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2. Usability of Food Size Aids in Mobile Dietary Reporting Apps for Young Adults: Randomized Controlled Trial

Author

Liu, Ying-Chieh, Wu, Sheng-Tang, Lin, Shan-Ju, Chen, Chien-Hung, Lin, Yu-Sheng, and Chen, Hsin-Yun

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundYoung adults are more likely to use self-managed dietary reporting apps. However, there is scant research examining the user experience of different measurement approaches for mobile dietary reporting apps when dealing with a wide variety of food shapes and container sizes. ObjectiveField user experience testing was conducted under actual meal conditions to assess the accuracy, efficiency, and subjective reaction of three food portion measurement methods embedded in a developed mobile app. Key-in–based aid (KBA), commonly used in many current apps, relies on the user’s ability to key in volumes or weights. Photo-based aid (PBA) extends traditional assessment methods, allowing users to scroll, observe, and select a reduced-size image from a set of options. Gesture-based aid (GBA) is a new experimental approach in which the user makes finger movements on the screen to roughly describe food portion boundaries accompanied by a background reference. MethodsA group of 124 young adults aged 19 to 26 years was recruited for a head-to-head randomized comparison and divided into 3 groups: a KBA (n=42) control group and PBA (n=41) and GBA (n=41) experimental groups. In total, 3 meals (ie, breakfast, lunch, and dinner) were served in a university cafeteria. Participants were provided with 25 dishes and beverages for selection, with a variety of food shapes and containers that reflect everyday life conditions. The accuracy of and time spent on realistic interaction during food portion estimation and the subjective reaction of each aid were recorded and analyzed. ResultsParticipants in the KBA group provided the highest accuracy in terms of hash brown weight (P=.004) and outperformed PBA or GBA for many soft drinks in cups. PBA had the best results for a cylindrical hot dog (P

Published
2020
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3. Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan

Author

Chang, Chin-Wei, Hsu, Wei-Fan, Tseng, Kuo-Chih, Chen, Chi-Yi, Cheng, Pin-Nan, Hung, Chao-Hung, Lo, Ching-Chu, Bair, Ming-Jong, Chen, Chien-Hung, Lee, Pei-Lun, Lin, Chun-Yen, Kuo, Hsing-Tao, Chen, Chun-Ting, Yang, Chi-Chieh, Huang, Jee-Fu, Tai, Chi-Ming, Hu, Jui-Ting, Lin, Chih-Lang, Su, Wei-Wen, Tsai, Wei-Lun, Huang, Yi-Hsiang, Cheng, Chien-Yu, Lin, Chih-Lin, Wang, Chia-Chi, Yang, Sheng-Shun, Mo, Lein-Ray, Chen, Guei-Ying, Chang, Chun-Chao, Wang, Szu-Jen, Huang, Chia-Sheng, Hsieh, Tsai-Yuan, Lin, Chih-Wen, Lee, Tzong-Hsi, Chong, Lee-Won, Huang, Chien-Wei, Chang, Shiuh-Nan, Tsai, Ming-Chang, Hsu, Shih-Jer, Kao, Jia-Horng, Liu, Chun-Jen, Liu, Chen-Hua, Lin, Han-Chieh, Tsai, Pei-Chien, Yeh, Ming-Lun, Huang, Chung-Feng, Dai, Chia-Yen, Chuang, Wan-Long, Yu, Ming-Lung, and Peng, Cheng-Yuan

Published
2024
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8. Evaluating Mobile Health Apps for Customized Dietary Recording for Young Adults and Seniors: Randomized Controlled Trial

Author

Liu, Ying-Chieh, Chen, Chien-Hung, Tsou, Ya-Chi, Lin, Yu-Sheng, Chen, Hsin-Yun, Yeh, Jou-Yin, and Chiu, Sherry Yueh-Hsia

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundThe role of individual-tailored dietary recording in mobile phone health apps has become increasingly important in management of self-health care and population-based preventive service. The development of such mobile apps for user-centered designing is still challengeable and requires further scientific evidence. ObjectiveThis study aims to conduct a randomized trial to assess the accuracy and time efficiency of two prototypes for dietary recoding utilization related to the input method of food intake. MethodsWe first present an innovative combinatorial concept for dietary recording to account for dish variation. One prototype was a self-chosen tab app that featured choosing each food ingredient to synthesize an individual dish, whereas the other was an autonomous exhaustive list app that provided one selection from a comprehensive list of dish items. The concept included commercially available choices that allowed users to more accurately account for their individual food selection. The two mobile apps were compared in a head-to-head parallel randomized trial evaluation. Young adults (n=70, aged 18-29) and older adults (n=35, aged 55-73) were recruited and randomized into two groups for accuracy and response time evaluation based on 12 types of food items in use of the developed self-chosen tab and autonomous exhaustive list apps, respectively. ResultsFor the trials based on the self-chosen tab (53 participants) and autonomous exhaustive list groups (52 participants), the two prototypes were found to be highly accurate (>98%). The self-chosen tab app was found to be more efficient, requiring significantly less time for input of 11 of 12 items (P

