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Automatic diagnosis of malignant prostate cancer patients from mpMRI has been studied heavily in the past years. Model interpretation and domain drift have been the main road blocks for clinical utilization. As an extension from our previous work where we trained a customized convolutional neural network on a public cohort with 201 patients and the cropped 2D patches around the region of interest were used as the input, the cropped 2.5D slices of the prostate glands were used as the input, and the optimal model were searched in the model space using autoKeras. Something different was peripheral zone (PZ) and central gland (CG) were trained and tested separately, the PZ detector and CG detector were demonstrated effectively in highlighting the most suspicious slices out of a sequence, hopefully to greatly ease the workload for the physicians., Comment: arXiv admin note: text overlap with arXiv:1903.12331

EBEX was a long-duration balloon-borne experiment to measure the polarization of the cosmic microwave background. The experiment had three frequency bands centered at 150, 250, and 410 GHz and was the first to use a kilo-pixel array of transition edge sensor (TES) bolometers aboard a balloon platform; shortly after reaching float we operated 504, 342, and 109 TESs at each of the bands, respectively. We describe the design and characterization of the array and the readout system. We give the distributions of measured thermal conductances, normal resistances, and transition temperatures. With the exception of the thermal conductance at 150 GHz. We measured median low-loop-gain time constants $\tau_{0}=$ 88, 46, and 57 ms and compare them to predictions. Two measurements of bolometer absorption efficiency show high ($\sim$0.9) efficiency at 150 GHz and medium ($\sim$0.35, and $\sim$0.25) at the two higher bands, respectively. We measure a median total optical load of 3.6, 5.3 and 5.0 pW absorbed at the three bands, respectively. EBEX pioneered the use of the digital version of the frequency domain multiplexing (FDM) system which multiplexed the bias and readout of 16 bolometers onto two wires. We present accounting of the measured noise equivalent power. The median per-detector noise equivalent temperatures referred to a black body with a temperature of 2.725 K are 400, 920, and 14500 $\mu$K$\sqrt{s}$ for the three bands, respectively. We compare these values to our pre-flight predictions and to a previous balloon payload, discuss the sources of excess noise, and the path for a future payload to make full use of the balloon environment., Comment: Accepted by The Astrophysical Journal Supplement Series (APJS). 49 pages, 28 figures, 11 tables

We discuss a systematic effect associated with measuring polarization with a continuously rotating half-wave plate. The effect was identified with the data from the E and B Experiment (EBEX), which was a balloon-borne instrument designed to measure the polarization of the CMB as well as that from Galactic dust. The data show polarization fraction larger than 10\% while less than 3\% were expected from instrumental polarization. We give evidence that the excess polarization is due to detector non-linearity in the presence of a continuously rotating HWP. The non-linearity couples intensity signals into polarization. We develop a map-based method to remove the excess polarization. Applying this method for the 150 (250) GHz bands data we find that 81\% (92\%) of the excess polarization was removed. Characterization and mitigation of this effect is important for future experiments aiming to measure the CMB B-modes with a continuously rotating HWP., Comment: 43 pages, 12 figures, submitted to the Astrophysical Journal

The E and B Experiment (EBEX) was a long-duration balloon-borne cosmic microwave background polarimeter that flew over Antarctica in 2013. We describe the experiment's optical system, receiver, and polarimetric approach, and report on their in-flight performance. EBEX had three frequency bands centered on 150, 250, and 410 GHz. To make efficient use of limited mass and space we designed a 115 cm$^{2}$sr high throughput optical system that had two ambient temperature mirrors and four anti-reflection coated polyethylene lenses per focal plane. All frequency bands shared the same optical train. Polarimetry was achieved with a continuously rotating achromatic half-wave plate (AHWP) that was levitated with a superconducting magnetic bearing (SMB). Rotation stability was 0.45 % over a period of 10 hours, and angular position accuracy was 0.01 degrees. This is the first use of a SMB in astrophysics. The measured modulation efficiency was above 90 % for all bands. To our knowledge the 109 % fractional bandwidth of the AHWP was the broadest implemented to date. The receiver that contained one lens and the AHWP at a temperature of 4 K, the polarizing grid and other lenses at 1 K, and the two focal planes at 0.25 K performed according to specifications giving focal plane temperature stability with fluctuation power spectrum that had $1/f$ knee at 2 mHz. EBEX was the first balloon-borne instrument to implement technologies characteristic of modern CMB polarimeters including high throughput optical systems, and large arrays of transition edge sensor bolometric detectors with mutiplexed readouts., Comment: 49 pages, 32 figures, submitted to The Astrophysical Journal Supplement

