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5. Renal function is associated with 1-month and 1-year mortality in patients with ischemic stroke

Author

Liu, Chung-Hsiang, Tsai, Chon-Haw, Huang, Wei-Shih, Lu, Chung-Ta, Tsai, Tzung-Chang, Tseng, Chun-Hung, Lin, Kang-Hsu, Shyu, Woei-Cherng, Yang, Yu-Wan, Liu, Yen-Liang, Cho, Der-Yang, Chen, Chun-Chung, Jeng, Jiann-Shing, Tang, Sung-Chun, Tsai, Li-Kai, Yeh, Shin-Joe, Chen, Chih-Hao, Tsai, Hsin-Hsi, Li, Jie-Yuan, Chen, Han-Jung, Lu, Kan, Hsu, Shih-Pin, Kuo, Hung-Chang, Tsou, Jung-Chi, Wang, Yan-Tang, Tai, Yi-Cheng, Hsieh, Meng-Tsang, Liliang, Po-Chao, Liang, Cheng-Loong, Wang, Hao-Kuang, Tsai, Yu-Tun, Wang, Kuo-Wei, Chen, Jui-Sheng, Chen, Po-Yuan, Wang, Yi-Ching, Chen, Chih-Hung, Sung, Pi-Shan, Hsieh, Han-Chieh, Su, Hui-Chen, Chiu, Hou-Chang, Lien, Li-Ming, Chen, Wei-Hung, Bai, Chyi-Huey, Huang, Tzu-Hsuan, Lau, Chi-Ieong, Wu, Ya-Ying, Yeh, Hsu-Ling, Chang, Anna, Lin, Ching-Huang, Yen, Cheng-Chang, Lin, Ruey-Tay, Chen, Chun-Hung, Khor, Gim-Thean, Chao, A-Ching, Lin, Hsiu-Fen, Huang, Poyin, Lin, Huey-Juan, Ke, Der-Shin, Chang, Chia-Yu, Yeh, Poh-Shiow, Lin, Kao-Chang, Cheng, Tain-Junn, Chou, Chih-Ho, Yang, Chun-Ming, Shen, Hsiu-Chu, Chen, An-Chih, Tsai, Shih-Jei, Lu, Tsong-Ming, Kung, Sheng-Ling, Lee, Mei-Ju, Chou, Hsi-Hsien, Chang, Wei-Lun, Chiu, Pai-Yi, Hsu, Min-Hsien, Chan, Po-Chi, Pan, Chau-Hsiung, Shoung, Hai-Ming, Lo, Yi-Chen, Wang, Fu-Hwa, Chang, Wei-Chieh, Lai, Ta-Chang, Yin, Jiu-Haw, Wang, Chung-Jen, Wang, Kai-Chen, Chen, Li-Mei, Denq, Jong-Chyou, Sun, Yu, Lu, Chien-Jung, Lin, Cheng-Huai, Huang, Chieh-Cheng, Liu, Chang-Hsiu, Chan, Hoi-Fong, Lee, Siu-Pak, Sun, Ming-Hui, Ke, Li-Ying, Chen, Po-Lin, Lee, Yu-Shan, Sung, Sheng-Feng, Ong, Cheung-Ter, Wu, Chi-Shun, Hsu, Yung-Chu, Su, Yu-Hsiang, Hung, Ling-Chien, Lee, Jiunn-Tay, Lin, Jiann-Chyun, Hsu, Yaw-Don, Peng, Giia-Sheun, Hsu, Chang-Hung, Lin, Chun-Chieh, Yen, Che-Hung, Cheng, Chun-An, Sung, Yueh-Feng, Chen, Yuan-Liang, Lien, Ming-Tung, Chou, Chung-Hsing, Liu, Chia-Chen, Yang, Fu-Chi, Wu, Yi-Chung, Tso, An-Chen, Lai, Yu- Hua, Chiang, Chun-I., Tsai, Chia-Kuang, Liu, Meng-Ta, Lin, Ying-Che, Hsu, Yu-Chuan, Chiang, Tsuey-Ru, Huang, Pai-Hao, Liao, Pin-Wen, Lee, Mei-Ching, Chen, Jen-Tse, Lie, Sian-King, Sun, Mu-Chien, Hsiao, Pi-Ju, Chen, Wei-Liang, Chen, Ta-Cheng, Chang, Chen-Shu, Lai, Chien-Hsu, Chuang, Chieh-Sen, Chen, Yen-Yu, Lin, Shinn-Kuang, Su, Yu-Chin, Shiao, Jen-Lun, Yang, Fu-Yi, Liu, Chih-Yang, Chiang, Han-Lin, Chen, Guei-Chiuan, Hsu, Po-Jen, Chang, Chun-Yuan, Lin, I.-sheng, Chien, Chung-Hsien, Chang, Yang-Chuang, Chen, Ping-Kun, Hsiao, Yu-Jen, Fang, Chen-Wen, Chen, Yu-Wei, Lee, Kuo-Ying, Lin, Yun-Yu, Li, Chen-Hua, Tsai, Hui-Fen, Hsieh, Chuan-Fa, Yang, Chih-Dong, Liaw, Shiumn-Jen, Liao, How-Chin, Yeh, Shoou-Jeng, Wu, Ling-Li, Hsieh, Liang-Po, Lee, Yong-Hui, Chen, Chung-Wen, Hsu, Chih-Shan, Jhih, Ye-Jian, Zhuang, Hao-Yu, Pan, Yan-Hong, Shih, Shin-An, Chen, Chin-I., Sung, Jia-Ying, Weng, Hsing-Yu, Teng, Hao-Wen, Lee, Jing-Er, Huang, Chih-Shan, Chao, Shu-Ping, Yuan, Rey-Yue, Sheu, Jau-Jiuan, Yu, Jia-Ming, Ho, Chun-Sum, Lin, Ting-Chun, Yu, Shih-Chieh, Chen, Jiunn-Rong, Tsai, Song-Yen, Wei, Cheng-Yu, Hung, Chao-Hsien, Lee, Chia Fang, Yang, Sheng-Kung, Chen, Chih-Lin, Lin, Wei, Tseng, Hung-Pin, Liu, Chin-Hsiung, Lin, Chun-Liang, Lin, Hung-Chih, Chen, Pi-Tzu, Hu, Chaur-Jong, Chan, Lung, Chi, Nai-Fang, Chern, Chang-Ming, Lin, Chun-Jen, Wang, Shuu-Jiun, Hsu, Li-Chi, Wong, Wen-Jang, Lee, I-Hui, Yen, Der-Jen, Tsai, Ching-Piao, Kwan, Shang-Yeong, Soong, Bing-Wen, Chen, Shih-Pin, Liao, Kwong-Kum, Lin, Kung-Ping, Chen, Chien, Shan, Din-E., Fuh, Jong-Ling, Wang, Pei-Ning, Lee, Yi-Chung, Yu, Yu-Hsiang, Huang, Hui-Chi, Tsai, Jui-Yao, Wu, Ming-Hsiu, Chiang, Szu-Yi, Wang, Chiung-Yao, Hsu, Ming-Chin, Chen, Chien-Chung, Yeh, Po-Yen, Tsai, Yu-Tai, Wang, Ko-Yi, Chen, Tsang-Shan, Hsieh, Cheng-Yang, Chen, Wei-Fen, Yip, Ping-Keung, Wang, Vinchi, Wang, Kaw-Chen, Tsai, Chung-Fen, Chen, Chao-Ching, Liu, Yi-Chien, Chen, Shao-Yuan, Zhao, Zi-Hao, Wei, Zhi-Peng, Wu, Shey-Lin, Liu, Ching-Kuan, Lin, Ryh-Huei, Chu, Ching-Hua, Yan, Sui-Hing, Lin, Yi-Chun, Chen, Pei-Yun, Hsiao, Sheng-Huang, Yip, Bak-Sau, Tsai, Pei-Chun, Chou, Ping-Chen, Kuo, Tsam-Ming, Lee, Yi-Chen, Chiu, Yi-Pin, Tsai, Kun-Chang, Liao, Yi-Sheng, Tsai, Ming-Jun, Kao, Hsin-Yi, Wang, I-Kuan, Yen, Tzung-Hai, Tsai, I-Ju, Sung, Fung-Chang, and Hsu, Chung Y.

