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569 results on '"Chen, Andrew C."'

1. Pain

Author

Chen, Jun, Han, Ji-Sheng, Zhao, Zhi-Qi, Wei, Feng, Hsieh, Jen-Chuen, Bao, Lan, Chen, Andrew C. N., Dai, Yi, Fan, Bi-Fa, Gu, Jian-Guo, Hao, Shuang-Lin, Hu, San-Jue, Ji, Yong-Hua, Li, Yong-Jie, Li, Yun-Qing, Lin, Qing, Liu, Xian-Guo, Liu, Yan-Qing, Lu, Yan, Luo, Fei, Ma, Chao, Qiu, Yun-Hai, Rao, Zhi-Ren, Shi, Lin, Shyu, Bai-Chuang, Song, Xue-Jun, Tang, Jing-Shi, Tao, Yuan-Xiang, Wan, You, Wang, Jia-Shuang, Wang, Ke-Wei, Wang, Yun, Xu, Guang-Yin, Xu, Tian-Le, You, Hao-Jun, Yu, Long-Chuan, Yu, Sheng-Yuan, Zhang, Da-Ying, Zhang, De-Ren, Zhang, Jun-Ming, Zhang, Xu, Zhang, Yu-Qiu, Zhuo, Min, Pfaff, Donald W., editor, Volkow, Nora D., editor, and Rubenstein, John L., editor

Published
2022
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5. Pain

Author

Chen, Jun, Han, Ji-Sheng, Zhao, Zhi-Qi, Wei, Feng, Hsieh, Jen-Chuen, Bao, Lan, Chen, Andrew C. N., Dai, Yi, Fan, Bi-Fa, Gu, Jian-Guo, Hao, Shuang-Lin, Hu, San-Jue, Ji, Yong-Hua, Li, Yong-Jie, Li, Yun-Qing, Lin, Qing, Liu, Xian-Guo, Liu, Yan-Qing, Lu, Yan, Luo, Fei, Ma, Chao, Qiu, Yun-Hai, Rao, Zhi-Ren, Shi, Lin, Shyu, Bai-Chuang, Song, Xue-Jun, Tang, Jing-Shi, Tao, Yuan-Xiang, Wan, You, Wang, Jia-Shuang, Wang, Ke-Wei, Wang, Yun, Xu, Guang-Yin, Xu, Tian-Le, You, Hao-Jun, Yu, Long-Chuan, Yu, Sheng-Yuan, Zhang, Da-Ying, Zhang, De-Ren, Zhang, Jun-Ming, Zhang, Xu, Zhang, Yu-Qiu, Zhuo, Min, Pfaff, Donald W., editor, and Volkow, Nora D., editor

Published
2016
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7. Nicotinamide for Skin-Cancer Chemoprevention in Transplant Recipients

Author

Allen, Nicholas C., primary, Martin, Andrew J., additional, Snaidr, Victoria A., additional, Eggins, Renee, additional, Chong, Alvin H., additional, Fernandéz-Peñas, Pablo, additional, Gin, Douglas, additional, Sidhu, Shireen, additional, Paddon, Vanessa L., additional, Banney, Leith A., additional, Lim, Adrian, additional, Upjohn, Edward, additional, Schaider, Helmut, additional, Ganhewa, Aparna D., additional, Nguyen, Jennifer, additional, McKenzie, Catriona A., additional, Prakash, Saurabh, additional, McLean, Catriona, additional, Lochhead, Alistair, additional, Ibbetson, Jan, additional, Dettrick, Andrew, additional, Landgren, Anthony, additional, Allnutt, Katherine J., additional, Allison, Clare, additional, Davenport, Rachael B., additional, Mumford, Blake P., additional, Wong, Brittany, additional, Stagg, Brendan, additional, Tedman, Alexander, additional, Gribbin, Hannah, additional, Edwards, Harrison A., additional, De Rosa, Nicholas, additional, Stewart, Thomas, additional, Doolan, Brent J., additional, Kok, Yonatan, additional, Simpson, Kate, additional, Low, Zhi M., additional, Kovitwanichkanont, Tom, additional, Scolyer, Richard A., additional, Dhillon, Haryana M., additional, Vardy, Janette L., additional, Chadban, Steven J., additional, Bowen, David G., additional, Chen, Andrew C., additional, and Damian, Diona L., additional

Published
2023
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8. Splice-Site Variants in the Gene Encoding GABA-A Receptor Delta Subunit Are Associated with Amphetamine Use in Patients under Methadone Maintenance Treatment

Author

Lin, Yen-Feng, primary, Chou, Wen-Hai, additional, Liu, Tung-Hsia, additional, Fang, Chiu-Ping, additional, Kuo, Hsiang-Wei, additional, Kuo, Po-Hsiu, additional, Tsai, Shih-Jen, additional, Wang, Sheng-Chang, additional, Chung, Ren-Hua, additional, Tsou, Hsiao-Hui, additional, Chen, Andrew C. H., additional, and Liu, Yu-Li, additional

Published
2022
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10. A Randomized Clinical Trial of Naltrexone and Behavioral Therapy for Problem Drinking Men Who Have Sex with Men

Author

Morgenstern, Jon, Kuerbis, Alexis N., and Chen, Andrew C.