The E and B Experiment (EBEX) was a long-duration balloon-borne instrument designed to measure the polarization of the cosmic microwave background (CMB) radiation. EBEX was the first balloon-borne instrument to implement a kilo-pixel array of transition edge sensor (TES) bolometric detectors and the first CMB experiment to use the digital version of the frequency domain multiplexing system for readout of the TES array. The scan strategy relied on 40 s peak-to-peak constant velocity azimuthal scans. We discuss the unique demands on the design and operation of the payload that resulted from these new technologies and the scan strategy. We describe the solutions implemented including the development of a power system designed to provide a total of at least 2.3 kW, a cooling system to dissipate 590 W consumed by the detectors' readout system, software to manage and handle the data of the kilo-pixel array, and specialized attitude reconstruction software. We present flight performance data showing faultless management of the TES array, adequate powering and cooling of the readout electronics, and constraint of attitude reconstruction errors such that the spurious B-modes they induced were less than 10% of CMB B-mode power spectrum with $r=0.05$., Comment: 37 pages, 16 figures, accepted for publication in ApJ Supp

The E and B experiment (EBEX) is a balloon-borne telescope designed to measure the polarization of the cosmic microwave background with 8' resolution employing a gondola scanning with speeds of order degree per second. In January 2013, EBEX completed 11 days of observations in a flight over Antarctica covering $\sim$ 6000 square degrees of the sky. The payload is equipped with two redundant star cameras and two sets of three orthogonal gyroscopes to reconstruct the telescope attitude. The EBEX science goals require the pointing to be reconstructed to approximately 10" in the map domain, and in-flight attitude control requires the real time pointing to be accurate to $\sim$ 0.5$^{\circ}$ . The high velocity scan strategy of EBEX coupled to its float altitude only permits the star cameras to take images at scan turnarounds, every $\sim$ 40 seconds, and thus requires the development of a pointing system with low noise gyroscopes and carefully controlled systematic errors. Here we report on the design of the pointing system and on a simulation pipeline developed to understand and minimize the effects of systematic errors. The performance of the system is evaluated using the 2012/2013 flight data, and we show that we achieve a pointing error with RMS=25" on 40 seconds azimuth throws, corresponding to an error of $\sim$ 4.6" in the map domain., Comment: 14 pages, Proceedings of the 2015 IEEE Aerospace Conference

The E and B Experiment (EBEX) is a balloon-borne polarimeter designed to measure the polarization of the cosmic microwave background radiation and to characterize the polarization of galactic dust. EBEX was launched December 29, 2012 and circumnavigated Antarctica observing $\sim$6,000 square degrees of sky during 11 days at three frequency bands centered around 150, 250 and 410 GHz. EBEX was the first experiment to operate a kilo-pixel array of transition-edge sensor bolometers and a continuously rotating achromatic half-wave plate aboard a balloon platform. It also pioneered the use of detector readout based on digital frequency domain multiplexing. We describe the temperature calibration of the experiment. The gain response of the experiment is calibrated using a two-step iterative process. We use signals measured on passes across the Galactic plane to convert from readout-system counts to power. The effective smoothing scale of the EBEX optics and the star camera-to-detector offset angles are determined through \c{hi}2 minimization using the compact HII region RCW 38. This two-step process is initially performed with parameters measured before the EBEX 2013 flight and then repeated until the calibration factor and parameters converge., Comment: 6 pages, 3 figures, Proceedings of the 14th Marcel Grossman Conference

The E and B Experiment (EBEX) is a balloon-borne telescope designed to probe polarization signals in the CMB resulting from primordial gravitational waves, gravitational lensing, and Galactic dust emission. EBEX completed an 11 day flight over Antarctica in January 2013 and data analysis is underway. EBEX employs two star cameras to achieve its real-time and post-flight pointing requirements. We wrote a software application called STARS to operate, command, and collect data from each of the star cameras, and to interface them with the main flight computer. We paid special attention to make the software robust against potential in-flight failures. We report on the implementation, testing, and successful in flight performance of STARS., Comment: 14 pages, 6 figures, SPIE conference proceedings

