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11. Viruses

Author

Chang, Chung-Ming, Wallenhorst, Nathanaël, editor, and Wulf, Christoph, editor

Published
2023
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12. New Viruses

Author

Chang, Chung-Ming, Mukherjee, Riya, Pandey, Ramendra Pati, Wallenhorst, Nathanaël, editor, and Wulf, Christoph, editor

Published
2023
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32. A systematic assessment of Leishmania donovani infection in domestic and wild animal reservoir hosts of zoonotic Visceral Leishmaniasis

Author

Pandey, Ramendra Pati, primary, Peer, Gajala Deethamvali Ghouse, additional, Priyadarshini, Anjali, additional, Gupta, Archana, additional, Vibhuti, Arpana, additional, Leal, Elcio, additional, Costa, Antonio Charlys da, additional, Prudencio, Carlos, additional, Chang, Chung-Ming, additional, and Raj, V. Samuel, additional

Published
2023
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34. Scrub typhus in Northeast India: epidemiology, clinical presentations, and diagnostic approaches.

Author

Konyak, Beyau M, Soni, Monika, Saikia, Shyamalima, Chang, Tochi, Gogoi, Indrani, Khongstid, Ibakmensi, Chang, Chung-Ming, Sharma, Mohan, and Pandey, Ramendra Pati

Subjects
TSUTSUGAMUSHI disease, SYMPTOMS, RODENT populations, NEGLECTED diseases, EPIDEMIOLOGY, CORONAVIRUSES
Abstract

Scrub typhus is one of the most neglected tropical diseases, a leading cause of acute undifferentiated febrile illness in areas of the 'tsutsugamushi triangle', diagnosed frequently in South Asian countries. The bacteria Orientia tsutsugamushi is the causative agent of the disease, which enters the human body through the bite of trombiculid mites (also known as chiggers) of the genus Leptotrombidium deliense. Diagnosis of the disease is challenging, as its early symptoms mimic other febrile illnesses like dengue, influenza and corona viruses. Lack of rapid, reliable and cost-effective diagnostic methods further complicates the identification process. Northeast India, a mountainous region with a predominantly rural tribal population, has witnessed a resurgence of scrub typhus cases in recent years. Various ecological factors, including rodent populations, habitat characteristics and climatic conditions, influence its prevalence. Entomological investigations have confirmed the abundance of vector mites, highlighting the importance of understanding their distribution and the probability of transmission of scrub typhus in the region. Proper diagnosis, awareness campaigns and behavioural interventions are essential for controlling scrub typhus outbreaks and reducing its impact on public health in Northeast India. Further research and community-based studies are necessary to accurately assess the disease burden and implement effective prevention strategies. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Exploring Disease Management and Control through Pathogen Diagnostics and One Health Initiative: A Concise Review.

Author

Mukherjee, Riya, Vidic, Jasmina, Auger, Sandrine, Wen, Hsiao-Chuan, Pandey, Ramendra Pati, and Chang, Chung-Ming

Subjects
DISEASE management, PREVENTIVE medicine, RAPID diagnostic tests, ENVIRONMENTAL health, ANIMAL health, FOOT & mouth disease, EMERGING infectious diseases
Abstract

The "One Health" initiative is a critical strategy that recognizes the interconnectedness between human, animal, and environmental health in the spread and containment of infectious pathogens. With the ease of global transportation, transboundary disease outbreaks pose a significant threat to food safety and security, endangering public health and having a negative economic impact. Traditional diagnostic techniques based on genotypic and phenotypic analyses are expensive, time-consuming, and cannot be translated into point-of-care tools, hindering effective disease management and control. However, with advancements in molecular methods, biosensors, and new generation sequencing, rapid and reliable diagnostics are now available. This review provides a comprehensive insight into emergent viral and bacterial pathogens and antimicrobial resistance, highlighting the importance of "One Health" in connecting detection and effective treatment. By emphasizing the symbiotic relationship between human and animal health, this paper underscores the critical role of "One Health" initiatives in preventing and controlling infectious diseases. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Chitosan: Applications in Drug Delivery System

Author

Pandey, Ramendra Pati, primary, Kumar, Suresh, additional, Dhiman, Ruby, additional, Prudencio, Carlos R., additional, da Costa, Antonio Charlys, additional, Vibhuti, Arpana, additional, Leal, Elcio, additional, Chang, Chung-Ming, additional, and Raj, Vethakkani Samuel, additional

Published
2023
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47. Exploration of Antileishmanial Compounds Derived from Natural Sources

Author

Peer, Gajala Deethamvali Ghouse, Chang, Chung-Ming, Samuel Raj, V., and Pandey, Ramendra

Subjects
microbiology
Abstract

Leishmaniasis is considered one of the different neglected tropical diseases by the World Health Organization. Over the past few decades to tackle leishmaniasis, effective and novel drugs have progressed. But few are expensive some other medication shows poor effects and few drugs with long treatment lead to cause resistance. But it is very important to start a better medication against leishmania so researchers came to the front of the utilization of natural products which are considered a better option. Finding active compounds in medicinal plants is another alternative to currently accessible medications. Materials and methods: This study examined and reported the far more potential natural products used to treat disease caused by Leishmania spp. Leishmaniasis, plant metabolites, in vivo, in vitro, and treatment against leishmaniasis have been used as search terms in the Google Scholar, PubMed, and Science Direct databases, and only papers published between 2015 and 2021 have been chosen for further analysis. Results: The use of novel natural compounds with leishmanicidal action as well as the leishmanicidal activity of natural compounds against promastigote, axenic, and intracellular amastigote forms were included in roughly 20 research papers that were reviewed.Conclusion: Due to their capacity to selectively target parasites without harming host cell viability, herbal plants are a possible source of new anti-leishmanial medication. Future leishmaniasis treatments will draw on the isolated compounds as a source, completing those already offered in clinics.

Published
2022

49. Aedes aegypti Totivirus identified in mosquitoes in the Brazilian Amazon region

Author

Leal, Élcio, primary, Ribeiro, Edcelha Soares D.’Athaide, additional, Monteiro, Fred Julio Costa, additional, Marques, Julia Pantoja, additional, dos Santos Mendes, Diuliana, additional, Morais, Vanessa S., additional, Araújo, Emerson Luiz Lima, additional, Pandey, Ramendra Pati, additional, Chang, Chung-Ming, additional, Deng, Xutao, additional, Delwart, Eric, additional, da Costa, Antonio Charlys, additional, and Lima, Kledoaldo, additional

Published
2022
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