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4. Pediatric AKI in the real world: changing outcomes through education and advocacy—a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference

Author

Mottes, Theresa, Menon, Shina, Conroy, Andrea, Jetton, Jennifer, Dolan, Kristin, Arikan, Ayse Akcan, Basu, Rajit K., Goldstein, Stuart L., Symons, Jordan M., Alobaidi, Rashid, Askenazi, David J., Bagshaw, Sean M., Barhight, Matthew, Barreto, Erin, Bayrakci, Benan, Ray, II, O. N. Bignall, Bjornstad, Erica, Brophy, Patrick, Charlton, Jennifer, Chanchlani, Rahul, Conroy, Andrea L., Deep, Akash, Devarajan, Prasad, Fuhrman, Dana, Gist, Katja M., Gorga, Stephen M., Greenberg, Jason H., Hasson, Denise, Heydari, Emma, Iyengar, Arpana, Krawczeski, Catherine, Meigs, Leslie, Morgan, Catherine, Morgan, Jolyn, Neumayr, Tara, Ricci, Zaccaria, Selewski, David T., Soranno, Danielle, Stanski, Natalja, Starr, Michelle, Sutherland, Scott M., Symons, Jordan, Tavares, Marcelo, Vega, Molly, Zappitelli, Michael, Ronco, Claudio, Mehta, Ravindra L., Kellum, John, and Ostermann, Marlies

Published
2024
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17. Resting-state MRI reveals spontaneous physiological fluctuations in the kidney and tracks diabetic nephropathy in rats.

Author

Baldelomar, Edwin J., Morozov, Darya, Wilson, Leslie D., Eldeniz, Cihat, Hongyu An, Charlton, Jennifer R., Bauer, Adam Q., Keilholz, Shella D., Hulbert, Monica L., and Bennett, Kevin M.

Subjects
DIABETIC nephropathies, KIDNEY cortex, LABORATORY rats, KIDNEYS, MAGNETIC resonance imaging
Abstract

The kidneys maintain fluid-electrolyte balance and excrete waste in the presence of constant fluctuations in plasma volume and systemic blood pressure. The kidneys perform these functions to control capillary perfusion and glomerular filtration by modulating the mechanisms of autoregulation. An effect of these modulations are spontaneous, natural fluctuations in glomerular perfusion. Numerous other mechanisms can lead to fluctuations in perfusion and flow. The ability to monitor these spontaneous physiological fluctuations in vivo could facilitate the early detection of kidney disease. The goal of this work was to investigate the use of resting-state magnetic resonance imaging (rsMRI) to detect spontaneous physiological fluctuations in the kidney. We performed rsMRI of rat kidneys in vivo over 10 min, applying motion correction to resolve time series in each voxel. We observed spatially variable, spontaneous fluctuations in rsMRI signal between 0 and 0.3 Hz, in frequency bands associated with autoregulatory mechanisms. We further applied rsMRI to investigate changes in these fluctuations in a rat model of diabetic nephropathy. Spectral analysis was performed on time series of rsMRI signals in the kidney cortex and medulla. The power from spectra in specific frequency bands from the cortex correlated with severity of glomerular pathology caused by diabetic nephropathy. Finally, we investigated the feasibility of using rsMRI of the human kidney in two participants, observing the presence of similar, spatially variable fluctuations. This approach may enable a range of preclinical and clinical investigations of kidney function and facilitate the development of new therapies to improve outcomes in patients with kidney disease. NEW & NOTEWORTHY This work demonstrates the development and use of resting-state MRI to detect low-frequency, spontaneous physiological fluctuations in the kidney consistent with previously observed fluctuations in perfusion and potentially due to autoregulatory function. These fluctuations are detectable in rat and human kidneys, and the power of these fluctuations is affected by diabetic nephropathy in rats. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Maternal Hypertension Disorders and Neonatal Acute Kidney Injury: Results from the AWAKEN Study.