Published
2018
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8. Cholesterol Levels Are Associated with 30-day Mortality from Ischemic Stroke in Dialysis Patients

Author

Liu, Chung-Hsiang, Tsai, Chon-Haw, Huang, Wei-Shih, Lu, Chung-Ta, Tsai, Tzung-Chang, Tseng, Chun-Hung, Lin, Kang-Hsu, Shyn, Woei-Cherng, Yang, Yu-Wan, Liu, Yen-Liang, Cho, Der-Yang, Chen, Chun-Chung, Jeng, Jiann-Shing, Tang, Sung-Chun, Tsai, Li-Kai, Yeh, Shin-Joe, Hsu, Shih-Pin, Chen, Han-Jung, Chang, Cheng-Sen, Kuo, Hung-Chang, Lee, Lian-Hui, Tsui, Huan-Wen, Tsou, Jung-Chi, Wang, Yan-Tang, Tai, Yi-Cheng, Tsai, Kun-Chang, Chen, Yen-Wen, Lu, Kan, Liliang, Po-Chao, Tsai, Yu-Tun, Liang, Cheng-Loong, Wang, Kuo-Wei, Wang, Hao-Kuang, Chen, Jui-Sheng, Chen, Po-Yuan, Chye, Cien-Leong, Tzeng, Wei-Jie, Wu, Pei-Hua, Chen, Chih-Hung, Sung, Pi-Shan, Hsieh, Han-Chieh, Su, Hui-Chen, Chiu, Hou-Chang, Lien, Li-Ming, Chen, Wei-Hung, Bai, Chyi-Huey, Huang, Tzu-Hsuan, Lau, Chi-Ieong, Wu, Ya-Ying, Yeh, Hsu-Ling, Chang, Anna, Lin, Ching-Huang, Yen, Cheng-Chang, Lin, Ruey-Tay, Chen, Chun-Hung, Khor, Gim-Thean, Chao, A-Ching, Lin, Hsiu-Fen, Huang, Poyin, Lin, Huey-Juan, Ke, Der-Shin, Chang, Chia-Yu, Yeh, Poh-Shiow, Lin, Kao-Chang, Cheng, Tain-Junn, Chou, Chih-Ho, Yang, Chun-Ming, Shen, Hsiu-Chu, Chen, An-Chih, Tsai, Shih-Jei, Lu, Tsong-Ming, Kung, Sheng-Ling, Lee, Mei-Ju, Chou, Hsi-Hsien, Chi, Hsin-Yi, Pan, Chou-Hsiung, Chan, Po-Chi, Hsu, Min-Hsien, Chang, Wei-Lun, Huang, Zhi-Zang, Shoung, Hai-Ming, Lo, Yi-Chen, Wang, Fu-Hwa, Lai, Ta-Chang, Yin, Jiu-Haw, Wang, Chung-Jen, Wang, Kai-Chen, Chen, Li-Mei, Denq, Jong-Chyou, Sun, Yu, Lu, Chien-Jung, Lin, Cheng-Huai, Huang, Chieh-Cheng, Liu, Chang-Hsiu, Chan, Hoi-Fong, Lee, Siu-Pak, Sun, Ming-Hui, Ke, Li-Ying, Chen, Po-Lin, Lee, Yu-Shan, Sung, Sheng-Feng, Ong, Cheung-Ter, Wu, Chi-Shun, Hsu, Yung-Chu, Su, Yu-Hsiang, Hung, Ling-Chien, Lee, Jiunn-Tay, Lin, Jiann-Chyun, Hsu, Yaw-Don, Peng, Giia-Sheun, Hsu, Chang-Hung, Lin, Chun-Chieh, Yen, Che-Hung, Cheng, Chun-An, Sung, Yueh-Feng, Chen, Yuan-Liang, Lien, Ming-Tung, Chou, Chung-Hsing, Liu, Chia-Chen, Yang, Fu-Chi, Wu, Yi-Chung, Tso, An-Chen, Lai, Yu-Hua, Chiang, Chun-I, Tsai, Chia-Kuang, Liu, Meng-Ta, Lin, Ying-Che, Hsu, Yu-Chuan, Chiang, Tsuey-Ru, Lee, Mei-Ching, Huang, Pai-Hao, Lie, Sian-King, Liao, Pin-Wen, Chen, Jen-Tse, Sun, Mu-Chien, Lai, Tien-Pao, Chen, Wei-Liang, Chen, Yen-Chun, Chen, Ta-Cheng, Wang, Wen-Fu, Lee, Kwo-Whei, Chang, Chen-Shu, Lai, Chien-Hsu, Shih, Siao-Ya, Chuang, Chieh-Sen, Chen, Yen-Yu, Chen, Chien-Min, Lin, Shinn-Kuang, Su, Yu-Chin, Hsiao, Cheng-Lun, Yang, Fu-Yi, Liu, Chih-Yang, Chiang, Han-Lin, Chang, Chun-Yuan, Lin, I-sheng, Chien, Chung-Hsien, Chang, Yang-Chuang, Chen, Ping-Kun, Chiu, Pai-Yi, Hsiao, Yu-Jen, Fang, Chen-Wen, Chen, Yu-Wei, Lee, Kuo-Ying, Lin, Yun-Yu, Li, Chen-Hua, Tsai, Hui-Fen, Hsieh, Chuan-Fa, Yang, Chih-Dong, Liaw, Shiumn-Jen, Liao, How-Chin, Yeh, Shoou-Jeng, Wu, Ling-Li, Hsieh, Liang-Po, Lee, Yong-Hui, Chen, Chung-Wen, Hsu, Chih-Shan, Jhih, Ye-Jian, Zhuang, Hao-Yu, Pan, Yan-Hong, Shih, Shin-An, Chen, Chin-I, Sung, Jia-Ying, Weng, Hsing-Yu, Teng, Hao-Wen, Lee, Jing-Er, Huang, Chih-Shan, Chao, Shu-Ping, Yuan, Rey-Yue, Sheu, Jau- Jiuan, Yu, Jia-Ming, Ho, Chun-Sum, Lin, Ting-Chun, Yu, Shih-Chieh, Chen, Jiunn-Rong, Tsai, Song-Yen, Wei, Cheng-Yu, Yang, Chao-Nan, Hung, Chao-Hsien, Shih, Ian, Tseng, Hung-Pin, Liu, Chin-Hsiung, Lin, Chun-Liang, Lin, Hung-Chih, Chen, Pi-Tzu, Hu, Chaur-Jong, Chi, Nai-Fang, Chan, Lung, Chern, Chang-Ming, Lin, Chun-Jen, Wang, Shuu-Jiun, Hsu, Li-Chi, Wong, Wen-Jang, Lee, I-Hui, Yen, Der-Jen, Tsai, Ching-Piao, Kwan, Shang-Yeong, Soong, Bing-Wen, Chen, Shih-Pin, Liao, Kwong-Kum, Lin, Kung-Ping, Chen, Chien, Shan, Din-E, Fuh, Jong-Ling, Wang, Pei-Ning, Lee, Yi-Chung, Yu, Yu-Hsiang, Huang, Hui-Chi, Tsai, Jui-Yao, Wu, Ming-Hsiu, Chen, Shi-Cheng, Chiang, Szu-Yi, Wang, Chiung-Yao, Hsu, Ming-Chin, Chen, Chien-Chung, Yeh, Po-Yen, Tsai, Yu-Tai, Wang, Ko-Yi, Chen, Tsang-Shan, Yip, Ping-Keung, Wang, Vinchi, Wang, Kaw-Chen, Tsai, Chung-Fen, Chen, Chao-Ching, Chen, Chih-Hao, Liu, Yi-Chien, Chen, Shao-Yuan, Zhao, Zi-Hao, Wei, Zhi-Peng, Wu, Shey-Lin, Liu, Ching-Kuan, Lin, Ryh-Huei, Chu, Ching-Hua, Yan, Sui-Hing, Lin, Yi-Chun, Chen, Pei-Yun, Hsiao, Sheng-Huang, Yip, Bak-Sau, Tsai, Pei-Chun, Chou, Ping-Chen, Kuo, Tsam-Ming, Lee, Yi-Chen, Chiu, Yi-Pin, Liao, Yi-Sheng, Tsai, Ming-Jun, Kao, Hsin-Yi, Wang, I.-Kuan, Yen, Tzung-Hai, Muo, Chih-Hsin, Ma, Henry, Wen, Chi-Pang, Sung, Fung-Chang, and Hsu, Chung Y.

