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5. Venom Proteomics of Trimeresurus gracilis , a Taiwan-Endemic Pitviper, and Comparison of Its Venom Proteome and VEGF and CRISP Sequences with Those of the Most Related Species.

Author

Tse, Tsz-Chun, Tsai, Inn-Ho, Chan, Yuen-Ying, and Tsai, Tein-Shun

Subjects
VENOM, VASCULAR endothelial growth factors, LIQUID chromatography-mass spectrometry, AMINO acid oxidase, LECTINS, PROTEOMICS, VENOM glands, SERINE proteinases
Abstract

Trimeresurus gracilis is an endemic alpine pitviper in Taiwan with controversial phylogeny, and its venom proteome remains unknown. In this study, we conducted a proteomic analysis of T. gracilis venom using high-performance liquid chromatography-tandem mass spectrometry and identified 155 toxin proteoforms that belong to 13 viperid venom toxin families. By searching the sequences of trypsin-digested peptides of the separated HPLC fractions against the NCBI database, T. gracilis venom was found to contain 40.3% metalloproteases (SVMPs), 15.3% serine proteases, 6.6% phospholipases A2, 5.0% L-amino acid oxidase, 4.6% Cys-rich secretory proteins (CRISPs), 3.2% disintegrins, 2.9% vascular endothelial growth factors (VEGFs), 1.9% C-type lectin-like proteins, and 20.2% of minor toxins, nontoxins, and unidentified peptides or compounds. Sixteen of these proteoforms matched the toxins whose full amino-acid sequences have been deduced from T. gracilis venom gland cDNA sequences. The hemorrhagic venom of T. gracilis appears to be especially rich in PI-class SVMPs and lacks basic phospholipase A2. We also cloned and sequenced the cDNAs encoding two CRISP and three VEGF variants from T. gracilis venom glands. Sequence alignments and comparison revealed that the PI-SVMP, kallikrein-like proteases, CRISPs, and VEGF-F of T. gracilis and Ovophis okinavensis are structurally most similar, consistent with their close phylogenetic relationship. However, the expression levels of some of their toxins were rather different, possibly due to their distinct ecological and prey conditions. [ABSTRACT FROM AUTHOR]

Published
2023
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9. Cryptocurrency: An Analysis From An Institutional Investors Approach

Author

Chan, Yuen Ying and Chan, Yuen Ying

Abstract

In Anbetracht der Ereignisse, die weltweit und speziell auf den Finanzmärkten stattgefunden haben, sollten Anleger aktiv nach alternativen Anlagen suchen, um Risiken unabhängig von den Marktbedingungen abzusichern. Glücklicherweise sind Hedgefonds ein Instrument, das dafür bekannt ist, genau das zu tun. Dieses Papier zielt darauf ab, Hedge-Fonds- Anlagestrategien aus der Perspektive eines institutionellen Anlegers in Bezug auf Kryptowährungen zu diskutieren. Darüber hinaus bietet es einen Überblick und eine Analyse über 10 Kryptowährungen (Bitcoin, Bitcoin Cash, Dash, EOS, Ethereum, Ethereum Classic, Litecoin, Monero, XRP und ZCash), da es als Leitfaden für Investoren dienen soll, um zu entscheiden, ob es eine gute Idee sein kann, in Kryptowährungen zu investieren, indem man Hedgefonds-Strategien nachahmt. Die Ergebnisse zeigen, dass durch die Nachahmung von Hedge-Fonds-Strategien eine Überschussrendite im Portfolio eines Anlegers erzielt werden kann, allerdings müssen die Anleger ein höheres Risiko tragen.*****Considering the events that have occurred throughout the world and specifically within financial markets, investors should actively seek alternative investments to hedge risks regardless of market conditions. Fortunately, hedge funds are a tool known for performing exactly that. This paper aims to discuss hedge fund investment strategies in the approach of an institutional investors perspective on cryptocurrency. Furthermore, it provides an overview and analysis on 10 cryptocurrencies (Bitcoin, Bitcoin Cash, Dash, EOS, Ethereum, Ethereum Classic, Litecoin, Monero, XRP and ZCash) as it aims to act as a guide for investors to help decide whether it may be a good idea to invest in cryptocurrency by replicating hedge fund strategies. The results show that by imitating hedge fund strategies, it could create excess return in an investors portfolio, however investors have to bear more risk.

Published
2021

10. Why Hong Kong Is Still Marching

Author

Chan, Yuen Ying

Subjects
General interest
Abstract

Byline: Yuen Ying Chan 'I believe that we cannot withdraw this bill, or else society will say that this bill was groundless,' Carrie Lam, Hong Kong's chief executive, said at [...]

Published
2019

12. Enabling the disabled: media use and communication needs of people with disabilities during and after the Sichuan earthquake in China

Author

Fu, King-wa, White, James, Chan, Yuen-ying, Zhou, Ling, Zhang, Qiang, and Lu, Qibin

Subjects
Earthquakes -- China, Earthquakes -- Environmental aspects, Disabled persons -- Equipment and supplies, Wireless telecommunications equipment -- Usage, Emergency management, Wireless telecommunications equipment, Government, Social sciences
Abstract

Byline: King-wa Fu, James White, Yuen-ying Chan, Ling Zhou, Qiang Zhang, Qibin Lu The importance of effective communications in extreme emergency situations, such as earthquakes, is widely recognised (Lee, 2008), whether the communications relate to disaster preparedness, response or recovery. More problematic is the connection between disaster communications and the situation of people with disabilities in emergency situations. In times of crisis, do the communication needs of people with disabilities differ from those of the wider population? This study aims to understand the use of media and risk communication situation before, during and after the 2008 earthquake in Sichuan province in China, with a special focus on the experiences of people with disabilities. The analysis includes recommendations for best practices.

Published
2010

13. The English-language media in Hong Kong

Author

Chan Yuen-Ying

Subjects
Linguistics and Language, Media conglomerate, Sociology and Political Science, Media studies, Colonialism, Language and Linguistics, New media, Newspaper, Audience measurement, Globalization, Anthropology, Political science, China, News media
Abstract

The forces of de-colonization and globalization have shaped the development of the English-language news media in Hong Kong over the past two decades. When in the mid-1980s Hong Kong began the transition to Chinese sovereignty, the position of influence of the local English-language press began to erode while the Chinese-language newspapers started to proliferate and expand their readership. As Hong Kong moved out of the colonial era, however, a countertrend emerged with international English-language media conglomerates, mostly US-owned, extending their reach and reshaping Hong Kong's identity. The images of Hong Kong projected by the colonial press and then by the international media have often been distorted, reflecting the cultural biases of their writers, editors and producers. To increase Hong Kong's representation in an era of ‘new media,’ Hong Kong needs a new type of bilingual media professional with a high level of English proficiency who can contest the assumptions and biases in the English-language news coverage of Hong Kong and China.

Published
2000

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