Author

DeFreitas, Marissa J., Griffin, Russell, Sanderson, Keia, Nada, Arwa, Charlton, Jennifer R., Jetton, Jennifer G., Kent, Alison L., Guillet, Ronnie, Askenazi, David, Abitbol, Carolyn L., Ambalavanan, Namasivayam, Goldstein, Stuart, Nathan, Amy, Greenberg, James, KentAlisonMD, Kent, Alison, Fletcher, Jeffrey, Sethna, Farah, Soranno, Danielle, and Gien, Jason

Subjects
RISK assessment, RESEARCH funding, NEONATAL intensive care units, LOGISTIC regression analysis, ACUTE kidney failure, NEONATAL intensive care, RETROSPECTIVE studies, CHI-squared test, HYPERTENSION in pregnancy, LONGITUDINAL method, ODDS ratio, MEDICAL records, ACQUISITION of data, PREECLAMPSIA, ANALYSIS of variance, PREGNANCY complications, ECLAMPSIA, DISEASE risk factors, DISEASE complications, CHILDREN
Abstract

Objective This study aimed to examine the association between maternal hypertension (HTN) exposure and neonatal acute kidney injury (AKI). Study Design Retrospective cohort study of 2,162 neonates admitted to 24 neonatal intensive care units (NICUs). Neonates were classified into the following exposure groups: any maternal HTN, chronic maternal HTN, preeclampsia/eclampsia, both, or neither. Demographics, clinical characteristics, and AKI status were compared using Chi-square and analysis of variance. General estimating logistic regression was used to estimate adjusted odds ratios and included a stratified analysis for site of delivery. Result Neonates exposed to any maternal HTN disorder had a tendency toward less overall and early AKI. When stratified by inborn versus outborn, exposure to both maternal HTN disorders was associated with a significantly reduced odds of early AKI only in the inborn neonates. Conclusion Exposure to maternal HTN, especially preeclampsia/eclampsia superimposed on chronic HTN, was associated with less likelihood of early AKI in the inborn group. Key Points Maternal HTN is associated with less neonatal AKI. Maternal HTN category is variably associated with AKI. Inborn status is an important contributor to this association. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Late onset neonatal acute kidney injury: results from the AWAKEN Study

Author

Charlton, Jennifer R., Boohaker, Louis, Askenazi, David, Brophy, Patrick D., Fuloria, Mamta, Gien, Jason, Griffin, Russell, Hingorani, Sangeeta, Ingraham, Susan, Mian, Ayesa, Ohls, Robin K., Rastogi, Shantanu, Rhee, Christopher J., Revenis, Mary, Sarkar, Subrata, Starr, Michelle, Kent, Alison L., and on behalf of the Neonatal Kidney Collaborative (NKC)

Published
2019
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29. Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study

Author

Selewski, David T, Sarkar, Subrata, Kent, Alison, Fletcher, Jeffery, Abitbol, Carolyn L, DeFreitas, Marissa, Duara, Shahnaz, Charlton, Jennifer R, Guillet, Ronnie, D'Angio, Carl, Mian, Ayesa, Rademacher, Erin, Mhanna, Maroun J, Raina, Rupesh, Kumar, Deepak, Ambalavanan, Namasivayam, Arikan, Ayse Akcan, Rhee, Christopher J, Goldstein, Stuart L, Nathan, Amy T, Bhutada, Alok, Rastogi, Shantanu, Bonachea, Elizabeth, Ingraham, Susan, Mahan, John, Nada, Arwa, Brophy, Patrick D, Colaizy, Tarah T, Klein, Jonathan M, Cole, F Sessions, Davis, T Keefe, Dower, Joshua, Milner, Lawrence, Smith, Alexandra, Fuloria, Mamta, Reidy, Kimberly, Kaskel, Frederick J, Gien, Jason, Gist, Katja M, Hanna, Mina H, Hingorani, Sangeeta, Starr, Michelle, Joseph, Catherine, DuPont, Tara, Ohls, Robin, Staples, Amy, Khokhar, Surender, Perazzo, Sofia, Ray, Patricio E, Revenis, Mary, Synnes, Anne, Wintermark, Pia, Jetton, Jennifer G, Boohaker, Louis J, Sethi, Sidharth K, Wazir, Sanjay, Rohatgi, Smriti, Soranno, Danielle E, Chishti, Aftab S, Woroniecki, Robert, Mammen, Cherry, Swanson, Jonathan R, Sridhar, Shanthy, Wong, Craig S, Kupferman, Juan C, Griffin, Russell L, and Askenazi, David J