Published
2017
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13. Prevalence and Effect of Cerebral Small Vessel Disease in Stroke Patients With Aspirin Treatment Failure–A Hospital-Based Stroke Secondary Prevention Registry

Author

Chou, Ping-Song, primary, Sung, Pi-Shan, additional, Liu, Chi-Hung, additional, Sung, Yueh-Feng, additional, Tzeng, Ray-Chang, additional, Yang, Chun-Pai, additional, Lien, Chi-Hsun, additional, Po, Helen L., additional, Ho, Shang-Chang, additional, Tsai, Yi-Te, additional, Chen, Tsang-Shan, additional, Wu, Shey-Lin, additional, Hu, Han-Hwa, additional, and Chao, A-Ching, additional

Published
2021
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19. Predictive value of ankle–brachial index for long-term events of ischemic stroke in hemodialysis patients.

Author

Lee, Kai-Ni, Chou, Li-Ping, Liu, Chi-Chu, Chen, Tsang-Shan, Lui, Eric Kim-Tai, Chou, Chih-Ho, and Chen, Chien-An

Abstract

Objectives: The ankle–brachial index is a noninvasive modality to evaluate atherosclerosis and is a predictive role for future cardiovascular events and mortality. However, few studies have evaluated its relation to long-term future ischemic stroke in hemodialysis patients. Therefore, we examined the relationship between ankle–brachial index and ischemic stroke events among hemodialysis patients in a seven-year follow-up. Methods: A total of 84 patients were enrolled. Ankle–brachial index was assessed in January 2009. Primary outcomes included ischemic stroke. An ankle–brachial index < 0.9 was considered abnormal and 1.4 ≥ ankle–brachial index ≥ 0.9 to be normal ankle–brachial index. Results: Mean values for ankle–brachial index were 0.98 ± 0.21at study entrance. In addition, 28 patients encountered ischemic stroke in the seven-year follow-up. In univariate Cox regression analysis, old age (hazard ratio (HR): 1.065, 95% confidence interval (CI): 1.030–1.102, p < 0.001), low seven-year averaged serum phosphate levels (HR: 0.473, 95% CI: 0.306–0.730, p = 0.001), and abnormal ankle–brachial index (HR: 0.035, 95% CI: 0.009–0.145, p < 0.001) were risk factors for ischemic stroke. In multivariate Cox regression analysis for significant variables in univariate analysis, abnormal ankle–brachial index (HR: 0.058, 95% CI: 0.012–0.279, p < 0.001) and low seven-year averaged serum phosphate levels (HR: 0.625, 95% CI: 0.404–0.968, p = 0.035) remained the risk factors for ischemic stroke. The risk of ischemic stroke was 3.783-fold in patients with abnormal ankle–brachial index compared with patients with normal ankle–brachial index (HR: 3.783, 95% CI: 1.731–8.269, p = 0.001). Conclusions: These findings suggest that ankle–brachial index is an impressive predictor of future ischemic stroke among hemodialysis patients. [ABSTRACT FROM AUTHOR]

