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2. The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 2—global current practice patterns for the management of Cytomegalovirus anterior uveitis

Author

Thng, Zheng Xian, Putera, Ikhwanuliman, Testi, Ilaria, Chan, Kevin, Westcott, Mark, Chee, Soon-Phaik, Dick, Andrew D., Kempen, John H., Bodaghi, Bahram, Thorne, Jennifer E., Barisani-Asenbauer, Talin, de Smet, Marc D., Smith, Justine R., McCluskey, Peter, La Distia Nora, Rina, Jabs, Douglas A., de Boer, Joke H., Sen, H. Nida, Goldstein, Debra A., Khairallah, Moncef, Davis, Janet L., Rosenbaum, James T., Jones, Nicholas P., Nguyen, Quan Dong, Pavesio, Carlos, Agrawal, Rupesh, and Gupta, Vishali

Published
2024
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3. The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 1—global current practice patterns for the management of Herpes Simplex Virus and Varicella Zoster Virus anterior uveitis

Author

Thng, Zheng Xian, Putera, Ikhwanuliman, Testi, Ilaria, Chan, Kevin, Westcott, Mark, Chee, Soon-Phaik, Dick, Andrew D., Kempen, John H., Bodaghi, Bahram, Thorne, Jennifer E., Barisani-Asenbauer, Talin, de Smet, Marc D., Smith, Justine R., McCluskey, Peter, La Distia Nora, Rina, Jabs, Douglas A., de Boer, Joke H., Sen, H. Nida, Goldstein, Debra A., Khairallah, Moncef, Davis, Janet L., Rosenbaum, James T., Jones, Nicholas P., Nguyen, Quan Dong, Pavesio, Carlos, Agrawal, Rupesh, and Gupta, Vishali

Published
2024
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5. The Humira in Ocular Inflammations Taper (HOT) Study

Author

Pichi, Francesco, Smith, Scott D., Goldstein, Debra A., Baddar, Dina, Gerges, Terese K.A., Janetos, Timothy M., Ruiz-Cruz, Matilde, Elena Concha-del-Río, Luz, Maruyama, Kazuichi, Carina ten Berge, Josianne, Rombach, Saskia M., Cimino, Luca, Bolletta, Elena, Miserocchi, Elisabetta, Scandale, Pierluigi, Serafino, Massimiliano, Camicione, Paola, Androudi, Sofia, Gonzalez-Lopez, Julio J., Lim, Lyndell L., Singh, Nandini, Gupta, Vishali, Gupta, Nikita, Amer, Radgonde, Dodds, Emilio M., Inchauspe, Sebastian, Munk, Marion R., Donicova, Emilia, Carreño, Ester, Takeuchi, Masaru, Chee, Soon-Phaik, Chew, Milton C., Agarwal, Aniruddha, Schlaen, Ariel, Gómez, Ramiro A., Couto, Cristobal A., Khairallah, Moncef, and Neri, Piergiorgio

Published
2024
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7. Presentation, Diagnostic Testing and Initial Treatment of Vitreoretinal Lymphoma

Author

Androudi, Sofia, Apivatthakakul, Atitaya, Arevalo, Fernando J., Berkenstock, Meghan K., Carreño, Ester, Chee, Soon-Phaik, Choovuthayakorn, Janejit, Cimino, Luca, Cornish, Elisa E., Farrall, Alexandra L., Gehl, Zsuzsanna, Gentile, Pietro, Gerges, Terese K., Gozzi, Fabrizio, Hernández-Pons, Antonio, Issa, Samar, Kim, Hyeong Min, Kim, Min, Knickelbein, Jared E., Kunavisarut, Paradee, Lee, Seung M., Lim, Lyndell L., Lin, Ming Lee, Llorenç, Victor, López-Sierra, Sara, Martínez-Costa, Lucía, McCluskey, Peter, Mochizuki, Manabu, O'Day, Roderick F., Pai, Amy S., Palestine, Alan G., Pathanapitoon, Kessara, Radford, Mark H.B., Silpa-Archa, Sukhum, Smith, Justine R., Terada, Yukiko, Waduthantri, Samanthila, Weaver, Travers R.E., Williams, Keryn L., Woo, Se Joon, and Younan, Christine

Published
2024
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8. Severely subluxated cataract

Author

Chee, Soon-Phaik, primary, McKee, Yuri, additional, Snyder, Michael E., additional, Lockington, David, additional, Vasavada, Abhay, additional, Vasavada, Vaishali, additional, Daoud, Yassine J., additional, Rodgers, Emily Grace, additional, and Al-Mohtaseb, Zaina, additional

Published
2024
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11. Dengue Retinopathy

Author

Jap, Aliza, Mathur, Ranjana, Chee, Soon-Phaik, Gupta, Vishali, editor, Nguyen, Quan Dong, editor, LeHoang, Phuc, editor, and Agarwal, Aniruddha, editor

Published
2020
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12. Herpetic Anterior Uveitis

Author

Jap, Aliza, Chee, Soon-Phaik, Agarwal, Aniruddha, Gupta, Vishali, Gupta, Vishali, editor, Nguyen, Quan Dong, editor, LeHoang, Phuc, editor, and Agarwal, Aniruddha, editor

Published
2020
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19. Ultrasound biomicroscopy in the management of complex cataract and intraocular lens: A review.