Abstract

Objective: This study tested the comparative effectiveness of modified behavioral self-control therapy (MBSCT) and naltrexone (NTX), as well as the added benefit of combining the 2, in problem drinking men who have sex with men (MSM) seeking to reduce but not quit drinking. Method: Participants (N = 200) were recruited and urn randomized to 1 of 2 medication conditions, NTX or placebo (PBO), and either MSBCT or no behavioral intervention, yielding 4 conditions: PBO, NTX, MSBCT, and NTX + MSBCT. In addition, all participants received a brief medication compliance intervention. Participants were treated for 12 weeks and assessed 1 week after treatment completion. Two primary outcomes--sum of standard drinks and number of heavy drinking days--and 1 secondary outcome-percentage of those drinking in a nonhazardous manner (NoH)--were selected a priori. Results: There was a significant main effect for MBSCT (all ps less than 0.01) but not NTX on all 3 outcomes. In addition, the combination of NTX and MBSCT was not more effective than either MSCBT or PBO. There was a significant interaction effect on NoH, such that NTX significantly increased the likelihood (odds ratio = 3.3) of achieving a nonhazardous drinking outcome relative to PBO. In addition, NTX was significantly more effective than PBO on a descriptive outcome: negative consequences of drinking. Conclusions: There was no advantage to adding NTX to MBSCT. In addition, MBSCT showed stronger evidence of efficacy than NTX. At the same time, NTX delivered in the context of a minimal medication compliance intervention was significantly more effective than PBO on an important clinical indicator. Results provide new information to guide the treatment of problem drinking, including in primary care settings. (Contains 2 tables and 3 figures.)

Published
2012
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12. Splice-Site Variants in the Gene Encoding GABA-A Receptor Delta Subunit Are Associated with Amphetamine Use in Patients under Methadone Maintenance Treatment.

Author

Lin, Yen-Feng, Chou, Wen-Hai, Liu, Tung-Hsia, Fang, Chiu-Ping, Kuo, Hsiang-Wei, Kuo, Po-Hsiu, Tsai, Shih-Jen, Wang, Sheng-Chang, Chung, Ren-Hua, Tsou, Hsiao-Hui, Chen, Andrew C. H., and Liu, Yu-Li

Subjects
METHADONE treatment programs, GABA receptors, GENETIC variation, AMPHETAMINES, OPIOID abuse, SARS-CoV-2 Delta variant
Abstract

Chronic opioid use disorder patients often also use other substances such as amphetamines. The gene-based analysis method was applied in the genomic database obtained from our previous study with 343 methadone maintenance treatment (MMT) patients. We found that the gene encoding gamma-aminobutyric acid type A receptors (GABA-A receptor) delta subunit isoforms (GABRD) was associated with amphetamine use in heroin dependent patients under MMT in Taiwan. A total of 15% of the 343 MMT patients tested positive for amphetamine in the urine toxicology test. Two genetic variants in the GABRD, rs2889475 and rs2376805, were found to be associated with the positive urine amphetamine test. They are located in the exon 1 of the splice variant and altered amino acid compositions (T126I, C/T, for rs2889475, and R252Q, G/A, for rs2376805). The CC genotype carriers of rs2889475 showed a four times higher risk of amphetamine use than those with TT genotype. The GG genotype carriers of rs2376805 showed a three times higher risk of amphetamine use than the AA genotype carriers. To our knowledge, this is the first report that demonstrated an association of the delta splice variant isoform in the GABA-A receptor with an increased risk of amphetamine use in MMT patients. Our results suggest that rs2889475 and rs2376805 may be indicators for the functional role and risk of amphetamine use in MMT patients. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Single-Nucleotide Polymorphisms in Corticotropin Releasing Hormone Receptor 1 Gene (CRHR1) Are Associated With Quantitative Trait of Event-Related Potential and Alcohol Dependence

Author

Chen, Andrew C. H., Manz, Niklas, Tang, Yongqiang, Rangaswamy, Madhavi, Almasy, Laura, Kuperman, Samuel, Nurnberger, John, Jr, OʼConnor, Sean J., Edenberg, Howard J., Schuckit, Marc A., Tischfield, Jay, Foroud, Tatiana, Bierut, Laura J., Rohrbaugh, John, Rice, John P., Goate, Alison, Hesselbrock, Victor, and Porjesz, Bernice

Published
2010
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43. The valuation of PBGC insurance premiums using an option pricing model

Author

Hsieh, Su-Jane, Chen, Andrew C., and Ferris, Kenneth R.

Subjects
United States. Pension Benefit Guaranty Corp. -- Analysis, Pension funds -- Analysis, Insurance -- Analysis, Options (Finance) -- Analysis, Banking, finance and accounting industries, Business
Published
1994

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