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35. Supplementary Tables from Bioavailability of Sulforaphane from Two Broccoli Sprout Beverages: Results of a Short-term, Cross-over Clinical Trial in Qidong, China

Author

Egner, Patricia A., primary, Chen, Jian Guo, primary, Wang, Jin Bing, primary, Wu, Yan, primary, Sun, Yan, primary, Lu, Jian Hua, primary, Zhu, Jian, primary, Zhang, Yong Hui, primary, Chen, Yong Sheng, primary, Friesen, Marlin D., primary, Jacobson, Lisa P., primary, Muñoz, Alvaro, primary, Ng, Derek, primary, Qian, Geng Sun, primary, Zhu, Yuan Rong, primary, Chen, Tao Yang, primary, Botting, Nigel P., primary, Zhang, Qingzhi, primary, Fahey, Jed W., primary, Talalay, Paul, primary, Groopman, John D, primary, and Kensler, Thomas W., primary

Published
2023
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36. Data from Bioavailability of Sulforaphane from Two Broccoli Sprout Beverages: Results of a Short-term, Cross-over Clinical Trial in Qidong, China

Author

Egner, Patricia A., primary, Chen, Jian Guo, primary, Wang, Jin Bing, primary, Wu, Yan, primary, Sun, Yan, primary, Lu, Jian Hua, primary, Zhu, Jian, primary, Zhang, Yong Hui, primary, Chen, Yong Sheng, primary, Friesen, Marlin D., primary, Jacobson, Lisa P., primary, Muñoz, Alvaro, primary, Ng, Derek, primary, Qian, Geng Sun, primary, Zhu, Yuan Rong, primary, Chen, Tao Yang, primary, Botting, Nigel P., primary, Zhang, Qingzhi, primary, Fahey, Jed W., primary, Talalay, Paul, primary, Groopman, John D, primary, and Kensler, Thomas W., primary

Published
2023
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37. Supplementary Figure from Bioavailability of Sulforaphane from Two Broccoli Sprout Beverages: Results of a Short-term, Cross-over Clinical Trial in Qidong, China

Author

Egner, Patricia A., primary, Chen, Jian Guo, primary, Wang, Jin Bing, primary, Wu, Yan, primary, Sun, Yan, primary, Lu, Jian Hua, primary, Zhu, Jian, primary, Zhang, Yong Hui, primary, Chen, Yong Sheng, primary, Friesen, Marlin D., primary, Jacobson, Lisa P., primary, Muñoz, Alvaro, primary, Ng, Derek, primary, Qian, Geng Sun, primary, Zhu, Yuan Rong, primary, Chen, Tao Yang, primary, Botting, Nigel P., primary, Zhang, Qingzhi, primary, Fahey, Jed W., primary, Talalay, Paul, primary, Groopman, John D, primary, and Kensler, Thomas W., primary

Published
2023
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47. Long noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasis

Author

Chen, Hong-Sheng, primary, Wang, Ji, additional, Li, Hou-Hong, additional, Wang, Xiao, additional, Zhang, Shao-Qi, additional, Deng, Tan, additional, Li, Yu-Ke, additional, Zou, Ruo-Si, additional, Wang, Hua-Jie, additional, Zhu, Rui, additional, Xie, Wen-Long, additional, Zhao, Gang, additional, Wang, Fang, additional, and Chen, Jian-Guo, additional

Published
2022
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49. Additional file 1 of CD200 in dentate gyrus improves depressive-like behaviors of mice through enhancing hippocampal neurogenesis via alleviation of microglia hyperactivation

Author

Chen, Xi, Cui, Qian-Qian, Hu, Xiao-Hai, Ye, Jian, Liu, Zi-Cun, Mei, Yuan-Xi, Wang, Fang, Hu, Zhuang-Li, and Chen, Jian-Guo

Abstract

Additional file 1: Figure S1. mRNA expression of CD200 in different brain regions after exposure to CSDS. A Analysis of CD200 mRNA expression in the mPFC region of mice after CSDS. B Analysis of CD200 mRNA expression in the Hip region of mice after CSDS. C Analysis of CD200 mRNA expression in the DG region of mice after CSDS. D Analysis of CD200 mRNA expression in the CA1 region of mice after CSDS. E Analysis of CD200 mRNA expression in the CA3 region of mice after CSDS. Data are expressed as mean ± SEM. *P < 0.05; ***P < 0.001. Figure S2. Injection of CD200Fc into the lateral ventricle alleviates CSDS-induced depressive-like behavior. A Experimental timelines for CSDS procedure, CD200Fc administration and behavioral testing. B The social interaction ratio in the SIT of control and CSDS mice with exogenous CD200Fc injection. C, D The immobility time in the TSTand FSTof control and CSDS mice with exogenous CD200Fc injection. E The total distance in the OFT of control and CSDS mice with exogenous CD200Fc injection. Data are expressed as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001. Figure S3. Overexpression of CD200 in DG facilitates the expression of anti-inflammatory factors after CSDS. A Experimental timelines for CSDS procedure, AAV–CD200 stereotaxical injection and behavioral testing. B Analysis of mRNA levels of Arg-1, YM-1, IL-4, TNF-α, IL-6, and IL-1β after injection of AAV–CD200 virus to the DG region in susceptible mice. Data are expressed as mean ± SEM. *P < 0.05; **P < 0.01. Figure S4. CD200 increases the expression of BDNF in the DG brain region of susceptible mice. A Experimental timelines for CSDS procedure, CD200Fc administration and behavioral testing. B Representative immunostaining for BDNFin the DG of control and CSDS group after CD200Fc administration. Scale bars: 80 μm. C The fluorescence intensity of BDNF in the DG of control and CSDS group after CD200Fc administration. Data are expressed as mean ± SEM. *P < 0.05; ***P < 0.001. Figure S5. CD200Fc ameliorates adult hippocampal neurogenesis impairment in susceptible mice. A Experimental timelines for CSDS procedure, CD200Fc administration and behavioral testing. B Representative immunostaining for BrdU/DCX in the DG of control and CSDS group after CD200Fc administration. Scale bars: 40 μm. C, D Statistical graph for the number of BrdU+ and BrdU+ DCX+ cells in the DG of control and CSDS group after CD200Fc administration. Data are expressed as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001. Figure S6. Raw blot data for Fig. 1G, 3C and 4D. Table S1. Sequences of primers for qPCR. Table S2. Statistical analysis for each figure.

Published
2023
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