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1,375 results on '"Chen, Ling-Ling"'

8. Reconstruction of the Tea-Serving Automaton in the Ancient Japanese Book 'Karakuri Zui'

Author

Chai, Cheng-En, Chen, Ling-Ling, Chen, Yu-Hsun, Hsiao, Kuo-Hung, Lin, Jian-Liang, Yan, Hong-Sen, Ceccarelli, Marco, Series Editor, Agrawal, Sunil K., Advisory Editor, Corves, Burkhard, Advisory Editor, Glazunov, Victor, Advisory Editor, Hernández, Alfonso, Advisory Editor, Huang, Tian, Advisory Editor, Jauregui Correa, Juan Carlos, Advisory Editor, Takeda, Yukio, Advisory Editor, and Okada, Masafumi, editor

Published
2024
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17. Noncoding RNAs: biology and applications-a Keystone Symposia report.

Author

Cable, Jennifer, Heard, Edith, Hirose, Tetsuro, Prasanth, Kannanganattu, Chen, Ling-Ling, Henninger, Jonathan, Quinodoz, Sofia, Spector, David, Diermeier, Sarah, Porman, Allison, Kumar, Dhiraj, Feinberg, Mark, Shen, Xiaohua, Unfried, Juan, Johnson, Rory, Chen, Chun-Kan, Wilusz, Jeremy, Lempradl, Adelheid, McGeary, Sean, Wahba, Lamia, Pyle, Anna, Hargrove, Amanda, Simon, Matthew, Marcia, Marco, Przanowska, Róża, Chang, Howard, Jaffrey, Samie, Contreras, Lydia, Chen, Qi, Shi, Junchao, Mendell, Joshua, He, Lin, Song, Erwei, Rinn, John, Lalwani, Mukesh, Kalem, Murat, Chuong, Edward, Maquat, Lynne, and Liu, Xuhang

Subjects
Xist, circRNA, lncRNA, noncoding RNA, nuclear condensate, phase transition, piRNA, transcription, Animals, Congresses as Topic, Drug Delivery Systems, Epigenesis, Genetic, Gene Targeting, Humans, MicroRNAs, RNA, Long Noncoding, RNA, Small Interfering, RNA, Small Untranslated, RNA, Untranslated, Research Report, Signal Transduction
Abstract

The human transcriptome contains many types of noncoding RNAs, which rival the number of protein-coding species. From long noncoding RNAs (lncRNAs) that are over 200 nucleotides long to piwi-interacting RNAs (piRNAs) of only 20 nucleotides, noncoding RNAs play important roles in regulating transcription, epigenetic modifications, translation, and cell signaling. Roles for noncoding RNAs in disease mechanisms are also being uncovered, and several species have been identified as potential drug targets. On May 11-14, 2021, the Keystone eSymposium Noncoding RNAs: Biology and Applications brought together researchers working in RNA biology, structure, and technologies to accelerate both the understanding of RNA basic biology and the translation of those findings into clinical applications.

Published
2021

18. Long non-coding RNAs: definitions, functions, challenges and recommendations

Author

Mattick, John S., Amaral, Paulo P., Carninci, Piero, Carpenter, Susan, Chang, Howard Y., Chen, Ling-Ling, Chen, Runsheng, Dean, Caroline, Dinger, Marcel E., Fitzgerald, Katherine A., Gingeras, Thomas R., Guttman, Mitchell, Hirose, Tetsuro, Huarte, Maite, Johnson, Rory, Kanduri, Chandrasekhar, Kapranov, Philipp, Lawrence, Jeanne B., Lee, Jeannie T., Mendell, Joshua T., Mercer, Timothy R., Moore, Kathryn J., Nakagawa, Shinichi, Rinn, John L., Spector, David L., Ulitsky, Igor, Wan, Yue, Wilusz, Jeremy E., and Wu, Mian

Published
2023
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20. A New Space-Based Optical Surveillance System

