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426 results on '"Chen, Miao-Fen"'

7. A meta‐analysis comparing efficacy and safety between proton beam therapy versus carbon ion radiotherapy.

Author

Jang, Jeong Yun, Kim, Kangpyo, Chen, Miao‐Fen, Akimoto, Tetsuo, Wang, Michael Lian Chek, Kim, Min‐Ji, Kim, Kyunga, Lee, Tae Hoon, Yoo, Gyu Sang, and Park, Hee Chul

Subjects
PROTON therapy, RADIOTHERAPY, PROGRESSION-free survival, TREATMENT effectiveness, CARBON
Abstract

Background: This study aimed to compare the outcomes of proton beam therapy (PBT) and carbon ion radiotherapy (CIRT) by a systematic review and meta‐analysis of the existing clinical evidence. Methods: A systematic literature search was performed to identify studies comparing the clinical outcomes of PBT and CIRT. The included studies were required to report oncological outcomes (local control [LC], progression‐free survival [PFS], or overall survival [OS]) or adverse events. Results: Eighteen articles comprising 1857 patients (947 treated with PBT and 910 treated with CIRT) were included in the analysis. The pooled analysis conducted for the overall population yielded average hazard ratios of 0.690 (95% confidence interval (CI), 0.493–0.967, p = 0.031) for LC, 0.952 (95% CI, 0.604–1.500, p = 0.590) for PFS, and 1.183 (0.872–1.607, p = 0.281) for OS with reference to CIRT. The subgroup analyses included patients treated in the head and neck, areas other than the head and neck, and patients with chordomas and chondrosarcomas. These analyses revealed no significant differences in most outcomes, except for LC in the subgroup of patients treated in areas other than the head and neck. Adverse event rates were comparable in both groups, with an odds ratio (OR) of 1.097 (95% CI, 0.744–1.616, p = 0.641). Meta‐regression analysis for possible heterogeneity did not demonstrate a significant association between treatment outcomes and the ratio of biologically effective doses between modalities. Conclusion: This study highlighted the comparability of PBT and CIRT in terms of oncological outcomes and adverse events. [ABSTRACT FROM AUTHOR]

Published
2024
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8. A multicenter retrospective analysis of patients with salivary gland carcinoma treated with postoperative radiotherapy alone or chemoradiotherapy

Author

Cheng-En Hsieh, Rodney, primary, Chou, Yung-Chih, additional, Hung, Chia-Yen, additional, Lee, Li-Yu, additional, Prasad Venkatesulu, Bhanu, additional, Huang, Shiang-Fu, additional, Liao, Chun-Ta, additional, Cheng, Nai-Ming, additional, Wang, Hung-Ming, additional, Wu, Chiao-En, additional, Kang, Chung-Jan, additional, Chen, Miao-Fen, additional, Cheng, Yu-Fan, additional, Yeh, Kun-Yun, additional, Wang, Cheng-Hsu, additional, Chou, Wen-Chi, additional, and Lin, Chien-Yu, additional

Published
2023
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26. Adjuvant Chemoradiotherapy Associated with Improved Overall Survival in Resected Esophageal Squamous Cell Carcinoma after Neoadjuvant Chemoradiotherapy in Intensity-Modulated Radiotherapy Era

Author

Yap, Wing-Keen, primary, Shih, Ming-Chieh, additional, Chang, Yu-Chen, additional, Lin, Chia-Hsin, additional, Huang, Shih-Ming, additional, Tsai, Tsung-You, additional, Chang, Ching-Fu, additional, Hsu, Chih-Chung, additional, Tseng, Chen-Kan, additional, Chen, Miao-Fen, additional, Tsan, Din-Li, additional, Liau, Chi-Ting, additional, Hou, Ming-Mo, additional, Chao, Yin-Kai, additional, Chiu, Chien-Hung, additional, and Hung, Tsung-Min, additional

Published
2022
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49. Lung cancer outcome in the setting of chronic kidney disease: Does the glomerular filtration estimation formula matter?

Author

Lu, Ming‐Shian, Lu, Hung‐I, Chen, Tzu‐Ping, Chen, Miao‐Fen, Lin, Chien‐Chao, Tseng, Yuan‐Hsi, and Tsai, Ying‐Huang

Subjects
Male, Lung Neoplasms, Adenocarcinoma, urologic and male genital diseases, survival, lcsh:RC254-282, Risk Factors, Carcinoma, Non-Small-Cell Lung, Chronic kidney disease, Humans, Renal Insufficiency, Chronic, Aged, Retrospective Studies, Original Articles, Prognosis, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Small Cell Lung Carcinoma, female genital diseases and pregnancy complications, Survival Rate, lung cancer, Carcinoma, Squamous Cell, outcome, Original Article, Female, Follow-Up Studies, Glomerular Filtration Rate
Abstract

Background The survival outcomes of lung cancer patients with coexisting chronic kidney disease (CKD) reported in the literature have been conflicting. We evaluate whether the survival of lung cancer patients with and without CKD differ significantly using two different formulas. Methods A retrospective, multicenter, propensity‐matched study of lung cancer patients with and without CKD was conducted. CKD was defined as an estimated glomerular filtration rate (eGFR) < 60 mL/minute. Kaplan–Meier survival analysis was used to determine survival differences between CKD and non‐CKD patients using the Cockcroft–Gault formula (CKD–CG) compared to the Chronic Kidney Disease Epidemiology Collaboration Formula (CKD‐EPI). Results Baseline clinical characteristics did not differ statistically significantly between the groups. The CKD‐CG formula demonstrated median survival of 10.61 months (95% confidence interval [CI] 9.33–11.89) for the non‐CKD group compared to 10.58 months (95% CI 9.03–12.13) for the CKD group (P = 0.76). The CKD‐EPI formula demonstrated median survival of 9.10 months (95% CI 8.01–10.20) for the non‐CKD group compared to 7.59 months (95% CI 6.50–8.68) for the CKD group (P = 0.19). Cox regression analysis using both models revealed that CKD is not an independent risk factor for mortality in lung cancer patients. Although the CKD‐EPI formula revealed an increased risk of mortality and the CKD‐CG formula revealed decreased survival, these results were not statistically significant. Conclusion Lung cancer survival did not differ significantly between CKD and non‐CKD patients using either formula.

Published
2019

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