chamomile three times a day for 3 months. The control group did receive starch capsule (three times a day). Hormonal and lipid parameters were examined before and 3 months after the intervention. Results: The mean age of the patients was 22.40 ± 5.10 and 24.38 ± 6.14 years in the intervention and control groups, respectively. Decreased level of testosterone was observed in the intervention group (in women with PCOS) who received chamomile capsules (P = 0.017). A significant difference was not seen in low-density lipoprotein cholesterol level (P = 0.249), high-density lipoprotein cholesterol (P = 0.073), triglycerides (P = 0.603), the hormone dehydroepiandrosterone sulfate (P = 0.423), and the ratio of luteinizing hormone/follicle-stimulating hormone (LH/FSH) in the experimental and control groups after the intervention (P = 0.420). Conclusion: According to the findings, oral administration of chamomile capsule caused a significant decrease in total testosterone levels in these patients. However, no significant change was reported with lipid parameters, the ratio of LH/FSH, and dehydroepiandrosterone sulfate level. [ABSTRACT FROM AUTHOR]

Background: According to traditional herbal medicine, chamomile has been considered as one of the herbal remedies for patients with polycystic ovary syndrome (PCOS). The study aimed to investigate the effect of chamomile on lipid and hormonal parameters in women of reproductive age with PCOS. Materials and Methods: This study is a randomized clinical trial which was conducted on 80 women (40 patients in each group) of childbearing age with PCO. The intervention group received 370 mg oral capsules of chamomile three times a day for 3 months. The control group did receive starch capsule (three times a day). Hormonal and lipid parameters were examined before and 3 months after the intervention. Results: The mean age of the patients was 22.40 ± 5.10 and 24.38 ± 6.14 years in the intervention and control groups, respectively. Decreased level of testosterone was observed in the intervention group (in women with PCOS) who received chamomile capsules (P = 0.017). A significant difference was not seen in low-density lipoprotein cholesterol level (P = 0.249), high-density lipoprotein cholesterol (P = 0.073), triglycerides (P = 0.603), the hormone dehydroepiandrosterone sulfate (P = 0.423), and the ratio of luteinizing hormone/follicle-stimulating hormone (LH/FSH) in the experimental and control groups after the intervention (P = 0.420). Conclusion: According to the findings, oral administration of chamomile capsule caused a significant decrease in total testosterone levels in these patients. However, no significant change was reported with lipid parameters, the ratio of LH/FSH, and dehydroepiandrosterone sulfate level.

Pharmaceutical companies have a growing demand for herb raw material, including German chamomile ( Chamomilla recutita (L.) Rauschert), produced according to the rules of Good Agricultural Practices (GAP) for medicinal plants. These rules, among others, require limitation of the application of mineral fertilizers and pesticides. Catch crops can improve soil fertility and reduce weed infestation for subsequent crops. The aim of this study was to evaluate the effect of stubble catch crops and different nitrogen doses on anthodia and herb yield, and content and yield of essential oil from a diploid and tetraploid cultivar of German chamomile. In the 3-year experiment, two chamomile cultivars were grown – Mastar (2n) and Dukat (4n). They were sown after ploughing legume mixture or buckwheat ( Fagopyrum esculentum Moench) stubble catch crops; nitrogen fertilization rates were 0, 30, 60, and 90 kg N ha −1 . It was found that fertilization with 60 and 90 kg N ha −1 reduced chamomile weed infestation to a greater extent than the use of catch crops. The highest yield of anthodia was obtained after the application of the highest nitrogen rate. The herb and oil yield from herb were highest after the application of 60 kg N ha −1 . Cultivation of Dukat after a legume catch crop allowed for a reduction in nitrogen fertilizer rate from 90 to 60 kg N ha −1 without a decrease in anthodium yield. Buckwheat catch crop inhibited the growth of chamomile. A higher yield of anthodia was collected from the cultivar Dukat, but the essential oil content was higher in anthodia of Mastar. The content of chamazulen in essential oil from anthodia was 17.7 and 17.2%, α-bisabolol 23.0 and 21.1%, respectively, from Mastar and Dukat. The essential oil from herb contained mainly farnesene and en-in-dicycloether. The requirements of Good Agricultural Practices in chamomile cultivation can be met by the application of legume stubble catch crops, choice of suitable cultivar, and by adopting the nitrogen rate appropriate for the aim of cultivation. [ABSTRACT FROM AUTHOR]

The polymineral dust extracted from the camomile herb was exposed to gamma radiation. The glow curves from these polyminerals show a large, single thermoluminiscence (TL) peak, centred at about 440 K. Because the large structure of the glow curves, it seems that the TL signal could be produced by a trap distribution instead of a single level of traps. The kinetic parameters of the glow curves have been accurately analysed using the computerized glow curve deconvolution (CGCD) method applied at different steps during a fading experiment at room temperature (RT). Deconvolution has been performed using a continuous distribution of trapping levels, uniformly distributed, including one additional peak in the high temperature region. This peak has been modelled with second-order kinetics of trap motion. [ABSTRACT FROM AUTHOR]