Published
2019
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11. Baseline Viral Load and On-Treatment Hepatocellular Carcinoma Risk in Chronic Hepatitis B: A Multinational Cohort Study

Author

Choi, Won-Mook, Yip, Terry Cheuk-Fung, Wong, Grace Lai-Hung, Kim, W. Ray, Yee, Leland J., Brooks-Rooney, Craig, Curteis, Tristan, Clark, Laura J., Jafry, Zarena, Chen, Chien-Hung, Chen, Chi-Yi, Huang, Yi-Hsiang, Jin, Young-Joo, Jun, Dae Won, Kim, Jin-Wook, Park, Neung Hwa, Peng, Cheng-Yuan, Shin, Hyun Phil, Shin, Jung Woo, Yang, Yao-Hsu, and Lim, Young-Suk

Published
2025
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13. Predictors of hepatic flares after nucleos(t)ide analogue cessation – Results of a global cohort study (RETRACT-B study)

Author

Dongelmans, Edo J., Hirode, Grishma, Hansen, Bettina E., Chen, Chien-Hung, Su, Tung-Hung, Seto, Wai-Kay, Furquim d'Almeida, Arno, van Hees, Stijn, Papatheodoridi, Margarita, Lens, Sabela, Wong, Grace L.H., Brakenhoff, Sylvia M., Chien, Rong-Nan, Feld, Jordan J., Chan, Henry L.Y., Forns, Xavier, Papatheodoridis, George V., Vanwolleghem, Thomas, Yuen, Man-Fung, Hsu, Yao-Chun, Kao, Jia-Horng, Cornberg, Markus, Sonneveld, Milan J., Jeng, Wen-Juei, and Janssen, Harry L.A.

Published
2025
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15. Switching to tenofovir alafenamide in patients with virologically suppressed chronic hepatitis B and renal or hepatic impairment: final week 96 results from an open-label, multicentre, phase 2 study

Author

Janssen, Harry L A, Lim, Young-Suk, Lampertico, Pietro, Heo, Jeong, Chen, Chi-Yi, Fournier, Claire, Tsang, Tak Yin Owen, Bae, Ho, Chen, Chien-Hung, Coffin, Carla S, Ahn, Sang Hoon, Trinh, Huy, Flaherty, John F, Abramov, Frida, Zhao, Yang, Liu, Yang, Lau, Audrey, German, Polina, Chuang, Wan-Long, Agarwal, Kosh, and Gane, Edward

Published
2024
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17. HBV DNA and HBsAg Levels at 24 Weeks Off-Treatment Predict Clinical Relapse and HBsAg Loss in HBeAg-Negative Patients Who Discontinued Antiviral Therapy

Author

Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, Colombatto, Piero, van Bömmel, Florian, Janssen, Harry L., Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Brunetto, Maurizia, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, and Maasoumy, Benjamin

Published
2024
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20. IMMVP: An Efficient Daytime and Nighttime On-Road Object Detector

Author

Wu, Cheng-En, Chan, Yi-Ming, Chen, Chien-Hung, Chen, Wen-Cheng, and Chen, Chu-Song

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Multimedia
Abstract

It is hard to detect on-road objects under various lighting conditions. To improve the quality of the classifier, three techniques are used. We define subclasses to separate daytime and nighttime samples. Then we skip similar samples in the training set to prevent overfitting. With the help of the outside training samples, the detection accuracy is also improved. To detect objects in an edge device, Nvidia Jetson TX2 platform, we exert the lightweight model ResNet-18 FPN as the backbone feature extractor. The FPN (Feature Pyramid Network) generates good features for detecting objects over various scales. With Cascade R-CNN technique, the bounding boxes are iteratively refined for better results., Comment: Accepted at IEEE 21st International Workshop on Multimedia Signal Processing (MMSP 2019)

Published
2019

21. Compacting, Picking and Growing for Unforgetting Continual Learning

Author

Hung, Steven C. Y., Tu, Cheng-Hao, Wu, Cheng-En, Chen, Chien-Hung, Chan, Yi-Ming, and Chen, Chu-Song

Subjects
Computer Science - Machine Learning, Statistics - Machine Learning
Abstract