Published
2021
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21. Renal function is associated with 1-month and 1-year mortality in patients with ischemic stroke

Author

Wang, I-Kuan, primary, Liu, Chung-Hsiang, additional, Yen, Tzung-Hai, additional, Jeng, Jiann-Shing, additional, Sung, Sheng-Feng, additional, Huang, Pai-Hao, additional, Li, Jie-Yuan, additional, Sun, Yu, additional, Wei, Cheng-Yu, additional, Lien, Li-Ming, additional, Tsai, I-Ju, additional, Sung, Fung-Chang, additional, Hsu, Chung Y., additional, Tsai, Chon-Haw, additional, Huang, Wei-Shih, additional, Lu, Chung-Ta, additional, Tsai, Tzung-Chang, additional, Tseng, Chun-Hung, additional, Lin, Kang-Hsu, additional, Shyu, Woei-Cherng, additional, Yang, Yu-Wan, additional, Liu, Yen-Liang, additional, Cho, Der-Yang, additional, Chen, Chun-Chung, additional, Tang, Sung-Chun, additional, Tsai, Li-Kai, additional, Yeh, Shin-Joe, additional, Chen, Chih-Hao, additional, Tsai, Hsin-Hsi, additional, Chen, Han-Jung, additional, Lu, Kan, additional, Hsu, Shih-Pin, additional, Kuo, Hung-Chang, additional, Tsou, Jung-Chi, additional, Wang, Yan-Tang, additional, Tai, Yi-Cheng, additional, Hsieh, Meng-Tsang, additional, Liliang, Po-Chao, additional, Liang, Cheng-Loong, additional, Wang, Hao-Kuang, additional, Tsai, Yu-Tun, additional, Wang, Kuo-Wei, additional, Chen, Jui-Sheng, additional, Chen, Po-Yuan, additional, Wang, Yi-Ching, additional, Chen, Chih-Hung, additional, Sung, Pi-Shan, additional, Hsieh, Han-Chieh, additional, Su, Hui-Chen, additional, Chiu, Hou-Chang, additional, Chen, Wei-Hung, additional, Bai, Chyi-Huey, additional, Huang, Tzu-Hsuan, additional, Lau, Chi-Ieong, additional, Wu, Ya-Ying, additional, Yeh, Hsu-Ling, additional, Chang, Anna, additional, Lin, Ching-Huang, additional, Yen, Cheng-Chang, additional, Lin, Ruey-Tay, additional, Chen, Chun-Hung, additional, Khor, Gim-Thean, additional, Chao, A-Ching, additional, Lin, Hsiu-Fen, additional, Huang, Poyin, additional, Lin, Huey-Juan, additional, Ke, Der-Shin, additional, Chang, Chia-Yu, additional, Yeh, Poh-Shiow, additional, Lin, Kao-Chang, additional, Cheng, Tain-Junn, additional, Chou, Chih-Ho, additional, Yang, Chun-Ming, additional, Shen, Hsiu-Chu, additional, Chen, An-Chih, additional, Tsai, Shih-Jei, additional, Lu, Tsong-Ming, additional, Kung, Sheng-Ling, additional, Lee, Mei-Ju, additional, Chou, Hsi-Hsien, additional, Chang, Wei-Lun, additional, Chiu, Pai-Yi, additional, Hsu, Min-Hsien, additional, Chan, Po-Chi, additional, Pan, Chau-Hsiung, additional, Shoung, Hai-Ming, additional, Lo, Yi-Chen, additional, Wang, Fu-Hwa, additional, Chang, Wei-Chieh, additional, Lai, Ta-Chang, additional, Yin, Jiu-Haw, additional, Wang, Chung-Jen, additional, Wang, Kai-Chen, additional, Chen, Li-Mei, additional, Denq, Jong-Chyou, additional, Lu, Chien-Jung, additional, Lin, Cheng-Huai, additional, Huang, Chieh-Cheng, additional, Liu, Chang-Hsiu, additional, Chan, Hoi-Fong, additional, Lee, Siu-Pak, additional, Sun, Ming-Hui, additional, Ke, Li-Ying, additional, Chen, Po-Lin, additional, Lee, Yu-Shan, additional, Ong, Cheung-Ter, additional, Wu, Chi-Shun, additional, Hsu, Yung-Chu, additional, Su, Yu-Hsiang, additional, Hung, Ling-Chien, additional, Lee, Jiunn-Tay, additional, Lin, Jiann-Chyun, additional, Hsu, Yaw-Don, additional, Peng, Giia-Sheun, additional, Hsu, Chang-Hung, additional, Lin, Chun-Chieh, additional, Yen, Che-Hung, additional, Cheng, Chun-An, additional, Sung, Yueh-Feng, additional, Chen, Yuan-Liang, additional, Lien, Ming-Tung, additional, Chou, Chung-Hsing, additional, Liu, Chia-Chen, additional, Yang, Fu-Chi, additional, Wu, Yi-Chung, additional, Tso, An-Chen, additional, Lai, Yu- Hua, additional, Chiang, Chun-I., additional, Tsai, Chia-Kuang, additional, Liu, Meng-Ta, additional, Lin, Ying-Che, additional, Hsu, Yu-Chuan, additional, Chiang, Tsuey-Ru, additional, Liao, Pin-Wen, additional, Lee, Mei-Ching, additional, Chen, Jen-Tse, additional, Lie, Sian-King, additional, Sun, Mu-Chien, additional, Hsiao, Pi-Ju, additional, Chen, Wei-Liang, additional, Chen, Ta-Cheng, additional, Chang, Chen-Shu, additional, Lai, Chien-Hsu, additional, Chuang, Chieh-Sen, additional, Chen, Yen-Yu, additional, Lin, Shinn-Kuang, additional, Su, Yu-Chin, additional, Shiao, Jen-Lun, additional, Yang, Fu-Yi, additional, Liu, Chih-Yang, additional, Chiang, Han-Lin, additional, Chen, Guei-Chiuan, additional, Hsu, Po-Jen, additional, Chang, Chun-Yuan, additional, Lin, I.-sheng, additional, Chien, Chung-Hsien, additional, Chang, Yang-Chuang, additional, Chen, Ping-Kun, additional, Hsiao, Yu-Jen, additional, Fang, Chen-Wen, additional, Chen, Yu-Wei, additional, Lee, Kuo-Ying, additional, Lin, Yun-Yu, additional, Li, Chen-Hua, additional, Tsai, Hui-Fen, additional, Hsieh, Chuan-Fa, additional, Yang, Chih-Dong, additional, Liaw, Shiumn-Jen, additional, Liao, How-Chin, additional, Yeh, Shoou-Jeng, additional, Wu, Ling-Li, additional, Hsieh, Liang-Po, additional, Lee, Yong-Hui, additional, Chen, Chung-Wen, additional, Hsu, Chih-Shan, additional, Jhih, Ye-Jian, additional, Zhuang, Hao-Yu, additional, Pan, Yan-Hong, additional, Shih, Shin-An, additional, Chen, Chin-I., additional, Sung, Jia-Ying, additional, Weng, Hsing-Yu, additional, Teng, Hao-Wen, additional, Lee, Jing-Er, additional, Huang, Chih-Shan, additional, Chao, Shu-Ping, additional, Yuan, Rey-Yue, additional, Sheu, Jau-Jiuan, additional, Yu, Jia-Ming, additional, Ho, Chun-Sum, additional, Lin, Ting-Chun, additional, Yu, Shih-Chieh, additional, Chen, Jiunn-Rong, additional, Tsai, Song-Yen, additional, Hung, Chao-Hsien, additional, Lee, Chia Fang, additional, Yang, Sheng-Kung, additional, Chen, Chih-Lin, additional, Lin, Wei, additional, Tseng, Hung-Pin, additional, Liu, Chin-Hsiung, additional, Lin, Chun-Liang, additional, Lin, Hung-Chih, additional, Chen, Pi-Tzu, additional, Hu, Chaur-Jong, additional, Chan, Lung, additional, Chi, Nai-Fang, additional, Chern, Chang-Ming, additional, Lin, Chun-Jen, additional, Wang, Shuu-Jiun, additional, Hsu, Li-Chi, additional, Wong, Wen-Jang, additional, Lee, I-Hui, additional, Yen, Der-Jen, additional, Tsai, Ching-Piao, additional, Kwan, Shang-Yeong, additional, Soong, Bing-Wen, additional, Chen, Shih-Pin, additional, Liao, Kwong-Kum, additional, Lin, Kung-Ping, additional, Chen, Chien, additional, Shan, Din-E., additional, Fuh, Jong-Ling, additional, Wang, Pei-Ning, additional, Lee, Yi-Chung, additional, Yu, Yu-Hsiang, additional, Huang, Hui-Chi, additional, Tsai, Jui-Yao, additional, Wu, Ming-Hsiu, additional, Chiang, Szu-Yi, additional, Wang, Chiung-Yao, additional, Hsu, Ming-Chin, additional, Chen, Chien-Chung, additional, Yeh, Po-Yen, additional, Tsai, Yu-Tai, additional, Wang, Ko-Yi, additional, Chen, Tsang-Shan, additional, Hsieh, Cheng-Yang, additional, Chen, Wei-Fen, additional, Yip, Ping-Keung, additional, Wang, Vinchi, additional, Wang, Kaw-Chen, additional, Tsai, Chung-Fen, additional, Chen, Chao-Ching, additional, Liu, Yi-Chien, additional, Chen, Shao-Yuan, additional, Zhao, Zi-Hao, additional, Wei, Zhi-Peng, additional, Wu, Shey-Lin, additional, Liu, Ching-Kuan, additional, Lin, Ryh-Huei, additional, Chu, Ching-Hua, additional, Yan, Sui-Hing, additional, Lin, Yi-Chun, additional, Chen, Pei-Yun, additional, Hsiao, Sheng-Huang, additional, Yip, Bak-Sau, additional, Tsai, Pei-Chun, additional, Chou, Ping-Chen, additional, Kuo, Tsam-Ming, additional, Lee, Yi-Chen, additional, Chiu, Yi-Pin, additional, Tsai, Kun-Chang, additional, Liao, Yi-Sheng, additional, Tsai, Ming-Jun, additional, and Kao, Hsin-Yi, additional

