127 results on '"Chandrasekhar, Srinivasan"'
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2. In vitro Regulation of Cartilage Matrix Assembly by a Mr 54,000 Collagen-Binding Protein
3. Interaction of Fibronectin with Collagen: Age-Specific Defect in the Biological Activity of Human Fibroblast Fibronectin
4. Regulation of NFATc2 gene expression by the transcription factor Runx2
5. Differential regulation of cytokine-induced MMP-1 and MMP-13 expression by p38 kinase inhibitors in human chondrosarcoma cells: potential role of Runx2 in mediating p38 effects
6. Regulation of the human ADAMTS-4 promoter by transcription factors and cytokines
7. Identification and characterization of noncalcemic, tissue-selective, nonsecosteroidal vitamin D receptor modulators
8. lambda-DB: An ODMG-Based Object-Oriented DBMS.
9. Catabolic Effects of Continuous Human PTH (1-38) in Vivo Is Associated with Sustained Stimulation of RANKL and Inhibition of Osteoprotegerin and Gene-Associated Bone Formation
10. Distinct pathways of extracellular signal-regulated kinase activation by growth factors, fibronectin and parathyroid hormone 1–34
11. Degradative and Repair Responses of Cartilage to Cytokines and Growth Factors Occur Via Distinct Pathways
12. Protein Kinase C Is a Mediator of the Synthesis and Secretion of Osteoprotegerin in Osteoblast-like Cells
13. Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1
14. Crystal Structure of Human Parathyroid Hormone 1–34 at 0.9-Å Resolution
15. Activation of Osteocalcin Transcription Involves Interaction of Protein Kinase A- and Protein Kinase C-dependent Pathways
16. Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors
17. Identification and biological activity of 6-alkyl-substituted 3-methyl-pyridine-2-carbonyl amino dimethyl-benzoic acid EP4 antagonists
18. Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2,4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profile
19. Discovery of substituted-2,4-dimethyl-(naphthalene-4-carbonyl)amino-benzoic acid as potent and selective EP4 antagonists
20. Parathyroid Hormone-(1–34) Enhances Aggrecan Synthesis via an Insulin-like Growth Factor-I Pathway
21. Discovery and characterization of a potent and selective EP4 receptor antagonist
22. Analgesic and anti-inflammatory properties of novel, selective, and potent EP4 receptor antagonists
23. Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design
24. Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors
25. Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics
26. λ-DB
27. A Nonsecosteroidal Vitamin D Receptor Modulator Ameliorates Experimental Autoimmune Encephalomyelitis without Causing Hypercalcemia
28. Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors.
29. Regulation of NFATc2 gene expression by the transcription factor Runx2
30. Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1–38 inhibition of osteoprotegerin gene expression
31. Parathyroid hormone (1–34) regulates integrin expression in vivo in rat osteoblasts
32. Identification and Characterization of Novel Microsomal Prostaglandin E Synthase-1 Inhibitors for Analgesia
33. Development of a Scintillation Proximity Assay for High-Throughput Measurement of Intact Parathyroid Hormone
34. Parathyroid Hormone (PTH 1–34) Regulation of Rat Osteocalcin Gene Transcription
35. Modulation of PDGF mediated osteoblast chemotaxis by leukemia inhibitory factor LIF
36. The anti-rheumatic potential of a series of 2,4-di-substituted-4H-naphtho[1,2-b]pyran-3-carbonitriles
37. Osteonectin/SPARC is a product of articular chondrocytes/cartilage and is regulated by cytokines and growth factors
38. Intra-Articular Administration of Interleukin-1 Causes Prolonged Suppression of Cartilage Proteoglycan Synthesis in Rats
39. Differential regulation of metalloprotease steady‐state mRNA levels by IL‐1 and FGF in rabbit articular chondrocytes
40. A Nonsecosteroidal Vitamin D Receptor Modulator Ameliorates Experimental Autoimmune Encephalomyelitis without Causing Hypercalcemia.
41. Interleukin-1 -induced suppression of type II collagen gene transcription involves DNA regulatory elements
42. Arthritis induced by interleukin-1 is dependent on the site and frequency of intraarticular injection
43. Passive Role of Articular Chondrocytes in Quinolone-Induced Arthropathy in Guinea Pigs
44. Fibronectin from aged fibroblasts is defective in promoting cellular adhesion.
45. Transforming growth factor-beta and fibroblast growth factor act synergistically to inhibit collagen II synthesis through a mechanism involving regulatory DNA sequences.
46. Induction of interleukin-1 receptors on chondrocytes by fibroblast growth factor: A possible mechanism for modulation of interleukin-1 activity.
47. Microdetermination of proteoglycans and glycosaminoglycans in the presence of guanidine hydrochloride
48. Interleukin-1-induced alterations in proteoglycan metabolism and matrix assembly
49. Regulation of Type I Collagen Fibril Assembly by Link Protein and Proteoglycans
50. Transforming growth factor-β is a potent inhibitor of IL-1 induced protease activity and cartilage proteoglycan degradation
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