Continual lifelong learning is essential to many applications. In this paper, we propose a simple but effective approach to continual deep learning. Our approach leverages the principles of deep model compression, critical weights selection, and progressive networks expansion. By enforcing their integration in an iterative manner, we introduce an incremental learning method that is scalable to the number of sequential tasks in a continual learning process. Our approach is easy to implement and owns several favorable characteristics. First, it can avoid forgetting (i.e., learn new tasks while remembering all previous tasks). Second, it allows model expansion but can maintain the model compactness when handling sequential tasks. Besides, through our compaction and selection/expansion mechanism, we show that the knowledge accumulated through learning previous tasks is helpful to build a better model for the new tasks compared to training the models independently with tasks. Experimental results show that our approach can incrementally learn a deep model tackling multiple tasks without forgetting, while the model compactness is maintained with the performance more satisfiable than individual task training., Comment: To appear in NeurIPS 2019

Published
2019

23. Lower pretreatment HBV DNA levels are associated with better off-treatment outcomes after nucleo(s)tide analogue withdrawal in patients with HBeAg-negative chronic hepatitis B: A multicentre cohort study

Author

Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, Colombatto, Piero, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Brunetto, Maurizia, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, and Maasoumy, Benjamin

Published
2023
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25. Differential Relapse Patterns After Discontinuation of Entecavir vs Tenofovir Disoproxil Fumarate in Chronic Hepatitis B

Author

Choi, Hannah S.J., Hirode, Grishma, Chen, Chien-Hung, Su, Tung-Hung, Seto, Wai-Kay, Van Hees, Stijn, Papatheodoridi, Margarita, Lens, Sabela, Wong, Grace L.H., Brakenhoff, Sylvia M., Chien, Rong-Nan, Feld, Jordan J., Sonneveld, Milan J., Chan, Henry L.Y., Forns, Xavier, Papatheodoridis, George V., Vanwolleghem, Thomas, Yuen, Man-Fung, Hsu, Yao-Chun, Kao, Jia-Horng, Cornberg, Markus, Hansen, Bettina E., Jeng, Wen-Juei, and Janssen, Harry L.A.

Published
2023
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26. Effectiveness of entecavir vs tenofovir disoproxil fumarate for functional cure of chronic hepatitis B in an international cohort

Author

Hsu, Yao-Chun, Jun, Dae Won, Peng, Cheng-Yuan, Yeh, Ming-Lun, Trinh, Huy, Wong, Grace Lai-Hung, Kim, Sung Eun, Chen, Chien-Hung, Oh, Hyunwoo, Lin, Chia-Hsin, Trinh, Lindsey, Wong, Vincent Wai-Sun, Yoon, Eilleen, Ahn, Sang Bong, Huang, Daniel, Cho, Yong Kyun, Jeong, Jae Yoon, Jeong, Soung Won, Kim, Hyoung Su, Xie, Qing, Liu, Li, Riveiro-Barciela, Mar, Tsai, Pei-Chien, Accarino, Elena Vargas, Toyoda, Hidenori, Enomoto, Masaru, Preda, Carmen, Marciano, Sebastián, Hoang, Joseph, Huang, Chung-Feng, Kozuka, Ritsuzo, Yasuda, Satoshi, Istratescu, Doina, Lee, Dong-Hyun, Su, Jia-Ying, Huang, Yen-Tsung, Huang, Jee Fu, Dai, Chia-Yen, Chuang, Wan-Long, Yuen, Man-Fung, Gadano, Adrian, Cheung, Ramsey, Lim, Seng Gee, Buti, Maria, Yu, Ming-Lung, and Nguyen, Mindie H.

Published
2022
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27. Hepatocellular carcinoma risk in patients with chronic hepatitis B receiving tenofovir- vs. entecavir-based regimens: Individual patient data meta-analysis

Author

Choi, Won-Mook, Yip, Terry Cheuk-Fung, Wong, Grace Lai-Hung, Kim, W. Ray, Yee, Leland J., Brooks-Rooney, Craig, Curteis, Tristan, Cant, Harriet, Chen, Chien-Hung, Chen, Chi-Yi, Huang, Yi-Hsiang, Jin, Young-Joo, Jun, Dae Won, Kim, Jin-Wook, Park, Neung Hwa, Peng, Cheng-Yuan, Shin, Hyun Phil, Shin, Jung Woo, Yang, Yao-Hsu, and Lim, Young-Suk

Published
2023
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31. Stingray Detection of Aerial Images Using Augmented Training Images Generated by A Conditional Generative Model