Published
2018
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22. Abstract WP121: One-Year Risk of Recurrent Stroke Associated With Vertebral and Basilar Artery Stenosis and Occlusion in a Cohort of 10,515 Ischemic Stroke Patients

Author

Qureshi, Adnan, primary, Qureshi, Mushtaq, additional, Jeng, Jiann-Shing, additional, Lien, Li-Ming, additional, Hu, Chaur-Jong, additional, Lee, Jiunn-Tay, additional, Lai, Ta-Chang Lai, additional, Liu, Chung-Hsiang, additional, Chen, Chih-Hung, additional, Chen, Po-Lin, additional, Chen, Tsang-Shan, additional, Li, Jie-Yuan, additional, Lin, Cheng-Li, additional, and Hsu, Chung, additional

Published
2018
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23. Cholesterol Levels Are Associated with 30-day Mortality from Ischemic Stroke in Dialysis Patients

Author

Wang, I.-Kuan, primary, Liu, Chung-Hsiang, additional, Yen, Tzung-Hai, additional, Jeng, Jiann-Shing, additional, Hsu, Shih-Pin, additional, Chen, Chih-Hung, additional, Lien, Li-Ming, additional, Lin, Ruey-Tay, additional, Chen, An-Chih, additional, Lin, Huey-Juan, additional, Chi, Hsin-Yi, additional, Lai, Ta-Chang, additional, Sun, Yu, additional, Lee, Siu-Pak, additional, Sung, Sheng-Feng, additional, Chen, Po-Lin, additional, Lee, Jiunn-Tay, additional, Chiang, Tsuey-Ru, additional, Lin, Shinn-Kuang, additional, Muo, Chih-Hsin, additional, Ma, Henry, additional, Wen, Chi-Pang, additional, Sung, Fung-Chang, additional, Hsu, Chung Y., additional, Tsai, Chon-Haw, additional, Huang, Wei-Shih, additional, Lu, Chung-Ta, additional, Tsai, Tzung-Chang, additional, Tseng, Chun-Hung, additional, Lin, Kang-Hsu, additional, Shyn, Woei-Cherng, additional, Yang, Yu-Wan, additional, Liu, Yen-Liang, additional, Cho, Der-Yang, additional, Chen, Chun-Chung, additional, Tang, Sung-Chun, additional, Tsai, Li-Kai, additional, Yeh, Shin-Joe, additional, Chen, Han-Jung, additional, Chang, Cheng-Sen, additional, Kuo, Hung-Chang, additional, Lee, Lian-Hui, additional, Tsui, Huan-Wen, additional, Tsou, Jung-Chi, additional, Wang, Yan-Tang, additional, Tai, Yi-Cheng, additional, Tsai, Kun-Chang, additional, Chen, Yen-Wen, additional, Lu, Kan, additional, Liliang, Po-Chao, additional, Tsai, Yu-Tun, additional, Liang, Cheng-Loong, additional, Wang, Kuo-Wei, additional, Wang, Hao-Kuang, additional, Chen, Jui-Sheng, additional, Chen, Po-Yuan, additional, Chye, Cien-Leong, additional, Tzeng, Wei-Jie, additional, Wu, Pei-Hua, additional, Sung, Pi-Shan, additional, Hsieh, Han-Chieh, additional, Su, Hui-Chen, additional, Chiu, Hou-Chang, additional, Chen, Wei-Hung, additional, Bai, Chyi-Huey, additional, Huang, Tzu-Hsuan, additional, Lau, Chi-Ieong, additional, Wu, Ya-Ying, additional, Yeh, Hsu-Ling, additional, Chang, Anna, additional, Lin, Ching-Huang, additional, Yen, Cheng-Chang, additional, Chen, Chun-Hung, additional, Khor, Gim-Thean, additional, Chao, A-Ching, additional, Lin, Hsiu-Fen, additional, Huang, Poyin, additional, Ke, Der-Shin, additional, Chang, Chia-Yu, additional, Yeh, Poh-Shiow, additional, Lin, Kao-Chang, additional, Cheng, Tain-Junn, additional, Chou, Chih-Ho, additional, Yang, Chun-Ming, additional, Shen, Hsiu-Chu, additional, Tsai, Shih-Jei, additional, Lu, Tsong-Ming, additional, Kung, Sheng-Ling, additional, Lee, Mei-Ju, additional, Chou, Hsi-Hsien, additional, Pan, Chou-Hsiung, additional, Chan, Po-Chi, additional, Hsu, Min-Hsien, additional, Chang, Wei-Lun, additional, Huang, Zhi-Zang, additional, Shoung, Hai-Ming, additional, Lo, Yi-Chen, additional, Wang, Fu-Hwa, additional, Yin, Jiu-Haw, additional, Wang, Chung-Jen, additional, Wang, Kai-Chen, additional, Chen, Li-Mei, additional, Denq, Jong-Chyou, additional, Lu, Chien-Jung, additional, Lin, Cheng-Huai, additional, Huang, Chieh-Cheng, additional, Liu, Chang-Hsiu, additional, Chan, Hoi-Fong, additional, Sun, Ming-Hui, additional, Ke, Li-Ying, additional, Lee, Yu-Shan, additional, Ong, Cheung-Ter, additional, Wu, Chi-Shun, additional, Hsu, Yung-Chu, additional, Su, Yu-Hsiang, additional, Hung, Ling-Chien, additional, Lin, Jiann-Chyun, additional, Hsu, Yaw-Don, additional, Peng, Giia-Sheun, additional, Hsu, Chang-Hung, additional, Lin, Chun-Chieh, additional