Author

Chan, Nicole S.W., Lim, Jane S., Mohanram, Lakshmanasamudram S., and Chee, Soon‐Phaik

Subjects
ACOUSTIC microscopy, INTRAOCULAR lenses, PARS plana, CILIARY body, CATARACT
Abstract

Ultrasound biomicroscopy (UBM) is an invaluable investigation for imaging anterior segment structures. Although it is operator‐dependent and time consuming, unlike optical‐based imaging techniques, it is able to image structures posterior to the iris, such as the zonules, ciliary body and part of the pars plana. It is especially useful in advanced cataracts, traumatic cataracts, subluxed lenses, posterior polar cataracts, and congenital and developmental anomalies affecting the anterior segment. It provides diagnostic information in eyes with complex cataracts or intraocular lens (IOL)‐related pathology, and aids in surgical planning in order to minimise complications. In this review, we describe the UBM features of various lenticular pathologies and demonstrate its application in the diagnosis and surgical management of lens and IOL‐related pathologies. [ABSTRACT FROM AUTHOR]

Published
2024
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20. THE HUMIRA IN OCULAR INFLAMMATIONS TAPER (HOT) STUDY

Author

Pichi, Francesco, primary, Smith, Scott D, additional, Goldstein, Debra A, additional, Baddar, Dina, additional, Gerges, Terese K A, additional, Janetos, Timothy M, additional, Ruiz-Cruz, Matilde, additional, Concha-del-Río, Luz Elena, additional, Maruyama, Kazuichi, additional, Carina ten Berge, Josianne, additional, Rombach, Saskia M, additional, Cimino, Luca, additional, Bolletta, Elena, additional, Miserocchi, Elisabetta, additional, Scandale, Pierluigi, additional, Serafino, Massimiliano, additional, Camicione, Paola, additional, Androudi, Sofia, additional, Gonzalez-Lopez, Julio J, additional, Lim, Lyndell L., additional, Singh, Nandini, additional, Gupta, Vishali, additional, Gupta, Nikita, additional, Amer, Radgonde, additional, MD, Emilio M Dodds, additional, MD, Sebastian Inchauspe, additional, Munk, Marion R, additional, Donicova, Emilia, additional, Carreño, Ester, additional, Takeuchi, Masaru, additional, Chee, Soon-Phaik, additional, Chew, Milton C, additional, Agarwal, Aniruddha, additional, Schlaen, Ariel, additional, Gómez, Ramiro A, additional, Couto, Cristobal A., additional, Khairallah, Moncef, additional, and Neri, Piergiorgio, additional

Published
2023
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21. Antiviral treatment for acute retinal necrosis: A systematic review and meta-analysis

Author

Putera, Ikhwanuliman, primary, Ridwan, Asri Salima, additional, Dewi, Metta, additional, Cifuentes-González, Carlos, additional, Rojas-Carabali, William, additional, Sitompul, Ratna, additional, Edwar, Lukman, additional, Susiyanti, Made, additional, Aziza, Yulia, additional, Pavesio, Carlos, additional, Chee, Soon-Phaik, additional, Mahendradas, Padmamalini, additional, Biswas, Jyotirmay, additional, Kempen, John H., additional, Gupta, Vishali, additional, de-la-Torre, Alejandra, additional, Nora, Rina La Distia, additional, and Agrawal, Rupesh, additional

Published
2023
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28. Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract

Author

Yonova-Doing, Ekaterina, Zhao, Wanting, Igo, Jr, Robert P., Wang, Chaolong, Sundaresan, Periasamy, Lee, Kristine E., Jun, Gyungah R., Alves, Alexessander Couto, Chai, Xiaoran, Chan, Anita S. Y., Lee, Mei Chin, Fong, Allan, Tan, Ava G., Khor, Chiea Chuen, Chew, Emily Y., Hysi, Pirro G., Fan, Qiao, Chua, Jacqueline, Chung, Jaeyoon, Liao, Jiemin, Colijn, Johanna M., Burdon, Kathryn P., Fritsche, Lars G., Swift, Maria K., Hilmy, Maryam H., Chee, Miao Ling, Tedja, Milly, Bonnemaijer, Pieter W. M., Gupta, Preeti, Tan, Queenie S., Li, Zheng, Vithana, Eranga N., Ravindran, Ravilla D., Chee, Soon-Phaik, Shi, Yuan, Liu, Wenting, Su, Xinyi, Sim, Xueling, Shen, Yang, Wang, Ya Xing, Li, Hengtong, Tham, Yih-Chung, Teo, Yik Ying, Aung, Tin, Small, Kerrin S., Mitchell, Paul, Jonas, Jost B., Wong, Tien Yin, Fletcher, Astrid E., Klaver, Caroline C. W., Klein, Barbara E. K., Wang, Jie Jin, Iyengar, Sudha K., Hammond, Christopher J., and Cheng, Ching-Yu