Published
2017
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31. Programs and processes for advancing pediatric acute kidney support therapy in hospitalized and critically ill children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference.

Author

Neumayr, Tara M., Bayrakci, Benan, Chanchlani, Rahul, Deep, Akash, Morgan, Jolyn, Arikan, Ayse Akcan, Basu, Rajit K., Goldstein, Stuart L., Askenazi, David J., Alobaidi, Rashid, Bagshaw, Sean M., Barhight, Matthew, Barreto, Erin, Ray II, O. N. Bignall, Bjornstad, Erica, Brophy, Patrick, Charlton, Jennifer, Conroy, Andrea L., Devarajan, Prasad, and Dolan, Kristin

Subjects
PROFESSIONAL practice, NEPHROTOXICOLOGY, EVALUATION of medical care, PATIENT aftercare, CRITICALLY ill, TRANSITIONAL care, PEDIATRICS, PATIENTS, WATER-electrolyte imbalances, CONFERENCES & conventions, EXTRACORPOREAL membrane oxygenation, MEDICAL care, INTELLECT, QUALITY assurance, TECHNOLOGY, REHABILITATION, ACUTE kidney failure, MEDICAL research, HOSPITAL care of children, CHILDREN
Abstract

Pediatric acute kidney support therapy (paKST) programs aim to reliably provide safe, effective, and timely extracorporeal supportive care for acutely and critically ill pediatric patients with acute kidney injury (AKI), fluid and electrolyte derangements, and/or toxin accumulation with a goal of improving both hospital-based and lifelong outcomes. Little is known about optimal ways to configure paKST teams and programs, pediatric-specific aspects of delivering high-quality paKST, strategies for transitioning from acute continuous modes of paKST to facilitate rehabilitation, or providing effective short- and long-term follow-up. As part of the 26th Acute Disease Quality Initiative Conference, the first to focus on a pediatric population, we summarize here the current state of knowledge in paKST programs and technology, identify key knowledge gaps in the field, and propose a framework for current best practices and future research in paKST. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Epidemiology of acute kidney injury in children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference.

Author

Sutherland, Scott M., Alobaidi, Rashid, Gorga, Stephen M., Iyengar, Arpana, Morgan, Catherine, Heydari, Emma, Arikan, A. Ayse Akcan, Basu, Raj K., Goldstein, Stuart L., Zappitelli, Michael, Askenazi, David J., Bagshaw, Sean M., Barhight, Matthew, Barreto, Erin, Bayrakci, Benan, Bignall II, O. N. Ray, Bjornstad, Erica, Brophy, Patrick, Charlton, Jennifer, and Chanchlani, Rahul

Subjects
ACUTE kidney failure prevention, BIOMARKERS, MIDDLE-income countries, SOCIAL determinants of health, SCHOLARLY method, CRITICALLY ill, DISEASE incidence, PATIENTS, MEDICAL care use, QUALITY assurance, LOW-income countries, QUALITY of life, ACUTE kidney failure, CHILDREN, ADOLESCENCE
Abstract