, Yen, Che-Hung, additional, Cheng, Chun-An, additional, Sung, Yueh-Feng, additional, Chen, Yuan-Liang, additional, Lien, Ming-Tung, additional, Chou, Chung-Hsing, additional, Liu, Chia-Chen, additional, Yang, Fu-Chi, additional, Wu, Yi-Chung, additional, Tso, An-Chen, additional, Lai, Yu-Hua, additional, Chiang, Chun-I, additional, Tsai, Chia-Kuang, additional, Liu, Meng-Ta, additional, Lin, Ying-Che, additional, Hsu, Yu-Chuan, additional, Lee, Mei-Ching, additional, Huang, Pai-Hao, additional, Lie, Sian-King, additional, Liao, Pin-Wen, additional, Chen, Jen-Tse, additional, Sun, Mu-Chien, additional, Lai, Tien-Pao, additional, Chen, Wei-Liang, additional, Chen, Yen-Chun, additional, Chen, Ta-Cheng, additional, Wang, Wen-Fu, additional, Lee, Kwo-Whei, additional, Chang, Chen-Shu, additional, Lai, Chien-Hsu, additional, Shih, Siao-Ya, additional, Chuang, Chieh-Sen, additional, Chen, Yen-Yu, additional, Chen, Chien-Min, additional, Su, Yu-Chin, additional, Hsiao, Cheng-Lun, additional, Yang, Fu-Yi, additional, Liu, Chih-Yang, additional, Chiang, Han-Lin, additional, Chang, Chun-Yuan, additional, Lin, I-sheng, additional, Chien, Chung-Hsien, additional, Chang, Yang-Chuang, additional, Chen, Ping-Kun, additional, Chiu, Pai-Yi, additional, Hsiao, Yu-Jen, additional, Fang, Chen-Wen, additional, Chen, Yu-Wei, additional, Lee, Kuo-Ying, additional, Lin, Yun-Yu, additional, Li, Chen-Hua, additional, Tsai, Hui-Fen, additional, Hsieh, Chuan-Fa, additional, Yang, Chih-Dong, additional, Liaw, Shiumn-Jen, additional, Liao, How-Chin, additional, Yeh, Shoou-Jeng, additional, Wu, Ling-Li, additional, Hsieh, Liang-Po, additional, Lee, Yong-Hui, additional, Chen, Chung-Wen, additional, Hsu, Chih-Shan, additional, Jhih, Ye-Jian, additional, Zhuang, Hao-Yu, additional, Pan, Yan-Hong, additional, Shih, Shin-An, additional, Chen, Chin-I, additional, Sung, Jia-Ying, additional, Weng, Hsing-Yu, additional, Teng, Hao-Wen, additional, Lee, Jing-Er, additional, Huang, Chih-Shan, additional, Chao, Shu-Ping, additional, Yuan, Rey-Yue, additional, Sheu, Jau- Jiuan, additional, Yu, Jia-Ming, additional, Ho, Chun-Sum, additional, Lin, Ting-Chun, additional, Yu, Shih-Chieh, additional, Chen, Jiunn-Rong, additional, Tsai, Song-Yen, additional, Wei, Cheng-Yu, additional, Yang, Chao-Nan, additional, Hung, Chao-Hsien, additional, Shih, Ian, additional, Tseng, Hung-Pin, additional, Liu, Chin-Hsiung, additional, Lin, Chun-Liang, additional, Lin, Hung-Chih, additional, Chen, Pi-Tzu, additional, Hu, Chaur-Jong, additional, Chi, Nai-Fang, additional, Chan, Lung, additional, Chern, Chang-Ming, additional, Lin, Chun-Jen, additional, Wang, Shuu-Jiun, additional, Hsu, Li-Chi, additional, Wong, Wen-Jang, additional, Lee, I-Hui, additional, Yen, Der-Jen, additional, Tsai, Ching-Piao, additional, Kwan, Shang-Yeong, additional, Soong, Bing-Wen, additional, Chen, Shih-Pin, additional, Liao, Kwong-Kum, additional, Lin, Kung-Ping, additional, Chen, Chien, additional, Shan, Din-E, additional, Fuh, Jong-Ling, additional, Wang, Pei-Ning, additional, Lee, Yi-Chung, additional, Yu, Yu-Hsiang, additional, Huang, Hui-Chi, additional, Tsai, Jui-Yao, additional, Wu, Ming-Hsiu, additional, Chen, Shi-Cheng, additional, Chiang, Szu-Yi, additional, Wang, Chiung-Yao, additional, Hsu, Ming-Chin, additional, Chen, Chien-Chung, additional, Yeh, Po-Yen, additional, Tsai, Yu-Tai, additional, Wang, Ko-Yi, additional, Chen, Tsang-Shan, additional, Yip, Ping-Keung, additional, Wang, Vinchi, additional, Wang, Kaw-Chen, additional, Tsai, Chung-Fen, additional, Chen, Chao-Ching, additional, Chen, Chih-Hao, additional, Liu, Yi-Chien, additional, Chen, Shao-Yuan, additional, Zhao, Zi-Hao, additional, Wei, Zhi-Peng, additional, Wu, Shey-Lin, additional, Liu, Ching-Kuan, additional, Lin, Ryh-Huei, additional, Chu, Ching-Hua, additional, Yan, Sui-Hing, additional, Lin, Yi-Chun, additional, Chen, Pei-Yun, additional, Hsiao, Sheng-Huang, additional, Yip, Bak-Sau, additional, Tsai, Pei-Chun, additional, Chou, Ping-Chen, additional, Kuo, Tsam-Ming, additional, Lee, Yi-Chen, additional, Chiu, Yi-Pin, additional, Liao, Yi-Sheng, additional, Tsai, Ming-Jun, additional, and Kao, Hsin-Yi, additional