Published
2020
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31. Risk factors affecting visual outcomes following dropped nucleus after cataract surgery

Author

Hu, Jeremy Youwei, Ti, Seng-Ei, and Chee, Soon-Phaik

Abstract

Background/ Aims: To describe the visual outcomes in eyes with dropped nucleus during phacoemulsification surgery. Setting: Singapore National Eye Centre (SNEC). Design: Retrospective chart review of prospectively reported cases of dropped nucleus. Methods: The clinical charts of all cases of dropped nucleus (Jan 2001 to Dec 2016) were retrospectively reviewed for patient demographics, surgeon type, stage of surgery, timing of pars plana vitrectomy (PPV), and complications. Visual success was defined as best corrected visual acuity (BCVA) ≥ 20/40 at last review. Final risk factors affecting visual success were identified using multivariate logistic regression analysis. Results: Incidence of dropped nucleus following cataract surgery was 0.17% (n= 292). Duration of follow-up was 25.5 months (mean), 18.5 months (median). There was a statistically significant difference in dropped nucleus rate between Residents (0.3%) and Faculty (0.14%) (x2= 38.2, P< 0.001), but ensuing major complications rates were similar. PPV was performed in 251 eyes (87.2%). At final examination, 202 cases (85.2%) achieved BCVA 20/40 or better, after excluding patients with co-existing ocular pathology. Timing of vitrectomy (delayed vs same-day) did not influence the final visual success (x2= 0.969, p= 0.51). Risk factors for poor visual outcomes included age >70 years, absence of intraocular lens (IOL) implant, and presence of major complications. Conclusion: Overall incidence of dropped nucleus in SNEC was 0.17%, with BCVA of 20/40 or better in 85.2% cases. Visual prognosis was influenced by patient’s age, presence of IOL implant or additional major complications.

Published
2024
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35. Association between obstructive sleep apnea and floppy eyelid syndrome: A systematic review and metaanalysis

Author

Cheong, Alex Jia Yang, primary, Ho, Owen Tsung Wen, additional, Wang, Sean Kang Xuan, additional, Woon, Chang Yi, additional, Yap, Kihan, additional, Ng, Kevin Joo Yang, additional, Xu, Flora Wen Xin, additional, See, Anna, additional, Ng, Adele Chin Wei, additional, Loh, Shaun Ray Han, additional, Chee, Soon-Phaik, additional, and Toh, Song Tar, additional

Published
2023
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36. Surgical decisions in the setting of zonulopathy

Author

Fram, Nicole R., primary, McKee, Yuri, additional, Chang, David F., additional, Chee, Soon-Phaik, additional, Donaldson, Kendall E., additional, Crandall, David A., additional, Al-Mohtaseb, Zaina, additional, and Chen, Allison J., additional

Published
2023
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38. Infectious Uveitis: Conversations with the Experts.

Author

Agrawal, Rupesh, Thng, Zheng Xian, Gupta, Amod, Toy, Brian C., Dick, Andrew D., Smith, Justine R., Chee, Soon-Phaik, Gupta, Vishali, and Rao, Narsing A.

Subjects
IRIDOCYCLITIS, UVEITIS, POSTERIOR segment (Eye), NUCLEOTIDE sequencing, IDIOPATHIC thrombocytopenic purpura, GENE expression
Abstract

Isolated ocular infections that currently require systemic therapy or prophylaxis, such as viral infections, toxoplasmosis, and certain cases of tuberculous uveitis for example, would greatly benefit from long-lasting local drug delivery systems. Local ocular therapies nevertheless can play a role in patients who are unable to tolerate systemic treatment (i.e., pancytopenia as a side effect of ganciclovir treatment). In general, if I see a role for anti-inflammatory treatment with systemic prednisolone - for example, in toxoplasmic retinochoroiditis - I like to see a response to the antimicrobial drug(s) or at least allow time for antimicrobial therapy to have had sufficient time to take effect before starting prednisolone, and I watch carefully to ensure there is no progression after starting this agent. B SPC b :Generally, I prefer to start the antimicrobial therapy 48-72 hours ahead of the corticosteroid/immunomodulatory therapy to allow time for the former to take effect. In a nutshell, sometimes stop the current treatment, re-analyse the case for potential differentials that might have been overlooked, and if none, then start appropriately and slowly increase immunosuppressive therapy (under cover of antimicrobials). B AG b :Traditionally, CMV retinitis was seen in patients with HIV infection and manifested as a perivascular chronic retinitis that progressed rather slowly and was accompanied by minimal anterior chamber or vitreous reaction. [Extracted from the article]

Published
2023
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39. Ocular Toxoplasmosis.