The nephrology and critical care communities have seen an increase in studies exploring acute kidney injury (AKI) epidemiology in children. As a result, we now know that AKI is highly prevalent in critically ill neonates, children, and young adults. Furthermore, children who develop AKI experience greater morbidity and higher mortality. Yet knowledge gaps still exist that suggest a more comprehensive understanding of AKI will form the foundation for future efforts designed to improve outcomes. In particular, the areas of community acquired AKI, AKI in non-critically ill children, and cohorts from low-middle income countries have not been well studied. Longer-term functional outcomes and patient-centric metrics including social determinants of health, quality of life, and healthcare utilization should be the foci of the next phase of scholarship. Current definitions identify AKI-based upon evidence of dysfunction which serves as a proxy for injury; biomarkers capable of identifying injury as it occurs are likely to more accurately define populations with AKI. Despite the strength of the association, the causal and mechanistic relationships between AKI and poorer outcomes remain inadequately examined. A more robust understanding of the relationship represents a potential to identify therapeutic targets. Once established, a more comprehensive understanding of AKI epidemiology in children will allow investigation of preventive, therapeutic, and quality improvement interventions more effectively. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Fluid assessment, fluid balance, and fluid overload in sick children: a report from the Pediatric Acute Disease Quality Initiative (ADQI) conference.

Author

Selewski, David T., Barhight, Matthew F., Bjornstad, Erica C., Ricci, Zaccaria, de Sousa Tavares, Marcelo, Akcan-Arikan, Ayse, Goldstein, Stuart L., Basu, Rajit, Bagshaw, Sean M., Alobaidi, Rashid, Askenazi, David J., Barreto, Erin, Bayrakci, Benan, Bignall II, O. N. Ray, Brophy, Patrick, Charlton, Jennifer, Chanchlani, Rahul, Conroy, Andrea L., Deep, Akash, and Devarajan, Prasad

Subjects
BODY fluid analysis, HYPERVOLEMIA, PROFESSIONS, WATER-electrolyte balance (Physiology), HEALTH care teams, RESEARCH funding, ACUTE diseases, CHILDREN
Abstract

Background: The impact of disorders of fluid balance, including the pathologic state of fluid overload in sick children has become increasingly apparent. With this understanding, there has been a shift from application of absolute thresholds of fluid accumulation to an appreciation of the intricacies of fluid balance, including the impact of timing, trajectory, and disease pathophysiology. Methods: The 26th Acute Disease Quality Initiative was the first to be exclusively dedicated to pediatric and neonatal acute kidney injury (pADQI). As part of the consensus panel, a multidisciplinary working group dedicated to fluid balance, fluid accumulation, and fluid overload was created. Through a search, review, and appraisal of the literature, summative consensus statements, along with identification of knowledge gaps and recommendations for clinical practice and research were developed. Conclusions: The 26th pADQI conference proposed harmonized terminology for fluid balance and for describing a pathologic state of fluid overload for clinical practice and research. Recommendations include that the terms daily fluid balance, cumulative fluid balance, and percent cumulative fluid balance be utilized to describe the fluid status of sick children. The term fluid overload is to be preserved for describing a pathologic state of positive fluid balance associated with adverse events. Several recommendations for research were proposed including focused validation of the definition of fluid balance, fluid overload, and proposed methodologic approaches and endpoints for clinical trials. [ABSTRACT FROM AUTHOR]

Published
2024
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34. A proposed framework for advancing acute kidney injury risk stratification and diagnosis in children: a report from the 26th Acute Disease Quality Initiative (ADQI) conference.

Author

Fuhrman, Dana Y., Stanski, Natalja L., Krawczeski, Catherine D., Greenberg, Jason H., Arikan, A. Ayse Akcan, Basu, Raj K., Goldstein, Stuart L., Gist, Katja M., Alobaidi, Rashid, Askenazi, David J., Bagshaw, Sean M., Barhight, Matthew, Barreto, Erin, Bayrakci, Benan, Ray Bignall II, O. N., Bjornstad, Erica, Brophy, Patrick, Charlton, Jennifer, Chanchlani, Rahul, and Conroy, Andrea L.