Published
2017
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24. One-Year Risk of Recurrent Stroke and Death Associated with Vertebrobasilar Artery Stenosis and Occlusion in a Cohort of 10,515 Patients.

Author

Qureshi, Adnan I., Qureshi, Mushtaq H., Lien, Li-Ming, Lee, Jiunn-Tay, Jeng, Jiann-Shing, Hu, Chaur-Jong, Lai, Ta-Chang, Liu, Chung-Hsiang, Chen, Chih-Hung, Chen, Po-Lin, Chen, Tsang-Shan, Li, Jie-Yuan, Lin, Cheng-Li, and Hsu, Chung Y.

Subjects
VERTEBROBASILAR insufficiency, STROKE, TRANSIENT ischemic attack, COMPUTED tomography, MAGNETIC resonance imaging
Abstract

>bold<>italic/italic<>/bold< The natural history of vertebrobasilar artery (VBA) stenosis or occlusion remains understudied. >bold<>italic/italic<>/bold< Patients with diagnosis of ischemic stroke or transient ischemic attack (TIA) who were noted to have VBA stenosis based on computed tomography or magnetic resonance imaging or catheter-based angiogram were selected from Taiwan Stroke Registry. Cox proportional hazards model was used to determine the hazards ratio (HR) of recurrent stroke and death within 1 year of index event in various groups based on severity of VBA stenosis (none to mild: 0–49%; moderate to severe: 50–99%: occlusion: 100%) after adjusting for differences in demographic and clinical characteristics between groups at baseline evaluation. >bold<>italic/italic<>/bold< None to mild or moderate to severe VBA stenosis was diagnosed in 6972 (66%) and 3,137 (29.8%) among 10,515 patients, respectively, and occlusion was identified in 406 (3.8%) patients. Comparing with patients who showed none to mild stenosis of VBA, there was a significantly higher risk of recurrent stroke (HR 1.21, 95% CI 1.01–1.45) among patients with moderate to severe VBA stenosis. There was a nonsignificantly higher risk of recurrent stroke (HR 1.49, 95% CI 0.99–2.22) and significantly higher risk of death (HR 2.21, 95% CI 1.72–2.83), among patients with VBA occlusion after adjustment of potential confounders. >bold<>italic/italic<>/bold< VBA stenosis or occlusion was relatively prevalent among patients with TIA or ischemic stroke and associated with higher risk of recurrent stroke and death in patients with ischemic stroke or TIA who had large artery atherosclerosis>bold<>italic<.>/italic<>/bold< [ABSTRACT FROM AUTHOR]

Published
2019
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25. Pioglitazone, a PPAR-γ Activator, Stimulates BKCa but Suppresses IK M in Hippocampal Neurons.