Author

Sun, Yang, Chen, Ling-ling, Li, Xuan, Yang, Ye, Liu, Ling, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Sun, Jiande, editor, Wang, Yue, editor, Huo, Mengyao, editor, and Xu, Lexi, editor

Published
2023
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22. Two haplotype-resolved genome assemblies for AAB allotriploid bananas provide insights into banana subgenome asymmetric evolution and Fusarium wilt control

Author

Xie, Wen-Zhao, Zheng, Yu-Yu, He, Weidi, Bi, Fangcheng, Li, Yaoyao, Dou, Tongxin, Zhou, Run, Guo, Yi-Xiong, Deng, Guiming, Zhang, Wenhui, Yuan, Min-Hui, Sanz-Jimenez, Pablo, Zhu, Xi-Tong, Xu, Xin-Dong, Zhou, Zu-Wen, Zhou, Zhi-Wei, Feng, Jia-Wu, Liu, Siwen, Li, Chunyu, Yang, Qiaosong, Hu, Chunhua, Gao, Huijun, Dong, Tao, Dang, Jiangbo, Guo, Qigao, Cai, Wenguo, Zhang, Jianwei, Yi, Ganjun, Song, Jia-Ming, Sheng, Ou, and Chen, Ling-Ling

Published
2024
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23. High-quality genome assemblies for two Australimusa bananas (Musa spp.) and insights into regulatory mechanisms of superior fiber properties

Author

Zhou, Run, Wang, Shuo, Zhan, Ni, He, Weidi, Deng, Guiming, Dou, Tongxin, Zhu, Xi-Tong, Xie, Wen-Zhao, Zheng, Yu-Yu, Hu, Chunhua, Bi, Fangcheng, Gao, Huijun, Dong, Tao, Liu, Siwen, Li, Chunyu, Yang, Qiaosong, Wang, Lingqiang, Song, Jia-Ming, Dang, Jiangbo, Guo, Qigao, Yi, Ganjun, Chen, Ling-Ling, and Sheng, Ou

Published
2024
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26. A guide to naming eukaryotic circular RNAs

Author

Chen, Ling-Ling, Bindereif, Albrecht, Bozzoni, Irene, Chang, Howard Y., Matera, A. Gregory, Gorospe, Myriam, Hansen, Thomas B., Kjems, Jørgen, Ma, Xu-Kai, Pek, Jun Wei, Rajewsky, Nikolaus, Salzman, Julia, Wilusz, Jeremy E., Yang, Li, and Zhao, Fangqing

Published
2023
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27. A multi-omics integrative network map of maize

Author

Han, Linqian, Zhong, Wanshun, Qian, Jia, Jin, Minliang, Tian, Peng, Zhu, Wanchao, Zhang, Hongwei, Sun, Yonghao, Feng, Jia-Wu, Liu, Xiangguo, Chen, Guo, Farid, Babar, Li, Ruonan, Xiong, Zimo, Tian, Zhihui, Li, Juan, Luo, Zi, Du, Dengxiang, Chen, Sijia, Jin, Qixiao, Li, Jiaxin, Li, Zhao, Liang, Yan, Jin, Xiaomeng, Peng, Yong, Zheng, Chang, Ye, Xinnan, Yin, Yuejia, Chen, Hong, Li, Weifu, Chen, Ling-Ling, Li, Qing, Yan, Jianbing, Yang, Fang, and Li, Lin

Published
2023
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37. Nuclear bodies: concentrating at an aqueous site.

Author

Chen, Ling-Ling, Larschan, Erica, Matera, A. Gregory, Strom, Amy, and Pederson, Thoru

Subjects
*PHASE separation, *NON-coding RNA, *CAREER development, *GENE expression, *MOLECULAR dynamics
Abstract

The second FASEB conference on Nuclear Bodies: Hubs of Genome Activity was held June 2–7, 2024, at Niagara Falls, NY. The central theme was how these protein and RNA–protein complexes that are situated in the nucleus outside the genome support and regulate gene expression. Topics included their relevance to disease, especially cancer, their molecular dynamics, and their phase separation transition properties. The meeting included numerous trainees as speakers and session chairs, hosted a memorable Keynote talk on diversity, and a vibrant career development session. [ABSTRACT FROM AUTHOR]

Published
2024
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38. Characterization of Major Cell-Wall-Degrading Enzymes Secreted by Diaporthe spp. Isolate Z1-1N Causing Postharvest Fruit Rot in Kiwifruit in China.

