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Wu H, Liu Y, Chen L, et al. Int J Nanomedicine. 2022;17:6377–6398. The authors have advised there is an error in Figure 8A on page 6392. Due to an error that occurred inadvertently at the time of figure assembly, the images of the fluorescence intensity of RVG15-PEG@IR-820@ZIF-8 at the 8 h are incorrect. The correct Figure 8 is as follows Figure 8 Continued. Figure 8 Biodistribution of free IR-820, IR-820@ZIF-8, and RVG15-PEG@IR-820@ZIF-8 in vivo. (A) In vivo fluorescence imaging of orthotopic glioma-bearing mice treated with free IR-820, IR-820@ZIF-8, and RVG15-PEG@IR-820@ZIF-8 at 1, 4, 8, and 24 h. (B) Ex vivo fluorescence images of the excised brains and major organs at 24 h after injection. (C) Quantitative region-of-interest analysis of (B). Means ± SD, n = 3; *P < 0.05. . The authors wish to apologize for this error and advise it does not affect the interpretation of the data and the conclusion of the study.

Hao Wu,1,2 Yanhong Liu,2 Liqing Chen,2 Shuangqing Wang,1,2 Chao Liu,2 Heming Zhao,2 Mingji Jin,1,2 Shuangyan Chang,2 Xiuquan Quan,3 Minhu Cui,3 Hongshuang Wan,2,3 Zhonggao Gao,1,2 Wei Huang2 1Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, People’s Republic of China; 2State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, People’s Republic of China; 3Department of Gastroenterology, Yanbian University Hospital, Yanji, Jilin Province, 133000, People’s Republic of ChinaCorrespondence: Zhonggao Gao; Wei Huang, Tel +86 10 63028096 ; +86 10 63026505, Email zggao@imm.ac.cn; huangwei@imm.ac.cnIntroduction: The blood–brain barrier (BBB) is a key obstacle to the delivery of drugs into the brain. Therefore, it is essential to develop an advanced drug delivery nanoplatform to solve this problem. We previously screened a small rabies virus glycoprotein 15 (RVG15) peptide with 15 amino acids and observed that most of the RVG15-modified nanoparticles entered the brain within 1 h of administration. The high BBB penetrability gives RVG15 great potential for brain-targeted drug delivery systems. Moreover, a multifunctional integrated nanoplatform with a high drug-loading capacity, tunable functionality, and controlled drug release is crucial for tumor treatment. Zeolitic imidazolate framework (ZIF-8) is a promising nanodrug delivery system.Methods: Inspired by the biomimetic concept, we designed RVG15-coated biomimetic ZIF-8 nanoparticles (RVG15-PEG@DTX@ZIF-8) for docetaxel (DTX) delivery to achieve efficient glioblastoma elimination in mice. This bionic nanotherapeutic system was prepared by one-pot encapsulation, followed by coating with RVG15-PEG conjugates. The size, morphology, stability, drug-load