Author

Chou, Yi-Min, Chen, Chien-Hung, Liu, Keng-Hao, and Chen, Chu-Song

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

In this paper, we present an object detection method that tackles the stingray detection problem based on aerial images. In this problem, the images are aerially captured on a sea-surface area by using an Unmanned Aerial Vehicle (UAV), and the stingrays swimming under (but close to) the sea surface are the target we want to detect and locate. To this end, we use a deep object detection method, faster RCNN, to train a stingray detector based on a limited training set of images. To boost the performance, we develop a new generative approach, conditional GLO, to increase the training samples of stingray, which is an extension of the Generative Latent Optimization (GLO) approach. Unlike traditional data augmentation methods that generate new data only for image classification, our proposed method that mixes foreground and background together can generate new data for an object detection task, and thus improve the training efficacy of a CNN detector. Experimental results show that satisfiable performance can be obtained by using our approach on stingray detection in aerial images., Comment: to appear in CVPR 2018 Workshop (CVPR 2018 Workshop and Challenge: Automated Analysis of Marine Video for Environmental Monitoring)

Published
2018

39. Ledipasvir/sofosbuvir for HCV genotype 1, 2, 4–6 infection: Real-world evidence from a nationwide registry in Taiwan

Author

Lo, Ching-Chu, Huang, Chung-Feng, Cheng, Pin-Nan, Tseng, Kuo-Chih, Chen, Chi-Yi, Kuo, Hsing-Tao, Huang, Yi-Hsiang, Tai, Chi-Ming, Peng, Cheng-Yuan, Bair, Ming-Jong, Chen, Chien-Hung, Yeh, Ming-Lun, Lin, Chih-Lang, Lin, Chun-Yen, Lee, Pei-Lun, Chong, Lee-Won, Hung, Chao-Hung, Chang, Te Sheng, Huang, Jee-Fu, Yang, Chi-Chieh, Hu, Jui-Ting, Lin, Chih-Wen, Chen, Chun-Ting, Wang, Chia-Chi, Su, Wei-Wen, Hsieh, Tsai-Yuan, Lin, Chih-Lin, Tsai, Wei-Lun, Lee, Tzong-Hsi, Chen, Guei-Ying, Wang, Szu-Jen, Chang, Chun-Chao, Mo, Lein-Ray, Yang, Sheng-Shun, Wu, Wen-Chih, Huang, Chia-Sheng, Hsiung, Chou-Kwok, Kao, Chien-Neng, Tsai, Pei-Chien, Liu, Chen-Hua, Lee, Mei-Hsuan, Liu, Chun-Jen, Dai, Chia-Yen, Chuang, Wan-Long, Lin, Han-Chieh, Kao, Jia-Horng, and Yu, Ming-Lung

Published
2022
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41. Overall survival is comparable between percutaneous radiofrequency ablation and liver resection as first-line therapies for solitary 3–5 cm hepatocellular carcinoma.

Author

Chung, Shih-Da, Yong, Chee-Chien, Kee, Kwong-Ming, Lu, Sheng-Nan, Hu, Tsung-Hui, Wang, Jing-Houng, Hung, Chao-Hung, Chen, Chien-Hung, Liu, Yueh-Wei, Li, Wei-Feng, Wang, Chih-Chi, Yen, Yi-Hao, and Lin, Chih-Yun

Abstract

Purpose: Few studies have compared survival outcomes between liver resection (LR) and percutaneous radiofrequency ablation (RFA) for treating solitary 3–5 cm hepatocellular carcinoma (HCC). We aimed to clarify this issue. Methods: Patients with Child–Pugh class A liver disease and a solitary HCC of 3–5 cm without macrovascular invasion or extrahepatic metastasis who underwent LR or percutaneous RFA between 2011 and 2021 were enrolled in this retrospective study; 310 patients underwent LR and 114 patients underwent percutaneous RFA. Propensity score matching (PSM) was used to balance baseline variables, including age, sex, alpha-fetoprotein level, and Model for End-Stage Liver Disease score, between the two groups. Results: Before PSM, 5-year overall survival (OS) and recurrence-free survival (RFS) were significantly lower in the percutaneous RFA group than in the LR group (both p < 0.001). After PSM, 5-year OS was comparable between the two modalities (p = 0.367); however, 5-year RFS was significantly lower in the RFA group than in the LR group (p = 0.001). The two modalities did not differ in severe post-treatment complications (p = 1.000). Conclusions: Five-year OS did not differ between treatment modalities for patients with a solitary HCC of 3–5 cm; however, the LR group's 5-year RFS was superior. LR should be recommended as the first-line treatment for these patients. [ABSTRACT FROM AUTHOR]