Subjects
ACUTE kidney failure prevention, BIOMARKERS, CLINICAL decision support systems, CONFERENCES & conventions, DISEASES, INDIVIDUALIZED medicine, RISK assessment, HEALTH literacy, QUALITY assurance, ACUTE kidney failure, PHENOTYPES, DISEASE risk factors, CHILDREN
Abstract

Acute kidney injury (AKI) in children is associated with increased morbidity, reduced health-related quality of life, greater resource utilization, and higher mortality. Improvements in the timeliness and precision of AKI diagnosis in children are needed. In this report, we highlight existing, novel, and on-the-horizon diagnostic and risk-stratification tools for pediatric AKI, and outline opportunities for integration into clinical practice. We also summarize pediatric-specific high-risk diagnoses and exposures for AKI, as well as the potential role of real-time risk stratification and clinical decision support to improve outcomes. Lastly, the key characteristics of important pediatric AKI phenotypes will be outlined. Throughout, we identify key knowledge gaps, which represent prioritized areas of focus for future research that will facilitate a comprehensive, timely and personalized approach to pediatric AKI diagnosis and management. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Receipt of high-frequency ventilation is associated with acute kidney injury in very preterm neonates.

Author

Haynes, Nicholas, Bell, Jeremiah, Griffin, Russel, Askenazi, David J., Jetton, Jennifer, Kent, Alison L., for the Neonatal Kidney Collaborative, Selewski, David T., Sarkar, Subrata, Fletcher, Jeffery, Abitbol, Carolyn L., DeFreitas, Marissa, Duara, Shahnaz, Charlton, Jennifer R., Swanson, Jonathan R., Guillet, Ronnie, D'Angio, Carl, Mian, Ayesa, Rademacher, Erin, and Mhanna, Maroun J.

Subjects
NEONATAL intensive care, CONFIDENCE intervals, NEONATAL diseases, RETROSPECTIVE studies, ACQUISITION of data, NEONATAL intensive care units, COMPARATIVE studies, RISK assessment, HIGH-frequency ventilation (Therapy), MEDICAL records, DESCRIPTIVE statistics, ACUTE kidney failure, LONGITUDINAL method, DISEASE risk factors
Abstract

Background: High-frequency ventilation (HFV) is frequently used in critically ill preterm neonates. We aimed to determine the incidence of acute kidney injury (AKI) in neonates less than 29 weeks gestation who received HFV in the first week of life and to determine if the rates of AKI differed in those who received other forms of respiratory support. Methods: This retrospective cohort study of 24 international, level III/IV neonatal intensive care units (NICUs) included neonates less than 29 weeks gestation from the AWAKEN study database. Exclusion criteria included the following: no intravenous fluids ≥ 48 h, admission ≥ 14 days of life, congenital heart disease requiring surgical repair at < 7 days of life, lethal chromosomal anomaly, death within 48 h, severe congenital kidney abnormalities, inability to determine AKI status, insufficient data on ventilation, and when the diagnosis of early AKI was unable to be made. Subjects were grouped into three groups based on ventilation modes (CPAP/no ventilation, conventional ventilation, and HFV). Results: The incidence of AKI was highest in the CPAP/no ventilation group, followed by HFV, followed by conventional ventilation (CPAP/no ventilation 48.5% vs. HFV 42.6% vs. conventional ventilation 28.4% (p = 0.009). An increased risk for AKI was found for those on HFV compared to CPAP/no ventilation (HR = 2.65; 95% CI:1.22–5.73). Conclusions: HFV is associated with AKI in the first week of life. Neonates on HFV should be screened for AKI. The reasons for this association are not clear. Further studies should evaluate the relationship between ventilator strategies and AKI in premature neonates. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Contributors