Author

Ling, Li-Zhen, Chen, Ling-Ling, Ma, Jia-Yu, Li, Chao-Yue, Zhang, Dong-Ru, Hu, Xiao-Di, and Zhang, Shu-Dong

Subjects
*CARBOXYMETHYLCELLULOSE, *KIWIFRUIT industry, *FRUIT rots, *PECTIC enzymes, *POLYGALACTURONASE, *KIWIFRUIT
Abstract

Simple Summary: To better understand the pathogenicity of Diaporthe isolate Z1-1N, one of the major causal agents of soft rot disease in kiwifruit, we detected the activities of six CWDEs, including polygalacturonase (PG), polymethylgalacturonase (PMG), polygalacturonic acid transeliminase (PGTE), pectin methyltranseliminase (PMTE), endoglucanase (Cx), and β-glucosidase (β-glu), in vitro and in vivo. Our results indicated that Diaporthe Z1-1N can secrete four pectinases and two cellulases, which exhibited varying degrees of pathogenicity. Among the four pectinases, PG and PMG consistently demonstrated high activities in both liquid culture media and infected tissues. In contrast, only low activities of PGTE and PMTE were observed during infection, with no activity detected in the liquid cultures. Additionally, two cellulases of β-glucosidase and endoglucanase exhibited differing levels of activities, particularly showing a significant increase during infection by Diaporthe Z1-1N. Our results indicated that the activities of PG, PMG, β-glu, and Cx peaked at three or four days after infection with Diaporthe Z1-1N on kiwifruit. Furthermore, the levels of PG and PMG were higher than those of Cx and β-glu throughout the incubation periods. In conclusion, Diaporthe Z1-1N can secrete various types of pectinases and cellulases, with cellulases (Cx and β-glu) and pectinases (PMG and PG) playing crucial roles during infection. Pathogen-induced fruit decay is a significant threat to the kiwifruit industry, leading to considerable economic losses annually. The cell-wall-degrading enzymes (CWDEs) secreted by these pathogens are crucial for penetrating the cell wall and accessing nutrients. Among them, Diaporthe species are recognized as major causal agents of soft rot in kiwifruit, yet their pathogenic mechanisms are not well understood. In this study, we explored the production of various CWDEs secreted by Diaporthe Z1-1N, including polygalacturonase (PG), polymethylgalacturonase (PMG), polygalacturonic acid transeliminase (PGTE), pectin methyltranseliminase (PMTE), endoglucanase (Cx), and β-glucosidase (β-glu), both in liquid cultures and within infected kiwifruit tissues. Our findings revealed significant activities of two pectinases (PG and PMG) and cellulases (Cx and β-glu) in the infected tissues. In contrast, very low levels of PMTE and PGTE activities were observed under the same conditions. When orange pectin served as the carbon source, PG and PMG showed notable activities, while PMTE and PGTE remained inactive. Moreover, the activities of Cx and β-glu significantly decreased by more than 63 times in the liquid medium with carboxymethyl cellulose (CMC) as the carbon source compared to their levels in infected kiwifruit. A further analysis indicated that the necrotic lesions produced by pectinase extracts were larger than those produced by cellulase extracts. Notably, four enzymes—PG, PMG, Cx, and β-glu—exhibited high activities on the third or fourth day post-infection with Diaporthe Z1-1N. These results suggest that Diaporthe Z1-1N secretes a range of CWDEs that contribute to kiwifruit decay by enhancing the activities of PG, PMG, Cx, and β-glu. This study sheds light on the pathogenicity of Diaporthe in kiwifruit and highlights the importance of these enzymes in the decay process. [ABSTRACT FROM AUTHOR]

Published
2024
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