Published
2025
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42. Impact of Sofosbuvir-Based Direct-Acting Antivirals on Renal Function in Chronic Hepatitis C Patients With Impaired Renal Function: A Large Cohort Study From the Nationwide HCV Registry Program (TACR)

Author

Huang, Chung-Feng, Tseng, Kuo-Chih, Cheng, Pin-Nan, Hung, Chao-Hung, Lo, Ching-Chu, Peng, Cheng-Yuan, Bair, Ming-Jong, Yeh, Ming-Lun, Chen, Chien-Hung, Lee, Pei-Lun, Lin, Chun-Yen, Kuo, Hsing-Tao, Chen, Chun-Ting, Yang, Chi-Chieh, Huang, Jee-Fu, Tai, Chi-Ming, Hu, Jui-Ting, Lin, Chih-Lang, Su, Wei-Wen, Tsai, Wei-Lun, Huang, Yi-Hsiang, Cheng, Chien-Yu, Lin, Chih-Lin, Wang, Chia-Chi, Yang, Sheng-Shun, Mo, Lein-Ray, Chen, Guei-Ying, Chang, Chun-Chao, Wang, Szu-Jen, Huang, Chia-Sheng, Hsieh, Tsai-Yuan, Lin, Chih-Wen, Lee, Tzong-Hsi, Chong, Lee-Won, Huang, Chien-Wei, Chang, Shiuh-Nan, Tsai, Ming-Chang, Hsu, Shih-Jer, Kao, Jia-Horng, Liu, Chun-Jen, Liu, Chen-Hua, Lin, Han-Chieh, Lee, Mei-Hsuan, Tsai, Pei-Chien, Dai, Chia-Yen, Chuang, Wan-Long, Chen, Chi-Yi, and Yu, Ming-Lung

Published
2022
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43. Probability of HBsAg loss after nucleo(s)tide analogue withdrawal depends on HBV genotype and viral antigen levels

Author

Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Höner zu Siederdissen, Christoph, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, and Maasoumy, Benjamin

Published
2022
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44. Progression Rates by Age, Sex, Treatment, and Disease Activity by AASLD and EASL Criteria: Data for Precision Medicine

Author

Park, Jiyoon, Le, An K., Tseng, Tai-Chung, Yeh, Ming-Lun, Jun, Dae Won, Trinh, Huy, Wong, Grace L.H., Chen, Chien-Hung, Peng, Cheng-Yuan, Kim, Sung Eun, Oh, Hyunwoo, Kwak, Min-Sun, Cheung, Ka Shing, Toyoda, Hidenori, Hsu, Yao-Chun, Jeong, Jae Yoon, Yoon, Eileen L., Ungtrakul, Teerapat, Zhang, Jian, Xie, Qing, Ahn, Sang Bong, Enomoto, Masaru, Shim, Jae-Jun, Cunningham, Chris, Jeong, Soung Won, Cho, Yong Kyun, Ogawa, Eiichi, Huang, Rui, Lee, Dong-Hyun, Takahashi, Hirokazu, Tsai, Pei-Chien, Huang, Chung-Feng, Dai, Chia-Yen, Tseng, Cheng-Hao, Yasuda, Satoshi, Kozuka, Ritsuzo, Li, Jiayi, Wong, Christopher, Wong, Clifford C., Zhao, Changqing, Hoang, Joseph, Eguchi, Yuichiro, Wu, Chao, Tanaka, Yasuhito, Gane, Ed, Tanwandee, Tawesak, Cheung, Ramsey, Yuen, Man-Fung, Lee, Hyo-Suk, Yu, Ming-Lung, Kao, Jia-Horng, Yang, Hwai-I, and Nguyen, Mindie H.

Published
2022
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46. Off-Therapy Response After Nucleos(t)ide Analogue Withdrawal in Patients With Chronic Hepatitis B: An International, Multicenter, Multiethnic Cohort (RETRACT-B Study)

Author

Hirode, Grishma, Choi, Hannah S.J., Chen, Chien-Hung, Su, Tung-Hung, Seto, Wai-Kay, Van Hees, Stijn, Papatheodoridi, Margarita, Lens, Sabela, Wong, Grace, Brakenhoff, Sylvia M., Chien, Rong-Nan, Feld, Jordan, Sonneveld, Milan J., Chan, Henry L.Y., Forns, Xavier, Papatheodoridis, George V., Vanwolleghem, Thomas, Yuen, Man-Fung, Hsu, Yao-Chun, Kao, Jia-Horng, Cornberg, Markus, Hansen, Bettina E., Jeng, Wen-Juei, and Janssen, Harry L.A.

Published
2022
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