Author

Abbasi, Soraya, primary, Abbey, James, additional, Adzick, N. Scott, additional, Ahn, Sun-Young, additional, Albertine, Kurt H., additional, Allegaert, Karel, additional, Alper, Seth L., additional, Altit, Gabriel, additional, Altschuler, Steven M., additional, Alvaro, Ruben E., additional, Amorosa, Jennifer M.H., additional, Anbuhl, Kelsey L., additional, Andersen, Claus Yding, additional, Anderson, Richard A., additional, Askenazi, David J., additional, Auten, Richard Lambert, additional, Autmizguine, Julie, additional, Azhibekov, Timur, additional, Back, Stephen A., additional, Badaut, Jérôme, additional, Baker, Peter Russell, additional, Ballard, Philip L., additional, Bancalari, Eduardo H., additional, Barichello, Tatiana, additional, Battaglia, Frederick, additional, Baum, Michel, additional, Beggs, Simon, additional, Bell, Edward F., additional, Benchimol, Corinne, additional, Benders, Manon J.N.L., additional, Bennet, Laura, additional, Bennett, Phillip R., additional, Berger, Melvin, additional, Bernhard, Wolfgang, additional, Bertram, John F., additional, Bhosle, Vikrant K., additional, Bhutani, Vinod K., additional, Black, M. Jane, additional, Bliss, Joseph M., additional, Bolender, David L., additional, Brandenburg, Joline E., additional, Broussard, Delma L., additional, Brown, Laura Davidson, additional, Burrin, Douglas G., additional, Cannon, Barbara, additional, Caplan, Michael, additional, Carlson, Susan E., additional, Carlton, David P., additional, Caruana, Georgina, additional, Cashore, William J., additional, Chaemsaithong, Piya, additional, Chaiyasit, Noppadol, additional, Charlton, Jennifer R., additional, Cheatham, Carol L., additional, Chemtob, Sylvain, additional, Chen, Yi-Yung, additional, Chevalier, Robert L., additional, Chheda, Sadhana, additional, Childs, Andrew J., additional, Christensen, Robert D., additional, Chu, Alison, additional, Chu, David H., additional, Cilio, Maria Roberta, additional, Clark, David A., additional, Cleary-Goldman, Jane, additional, Clemente, Ethel G., additional, Clements, John A., additional, Clyman, Ronald I., additional, Cohen, Susan S., additional, Colombo, John, additional, Cowett, Richard M., additional, Crawford, Peter A., additional, Crowe, James E., additional, Cullen-McEwen, Luise A., additional, Cutfield, Wayne S., additional, D'Alton, Mary E., additional, Danzer, Enrico, additional, Delacourt, Christophe, additional, Devaskar, Sherin U., additional, Diacovo, Thomas G., additional, Docheva, Nikolina, additional, Dormans, John P., additional, Dysart, Kevin, additional, El-Khuffash, Afif, additional, Ellis, Peter James, additional, Empey, Kerry McGarr, additional, Ercal, Baris, additional, Erdős, Melinda, additional, Erickson, Robert P., additional, Fahim, Mohamed A., additional, Faksh, Arij, additional, Frank, Hans-Georg, additional, Friedlich, Philippe S., additional, Friedman, Jed, additional, Gao, Yuansheng, additional, Garland, Marianne, additional, Geddes, Donna, additional, Georgieff, Michael K., additional, Gien, Jason, additional, Giussani, Dino A., additional, Goldman, Armond S., additional, González, Efrén, additional, Good, Misty, additional, Grant, Denis M., additional, Green, Lucy R., additional, Grigoriou, Emmanouil, additional, Grimberg, Adda, additional, Gross, Ian, additional, Grunau, Ruth E., additional, Guignard, Jean-Pierre, additional, Gunn, Alistair Jan, additional, Gurtunca, Nursen, additional, Hadchouel, Alice, additional, Haddad, Gabriel