Author

Goh, Eunice Jin Hui, Putera, Ikhwanuliman, La Distia Nora, Rina, Mahendradas, Padmamalini, Biswas, Jyotirmay, Chee, Soon-Phaik, Testi, Ilaria, Pavesio, Carlos E, Curi, Andre Luiz Land, Vasconcelos-Santos, Daniel Vitor, Arora, Atul, Gupta, Vishali, de-la-Torre, Alejandra, and Agrawal, Rupesh

Subjects
TOXOPLASMOSIS, IRIDOCYCLITIS, VISION disorders, LITERARY sources, AGE groups, UVEITIS
Abstract

Introduction: Ocular toxoplasmosis is the leading cause of posterior uveitis worldwide, affecting individuals acrossdifferent age groups. The key to reducing vision loss includes prompt diagnosis and treatment. However, despite the prevalence of ocular toxoplasmosis, there has been little consensus regarding its pathophysiology,clinical features, diagnosis, and especially management. Methods: The data sources were literature reviews, including Pub Med and Medline databases. Search terms included toxoplasmosis, retinitis, vasculitis, vitritis, uveitis alone or in combination with, serum, aqueous, vitreous eye, ocular and review. Results: In this review paper, we have sought to provide an overview of the pathophysiology, epidemiology, and clinical features of the disease, both based on current literature and our own clinical experience. We have also discussed the use of serology, ocular fluid, and ophthalmic investigations that could further facilitate the diagnosis of ocular toxoplasmosis.Different management strategies have been reported worldwide, including newer approaches such as local therapy. Conclusion: A better understanding of critical aspects of ocular toxoplasmosis will hopefully lead to reduced morbidity, including blindness associated with this condition. [ABSTRACT FROM AUTHOR]

Published
2023
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41. Infectious Uveitis: Conversations with the Experts

Author

Agrawal, Rupesh, primary, Thng, Zheng Xian, additional, Gupta, Amod, additional, Toy, Brian C., additional, Dick, Andrew D., additional, Smith, Justine R, additional, Chee, Soon-Phaik, additional, Gupta, Vishali, additional, and Rao, Narsing A., additional

Published
2022
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42. Ocular Toxoplasmosis

Author

Goh, Eunice Jin Hui, primary, Putera, Ikhwanuliman, additional, La Distia Nora, Rina, additional, Mahendradas, Padmamalini, additional, Biswas, Jyotirmay, additional, Chee, Soon-Phaik, additional, Testi, Ilaria, additional, Pavesio, Carlos E, additional, Curi, Andre Luiz Land, additional, Vasconcelos-Santos, Daniel Vitor, additional, Arora, Atul, additional, Gupta, Vishali, additional, de-la-Torre, Alejandra, additional, and Agrawal, Rupesh, additional

Published
2022
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43. Clinical characteristics and treatment outcomes of cytomegalovirus anterior uveitis and endotheliitis: A systematic review and meta-analysis

Author

La Distia Nora, Rina, primary, Putera, Ikhwanuliman, additional, Mayasari, Yuri Dwi, additional, Hikmahwati, Wandya, additional, Pertiwi, Adinda Mulya, additional, Ridwan, Asri Salima, additional, Sitompul, Ratna, additional, Westcott, Mark, additional, Chee, Soon-Phaik, additional, Pavesio, Carlos, additional, Thng, Zheng Xian, additional, Gupta, Vishali, additional, and Agrawal, Rupesh, additional

Published
2022
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48. Viral anterior uveitis

Author

Babu, Kalpana, Konana, Vinaya, Ganesh, Sudha, Patnaik, Gazal, Chan, Nicole, Chee, Soon-Phaik, Sobolewska, Bianka, and Zierhut, Manfred

Subjects
Ophthalmic research, Virus diseases -- Diagnosis -- Care and treatment, Uveitis -- Diagnosis -- Care and treatment, Health
Abstract

Byline: Kalpana. Babu, Vinaya. Konana, Sudha. Ganesh, Gazal. Patnaik, Nicole. Chan, Soon-Phaik. Chee, Bianka. Sobolewska, Manfred. Zierhut Viral anterior uveitis (VAU) needs to be suspected in anterior uveitis (AU) associated [...]

Published
2020

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