EBEX is a balloon-borne telescope designed to measure the polarization of the cosmic microwave background radiation. During its eleven day science flight in the Austral Summer of 2012, it operated 955 spider-web transition edge sensor (TES) bolometers separated into bands at 150, 250 and 410 GHz. This is the first time that an array of TES bolometers has been used on a balloon platform to conduct science observations. Polarization sensitivity was provided by a wire grid and continuously rotating half-wave plate. The balloon implementation of the bolometer array and readout electronics presented unique development requirements. Here we present an outline of the readout system, the remote tuning of the bolometers and Superconducting QUantum Interference Device (SQUID) amplifiers, and preliminary current noise of the bolometer array and readout system., Comment: 15 pages, 12 figures, SPIE conference proceedings

EBEX is a NASA-funded balloon-borne experiment designed to measure the polarization of the cosmic microwave background (CMB). Observations will be made using 1432 transition edge sensor (TES) bolometric detectors read out with frequency multiplexed SQuIDs. EBEX will observe in three frequency bands centered at 150, 250, and 410 GHz, with 768, 384, and 280 detectors in each band, respectively. This broad frequency coverage is designed to provide valuable information about polarized foreground signals from dust. The polarized sky signals will be modulated with an achromatic half wave plate (AHWP) rotating on a superconducting magnetic bearing (SMB) and analyzed with a fixed wire grid polarizer. EBEX will observe a patch covering ~1% of the sky with 8' resolution, allowing for observation of the angular power spectrum from \ell = 20 to 1000. This will allow EBEX to search for both the primordial B-mode signal predicted by inflation and the anticipated lensing B-mode signal. Calculations to predict EBEX constraints on r using expected noise levels show that, for a likelihood centered around zero and with negligible foregrounds, 99% of the area falls below r = 0.035. This value increases by a factor of 1.6 after a process of foreground subtraction. This estimate does not include systematic uncertainties. An engineering flight was launched in June, 2009, from Ft. Sumner, NM, and the long duration science flight in Antarctica is planned for 2011. These proceedings describe the EBEX instrument and the North American engineering flight., Comment: 12 pages, 9 figures, Conference proceedings for SPIE Millimeter, Submillimeter, and Far-Infrared Detectors and Instrumentation for Astronomy V (2010)

We present the hardware and software systems implementing autonomous operation, distributed real-time monitoring, and control for the EBEX instrument. EBEX is a NASA-funded balloon-borne microwave polarimeter designed for a 14 day Antarctic flight that circumnavigates the pole. To meet its science goals the EBEX instrument autonomously executes several tasks in parallel: it collects attitude data and maintains pointing control in order to adhere to an observing schedule; tunes and operates up to 1920 TES bolometers and 120 SQUID amplifiers controlled by as many as 30 embedded computers; coordinates and dispatches jobs across an onboard computer network to manage this detector readout system; logs over 3~GiB/hour of science and housekeeping data to an onboard disk storage array; responds to a variety of commands and exogenous events; and downlinks multiple heterogeneous data streams representing a selected subset of the total logged data. Most of the systems implementing these functions have been tested during a recent engineering flight of the payload, and have proven to meet the target requirements. The EBEX ground segment couples uplink and downlink hardware to a client-server software stack, enabling real-time monitoring and command responsibility to be distributed across the public internet or other standard computer networks. Using the emerging dirfile standard as a uniform intermediate data format, a variety of front end programs provide access to different components and views of the downlinked data products. This distributed architecture was demonstrated operating across multiple widely dispersed sites prior to and during the EBEX engineering flight., Comment: 11 pages, to appear in Proceedings of SPIE Astronomical Telescopes and Instrumentation 2010; adjusted metadata for arXiv submission

We describe the cryostat and supporting electronics for the EBEX experiment. EBEX is a balloon-borne polarimeter designed to measure the B-mode polarization of the cosmic microwave background radiation. The instrument includes a 1.5 meter Gregorian-type telescope and 1432 bolometric transition edge sensor detectors operating at 0.3 K. Electronics for monitoring temperatures and controlling cryostat refrigerators is read out over CANbus. A timing system ensures the data from all subsystems is accurately synchronized. EBEX completed an engineering test flight in June 2009 during which the cryogenics and supporting electronics performed according to predictions. The temperatures of the cryostat were stable, and an analysis of a subset of the data finds no scan synchronous signal in the cryostat temperatures. Preparations are underway for an Antarctic flight., Comment: 11 pages, 6 figures, Proceedings of the 12th Marcel Grossman Conference