G., additional, Hagberg, Henrik, additional, Hale, Thomas, additional, Hambidge, K. Michael, additional, Hammerman, Cathy, additional, Hansen, Thor Willy Ruud, additional, Hanson, Mark A., additional, Harding, Richard, additional, Harris, Mary Catherine, additional, Hartmann, Peter, additional, Hassiotou, Foteini, additional, Haugen, Guttorm, additional, Hawkes, Colin P., additional, Hay, William W., additional, Hayward, Christina E., additional, Heine, Vivi M., additional, Hellström, Ann, additional, Helmrath, Michael A., additional, Hendricks-Muñoz, Karen D., additional, Herrera, Emilio, additional, Hiatt, Michael J., additional, Hoath, Steven B., additional, Hooper, Stuart B., additional, Huang, Stephen A., additional, Iacobellli, Silvia, additional, Inder, Terrie E., additional, Iruela-Arispe, M. Luisa, additional, Jadcherla, Sudarshan R., additional, Jain, Deepak, additional, Jansson, Thomas, additional, Jefferies, John Lynn, additional, Jetton, Jennifer G., additional, Jobe, Alan H., additional, Johnson, Lois H., additional, Johnston, Richard B., additional, Jones, Rebecca Lee, additional, Jose, Pedro A., additional, Kalhan, Satish C., additional, Kallapur, Suhas G., additional, Kaplan, Michael, additional, Kaplan, Stanley, additional, Karpen, Heidi Eigenrauch, additional, Karpen, Saul J., additional, Karumanchi, S. Ananth, additional, Kaskel, Frederick J., additional, Katheria, Anup C., additional, Katz, Lorraine E. Levitt, additional, Keeney, Susan E., additional, Kern, Steven E., additional, Khanjani, Shirin, additional, Kilpatrick, Laurie E., additional, Kim, Chang-Ryul, additional, Kinsella, John P., additional, Kiserud, Torvid, additional, Koenig, Joyce M., additional, Kollmann, Tobias R., additional, Kolls, Jay K., additional, Krebs, Nancy F., additional, Kulik, Thomas J., additional, Kutikov, Jessica Katz, additional, Lakshminrusimha, Satyan, additional, Lamola, Angelo A., additional, Lasunción, Miguel Angel, additional, Lavoie, Pascal M., additional, LeBien, Tucker W., additional, Lee, Mary M., additional, Lee, Matthew K., additional, Lee, Yvonne K., additional, Leibel, Sandra, additional, Levine, Fred, additional, Levy, Ofer, additional, Liu, Yang, additional, Lobritto, Steven, additional, Loomis, Cynthia A., additional, Lopez, Colleen A., additional, MacIntyre, David A., additional, Mahe, Maxime M., additional, Maheshwari, Akhil, additional, Mankouski, Anastasiya, additional, Mantilla, Carlos B., additional, Marchant, Arnaud, additional, Margolis, Kara Gross, additional, Mariscalco, M. Michele, additional, Maródi, László, additional, Maršál, Karel, additional, Martin, Richard J., additional, Matsell, Douglas G., additional, Matthews, Dwight E., additional, McArdle, Harry J., additional, McManaman, James L., additional, McNamara, Patrick J., additional, McQuillen, Patrick S., additional, McQuinn, Tim C., additional, Mercer, Judith S., additional, Meschia, Giacomo, additional, Miller, Steven P., additional, Minoo, Parviz, additional, Monagle, Paul, additional, Mortola, Jacopo P., additional, Muglia, Louis J., additional, Munshi, Upender K., additional, Namgung, Ran, additional, Narasimhan, Sumana, additional, Nedergaard, Jan, additional, Neu, Josef, additional, Nigam, Sanjay K., additional, Nogee, Lawrence M., additional, Noori, Shahab, additional, O'Brien, Barbara M., additional, Ohls, Robin K., additional, Ortega-Senovilla, Henar, additional, O'Sullivan, Justin M., additional, Owusu, Sarah A., additional, Pal, Abhijeet, additional, Panitch, Howard