Author

Chen, Tsang-Shan, Lai, Ming-Chi, Hung, Te-Yu, Lin, Kao-Min, Huang, Chin-Wei, and Wu, Sheng-Nan

Subjects
PIOGLITAZONE, PEROXISOME proliferator-activated receptors, NEURAL physiology, THERAPEUTICS
Abstract

Pioglitazone (PIO), a thiazolidinedone, was reported to stimulate peroxisome proliferator-activated receptor-γ (PPAR-γ) with anti-inflammatory, anti-proliferative, anti-diabetic, and antidepressive activities. However, whether this compound exerts any perturbations on Ca2+-activated K+ and M-type K+ currents in central neurons remains largely unresolved. In this study, we investigated the effects of PIO on these potassium currents in hippocampal neurons (mHippoE-14). In whole-cell current recordings, the presence of PIO (10 μM) increased the amplitude of Ca2+-activated K+ current [ I K(Ca)] in mHippoE-14 cells. PIO-induced stimulation of I K(Ca) observed in these cells was reversed by subsequent addition of paxilline, yet not by TRAM-39 or apamin. In inside-out current recordings, PIO applied to the bath concentration-dependently increased the activity of large-conductance Ca2+-activated K+ (BKCa) channels with an EC50 value of 7.6 μM. Its activation of BKCa channels in mHippoE-14 cells was voltage-dependent and accompanied by both a lengthening in mean open time and a shortening in slow component of mean closed time. The activation curve of BKCa channels after addition of PIO was shifted to less depolarized potential without any change in the gating charge. PIO also suppressed the amplitude of M-type K+ currents inherently in mHippoE-14 neurons. Taken together, in addition to its agonistic action on PPAR-γ, PIO-induced perturbation of these potassium channels may be responsible for its widely pharmacological actions on hippocampal neurons. [ABSTRACT FROM AUTHOR]

Published
2018
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27. Low cholesterol level associated with severity and outcome of spontaneous intracerebral hemorrhage: Results from Taiwan Stroke Registry.

Author

Chen, Yu-Wei, Li, Chen-Hua, Yang, Chih-Dong, Liu, Chung-Hsiang, Chen, Chih-Hung, Sheu, Jau-Jiuan, Lin, Shinn-Kuang, Chen, An-Chih, Chen, Ping-Kun, Chen, Po-Lin, Yeh, Chung-Hsin, Chen, Jiunn-Rong, Hsiao, Yu-Jen, Lin, Ching-Huang, Hsu, Shih-Pin, Chen, Tsang-Shan, Sung, Sheng-Feng, Yu, Shih-Chieh, Muo, Chih-Hsin, and Wen, Chi Pang

Subjects
CEREBRAL hemorrhage treatment, PHYSIOLOGICAL effects of cholesterol, HEALTH outcome assessment, NEUROLOGY
Abstract

The relationship between cholesterol level and hemorrhagic stroke is inconclusive. We hypothesized that low cholesterol levels may have association with intracerebral hemorrhage (ICH) severity at admission and 3-month outcomes. This study used data obtained from a multi-center stroke registry program in Taiwan. We categorized acute spontaneous ICH patients, based on their baseline levels of total cholesterol (TC) measured at admission, into 3 groups with <160, 160–200 and >200 mg/dL of TC. We evaluated risk of having initial stroke severity, with National Institutes of Health Stroke Scale (NIHSS) >15 and unfavorable outcomes (modified Rankin Scale [mRS] score >2, 3-month mortality) after ICH by the TC group. A total of 2444 ICH patients (mean age 62.5±14.2 years; 64.2% men) were included in this study and 854 (34.9%) of them had baseline TC <160 mg/dL. Patients with TC <160 mg/dL presented more often severe neurological deficit (NIHSS >15), with an adjusted odds ratio [aOR] of 1.80; 95% confidence interval [CI], 1.41–2.30), and 3-month mRS >2 (aOR, 1.41; 95% CI, 1.11–1.78) using patients with TC >200 mg/dL as reference. Those with TC >160 mg/dL and body mass index (BMI) <22 kg/m2 had higher risk of 3-month mortality (aOR 3.94, 95% CI 1.76–8.80). Prior use of lipid-lowering drugs (2.8% of the ICH population) was not associated with initial severity and 3-month outcomes. A total cholesterol level lower than 160 mg/dL was common in patients with acute ICH and was associated with greater neurological severity on presentation and poor 3-month outcomes, especially with lower BMI. [ABSTRACT FROM AUTHOR]

Published
2017
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34. Pioglitazone, a PPAR-γ Activator, Stimulates BK Ca but Suppresses IK M in Hippocampal Neurons.

Author

Chen TS, Lai MC, Hung TY, Lin KM, Huang CW, and Wu SN

Abstract

Pioglitazone (PIO), a thiazolidinedone, was reported to stimulate peroxisome proliferator-activated receptor-γ (PPAR-γ) with anti-inflammatory, anti-proliferative, anti-diabetic, and antidepressive activities. However, whether this compound exerts any perturbations on Ca 2+ -activated K + and M-type K + currents in central neurons remains largely unresolved. In this study, we investigated the effects of PIO on these potassium currents in hippocampal neurons (mHippoE-14). In whole-cell current recordings, the presence of PIO (10 μM) increased the amplitude of Ca 2+ -activated K + current [ I K(Ca) ] in mHippoE-14 cells. PIO-induced stimulation of I K(Ca) observed in these cells was reversed by subsequent addition of paxilline, yet not by TRAM-39 or apamin. In inside-out current recordings, PIO applied to the bath concentration-dependently increased the activity of large-conductance Ca 2+ -activated K + (BK Ca ) channels with an EC 50 value of 7.6 μM. Its activation of BK Ca channels in mHippoE-14 cells was voltage-dependent and accompanied by both a lengthening in mean open time and a shortening in slow component of mean closed time. The activation curve of BK Ca channels after addition of PIO was shifted to less depolarized potential without any change in the gating charge. PIO also suppressed the amplitude of M-type K + currents inherently in mHippoE-14 neurons. Taken together, in addition to its agonistic action on PPAR-γ, PIO-induced perturbation of these potassium channels may be responsible for its widely pharmacological actions on hippocampal neurons.

Published
2018
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35. Periventricular heterotopia.

Author

Chen TS and Lee JD

Subjects
Adult, Female, Humans, Lateral Ventricles pathology, Magnetic Resonance Imaging, Periventricular Nodular Heterotopia pathology
Published
2013

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