B., additional, Penn, Anna A., additional, Penn, Raymond B., additional, Pernia, Cameron, additional, Philipps, Anthony F., additional, Picoraro, Joseph A., additional, Pisani, Francesco, additional, Pleasure, David, additional, Pleasure, Jeanette R., additional, Pleasure, Samuel J., additional, Pomeroy, Scott L., additional, Post, Martin, additional, Prakash, Y.S., additional, Prozialeck, Joshua D., additional, Pysher, Theodore J., additional, Quigley, Raymond, additional, Rabinovitch, Marlene, additional, Raffay, Thomas M., additional, Raj, J. Usha, additional, Ramsey, Haley, additional, Rana, Sarosh, additional, Randis, Tara Marie, additional, Ranger, Manon, additional, Ratner, Adam J., additional, Regnault, Timothy R.H., additional, Rigatto, Henrique, additional, Rintoul, Natalie E., additional, Romero, Roberto, additional, Rose, James C., additional, Rosenfeld, Charles R., additional, Ross, A. Catharine, additional, Rozycki, Henry J., additional, Ryan, Thomas D., additional, Sahni, Rakesh, additional, Sajti, Eniko, additional, Sarnat, Harvey B., additional, Satlin, Lisa M., additional, Saugstad, Ola Didrik, additional, Schierding, William, additional, Schmalstieg, Frank C., additional, Schwartz, George J., additional, Schwartz, Jeffrey, additional, Segar, Jeffrey L., additional, Selewski, David T., additional, Seri, Istvan, additional, Shaffer, Thomas H., additional, Shah, Kara N., additional, Shearer, Martin J., additional, Shojaie, Sharareh, additional, Shroyer, Noah F., additional, Sibley, Colin P., additional, Sieck, Gary C., additional, Simmons, Rebecca A., additional, Sivieri, Emidio M., additional, Smith, Francine G., additional, Smith, Lois E.H., additional, Smyth, Ian M., additional, Snarr, Brian S., additional, Snyder, Evan Y., additional, Sola-Visner, Martha, additional, Solhaug, Michael J., additional, Sperling, Mark A., additional, Srinivasan, Lakshmi, additional, Stahl, Andreas, additional, Stanley, Charles A., additional, Steinhorn, Robin H., additional, Stonestreet, Barbara S., additional, Strasburger, Janette F., additional, Styne, Dennis M., additional, Sussel, Lori, additional, Tam, Emily W.Y., additional, Tan, Libo, additional, Thornton, Claire, additional, Tollin, Daniel J., additional, Tóth, Beáta, additional, Towbin, Jeffrey A., additional, Trocle, Ashley, additional, Truog, William E., additional, Tsang, Reginald C., additional, Uhler, Kristin M., additional, Van Den Anker, John N., additional, van Goudoever, Johannes (Hans) B., additional, Vannucci, Susan J., additional, Vickers, Mark H., additional, Virgintino, Daniela, additional, Volpe, Joseph J., additional, Vora, Neeta L., additional, Vyas, Neha V., additional, Wacker-Gussmann, Annette, additional, Wallace, Megan J., additional, Walsh, Brian H., additional, Wang, Alice M., additional, Warburton, David, additional, Ward, Robert M., additional, Watterberg, Kristi L., additional, Werner, Lynne A., additional, Wershil, Barry K., additional, Wert, Susan E., additional, Wessels, Andy, additional, Whitsett, Jeffrey A., additional, Wise, Michael, additional, Wolf, Matthias T., additional, Wolfson, Marla R., additional, Wong, Hector R., additional, Wynn, James L., additional, Yeo, Lami, additional, Yip, Stephen, additional, Yoder, Bradley A, additional, Yoder, Mervin C., additional, Yoshimoto, Momoko, additional, Yuskaitis, Christopher J., additional, Zhou, Dan, additional, and Zovein, Ann, additional

Published
2017
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